Babu, US
Baiju Zacharia Babu, Waukesha, WI US
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20120183119 | MULTI-SLICE CT DETECTOR WITH TILEABLE PACKAGING STRUCTURE - A CT system is disclosed that includes detector modules positioned on a rotatable gantry configured to receive x-rays attenuated by an object. Each detector module includes a module frame, a plurality of tileable sub-modules on the module frame aligned along a Z-axis thereof to receive the x-rays attenuated by the object and convert the x-rays to digital signals, and an electronics board connected to the plurality of sub-modules to receive the digital signals. Each sub-module further includes an array of detector elements to receive x-rays attenuated through the object and convert the x-rays into analog electrical signals, an ASIC electronics package coupled to the array of detector elements to receive the analog electrical signals and convert the analog electrical signals to digital signals, and a flex circuit connected to the ASIC electronics package to receive the digital signals and transfer the digital signals to the electronics board. | 07-19-2012 |
20150071401 | PRECISION SELF-ALIGNING CT DETECTOR SENSORS - CT detector modules are disclosed that include a module frame and a plurality of tileable detector sensors positioned on the module frame. Each of the tileable detector sensors includes an array of detector elements and a mounting structure directly or indirectly coupled to the detector elements to provide for a mounting and alignment of the detector sensor to the module frame. The mounting structure includes an alignment plate positioned generally opposite the array of detector elements, with the alignment plate having alignment pins forming a datum structure to align the detector sensor on the module frame and one or more threaded bosses configured to receive a fastener therein that secures the detector sensor to the module frame. The module frame includes keyed features that receive the alignment pins when the detector sensors are mounted on the module frame, so as to align the detector sensors on the module frame. | 03-12-2015 |
Binu J. Babu, Houston, TX US
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20160092115 | IMPLEMENTING STORAGE POLICIES REGARDING USE OF MEMORY REGIONS - Example implementations relate to implementing storage policies regarding use of memory regions. In example implementations, a first memory region having a lower access latency than a second memory region may be identified. The first and second memory regions may be identical in memory type. A plurality of storage policies regarding use of the first and second memory regions may be implemented. | 03-31-2016 |
Binu John Babu, Houston, TX US
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20110004703 | ILLEGAL COMMAND HANDLING - A circuit for handling an illegal command embodies a control decode stage, illegal command handling stage and an output stage. The control decode circuit receives a clock signal, receives and decodes an external command, and latches the decoded external command based on the clock signal to generate a first signal. The first device is coupled to the control decode circuit for receiving the first signal, receives a second signal indicating whether the illegal command is detected in the external command, and generates a third signal based on the first and the second signals. The output circuit is coupled to the first device, receives the clock signal and the third signal, and generates a first output based on the clock signal and the third signal. If there is an illegal command, then there will be no control output generated. On the other hand, in the absence of an illegal command a control output will be generated. | 01-06-2011 |
Charles Babu, Arlington, TX US
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20130296377 | Complement pathway modulators and uses thereof - The present invention provides a compound of formula I: | 11-07-2013 |
20150250767 | Complement pathway modulators and uses thereof - The present invention provides a compound of formula I: | 09-10-2015 |
20160024079 | Complement Factor B inhibitors and uses there of - The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents. | 01-28-2016 |
Darryl S. Babu, Racine, WI US
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20080281478 | Programmable Automatic Trim Control System For Marine Applications - A programmable automatic trim control system for marine applications preferably includes a controller, a control panel, at least one display device and a plurality of sensors. The controller receives input from the control panel and the plurality of sensors. Each display device shows various data from the controller. Each sensor monitors a single drive device, trim device or operational parameter. The controller further includes output ports connected to the drive devices and trim devices for the control thereof. The trim control system preferably includes a manual mode, a diagnostic mode, a program mode and an automatic mode. The positions and/or settings of the trim and drive devices and operational parameters are set in the program mode and recorded in the controller. Data stored in the controller is accessed and utilized by the trim control system when in the automatic mode. | 11-13-2008 |
Desarazu Krishna Babu, Addison, TX US
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20100286917 | METHOD AND SYSTEM FOR REPRESENTING WELLS IN MODELING A PHYSICAL FLUID RESERVOIR - The disclosure is directed to a method of representing fluid flow response to imposed conditions in a physical fluid reservoir through wells. The invention utilizes techniques and formulas of unprecedented accuracy and speed for computations for a fundamental element in analysis of fluid movement through subterranean reservoirs—the calculation of Green's and Neumann functions in finite three-dimensional space. The method includes modeling of pressure and/or flow rate observables at wells in said reservoir using an easily computable, closed-form Green's or Neumann function for a linear well segment in arbitrary orientation within a three dimensional cell of spatially invariant but anisotropic permeability. The method further includes the modeling of fluid flow in the physical fluid reservoir with an assemblage of linear well segments operating in unison with uniform flux density to represent arbitrary well trajectory. The method further includes modeling reservoir flow through one or more linear well segments of non-uniform flux related by a constitutive expression linking pressure distribution and flow rate within the well. The method further includes generalization through