Close, US
Benjamin W. Close, Brazil, IN US
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20140188002 | INFUSION AND BLOOD COLLECTION DEVICE AND METHOD - An infusion and blood collection device allows clean blood collections into a collection tube via a previously installed angiocatheter without interrupting the administration of intravenous therapies after initial installation. The device optionally includes passive control of the blood collection flow rate to prevent contamination of the collected blood draw with the IV therapy fluid being simultaneously infused through the angiocatheter. A blood collection method uses an infusion and blood collection device to draw a clean blood sample from a patient and into a collection tube via a previously installed angiocatheter without interrupting the administration of intravenous therapies. | 07-03-2014 |
Cameron Close, Munroe Falls, OH US
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20150377076 | Control Methods for Heat Engine Systems Having a Selectively Configurable Working Fluid Circuit - Systems and methods for controlling a heat engine system are provided. One method includes initiating flow of a working fluid through a working fluid circuit having a high pressure side and a low pressure side by controlling a pump to pressurize and circulate the working fluid through the working fluid circuit and determining a configuration of the working fluid circuit by determining which of a plurality of waste heat exchangers and which of a plurality of recuperators to position in the high pressure side of the working fluid circuit. The method also includes determining, based on the determined configuration of the working fluid circuit, for each of a plurality of valves, whether to position each respective valve in an opened position, a closed position, or a partially opened position and actuating each of the plurality of valves to the determined opened position, closed position, or partially opened position. | 12-31-2015 |
Clare E. Close, Henderson, NV US
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20130006208 | PROTECTIVE DIAPERING SYSTEM - A protective diapering system is provided for the prevention of migration and introduction of stool with a male's genital area. The protective diapering system including a diaper having an anterior flap, a posterior flap, and a fenestrated flap disposed between the anterior and posterior flaps. | 01-03-2013 |
20130123733 | ABSORBENT ARTICLE AND A METHOD OF FORMING AND USING - An absorbent article is disclosed which is designed to protect both a wearer's penis and scrotum from any bowel movement waste. The absorbent article includes a liquid-impermeable outer cover with a first absorbent and a second absorbent longitudinally positioned on the outer cover. The first absorbent has a first end and a second end, and the second absorbent has a first end and a second end. The second end of the first absorbent is spaced apart from the first end of the second absorbent. A liquid permeable bodyside liner covers the first absorbent and the second absorbent. The absorbent article further includes a fenestrated flap disposed between the first and second absorbents. The fenestrated flap has a first end which is bonded directly to the outer cover. A method of forming the absorbent article, a method of securing the absorbent article onto a body, and a method of removing the absorbent article from a body are also disclosed. | 05-16-2013 |
Daniel M. Close, Knoxville, TN US
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20130031644 | AUTONOMOUS LUX REPORTER SYSTEM AND METHODS OF USE - Disclosed are systems for expression of an autonomous lux reporter system in a vertebrate cell, such as mammalian or fish cell. In some examples the lux reporter system is operably connected to a pollutant-inducible DNA response element. Also disclosed are transgenic zebrafish, carrying pollution-inducible response elements, and methods of using such zebrafish to monitor pollutants. | 01-31-2013 |
David Close, Austin, TX US
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20100110833 | PRESSURE RELEASE ENCODING SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION - A pressure release encoding system for communicating downhole information through a wellbore to a surface location include a downhole tool with a valve for providing a fluid restriction to fluid passing in the wellbore, a sensor positioned in the wellbore for sensing a downhole condition in the wellbore, a brake cooperative with the valve for moving the valve between at least two positions in timed relation to the downhole condition sensed by the sensor, and a detector positioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore. The system associates position of the valve with pressure transduction. The sensor is an inclination sensor for sensing an angle of inclination of the wellbore. | 05-06-2010 |
20110094799 | PRESSURE RELEASE ENCODING SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION - A pressure release encoding system for communicating downhole information through a wellbore to a surface location include a downhole tool with a valve for providing a fluid restriction to fluid passing in the wellbore, a sensor positioned in the wellbore for sensing a downhole condition in the wellbore, a brake cooperative with the valve for moving the valve between at least two positions in timed relation to the downhole condition sensed by the sensor, and a detector positioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore. The system associates position of the valve with pressure transduction. The sensor is an inclination sensor for sensing an angle of inclination of the wellbore. | 04-28-2011 |
20110169655 | METHOD FOR A PRESSURE RELEASE ENCODING SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION - A method for a pressure release encoding system for communicating downhole information through a wellbore to a surface location includes positioning a valve and a brake in a drilling mud circulation system, initiating flow of drilling mud through the system, sensing flow through the valve and setting the brake at predefined pressure levels, sensing downhole conditions and releasing corresponding percentages of pressure across the valve at time intervals, and determining the downhole conditions at the surface by analyzing those associated time intervals. The method includes activation of the encoding system using drilling mud flow and setting predefined pressure levels, so that the pressure drops in the encoding process are from predefined levels at equilibrium and independent of fluid flow. | 07-14-2011 |
