Patent application number | Description | Published |
20100317643 | JANUS KINASE INHIBITOR COMPOUNDS AND METHODS - The invention provides compounds of Formula I, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, B, D, R | 12-16-2010 |
20120202788 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE - Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R | 08-09-2012 |
20130096104 | IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE - The invention provides compounds of Formulas Ia-Ib, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R | 04-18-2013 |
20130252941 | PYRAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE - The invention provides compounds of Formula I, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R | 09-26-2013 |
20140171408 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE - Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R | 06-19-2014 |
20140206702 | IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE - The invention provides compounds of Formulas Ia-Ib, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R | 07-24-2014 |
Patent application number | Description | Published |
20100292244 | HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR - The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I. Also provided are methods of using the compound of this invention as an AKT protein kinase inhibitor and for the treatment of hyperproliferative diseases such as cancer. | 11-18-2010 |
20110065716 | HYDROXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases, such as cancer. | 03-17-2011 |
20120232055 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: | 09-13-2012 |
20140349997 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: | 11-27-2014 |
20140357644 | HYDROXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula I: | 12-04-2014 |
20150051217 | HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR - The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I: | 02-19-2015 |
20150065522 | THERAPEUTIC COMPOUNDS AND USES THEREOF - The present invention relates to compounds formula (I): | 03-05-2015 |
Patent application number | Description | Published |
20090085919 | SYSTEM AND METHOD OF MAPPING SHADER VARIABLES INTO PHYSICAL REGISTERS - The present disclosure includes system and method of mapping shader variables into physical registers. In an embodiment, a graphics processing unit (GPU) and a memory coupled to the GPU are disclosed. The memory includes a processor readable data file that has a register file portion. The register file portion has a rectangular structure including a plurality of data items. At least two of the plurality of data items corresponding to data elements of a shader program. The data elements have different data storage types. | 04-02-2009 |
20090089763 | SHADER COMPILE SYSTEM AND METHOD - The present disclosure includes a shader compiler system and method. In an embodiment, a shader compiler includes a decoder to translate an instruction having a vector representation to a unified instruction representation. The shader compiler also includes an encoder to translate an instruction having a unified instruction representation to a processor executable instruction. | 04-02-2009 |
20110231830 | Loop Transformation for Computer Compiler Optimization - A new computer-compiler architecture includes code analysis processes in which loops present in an intermediate instruction set are transformed into more efficient loops prior to fully executing the intermediate instruction set. The compiler architecture starts by generating the equivalent intermediate instructions for the original high level source code. For each loop in the intermediate instructions, a total cycle cost is calculated using a cycle cost table associated with the compiler. The compiler then generates intermediate code for replacement loops in which all conversion instructions are removed. The cycle costs for these new transformed loops are then compared against the total cycle cost for the original loops. If the total cycle costs exceed the new cycle costs, the compiler will replace the original loops in the intermediate instructions with the new transformed loops prior to generation of final code using the instruction set of the processor. | 09-22-2011 |
20120069029 | INTER-PROCESSOR COMMUNICATION TECHNIQUES IN A MULTIPLE-PROCESSOR COMPUTING PLATFORM - This disclosure describes communication techniques that may be used within a multiple-processor computing platform. The techniques may, in some examples, provide software interfaces that may be used to support message passing within a multiple-processor computing platform that initiates tasks using command queues. The techniques may, in additional examples, provide software interfaces that may be used for shared memory inter-processor communication within a multiple-processor computing platform. In further examples, the techniques may provide a graphics processing unit (GPU) that includes hardware for supporting message passing and/or shared memory communication between the GPU and a host CPU. | 03-22-2012 |
20120069035 | INTER-PROCESSOR COMMUNICATION TECHNIQUES IN A MULTIPLE-PROCESSOR COMPUTING PLATFORM - This disclosure describes communication techniques that may be used within a multiple-processor computing platform. The techniques may, in some examples, provide software interfaces that may be used to support message passing within a multiple-processor computing platform that initiates tasks using command queues. The techniques may, in additional examples, provide software interfaces that may be used for shared memory inter-processor communication within a multiple-processor computing platform. In further examples, the techniques may provide a graphics processing unit (GPU) that includes hardware for supporting message passing and/or shared memory communication between the GPU and a host CPU. | 03-22-2012 |
20120284701 | EFFICIENT CONDITIONAL FLOW CONTROL COMPILATION - In general techniques are described for efficient conditional flow control (CFC) compilation. An apparatus comprising a processor executing a compiler that includes at least one translation module may perform these techniques. The translation module translates a first set of high-level (HL) CFC software to a functionally equivalent but different second set of HL CFC software instructions. The compiler then compiles the first and second sets of high-level CFC software instructions to respective first and second sets of low-level (LL) CFC software instructions. An evaluation module of the compiler evaluates the first and second sets of LL CFC software instructions to determine which of the first and second sets of the low-level CFC software instructions is more efficient as measured in terms of at least one execution metric and outputs the one of the first and second low-level CFC software instructions determined to be most efficient. | 11-08-2012 |
20130191816 | OPTIMIZING TEXTURE COMMANDS FOR GRAPHICS PROCESSING UNIT - Aspects of this disclosure relate to a method of compiling high-level software instructions to generate low-level software instructions. In an example, the method includes identifying, with a computing device, a set of high-level (HL) control flow (CF) instructions having one or more associated texture load instructions, wherein the set of HL CF instructions comprises one or more branches. The method also includes converting, with the computing device, the identified set of HL CF instructions to low-level (LL) instructions having a predicate structure. The method also includes outputting the converted (LL) instructions having the predicate structure. | 07-25-2013 |
Patent application number | Description | Published |
20110112893 | System Identification, Estimation, and Prediction of Advertising-Related Data - In accordance with the invention, a system, method, and apparatus for analyzing advertisement-related data are presented, which may include receiving data related to an aspect of an advertisement and modeling the aspect of the advertisement with a mathematical model. The mathematical model may include a control-signal-related component, a control-signal-independent component, and an error component. Each component may be updated based on at least one of a control signal, the received data, and a previous state of at least one of the components. An updated model may be created based on the updated components. The system, method, and apparatus may also include predicting the aspect of the advertisement using the updated model. Exemplary aspects of and data related to the advertisement may include one or more of the following: a number of impressions, “clicks,” or “conversions” and/or the impression-to-conversion, impression-to-click, or click-to-conversion ratios. | 05-12-2011 |
