Patent application number | Description | Published |
20080214380 | Glass Substrate with Low Infrared Transmission for Display Screen - The invention relates to the field of display panels, especially field-emission display panels. | 09-04-2008 |
20100101275 | GLASS MAKING METHOD - The subject of the invention is a process for manufacturing red glass containing copper that comprises the steps consisting in:
| 04-29-2010 |
20120313134 | GLASS SUBSTRATE COATED WITH A HIGH-INDEX LAYER UNDER AN ELECTRODE COATING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SUCH A SUBSTRATE - A glass substrate including a first face and a second face opposing the first face, the substrate including, above the second face, an electrode layer which includes at least one electrically conducting layer, wherein the substrate includes, between the second face and the electrode layer, at least one layer of vitreous material having an index in the range from 1.7to 2.4and including from 40% to 60% by weight of bismuth oxide Bi | 12-13-2012 |
20130221336 | SUPPORT WITH A DIFFUSING LAYER FOR AN ORGANIC LIGHT-EMITTING DIODE DEVICE, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SUCH A SUPPORT - A support for an organic light-emitting diode device successively includes a transparent substrate, made of mineral glass, provided with first and second opposite main faces, the substrate being coated on its second face with a diffusing layer which includes a vitreous mineral binder and diffusing elements dispersed in the binder, the vitreous binder includes between 40% and 60% by weight of bismuth oxide Bi | 08-29-2013 |
Patent application number | Description | Published |
20090263803 | MIRNAS DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS - The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous, and/or abnormal tissues, including but not limited to cervix, skin, colon, breast, bladder, esophagus, liver, ovary, prostate, lung, pancreas, thyroid, kidney, stomach, testicle, uterus, spleen, tongue, brain, thymus, trachea and/or small intestine. In certain apsects, differential miRNA expression is initially determined by comparing miRNA expression between a normal tissue and cancer negative lymph node (LNneg), a normal tissue and a cancer positive lymph node (LNpos), a cancerous tissue and LNneg and/or LNpos, LNneg and LNpos. The methods of the invention are used to identify the presence or absence of non-lymphoid cells from other organs or tissues, and/or metastatic cancer cells present in lymph nodes. | 10-22-2009 |
20140141423 | miRNAs Differentially Expressed in Lymph Nodes from Cancer Patients - The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous, and/or abnormal tissues, including but not limited to cervix, skin, colon, breast, bladder, esophagus, liver, ovary, prostate, lung, pancreas, thyroid, kidney, stomach, testicle, uterus, spleen, tongue, brain, thymus, trachea and/or small intestine. In certain aspects, differential miRNA expression is initially determined by comparing miRNA expression between a normal tissue and cancer negative lymph node (LNneg), a normal tissue and a cancer positive lymph node (LNpos), a cancerous tissue and LNneg and/or LNpos, LNneg and LNpos. The methods of the invention are used to identify the presence or absence of non-lymphoid cells from other organs or tissues, and/or metastatic cancer cells present in lymph nodes. | 05-22-2014 |
Patent application number | Description | Published |
20100183752 | Foamable Compositions - A propellant-free foamable transparent composition, foamable by mixing with air or by hand rubbing, comprises a water-immiscible oil composition comprising at least one water-immiscible oil, which may be a mineral oil or vegetable oil, a siloxane resin foam stabiliser which is miscible in the water-immiscible oil composition to form a transparent liquid, and potentially a siloxane resin solubilising agent. The composition may be used for cosmetic applications. | 07-22-2010 |
20120107256 | Personal Care Emulsions Comprising Waxy Materials And Organopolysiloxanes - The invention provides an aqueous emulsion for use in a personal care, health care or household care composition. This emulsion comprises at least 1% by weight of a waxy material having a melting point of at least 10.5° C. and at least 1% by weight of an organopolysiloxane which is not miscible with the waxy material. The emulsion also contains an oil having a melting point below 10° C., the oil being miscible with the waxy material when melted and being present in a weight ratio of oil to waxy material in the range 5:95 to 95:5. This permits to obtain stable emulsion at low temperature. | 05-03-2012 |
20140234247 | Aminofunctional Organosiloxanes - Aminofunctional silicone compositions are disclosed comprising: an organopolysiloxane having an average formula of (CH | 08-21-2014 |
