Sutton, GB
Alan Sutton, Salisbury GB
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20150086653 | PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER - This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon. | 03-26-2015 |
Alan Sutton, Wiltshire GB
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20130059018 | PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER - This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon. | 03-07-2013 |
Andrew Sutton, Thornborough GB
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20130166362 | System And Method For Promotional Discounted Aggregated Purchasing - A system, method, and computer program product provides discounted aggregated purchasing. A method for promotional discounted aggregated purchasing may include determining a volume discount matrix for a product to be available during a promotional period, accepting bids from a plurality of consumers indicating a price each consumer is willing to pay for the product, placing a hold on payment cards of the consumers who have entered bids, each hold being for the amount of each bid, at a conclusion of the promotional period, determining a price for the product based on a final discount level that is determined based on the received bids and on the determined volume discount matrix, and performing transactions for the product for all consumers who bid an amount greater than or equal to the determined price. | 06-27-2013 |
Andrew Derek Sutton, London GB
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20120164099 | USE OF HUMAN PROSTATE CELL LINES IN CANCER TREATMENT - This invention is concerned with agents for the treatment of primary, metastatic and residual cancer in mammals (including humans) by inducing the immune system of the mammal or human afflicted with cancer to mount an attack against the tumour lesion. In particular, the invention pertains to the use of whole-cells, derivatives and portions thereof with or without vaccine adjuvants and/or other accessory factors. More particularly, this disclosure describes the use of particular combinations of whole-cells and derivatives and portions thereof that form the basis of treatment strategy. | 06-28-2012 |
Charles William Sutton, North Lincolnshire GB
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20100101893 | Grease Distribution Bar - The invention provides an improved device for the lubrication of railway tracks in the form of grease distribution bar ( | 04-29-2010 |
Christopher Sutton, London GB
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20120089911 | Bookmarking System - A bookmarking system is described for allowing users to bookmark audio and video content for sharing with other users. The system allows the bookmark to be generated with minimal user involvement, making the process as easy to use as the bookmarking of websites on a computer device. A disambiguation server is provided to disambiguate the content to be book-marked. The disambiguation server uses information from various sources to provide a number of candidates for selection by the user. Historical data and the bookmarks of other users can also be used to aid the disambiguation process. | 04-12-2012 |
Christopher John Joseph Sutton, Cambridge GB
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20110125508 | DATA EMBEDDING SYSTEM - A data hiding system is described for hiding data within an audio signal. The system can be used for watermarking, data communications, audience surveying etc. The system hides data in an audio signal by adding artificial echoes whose polarity varies with the data to be hidden. In one embodiment, each data value is represented by a positive and a negative echo having different delays. A receiver can then remove the effects of natural echoes and/or periodicities in the audio signal by differencing measurements obtained at the different delays. | 05-26-2011 |
20120004920 | DATA EMBEDDING SYSTEM - A data hiding system is described for hiding data within an audio signal. The system can be used for watermarking, data communications, audience surveying etc. The system hides data in an audio signal by adding artificial echoes whose polarity varies with the data to be hidden. In one embodiment, each data value is represented by a positive and a negative echo having different delays. A receiver can then remove the effects of natural echoes and/or periodicities in the audio signal by differencing measurements obtained at the different delays. | 01-05-2012 |
Daniel J. Sutton, Portsmouth GB
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20130191893 | System and Method for Ensuring Anonymity to Provide Self Help Guidance - User access to a help system is provided in an anonymous manner. A provider organization distributes unique pre-generated unique user access codes to potential users. The user access codes include a general information portion and a random portion. When accessing the system for the first time, the user enters their unique user access code, a username, and password. The system associates the username with the password and with the user access code. Subsequent, the user logs into the system using the username and password. Data may be compiled and stored in association with the user access code for later retrieval and analysis to calculate statistics for provider organizations. | 07-25-2013 |
David Mark Sutton, London GB
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20150152449 | Lactate Production Process - A process for producing alkyl R-lactate from an initial compound comprising substructure (I) is provided. The process involves producing an intermediate comprising R,R- and S,S-lactide from the initial compound, wherein the initial compound is subjected to stereoisomerisation conditions; and reacting at least a portion of the intermediate with an alkyl alcohol to produce a product comprising alkyl R-lactate, wherein alkyl R-lactate is produced in the presence of an enzyme. Also provided are processes for the production of R-lactic acid, oligomeric R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex lactic acid. | 06-04-2015 |