integration of easily computable Green's or Neumann functions to represent fractures or fractured wells in modeling fluid flow in a physical reservoir. The system includes modeling fluid flow through a mesh representation of the physical fluid reservoir containing one or more wells represented by easily computable Green's or Neumann functions. The system further includes modeling of flow in the physical reservoir via a numerical method in which the values of pressure and flux assigned to the mesh are related to observables at the well using aforementioned easily computable Green's or Neumann functions. The system further includes the coupling of well and mesh values within the numerical solution method for well observation or feedback control. The system still further includes the localization of the well model to the properties assigned to only those mesh elements penetrated by the well using boundary integral equation methods. The invention also incorporates the addition of transients in fluid flow towards a steady or pseudo-steady state, and use thereof, in the above constructs. | 11-11-2010 |
Desarazu Krishna Babu, Spring, TX US
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20120303342 | METHOD AND SYSTEM FOR REPRESENTING WELLS IN MODELING A PHYSICAL FLUID RESERVOIR - The disclosure is directed to a method of representing fluid flow response to imposed conditions in a physical fluid reservoir through wells. The invention utilizes techniques and formulas of unprecedented accuracy and speed for computer computation of Green's and Neumann functions in finite three-dimensional space for arbitrarily-oriented line sources in anisotropic media. The method includes the modeling of fluid flow in physical fluid reservoirs with an assemblage of linear well segments, characterizing arbitrary well trajectory, operating in unison with flux density coupled to flow rate within the well through a constitutive expression linking pressure distribution and flow. The method further includes generalization to complex fracture sets or fractured wells in modeling fluid flow in a reservoir, coupled use of such computations within a mesh representation of the physical fluid reservoir with isolation of well cell contributions, and extension to modeling of heterogeneous reservoirs and pressure transients. | 11-29-2012 |
Giddi Phani Babu, Beaverton, OR US
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20090128596 | Increasing Inkjet Printer Page Yield - A method for increasing a page yield of an inkjet printer that includes receiving a plurality of print jobs for printing at the inkjet printer, adding the plurality of print jobs to a job queue, calculating a first cumulative amount of ink for use by the inkjet printer to print on media for all of the plurality of print jobs at once, calculate a second cumulative amount of ink for use to maintain the inkjet printer for printing the plurality of print jobs at once, calculating a cumulative page yield for printing all of the plurality of print jobs in the job queue at once by the inkjet printer based on the calculated first and second cumulative amounts of ink, determining whether the cumulative page yield is greater than or equal to a predetermined threshold, and upon the determination that the cumulative page yield is greater than or equal to a predetermined threshold, directing the inkjet printer to print the plurality of print jobs at once. | 05-21-2009 |
Govindarajulu Babu US
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20110281865 | NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUTED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES - The present invention provides, inter alia, compounds of formula I as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them. | 11-17-2011 |
Jennifer B. Babu, Purcellville, VA US
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20090028131 | TEST AUTOMATION FOR AN INTEGRATED TELEPHONY CALL MANAGEMENT SERVICE - A test application includes instructions for configuring a digital cross connect. A first modem and a second modem are each connected to at least one telecommunications network and a digital cross connect. An integrated telephony call management service (ITCMS) client includes computer-executable instructions stored on a computer-readable medium included in the test computer. | 01-29-2009 |
Karishma Babu, Plano, TX US
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20140259167 | BEHAVIOR BASED APPLICATION BLACKLISTING - A network system and a method for detecting behavior in a network device are provided. The method includes generating a list of one or more prohibited behaviors, generating a list of one or more corrective actions, mapping each of the one or more prohibited behaviors to at least one of the one or more corrective actions, identifying one or more of a user, a process or an application involved in a prohibited behavior, and applying, to the one or more of the user, the process or the application involved in the prohibited behavior, the at least one of the one or more corrective actions mapped to the prohibited behavior performed. | 09-11-2014 |
Kartik Suchindra Babu, Pittsburgh, PA US
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20160092805 | SYSTEM AND METHOD FOR WORKFLOW MANAGEMENT - A workflow management system for managing the storage, retrieval, and transport of items in a warehouse includes a voice-directed mobile terminal. The system also includes a server computer in communication with the voice-directed mobile terminal. The server computer includes a tasking module for transmitting task data to the voice-directed mobile terminal. The server computer also includes a workflow-analysis module for generating, based at least in part upon an analysis of workflow dialog between the voice-directed mobile terminal and the user, performance data relating to the performance of tasks associated with the storage, retrieval, and/or transport of the items. | 03-31-2016 |
Michael Babu, Fairfield, CT US
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20100011741 | GAS TURBINE ENGINE WITH DUAL FANS DRIVEN ABOUT A CENTRAL CORE AXIS - A gas turbine engine includes a compressor section, a combustor section and a turbine section, all arranged about a central axis. A turbine rotor drives a driveshaft for rotation on the central axis. The driveshaft in turn drives at least two fan rotors on axes parallel to, but spaced from, the central axis. The fan rotors each deliver a portion of the air they move into a central inlet for delivering the air to the compressor section. In addition, the majority of the air moved by the plurality of fan rotors passes between a cowl and an outer periphery of a housing for the central core of the engine. This bypass air provides propulsion as is known in the turbojet art. | 01-21-2010 |