20140294746 | Aminofunctional Silicone Emulsions - Aqueous silicone emulsions are disclosed comprising: A) an aminofunctional organopolysiloxane, B) a quaternary ammonium surfactant having a formula R | 10-02-2014 |
20140308229 | Aminofunctional Silicone Emulsions For Fiber Treatments - Methods for treating fibers are disclosed with aqueous silicone emulsions comprising: A) an aminofunctional organopolysiloxane, B) a quaternary ammonium surfactant having a formula R | 10-16-2014 |
Patent application number | Description | Published |
20090304614 | Use of Polyunsaturated Compounds as Whitening Agents - The invention concerns the cosmetic or dermatological use of at least one compound of formula (I), wherein: R | 12-10-2009 |
20100240754 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY - The present invention relates to drugs consisting of unsaturated fatty amino-acid derivatives of the general formula (I), and to their pharmaceutically acceptable acid addition salts, in which: X is oxygen or NH, Rn are independently hydrogen or a (C | 09-23-2010 |
20110230557 | POLYUNSATURATED FATTY ACID AND DIOL ESTER AS AN ANTI-ACNE AGENT - The present invention relates to compounds of the following formula (I): where n is an integer between 1 and 15, m is 0, 1, 2 or 3, and R is the hydrocarbon chain of a polyunsaturated fatty acid selected from among omega 3 and omega 6, as well as to pharmaceutical or cosmetic compositions containing same, to a method for preparing and using same, in particular for treating acne and seborrhoeic dermatitis. | 09-22-2011 |
20120076744 | UNSATURATED FATTY ACID MONOESTERS AND DIESTERS ON ASCORBIC ACID AND COSMETIC USES THEREOF - The present invention relates to a compound with the following general formula (I): | 03-29-2012 |
20140030200 | PEPTIDYL ARGININE DEIMINASE 1 AND/OR 3 ACTIVATOR COMPOUNDS IN THE EPIDERMIS AND USES THEREOF - The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis. | 01-30-2014 |
20140315950 | NEW LIPOGENESIS INHIBITOR COMPOUNDS - The present invention relates to Formula (I), wherein—if X=NH, each of R | 10-23-2014 |
Patent application number | Description | Published |
20080227826 | Inhibitors of Histone Deacetylase - The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. One aspect of the invention provides compounds of formula (1): | 09-18-2008 |
20110021771 | INHIBITORS OF HISTONE DEACETYLASE - This invention relates to compounds and methods for the inhibition of HDAC enzymatic activity. More particularly, the invention provides for compounds of formula (I), (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein L, M, n, R, W, X and Y are as defined in the specification. | 01-27-2011 |
20110212965 | Inhibitors of Histone Deacetylase - The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. One aspect of the invention provides compounds of formula (1): | 09-01-2011 |
20140045850 | INHIBITORS OF HISTONE DEACETYLASE - This invention relates to compounds and methods for the inhibition of HDAC enzymatic activity. More particularly, the invention provides for compounds of formula (I), (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein L, M, n, R, W, X and Y are as defined in the specification. | 02-13-2014 |
Patent application number | Description | Published |
20080278111 | Method for charging a battery of an autonomous system - In an autonomous system, the method for charging a power storage element from a generator comprises temperature measurement, with switching from a first charging mode to a second charging mode in which the voltage is regulated by the temperature. The first charging mode is charging at regulated current to a maximum current value which is a function of the state of charge of the power storage element and of the temperature of the power storage element. Switching is performed when the voltage at the terminals of the power storage element reaches a preset threshold value, itself a function of the value of the current and temperature of the power storage element. | 11-13-2008 |
20100066309 | Method for pulsed charging of a battery in an autonomous system comprising a supercapacitance - The autonomous system comprises an intermittent power source delivering a direct current. A supercapacitance is connected in parallel with the battery and the power source respectively via a first switch and a second switch. Charging of the battery comprises pulsed current charging managed by a control circuit. During a current pulse, the amplitude of the current and the amplitude of the voltage increase at the terminals of the battery are measured. The dynamic internal resistance of the battery is determined from said amplitudes. A maximum acceptable current threshold is determined according to a maximum voltage threshold, to said dynamic internal resistance and to the no-load voltage at the battery terminals. At the next current pulse, the value of the charging current is limited by controlling the closing time of the second switch. | 03-18-2010 |