David H. Close, Irvine, CA US
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20120310584 | AUTOMATED AND COORDINATED SIMULATION OF MULTIPLE CONCURRENT USER INTERACTIONS - A method and associated system are provided for testing components of a vehicle entertainment system, comprising: interconnecting, via a network, a server computer comprising media content, and a plurality of user computers comprising software and hardware via which the user can interact with the media content; loading a test agent component onto a first of the user computers; loading a first scenario file comprising a series of user entry events that emulate user entry actions via a user interface device of the first user computer; executing the user entry events of the first scenario file by the test agent to generate system events that would normally be generated by a user operating the first user computer to interact with media server; and responding to the first user computer, by the server computer, to the system events. | 12-06-2012 |
Dennis J. Close, Heath, TX US
Patent application number | Description | Published |
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20090015479 | METHOD AND APPARATUS FOR ALL-POLARIZATION DIRECTION FINDING - Embodiments of the present invention provide a method and apparatus for all-polarization direction finding. The method and apparatus generally include acquiring measurements at least partially corresponding to an emitted signal and generated utilizing a blind signal extraction algorithm, forming an all-polarization cost function utilizing the acquired measurements, and determining an angle of arrival for the emitted signal utilizing the formed all-polarization cost function. Such a configuration enables angles of arrivals to be easily determined for signals having any polarization without using a multiple signal classification (MUSIC) algorithm. | 01-15-2009 |
Devin Close, Los Alamos, NM US
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20120077960 | FLUOROBODIES: INTRINSICALLY FLUORESCENT BINDING LIGANDS - Binding ligands with intrinsic fluorescence (“fluorobodies”), fluorobody libraries, and methods of preparing fluorobodies are provided. In one aspect, the invention provides fluorobodies generated from a highly stable, artificial fluorescent protein, eCGP123 and derivatives thereof. | 03-29-2012 |
Donald R. Close, Fairfax, VA US
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20110135440 | SYSTEM AND METHOD FOR UNSLEEVING TRAYS - A system for unstrapping and unsleeving a tray is provided. The system comprises a tray-transport configured to transport a tray in the system, a strap cutter configured to cut a strap on the tray, a strap-removal portion configured to remove the strap cut by the strap cutter, and an unsleeving station configured to remove a sleeve from the tray. The unsleeving station is configured to remove the sleeve from the tray after the strap-removal portion removes the cut strap. | 06-09-2011 |
20120311840 | ELASTOMERIC FORCE MITIGATING JOINT - The technology disclosed provides a joint for connecting carrier units together so as to dissipate and absorb axial forces experienced by the carrier units. The joint may be comprised of a joint housing and an elastomeric insert. The housing may be comprised of a body portion and a head portion and the head portion may include an annular flange in which the elastomeric insert is configured to be secured. The elastomeric joint is capable of absorbing and dissipating horizontal, rotational, and vertical forces experienced by the carrier units in non-linear travel along a track. | 12-13-2012 |
20140251852 | RIGID TRAY CONTAINER AND METHOD OF USE - Embodiments of this disclosure include a rigid tray container and methods and equipment for using the rigid tray container in batched process operations. In one embodiment, a mass container is sized and dimensioned to receive one or several rigid tray containers. In other embodiments, equipment is configured to lid/unlid, secure, stack, load/unload, and buffer rigid tray containers. In other embodiments, equipment is configured to stack and stage mass containers. In some embodiments, methods are provided for batch processing items. | 09-11-2014 |
20150198218 | ELASTOMERIC FORCE MITIGATING JOINT - The technology disclosed provides a joint for connecting carrier units together so as to dissipate and absorb axial forces experienced by the carrier units. The joint may be comprised of a joint housing and an elastomeric insert. The housing may be comprised of a body portion and a head portion and the head portion may include an annular flange in which the elastomeric insert is configured to be secured. The elastomeric joint is capable of absorbing and dissipating horizontal, rotational, and vertical forces experienced by the carrier units in non-linear travel along a track. | 07-16-2015 |
20150203220 | RIGID TRAY CONTAINER AND METHOD OF USE - Embodiments of this disclosure include a rigid tray container and methods and equipment for using the rigid tray container in batched process operations. In one embodiment, a mass container is sized and dimensioned to receive one or several rigid tray containers. In other embodiments, equipment is configured to lid/unlid, secure, stack, load/unload, and buffer rigid tray containers. In other embodiments, equipment is configured to stack and stage mass containers. In some embodiments, methods are provided for batch processing items. | 07-23-2015 |
Edward R. Close, Jackson, MO US
Patent application number | Description | Published |
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20090060778 | METHOD OF MOLD REMEDIATION - A method for remediation of mold in a building comprising the steps of investigating the building to determine a presence of unwanted mold, sampling said unwanted mold both inside and outside of said building to determine a species of said mold and an indoor to outdoor ratio of mold spores for said species, a spore concentration for said species, and a number of colony forming units for said species, diffusing essential oils into the building for a predetermined period of time, where said predetermined period of time is based on a determination of three measures of said species, ratio of indoor to outdoor mold spores, spore concentration, and number of colony forming units; and directly applying a household cleaner with essential oils to any mold-affected areas. Removal and preventative steps prevent the recurrence of the mold infestation. | 03-05-2009 |
Eric Close, Edgeworth, PA US