20150114772 | ROTOR BRAKE - A brake disc of a rotor brake is provided including a generally cylindrical body having a first planar surface, a second, opposite planar surface, and a central opening extending there through. A plurality of first connection members extend generally outwardly from the first planar surface. The first connection members are generally equidistantly spaced about a diameter of the first planar surface. A plurality of second connection members extend generally outwardly from the second planar surface. The second connection members are generally equidistantly spaced about a diameter of the second planar surface. | 04-30-2015 |
Nadarajan S. Babu, Philadelphia, PA US
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20080220181 | Method of loading a nanotube structure and loaded nanotube structure - Nanotubes loaded with materials, such as active species, and methods to load materials into nanotubes are disclosed. The method includes flowing a medium containing the material to be loaded through the interior volume of the nanotube, wherein it is retained, optionally by a crosslinking or polymerization reaction. Flowing the medium occurs under different conditions and processes, including centrifuging and size exclusion methods. | 09-11-2008 |
Premkumar Babu, Allentown, PA US
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20150297115 | LIGHT BASED LOCATION AND IDENTIFICATION OF IMPLANTED MEDICAL DEVICES - A method of determining information regarding an implanted medical device. The method includes scanning an infrared or near-infrared laser over a target area wherein a medical device having at least one light affective area defined thereon is implanted; sensing reflected light from the scanned area; processing the reflected light and creating an image which indicates the light affective area based on a difference in the sensed light; and displaying the created image. A system for determining information regarding an implanted medical device is also provided. | 10-22-2015 |
Sachidananda R. Babu, Greenbelt, MD US
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20090311860 | BLOCKING CONTACTS FOR N-TYPE CADMIUM ZINC TELLURIDE - A process for applying blocking contacts on an n-type CdZnTe specimen includes cleaning the CdZnTe specimen; etching the CdZnTe specimen; chemically surface treating the CdZnTe specimen; and depositing blocking metal on at least one of a cathode surface and an anode surface of the CdZnTe specimen. | 12-17-2009 |
Seilesh Babu, Novi, MI US
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20140303728 | Ossicle prosthesis comprising a built-up attaching element - An ossicular prosthesis formed as a sound-conducting, elongated prosthesis body has a first coupling element designed as a tympanic membrane top plate or a clip or a connecting piece to an actuator end piece of an active hearing implant and a second coupling element provided with an access opening into a receiving space designed as a bell or a clip for a mechanical connection of the prosthesis to the head of the stapes. The second coupling element has a backing section on an inner surface of the receiving space as an axial extension of the prosthesis body. The backing section protrudes from the prosthesis body into the receiving space. In an implanted state, the backing section bears against a head of the stapes and prevents a formation of a hollow space between the stapes and an inner surface of the receiving space in an axial extension of the elongated prosthesis body. As a result, additional degrees of freedom are obtained for individualized adaptation to anatomical circumstances of a specific patient in terms of shape, size and position of the patient's stapes bone. | 10-09-2014 |
Shivnath Babu, Durham, NC US
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20130254196 | COST-BASED OPTIMIZATION OF CONFIGURATION PARAMETERS AND CLUSTER SIZING FOR HADOOP - Cost-based optimization of configuration parameters and cluster sizing for distributed data processing systems are disclosed. According to an aspect, a method includes receiving at least one job profile of a MapReduce job. The method also includes using the at least one job profile to predict execution of the MapReduce job within a plurality of different predetermined settings of a distributed data processing system. Further, the method includes determining one of the predetermined settings that optimizes performance of the MapReduce job. The method may also include automatically adjusting the distributed data processing system to the determined predetermined setting. | 09-26-2013 |
Sudarsanam S. Babu, Dublin, OH US
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20100121472 | Remote High-Performance Computing Material Joining and Material Forming Modeling System and Method - A remote high-performance computing material joining and material forming modeling system ( | 05-13-2010 |
Sudarsanam Suresh Babu, Knoxville, TN US
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20150368766 | COBALT-FREE, GALLING AND WEAR RESISTANT AUSTENITIC STAINLESS STEEL HARD-FACING ALLOY - A strain-hardenable stainless steel alloy includes hard secondary phases dispersed in an austenitic primary phase, the alloy including 0.3-0.6% nitrogen by weight. | 12-24-2015 |
Surendra Chitti Babu, Tinley Park, IL US
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20100029104 | Pluggable cable connector - A pair manager for use in securing a twin-axial cable to a printed circuit board is described. The pair manager comprises a generally block-shaped portion containing a pair of channels. The channels extend from the front face to the rear face of the block-shaped portion. An integral flange and a pair of integral fingers extend perpendicularly from the front face of the block-shaped portion. The flange extends generally from the center of the front face and the fingers extend from opposite edges of the front face. The fingers and flange function as a partial shield cavity around each pair of conductors. This design helps to maintain better impedance matching when connecting twin-axial cables to a printed circuit board. | 02-04-2010 |
20120045942 | Pluggable Cable Connector - A pair manager for use in securing a twin-axial cable to a printed circuit board is described. The pair manager comprises a generally block-shaped portion containing a pair of channels. The channels extend from the front face to the rear face of the block-shaped portion. An integral flange and a pair of integral fingers extend perpendicularly from the front face of the block-shaped portion. The flange extends generally from the center of the front face and the fingers extend from opposite edges of the front face. The fingers and flange function as a partial shield cavity around each pair of conductors. This design helps to maintain better impedance matching when connecting twin-axial cables to a printed circuit board. | 02-23-2012 |