20100085063 | METHOD OF DIAGNOSING DEFECTIVE ELEMENTS IN A STANDALONE SYSTEM, POWERED BY AN INTERMITTENT POWER SOURCE - The diagnostic method applies to a standalone system including a generator, a power regulator and a power storage element. The method includes comparison of the effective charging power or current of the power storage element respectively with a predefined power or current threshold. If the effective charging power or current is lower than said threshold, the power storage element is disconnected. An abnormal behavior is then detected either by comparing the effective charging power with the smaller of the values representative of the theoretical charging power of the power storage element and of the maximum power able to be delivered by the generator and comparing the effective and theoretical charging voltages, or by comparing the effective and theoretical charging currents. | 04-08-2010 |
20120212173 | MANAGEMENT OF THE RECHARGING OF A SET OF BATTERIES - Method for managing the recharging of at least one battery, characterized in that it comprises a transmission of a desired charge level (C | 08-23-2012 |
20120212184 | METHOD FOR CHARGING OR DISCHARGING A BATTERY IN ORDER TO DETERMINE THE END OF CHARGING OR DISCHARGING ON THE BASIS OF MEASUREMENTS OF CURRENT AND TEMPERATURE - The method for charging or discharging a battery comprises measurement of the voltage at the terminals of the battery and comparison of the measured voltage with an end of charging or discharging voltage threshold. The method also comprises measurement of a temperature representative of the temperature of the battery and measurement of the current flowing in the battery to form a pair of measurements. The voltage threshold is then determined according to the pair of measurements. Charging or discharging of the battery is stopped when the voltage threshold is reached. | 08-23-2012 |
20140159674 | Method for Monitoring a Li-ion Battery and Monitoring Device for the Implementation Thereof - Method for monitoring an electrochemical cell or a battery ( | 06-12-2014 |
20150082617 | PROCESS FOR CHARGING A LEAD BATTERY TAKING INTO ACCOUNT ITS OXIDATION, PROCESS FOR GENERATING A NOMOGRAM FOR THE CHARGING PROCESS, DEVICE ASSOCIATED WITH THE CHARGING PROCESS, RECORDING MEDIUM AND COMPUTER PROGRAM WHICH ARE ASSOCIATED WITH THE CHARGING PROCESS - The process for charging a lead battery comprises an initialisation phase (E1), during which a value representative of an amount of lead oxide of the negative active material of the battery is determined, and a charging phase (E2), the duration of which is determined as a function of the value representative of amount of lead oxide. | 03-26-2015 |
Patent application number | Description | Published |
20090029393 | METHOD FOR PREPARING ANTIBODIES SELECTIVE FOR ACTIVATING FC RECEPTORS - The present invention relates to a method for preparing an antibody selective for activating antibody Fc region receptors (FcRs) comprising an ITAM motif or motifs (immunoreceptor tyrosine-based activation motif), comprising the steps of obtaining monoclonal antibodies from a hybridoma, from a heterohybridoma or from any animal, plant or human cell line, replacing each of the His 310 and His 435 residues (Cabat numbering) of the Fc region of said antibody with a residue chosen from lysine, alanine, glycine, valine, leucine, isoleucine, proline, methionine, tryptophan, phenylalanine, serine or threonine, and then selecting the antibodies for which the binding to inhibitory FcRs comprising ITIM motifs (immunoreceptor tyrosine-based inhibition motif) is decreased by at least 30%, preferably by at least 50%, 70%, 80% or else by at least 90% relative to the same antibody having a natural Fc region. The present invention also relates to the use of an antibody derived from the method of the invention in the production of a medicament for use in particular in the treatment of cancer and of infectious pathologies. | 01-29-2009 |
20090081216 | TREATMENT OF PATHOLOGIES WHICH ESCAPE THE IMMUNE RESPONSE, USING OPTIMIZED ANTIBODIES - The invention relates to the use of potimised human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies having a strong affvinity for receptor CD16 of the effector cells of the immune system and being able to induce the secretion of cytokines and interleukins, in particular 1“IFN? Or 1” IL2, for the treatment of pathologies for which the target cells only express a low antigenic density and in which the effector cells can only be recruited in small quantities. | 03-26-2009 |