20120136715 | SYSTEM IDENTIFICATION ESTIMATION AND PREDICTION OF ADVERTISING-RELATED DATA - In accordance with the invention, a system, method, and apparatus for analyzing advertisement-related data are presented, which may include receiving data related to an aspect of an advertisement and modeling the aspect of the advertisement with a mathematical model. The mathematical model may include a control-signal-related component, a control-signal-independent component, and an error component. Each component may be updated based on at least one of a control signal, the received data, and a previous state of at least one of the components. An updated model may be created based on the updated components. The system, method, and apparatus may also include predicting the aspect of the advertisement using the updated model. Exemplary aspects of and data related to the advertisement may include one or more of the following: a number of impressions, “clicks,” or “conversions” and/or the impression-to-conversion, impression-to-click, or click-to-conversion ratios. | 05-31-2012 |
20140006143 | SYSTEM IDENTIFICATION, ESTIMATION, AND PREDICTION OF ADVERTISING-RELATED DATA | 01-02-2014 |
20140180789 | SYSTEM IDENTIFICATION, ESTIMATION, AND PREDICTION OF ADVERTISING-RELATED DATA - In accordance with the invention, a system, method, and apparatus for analyzing advertisement-related data are presented, which may include receiving data related to an aspect of an advertisement and modeling the aspect of the advertisement with a mathematical model. The mathematical model may include a control-signal-related component, a control-signal-independent component, and an error component. Each component may be updated based on at least one of a control signal, the received data, and a previous state of at least one of the components. An updated model may be created base on the updated components. The system, method, and apparatus may also include predicting the aspect of the advertisement using the updated model. Exemplary aspects of and data related to the advertisement may include one or more of the following: a number of impressions, “clicks,” or “conversions” and/or the impression-to-conversion, impression-to-click, or click-to-conversion ratios. | 06-26-2014 |
Patent application number | Description | Published |
20090047669 | DNA recombination junction detection - The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide. | 02-19-2009 |
20100173310 | MICROCHIP LARGE-VOLUME PCR WITH INTEGRATED REAL-TIME CE DETECTION - A microfluidic device is provided with appropriate integrated structures to conduct large volume PCR and end-point or real-time capillary electrophoresis detection The microfluidic device includes a substrate having an amplification chamber of a volume of nucleic acid, wells disposed on the substrate, flow channels connecting the wells and the chamber in the substrate to allow for solution flow through the chamber, and one or more separation channels provided in the substrate and connected to the chamber for separating and detecting a fraction of the amplified nucleic acid The chamber, the flow channels, and the one or more separation channels are configured such that the hydrodynamic flow resistance of the chambers and the flow channels combined is at least 10Λ3 times smaller than the hydrodynamic flow resistance in the one or more separation channels The microfluidic device can achieve a very high sensitivity in detection while being highly cost effective | 07-08-2010 |
20100200402 | PRESSURE MANIFOLD TO EQUALIZE PRESSURE IN INTEGRATION PCR-CE MICROFLUIDIC DEVICES - A device is presented that includes a chip having a plurality of wells that are optionally connected by capillary channels, and a manifold member configured to be disposed over the chip for equalizing pressure over the wells and capillary channels. | 08-12-2010 |
20110151577 | DISPOSABLE DEVICE FOR AUTOMATED BIOLOGICAL SAMPLE PREPARATION - A device and a process for preparing biological test samples are presented. The device has a disposable device with a connection mechanism for connecting to a closed sonication tube together with a filter capture unit to capture samples and to handle the samples without requiring additional tubes. With the device and/or method, samples are sonicated in the closed sonication tube that prevents aerosol contamination. | 06-23-2011 |
20120244534 | CLOSED-SYSTEM MULTI-STAGE NUCLEIC ACID AMPLIFICATION REACTIONS - The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers. | 09-27-2012 |
20130065774 | DNA RECOMBINATION JUNCTION DETECTION - The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide. | 03-14-2013 |
20140248624 | DNA RECOMBINATION JUNCTION DETECTION - The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide. | 09-04-2014 |
Patent application number | Description | Published |
20100267049 | DIAGNOSTIC DEVICES AND RELATED METHODS - Devices, systems, and methods for detecting the presence of one or more analytes in a sample are described. In some variations, a test strip may be used to detect and/or analyze one or more analytes in a sample. In certain variations, a test strip configured to receive a sample for detection of an analyte therein may comprise a substrate and a coating on a portion of the substrate, the coating comprising a combination of a first analyte capture agent configured to bind to a first analyte and a second analyte capture agent configured to bind to a second analyte that is different from the first analyte. | 10-21-2010 |
20110076781 | EXPANDING THE DYNAMIC RANGE OF A TEST STRIP - The present invention provides a test strip with an expanded dynamic range for performing an assay to determine the presence of, or measure the quantity of, an analyte in a sample. It also provides methods for determining the presence of, or measuring the quantity of, an analyte in a sample, and for detecting a prozone sample. | 03-31-2011 |
20110177600 | PROTEIN PRODUCTION USING EUKARYOTIC CELL LINES - The subject invention provides a site-specific integration system and methods for generating eukaryotic cells lines for protein production. The provided system includes a first site-specifically integrating target vector and a second site-specifically integrating donor vector comprising a gene of interest. Also provided are mammalian cell lines produced by the subject methods and systems, as well as kits that include the subject systems. | 07-21-2011 |
Patent application number | Description | Published |
20090263485 | Targeted hollow gold nanostructures and methods of use - Provided are novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors and molecular specific photothermal coupling agents. The nanostructures can be used in laser-induced phototherapy for treatment of cancer and other disorders. The nanostructures can also be used as a sensor that detects molecules. The nanostructures are of particular use in the fields of clinical diagnosis, clinical therapy, clinical treatment, and clinical evaluation of various diseases and disorders, manufacture of compositions for use in the treatment of various diseases and disorders, for use in molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof. The hollow gold nanospheres have a unique combination of spherical shape, small size, and strong, tunable, and narrow surface plasmon resonance absorption covering the entire visible to near IR region. | 10-22-2009 |
20100009338 | Novel gold nanostructures and methods of use - The invention is drawn to novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors, conduits for fluids, and electronic conductors. The nanostructures can be used in microfluidic devices, for transporting fluids between devices and structures in analytical devices, for conducting electrical currents between devices and structure in analytical devices, and for conducting electrical currents between biological molecules and electronic devices, such as bio-microchips. | 01-14-2010 |
20110176130 | LIQUID CORE PHOTONIC CRYSTAL FIBER BIOSENSORS USING SURFACE ENHANCED RAMAN SCATTERING AND METHODS FOR THEIR USE - The invention is drawn to a photonic crystal fiber that can be used with nanoparticles to detect and quantify components in a test sample. The invention further relates to methods of using the photonic crystal fiber for detecting chemical and biological analytes, and in use in optical communications. | 07-21-2011 |