20120100744 | Communication Plug with Improved Crosstalk - A communication plug having a plug body and a plurality of contact pairs at least partially within the plug body, the contact pairs including an inherent asymmetric coupling between individual contacts of one of the contact pairs and other individual contacts of another of the contact pairs. Second asymmetric coupling elements are connected between the individual contacts of one of the contact pairs and the other individual contacts of another of the contact pairs. The second asymmetric coupling elements, when combined with the inherent asymmetric coupling, provide a balanced symmetric coupling between the individual contacts of one of the contact pairs and the other individual contacts of another of the contact pairs. | 04-26-2012 |
20120190218 | Pluggable Cable Connector - A pair manager for use in securing a twin-axial cable to a printed circuit board is described. The pair manager comprises a generally block-shaped portion containing a pair of channels. The channels extend from the front face to the rear face of the block-shaped portion. An integral flange and a pair of integral fingers extend perpendicularly from the front face of the block-shaped portion. The flange extends generally from the center of the front face and the fingers extend from opposite edges of the front face. The fingers and flange function as a partial shield cavity around each pair of conductors. This design helps to maintain better impedance matching when connecting twin-axial cables to a printed circuit board. | 07-26-2012 |
Surendra Chitti Babu, New Lenox, IL US
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20130077232 | THERMAL MANAGEMENT INFRASTRUCTURE FOR IT EQUIPMENT IN A CABINET - The present invention attempts to reduce the thermal resistance with the use of heat-transfer devices (e.g., vapor chambers) placed directly on the heat-generating components in IT equipment and the integration of a cold plate within the cabinet. In some embodiments, the present invention is a thermal management system comprising a cabinet-side thermal management system and a server-side thermal management system using moveable thermal components. | 03-28-2013 |
20130090011 | Backward Compatible Connectivity for High Data Rate Applications - The present invention provides a communication jack for connecting to one of a first plug and a second plug. The jack includes a housing, plug interface contacts, and coupling circuitry. The plug interface contacts are at least partially within said housing and include a plurality of contact pairs having at least a first contact pair and a second contact pair. The coupling circuitry is configured for engaging said first contact pair and said second contact pair when said first plug is inserted into said housing. The coupling circuitry is configured for disengaging from said first contact pair and said second contact pair when said second plug is inserted into said housing. | 04-11-2013 |
20140187077 | COMMUNICATION PLUG WITH IMPROVED CROSSTALK - A communication plug having a plug body and a plurality of contact pairs at least partially within the plug body, the contact pairs including an inherent asymmetric coupling between individual contacts of one of the contact pairs and other individual contacts of another of the contact pairs. Second asymmetric coupling elements are connected between the individual contacts of one of the contact pairs and the other individual contacts of another of the contact pairs. The second asymmetric coupling elements, when combined with the inherent asymmetric coupling, provide a balanced symmetric coupling between the individual contacts of one of the contact pairs and the other individual contacts of another of the contact pairs. | 07-03-2014 |
20140248807 | COMMUNICATION CONNECTOR - The present invention generally relates to communication connectors and internal components thereof. In one embodiment, the present invention is a communication jack comprising back-rotated plug interface contacts having variable cross-sectional widths. In another embodiment, the present invention is a communication jack having back-rotated plug interface contacts where at least two of the plug interface contacts have a differing beam length. In yet another embodiment, the present invention is a communication jack having back-rotated plug interface contacts where at least two of the plug interface contacts have opposing bends in a deflection zone. | 09-04-2014 |
20150056824 | COMMUNICATION CONNECTOR - Embodiments of the present invention are generally related to communication connectors, and more specifically, to communication connectors such as jacks which are compatible with more than one style of a plug. In one embodiment, the electrical and mechanical design of a jack in accordance with the present invention may extend the usable bandwidth beyond the IEC 60603-7-71 requirement of 1000 MHz to support potential future applications such as, but not limited to, 40GBASE-T. In addition, the jack may be backwards compatible with lower speed BASE-T applications (e.g., 10GBASE-T and/or below) when an RJ45 plug is mated to the jack. | 02-26-2015 |
20150325965 | COMMUNICATION CONNECTOR - The present invention generally relates to communication connectors and internal components thereof. In one embodiment, the present invention is a communication jack comprising hack rotated plug interface contacts having variable cross-sectional widths. In another embodiment, the present invention is a communication jack having back-rotated plug interface contacts where at least two of the plug interface contacts have a differing beam length. In yet another embodiment, the present invention is a communication jack having back-rotated plug interface contacts where at least two of the plug interface contacts have opposing bends in a deflection zone. | 11-12-2015 |
Suresh Babu, Pennington, NJ US
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20130102609 | BIARYL OXYACETIC ACID COMPOUNDS - The present invention provides biaryl oxyacetic acid compounds which may be useful for treating inflammatory disorders, including disorders affecting the respiratory system and skin. The compounds provided include those of the general formula I: | 04-25-2013 |
Suresh Babu, West Chester, PA US