20100303826 | Use of ADCC-Optimized antibodies for treating weak patients - The invention concerns the use of human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies bringing about a high ADCC activity as well as a high secretion of cytokines and interleukins, for treating underpopulations of so-called weak-response patients exhibiting CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphism. | 12-02-2010 |
20120009188 | OPTIMIZED FC VARIANTS - A variant of a parent polypeptide including an Fc region, which variant exhibits increased binding to FcRn as compared to the parent polypeptide and includes at least one amino acid modification in the Fc region. | 01-12-2012 |
20140017243 | USE OF ADCC-OPTIMIZED ANTIBODIES FOR TREATING WEAK PATIENTS - The invention concerns the use of human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies bringing about a high ADCC activity as well as a high secretion of cytokines and interleukins, for treating underpopulations of so-called weak-response patients exhibiting CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphism. | 01-16-2014 |
20140378663 | FC VARIANTS WITH REDUCED EFFECTOR FUNCTIONS - A method for producing a variant of a parent polypeptide including a Fc region, which variant exhibits reduced binding to the protein C1q and to at least one receptor Fcgγ R as compared to the parent polypeptide. | 12-25-2014 |
Patent application number | Description | Published |
20090130251 | DUAL COATED CONFECTIONERY PRODUCT - The present invention is directed generally to dual coated compositions for soft confectionery compositions and products containing the same. More particularly, the present invention relates to a non-particulate coating and a particulate coating for candy compositions where the particulate coating can include an acid blend in particulate form. | 05-21-2009 |
20100330247 | FOAMED CANDY - The present invention provides foamed candy compositions and methods for making foamed candy compositions. The foamed candy composition comprises a foam which comprises a sugar or a sugar substitute, a structuring agent and a fat or acid, and is characterised in that the fat or acid is associated with a carrier material. Examples include foamed candies comprising spray dried fruit powder, encapsulated malic acid, cocoa powder or chocolate crumb. | 12-30-2010 |
20110123670 | COMESTIBLE PRODUCTS - The invention relates to a comestible product comprising one or more zones, wherein galactose is the primary sweetener in at least one zone of the comestible product, and whereby the present of galactose stimulates a mouth-watering effect for at least part of the time that the comestible is in the mouth. A method of improving the mouth-watering effect of a comestible comprising incorporating galactose into the comestible is also described, as is a method of preparing the comestible comprising the incorporation of galactose. Also considered is the use of the comestible in the treatment of xerostomia. | 05-26-2011 |
Patent application number | Description | Published |
20090013400 | Method of filtering undesirable streams coming from a terminal presumed to be malicious - A method of filtering undesirable streams coming from a terminal ( | 01-08-2009 |
20090262652 | METHOD OF EVALUATING THE RELIABILITY OF A ROUTE IN A COOPERATIVE NETWORK - The invention relates to a method of evaluating the reliability of a route in a cooperative network for transmitting packets of data between a source node and a destination node of the network. It includes, on reception by the destination node of a message indicating a route between the two nodes:
| 10-22-2009 |
20140189868 | METHOD FOR DETECTING INTRUSIONS ON A SET OF VIRTUAL RESOURCES - A method for detecting intrusions on a set of virtual resources in a computer system including at least one physical machine hosting the set of virtual resources. The method includes: calculating an intrusion detection itinerary defined by a sequence of virtual resources from the set, the virtual resources being integrated and arranged in the sequence on the basis of respective vulnerability criticality levels assigned to the virtual resources of the set; and carrying out an intrusion detection operation, following the calculated itinerary. | 07-03-2014 |
20140223556 | Method for Detecting Attacks and for Protection - A method is provided for attack detection and protection of a set of virtual machines in a system, which includes at least one first host server hosting said set of virtual machines. The method includes: receiving an attack detection message regarding a virtual machine, triggering a first migration of the virtual machine from the first host server toward a security system, and receiving an attack treatment message regarding the migrated virtual machine. | 08-07-2014 |