20120045754 | NOVEL GOLD NANOSTRUCTURES AND METHODS OF USE - The invention is drawn to novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors, conduits for fluids, and electronic conductors. The nanostructures can be used in microfluidic devices, for transporting fluids between devices and structures in analytical devices, for conducting electrical currents between devices and structure in analytical devices, and for conducting electrical currents between biological molecules and electronic devices, such as bio-microchips. | 02-23-2012 |
20140012224 | Targeted hollow gold nanostructures and methods of use - Provided are novel nanostructures comprising hollow nanospheres (HGNs) and nanotubes for use as chemical sensors, molecular specific photothermal coupling agents, and photothermal ablation compounds. The nanostructures can be used in electromagnetic radiation-induced phototherapy for treatment of cancer and other disorders. The nanostructures can also be used as a sensor that detects molecules. The nanostructures are of particular use in the fields of clinical diagnosis, clinical therapy, clinical treatment, and clinical evaluation of various diseases and disorders, manufacture of compositions for use in the treatment of various diseases and disorders, for use in molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof. The hollow gold nanospheres have a unique combination of spherical shape, small size, and strong, tunable, and narrow surface plasmon resonance absorption covering the entire visible to near IR region. | 01-09-2014 |
Patent application number | Description | Published |
20100321953 | LIGHT EMITTING DEVICES AND APPLICATIONS THEREOF - In one aspect, the present invention provides light emitting devices, including light fixtures and luminaires. In some embodiments, a light emitting device comprises at least one light source, a lightguide operable to receive light from the at least one light source at a first location on the lightguide, at least one light extraction region optically coupled to the lightguide and a substantially non-scattering region along a portion of the lightguide. | 12-23-2010 |
20110013420 | LIGHT EMITTING DEVICES AND APPLICATIONS THEREOF - In one aspect, the present invention provides light emitting devices, including light fixtures and luminaires. In some embodiments, a light emitting device comprises at least one light source, a lightguide operable to receive light from the at least one light source at a first location on the lightguide, at least one light extraction region optically coupled to the lightguide and a substantially non-scattering region along a portion of the lightguide. | 01-20-2011 |
20120092856 | EXTRUDED WIDE ANGLE LENS FOR USE WITH A LED LIGHT SOURCE - This is directed to a lens for use with a LED light source. The lens can be placed on a top surface of a light fixture to direct light emitted by a LED module at a wide angle relative to the top surface of the fixture. The lens can include an elongated trench in which several LED light sources can be placed in a line such that light emitted within the trench is re-directed by the lens. The lens can include one or more knobs extending over the trench to facilitate diverting emitted light in a more lateral direction, as opposed to vertical direction. In some cases, the lens can be constructed using an extrusion process by which a lens having a constant cross-section allowing for a wide angle radiation pattern is provided. | 04-19-2012 |
Patent application number | Description | Published |
20090097262 | LIGHTING FIXTURE WITH RECESSED BAFFLE TRIM UNIT - A recessed lighting fixture providing illumination from a light source comprising a plurality of light emitting diodes (LEDs) placed within a cavity of a planar surface, such as a ceiling, wall, or shower. The fixture comprises a baffle integrated with a low profile heat sink that is used to draw heat out of the fixture and communicate that heat to a trim ring of the fixture for dissipation of the heat in the room so that higher intensity light sources can be used. Improved grounding of the recessed trim unit to the recessed housing is provided with combination support and grounding springs. One embodiment of the light source is fixed in position while a second embodiment is gimbal mounted for aiming the light produced by the fixture. | 04-16-2009 |
20100061108 | LIGHTING FIXTURE WITH RECESSED BAFFLE TRIM UNIT - A recessed lighting fixture providing illumination from a light source including a plurality of light emitting diodes (LEDs) placed within a cavity of a planar surface, such as a ceiling, wall, or shower. The fixture comprises a baffle integrated with a low profile heat sink that is used to draw heat out of the fixture and communicate that heat to a trim ring of the fixture for dissipation of the heat in the room so that higher intensity light sources can be used. Improved grounding of the recessed trim unit to the recessed housing is provided with combination support and grounding springs. One embodiment of the light source is fixed in position while a second embodiment is gimbal mounted for aiming the light produced by the fixture. | 03-11-2010 |
20100172141 | Shop light fixture - A shop light fixture includes reflector. The reflector is of a planar sheet like configuration bent at a left side and a right side. The reflector has a reflector front side and a reflector rear side. A ballast assembly has a ballast front side and a ballast rear side. The ballast front side is mounted to the reflector front side. A first socket and fourth socket are mounted to the ballast front side. A second socket is mounted to the reflector rear side in alignment with the first socket such that the first socket in cooperation with the second socket can receive a first florescent tube. A third socket is mounted to the reflector rear side, and the third socket is electrically connected to the second socket. The third socket and fourth socket receive a second florescent tube. | 07-08-2010 |
20100259173 | Electronic ballast protection - An electronic ballast powers at least one fluorescent tube or lamp which has a power source; a DC power supply having an input connected to the power source; an oscillator connected to an output of said DC power supply so as to be driven therefrom; a driver means; and a protection means that deactivates the oscillator when the output reaches a predetermined abnormally high voltage. The protection means includes a transformer; a plurality of windings disposed on the transformer, a delegated winding disposed on the transformer. The protection means includes a sample point for sampling voltage. The protection means deactivates the delegated winding disposed on the transformer for the magnetizing the transformer and stopping oscillation when the sample point reaches a predetermined abnormally high voltage. | 10-14-2010 |
Patent application number | Description | Published |
20090197916 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR TREATMENT OF METABOLIC SYNDROME AND RELATED DISORDERS - Compounds, compositions, and methods for inhibiting the onset of metabolic syndrome and treating related disorders in a subject in need of such therapy are disclosed. | 08-06-2009 |
20090270452 | USE OF SOLUBLE EPOXIDE HYDROLASE INHIBITORS IN THE TREATMENT OF SMOOTH MUSCLE DISORDERS - Disclosed herein are compounds, compositions, and methods for enhancing smooth muscle function in a subject by administration of soluble epoxide hydrolase inhibitors and for treating subjects with smooth muscle disorders including erectile dysfunction, overactive bladder, uterine contractions and irritable bowel syndrome. | 10-29-2009 |
20100063583 | USE OF SOLUBLE EPOXIDE HYDROLASE INHIBITORS IN THE TREATMENT OF INFLAMMATORY VASCULAR DISEASES - Disclosed herein are compositions and methods for treating inflammatory vascular diseases. Examples of inflammatory vascular disease include, but are not limited to, in-stent stenosis, coronary arterial diseases (CAD), angina, acute myocardial infarction, acute coronary syndrome, chronic heart failure (CHF), peripheral arterial occlusive diseases (PAOD), critical limb ischemia (CLI), cardiac, kidney, liver and intestinal ischemia, renal failure, cardiac hypertrophy, atherosclerosis, abdominal aortic aneurysm, vasculitis, carotid artery stenosis. | 03-11-2010 |
Patent application number | Description | Published |
20100267955 | SYNTHESIS OF PYRAZINES INCLUDING 2,6-DIAMINOPYRAZINE-1-OXIDE (DAPO) AND 2,6-DIAMINO-3,5-DINITROPYRAZINE-1-OXIDE (LLM-105) - A method for synthesizing a pyrazine-containing material according to one embodiment includes contacting an iminodiacetonitrile derivative with a base and a reagent selected from a group consisting of hydroxylamine, a hydroxylamine salt, an aliphatic primary amine, a secondary amine, an aryl-substituted alkylamine a heteroaryl-substituted alkyl amine, an alcohol, an alkanolamine and an aryl alcoholamine. Additional methods and several reaction products are presented. | 10-21-2010 |