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20100191376 | NETWORK ARCHITECTURE FOR REMOTE ROBOT WITH INTERCHANGEABLE TOOLS - Systems, methods and devices for the remote control of a robot which incorporates interchangeable tool heads. Although applicable to many different industries, the core structure of the system includes a robot with a tool head interface for mechanically, electrically and operatively interconnecting a plurality of interchangeable tool heads to perform various work functions. The robot and tool head may include several levels of digital feedback (local, remote and wide area) depending on the application. The systems include a single umbilical cord to send power, air, and communications signals between the robot and a remote computer. Additionally, all communication (including video) is preferably sent in a digital format. Finally, a GUI running on the remote computer automatically queries and identifies all of the various devices on the network and automatically configures its user options to parallel the installed devices. Systems according to the preferred embodiments find particular application in the pipeline arts. For example, interchangeable tool heads may be designed to facilitate inspection, debris clearing, cleaning, relining, lateral cutting after relining, mapping, and various other common pipeline-related tasks. | 07-29-2010 |
Frank Close, Houston, TX US
Patent application number | Description | Published |
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20110232912 | SYSTEM AND METHOD FOR HYDRAULICALLY POWERING A SEAFLOOR PUMP FOR DELIVERING PRODUCED FLUID FROM A SUBSEA WELL - A system and method for hydraulically powering a seafloor pump and thereby delivering produced fluid from a subsea well are provided. The system includes a power fluid source, such as a seawater source, which is located at a seasurface location of a sea, and a hydraulically-driven pump, which is located at a seafloor location. The pump is configured to receive a flow of produced fluid from a subsea well and deliver the produced fluid through a riser to a receiver at a seasurface location. One or more conduits that define a feed passage connect the source and the pump, and the source is configured to receive power fluid and provide a flow of the power fluid via the feed passage of the conduit to the pump. The pump is hydraulically operated by the flow of power fluid and delivers the produced fluid from the pump to the receiver. | 09-29-2011 |
Jacquelyn A. Close, Jackson, MO US
Patent application number | Description | Published |
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20090060778 | METHOD OF MOLD REMEDIATION - A method for remediation of mold in a building comprising the steps of investigating the building to determine a presence of unwanted mold, sampling said unwanted mold both inside and outside of said building to determine a species of said mold and an indoor to outdoor ratio of mold spores for said species, a spore concentration for said species, and a number of colony forming units for said species, diffusing essential oils into the building for a predetermined period of time, where said predetermined period of time is based on a determination of three measures of said species, ratio of indoor to outdoor mold spores, spore concentration, and number of colony forming units; and directly applying a household cleaner with essential oils to any mold-affected areas. Removal and preventative steps prevent the recurrence of the mold infestation. | 03-05-2009 |
James Garth Close, Burnet, TX US
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20130037562 | Spring driven method and apparatus for in-carton display and fronting of merchandise items - A spring alignment mechanism utilizes a guide inserted into the rear of a retail-ready display carton. The guide is inserted below merchandise items, so that a spring-driven rear pull member engages the rear-most merchandise item. The pull member travels on the guide so that as items are removed from the carton, remaining items are pulled forward in the display carton. This system facilitates the use of retail-ready packaging, so that cartons of merchandise items may be placed on a shelf without removing the individual items. | 02-14-2013 |
Jamie Close, Chocolay Township, MI US
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20140142638 | BONE PLATE SYSTEM AND METHOD - A bone plate system for securing a plurality of bones is provided including a plate member, a locking device of the bone plate, and a surgical cable having a trailing end for being connected to the bone plate and a leading end for being advanced around the bones and into the locking device. The surgical cable may be tensioned to approximate the bones, urge the bones together, and seat the bone plate against the bones. The locking device may be reconfigured to a locked configuration to fix the bone plate to the surgical cable. The bone plate further includes a plurality of throughbores for receiving bone anchors that rigidly fix the bone plate to the bones. The bone plate system utilizes the tensile strength of the surgical cable and the rigid fixation between the bone anchors and the bone plate to resist relative movement of the bones. | 05-22-2014 |
Jeffrey Robert Close, Fair Haven, VT US
Patent application number | Description | Published |
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20080209727 | FILLET MACHINING WITHOUT ADAPTIVE PROBING AND PARTS FINISHED THEREBY - A method for finishing a part having excess material includes generating one or more surfaces on a model of the part to be machined, creating a machining tool path drive geometry, using the machine tool path drive geometry and one or more surfaces on the model to be machined to generate machining tool paths on the surfaces; and running tool paths on the part in a fixture. | 09-04-2008 |
Joann Close, Los Altos, CA US
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20110128077 | DIFFERENTIALLY COMPENSATED AMPLIFIER - The invention is directed to an amplifier including an absolute value circuit. The absolute value circuit may be driven by differential potentials and may include a first pair of transistors modulating a tail current of the amplifier when a differential input voltage goes high, and a second pair of transistors modulating the tail current of the amplifier when a differential input voltage goes low. | 06-02-2011 |