Patent application number | Description | Published |
20100108676 | BOX WITH RETRACTABLE LID FOR COSMETIC OR TOILETRY PRODUCTS - A box for cosmetic or toiletry products includes a body having a bottom and a free edge | 05-06-2010 |
20110147399 | CASE FOR COSMETIC OR BODY HYGIENE PRODUCT HAVING A RETRACTABLE HINGE - A case for a cosmetic or body hygiene product comprises a body having a bottom and a free edge | 06-23-2011 |
20120276329 | DECORATED CARD - A decorated card having at least one leaf, and a cutout formed in the leaf and defined by a cutout outline. The card is characterized by the fact that it has at least two threads extending under tension across the cutout outline, and a plurality of spangles, the spangles being held suspended from each of the threads under tension so as to cover at least part of the area defined by the cutout outline. A manufacturing method is also provided. | 11-01-2012 |
20140212606 | METHOD AND EQUIPMENT FOR MANUFACTURING A THIN, HOLLOW GLASS ITEM - The invention relates to a method, comprising: feeding at least one molten-glass parison into a parison mold; forming, in the parison mold, a blank of an item from said at least one parison; transferring the blank of the item into a finishing mold; and forming the item in the finishing mold. While forming the item in the finishing mold, excess glass is directed out of the base of the item so as to form a convex bulge, and said bulge is removed such that the thickness of the base of the item is substantially constant. | 07-31-2014 |
Patent application number | Description | Published |
20100307650 | TREAD FOR TIRE INCLUDING GUM BLOCKS WITH NOTCHES - Tread for a tire provided with a running surface intended to come into contact with the roadway when running, this tread comprising a plurality of blocks of mean axis XX′ intersecting the running surface of the tread, each block, including a side wall that makes a full circuit of the block about the axis XX′. This side wall intersects the running surface at an edge with a closed geometric outline, this edge delimiting a contact surface via which the block makes contact with the roadway. The side wall of the block and the opposite wall delimit an incision, the blocks being provided on their lateral surface with at least one notch having a depth measured perpendicular to the lateral surface of the block and a width measured parallel to the lateral face of the block, the at least one notch at least partially making a circuit of the block about the axis XX′, that is to say at least over 180 degrees. | 12-09-2010 |
20120000585 | Tread with Blocks - Tire tread comprising a plurality of rubber pads, each rubber pad being delimited by an incision of depth and of closed contour, this tread having:
| 01-05-2012 |
20130139939 | METHOD OF DESIGNING A TIRE, AND TIRE - Method of designing a tire for the steered axle of a heavy goods vehicle, having a nominal sidewall height F, having a tread in the new state having a maximum total width Lo for maximum contact with the ground and provided with at least four circumferential grooves each extending between the tread surface and a groove bottom, these grooves delimiting three intermediate ribs and two edge ribs axially bounding the tread, each edge rib having two lateral walls, one of which, known as the internal lateral wall, having a height PREp measured with respect to the bottom of the groove delimiting the edge rib, this internal lateral wall having, when viewed in section on a plane containing the axis of rotation, an inclination DEp, each edge rib having a width LEp greater than the width of each of the intermediate ribs, by iteratively determining values for the dimensions LEp, PREp and DEp that satisfy the following relationship:
| 06-06-2013 |
Patent application number | Description | Published |
20090208085 | METHOD FOR PROCESSING IMAGES OBTAINED BY TOMOSYNTHESIS AND ASSOCIATED DEVICE - A processing method for images obtained by tomosynthesis comprising acquisition of a plurality of 2D projection images of a region of interest of a patient; reconstruction of a 3D digital image from the acquired 2D projection images. An embodiment of the method is characterised in that it comprises: detection of an object in the reconstructed image; estimation of a thickness limit characteristic of a contrast default of the voxels for a diameter of the object; estimation of the thickness of the object; comparison of the thickness of the object to the thickness limit; and in that if the thickness of the object is less than the thickness limit, the method further comprises application at least to the voxels of the object in the reconstructed image of a multiplicative corrective factor equal to the ratio between the thickness limit and the thickness of the object. | 08-20-2009 |