20130263982 | MELT-CASTABLE ENERGETIC COMPOUNDS COMPRISING OXADIAZOLES AND METHODS OF PRODUCTION THEREOF - In one embodiment, a melt-castable energetic material comprises at least one of: 3,5-bis(4-nitro-1,2,5-oxadiazol-3-yl)-1,2,4-oxadiazole (DNFO), and 3-(4-amino-1,2,5-oxadiazol-3-yl)-5-(4-nitro-1,2,5-oxadiazol-3-yl)-1,2,4-oxadiazole (ANFO). In another embodiment, a method for forming a melt-castable energetic material includes reacting 3,5-bis(4-amino-1,2,5-oxadiazol-3-yl)-1,2,4-oxadiazole (DAFO) with oxygen or an oxygen-containing compound to form a mixture of at least: DNFO, and ANFO. | 10-10-2013 |
Patent application number | Description | Published |
20080232171 | Phase change memory with program/verify function - A phase change memory includes a plurality of cells for storing data in the form of respective resistance levels, addressing circuits for addressing cells to be programmed, and the resistance levels are determined from comparison of cell currents of addressed cells with a reference current. A reference generator provides the sense amplifier with the reference current. The reference generator is provided with a reference select circuit to select the reference current from a plurality of verify currents based on program data to be stored in the cell. | 09-25-2008 |
20090091988 | Writing bit alterable memories - A bit alterable memory may include current generators in a periphery outside the main memory core. Current may be generated in the periphery and driven into the core. As a result, the capacitance of the memory cells has a lowered effect. The current may be generated using the chip supply voltage and then mirrored using a pump voltage. In some embodiments, the mirroring may be ratioed at the partition level and multiplied at the plane level. A delay may be provided before applying the currents to the cell to accommodate for transients. | 04-09-2009 |
20090161417 | Two cell per bit phase change memory - A phase change memory array may have a plurality of cells in which a bit is determined by a single cell. In addition, a portion of the array may include a plurality of cells which are combined so that two cells form one bit of memory. One of the combined cells is programmed to the complementary state of the other of the combined cells. Thus, the bit is determined by reading the indicator bit which is correctly programmed and comparing it to the complement cell. As a result, the bit may be very reliable because the read window is twice as wide as that used in a conventional phase change memory which compares the selected bit current to a reference current that is midway between the programmed and unprogrammed states. | 06-25-2009 |
Patent application number | Description | Published |
20110017956 | CONJUGATED POLYMERS WITH CARBONYL SUBSTITUTED THIENO[3,4-B]THIOPHENE UNITS FOR POLYMER SOLAR CELL ACTIVE LAYER MATERIALS - In one embodiment of the present disclosure, a series of conjugated polymers used, among other things, as polymer solar cell or polymer photovoltaic device active layer materials, is provided. In one embodiment, the conjugated polymers have the general structure and formula shown in (I), wherein: R1 and R2 are independently selected from proton, halogens, alkyls, aryls and substituted aryls; Ar is selected from the group consisting of monocyclic, bicyclic and polycyclic arylene, or monocyclic, bicyclic and polycyclic heteroarylene. In another embodiment, the conjugated photovoltaic polymers are comprised of repeated units having the general structure of formula (II), wherein, R1, R2, R3, R4, R5, and R6 are independently selected from proton, alkyls, halogens, aryls, substituted aryls, and other kinds of substituents. Synthesis methods of several polymers of the present disclosure are provided, and absorption spectra and electrochemical cyclic voltammetry data of some polymers, and also the photovoltaic properties of the polymers in this present disclosure are also provided. | 01-27-2011 |
20130123449 | CONJUGATED POLYMERS WITH CARBONYL-SUBSTITUTED THIENO [3,4-B] THIOPHENE UNITS FOR POLYMER SOLAR CELL ACTIVE LAYER MATERIALS - In one embodiment of the present disclosure, a series of conjugated polymers used, among other things, as polymer solar cell or polymer photovoltaic device active layer materials, is provided. In one embodiment, the conjugated polymers have the general structure and formula shown in (I), wherein: R1 and R2 are independently selected from proton, halogens, alkyls, aryls and substituted aryls; Ar is selected from the group consisting of monocyclic, bicyclic and polycyclic arylene, or monocyclic, bicyclic and polycyclic heteroarylene. In another embodiment, the conjugated photovoltaic polymers are comprised of repeated units having the general structure of formula (II), wherein, R1, R2, R3, R4, R5, and R6 are independently selected from proton, alkyls, halogens, aryls, substituted aryls, and other kinds of substituents. Synthesis methods of several polymers of the present disclosure are provided, and absorption spectra and electrochemical cyclic voltammetry data of some polymers, and also the photovoltaic properties of the polymers in this present disclosure are also provided. | 05-16-2013 |
Patent application number | Description | Published |
20090307356 | IP ADDRESS ALLOCATION IN A NETWORK ENVIRONMENT - A network access server (NAS) provides a connection to a user in a data communications network, where the NAS is capable of communicating with a home gateway server (HGS) maintaining a pool of IP addresses for allocation to authorized users associated with the NAS. The NAS includes a first memory for storing an identification of a user, an requester for asking the HGS for an IP address on behalf of the user; and a second memory associated with the first memory for storing the IP address of the user received from the HGS. The NAS may further include a detector for periodically detecting connection of the user to the NAS and a keep-alive sender for periodically informing the HGS that the user is still connected to the NAS, a receiver for receiving periodic queries from the HGS about the status of the user connection to the NAS and a responder responsive to said periodic queries for informing the HOS that the use is still connected to the NAS, and/or a receiver for receiving periodic signals from the user and a forwarder responsive to said receiver for forwarding information to the HGS that the user is still connected to the NAS. A home gateway server (HOS) provides mechanisms to assign an IP address to a user via a NAS, and to monitor the status of the IP address after assignment. | 12-10-2009 |
20140056300 | Method of Multiprotocol Label Switching Encapsulation for United Router Farm Forwarding - A network component for supporting packet forwarding in a United Router Farm (URF), the network component comprising a processor configured to receive a packet, encapsulate the packet using a URF header comprising a URF Layer Two (L2) header that indicates Media Access Control (MAC) addresses of current and next hops, an outer label that indicates a tunnel to a destination node in the URF, and an inner label that indicates an egress port on the destination node, and send the packet to a next hop in the URF after encapsulating the packet. | 02-27-2014 |
20140192645 | Method for Internet Traffic Management Using a Central Traffic Controller - A method for internet traffic management, comprising receiving a request for a path set from an application at a network traffic controller, wherein the request contains an intended traffic destination endpoint, evaluating a plurality of network devices in a network, identifying a plurality of paths usable by the application to transmit traffic from the application to the intended traffic destination endpoint, including the plurality of paths in the path set, and sharing the path set with the application. | 07-10-2014 |
20140280864 | Methods of Representing Software Defined Networking-Based Multiple Layer Network Topology Views - A method for network control, comprising receiving a request for a network view from an application at a Software Defined Network (SDN) controller, creating a network view from a network map, wherein the network map comprises a representation of a plurality of network devices and network paths in a SDN-based multiple layer network, and wherein the network view comprises at least a portion of the devices or paths in the network map, and sharing the network view with the application. | 09-18-2014 |
Patent application number | Description | Published |
