Rutherford, GB
Alistair Rutherford, Abingdon GB
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20100105914 | CASPASE INHIBITORS AND USES THEREOF - The present invention provides a compound of formula I: | 04-29-2010 |
20100222318 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 09-02-2010 |
20100310675 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention. | 12-09-2010 |
20110020469 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention. | 01-27-2011 |
20120190699 | PYRIDONES USEFUL AS INHIBITORS OF KINASES - The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing the compounds of the invention and intermediate compounds useful in these processes. | 07-26-2012 |
20130034616 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 02-07-2013 |
20130184259 | PYRIDONES USEFUL AS INHIBITORS OF KINASES - The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing the compounds of the invention and intermediate compounds useful in these processes. | 07-18-2013 |
20130261114 | COMPOUNDS USEFUL AS INHIBITORS OF CHOLINE KINASE - The present invention relates to compounds useful as inhibitors of choline kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 10-03-2013 |
20130281445 | COMPOUNDS USEFUL AS INHIBITORS OF CHOLINE KINASE - The present invention relates to compounds useful as inhibitors of choline kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 10-24-2013 |
20150031661 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 01-29-2015 |
20150051187 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 02-19-2015 |
Alistair Peter Rutherford, Abingdon GB
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20120309963 | 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 12-06-2012 |
20140045812 | 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 02-13-2014 |
Alistair Peter Rutherford, Oxfordshire GB
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20100189773 | 5-CYANO-4- (PYRROLO [2,3] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 07-29-2010 |
Andrew Rutherford, Southampton GB
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20090055367 | SYSTEM AND PROGRAM PRODUCTS FOR PRUNING OBJECTS IN A SERVICE REGISTRY AND REPOSITORY - This invention relates to a service registry and repository system, method and computer program product for accessing objects in an object repository. There is provided a method of managing an object database for objects comprising: receiving an object query; querying the object database using the object query; receiving a hierarchical collection of objects including a root object; and returning only those objects that are within a specific depth of the root object and that do not represent user-defined relationships. The returning step maps the objects from a proprietary object format into a standard object format and optionally the standard object format is the Service Definition Object format (SDO). | 02-26-2009 |
20090055410 | METHOD FOR PRUNING OBJECTS IN A SERVICE REGISTRY AND REPOSITORY - This invention relates to a service registry and repository system, method and computer program product for accessing objects in an object repository. There is provided a method of managing an object database for objects comprising: receiving an object query; querying the object database using the object query; receiving a hierarchical collection of objects including a root object; and returning only those objects that are within a specific depth of the root object and that do not represent user-defined relationships. The returning step maps the objects from a proprietary object format into a standard object format and optionally the standard object format is the Service Definition Object format (SDO). | 02-26-2009 |
Christopher Rutherford, West Yorkshire GB
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20150112751 | ENERGY STORAGE - A method of controlling storage of electrical energy by charging and discharging an energy storage device in response to pricing data indicative of future prices of electrical energy over time and energy losses caused by charging and discharging the energy storage device comprises detecting alternating candidate charging and discharging occasions with respect to the pricing data by selecting a next occurrence of a locally minimum price in the pricing data as a candidate charging occasion or a next occurrence of a locally maximum price in the pricing data as a candidate discharging occasion; validating a candidate charging or discharging occasion if the price difference between that candidate charging or discharging occasion and another later price in the pricing data is at least sufficient to compensate for the energy losses caused by charging and discharging the energy storage device; and charging and discharging the energy storage device at the validated charging and discharging occasions, respectively. | 04-23-2015 |
Christopher Rutherford, Malvern GB
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20090041019 | MULTI-PROTOCOL LABEL SWITCHING - A multi-protocol label switching network or domain ( | 02-12-2009 |
20100037311 | SECURE NETWORK ARCHITECTURE - The present invention provides a star-connected network (C | 02-11-2010 |
20100064133 | SECURE NETWORK ARCHITECTURE - The present invention provides a star-connected network (C | 03-11-2010 |
Christopher Rutherford, Hebden Bridge GB
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20130162650 | METHOD, APPARATUS AND GRAPHICAL USER INTERFACE FOR CONTROLLING POWER - A method of controlling power to a device which consumes energy from an energy network. The network has a renewable energy generator and a mains supply connected thereto to supply energy to the network. The method includes determining energy requirements of the device, and determining a renewable energy component of the supplied energy generated by the renewable energy generator. The method compares the energy requirements of the device with the renewable energy component of the supplied energy, and controls the energy to the device in accordance with the comparison between the energy requirements of the device with the renewable energy component of the supplied energy. | 06-27-2013 |
David Rutherford, Ardrossan GB
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20110190638 | Illumination Apparatus for Use in Examining a Body of Living Tissues - An illumination apparatus for use in examining a body of living tissues, the apparatus comprising a head for contacting the body of living tissues, a light source mounted in the head for illuminating the tissues, and an annular switch disposed around the light source, the annular switch being adapted automatically to permit illumination of the light source at an examination intensity when the head contacts the body at least around an annular contact area on the head corresponding to the annular switch. | 08-04-2011 |
Fraser Rutherford, York GB
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20160071113 | Evidence Assessment Systems and Interactive Methods - A method for assessing evidence includes receiving a user request to summarize an ability of the evidence to satisfy agency requirements of one or more agencies. Each of the one or more agencies has a plurality of evidence requirements categorized into one or more domains of a plurality of pre-defined domains. For each combination of an agency from the one or more agencies and a domain from the plurality of the domains, a visual indicator reflecting the ability of the evidence to satisfy at least one evidence requirement of the agency in the domain is generated. An interactive map comprising the generated visual indicators arranged by agencies and domains is rendered on a display device. The interactive map is configured such that a selection of a visual indicator on the map causes information related to the visual indicator to be rendered on the display device. | 03-10-2016 |