20090304253 | METHOD OF PROCESSING RADIOLOGICAL IMAGES, AND, IN PARTICULAR, MAMMOGRAPHIC IMAGES - A method of processing a radiological image of an organ. The method may comprise generating a recombined image (R) from at least one previously acquired low energy image (L) and one high energy image (H) of a portion of the organ. The recombined image comprises a background and one or more areas corresponding to the presence of a contrast medium in the organ. The method may further comprise correcting the recombined image (R) by compensating (C) for the nonuniformities present in the background to obtain a compensated recombined image in which the background has a substantially uniform grey level. | 12-10-2009 |
20120106697 | METHOD FOR ESTIMATING AND CORRECTING SCATTERING IN MAMMOGRAPHY - A method for correcting at least one image of an object obtained with a mammography system is provided. The method comprises: acquiring a pre-exposure image of an object to determine the acquisition conditions for main images, the pre-exposure image comprising regions corresponding to the projection of radio-opaque elements, wherein a mask comprising radio-opaque elements is in an acquisition position; acquiring the main images resulting from the passing through the object of X-rays at higher doses than the dose used for acquisition of the pre-exposure image, wherein the mask comprising radio-opaque elements is in a retracted position; extracting regions from the pre-exposure image which correspond to the projection of radio-opaque elements; and determining the contribution of X-ray scatter at every point of the at least one image of the object, on the basis of the regions extracted from the pre-exposure image. | 05-03-2012 |
20130044861 | METHOD FOR ACQUIRING MORPHOLOGY OF A BREAST - An imaging method performed by a device comprising an X-ray emitting source, a receiver positioned facing the source, and a support on which a subject or organ to be imaged is positioned, the method comprises defining a first set of orientations of the source and a second set of orientations of the source, and acquiring images at the defined orientations of the source, wherein if the first set of orientations comprises an orientation that the second set of orientations does not comprise, only one image is acquired at the orientation, and if both the first set of orientations and the second set of orientations comprise the same orientation, at least two images are acquired at distinct acquisition parameters at the orientation. | 02-21-2013 |
Patent application number | Description | Published |
20090176212 | Method for Fixing a Supercoiled DNA and the Use for Analyzing the DNA Repair - A method for fixing a supercoiled DNA consists in deposing a supercoiled DNA sample on the surface of a porous polymer film, in fixing said supercoiled DNA therein by a passive diffusion, in obtaining a support by the inventive method and in using said support for analysing the DNA distribution. | 07-09-2009 |
20120283379 | SILICA PARTICLE INCLUDING A MOLECULE OF INTEREST, METHOD FOR PREPARING SAME AND USES THEREOF - What is provided includes a nanoparticle of porous silica, incorporating at least one molecule of interest, the silica network inside said nanoparticle being functionalized by at least one group capable of setting up an ionic and/or hydrogen non-covalent bond with the molecule of interest, whereby the molecule(s) of interest is(are) linked to the silica network solely by non-covalent bonds. In addition, a method for preparing said silica particle and uses thereof is provided. | 11-08-2012 |
20150031580 | METHOD FOR THE QUANTITATIVE ASSESSMENT OF GLOBAL AND SPECIFIC DNA REPAIR CAPACITIES OF AT LEAST ONE BIOLOGICAL MEDIUM, AND THE APPLICATIONS THEREFOR - A method for quantitative assessment of base excision repair (BER) and nucleotide excision repair (NER) DNA repair capacities of at least one cellular extract, which method entails: a) preparing a range of plasmids with at least one physical or chemical treatment or both and recovering a supercoiled fraction of each of said plasmids, b) characterizing the lesions present on each of the plasmids of the range of plasmids; c) depositing the plasmids of the range of plasmids, and at least one supercoiled control plasmid without lesions onto a single solid support, according to a pre-established configuration A, so as to form a functionalized support divided into different zones A1 to Ax, corresponding to an integer equal to the number of cellular extracts to be simultaneously tested, each zone containing supercoiled plasmids treated with at least one physical or chemical treatment that induces a lesion acted upon by BER mechanisms, and at least one other zone containing supercoiled plasmids treated with at least one physical or chemical treatment that induces a lesion acted upon by NER mechanisms; d) incubating the functionalized support obtained in step c) with various repair solutions, each of which contains at least one cellular extract from a subject, and labeled nucleotide phosphates; e) washing the functionalized support at least once; f) directly or indirectly measuring the signal produced by the labeled nucleotide triphosphate incorporated into the DNA during the repair reaction in step d), in each of the different and pre-established zones A | 01-29-2015 |