Diane Sutton, Winchester Hampshire GB
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20110244454 | FREEZE-DRIED COMPOSITIONS FOR BIOCHEMICAL REACTIONS - The use of raffinose as a glass-forming agent for freeze-dried compositions intended for use in conducting chemical or biochemical reactions such as the PCR. Thus, for instance, there is provided a composition for carrying out a chemical or biochemical reaction, said composition being in a freeze-dried form and comprising (i) a set of reagents comprising at least some of the chemical or biochemical reagents necessary for conducting said chemical or biochemical reaction, and (ii) raffinose. Kits comprising these compositions and methods of using them form a further aspect of the invention. | 10-06-2011 |
Diane Rachel Sutton, Wiltshire GB
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20090068672 | DETECTION SYSTEM - The use of a red nucleic acid stain, in particular red fluorescent SYTO® dye in various methods used for the detection or characterisation of nucleic acids is described. In particular, the red nucleic acid stains have been found to be particularly compatible with the polymerase chain reaction (PCR), and therefore form the basis of enhanced detection methods. | 03-12-2009 |
J. Mark Sutton, Salisbury GB
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20090186368 | Assay with reduced background - In an assay, an analyte in a sample is contacted with a thermostable reporter adenylate kinase coupled to a binding agent specific for the analyte, wherein a complex is formed. ADP is added, and then formation of ATP is monitored. Prior to the addition of ADP, endogenous kinase and uncomplexed thermostable reporter adenylate kinase is substantially removed by washing and residual endogenous kinase is inactivated by heating. Prior to contacting the analyte with the thermostable reporter adenylate kinase, the sample has a background activity of at least 300,000 Relative Light Units per mg protein per ml sample when measured in the presence of luciferin/luciferase by a luminometer. | 07-23-2009 |
20090246827 | RECOMBINANT TOXIN FRAGMENTS - A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the polypeptide, or both. The polypeptide thus combines useful properties of a clostridial toxin, such as a botulinum or tetanus toxin, without the toxicity associated with the natural molecule. The polypeptide can also contain a third domain that targets it to a specific cell, rendering the polypeptide useful in inhibition of exocytosis in target cells. Fusion proteins comprising the polypeptide, nucleic acids encoding the polypeptide and methods of making the polypeptide are also provided. Controlled activation of the polypeptide is possible and the polypeptide can be incorporated into vaccines and toxin assays. | 10-01-2009 |
20090274708 | Recombinant Toxin Fragments - Antigenic compositions are provided comprising a single chain polypeptide comprising first and second domains, wherein said first domain is a clostridial neurotoxin light chain or a fragment or a variant thereof and is capable of cleaving one or more vesicle or plasma membrane associated proteins essential to exocytosis; and said second domain is a clostridial neurotoxin heavy chain H | 11-05-2009 |
20100022751 | RECOMBINANT TOXIN FRAGMENTS - A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the polypeptide, or both. The polypeptide thus combines useful properties of a clostridial toxin, such as a botulinum or tetanus toxin, without the toxicity associated with the natural molecule. The polypeptide can also contain a third domain that targets it to a specific cell, rendering the polypeptide useful in inhibition of exocytosis in target cells. Fusion proteins comprising the polypeptide, nucleic acids encoding the polypeptide and methods of making the polypeptide are also provided. Controlled activation of the polypeptide is possible and the polypeptide can be incorporated into vaccines and toxin assays. | 01-28-2010 |
20110028691 | RECOMBINANT TOXIN FRAGMENTS - A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the polypeptide, or both. The polypeptide thus combines useful properties of a clostridial toxin, such as a botulinum or tetanus toxin, without the toxicity associated with the natural molecule. The polypeptide can also contain a third domain that targets it to a specific cell, rendering the polypeptide useful in inhibition of exocytosis in target cells. Fusion proteins comprising the polypeptide, nucleic acids encoding the polypeptide and methods of making the polypeptide are also provided. Controlled activation of the polypeptide, is possible and the polypeptide can be incorporated into vaccines and toxin assays. | 02-03-2011 |
20130288353 | BIOLOGICAL INDICATOR - A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for validation of sterilisation treatment. The formation of ATP from a substrate comprising ADP is measured via the liciferin/luciferate system in a luminameter. Thermostable adenylate kinase from sulfolobus acidocaldarius is especially suitable for the validation of procedures to inactivate transmissable spongiform encephalopathy agents. | 10-31-2013 |
J. Mark Sutton, Salisbury, Wiltshire GB
Patent application number | Description | Published |