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20130346986 | JOB SCHEDULING PROGRESS BAR - Methods and apparatus, including computer program products, are provided for scheduling batch jobs. In one aspect there is provided a method. The method may receiving, at a progress engine, status information provided by a job scheduler controlling an execution of a plurality of jobs, the status information representative of the plurality of jobs of the batch job; receiving, at the progress engine implemented on at least one processor, reference information representative of past executions of batch jobs; determining, by the progress engine, a completion time for the batch job based on the received status information and the received reference information; and generating, by the progress engine, a page including the determined completion time. Related systems, methods, and articles of manufacture are also disclosed. | 12-26-2013 |
Suresh D. Babu, Plainsboro, NJ US
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20080200445 | Heterocyclic aspartyl protease inhibitors - Disclosed are compounds of the formula I | 08-21-2008 |
20100152138 | CYCLIC AMINE BACE-1 INHIBITORS HAVING A BENZAMIDE SUBSTITUENT - Disclosed are compounds of the formula | 06-17-2010 |
20120231017 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 09-13-2012 |
20120231018 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 09-13-2012 |
20120276118 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 11-01-2012 |
Suresh D. Babu, Pennington, NJ US
Patent application number | Description | Published |
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20090258868 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 10-15-2009 |
20090306047 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 12-10-2009 |
20110218194 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 09-08-2011 |
20130004518 | CYCLIC AMINE BACE-1 INHIBITORS HAVING A BENZAMIDE SUBSTITUENT - Disclosed are compounds of the formula | 01-03-2013 |
20130018066 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 01-17-2013 |
20140057910 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 02-27-2014 |
20140128361 | CYCLIC AMIDE BACE-1 INHIBITORS HAVING A BENZAMIDE SUBSTITUENT - Disclosed are compounds of the formula | 05-08-2014 |
20150105354 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 04-16-2015 |
Suresh P. Babu, Willow Springs, IL US
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20150175414 | CO-CONVERSION OF CARBONACEOUS MATERIAL AND BIOMASS - A method for producing a product includes providing a first feed including a biomass into a reactor, providing a second feed including a carbonaceous material into the reactor, and providing a third feed including carbon dioxide into the reactor. The first feed, the second feed, and the third feed react in the reactor with reaction conditions sufficient to: a) gasify the biomass, b) dry reform the carbonaceous materials with the carbon dioxide, and c) produce the product. A conversion system and a reactor are also provided. | 06-25-2015 |
Suresh R. Babu, Superior Township, MI US
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20110098267 | TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS - The invention relates to a topical composition and a method for treating psoriasis. The topical composition comprises one or more compound that inhibits the production of IL-12 and IL-23. | 04-28-2011 |
20130172333 | FORMULATION AND DOSING OF HSP90 INHIBITORY COMPOUNDS - Provided is a pharmaceutical composition comprising a pharmaceutically acceptable organic solvent, a pharmaceutically acceptable surfactant, and a compound according to the following formula: wherein the variables are defined herein. Optionally, the pharmaceutical composition further comprises a co-solvent. Also provided is a method of using the pharmaceutical composition disclosed herein for the treatment of a patient in need thereof. | 07-04-2013 |
20150150851 | FORMULATION AND DOSING OF HSP90 INHIBITORY COMPOUNDS - Provided is a pharmaceutical composition comprising a pharmaceutically acceptable organic solvent, a pharmaceutically acceptable surfactant, and a compound according to the following formula: wherein the variables are defined herein. Optionally, the pharmaceutical composition further comprises a co-solvent. Also provided is a method of using the pharmaceutical composition disclosed herein for the treatment of a patient in need thereof. | 06-04-2015 |
Surrendra Chitti Babu, New Lenox, IL US
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20130187460 | Active Patch Panel - An active patch panel uses small form factor plus (SFP+) connectivity with a plurality of channels extending between first and second faces of the panel. The channels connect ports on the opposing faces of the panel and are provided with additional electronic elements, such as an equalizer, a clock data recovery element, and a pre-emphasis element. A controller can be connected to the plurality of channels to provide instructions for simultaneous equalization and pre-emphasis of a plurality of cable assemblies in the same channel. | 07-25-2013 |
Suryadevara V. Babu, Potsdam, NY US
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20090176371 | Method For The Preferential Polishing Of Silicon Nitride Versus Silicon Oxide - The present invention provides a method of removing silicon nitride in preference to silicon dioxide by CMP. The method utilizes a polishing slurry that includes colloidal silica abrasive particles dispersed in water and an additive that suppresses the silicon dioxide removal rate but enhances the silicon nitride removal rate. In one embodiment of the invention, the additive is lysine, which is effective at a pH of about 9, or arginine, which is effective at a pH of about 8. In another embodiment of the invention, the additive is lysine mono hydrochloride in combination with picolinic acid, which is effective at a pH of about 8, or arginine in combination with picolinic acid, which is effective at a pH of about 9. | 07-09-2009 |
20100081281 | Abrasive compositions for chemical mechanical polishing and methods for using same - A colloidal dispersion for chemical mechanical polishing comprising: (a) an abrasive component; and (b) from about 0.05% to about 10% by weight of the abrasive component, a water-soluble amphoteric polymer comprising at least one macromolecular chain B and a part A bonded to a single end of the at least one macromolecular chain B, wherein the macromolecular chain B is derived from one or more ethylenically unsaturated monomers having quaternary ammonium groups or inium groups, and wherein the part A is a polymeric or nonpolymeric group comprising at least one anionic group; wherein the dispersion has a pH of between about 1.5 and about 6. The colloidal dispersion is capable of polishing a substrate comprising silicon nitride and silicon oxide with a reverse selectivity ratio of at least about 27, typically at least 50 the reverse selectivity ratio being the ratio of the rate of removal of the silicon nitride to the rate of removal of the silicon oxide. | 04-01-2010 |
