Patent application number | Description | Published |
20090012607 | METHOD FOR THE PREPARATION OF TUBE-TYPE POROUS BIODEGRADABLE SCAFFOLD HAVING DOUBLE-LAYERED STRUCTURE FOR VASCULAR GRAFT - Disclosed herein are a tube-type porous scaffold having a double-layered structure for use as an artificial vascular graft and a preparation method thereof. The method comprises (1) dissolving a biodegradable polymer in an organic solvent and mixing the polymer with a porogen so as to provide a polymer/porogen mixture; (2) coating a cylindrical shaft with the polymer/porogen mixture so as to form an inner porous coating layer; (3) preparing a biodegradable polymer gel by dissolving a biodegradable polymer in an organic solvent; (4) spinning down the biodegradable polymer gel in a non-solvent coagulation bath in which the cylindrical shaft having the inner porous coating layer, obtained at step (2), is immersed and rotated to form gel-phase fibers and allowing the gel-phase fibers to wind around the inner porous coating layer of the rotating shaft so as to form an outer polymer fibrous layer; and (5) separating the double-layered porous scaffold, formed on the shaft, from the shaft and removing the organic solvent and the porogen from the scaffold. Since the porous scaffold has a double-layered structure consisting of an inner porous coating layer containing micropores and a gel-phase outer polymer fibrous layer, it has high pore interconnectivity and mechanical strength, which effectively prevents the leakage of blood, and has high cell seeding and proliferation efficiencies, thereby being useful as a tissue-engineered artificial vascular graft. | 01-08-2009 |
20090200537 | PHASE CHANGE MEMORY DEVICE PREVENTING CONTACT LOSS AND METHOD FOR MANUFACTURING THE SAME - A phase change memory device includes a silicon substrate having a phase change cell region. A plurality of phase change cell are formed in the phase change region of the silicon substrate. A contact comprising a first contact and a second contact is formed on each of the phase change cells. A plurality of bit lines are electrically connected to the contacts. A contact plug is formed on the silicon substrate in a region outside of the phase change cell region, and a word line is formed over the silicon substrate and is connected to the contact plug. | 08-13-2009 |
20100028950 | METHOD FOR THE IMMOBILIZATION OF BIOLOGICALLY ACTIVE POLYPEPTIDES BY USING MALTOSE BINDING PROTEIN - The present invention relates to a method for immobilization of a biologically active polypeptide using maltose binding protein (MBP) and a biologically active solid substrate on which a biologically active polypeptide is immobilized by the above method. More particularly, the present invention relates to a method for immobilization of a biologically active polypeptide comprising the following steps; 1) preparing a fusion protein by linking a biologically active polypeptide to carboxyl terminal of maltose binding protein (MBP); and 2) immobilizing the fusion protein on the hydrophobic surface by physical adsorption of amino terminal containing hydrophobic domain exposed on the surface of maltose binding protein on the hydrophobic surface of a solid substrate, and a biologically active solid substrate on which a biologically active polypeptide is immobilized by the said method. | 02-04-2010 |
20100117046 | PHASE CHANGE MEMORY DEVICE HAVING REDUCED PROGRAMMING CURRENT AND METHOD FOR MANUFACTURING THE SAME - A phase change memory device includes a semiconductor substrate having an active region. An insulation layer is formed on the semiconductor substrate grooves and holes are defined in the insulation layer, with the holes being defined under the grooves to expose portions of the active region. Cell switching are elements formed in the holes and lower portions of the grooves and a phase change layer formed in upper portions of the grooves over the cell switching elements and on portions of the insulation layer adjacent to the grooves such that the phase change layer has a pore structure. Top electrodes are formed on the phase change layer. | 05-13-2010 |
20100120149 | CELL AGGREGATE-HYDROGEL-POLYMER SCAFFOLD COMPLEX FOR CARTILAGE REGENERATION, METHOD FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME - The present invention relates to a cell aggregate-hydrogel-polymer scaffold complex useful for cartilage regeneration which has a structure in which cell aggregates of differentiated chondrocytes are evenly dispersed in a hydrogel matrix, and the resulting hydrogel matrix is immobilized onto the surface of a polymer scaffold while filling up the pores thereof. Since the cell aggregate-hydrogel-polymer scaffold complex according to the present invention can efficiently induce the regeneration of cartilage tissue similar to natural cartilage and retain high mechanical strength, flexibility, and uniform morphology during the cartilage regeneration, it can be effectively used as a cartilage therapeutic agent for the repair of cartilage defects and injuries. | 05-13-2010 |