20150256170 | CIRCUITS WITH FLOATING BIAS - Apparatus and methods to increase the range of a signal processing circuit. A system uses floating bias circuits coupled to a signal processing circuit to increase the range of power supplies that can be used with the signal processing circuit, while maintaining the components of the signal processing circuit within a breakdown voltage threshold. As the voltage level of the data signal varies, the voltage level of the floating bias circuits varies as well. | 09-10-2015 |
Jocelyn Close, Worcester, MA US
Patent application number | Description | Published |
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20150047423 | EDGE SHARPNESS MEASUREMENT - An edge sharpness measurement apparatus includes a clamp for securing a test medium against a frictional member, and an engagement mechanism for a normal force, such that the normal force directs the test medium against the frictional member with a force based on operational conditions of the test medium. A further engagement mechanism is for a tangential force, in which the engagement mechanism is adapted to increase the tangential force to identify a tangential force sufficient to dispose the frictional member across the test medium. A pivot defines an angle of application of the tangential force relative to the normal force, such that disposing the frictional member across the test medium defines a point of overcoming frictional forces between the test medium and the frictional member. A measurement device, such as a gauge or range on a spring, measures the tangential force sufficient to dispose the frictional member. | 02-19-2015 |
John Close, Brookfield, WI US
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20120027178 | METHODS AND APPARATUS FOR ARCHIVING X-RAY FLUOROSCOPY IMAGES - Methods and apparatus for archiving x-ray fluoroscopy images are provided. One method includes receiving fluoroscopic images from a fluoroscopic imaging system and storing all of the received fluoroscopic images during an image acquisition scan by the fluoroscopic imaging system. The received fluoroscopic images are displayed during the image acquisition scan. | 02-02-2012 |
John J. Close, Seattle, WA US
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20140278926 | SYSTEM AND METHOD FOR ATTRIBUTION OF MOBILE ADVERTISEMENTS RELATED TO MOBILE APPLICATIONS - In various embodiments, the present disclosure relates generally to a mobile advertising attribution system. The system enables the proper attribution of user interaction with mobile advertisement related to a mobile application after the user installs the mobile application. The system causes electronic devices to set cookies with advertisement campaign identifiers for advertisement campaigns including the mobile advertisements. When the mobile application is initially executed, the system receives the advertisement campaign identifiers, which enables advertising networks and the vendor of the mobile application to properly and accurately correlate which mobile advertisements are directly and indirectly responsible for the installation of the mobile application. | 09-18-2014 |
20140278927 | SYSTEM AND METHOD FOR ATTRIBUTION OF MOBILE ADVERTISEMENTS RELATED TO MOBILE APPLICATIONS - In various embodiments, the present disclosure relates generally to a mobile advertising attribution system. The system enables the proper attribution of user interaction with mobile advertisement related to a mobile application after the user installs the mobile application. The system causes electronic devices to set cookies with advertisement campaign identifiers for advertisement campaigns including the mobile advertisements. When the mobile application is initially executed, the system receives the advertisement campaign identifiers, which enables advertising networks and the vendor of the mobile application to properly and accurately correlate which mobile advertisements are directly and indirectly responsible for the installation of the mobile application. | 09-18-2014 |
Josh Close, New York, NY US
Patent application number | Description | Published |
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20150356175 | SYSTEM AND METHOD FOR FINDING AND INVENTORYING DATA FROM MULTIPLE, DISTINCT DATA REPOSITORIES - A system and method of finding and inventorying related data in multiple, distinct tables of a data repository may include storing raw data from multiple, distinct tables in a schema-less design format in a schema-less data repository, where the raw data includes data values and metadata associated with the data values. A first set of data values may be identified from the raw data that matches a search parameter. A first set of metadata associated with the identified first set of data values may be identified. A determination of a second set of metadata related to metadata in the first set of metadata may be made. A second set of data values related to the search parameter may be identified, and an inventory inclusive of metadata that provides an inventory to the identified data values for processing. | 12-10-2015 |
20150379096 | SYSTEM AND METHOD FOR AUTOMATICALLY CONNECTING MULTIPLE, DISTINCT TABLES OF A DATA REPOSITORY - A system and method for automatically establishing connections to tables within a data repository may include establishing a pointer to a data repository inclusive of a plurality of tables. System-level metadata within a data repository, catalog, and tables may be accessed. Connections for the respective tables inclusive of data values and metadata associated with the data values may be automatically created. | 12-31-2015 |
Joshua Close, Blasdell, NY US
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20120305454 | METHOD FOR CAPTURING AND RECYCLING IRON CATALYST USED IN THE PRODUCTION OF HALOALKANE COMPOUNDS - Disclosed is a method for capturing and recycling iron catalyst used in the production of haloalkane compounds and more particularly, to an improved process for the manufacture of the compound 1,1,1,3,3-pentachloropropane (HCC-240fa), in which an electromagnetic separation unit (EMSU) is used to facilitate the reaction. When energized, the EMSU functions to remove all iron particles from the reactor effluent; when de-energized, the iron particles captured by the EMSU can be flushed back into the reactor for re-use in the continued production of HCC-240fa. The present invention is also useful in the manufacturing processes for other haloalkane compounds such as HCC-250 and HCC-360. | 12-06-2012 |
