Goodwin, NC
Barry Goodwin, Cary, NC US
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20140108060 | TRANSGENIC CROP FINANCIAL SYSTEMS AND METHODS - The invention provides systems and methods for determining discounted rates for insurance on and financial products relating to transgenic traited crops as compared to their traditional, non-traited counterparts. Certain methods of the invention involve generating comparison data contrasting the yields of transgenic traited crops to their traditional non-traited counterparts. The distribution of the differences between the transgenic and traditional yields is measured. The degree of correlation between the transgenic yields and the differences between the transgenic and traditional yields is measured to create a novel method for assessing mitigation of abiotic and biotic stresses by transgenic crops. A probability distribution function is fit to a traditional rate structure, and a distribution for the transgenic crop yield is determined. The discounted premium rate is determined from the probability function, and a discount rate factor is determined. | 04-17-2014 |
Bryan James Goodwin, Morrisville, NC US
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20090288181 | Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 11-19-2009 |
20090307785 | Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 12-10-2009 |
20120171690 | Transgenic Animals for Analyzing CYP3A4 Cytochrome P450 Gene Regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 07-05-2012 |
Bryan James Goodwin, Durham, NC US
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20080227864 | Lhr1 Activators as Medicaments - Methods or prevention or treatment of diseases or conditions caused by low plasma apoA-1 levels, the use of LRH1 activators in such methods and methods for identification of compounds useful in such treatment. | 09-18-2008 |
Bryan James Goodwin, Carrborro, NC US
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20100146652 | XENOBIOTIC RELATED INDUCTION OF GENE EXPRESSION - An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals. | 06-10-2010 |
Christopher J. Goodwin, Greenville, NC US
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20090222167 | MULTI-DIRECTION VEHICLE CONTROL SENSING - A vehicle includes a first control configured to operate the vehicle from a first operator position facing a front of the vehicle and a second control configured to operate the vehicle from a second operator position facing a rear of the vehicle. The vehicle further includes a processor configured to monitor for an operator presence in the first operator position or the second operator position and receive a vehicle operating request, wherein the operator presence is monitored independent of receiving the vehicle operating request. The processor is further configured to enable either the first control or the second control and select a vehicle operating parameter associated with the vehicle operating request, wherein the vehicle operating parameter varies according to which control is enabled. | 09-03-2009 |
20130158807 | MULTI-DIRECTION VEHICLE CONTROL SENSING - A vehicle includes a first control configured to operate the vehicle from a first operator position facing a front of the vehicle and a second control configured to operate the vehicle from a second operator position facing a rear of the vehicle. The vehicle further includes a processor configured to monitor for an operator presence in the first operator position or the second operator position and receive a vehicle operating request, wherein the operator presence is monitored independent of receiving the vehicle operating request. The processor is further configured to enable either the first control or the second control and select a vehicle operating parameter associated with the vehicle operating request, wherein the vehicle operating parameter varies according to which control is enabled. | 06-20-2013 |
Edward C. Goodwin, Edenton, NC US
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20100280755 | METHOD, APPARATUS, AND SYSTEM FOR RAPID ASSESSMENT - Systems and devices for assessment of an impact by an event on an environment are disclosed. Processes for automated impact assessment are also disclosed. An impact assessment can be performed in computer-generated environments which include data regarding the environment impacted and data regarding the event impacting the environment. Environment data may be represented as a geospatial layer. | 11-04-2010 |
20130218471 | METHOD, APPARATUS AND SYSTEM FOR RAPID ASSESMENT - Systems and devices for assessment of an impact by an event on an environment are disclosed. Processes for automated impact assessment are also disclosed. An impact assessment can be performed in computer-generated environments which include data regarding the environment impacted and data regarding the event impacting the environment. Environment data may be represented as a geospatial layer. | 08-22-2013 |
Frank Goodwin, Chapel Hill, NC US