20120190200 | Abrasive Free Silicon Chemical Mechanical Planarization - A chemical mechanical planarization method uses a chemical mechanical planarization composition that includes at least one nitrogen containing material and a pH modifying material, absent an abrasive material. The nitrogen containing material may be selected from a particular group of nitrogen containing polymers and corresponding nitrogen containing monomers. The chemical mechanical planarization method and the chemical mechanical planarization composition provide for planarizing a silicon material layer, such as but not limited to a poly-Si layer, in the presence of a silicon containing dielectric material layer, such as but not limited to a silicon oxide layer or a silicon nitride layer, with enhanced efficiency provided by an enhanced removal rate ratio. | 07-26-2012 |
20130122705 | ABRASIVE COMPOSITIONS FOR CHEMICAL POLISHING AND METHODS FOR USING SAME - A colloidal dispersion for chemical mechanical polishing comprising: (a) an abrasive component; and (b) from about 0.05% to about 10% by weight of the abrasive component, a water-soluble amphoteric polymer comprising at least one macromolecular chain B and a part A bonded to a single end of the at least one macromolecular chain B, wherein the macromolecular chain B is derived from one or more ethylenically unsaturated monomers having quaternary ammonium groups or inium groups, and wherein the part A is a polymeric or nonpolymeric group comprising at least one anionic group; wherein the dispersion has a pH of between about 1.5 and about 6. The colloidal dispersion is capable of polishing a substrate comprising silicon nitride and silicon oxide with a reverse selectivity ratio of at least about 27, typically at least 50 the reverse selectivity ratio being the ratio of the rate of removal of the silicon nitride to the rate of removal of the silicon oxide. | 05-16-2013 |
20130209924 | ABRASIVE-FREE PLANARIZATION FOR EUV MASK SUBSTRATES - A process for abrasive-free chemical mechanical planarization of silicon thin film coated EUV mask substrates is disclosed. The process removes bumps and pits on the substrate thereby mitigating reflective errors in the mask. The process employs a two-step polishing procedure, in which the second step is abrasive-free and uses an amine or amine salt as the polishing agent. | 08-15-2013 |
Suryadevara Vijayakumar Babu, Potsdam, NY US
S.v. Babu, Potsdam, NY US
Patent application number | Description | Published |
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20080277378 | Method for Chemical-Mechanical Planarization of Copper - Method for polishing copper by chemical-mechanical planarization. The method of the present invention includes dissolving MoO | 11-13-2008 |
Uma Mahesh Babu, Bradenton, FL US
Patent application number | Description | Published |
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20090289201 | COMBINED VISUAL/FLUORESCENCE ANALYTE DETECTION TEST - The sensitivity of visually read lateral flow immunoassay tests is enhanced by adding a small quantity of fluorescing dye or fluorescing latex bead conjugates to the initial conjugate material. When the visible spectrum test line is visibly present, the test result is observed and recorded. However, in the case where the result is indeterminate, a light of an appropriate spectrum, such as a UV, visible, or infrared spectrum, is cast on the test line to excite and fluoresce the fluorescing latex beads which are bound in the test line in true positive tests to enhance the visible color at the test line. | 11-26-2009 |
20090291508 | NANOPARTICLES IN DIAGNOSTIC TESTS - The present invention includes methods and devices that detect target molecules in a biological sample. The sample analysis device of the present invention includes nanoparticles. In one embodiment, the nanoparticles are directly immobilized on the surface of the sample analysis device. In another embodiment, the nanoparticles are indirectly immobilized on the surface of the sample analysis device by incorporating them in appropriate media and immobilizing the nanoparticles within a matrix. | 11-26-2009 |
20090305290 | LATERAL FLOW NUCLEIC ACID DETECTOR - Point-of-care binding assays include at least one target nucleic acid binding in a multiplex structure with at least one sequence in a partner nucleic acid associated with a label, due to complementary base pairings between at least one sequence in the target nucleic acid and at least one sequence in the partner nucleic acid. The assays overcome the inherent deficiencies of antibody-protein antigen assays. In a preferred embodiment, color tagged nucleic acid sequences are used to bind a complementary target nucleic acid. The tagged nucleic acid sequences are preferably made from deoxyribonucleotides, ribonucleotides, or peptide nucleotides. | 12-10-2009 |
20100015634 | IN SITU LYSIS OF CELLS IN LATERAL FLOW IMMUNOASSAYS - Devices and methods incorporate lysis agents into a point-of-care testing device. The sample is loaded, and then the sample travels until it encounters a lysis agent. The lysis agent is preferably pre-loaded onto the collection device. In a preferred embodiment, the initially lysis agent is localized between the sample application zone and the conjugate zone. The lysis agent is preferably soluble or miscible in the sample transport liquid, and the lysis agent is solubilized and activated upon contact with the sample transport liquid. The sample transport liquid then contains both lysis agent in solution or suspension and sample components in suspension. Any lysis-susceptible components in a sample, then being exposed in suspension to the lysis agent, are themselves lysed in situ. The running buffer then carries the analyte, including any lysis-freed components, to the detection zone. | 01-21-2010 |