Ian Rutherford, Dundee GB
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20080272251 | Holding device for medical purposes - A holding device for medical purposes having a carrier arm on whose distal end a medical instrument can be secured and having at least one joint for positioning the carrier arm and/or the medical instrument, where the joint can be converted between the position that releases the joint and the position that blocks the joint. The holding device provides simple operation, reliable positionability, and can be cleaned well. The joint comprises at least two joint members that enter into active connection with one another by mutually engaging catching elements, where the catching elements are positioned essentially perpendicular to the longitudinal direction of the carrier arm and are pre-tensed with respect to one another by a spring element, and that in the joint at least one hydraulically or pneumatically spreadable expansion element is positioned by which the joint can be converted into the position that releases the joint. | 11-06-2008 |
Ian Rutherford, Gb-Dundee GB
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20090036738 | Device for creating a free transcutaneous access to an endoscopic operating area - The invention relates to a device for creating a free transcutaneous access to an endoscopic operating area, in particular to a hollow internal body organ, which device has a conical inset that is to be inserted into an incision. A device for creating a transcutaneous access that combines simple construction with good handling qualities for several medical instruments is, according to the invention, characterized in that several medical instruments can be inserted simultaneously into the operating area by way of the conical inset, so that the individual medical instruments are positioned in the conical inset at a secured angle to one another. | 02-05-2009 |
James Ormiston Rutherford, Cambridge GB
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20100184123 | Gas Exchange Detection Method and Device - The invention relates to a gas exchange detection method and device particularly, but not exclusively, for rapid detection of the presence of micro-organisms, the effect of an additional substance upon a micro-organism and/or the rate at which oxygen is consumed, in solutions, aqueous emulsions and/or suspensions. | 07-22-2010 |
Mark Rutherford, Doncaster GB
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20150063539 | X-RAY SCANNING SYSTEM AND METHOD - Systems and methods for scanning an item utilizing an X-ray scanner in order to facilitate a determination of whether the X-ray radiation penetrated through the entirety of the scanned item. Various embodiments comprise a conveying mechanism, an X-ray emitter, a detector, and an X-ray penetration grid (XPG). The XPG may comprise a radiopaque grid that may serve as a reference for determining whether radiation passes through the scanned item, the grid oriented such that the grid members are neither parallel nor perpendicular to the direction of travel. Such orientation may minimize or eliminate “ghosted” radiation signals included in a visual display of the radiation received by the detector. A scanned item may be oriented with the XPG such that radiation emitted by the X-ray emitter that passes through a portion of the scanned item must also pass through the XPG before being received by the detector. | 03-05-2015 |
Mark Rutherford, Yorkshire GB
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20090188384 | APPARATUS, KIT AND METHOD - The invention relates to apparatus, a kit and method for aligning a weapon system ( | 07-30-2009 |
Roger Rutherford, Camberley GB
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20140074680 | Futures Exchange Support of Spot Trading - A computer system associated with spot market trading in a particular subject matter may communicate with a computer system associated with trading in futures contracts or options in futures contracts for the subject matter. The communications may include pricing data for at least one of futures contracts or options in futures contracts for the subject matter, which pricing data may be used for spot market pricing. The communications may also include communications regarding futures hedging of spot trading in the subject matter. | 03-13-2014 |
Stephen Graham Rutherford, Hertfordshire GB
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20080264935 | Platter - A platter for use in a forced air/microwave combination oven, the platter comprising an upper surface and a lower surface and incorporating a plurality of apertures passing through the thickness of the platter; wherein one or both of the surfaces of the platter incorporate a recess substantially surrounding at least one of the apertures. The invention also provides a platter incorporating an indentation shaped to receive an item of cookware, the indentation being positioned to align the cookware with microwave radiation in the oven in use. Additionally, the invention provides a platter incorporating apertures distributed over substantially the entire surface area of the platter, and also a platter comprising a central region substantially devoid of apertures, and one or more apertures at substantially the edge of the platter. Preferably the platter is made of a polymer material, particularly preferably a liquid crystal polymer resin such as DuPont (RTM) Zenite (RTM) 7130. Also provided is a method of cooking using such a platter. | 10-30-2008 |
Stephen Graham Rutherford, Herfordshire GB
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20080223860 | Cookware - An article of cookware for use in an oven, wherein the artiste of cookware comprises a base having an upper surface, wherein at least a first region of the upper surface incorporates a plurality of upward protrusions, and wherein the uppermost regions of said protrusions are substantially coplanar for supporting a food product for cooking. Preferably the upper surface between said protrusions is inclined relative to the uppermost regions of said protrusions. A gutter may be provided around at least part of said first region, arranged such that liquid released from a foodstuff during cooking flows into the gutter. The invention further provides a method of cooking using an oven and such an article of cookware. | 09-18-2008 |
William Rutherford, Hamilton GB
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20110138733 | CONNECTOR FOR CONSTRUCTION ELEMENTS AND METHOD OF CONNECTING - There is herein described a connector system. More particularly, there is herein described a connector ( | 06-16-2011 |
William Rutherford, Wishaw GB
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20110179618 | SUPPORT APPARATUS - A support apparatus for assembling a frame comprising: a first support member for supporting a first frame member; a second support member spaced apart from the first support member for supporting a second frame member and allowing the first and second frame members to be connected by a third frame member; and rotating means for rotating the first and second support members to allow the first and second frame members to be connected by a fourth frame member. | 07-28-2011 |