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20090101522 | High Temperature Electrochemical Characterization of Molten Metal Corrosion - A system and method for the high temperature in-situ determination of corrosion characteristics of a molten metal on an alloy under study is provided which takes place within an insulated furnace. A graphite crucible provided in the furnace contains an electrolyte formed from a molten salt of a metal halide. A reference electrode formed from the same metal as the electrolyte is immersed in the electrolyte solution in the graphite crucible. A beta-alumina crucible containing a molten metal is also provided within the furnace and preferably within the graphite crucible. A measuring electrode formed from the alloy under study is immersed in the molten metal. Standard electrochemical techniques are used to measure and analyze the electrochemical effects of corrosion of the molten metal on the alloy. | 04-23-2009 |
Jodi Maglich Goodwin, Durham, NC US
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20100105749 | CHEMICAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS - The present invention provides compounds of the formulae (I) and (II), and derivatives thereof, for the treatment of cardiovascular conditions | 04-29-2010 |
Linda Goodwin, Concord, NC US
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20110022420 | SYSTEMS AND METHODS FOR INSURANCE UNDERWRITING - The systems and methods described herein may automate insurance underwriting by integrating information from multiple online databases and creating decision making advice useful to insurance underwriters. One system includes a client, database, and server. The client allows an underwriter to enter applicant information, enter customized risk modifiers, and receive an underwriting decision. The database provides additional applicant information. This information can include one or more of prescription drug history, credit history, motor vehicle records, and geocentric mortality risk. The server obtains the applicant information, calculates the applicant's risk, and makes an underwriting decision. Another system calculates a prescription drug risk for an applicant from pharmacy benefits management data, drug risk category data, and application data. Another system calculates a geocentric mortality risk for an applicant from census data, mortality data, credit information, and application data. Preset external modifiers are added to systems and methods of calculating risk in order to allow the underwriter to customize the risk results. | 01-27-2011 |
20130173283 | SYSTEMS AND METHODS FOR INSURANCE UNDERWRITING - The systems and methods described herein may automate insurance underwriting by integrating information from multiple online databases and creating decision making advice useful to insurance underwriters. One system includes a client, database, and server. The client allows an underwriter to enter applicant information, enter customized risk modifiers, and receive an underwriting decision. The database provides additional applicant information. This information can include one or more of prescription drug history, credit history, motor vehicle records, and geocentric mortality risk. The server obtains the applicant information, calculates the applicant's risk, and makes an underwriting decision. Another system calculates a prescription drug risk for an applicant from pharmacy benefits management data, drug risk category data, and application data. Another system calculates a geocentric mortality risk for an applicant from census data, mortality data, credit information, and application data. Preset external modifiers are added to systems and methods of calculating risk in order to allow the underwriter to customize the risk results. | 07-04-2013 |
Michael Goodwin, Raleigh, NC US
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20090313587 | METHOD AND APPARATUS FOR PROVIDING MOTION ACTIVATED UPDATING OF WEATHER INFORMATION - An approach provides updating of weather information on a mobile device. Motion of a mobile device is detected, wherein the mobile device is configured to execute a weather application for presenting weather information to a user. Update of the weather information is retrieved in response to the detected motion. | 12-17-2009 |
Scott Goodwin, Hillsborough, NC US
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20100183302 | OPTICAL SWITCH - An optical device for switching an optical signal between a first optical path and a second optical path, including a substrate, a first guide forming at least a portion of the first optical path, formed on the substrate, and having a movable portion separated from the substrate, a second guide forming at least a portion of the second optical path and disposed adjacent to the first guide, and means for electro statically bending the movable portion so as to optically couple the first guide to the second guide. | 07-22-2010 |
Scott Goodwin, Chapel Hill, NC US