20090155274 | HUMAN ANTI-NGF NEUTRALIZING ANTIBODIES AS SELECTIVE NGF PATHWAY INHIBITORS - This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided. | 06-18-2009 |
20100034818 | Human Anti-NGF Neutralizing Antibodies as Selective NGF Pathway Inhibitors - This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided. | 02-11-2010 |
20110040076 | Human Anti-NGF Neutralizing Antibodies as Selective NGF Pathway Inhibitors - This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided. | 02-17-2011 |
20110091476 | Human Anti-NGF Neutralizing Antibodies as Selective NGF Pathway Inhibitors - This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided. | 04-21-2011 |
Patent application number | Description | Published |
20090200682 | VIA IN VIA CIRCUIT BOARD STRUCTURE - Methods, systems, and apparatuses for electrical connections through circuit boards are described. A via-in-via structure in a circuit board provides two electrical signal paths. The circuit board includes a dielectric layer having opposing first and second planar surfaces. A first opening extends through the dielectric layer. An electrically conductive coating coats a surface of the dielectric layer in the first opening. An electrically insulating material substantially fills the first opening. The circuit board includes a first additional dielectric layer attached to the first planar surface, and a second additional dielectric layer attached to the second planar surface. A second opening extends through the first additional dielectric layer, the electrically insulating material filling the first opening, and the second additional dielectric layer. An electrically conductive material coats a surface of the first additional dielectric layer, the electrically insulating material, and the second additional dielectric layer in the second opening. | 08-13-2009 |
20090236724 | IC PACKAGE WITH WIREBOND AND FLIPCHIP INTERCONNECTS ON THE SAME DIE WITH THROUGH WAFER VIA - Integrated circuit dies, integrated circuit packages, and methods for assembling the same are provided. An integrated circuit package includes a substrate, an integrated circuit die, a plurality of electrically conductive bump interconnects, an electrically conductive material, and one or more bond wires. The electrically conductive bump interconnects mount a first surface of the die to a first surface of the substrate. The electrically conductive material forms an electrically conductive path from a first electrically conductive feature on the first surface of the die to a second electrically conductive feature on the second surface of the die. The bond wire couples the second electrically conductive feature to a third electrically conductive feature on the first surface of the substrate. In this manner, flip chip bump interconnects and bond wires are available to interface signals of the die with the substrate. | 09-24-2009 |
Patent application number | Description | Published |
20110026130 | LIGHT COLLECTION APPARATUS, SYSTEM AND METHOD - An optical collector is disclosed which includes an imaging, aplanatic optical element having a front surface with a one-way light admitting portion, a back surface with a reflective portion, and an interior region of refractive material disposed between the front and backs surfaces. | 02-03-2011 |
20110026140 | LIGHT CONCENTRATION APPARATUS, SYSTEMS AND METHODS - An optical device is disclosed including: a non-imaging secondary concentrator having an entry aperture and an exit aperture, and configured to receive light focused by a primary focusing element from a source onto the entry aperture. The non-imaging secondary concentrator includes: a first portion proximal the entry aperture which is rotationally symmetric about an optic axis; and a second portion proximal the exit aperture which is not rotationally symmetric about the optic axis. | 02-03-2011 |
20110260037 | LIGHT CONCENTRATION APPARATUS, SYSTEMS AND METHODS - An optical concentrator is disclosed which includes an imaging, aplanatic optical element having a front surface with a one-way light admitting portion, a back surface with a reflective portion, and an interior region of refractive material disposed between the front and backs surfaces. | 10-27-2011 |
20120111397 | KOHLER HOMOGENIZER FOR SOLAR CONCENTRATOR - An apparatus is disclosed including: an entrance aperture for admitting light from a source; an optical collector configured to receive light admitted through the entrance aperture and concentrate the light onto a receiver element; and an optical homogenizer element configured and arranged to image the entrance aperture onto the receiver element. | 05-10-2012 |
20130170046 | LIGHT COLLECTION APPARATUS, SYSTEM AND METHOD - An optical collector is disclosed which includes an imaging, aplanatic optical element having a front surface with a one-way light admitting portion, a back surface with a reflective portion, and an interior region of refractive material disposed between the front and backs surfaces. | 07-04-2013 |
20130228210 | Low Cost High Efficiency Solar Concentrator With Tracking Receivers - One embodiment of the invention relates to a light concentrator apparatus including a reflector with an open substantially hemispherical reflecting surface characterized by a radius R, and an aperture for admitting light onto the hemispherical reflecting surface. The light concentrator apparatus further includes a movable elongated light collector having a first end located proximal to the reflecting surface; and extending along a longitudinal axis in a direction substantially normal to the reflecting surface to a second end. The light concentrator further includes a tracker configured to move the first end of the collector to points proximal to the reflecting surface. | 09-05-2013 |
20130329308 | LIGHT CONCENTRATION APPARATUS, SYSTEMS AND METHODS - An optical device is disclosed including: a non-imaging secondary concentrator having an entry aperture and an exit aperture, and configured to receive light focused by a primary focusing element from a source onto the entry aperture. The non-imaging secondary concentrator includes: a first portion proximal the entry aperture; and a second portion proximal the exit aperture which is not rotationally symmetric about an optic axis. The optical device further comprises a means for homogenizing the light focused onto the entry aperture of the secondary concentrator. | 12-12-2013 |
Patent application number | Description | Published |
20110109383 | MEMS VARACTORS - MEMS varactors capable of handling large signals and/or achieving a high capacitance tuning range are described. In an exemplary design, a MEMS varactor includes (i) a first bottom plate electrically coupled to a first terminal receiving an input signal, (ii) a second bottom plate electrically coupled to a second terminal receiving a DC voltage, and (iii) a top plate formed over the first and second bottom plates and electrically coupled to a third terminal. The DC voltage causes the top plate to mechanically move and vary the capacitance observed by the input signal. In another exemplary design, a MEMS varactor includes first, second and third plates formed on over one another and electrically coupled to first, second and third terminals, respectively. First and second DC voltages may be applied to the first and third terminals, respectively. An input signal may be passed between the first and second terminals. | 05-12-2011 |
20120056855 | INTERFEROMETRIC DISPLAY DEVICE - This disclosure provides systems, methods, and apparatus including one or more capacitance control layers to decrease the magnitude of an electric field between a movable layer and an electrode. In one aspect, a display device includes an electrode, a movable layer, and a capacitance control layer. At least a portion of the movable layer can be configured to move toward the electrode when a voltage is applied across the electrode and the movable layer and an interferometric cavity can be disposed between the movable layer and the first electrode. The capacitance control layer can be configured to decrease the magnitude of an electric field between the movable layer and the electrode when the voltage is applied across the movable layer and the electrode. | 03-08-2012 |