20120310020 | METHOD FOR AVOIDING THE GENERATION OF BY-PRODUCTS DURING THE PRODUCTION OF HALOALKANE COMPOUNDS - Disclosed is a process for the manufacture of haloalkane compounds, and more particularly, to an improved process for the manufacture of the compound 1,1,1,3,3-pentachloropropane (HCC-240fa), which mitigates the formation of by-products. The present invention is also useful in the manufacture of other haloalkane compounds such as HCC-250 and HCC-360. One embodiment of the process comprises a method and system for avoiding the formation of polyvinyl chloride during the production of HCC-240fa from CC1 | 12-06-2012 |
20120310021 | METHOD FOR MITIGATING THE FORMATION OF BY-PRODUCTS DURING THE PRODUCTION OF HALOALKANE COMPOUNDS - Disclosed is a process for the manufacture of haloalkane compounds, and more particularly, an improved process for the manufacture of the compound 1,1,1,3,3-penta-chloropropane (HCC-240fa), which mitigates the formation of by-products from vinyl chloride (CH | 12-06-2012 |
20140221705 | SYNTHESIS OF 1,1,2,3-TETRACHLOROPROPENE - The present invention provides an improved process for producing 1,1,2,3-tetrachloropropene. By using a first reactive distillation column for HCC-250fb dehydrochlorination, and a second reactive distillation column for HCC-240db dehydrochlorination/HCC-1230xf isomerization, the 1,1,2,3-tetrachloropropene manufacturing process can be greatly simplified, resulting in reduced equipment use, energy use, as well as increased productivity. | 08-07-2014 |
20140235907 | METHODS FOR THE DEHYDROCHLORINATION OF 1,1,1,3-TETRACHLOROPROPANE TO 1,1,3-TRICHLOROPROPENE - This invention relates to a method to improve 1,1,3-trichloropropene selectivity in HCC-250fb (1,1,1,3-tetrachloropropane) dehydrochlorination. In normal practice, FeCl | 08-21-2014 |
20140275658 | METHOD TO REDUCE THE FORMATION OF HIGH BOILING COMPOUNDS DURING THE DEHYDROCHLORINATION OF 1,1,1,3-TETRACHLOROPROPANE - This invention relates to a method to improve 1,1,3-trichloropropene (HCC-1240za) and/or 3,3,3-trichloropropene (HCC-1240zf) selectivity in the dehydrochlorination of 1,1,1,3-tetrachloropropane (HCC-250fb). In normal practice, FeCl | 09-18-2014 |
Joshua Close, Franklin, MA US
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20090209566 | Spirocyclic Compounds - The present invention relates to a novel class of substituted spirocyclic compounds, represented by the following structural Formula: I Wherein A, B and D are independently selected from CR | 08-20-2009 |
20090270351 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS - The present invention relates to a novel class of phosphorus derivatives. The phosphorus compounds can be used to treat cancer. The phosphorus compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the phosphorus derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the phosphorus derivatives in vivo. | 10-29-2009 |
20090291965 | Histone Deacetylase Inhibitors With Aryl-Pyrazolyl-Motifs - The present invention relates to a novel class of histone deacetylase inhibitors with aryl-pyrazolyl motifs. The compounds of this invention can be used to treat cancer. The compounds of this invention are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The present invention further provides pharmaceutical compositions comprising the compounds of this invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the compounds of this invention in vivo. | 11-26-2009 |
20130131041 | SPIROCYCLIC COMPOUNDS - The present invention relates to a novel class of substituted spirocyclic compounds. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo. | 05-23-2013 |
20140235641 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS - The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. | 08-21-2014 |
Joshua T. Close, Franklin, MA US
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20120329743 | CYCLOALKYL-FUSED TETRAHYDROQUINOLINES AS CRTH2 RECEPTOR MODULATORS - The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), | 12-27-2012 |
20140128367 | CYCLOALKYL-FUSED TETRAHYDROQUINOLINES AS CRTH2 RECEPTOR MODULATORS - The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R | 05-08-2014 |
Kenneth B. Close, New London, WI US
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20110151196 | Flexible Coform Nonwoven Web - A flexible coform nonwoven web that contains a matrix of meltblown fibers and an absorbent material is provided. The meltblown fibers may constitute from about 2 wt % to about 40 wt % of the coform web. The absorbent material may constitute from about 60 wt % to about 98 wt % of the coform web. The Cup Crush Energy/Thickness ratio of the nonwoven structure is desirably less than about 600. The coform web may be imparted with a three-dimensional texture by, for example, using a three-dimensional forming surface. The coform web is suitable for forming absorbent articles such as wipers and personal care absorbent products. | 06-23-2011 |
20120165770 | Absorbent article with stimulation composite - A stimulation material is partially bonded to a pressure-sensitive adhesive to form a stimulation blend. The stimulation blend, with or without pressure-sensitive adhesive, may be juxtaposed between two substrates to form a stimulation composite. When the pressure-sensitive adhesive is present within the stimulation composite, there are regions of the adhesive that do not contain a significant amount of stimulation material. By arranging regions of stimulation blend with respect to the pressure-sensitive adhesive regions, a pattern defined by the stimulation blend is formed. This pattern may deliver a stimulation effect that is at least as effective as using one-hundred percent stimulation blend within the stimulation composite, it not more effective. The stimulation composite may be cut into countless varieties of pledget shapes for use in personal-care absorbent articles. | 06-28-2012 |
20130309439 | Fibrous Nonwoven Web with Uniform, Directionally-Oriented Projections and a Process and Apparatus for Making the Same - A process and apparatus is used for making a fibrous nonwoven web with uniform, directionally-oriented projections by depositing fibrous material onto a first forming surface with holes positioned above a second forming surface with both forming surfaces traveling at different speeds to one another. As the fibers are deposited onto the first forming surface, a portion of the fibers are drawn down into the holes of the first forming surface forming the projections which contact the second forming surface. Due to the speed differential between the two forming surfaces the projections are uniformly skewed in the same direction. The resultant material is particularly suited for use as a wiping material which can be more abrasive in one direction but which is softer to the touch when wiped in the opposite direction thus making it a dual purpose material. | 11-21-2013 |