20100124570 | HIGHLY RESILIENT COPOLYMER WITH SHAPE RECOVERY FORCE AND FLEXIBILITY AND THE USE THEREOF FOR THE REPAIR OF ARTICULAR CARTILAGE DEFECTS - The present invention relates to a highly resilient (lactide/glycolide)/ε-caprolactone copolymer with good shape recovery force, flexibility, and biodegradability and a use of such copolymer for the repair of articular cartilage defects. The highly resilient (lactide/glycolide)/ε-caprolactone copolymer of the present invention is capable of rapidly and efficiently inducing cartilage regeneration, can be easily deformed and almost completely restored to its original form after deformation. Further, the highly resilient copolymer of the present invention can be safely and conveniently transplanted to a patient by using an arthroscope without causing economic, physical, and mental burden. Thus, the highly resilient copolymer of the present invention can be effectively used as a polymer scaffold for the repair of cartilage defects. | 05-20-2010 |
20100171159 | LAYOUT OF SEMICONDUCTOR DEVICE - A layout of a semiconductor device is disclosed, which forms one transistor in one active region to reduce the number of occurrences of a bridge encountered between neighboring layers, thereby improving characteristics of the semiconductor device. Specifically, the landing plug connected to the bit line contact is reduced in size, so that a process margin of word lines is increased to increase a channel length, thereby reducing the number of occurrences of a bridge encountered between the landing plug and the word line. | 07-08-2010 |
20100302281 | MOBILE DEVICE CAPABLE OF TOUCH-BASED ZOOMING AND CONTROL METHOD THEREOF - A mobile device has a touch sensitive surface such as a touch screen. In a touch-based zooming control method, the mobile device displays target data of a selected content on a screen. While the target data is displayed, the mobile device activates a zoom mode in response to a given gesture or input event. Then, the mobile device receives a touch-based gesture input which starts from a specific point on the target data, and executes a zooming function such as a zoom-in and a zoom-out in response to the received gesture input. Particularly, a continuous zooming control in various zooming rates is possible based on a single touch gesture. A toggling-based zooming control is also possible. A bitmap image is used for a rapid real-time display of the target data. | 12-02-2010 |
20100327401 | FUSE OF SEMICONDUCTOR DEVICE - The present invention relates to a fuse for a semiconductor device, and discloses the technique capable of preventing fuse damage, which might occur during a fuse blowing step, with reducing area of the fuse occupying the semiconductor device. The present invention includes a common source region, wherein a plurality of fuses are radially arranged about the common source region, and a fuse box wall is formed outside the fuses. | 12-30-2010 |
20110201710 | METHOD FOR PREPARING BIODEGRADABLE POLYMER STEREOCOMPLEXES USING A SUPERCRITICAL FLUID-ORGANIC SOLVENT SYSTEM AND STEREOCOMPLEXES PREPARED BY THE SAME - The present invention relates to methods for preparing biodegradable polymer stereocomplexes using a supercritical fluid-organic solvent system and polymer stereocomplexes prepared by such methods. The method of the present invention involves introducing two types of homopolymers having different stereostructures and a small amount of organic solvent into a reactor, adding a supercritical fluid thereto, followed by applying a specific temperature and pressure to form a polymer stereocomplex having a crystalline structure. According to the method of the present invention, biodegradable polymer stereocomplexes in the form of powder or porous foam having excellent thermal and mechanical stabilities can be prepared in a simple, economical and environmentally-friendly manner in a single process. | 08-18-2011 |
20120122156 | RECOMBINANT PROTEIN OF FIBROBLAST GROWTH FACTOR HAVING ADHESIVE ACTIVITY FOR STEM CELLS AND METHOD FOR CULTURING STEM CELLS USING THE SAME - The present invention relates to a recombinant protein of a fibroblast growth factor (FGF) having an adhesive activity for stem cells and a method for culturing stem cells using the same. More particularly, the present invention relates to a recombinant protein having an adhesive activity for stem cells by fusion of a polypeptide linker at amino terminal of FGF, and a method for culturing stem cells using immobilized FGF comprising: fixing the recombinant protein in a culture vessel with a hydrophobic surface using amino terminal of the polypeptide linker, adhering stem cells on the recombinant protein-fixed culture vessel, and culturing the stem cells. | 05-17-2012 |