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20140354443 | METHODS AND SYSTEMS FOR DETECTING RFID TAGS IN A BOREHOLE ENVIRONMENT - Sensor assemblies are deployed in a borehole for a well, such as an oil well or other hydrocarbon recovery well. The sensor assemblies may be coupled to a casing string (e.g., the exterior of the casing), and detect RFID tags or other properties of material (e.g., fluids) in an annulus surrounding the casing string. During cementing or other operations, RFID tags may be used to track fluids. RFID detection circuits may be used to scan at different frequencies, and corresponding results may be compared by various means and processes to determine the presence of RFID tags. | 12-04-2014 |
20140367092 | METHODS AND APPARATUS FOR EVALUATING DOWNHOLE CONDITIONS THROUGH FLUID SENSING - An apparatus and method may operate to mount one or more communication assemblies relative to the exterior of a casing being placed in a borehole. Two communication assemblies can be placed in longitudinally spaced relation to one another along the casing, wherein each communication assembly is configured to obtain excitation responses from electrodes of a fluid sensing component, where the excitation responses vary based on properties of fluids in one or more regions of the annulus surrounding the casing. Additional apparatus, systems, and methods are disclosed. | 12-18-2014 |
Scott Goodwin, Research Triangle Park, NC US
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20140111349 | METHODS AND APPARATUS FOR EVALUATING DOWNHOLE CONDITIONS WITH RFID MEMS SENSORS - A radio frequency identification (RFID) tag can include a die attached to an inductive-capacitive (LC) circuit including a capacitive element coupled to an inductive element. The LC circuit can have a resonant frequency that varies according to properties of fluid proximate the RFID tag. The RFID tag can further include a coating material disposed around the die to form an outer surface of the RFID tag. The coating material may have a thickness over a portion of the LC circuit, to permit a conductivity property of a fluid proximate the outer surface to affect the resonant frequency of the LC circuit such that the resonant frequency shifts to a second resonant frequency. Additional apparatus, systems, and methods are disclosed. | 04-24-2014 |
20140174732 | METHODS AND APPARATUS FOR EVALUATING DOWNHOLE CONDITIONS THROUGH RFID SENSING - An apparatus and method may operate to mount one or more communication assemblies relative to the exterior of a casing being placed in a borehole. Two communication assemblies can be placed in longitudinally spaced relation to one another along the casing, wherein each communication assembly is configured to obtain data from RFID tags in one or more azimuthally oriented regions of the annulus surrounding the casing, and to interrogate RFID tags in a first fluid in the borehole. Additional apparatus, systems, and methods are disclosed. | 06-26-2014 |
20140182845 | TIMELINE FROM SLUMBER TO COLLECTION OF RFID TAGS IN A WELL ENVIRONMENT - Sensor assemblies are deployed in a borehole for a well, such as an oil well or other hydrocarbon recovery well. The sensor assemblies are coupled to a casing string (e.g., the exterior of the casing), and may detect RFID tags or other properties of material (e.g., fluids) in an annulus surrounding the casing string. Limited battery power for the sensor assemblies and for assemblies for communicating sensed data may be a concern, and the sensor assemblies and communication assemblies may therefore operate in different modes of varying power consumption. In certain modes, sensing operations are curtailed (or expanded) depending on particular requirements. In one case, sensor operation is expanded during active portions of a cementing operation, and curtailed prior to and thereafter. Different triggering events may cause the sensor assembly to operate in different modes at different sensing frequencies. | 07-03-2014 |
20140182848 | ALGORITHM FOR ZONAL FAULT DETECTION IN A WELL ENVIRONMENT - A hydrocarbon well (e.g., oil well) may be monitored during to determine whether a fault exists during an operation such as injecting sealant (e.g., cement) into the borehole. RFID tags may be mixed in a wellbore fluid (e.g., drilling mud, cement, etc.), placed into a borehole, and then tracked within the borehole by communication assemblies with RFID sensors. Data may be obtained by interrogating RFID tags in one or more azimuthally oriented regions of an annulus surrounding a casing of the borehole. Fluid distribution in the annulus will be evaluated with respect to azimuthally offset regions of the annulus. | 07-03-2014 |
Scott H. Goodwin, Hillsborogh, NC US