Kenneth Bradley Close, New London, WI US
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20110152164 | Wet Wipe Having Improved Cleaning Capabilities - A wet wipe that is formed from a nonwoven structure that comprises a matrix of at least one meltblown fibrous material and at least one secondary fibrous material is disclosed. A weight ratio of the at least one secondary fibrous material to the at least one meltblown fibrous material may be between about 40/60 to about 90/10. Additionally, the nonwoven structure has a first side with a textured surface having a three-dimensional texture that includes a plurality of peaks and valleys and a second side with a substantially planar surface. The nonwoven structure includes about 150 to about 600 wt. % of a liquid solution to prepare a wet wipe. The difference in a cleaning pickup percentage between the first side and the second side of the wet wipe is less than 30%, more desirably less than 20%, and even more desirably less than 15%. | 06-23-2011 |
Leland G. Close, Spartanburg, SC US
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20080268732 | Yarns and fabrics having a wash-durable non-electrically conductive topically applied metal-based finish - Durable non-electrically conductive metal treatments (such as coatings or finishes) for yarns and textile fabrics are provided. Such treatments preferably comprise silver and/or silver ions; however, other metals, such as zinc, iron, copper, nickel, cobalt, aluminum, gold, manganese, magnesium, and the like, may also be present or alternatively utilized. Such a treatment provides, as one example, an antimicrobial fiber and/or textile fabric which remains on the surface and does not permit electrical conductivity over the surface. The treatment is extremely durable on such substrates; after a substantial number of standard launderings and dryings, the treatment does not wear away in any appreciable amount and thus the substrate retains its antimicrobial activity (or other property). | 10-30-2008 |
20130281347 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME - Novel compounds based on diaminostilbene are provided. The compounds conform to the general structures | 10-24-2013 |
Michael K. Close, Black Creek, WI US
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20090173366 | BREAKAWAY KNUCKLE FOR ARM OF A CAR WASH - A breakaway knuckle for an arm of a car wash is disclosed. The knuckle allows the arm of a car wash to receive an impact from a vehicle without breaking and return the arm to its original position automatically. The knuckle preferably comprises a joint having a series of inclined grooves and corresponding balls. The knuckle is spring loaded to actuate the return of the arm to an in-use position after an impact, and the balls roll into the grooves to hold the arm in place. | 07-09-2009 |
Miles A. Close, Lino Lakes, MN US
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20100084045 | STERILE LIQUID TRANSFER PORT - A sterile liquid transfer port system is comprised of an alpha assembly, a beta assembly, and a sterilization docking cover. The transfer port apparatus can also be comprised of (a) an isolation wall; (b) a product suite on a first side of the isolation wall; (c) a filling suite on a second side of the isolation wall; (d) an alpha assembly spanning a port in the isolation wall between the first and second sides of the isolation wall; (e) a product tank; (f) a means for sterilization of the product tank, a conduit, and a beta assembly; (g) the beta assembly configured for connection with the alpha assembly for sterile transfer of a product; (h) a conduit for transferring product from the product suite to the filling suite; and (i) equipment in the filling suite for filling product. | 04-08-2010 |
20110256021 | STERILE LIQUID TRANSFER PORT - A sterilization system for a sterile liquid transfer port system includes an isolation wall having a first and second side, an alpha assembly spanning a port in the isolation wall between the first and second sides of the isolation wall and a beta assembly configured for connection with the alpha assembly from the first side of the isolation wall for sterile transfer of a product. The system further includes a docking cover on the first side of the isolation wall which can mate to the beta assembly during a sterilization process. | 10-20-2011 |
Paul Close, Tigard, OR US
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20120290420 | Secure Payment Terminal - Exemplary embodiments include a payment terminal, with corresponding methods, and computer-readable media, which includes a first interface and a second interface. The first interface receives transaction information from an existing interface of a sales device without modification to the sales device. The first interface also transmits first authorization information to the existing interface without requiring modification to the sales device, thereby enabling the sales device to monitor and authorize a transaction associated with the sales device. The second interface transmits authorization request information associated with the transaction to a payment authorization system. The authorization request information represents the payment information. The second interface receives authorization response information associated with the transaction from the payment authorization system. The first authorization information is based on the authorization response information, and the first authorization information does not include the payment information. | 11-15-2012 |
Paul D. Close, Shoreview, MN US
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20100138737 | UNIFIED MANAGEMENT OF CONTEXTUAL INFORMATION FOR A USER INTERACTION IN AN HTML INTERFACE - A system and method for context management which addresses the above problems while isolating the context management functions from the other functional code found on the server system. The context management system includes a context manager component which stores and retrieves name-value pairs describing the context in which the current request is being processed. In doing so, three types of context data are distinguished: static, dynamic, and transient. The context manager stores context data regarding each of a user's sessions and page flows, and returns context data in response to requests from the server system. Using this context data, the server system can then interact with the user in a manner appropriate to the user's context. | 06-03-2010 |
