Patent application number | Description | Published |
20100095513 | APPARATUSES FOR CRIMPING AND LOADING OF INTRALUMINAL MEDICAL DEVICES - Crimping apparatuses for reducing the diameter of an intraluminal medical device from a first diameter to a second diameter prior to loading the medical device into a catheter delivery system and loading apparatuses for introducing the medical device into a catheter delivery system, the devices constructed and arranged for matingly engaging one another, combinations thereof, and methods of using the devices. | 04-22-2010 |
20100274342 | STENT CRIMPING MECHANISMS - A system for reducing the diameter of a stent comprises a stent contracting assembly. The assembly comprises a plurality of blades, which define a diameter reduction chamber. The chamber has an open diameter configuration and a closed diameter configuration. The plurality of blades comprises active blades and floating blades, wherein each active blade is engaged to an actuation mechanism. The actuation mechanism is constructed and arranged to move each active blade from the open diameter configuration to the closed diameter configuration. Each floating blade is moved from the open diameter configuration to the closed diameter configuration only as a result of the movement of the active blades. | 10-28-2010 |
20110162432 | APPARATUSES FOR CRIMPING AND LOADING OF INTRALUMINAL MEDICAL DEVICES - Crimping apparatuses for reducing the diameter of an intraluminal medical device from a first diameter to a second diameter prior to loading the medical device into a catheter delivery system and loading apparatuses for introducing the medical device into a catheter delivery system, the devices constructed and arranged for matingly engaging one another, combinations thereof, and methods of using the devices. | 07-07-2011 |
Patent application number | Description | Published |
20090292347 | SYSTEMS AND METHODS FOR HEATING AND COOLING DURING STENT CRIMPING - Methods of heating and cooling during a crimping process are disclosed. One method includes providing a cooling source to cool the stent and/or drug eluting coating of the stent while crimping the stent onto the balloon, and providing a heating source to heat the balloon while crimping the stent onto the balloon. Another method includes introducing a cooling fluid through a passage in one or more of the plurality of crimping elements of the crimping apparatus to cool the crimping elements while crimping the stent onto the balloon, and introducing a heating fluid through the elongate shaft of the balloon catheter to heat the balloon while crimping the stent onto the balloon. | 11-26-2009 |
20140187986 | PRESSURE-SENSING GUIDEWIRE AND SHEATH - A pressure sensing device is provided that can monitor and measure pressure at two points in a vessel or artery without moving the outer sheath or catheter of the device. The outer sheath or catheter includes two spaced apart openings that may be positioned in a vessel or artery on opposing sides of an occlusion. The device also includes an inner elongated tube with at least one opening. The inner elongated tube is slidable with respect to the outer sheath or catheter thereby permitting the opening of the elongated tube to be moved into selective registration with one of the openings of the outer sheath. A pressure measurement may be taken through one of the openings in the outer sheath by aligning the opening of the elongated tube with said opening and, then, a second pressure reading may be taken by sliding the elongated tube within the outer sheath so that the opening of the elongated tube is in registry with the other opening of the tubular sheath. As a result, pressure measurements at two points in a vessel or artery may be taken without moving the outer sheath or catheter. | 07-03-2014 |
20150359445 | PRESSURE-SENSING GUIDEWIRE AND SHEATH - A pressure sensing device is provided that can monitor and measure pressure at two points in a vessel or artery without moving the outer sheath or catheter of the device. The outer sheath or catheter includes two spaced apart openings that may be positioned in a vessel or artery on opposing sides of an occlusion. The device also includes an inner elongated tube with at least one opening. The inner elongated tube is slidable with respect to the outer sheath or catheter thereby permitting the opening of the elongated tube to be moved into selective registration with one of the openings of the outer sheath. A pressure measurement may be taken through one of the openings in the outer sheath by aligning the opening of the elongated tube with said opening and, then, a second pressure reading may be taken by sliding the elongated tube within the outer sheath so that the opening of the elongated tube is in registry with the other opening of the tubular sheath. As a result, pressure measurements at two points in a vessel or artery may be taken without moving the outer sheath or catheter. | 12-17-2015 |
20160038719 | REFORMABLE GUIDEWIRE TIP - Devices and methods for providing an elastically deforming guidewire tip, capable of withstanding the extreme forces of high-speed rotational atherectomy, in particular orbital motion induced by an eccentric abrasive head, are disclosed. In certain embodiments, the reformable tip comprises an inner nitinol support coil, wherein the reformable tip may be attached to a larger proximal core for improved kink resistance and support for delivering adjunctive devices. In other embodiments, an inner nitinol support coil may be wrapped with a braided coil and/or a polymer sleeve. The resulting tip is more flexible with reduced risk of perforation than known guidewire tips. | 02-11-2016 |
Patent application number | Description | Published |
20100235933 | Kaspp (lrrk2) gene, its production and use for the detection and treatment of neurodegenerative disorders - The present invention refers to a newly discovered gene named KASPP for Kinase Associated with Parkinsonism with Pleiomorphic Pathology or alternatively named LRRK2 for Leucine-Rich Repeat Kinase 2, its production, biochemical characterization and use for the detection and treatment of neurodegenerative disorders, such as Parkinson disease (PD) including, without limitation, sporadic PD, Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and other synucleinopathies and/or tauopathy as well as several polymorphisms and mutations in the KASPP/LRRK2 gene segregated with PD. | 09-16-2010 |
20120035072 | KASPP (LRRK2) GENE, ITS PRODUCTION AND USE FOR THE DETECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention refers to a newly discovered gene named KASPP for Kinase Associated with Parkinsonism with Pleiomorphic Pathology or alternatively named LRRK2 for Leucine-Rich Repeat Kinase 2, its production, biochemical characterization and use for the detection and treatment of neurodegenerative disorders, such as Parkinson disease (PD) including, without limitation, sporadic PD, Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and other synucleinopathies and/or tauopathy as well as several polymorphisms and mutations in the KASPP/LRRK2 gene segregated with PD. | 02-09-2012 |