20130057558 | MECHANICAL LAYER AND METHODS OF MAKING THE SAME - This disclosure provides systems, methods and apparatus for controlling a mechanical layer. In one aspect, an electromechanical systems device includes a substrate and a mechanical layer positioned over the substrate to define a gap. The mechanical layer is movable in the gap between an actuated position and a relaxed position, and includes a mirror layer, a cap layer, and a dielectric layer disposed between the mirror layer and the cap layer. The mechanical layer is configured to have a curvature in a direction away from the substrate when the mechanical layer is in the relaxed position. In some implementations, the mechanical layer can be formed to have a positive stress gradient directed toward the substrate that can direct the curvature of the mechanical layer upward when the sacrificial layer is removed. | 03-07-2013 |
20130100065 | ELECTROMECHANICAL SYSTEMS VARIABLE CAPACITANCE DEVICE - This disclosure provides systems, methods and apparatus for electromechanical systems variable capacitance devices. In one aspect, an electromechanical systems variable capacitance device includes a substrate with a bottom bias electrode on the substrate. A first radio frequency electrode above the bottom bias electrode defines a first air gap. A non-planarized first dielectric layer is between the bottom bias electrode and the first radio frequency electrode. A metal layer above the first radio frequency electrode defines a second air gap. The metal layer includes a top bias electrode and a second radio frequency electrode. | 04-25-2013 |
20130100090 | ELECTROMECHANICAL SYSTEMS VARIABLE CAPACITANCE DEVICE - This disclosure provides systems, methods and apparatus for electromechanical systems variable capacitance devices. In one aspect, an electromechanical systems variable capacitance device includes a substrate with a first metal layer including a first bias electrode overlying the substrate. A member suspended above the first metal layer includes a dielectric beam and a second metal layer including a first radio frequency electrode and a ground electrode. The member and the first metal layer define a first air gap. A third metal layer over the member includes a second bias electrode, and the third metal layer and the member define a second air gap. The member includes a plane of symmetry substantially parallel a plane containing the first bias electrode. | 04-25-2013 |
20130176657 | ELECTROMECHANICAL SYSTEMS VARIABLE CAPACITANCE ASSEMBLY - This disclosure provides systems, methods and apparatus for a variable capacitance apparatus. In one aspect, an apparatus includes a plurality of electromechanical systems varactors connected in parallel. Each of the plurality of electromechanical systems varactors includes a first, a second, and a third metal layer. The first metal layer includes a first bias electrode. The second metal layer is spaced apart from the first metal layer to define a first air gap, and includes a first radio frequency electrode. A third metal layer is spaced apart from the second metal layer to define a second air gap, and includes a second radio frequency electrode and a second bias electrode. The second bias electrode of each of the plurality of electromechanical systems varactors has a different projected area perpendicular to a surface of the second metal layer and onto the surface of the second metal layer. | 07-11-2013 |
20140009862 | MEMS VARACTORS - Tunable MEMS resonators having adjustable resonance frequency and capable of handling large signals are described. In one exemplary design, a tunable MEMS resonator includes (i) a first part having a cavity and a post and (ii) a second part mated to the first part and including a movable layer located under the post. Each part may be covered with a metal layer on the surface facing the other part. The movable plate may be mechanically moved by a DC voltage to vary the resonance frequency of the MEMS resonator. The cavity may have a rectangular or circular shape and may be empty or filled with a dielectric material. The post may be positioned in the middle of the cavity. The movable plate may be attached to the second part (i) via an anchor and operated as a cantilever or (ii) via two anchors and operated as a bridge. | 01-09-2014 |
Patent application number | Description | Published |
20090088418 | 4-SUBSTITUTED QUINUCLIDINE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - The present invention relates to compounds and formulations capable of affecting nicotinic acetylcholine receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the alpha7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems. | 04-02-2009 |
20120029044 | 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided. | 02-02-2012 |
20120088736 | [4-(6-HALO-7-Substituted-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL]- -5-CHLORO-THIOPHEN-2-YL-SULFONYLUREAS and Forms and Methods Related Thereto - The present invention provides novel sulfonylurea compounds of formula (I) and pharmaceutically acceptable derivatives and polymorph and amorphous forms thereof. The compounds in their various forms are effective platelet ADP receptor inhibitors and may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also provides a method for preparing such compounds and forms and for preventing or treating thrombosis and thrombosis related conditions in a mammal comprising the step of administering a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or forms thereof. | 04-12-2012 |
20130059898 | 7-AZONIABICYCLO [2.2.1] HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetyl-choline receptor-mediated diseases, such as pulmonary diseases, are provided. | 03-07-2013 |
20130157989 | 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided. | 06-20-2013 |
20140249195 | 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided | 09-04-2014 |
20140256730 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME - Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used. | 09-11-2014 |
20140378521 | USE OF NK-1 RECEPTOR ANTAGONISTS IN PRURITUS - The invention relates to methods for treating pruritus with an NK-1 receptor antagonist. The invention further relates to pharmaceutical compositions comprising NK-1 receptor antagonist. | 12-25-2014 |
20150057255 | USE OF NK-1 RECEPTOR ANTAGONISTS IN PRURITUS - The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical compositions comprising NK-1 receptor antagonists such as serlopitant. In addition, the invention encompasses treatment of a pruritus-associated condition with serlopitant and an additional antipruritic agent, and the use of serlopitant as a sleep aid, optionally in combination with an additional sleep-aiding agent. | 02-26-2015 |
Patent application number | Description | Published |
20090133141 | ENHANCED POLLENIZER AND METHOD FOR INCREASING SEEDLESS WATERMELON YIELD - An enhanced, diploid pollenizer watermelon plant and method used to maximize the yield of triploid seedless watermelons per area. The enhanced pollenizer watermelon plant of the invention is either a hybrid variety, an open-pollinated variety or a synthetic variety, that exhibits the characteristics of small leaves and fruit with a brittle rind that splits when the fruit is overripe or breaks when relatively small physical forces are applied. In one embodiment, the watermelon plant of the invention is also characterized by extended flowering duration, thereby increasing the number of triploid watermelon flowers that are pollinated and set fruit. The method for producing a seedless watermelon fruit, includes the steps of providing a pollenizer diploid watermelon plant, extending the duration of flowering of the pollenizer plant while reducing the number of such plants needed to pollinate the same number of triploid watermelon plants, and maximizing dispersal of the pollenizer watermelon plant throughout the field of triploid watermelon plants. | 05-21-2009 |
20110185443 | WATERMELON POLLENIZER SP-5 - The present invention provides a novel watermelon variety designated SP-5, and method for pollinating seedless watermelon plants. The present invention also provides methods for producing triploid, seedless watermelon fruit. | 07-28-2011 |
20120222152 | INBRED TETRAPLOID WATERMELON LINE 4XASSS4 - A tetraploid watermelon inbred 4XASSS4 is disclosed. The invention relates to the seeds and plants of tetraploid watermelon inbred 4XASSS4, the methods of propagating the tetraploid inbred 4XASSS4 through seeds and tissue culture. The invention also relates to methods of producing the triploid seedless watermelon seeds and plants by crossing inbred 4XASSS4 with diploid watermelon inbreds, and to the triploid plants produced therefrom. The invention further relates to the methods of developing new tetraploid lines by using tetraploid inbred 4XASSS4 as breeding material, and to tetraploid watermelon seeds and plants produced therefrom. | 08-30-2012 |