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20090148888 | RECOMBINANT TOXIN FRAGMENTS - A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the polypeptide, or both. The polypeptide thus combines useful properties of a clostridial toxin, such as a botulinum or tetanus toxin, without the toxicity associated with the natural molecule. The polypeptide can also contain a third domain that targets it to a specific cell, rendering the polypeptide useful in inhibition of exocytosis in target cells. Fusion proteins comprising the polypeptide, nucleic acids encoding the polypeptide and methods of making the polypeptide are also provided. Controlled activation of the polypeptide is possible and the polypeptide can be incorporated into vaccines and toxin assays. | 06-11-2009 |
20110177539 | COVALENTLY LINKED THERMOSTABLE KINASE FOR DECONTAMINATION PROCESS VALIDATION - A biological process indicator is provided for validating a treatment process in which the amount or activity of a contaminant in a sample is reduced. The indicator comprises a thermostable kinase covalently linked to a biological component, with the proviso that the biological component is not an antibody. Methods of preparing the indicator, and methods of using the indicator, are also provided. | 07-21-2011 |
J. Mark Sutton, Wiltshire GB
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20090087877 | INFECTIVITY ASSAY - There is provided a method for infecting a target cell with a TSE agent, comprising: i) contacting said target cell with a membrane preparation, wherein the membrane preparation comprises the TSE agent and a donor membrane; and ii) infecting said target cell with the TSE agent. There is also provided a contiguous membrane, comprising a donor membrane and a membrane containing a TSE agent, wherein the TSE agent is selected from the group consisting of CJD, vCJD, familial CJD (e.g. FFI or CSS), iatrogenic CJD, BSE, ovine BSE, and CWD. | 04-02-2009 |
20090317794 | BIOLOGICAL INDICATOR - A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for validation of sterilisation treatment. The formation of ATP from a substrate comprising ADP is measured via the liciferin/luciferate system in a luminameter. Thermostable adenylate kinase from | 12-24-2009 |
John Mark Sutton, Salisbury GB
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20090269361 | Constructs for delivery of therapeutic agents to neuronal cells - A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a H | 10-29-2009 |
John Mark Sutton, Salisbury Wiltshire GB
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20140315215 | THERMOSTABLE ASSAY REAGENTS - There is provided a single-chain fusion protein comprising: (i) a thermostable kinase and (ii) a single-domain antibody or single-domain antibody fragment. There is also provided a method of preparing a single-domain antibody or single-domain antibody fragment, the method comprising: (i) expressing the single-domain antibody or antibody fragment as a single-chain fusion protein with a thermostable kinase, in a host cell such as | 10-23-2014 |
John Mark Sutton, Abingdon GB
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20120128700 | CONSTRUCTS FOR DELIVERY OF THERAPEUTIC AGENTS TO NEURONAL CELLS - A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a H | 05-24-2012 |
John Scott Sutton, Bristol GB
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20140205470 | FAN ASSEMBLY - A bladeless fan assembly for creating an air current includes a nozzle mounted on a base housing a device for creating an air flow. The nozzle includes an interior passage for receiving the air flow and a mouth for emitting the air flow. The nozzle defines, and extends about, an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth. The nozzle also includes a heater for heating the air flow upstream of the mouth. | 07-24-2014 |
20150093098 | FAN ASSEMBLY - A bladeless fan assembly for creating an air current includes a nozzle mounted on a base housing a device for creating an air flow. The nozzle includes an interior passage for receiving the air flow and a mouth for emitting the air flow. The nozzle defines, and extends about, an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth. The nozzle also includes a heater for heating the air flow upstream of the mouth. | 04-02-2015 |
John Scott Sutton, Malmesbury GB
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20100132154 | SURFACE TREATING APPLIANCE - A surface-treating appliance, such as a vacuum cleaner, includes a main body housing a component such as a post-motor filter. A door provides access to the filter. The door is connected to the main body by a hinge arranged to allow the door to pivot about the hinge's rotational axis and to move axially as the door is moved between closed and open positions. The provision of a hinge that can move along its rotational axis permits the door to move laterally as it opens, thereby clearing adjacent parts of the appliance, such as the spine. This allows an appliance to be manufactured that permits the user to access components housed inside of it, but is compact. Preferably, the hinge includes a cam arrangement, so that the door automatically moves away from adjacent parts of the appliance as it moves from the closed position to an open position. | 06-03-2010 |
20100225012 | HUMIDIFYING APPARATUS - Humidifying apparatus includes a humidifier for emitting moist air into an external environment, and a fan assembly for generating an air current within the external environment for conveying the emitted moist air away from the humidifier. The fan assembly includes a device for creating an air flow and a nozzle comprising an interior passage for receiving the air flow and a mouth for emitting the air flow. The humidifier is located behind nozzle, the nozzle extending about and defining an opening through which both air from outside the nozzle and the moist air emitted from the humidifier are drawn by the air flow emitted from the mouth. | 09-09-2010 |