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20140042753 | ENERGY STORAGE RESERVOIR - An energy management system includes an energy storage reservoir and a fluid pump. The reservoir includes a fluid reservoir configured to contain varying quantities of a fluid and to isolate the fluid from the ambient. The fluid reservoir has a top surface, bottom surface, flexible member, and at least one opening for filling or emptying the reservoir. A pressing mass of solid material is positioned above the fluid reservoir with a weight sufficient to press the reservoir and empty the reservoir of fluid when the reservoir opening is open. The pressing mass is supported by the fluid reservoir when the reservoir contains fluid and is closed. The flexible member is disposed around the fluid reservoir to seal the fluid and to facilitate vertical motion of the pressing mass as the reservoir is filled and emptied. The pump supplies fluid to the fluid reservoir via the opening. | 02-13-2014 |
Scott H. Goodwin, Hillsborough, NC US
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20100236644 | Methods of Operating Microvalve Assemblies and Related Structures and Related Devices - A valve assembly may include a main housing and first and second electro-statically actuated valves. The main housing may define at least three chambers, with a first chamber configured to be coupled to a high pressure supply port, a second chamber configured to be coupled to an output port, and a third chamber configured to be coupled to a low pressure exhaust port. The first electro-statically actuated valve may be provided between the first and second chambers, and the first electro-statically actuated valve may allow or substantially block fluid communication between the first chamber and the second chamber responsive to a first electrical signal. The second electro-statically actuated valve may be provided between the second and third chambers, and the second electro-statically actuated valve may allow or substantially block fluid communication between the second chamber and the third chamber responsive to a second electrical signal. Related methods are also discussed. | 09-23-2010 |
20130270967 | METHOD FOR FORMING AN ULTRASONIC TRANSDUCER, AND ASSOCIATED APPARATUS - A method is provided for forming a piezoelectric ultrasonic transducer apparatus having a first electrode deposited on a dielectric layer disposed on a primary substrate. A piezoelectric material is deposited between the first electrode and a second electrode, to form a transducer device. At least the piezoelectric material is patterned such that a portion of the first electrode extends laterally outward therefrom. The primary substrate and the dielectric layer are etched to form a first via extending to the laterally outward portion of the first electrode, and a first conductive material is deposited to substantially fill the first via and form an electrically-conductive engagement with the laterally outward portion of the first electrode. The primary substrate is etched to define a second via extending therethrough, wherein the second via is laterally spaced apart from the first via. An associated method and apparatus are also provided. | 10-17-2013 |
Scott H. Goodwin, Chapel Hill, NC US
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20130200753 | METHODS FOR FORMING A CONNECTION WITH A MICROMACHINED ULTRASONIC TRANSDUCER, AND ASSOCIATED APPARATUSES - A method and associated apparatus directed to a piezoelectric micromachined ultrasonic transducer (pMUT) defining an air-backed cavity are provided. A first via defined by a device substrate and associated dielectric layer, and extending to the first electrode, is substantially filled with a first conductive material. A support member engaged with the device substrate defines a second via extending to the first conductive material. The second via has a second conductive material disposed thereon, forms an electrically-conductive engagement with the first conductive material, and extends outwardly of the second via to be accessible externally to the support member. A connective element extends through a third via defined by a connection support substrate and is in electrically-conductive engagement with the second conductive material, wherein one of the connective element and connection support substrate is bonded to one of the support member and second conductive material by a bonding material engaged therebetween. | 08-08-2013 |
Steven J. Goodwin, Fuquay Varina, NC US
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20110132837 | Method and System for Treating Wastewater - Methods and systems for utilizing biological wastewater treatment processes to remove nutrients from wastewater containing reduced sulfide compounds may include treating the wastewater in an anaerobic zone, an anoxic zone, and an aerobic zone. The wastewater is first treated in the anaerobic zone to uptake residual biodegradable organic material using specialized bacteria known as phosphorus accumulating organisms (“PAOs”) and glycogen accumulating organisms (“GAOs”). After treatment in the anaerobic zone, the wastewater is treated in an anoxic zone to convert nitrates to nitrogen gas and sulfur to sulfates. Following treatment in the anoxic zone, the wastewater is treated in the aerobic zone to oxidize ammonia to nitrate and to complete removal of phosphorus. After treatment in the aerobic zone, the wastewater may be treated in other zones, or may be delivered to a liquid-solids treatment stage. | 06-09-2011 |