20130312139 | Methods and Compositions for the Inhibition of Meristematic Growth on Cucurbit Rootstock - The invention provides methods of inhibiting the growth of a shoot apical meristem of a cucurbit rootstock plant, comprising contacting a shoot apical meristem of the cucurbit rootstock plant with an effective amount of a composition comprising one or more fatty alcohols, thereby inhibiting the growth of the shoot apical meristem of the cucurbit rootstock plant. The present invention further provides methods for preparing and producing cucurbit rootstock plants for grafting and methods for grafting. Additionally provided are cucurbit rootstock plants and plant parts and grafted cucurbit plants produced by the methods of the invention. | 11-21-2013 |
20140096292 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF MERISTEMATIC GROWTH ON CUCURBIT ROOTSTOCK - The invention provides methods of inhibiting the growth of a shoot apical meristem of a cucurbit rootstock plant, comprising contacting a shoot apical meristem of the cucurbit rootstock plant with an effective amount of a composition comprising one or more fatty alcohols, thereby inhibiting the growth of the shoot apical meristem of the cucurbit rootstock plant. The present invention further provides methods for preparing and producing cucurbit rootstock plants for grafting and methods for grafting. Additionally provided are cucurbit rootstock plants and plant parts and grafted cucurbit plants produced by the methods of the invention. | 04-03-2014 |
Patent application number | Description | Published |
20080315436 | SEMICONDUCTOR WAFER THAT SUPPORTS MULTIPLE PACKAGING TECHNIQUES - Methods, systems, and apparatuses for semiconductor wafers and integrated circuit chip packaging techniques are provided. A wafer is fabricated that supports multiple different packaging techniques. The wafer is formed to have a plurality of integrated circuit regions. A first plurality of terminals is formed on a surface of the wafer in a central region of each integrated circuit region. A second plurality of terminals is formed on the surface of the wafer in a peripheral region of each integrated circuit region. For each integrated circuit region, each terminal of the second plurality of terminals is electrically coupled through the wafer to at least one terminal of the first plurality of terminals. The integrated circuit regions can be separated into chips that can be packaged in multiple ways. In an aspect, a wafer may be fabricated that supports wire-bond packaging or wafer level ball grid array (WLBGA) packaging for a common chip/die configuration of the wafer. | 12-25-2008 |
20080317185 | DUAL PHASE LOCKED LOOP (PLL) ARCHITECTURE FOR MULTI-MODE OPERATION IN COMMUNICATION SYSTEMS - The clock generating portion of a communication system includes a low-power, high-jitter phase locked loop (PLL) and a high-power, low-jitter PLL. Control logic within the chip allows for selective switching between the low-power and high-power PLL for receiving the broadcast signals, such as mobile TV signals. The switching may occur in a manner that is dependent on the conditions of the wireless channel and/or the complexity of the modulation scheme being used. The switching may be used to provide an oscillating signal from one or both of the PLLs to a receiver to be used to receive communication signals. The control logic may power off one of the PLLs to save power when not in use. | 12-25-2008 |
20090027561 | MOBILE TV SYSTEM WITH USB INTERFACE - Methods, systems, and apparatuses for enabling mobile TV functionality and universal serial bus (USB) functionality are provided. In an example aspect, a mobile television (TV) system includes a mobile TV receiver module and a universal serial bus (USB) interface. The mobile TV receiver module receives a radio frequency (RF) mobile TV signal that includes TV data, and generates a mobile TV data signal that includes the TV data. The USB interface receives the mobile TV data signal, and generates a USB output data signal that includes the TV data. In an aspect, the mobile TV functionality and USB functionality are provided in an integrated circuit chip. In one example, the mobile TV functionality and USB functionality share at least one power supply. In another example, the mobile TV functionality and USB functionality are powered by respective power supplies that are electrically isolated from each other. In such a chip configuration, the chip may be incorporated in a first device that utilizes the USB functionality of the chip, or in a second device that withholds power from the USB functionality. | 01-29-2009 |
Patent application number | Description | Published |
20100048547 | PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, autoimmune and cardiovascular diseases. | 02-25-2010 |
20100075965 | PI3 KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases. | 03-25-2010 |
20100249126 | PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-30-2010 |
20120225859 | PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-06-2012 |
Patent application number | Description | Published |
20090298806 | FACTOR XA INHIBITORS - The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample. | 12-03-2009 |
20100234352 | FACTOR XA INHIBITORS - The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample. | 09-16-2010 |
20110172187 | BORON-CONTAINING SMALL MOLECULES - This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections. | 07-14-2011 |
20110212918 | BORON-CONTAINING SMALL MOLECULES - This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections. | 09-01-2011 |
20120178733 | FACTOR XA INHIBITORS - The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample. | 07-12-2012 |
Patent application number | Description | Published |
20090148951 | Thyroglobulin quantitation by mass spectrometry - Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | 06-11-2009 |
20120009614 | THYROGLOBULIN QUANTITATION BY MASS SPECTROMETRY - Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | 01-12-2012 |
20130005050 | GLUCAGON DETECTION AND QUANTITATION BY MASS SPECTROMETRY - Methods are described for measuring the amount of glucagon in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying glucagon in a sample. | 01-03-2013 |
20130203099 | THYROGLOBULIN QUANTITATION BY MASS SPECTROMETRY - Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | 08-08-2013 |
20140038219 | THYROGLOBULIN QUANTITATION BY MASS SPECTROMETRY - Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | 02-06-2014 |
20140093899 | THYROGLOBULIN QUANTITATION BY MASS SPECTROSCOPY - Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample. | 04-03-2014 |
Patent application number | Description | Published |
20080302732 | INTEGRATED FLUIDICS DEVICES WITH MAGNETIC SORTING - A fluidic device employs one or more sorting stations for separating target species from other species in a sample. At least one of the sorting stations employs a magnetic field gradient to accomplish separation. In addition, the sorting station is integrated on a single substrate with one or more other modules for processing the sample. For example, the fluidic device may include both a sorting station and a separate trapping station that holds some or all components of the sample for additional processing. The trapping station may be located at a position upstream or downstream from the sorting module. | 12-11-2008 |
20090053799 | TRAPPING MAGNETIC SORTING SYSTEM FOR TARGET SPECIES - A system for sorting and trapping magnetic target species includes a microfluidic trapping module designed to receive and then temporarily hold magnetic particles in place within the module. The magnetic particles flowing into the module are trapped there while the other sample components (non-magnetic) continuously flow through and out of the station, thereby separating and concentrating the species captured on the magnetic particles. The magnetic particles and/or their payloads may be released and separately collected at an outlet after the sample passes through the trapping module. | 02-26-2009 |
20110014600 | Microfluidic Magnetophoretic Device and Methods for Using the Same - A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles. | 01-20-2011 |
20120108470 | MICROFLUIDIC MAGNETOPHORETIC DEVICE AND METHODS FOR USING THE SAME - A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles. | 05-03-2012 |
20120115755 | MICROFLUIDIC MAGNETOPHORETIC DEVICE AND METHODS FOR USING THE SAME - A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles. | 05-10-2012 |
Patent application number | Description | Published |