20120134965 | METHOD FOR DIFFERENTIATION OF STEM CELLS INTO VASCULAR CELLS AND THE INDUCTION OF ANGIOGENESIS USING THE SAME - The present invention relates to a method for differentiating stem cells into vascular cells by culturing them in the form of a three-dimensional cell cluster and the use of the three-dimensional cell cluster for angiogenesis. Specifically, the present invention teaches a method for differentiating stem cells into vascular cells comprising culturing stem cells by adhering them onto a culture plate with a surface having a hydrophobic property or a culture plate onto which a growth factor is immobilized, wherein the cultured stem cells are later detached from the culture plate as their density increases to form a three-dimensional cell cluster and grown in the form of a three-dimensional cell cluster while differentiating into vascular cells. Also disclosed is the use of a three-dimensional cell cluster composed of the vascular cells differentiated from stem cells by the above method as a cell therapy agent for angiogenesis. | 05-31-2012 |
20120289618 | PREPARATION METHOD OF CLAY/POLYMER COMPOSITE USING SUPERCRITICAL FLUID-ORGANIC SOLVENT SYSTEM - The present invention relates to a method for preparing a clay/polymer composite having a predetermined form such as powder or porous foam with an enhanced thermal and mechanical stability using a simple, economical and eco-friendly supercritical fluid-organic solvent system, and more particularly, to a method for preparing a clay/biodegradable polymer stereoisomeric nanocomposite and a clay/polymer composite prepared by the method thereof. The method of preparing a clay/polymer composite according to the present invention may include (a) introducing a clay, a biodegradable single-phase D-type/L-type stereoisomeric polymer and an organic solvent into a reactor, (b) introducing a supercritical fluid into the reactor to form a stereoisomeric composite, and forming a clay/polymer composite dispersed with the clay on the stereoisomeric composite, and (c) collecting the clay/polymer composite, and the clay/polymer composite of the present invention is a clay/polymer composite prepared by the preparation method. | 11-15-2012 |
20120306057 | METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE - A method for manufacturing a semiconductor device is disclosed. In the method for manufacturing the semiconductor device, a capacitor structure is modified to ensure capacitance of the capacitor, and the height of the capacitor is reduced to prevent defects such as a leaning capacitor or a poor bridge from being generated, such that the fabrication process of semiconductor devices is simplified and therefore the semiconductor devices can be stably manufactured. | 12-06-2012 |
20130035449 | METHOD FOR PREPARING BIODEGRADABLE POLYMER MATERIALS, BIODEGRADABLE POLYMER MATERIALS AND PRODUCT FOR FIXING BONE - Disclosed are a method for preparing biodegradable polymer materials, biodegradable polymer materials, and a product for fixing bone. The method includes a complex preparing step of preparing polylactide stereoisomeric complex by using a polymer having weight-average molecular weight more than 100,000 g/mol; a molding step of compression-molding the complex; a cooling step of cooling the compression-molded complex; and an extruding step of solid state extruding the cooled complex. Biodegradable polymer materials prepared by the method may be applied to a product for fixing bone or spine requiring high strength. Biodegradable polymer materials may have no corrosion in the body, may require no additional operation for removal after healing bones and tissues, and may prevent stress shielding. | 02-07-2013 |
20130285960 | METHOD FOR IMPROVING TOUCH RESPONSE AND AN ELECTRONIC DEVICE THEREOF - A method and an apparatus for processing touch information in an electronic device are provided. The method for processing touch information includes determining one or more regions for performing a touch event corresponding to touch information in the electronic device displayed on a touch screen, and when detecting a first touch, determining whether to process an event of the first touch in an electronic document by considering a first touch point and the one or more regions. | 10-31-2013 |
20130342485 | METHOD FOR IMPROVING TOUCH RECOGNITION AND ELECTRONIC DEVICE THEREOF - A method for recognizing touch information in an electronic device and an electronic device. The method includes, when a touch is detected, determining whether or not a touch input mode for the touch; determining a reference distance in consideration of the touch input mode; and determining an event type corresponding to the touch by comparing a change distance of a touch point related to the touch with the reference distance. | 12-26-2013 |