20100112725 | METHOD TO INCREASE SPECIFICITY AND/OR ACCURACY OF LATERAL FLOW IMMUNOASSAYS - The present invention includes methods and devices for preventing interfering substances from affecting the accuracy of a lateral flow immunoassay. In preferred embodiments, a test strip includes a capturing zone that includes at least one mobile capturing reagent that separates at least one interfering substance from the analyte. The capturing zone is preferably located upstream of the sample application zone. In some embodiments, the reagent/conjugate zone is also located upstream of the sample application zone. The capturing zone may be located upstream, downstream, or overlapping with the reagent/conjugate zone in these embodiments. In other preferred embodiments, one or more mobile capturing reagents are included in the elution medium/running buffer. In yet other embodiments, the capturing reagent is incorporated into a sample collection device of a sample collection system, preferably separate from the chromatographic test strip. A lysis zone is also included in some preferred embodiments. | 05-06-2010 |
20100297611 | Method and Device For Combined Detection Of Viral And Bacterial Infections - A lateral flow assay detects and differentiates between viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In one preferred embodiment, the bacterial marker is CRP. In another preferred embodiment, the viral marker is MxA. In some embodiments, it is unnecessary to lyse the cells in the sample prior to applying it to the device. | 11-25-2010 |
20110086359 | LATERAL FLOW ASSAYS - Assays and methods including mobile tagged single stranded nucleic acid reagents pre-loaded on an analysis device, which are preferably tagged, but not labeled and are complementary to a strand (preferably the anti-sense strand in double stranded DNA targets) of the target nucleic acid. The assay also includes a running buffer that includes a dye or other detectable label that nonspecifically binds only to double stranded nucleic acids. In addition, the analysis device includes a detection zone including one or more test zones that have an immobilized tag that binds to the tag on the mobile nucleic acid reagent. | 04-14-2011 |
20110136258 | Multiplanar Lateral Flow Assay with Sample Compressor - A sample compressor applies pressure to a sample collector and a sample application zone of a test strip to transfer a sample from the sample collector and a binding partner of an analyte to the sample application zone in a lateral flow device. At least one of the binding partners of the analyte is not located on the test strip prior to use of the lateral flow device. The test strip may be a universal test strip with no molecule that specifically binds the analyte is located on the test strip. The sample compressor may be a universal sample compressor also with no molecule that specifically binds the analyte on the sample compressor. The lateral flow device may also include one or more enhancement elements, where the enhancement elements bind to the analyte sandwich to increase a detection signal in the test zone. | 06-09-2011 |
20120258469 | Methods And Devices For Using Mucolytic Agents Including N-Acetyl Cysteine (NAC) - Devices and methods incorporate mucolytic agents into a point-of-care testing device. The sample is loaded, and then the sample travels until it encounters one or more lysis agents and/or mucolytic agents. The mucolytic agent is preferably pre-loaded onto the collection device. In a preferred embodiment, the mucolytic agent is localized between the sample application zone and the conjugate zone. In embodiments with a sample compressor, one or more mucolytic agents may be pre-loaded and dried on the sample compressor, the sample collector, in various locations on the test strip, or in the running buffer. | 10-11-2012 |
20120264133 | LATERAL FLOW NUCLEIC ACID DETECTOR - Point-of-care binding assays include at least one target nucleic acid binding in a multiplex structure with at least one sequence in a partner nucleic acid associated with a label, due to complementary base pairings between at least one sequence in the target nucleic acid and at least one sequence in the partner nucleic acid. The assays overcome the inherent deficiencies of antibody-protein antigen assays. In a preferred embodiment, color tagged nucleic acid sequences are used to bind a complementary target nucleic acid. The tagged nucleic acid sequences are preferably made from deoxyribonucleotides, ribonucleotides, or peptide nucleotides. | 10-18-2012 |
20130017559 | Lateral Flow Assays With Time Delayed Components - A lateral flow device may include one or more enhancement elements, where the enhancement elements bind to the analyte sandwich to increase a detection signal in the test zone. In preferred embodiments, some or all of the enhancement elements are encapsulated. | 01-17-2013 |
20130130367 | Method And Device For Combined Detection Of Viral And Bacterial Infections - A lateral flow assay detects and differentiates between viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In one preferred embodiment, the bacterial marker is CRP. In another preferred embodiment, the viral marker is MxA. In some embodiments, it is unnecessary to lyse the cells in the sample prior to applying it to the device. | 05-23-2013 |
20130189709 | Multiplanar Lateral Flow Assay with Sample Compressor - A sample compressor applies pressure to a sample collector and a sample application zone of a test strip to transfer a sample from the sample collector and a binding partner of an analyte to the sample application zone in a lateral flow device. At least one of the binding partners of the analyte is not located on the test strip prior to use of the lateral flow device. The test strip may be a universal test strip with no molecule that specifically binds the analyte is located on the test strip. The sample compressor may be a universal sample compressor also with no molecule that specifically binds the analyte on the sample compressor. The lateral flow device may also include one or more enhancement elements, where the enhancement elements bind to the analyte sandwich to increase a detection signal in the test zone. | 07-25-2013 |
20130196310 | Method and Device for Combined Detection of Viral and Bacterial Infections - A lateral flow assay is capable of detecting and differentiating viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In some preferred embodiments, bimodal methods and devices determine if an infection is bacterial and/or viral. A dual use two strip sample analysis device includes a first lateral flow chromatographic test strip to detect MxA and a low level of C-reactive protein and a second lateral flow chromatographic test strip to detect high levels of C-reactive protein. In some preferred embodiments, the sample is a fingerstick blood sample. | 08-01-2013 |