20100226797 | FAN ASSEMBLY - A bladeless fan assembly for creating an air current includes a nozzle mounted on a base housing a device for creating an air flow. The nozzle includes an interior passage for receiving the air flow and a mouth for emitting the air flow. The nozzle defines, and extends about, an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth. The nozzle also includes a heater for heating the air flow upstream of the mouth. | 09-09-2010 |
20120230658 | FAN ASSEMBLY - A bladeless fan assembly for creating an air current includes a nozzle mounted on a base housing a device for creating an air flow. The nozzle includes an interior passage for receiving the air flow and a mouth for emitting the air flow. The nozzle defines, and extends about, an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth. The nozzle also includes a heater for heating the air flow upstream of the mouth. | 09-13-2012 |
20120284960 | SURFACE TREATING APPLIANCE - A surface treating appliance includes a first cyclonic separating unit including at least one first cyclone, a second cyclonic separating unit including a plurality of second cyclones arranged in parallel about an axis, and a third cyclonic separating unit including a plurality of third cyclones arranged in parallel about the axis. Each of the second cyclones and the third cyclones has a tapering body with an outside wall. The plurality of third cyclones is divided into at least a first set of third cyclones and a second set of third cyclones, each of the plurality of second cyclones and the first set of third cyclones being arranged about the second set of third cyclones. At least a part of the outside wall of each of the plurality of second cyclones and each of the first set of third cyclones forms part of the external surface of the surface treating appliance. | 11-15-2012 |
20130161842 | HUMIDIFYING APPARATUS - Humidifying apparatus includes a humidifier for emitting moist air into an external environment, and a fan assembly for generating an air current within the external environment for conveying the emitted moist air away from the humidifier. The fan assembly includes a device for creating an air flow and a nozzle comprising an interior passage for receiving the air flow and a mouth for emitting the air flow. The humidifier is located behind nozzle, the nozzle extending about and defining an opening through which both air from outside the nozzle and the moist air emitted from the humidifier are drawn by the air flow emitted from the mouth. | 06-27-2013 |
John Scott Sutton, Gloucester GB
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20160100730 | VACUUM CLEANER - A vacuum cleaner comprising a dirty air intake and a cyclonic separating apparatus connected in series. The cyclonic separating apparatus comprises a plurality of cyclonic separators connected in parallel. The vacuum cleaner further comprises a bleed valve provided upstream of the plurality of cyclonic separators. The bleed valve opens to admit bled air into the plurality of cyclonic separators in response to a drop in pressure in the vacuum cleaner. The bleed valve is also connected to the inlets of the plurality of cyclonic separators via a common plenum. | 04-14-2016 |
Jonathan Sutton, York GB
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20120160160 | APPARATUS FOR DEPOSITING - An apparatus for depositing a liquid, semi-liquid or semi-solid food product. The apparatus comprises a fixed volume chamber for receiving the food product under a positive pressure, the chamber being defined by chamber walls, one of the chamber walls being provided with an outlet orifice for depositing the food product, the outlet orifice being provided with a first sealing surface. The apparatus also comprises a valve spindle arranged for reciprocating movement within the chamber, the length direction of the valve spindle extending substantially perpendicular to the chamber wall in which the outlet orifice is provided, a first end of the valve spindle being provided with a second sealing surface. The second sealing surface of the valve spindle is arranged for abutting the first sealing surface of the outlet orifice to thereby close the outlet orifice. | 06-28-2012 |
Jonathan M. Sutton, Harlow GB
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20090143437 | EP4 RECEPTOR ANTAGONISTS - Compounds of formula (X): | 06-04-2009 |
Jonathan Mark Sutton, Essex GB
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20080306117 | EP4 RECEPTOR ANTAGONISTS - A compound of formula (I): | 12-11-2008 |
20090192138 | COMPOUNDS - The invention provides novel deazaxanthine and deazahypoxanthine compounds. The compounds may be useful in the therapy of diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated. | 07-30-2009 |
20100130556 | EP2 RECEPTOR AGONISTS - A compound of formula (III): or a salt, solvate and chemically protected form thereof, wherein: R | 05-27-2010 |
Jonathan Mark Sutton, Harlow GB
Patent application number | Description | Published |
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20090298899 | EP2 RECEPTOR AGONISTS - The disclosure provides EP | 12-03-2009 |
20100261760 | EP2 Receptor Agonists - The disclosure provides EP2 receptor agonist compounds and methods for using the compounds for treating conditions which can be alleviated by agonism of an EP2 receptor. | 10-14-2010 |
20130065913 | NOVEL COMPOUNDS - Compounds of formula (I): | 03-14-2013 |
20140018345 | INHIBITION OF ENZYMES - Compounds of formula (I): | 01-16-2014 |
20140171414 | NOVEL COMPOUNDS - Compounds of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and conditions in which HNE is implicated. | 06-19-2014 |
20140179714 | NOVEL COMPOUNDS - Compounds of formula (I): | 06-26-2014 |