20110003303 | SHEATH FLOW DEVICES AND METHODS - The invention relates generally to fluid processing and, in particular aspects, processing fluids for detection, selection, trapping and/or sorting of particulate moieties. Sheath flow devices described allow isolation of target species from fluid samples while avoiding non-specific binding of unwanted species to the surfaces of the separation device. Biological fluid processing, detection, sorting or selection of cells, proteins, and nucleic acids is described. The invention finds particular use in diagnostic settings, analyzing a patient's medical condition, monitoring and/or adjusting a therapeutic regimen and producing cell based products. | 01-06-2011 |
20110127222 | TRAPPING MAGNETIC CELL SORTING SYSTEM - A system for sorting and trapping magnetic target species includes a microfluidic trapping chamber designed to receive and then temporarily hold magnetic particles in place within the module. An external magnetic source moves relatives to the fluid chamber as the magnetic particles flow the device in the fluidic medium. The magnetic particles flowing into the module are trapped there while the other sample components (non-magnetic) continuously flow through and out of the station, thereby separating and concentrating the species captured on the magnetic particles. The magnetic particles and/or their payloads may be released and separately collected at an outlet after the sample passes through the trapping module. | 06-02-2011 |
20110137018 | MAGNETIC SEPARATION SYSTEM WITH PRE AND POST PROCESSING MODULES - A system for sorting and trapping magnetic target species includes a microfluidic chamber designed to receive and then temporarily hold magnetic particles in place within the module. A pre-processing module may mix a sample and magnetic particles to cause certain species in the sample to be labeled. The micorfluidic chamber may include a mechanism to move magnetic particles within the chamber. A post-processing module or the microfluidic chamber may be used to separate the labeled species from the magnetic particles by adding a release reagent. The magnetic particles and/or their payloads may be released and separately collected at an outlet of the chamber or the post-processing module. | 06-09-2011 |
20120301883 | SHEATH FLOW DEVICES AND METHODS - The invention relates generally to fluid processing and, in particular aspects, processing fluids for detection, selection, trapping and/or sorting of particulate moieties. Sheath flow devices described allow isolation of target species from fluid samples while avoiding non-specific binding of unwanted species to the surfaces of the separation device. Biological fluid processing, detection, sorting or selection of cells, proteins, and nucleic acids is described. The invention finds particular use in diagnostic settings, analyzing a patient's medical condition, monitoring and/or adjusting a therapeutic regimen and producing cell based products. | 11-29-2012 |
Patent application number | Description | Published |
20110128653 | REDUCING GRAM LOAD CHANGE IN ACTUATOR ARM IN A HARD DISK DRIVE - Swaging a suspension base plate to an actuator arm for a hard disk drive. A portion of material adjacent to a hole in the actuator arm is removed to create an opening to receive material. A flange of the suspension base plate is inserted into the hole in the actuator arm. The suspension base plate is swaged to the actuator arm, wherein the swaging causes material from the suspension base plate to flow into the opening. | 06-02-2011 |
20120140360 | INTEGRATED LEAD SUSPENSION (ILS) FOR USE WITH A DUAL STAGE ACTUATOR (DSA) - Approaches for integrated lead suspension that provides many benefits, such as enabling a dual stage actuator (DSA) to be used with a single layer flex with a reduced amount of crosstalk. An integrated lead suspension comprises a tail end having a plurality of conductive pads positioned thereat. The plurality of conductive pads includes a first and second dual stage actuator (DSA) pad. The first and second DSA pads are electrically coupled to a conductive member by way of conductive vias. The conductive member may be a stainless steel island. The first DSA pad conducts a signal to a first terminal at each of a plurality of dual stage actuators, while a second terminal at each of the plurality of dual stage actuators is connected to ground. | 06-07-2012 |
20120160538 | INTERLEAVED CONDUCTOR STRUCTURE WITH OFFSET TRACES - An interleaved conductor structure for electrically connecting the read/write electronics to a read/write head in a hard disk drive is provided. The interleaved conductor structure may allow for an increased characteristic-impedance range, greater interference shielding and a reduction of signal loss that is contributed by a lossy conductive substrate. The electrical traces may have different widths, be offset, or even wrap around each other at the via connections. | 06-28-2012 |
20120160548 | INTERLEAVED CONDUCTOR STRUCTURE WITH TRACES OF VARYING WIDTH - An interleaved conductor structure for electrically connecting the read/write electronics to a read/write head in a hard disk drive is provided. The interleaved conductor structure may allow for an increased characteristic-impedance range, greater interference shielding and a reduction of signal loss that is contributed by a lossy conductive substrate. The electrical traces may have different widths, be offset, or even wrap around each other at the via connections. | 06-28-2012 |
20120162825 | INTERLEAVED CONDUCTOR STRUCTURE WITH WRAP AROUND TRACES - An interleaved conductor structure for electrically connecting the read/write electronics to a read/write head in a hard disk drive is provided. The interleaved conductor structure may allow for an increased characteristic-impedance range, greater interference shielding and a reduction of signal loss that is contributed by a lossy conductive substrate. The electrical traces may have different widths, be offset, or even wrap around each other at the via connections. | 06-28-2012 |
20130148231 | SUSPENSION ASSEMBLY FORMED WITH A PROTECTIVE STRUCTURE - A magnetic disk drive system that has a suspension assembly that includes a slider having a heating element and a suspension configured with a protective structure that protects the heating element. The heating element of the slider can extend through the suspension to extend from the suspension assembly from a side that is opposite the slider. The protective structure is configured to protect the heating element and to prevent the heating element from contacting the heating element of an adjacent suspension during an event such as a physical shock to the disk drive system. | 06-13-2013 |
Patent application number | Description | Published |
20100138281 | System and method for retail store shelf stock monitoring, predicting, and reporting - A system for retail store shelf stock status monitoring, predicting, and reporting that is capable of monitoring retail store current shelf stock capacity and shelf product freshness at product level, category level, department level, store level, and other product hierarchy levels. It is also capable of intelligently predicting future shelf stock status according to predicted future store sales activities. It uses shelf stock empty index, out-of-stock alert, shelf stock freshness, shelf stock expiration alert, and other shelf stock performance measures to present current shelf status, future shelf status, and past shelf stock performances through interactive store maps and other visual presentation means to optimally deliver retail store shelf stock performance information in real time. The system empowers store clerks, store managers, chain store management, and corporation analysts to monitor, review, and analyze store shelf stock status in real time from anywhere at any time. | 06-03-2010 |
20100205045 | System and method for improving retail store customer loyalty - A system and method for improving and maintaining retail store customer loyalty through providing customers with quality services, timely assistances, and conveniences in all stages of product shopping. The system provides a web parts based collaborative online platform for retailers, product manufacturers, and service providers to share resources, distribute coupons, promote products and services, and communicate with customers. It further provides shopping assistances to help customers selectively receive coupons, redeem coupons online, build shopping lists online, retrieve shopping list and shopping reminders, find product shelf locations, place online orders, and manage budgets and nutrition. The system has the capability to collect customer shopping activity data, automatically analyze customer product purchase preferences, recommend products and services, and deliver relevant coupons and advertisements to customers. | 08-12-2010 |