20130196311 | Method and Device for Combined Detection of Viral and Bacterial Infections - A lateral flow assay is capable of detecting and differentiating viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In some preferred embodiments, bimodal methods and devices determine if an infection is bacterial and/or viral. A dual use two strip sample analysis device includes a first lateral flow chromatographic test strip to detect MxA and a low level of C-reactive protein and a second lateral flow chromatographic test strip to detect high levels of C-reactive protein. In some preferred embodiments, the sample is a fingerstick blood sample. | 08-01-2013 |
20130210025 | Lateral Flow Assays - Assays and methods including mobile tagged single stranded nucleic acid reagents pre-loaded on an analysis device, which are preferably tagged, but not labeled and are complementary to a strand (preferably the anti-sense strand in double stranded DNA targets) of the target nucleic acid. The assay also includes a running buffer that includes a dye or other detectable label that nonspecifically binds only to double stranded nucleic acids. In addition, the analysis device includes a detection zone including one or more test zones that have an immobilized tag that binds to the tag on the mobile nucleic acid reagent. | 08-15-2013 |
20130230846 | Multiplanar Lateral Flow Assay with Diverting Zone - A lateral flow device includes a sample compressor and a test strip comprising a diverting zone. The diverting zone, which may include a barrier and/or a gap or ditch, stops or impedes flow. Flow is reinitiated and diverted into an alternate plane by compression of a sample compressor. Flow returns to the original, lateral plane, at the end of the diverting zone. | 09-05-2013 |
20130295583 | Method to Increase Specificity and/or Accuracy of Lateral Flow Immunoassays - The present invention includes methods and devices for preventing interfering substances from affecting the accuracy of a lateral flow immunoassay. In preferred embodiments, a test strip includes a capturing zone that includes at least one mobile capturing reagent that separates at least one interfering substance from the analyte. The capturing zone is preferably located upstream of the sample application zone. In some embodiments, the reagent/conjugate zone is also located upstream of the sample application zone. The capturing zone may be located upstream, downstream, or overlapping with the reagent/conjugate zone in these embodiments. In other preferred embodiments, one or more mobile capturing reagents are included in the elution medium/running buffer. In yet other embodiments, the capturing reagent is incorporated into a sample collection device of a sample collection system, preferably separate from the chromatographic test strip. A lysis zone is also included in some preferred embodiments. | 11-07-2013 |
20130344565 | Optimization of Expression and Purification of Recombinant Human MxA Protein in E. Coli - Full length MxA constructs and truncated MxA constructs produce human MxA protein in | 12-26-2013 |
20140199710 | MULTIPLANAR LATERAL FLOW ASSAY WITH SAMPLE COMPRESSOR - A sample compressor applies pressure to a sample collector and a sample application zone of a test strip to transfer a sample from the sample collector and a binding partner of an analyte to the sample application zone in a lateral flow device. At least one of the binding partners of the analyte is not located on the test strip prior to use of the lateral flow device. The test strip may be a universal test strip with no molecule that specifically binds the analyte is located on the test strip. The sample compressor may be a universal sample compressor also with no molecule that specifically binds the analyte on the sample compressor. The lateral flow device may also include one or more enhancement elements, where the enhancement elements bind to the analyte sandwich to increase a detection signal in the test zone. | 07-17-2014 |
20150099666 | Method And Device For Combined Detection Of Viral And Bacterial Infections - A lateral flow assay detects and differentiates between viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In one preferred embodiment, the bacterial marker is CRP. In another preferred embodiment, the viral marker is MxA. In some embodiments, it is unnecessary to lyse the cells in the sample prior to applying it to the device. | 04-09-2015 |
20150273026 | Clinical Applications for Recombinant Human MxA Protein - Full length MxA constructs and truncated MxA constructs produce human MxA protein in | 10-01-2015 |
20150323527 | Methods and Devices for Using Mucolytic Agents Including N-Acetyl Cysteine (NAC) - Devices and methods incorporate mucolytic agents into a point-of-care testing device. The sample is loaded, and then the sample travels until it encounters one or more lysis agents and/or mucolytic agents. The mucolytic agent is preferably pre-loaded onto the collection device. In a preferred embodiment, the mucolytic agent is localized between the sample application zone and the conjugate zone. In embodiments with a sample compressor, one or more mucolytic agents may be pre-loaded and dried on the sample compressor, the sample collector, in various locations on the test strip, or in the running buffer. | 11-12-2015 |
20160084832 | Method and Device for Combined Detection of Viral and Bacterial Infections - A lateral flow assay is capable of detecting and differentiating viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In some preferred embodiments, bimodal methods and devices determine if an infection is bacterial and/or viral. A dual use two strip sample analysis device includes a first lateral flow chromatographic test strip to detect MxA and a low level of C-reactive protein and a second lateral flow chromatographic test strip to detect high levels of C-reactive protein. In some preferred embodiments, the sample is a fingerstick blood sample. | 03-24-2016 |
Yarlagadda S. Babu, Durham, NC US
Patent application number | Description | Published |
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20120142617 | ANTIVIRAL THERAPEUTIC AGENTS - The invention provides compounds of Formula I: | 06-07-2012 |
20120149662 | Heterocyclic Compounds as Janus Kinase Inhibitors - The invention provides compounds of formula (I): | 06-14-2012 |
20120149691 | Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors - The invention provides compounds of formula I: | 06-14-2012 |
20120213735 | THERAPEUTIC FUROPYRIMIDINES AND THIENOPYRIMIDINES - The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents. | 08-23-2012 |
Yarlagadda Sudhakara Babu, Birmingham, AL US
Patent application number | Description | Published |
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20120059057 | ANTIVIRAL TREATMENTS - The invention provides unit dosage forms, kits, and methods useful for treating viral infections. | 03-08-2012 |