20150353561 | NOVEL COMPOUNDS - Compounds of formula (I), described herein, exhibit human neutrophil elastase inhibitory properties, and are useful for the treatment of diseases and conditions in which HNE is implicated. | 12-10-2015 |
Joseph Peter Sutton, Southampton GB
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20110088708 | SMOKING ARTICLES AND SMOKABLE FILLER MATERIAL THEREFOR - The invention relates to smokable filler materials and a process for making same, the smokable filler material comprising a foaming agent, an agent capable of forming chemical cross-linkages, and a cross-linking agent. A combination of the foaming agent in the foamed state thereof, the agent capable of forming chemical crosslinkages and the cross-linking agent provides a stabilised, foamed material. The invention also provides a smoking article incorporating the smokable filler material of the invention. | 04-21-2011 |
Joseph Peter Sutton, London GB
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20120085359 | Smoking Article - A smoking article ( | 04-12-2012 |
20120305014 | Filter for a Smoking Article | 12-06-2012 |
20150296868 | SMOKELESS ORAL TOBACCO PRODUCT AND PREPARATION THEREOF - A smokeless oral tobacco product is provided comprising an insoluble foamed material. The insoluble foamed material is formed by combining a foaming agent, an agent capable of forming chemical cross-linkages and a cross-linking agent. A method of producing a smokeless oral tobacco product comprising an insoluble foamed material is also provided. | 10-22-2015 |
Karen Lorraine Sutton, Camberley GB
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20090016980 | Method of Pre-Treating Hair Prior to Coloring - The present invention relates to the field of hair coloring. More specifically, the present invention relates to a method of pre-treating hair prior to the application of a hair colorant. The method comprises the steps of applying a pre-treatment composition, comprising a monoalkyl quat, a cellulose thickener, and a quaternary silicone, on all the hair and leaving the pre-treatment composition on the hair, without rinsing it off prior to the application of the colorant. | 01-15-2009 |
Kathy Sutton, Herts GB
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20140066426 | FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES - The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. | 03-06-2014 |
Kathy Sutton, Hertfordshire GB
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20150291572 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES - The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. | 10-15-2015 |
20150291573 | ARYL SUBSTITUTED HETEROCYCLYL SULFONES - The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. | 10-15-2015 |
Mark J. Sutton, Salisbury Wiltshire GB
Patent application number | Description | Published |
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20110318729 | Rapid Bioluminescence Detection Assay - An assay is provided for detecting the activity of a reporter kinase comprising (i) adding said reporter kinase to an assay mixture wherein said reporter kinase is contacted with bioluminescent reagent no more than minutes after being contacted with ADP, and wherein, prior to contacting the reporter kinase with ADP, the assay mixture is substantially free from kinase other than reporter kinase; and (ii) detecting light output from the assay mixture. Methods for detecting the presence of an analyte in a sample and methods for validating a treatment process using the above assay are also provided. Further provided are devices for conducting these assays and methods. | 12-29-2011 |
Mark J. Sutton, Salisbury GB
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20140030740 | Rapid Bioluminescence Detection System - An assay is provided for detecting the activity of a reporter kinase comprising (i) adding said reporter kinase to an assay mixture wherein said reporter kinase is contacted with bioluminescent reagent no more than 5 minutes after being contacted with ADP, and wherein, prior to contacting the reporter kinase with ADP, the assay mixture is substantially free from kinase other than reporter kinase; and (ii) detecting light output from the assay mixture. Methods for detecting the presence of an analyte in a sample and methods for validating a treatment process using the above assay are also provided. Further provided are devices for conducting these assays and methods. | 01-30-2014 |
Michael Sutton, Matlock GB
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20100152082 | Polymer and Lubricating Compositions Thereof - The invention provides a lubricating composition containing an oil of lubricating viscosity and a hydrogenated copolymer of an olefin block and vinyl aromatic block, wherein the copolymer is optionally functionalised. The invention further provides a method for preparing a hydrogenated copolymer; and the use of the lubricating composition. | 06-17-2010 |
Michael R. Sutton, Matlock GB
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20110015105 | Lubricating Composition Containing Overbased Detergent - The invention provides a lubricating composition containing an oil of lubricating viscosity and a calcium-containing detergent with a soap content of 0.06 wt % to 1.6 wt % of the lubricating composition. The lubricating composition is suitable for lubricating an internal combustion engine. | 01-20-2011 |
20110059881 | Sulphur Free Composition And Lubricant Composition And Methods Thereof - A composition comprises a sulphur free reaction product of: (a)(i) a hydrocarbyl substituted aromatic compound containing an acidic group selected from the group consisting of a carboxylic group, a hydroxyl group and mixtures thereof; and (a)(ii) an organic nitrogen-containing base reacted with the acidic group. The composition is obtained by a preparatory process and is useful in a method for lubricating an internal combustion engine to include where the lubricant has reduced levels of sulphur, phosphorus and sulphated ash. | 03-10-2011 |