Patent application number | Description | Published |
20100233250 | VACCINE - The present invention provides a vaccine or immunogenic composition comprising: an immunogenic SARS coronavirus S (spike) polypeptide, or a fragment or variant thereof; and an adjuvant comprising a lipopolysaccharide, a saponin and a liposome. | 09-16-2010 |
20110065089 | NOVEL STRAIN OF SARS-ASSOCIATED CORONAVIRUS AND APPLICATIONS THEREOF - The invention relates to a novel strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from a sample collected in Hanoi (Vietnam), reference number 031589, nucleic acid molecules originating from the genome of same, proteins and peptides coded by said nucleic acid molecules and, more specifically, protein N and the applications thereof, for example, as diagnostic reagents and/or as a vaccine. | 03-17-2011 |
20120082693 | USE OF PROTEINS AND PEPTIDES ENCODED BY THE GENOME OF A NOVEL SARS-ASSOCIATED CORONAVIRUS STRAIN - The invention relates to the use of proteins and peptides coded by the genome of the isolated or purified strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from sample reference number 031589 and, in particular, to the use of protein S and the derivative antibodies thereof as diagnostic reagents and as a vaccine. | 04-05-2012 |
Patent application number | Description | Published |
20090197344 | METHOD FOR THE PREDICTION OF VASCULAR EVENTS AND THE DIAGNOSIS OF ACUTE CORONARY SYNDROME - The present invention relates to a method for the prognosis of a vascular event or the diagnosis of ACS in a patient suspected of being at risk for a vascular event or condition, said patient presenting:
| 08-06-2009 |
20100209939 | BNP(1-32) EPITOPE AND ANTIBODIES DIRECTED AGAINST SAID EPITOPE - The present invention relates to a polypeptide carrying a human BNP(I-32) epitope according to Formula (I): a | 08-19-2010 |
20120034604 | USE OF BASIC PROLIN-RICH LACRIMAL GENE PRODUCTS, SUCH AS OPIORPHIN, AS A BIOMARKER - The present invention relates to the use of Basic Prolin-rich Lacrimal protein (BPLP) gene products, such as Opiorphin, for establishing a prognosis, a diagnosis or the monitoring of a pathological state or of treatment efficacy in a subject and the related method of use. | 02-09-2012 |
20140193843 | USE OF BASIC PROLIN-RICH LACRIMAL GENE PRODUCTS, SUCH AS OPIORPHIN, AS A BIOMARKER - The present invention relates to the use of Basic Prolin-rich Lacrimal protein (BPLP) gene products, such as Opiorphin, for establishing a prognosis, a diagnosis or the monitoring of a pathological state or of treatment efficacy in a subject and the related method of use. | 07-10-2014 |
Patent application number | Description | Published |
20100273793 | 6-ARYL/HETEROALKYLOXY BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, APPLICATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS c-MET INHIBITORS - The disclosure relates to compounds of formula (I): | 10-28-2010 |
20100298315 | NOVEL 6-TRIAZOLOPYRIDAZINESULFANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND APPLICATION AS MEDICAMENTS AND PHARMNACEUTICAL COMPOSITIONS AND NOVEL USE AS MET INHIBITORS - The disclosure relates to compounds of formula (I): | 11-25-2010 |
20110257171 | NOVEL IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF, USE THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS MET INHIBITORS - The invention relates to the novel products of formula (I): in which: Ra is H, Hal, aryl or heteroaryl, which are optionally substituted; Rb is H, Rc, —COORc-CO-Rc or —CO—NRcRd; where Rc is alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl, all optionally substituted; Rd is H, alk or cycloalkyl; these products being in all the isomer forms and the salts, as medicaments, in particular as MET inhibitors. | 10-20-2011 |
20110263594 | NOVEL TRIAZOLO(4,3-A)PYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE, IN PARTICULAR AS MET INHIBITORS - The invention relates to the novel products of formula (I): in which: Ra represents H, Hal, aryl or heteroaryl, which is optionally substituted; Rb represents H, Rc, —COORc-CO-Rc or —CO—NRcRd; where Rc represents alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl, all optionally substituted; Rd represents H, alk or cycloalkyl; these products being in all the isomer forms and the salts, as medicaments, in particular as MET inhibitors. | 10-27-2011 |