20140095981 | DYNAMIC CONTEXT-BASED CONTENT GENERATION - A system and method for providing context-appropriate information in a computer-user interaction. A method includes receiving, by a data processing system, a request object from a user in a user session, the request object associated with data requested by the user. The method includes initializing dynamic context data according to the request object and dynamically creating customized content based on the user, the user session, and a page flow of the user in the user session. The method includes sending the customized content to be displayed to the user. | 04-03-2014 |
Richard A. Close, Farmington Hills, MI US
Patent application number | Description | Published |
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20090196432 | Integrated vehicle seat and speaker assembly - An integrated seat speaker includes a cushion, a seat frame defining a first internal air volume, and a speaker enclosure defining a second internal air volume. The second internal air volume is acoustically coupled to the first internal air volume through an air passageway, thus producing a continuous acoustical air volume. An acoustic sealing member is disposed between the enclosure and the frame. The frame includes a closure feature at one end for isolating a portion of the first internal air volume. The cushion includes an outer surface, and the speaker enclosure is enclosed within the seat cushion and at least partially concealed by the outer surface. A method optimizes the acoustical performance of a speaker assembly by acoustically coupling an internal air volume defined by a speaker enclosure to another internal air volume defined by a seat frame to create a continuous acoustical air volume. | 08-06-2009 |
20090310812 | Door Speaker Enclosure with Integral Water Barrier and Hardware Attachment - A door speaker box includes an enclosure member and speaker operatively attached thereto, such that they define an acoustic volume, into which the speaker communicates. The enclosure member and speaker are configured to be installed as a speaker box unit in the vehicle door, such that speaker box unit seals the door against moisture passage into the vehicle interior. A flange integrally formed in the enclosure member extends substantially around a portion thereof and is configured to seal against such moisture passage. A hardware mounting surface may be integrally formed in the enclosure member, and configured to receive and support a door hardware component. The flange may further define and enclose the acoustic volume, and may be configured to seal multiple access holes in the inner panel, such that the door is characterized by an absence of rain paper or other dedicated water barrier. | 12-17-2009 |
20120027222 | Vehicle Audio System Having Door Mounted Speaker Support - A vehicle audio system comprises a loud-speaker, a door assembly including a rigid inner panel and an outer panel joined to the inner panel along a front edge, a rear edge, and a bottom edge. A speaker support defined by a highly rigid panel is configured to receive and support the loud speaker in a speaker mounting opening. The speaker support comprises three sides having mounting points located at each corner such that the speaker support and loud speaker supported thereby, contacts the door assembly at a rigid front edge portion, a rigid bottom edge portion and a front corner defined by the intersection of the two. | 02-02-2012 |
20130211663 | NON-BUSSED VEHICLE AMPLIFIER DIAGNOSTICS - Non-bussed amplifier diagnostics are implemented for a vehicle. The vehicle includes an amplifier that includes a computer processor and a memory unit communicatively coupled to the amplifier. The memory unit stores audio test tones, each of which corresponds to a respective diagnostic test result. The vehicle also includes an input device communicatively coupled to the amplifier via wiring. The input device provides an analog signal indicative of a diagnostic test trigger to the amplifier. The computer processor of the amplifier receives the analog signal and executes a diagnostic test defined by the diagnostic test trigger, selects one of the audio test tones based on results of the diagnostic test, and outputs the selected audio test tone via speakers of the vehicle. | 08-15-2013 |
Ryan Close, Greenville, SC US
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20090220343 | HUB PITCH GEAR REPAIR METHOD - A method for repairing a hub pitch gear assembly. The method includes providing a ring assembly for adjusting a pitch angle of a wind turbine blade having a plurality of gear teeth. A segment of the ring assembly is removed, the segment including at least a portion of at least one gear tooth, to form a repair cavity. A repair segment configured to mate the repair cavity is provided and the repair segment is directed into the repair cavity and fastened in position. A repaired pitch gear assembly and wind turbine are also disclosed. | 09-03-2009 |
20140041474 | OVERLOAD SLIP MECHANISM FOR THE YAW DRIVE ASSEMBLY OF A WIND TURBINE - A yaw drive assembly for a wind turbine has a releasable and re-engageable coupling operably configured between a drive gear that engages with a yaw bearing and the output of a gear assembly that is coupled to a drive motor. The coupling maintains a rotational drive engagement between the gear assembly output and drive gear up to a defined rotational torque, wherein the coupling disengages the gear assembly output from the drive gear. The coupling re-engages the gear assembly output to the drive gear upon the rotational torque decreasing to below the defined rotational torque. | 02-13-2014 |
Ryan Spencer Close, Greenville, SC US
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20100083516 | METHOD AND DEVICE FOR MEASURING GEAR TOOTH WEAR - A method and device for measuring an amount of wear on a flank of a gear tooth is provided. The method includes positioning a template comprising a first template tooth adjacent a gear comprising a first gear tooth. The method also includes adjusting the position of the template in a rotational direction with respect to a known rotational reference point of the gear, adjusting the position of the template in an axial direction with respect to a known axial reference point of the gear, and adjusting the position of the template in a radial direction with respect to a known radial reference point of the gear. The method further includes measuring an extent of a gap between an edge of the first template tooth and an adjacent flank of the first gear tooth, wherein the gap corresponds to the amount of wear on the flank. | 04-08-2010 |