20110218129 | Delivery of Substantially Insoluble Additives to Functional Fluids - In accordance with the present invention, it has been discovered that an additive which is substantially insoluble in, has low solubility in and/or is otherwise incompatible with a functional fluid, may be supplied to the functional fluid by use of a gel composition and/or a solid additive composition containing the additive, such that the functional fluid can receive the benefit of the supplied additive and/or contain levels of the additive not otherwise achievable by conventional delivery method due to the incompatibility of the additive with the functional fluid. | 09-08-2011 |
20120178656 | Dispersant Viscosity Modifiers - The disclosed invention relates to a composition comprising a grafted polymer. The polymer backbone comprises an olefin block and a vinyl aromatic block. The polymer backbone is grafted with a pendant carbonyl containing group, the grafting being conducted in oil in the presence of an initiator. The carbonyl containing-group is optionally substituted to provide ester, imide and/or amide functionality. The grafted polymer is useful as a dispersant viscosity modifier in lubricating compositions such as engine oils. | 07-12-2012 |
20120178659 | Dispersant Viscosity Modifiers - The disclosed invention relates to a composition comprising a grafted polymer. The polymer comprises a backbone with at least one olefin block and at least one vinyl aromatic block. The polymer is grafted with a pendant carbonyl containing group, the grafting being conducted by halogenating the vinyl aromatic carbon of the vinyl aromatic block and then grafting a carboxylic acid or derivative thereof on the halogenated vinyl aromatic carbon in the presence of an activating agent. The carbonyl containing-group is optionally substituted to provide ester, imide and/or amide functionality. The grafted polymer is useful as a dispersant viscosity modifier in lubricating compositions such as engine oils. | 07-12-2012 |
20120196778 | Lubricating Composition Containing an Antiwear Agent - The invention provides a lubricating composition containing (a) an oil of lubricating viscosity, (b) a phosphite having at least one hydrocarbyl group that has 4 or more carbon atoms, and (c) a compound derived from a hydroxy-carboxylic acid. The invention further relates to the use of the lubricating composition in an internal combustion engine. | 08-02-2012 |
20120289444 | Star Polymer Lubricating Composition - The invention provides a lubricating composition containing (a) 0.001 wt % to 15 wt % of a polymer with radial or star architecture; (b) an overbased detergent; (c) a dispersant; and (d) an oil of lubricating viscosity. The invention further provides a method for lubricating a mechanical device with the lubricating composition. | 11-15-2012 |
20140020468 | Ultrasonic Measurement - Methods and apparatus relate to ultrasound measurement of a dimension such as the thickness ( | 01-23-2014 |
20140057818 | Lubricating Composition Containing an Antiwear Agent - The invention provides a lubricating composition containing an antiwear agent and an oil of lubricating viscosity. The invention further relates to the use of the lubricating composition in an internal combustion engine, or a driveline device. | 02-27-2014 |
20140274850 | Lubricating Composition Comprising Poly (Isobutylene) /Poly (Vinyl Aromatic) Block Copolymer - The invention provides a lubricating composition containing an oil of lubricating viscosity and a block copolymer of a poly(olefin) block, such as poly(isobutylene) (PIB) and a polyvinyl aromatic) block, such as poly(styrene), wherein the copolymer is optionally functionalized or grafted. The invention further provides a method of using the block copolymer to control deposits in a lubricating oil composition. | 09-18-2014 |
20150053005 | Ultrasonic Measurement - Ultrasonic measurement apparatus | 02-26-2015 |
Michael R. Sutton, Derbyshire GB
Patent application number | Description | Published |
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20090298729 | Star Polymer Lubricating Composition - The invention provides a lubricating composition containing (a) 0.001 wt % to 15 wt % of a polymer with radial or star architecture; (b) an overbased detergent; (c) a dispersant; and (d) an oil of lubricating viscosity. The invention further provides a method for lubricating a mechanical device with the lubricating composition. | 12-03-2009 |
Michael R. Sutton, Belper GB
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20150203784 | Lubricating Composition Including Esterified Copolymer And Diene Rubber Polymer - A lubricating composition includes (A) an esterified copolymer comprising units (A1) derived from a vinyl monomer and units (A2) derived from a carboxylic acid monomer, the vinyl monomer comprising a vinyl aliphatic monomer, the carboxylic acid monomer comprising an ethylenically unsaturated carboxylic acid or derivative thereof, esterified with a primary alcohol; and (B) a diene rubber copolymer comprising at least a first block (B1) derived from a conjugated diene monomer and at least a second block (B2) derived from a vinyl aromatic monomer. A ratio of the diene rubber copolymer to the esterified copolymer in the lubricating composition (B:A) is from 0.01 to 0.9, by weight. | 07-23-2015 |
Nathan D. Sutton, Banbury GB
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20110276358 | Allocation of work items via queries of organizational structure and dynamic work item allocation - Disclosed are systems and methods for identifying one or more individuals in an organizational model to work on a particular work item where the method includes receiving a query having one or more attributes where the one or more attributes indicate the criteria for one or more individuals to work on a particular work item. The systems and methods further include searching an organizational model for the one or more individuals associated with the attributes defined in the query, and identifying the one or more individuals associated with the attributes defined in the query. The systems and methods also include allocating or offering the particular work item to the one or more of the individuals associated with the one or more attributes defined in the query. | 11-10-2011 |
Neal Sutton, Baldock GB
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20130243659 | DIESEL PARTICULATE FILTER - A method of making a filter for filtering particulate matter from exhaust gas emitted from a lean-burn internal combustion engine, which filter comprising a porous substrate having inlet surfaces and outlet surfaces, wherein the inlet surfaces are separated from the outlet surfaces by a porous structure containing pores of a first mean pore size, wherein the inlet surfaces comprise a bridge network comprising interconnected particles of refractory material over the pores of the porous structure, which method comprising the step of contacting inlet surfaces of the filter substrate with an aerosol comprising refractory material in dry powder form. The invention also relates to a filter obtainable by such method. | 09-19-2013 |
Philip Sutton, Birmingham GB
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20090208286 | Synthetic Kerbs and Method of Installation - A plastics or rubber kerbstone ( | 08-20-2009 |
Richard Sutton, Gloucestershire GB
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20160089083 | Posture Monitor - A posture monitoring device | 03-31-2016 |
Robert Sutton, Merseyside GB
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20150053206 | Half Facepiece - A half facepiece respirator has a shaped support piece supporting and fixing the position of a particle or paper filter insert or outsert with either the support piece or the particle filter incorporating a face sealing component. Placed within the shaped support piece, a grille may be placed in the lower section of the shaped support piece. Additionally the half facepiece includes a head harness having a release mechanism. | 02-26-2015 |
Robert C. Sutton, Merseyside GB
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20150090751 | CARRYING PLATE FOR BREATHING APPARATUS - A mounting assembly for a self-contained breathing apparatus (SCBA) includes a back plate defining a plurality of apertures therein that are arranged in two columns extending down opposing side edges of the back plate. The apertures are sized and spaced to receive mounting straps that are configured to interface with webbing straps of a carrying jacket to fasten the back plate to the jacket. The mounting assembly also includes a tank securing strap with a quick release mechanism that is fastened to the back plate. The tank securing strap is configured to engage a supply tank to releasably fasten the tank to the back plate. The mounting assembly further includes a valve retaining mount disposed on the plate. The valve retaining mount is configured to releasably secure an air supply valve to the back plate for engagement with the supply tank. | 04-02-2015 |
Robert Charles Sutton, Southport GB
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20150314146 | RESPIRATORS - A respirator comprising an outer mask in which is defined a main volume and an oronasal mask located within the outer mask and defining a secondary volume. Air for breathing enters the mask via a one-way valve and filter. Exhaled air exits the mask via an exhale conduit fitted with an exhale valve. A conduit is provided for the passage of air from the outer mask to the oronasal mask. The conduit is fitted with a one-way valve and a filter. The filter is such as to filter either particular or vapor challenges, or a mixture of these, as required. | 11-05-2015 |
Robert Charles Sutton, Merseyside GB
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20150047642 | Half Facepiece - A semi-disposable face mask has a shaped molded base composed of silicone and/or TPE and molded forming a face seal, a filter media and a support structure that houses the shaped molded base and filter media in fluid communication allowing airflow from an environment through the filter media to the face seal. | 02-19-2015 |
Sean Sutton, Bridgwater GB
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20150121195 | CONTENT DISPLAY - The present invention relates to a system | 04-30-2015 |
Simon Sutton, Coventry GB
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20140297139 | IMPROVEMENTS IN VEHICLE TRANSMISSIONS HAVING A PARK FUNCTION - In response to driver selection of PARK, a vehicle transmission is commanded to momentarily select and hold NEUTRAL before PARK, whilst a vehicle wheel brake is applied. Such an arrangement avoids trapping torque in the driveline, and thus can obviate pawl ‘thump’ when PARK is next disengaged. | 10-02-2014 |
Simon Sutton, Warwickshire GB
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20140330493 | METHOD AND APPARATUS FOR CONTROLLING THE ENGAGEMENT OF AN INPUT GEAR WITH AN OUTPUT GEAR - The present invention relates to a method of engaging an input gear with an output gear in a drivetrain ( | 11-06-2014 |
Simon Sutton, Egham GB