20140003946 | CONE ANGLE INSERT FOR WIND TURBINE ROTOR | 01-02-2014 |
20150135534 | SYSTEM AND METHOD FOR UPTOWER MACHINING OF A WIND TURBINE - A system and method for uptower machining of a wind turbine to accommodate a load control system, such as an Advanced Load Controls (ALC) system is disclosed. The load control system includes a plurality of load control components, such as one or more proximity sensors. The method includes designating a first machining location on a rotor lock plate of the wind turbine; mounting a machining device within the wind turbine proximate to the first machining location; machining the first machining location on the rotor lock plate via the machining device; and, installing the load control system within the wind turbine such that at least one of the load control components is installed proximate to the first machining location. | 05-21-2015 |
20150355044 | System and Method for Protecting Rotary Machines - The present disclosure is directed to a system and method for protecting a rotary machine in a high noise environment. In one embodiment, the method includes a step of measuring a vibration signal during operation of the rotary machine. Another step includes modulating the vibration signal at a desired frequency to generate a modulated signal having a direct current (DC) value. The desired frequency varies as a function of an operational parameter of the rotary machine. The method also includes a step of filtering the modulated signal via one or more low-pass filters. Another step includes comparing an amplitude of the filtered signal to a threshold amplitude for one or more components of the rotary machine. The threshold amplitude is indicative of an imbalance within one or more components of the rotary machine. The rotary machine is then operated based on the comparison so as to protect the rotary machine from damage caused by the imbalance within the one or more components of the rotary machine. | 12-10-2015 |
Shawn Michael Close, Portland, OR US
Patent application number | Description | Published |
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20100020144 | Check Valve Unit For Solid Ink Reservoir System - A check valve unit is provided for a high-speed phase change ink image producing machine between a reservoir for receiving and holding a volume of melted ink from a source and a receiving unit, which may be a printhead system. The check valve unit includes a plurality of ball elements trapped between upper and lower housings defining a like plurality of inlet and discharge passageways. The passageways are configured to optimize flow of melted ink through the unit during charging of the secondary reservoir. The check valve unit is scalable as to size and number of reservoirs for a particular application. The unit further incorporates features that simplify the manufacturing and assembly process while maintaining optimal performance. | 01-28-2010 |
20120133714 | Check Valve Unit For Solid Ink Reservoir System - A check valve unit is provided for a high-speed phase change ink image producing machine between a reservoir for receiving and holding a volume of melted ink from a source and a receiving unit, which may be a printhead system. The check valve unit includes a plurality of ball elements trapped between upper and lower housings defining a like plurality of inlet and discharge passageways. The passageways are configured to optimize flow of melted ink through the unit during charging of the secondary reservoir. The check valve unit is scalable as to size and number of reservoirs for a particular application. The unit further incorporates features that simplify the manufacturing and assembly process while maintaining optimal performance. | 05-31-2012 |
20130286111 | PIVOTABLE INK CARTRIDGE PLATFORM FOR PRINTER DEVICE - A printer device includes a housing ( | 10-31-2013 |
Tyler Close, Menlo Park, CA US
Patent application number | Description | Published |
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20090112720 | Identifying And Displaying Messages Containing An Identifier - In a computerized method of identifying and displaying messages containing an identifier, where the messages are privately stored for restricted access by a user, the identifier of a document displayed in a navigation area result window is identified. In addition, the message store is scanned to identify messages containing the identifier and the messages identified as containing the identifier are displayed in a messaging area window. | 04-30-2009 |
20090113281 | Identifying And Displaying Tags From Identifiers In Privately Stored Messages - In a computerized method of identifying and displaying tags that represent respective identifiers in messages privately stored in a message store for restricted access by a user, at least one document identifier is discovered. The message store is scanned to identify messages containing the at least one document identifier and one or more identifiers in the messages identified as containing the at least one document identifier are identified. In addition, respective tags associated with the one or more identifiers are created and displayed in a tag area. | 04-30-2009 |
Tyler J. Close, Menlo Park, CA US
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20100070593 | VISUALIZING FEATURES OF MESSAGES COMMUNICATED BETWEEN USERS - In a computerized method of visualizing features of messages communicated between a first user and a plurality of other users, a topic is identified and a visualization based upon messages containing at least one of the topic and a resource related to the topic is created. More particularly, the visualization is created to include at least one of user graphical representations and message graphical representations, and a resource graphical representation, such that, a user may easily identify features of the messages. | 03-18-2010 |
20100198871 | INTUITIVE FILE SHARING WITH TRANSPARENT SECURITY - A file sharing system includes authorization-based security to control access to shared files; and a synchronizer which uses the authorization-based security to monitor the shared files for changes and propagating the changes according to sharing relationships. A method for file sharing includes using authorization-based security to control access to a shared file; and monitoring the shared file for changes using a synchronizer which incorporates the authorization-based security to access the shared file. | 08-05-2010 |