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20130175068 | Recyclable Thermoplastic Insulation with Improved Breakdown Strength - The disclosure provides a process for producing a material with improved break-down strength. The process includes heating a polymeric composition composed of a low density polyethylene (LDPE) and a minority amount of a high density polyethylene (HDPE). The polymeric composition is heated to at least the melting temperature of the HDPE. The process includes control-cooling the heated polymeric composition at a cooling rate from 0.1° C./min to 20° C./min, and forming a polymeric composition. The control-cooled polymeric composition has a unique morphology which improves breakdown strength. Also provided is a coated conductor with an insulating layer composed of the polymeric composition with the unique morphology. The insulating layer exhibits improved breakdown strength. | 07-11-2013 |
Simon J Sutton, Egham GB
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20150087787 | POLYPROPYLENE BLENDS AND PROCESSES FOR PRODUCING POLYMERIC COMPOSITIONS - Polymer blends of polypropylene homopolymer and propylene-α-olefin interpolymer. Processes for producing polymeric compositions comprising control-cooling heated blends of polypropylene and propylene-α-olefin interpolymer. Such polymeric compositions can be employed in forming coated wires and cables. | 03-26-2015 |
Stephen Sutton, Dorset GB
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20080232422 | Laser Radiation Source - A transmitter unit is described for an open path gas detector. The unit comprises: an enclosure having a window; and a coherent radiation transmitter, e.g. a tuneable laser diode transmitter, located within the enclosure and configured to direct a beam of radiation through the window. The window is slanted with respect to the axis of the beam emitted by the transmitter such that no radiation from the transmitter that is directly incident on the window is reflected by the window directly onto the transmitter. Thereby interference fringes within the emitted radiation are reduced. Alternatively, the window may be replaced by a lens followed by an aperture such that the beam emitted by the transmitter is focused onto the aperture, thereby forming a beam of radiation passing out of the enclosure. | 09-25-2008 |
Stephen George Sutton, Hertfordshire GB
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20090114257 | Handle and a Walking Aid Incorporating the Same - A walking aid comprises a leg with a handle located part way up the leg; the leg having a region below the handle which in use may engage the ground as a user leans onto the walking aid; and a region above said handle for supporting the arm of the user, the walking aid having the handle is an inclined elongate handle located between the leg's upper and lower regions the leg's handle, upper and lower regions have a common supporting bar; an arm being located across and beneath the handle between said upper and lower regions; and the arm formed of two parts which are clamped together to be secured onto the leg at the handle region; and/or the upper region is bowed; and/or said region for supporting the arm incorporates a cuff with a lateral opening and means allowing the cuff to be selectively attached to the leg with the opening in a first radial direction for use with the right arm and with the opening in a second radial direction for use with the left arm; and/or said walking aid incorporates a region above said handle for supporting the arm of the user which has a brace spaced from said handle sufficiently to be located over the lower forearm region above the wrist; and/or in addition to the inherent shock absorption of the handle, a damping compound is provided and located at least in part within the handle to cushion the pressure exerted by a user's hand on the handle; and/or a shock absorber is provided in close proximity to said handle as an integral part of the walking aid. | 05-07-2009 |
Stephen N. Sutton, Dorset GB
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20090231588 | OPTICAL GAS DETECTION - The present invention provides a transmitter unit for an open path gas detector for detecting a target gas and comprises: a radiation transmitter, e.g. a tuneable laser diode, capable of emitting radiation at a wavelength absorbed by the target gas, and a radiation deflector, having a deflecting part and a non-deflecting part, e.g. a mirror having a non-reflective part. The deflecting part and the non-deflecting part are located in the path of the radiation emitted by the transmitter and the non-deflecting part does not deflect the said radiation emitted by the transmitter or does so to a different extent than the deflecting part. In this way, the beam has a core in shadow that can be used to align the beam with a receiver unit. The radiation deflector is preferably a mirror having a reflective surface for reflecting radiation emitted by the transmitter and a non-reflective part that does not reflect the said radiation emitted by the transmitter or does so to a lesser extent that the reflecting surface. The non-reflective part is preferably transparent so that it allows radiation to pass through it, which can be used to measure the wavelength of the transmitter and, if necessary correct it. | 09-17-2009 |
Tony Sutton, Harmston GB
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20100033432 | Trackball - A pointing device such as a scrolling device or trackball, including a ball formed at least partially from an electrically conductive material, and a PCB including a capacitive proximity sensor, wherein movement data representative of ball movement is communicated by a controller to an interface such as a monitor screen, and wherein an electrical switch is actuable in response to the proximity of the sensed object to the ball, such that when a user is not in contact with or in close proximity to the ball, movement data will not be communicated by the controller to the interface. | 02-11-2010 |