20120040987 | DERIVATIVES OF 6-(6-NH-SUBSTITUTED-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLES AND BENZIMIDAZOLES, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS - The invention relates to novel products of the formula (I) where: (II) is a single or double bond; Rb is a hydrogen or fluorine atom; Ra is a NH-Rc radical in which Rc is an optionally substituted heterocycloalkyl, aryl, heteroaryl or -alkylcycloalkyl radical; X is S, SO, or SO2; A is NH or S; W is H, alkyl, or COR with R being cycloalkyl; alkyl; alkoxy; O-phenyl; —O— (CH2)n-phenyl with n=1 to 4; or NR1R2 with R1 being H or alk and R2 is H, cycloalkyl or alkyl; or R1, R2 form a cycle together with N optionally containing O, S, N and/or NH; all of said radicals being optionally substituted; wherein said products can be in any isomer or salt form, and can be used as drugs, in particular as MET inhibitors. | 02-16-2012 |
20120165326 | DERIVATIVES OF 6-(6-SUBSTITUTED-TRIAZOLOPYRIDAZINE-SULFANYL) 5-FLUORO BENZOTHIAZOLES AND 5-FLUORO BENZIMIDAZOLES, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS - The invention relates to novel products of the formula (I) where: (II) is a single or double bond; F is a fluorine atom, Ra is H, HaI, alkoxy, O-cycloalkyl, —O— heterocycloalkyl; —NH-heterocycloalkyl, heteroaryl, phenyl, NHCOalk NHCOcycloalk or NR1 R2; X is S, SO or SO2, A is NH or S; W is H, alkyl, or COR with R being cycloalkyl; alkyl optionally substituted by NR3R4, alkoxy, hydroxy, phenyl, heteroaryl or heterocycloalkyl; alkoxy optionally substituted by NR3R4, i.e. a O—(CH2)n-NR3R4 radical, an O-phenyl or an O—(CH2)n-phenyl radical, with phenyl optionally substituted and n=1 to 4; or the NR1 R2 radical; R1 is H or alk and R2 is H, cycloalkyl or alkyl; R3 and R4 are H, alk, cycloalkyl, heteroaryl or phenyl; R1, R2 and/or R3, R4 form a cycle together with N optionally containing O, S, N and/or NH; heterocycloalkyl, heteroaryl and phenyl and cycles all being optionally substituted; wherein said products can be in any isomer or salt form, and can be used as drugs, in particular as MET inhibitors. | 06-28-2012 |
20140005189 | NOVEL 6-TRIAZOLOPYRIDAZINE SULFANYL BENZOTHIAZOLE DERIVATIVES AS MET INHIBITORS | 01-02-2014 |
Patent application number | Description | Published |
20080253200 | Reading of the State of a Non-Volatile Storage Element - A method for reading of the state of a non-volatile memory element, comprising adjusting including conditioning the frequency of a first oscillatory to the state of this element, and comparing the frequency of the first oscillator with the predetermined frequency of a second oscillator, selected between two possible frequency values for the first oscillator, according to the state of the storage element. | 10-16-2008 |
20090073759 | Device for protecting a memory against attacks by error injection - A memory is secured against an error injection during the reading of a datum. The memory includes: means for reading a reference datum in the memory during a phase of reading a datum stored in the memory; means for comparing the reference datum read with an expected value; and means for generating an error signal if the datum read is different from the expected value. Application is provided particularly but not exclusively to the protection of memories integrated into smart cards. | 03-19-2009 |
20100135087 | READING OF THE STATE OF A NON-VOLATILE STORAGE ELEMENT - A method for reading of the state of a non-volatile memory element including conditioning the frequency of a first oscillator to the state of this element, and comparing the frequency of the first oscillator with the predetermined frequency of a second oscillator, selected between two possible frequency values for the first oscillator, according to the state of the storage element. | 06-03-2010 |
20110128030 | MONITORING OF THE ACTIVITY OF AN ELECTRONIC CIRCUIT - A method and a device for monitoring a digital signal, wherein a first P-channel MOS transistor is placed in degradation conditions of negative bias temperature instability type during periods when the signal to be monitored is in a first state; a first quantity representative of the saturation current of the first transistor is measured when the signal to be monitored switches to a second state; and a detection signal is switched when this first quantity exceeds a threshold. | 06-02-2011 |
20120030443 | PROTECTION OF SECRET KEYS - A method for protecting at least first data of a non-volatile memory from which the extraction of this first data is triggered by the reading or the writing, by a processor from or into the memory, of second data independent from the first data, said first data being provided to a circuit which the processor cannot access. | 02-02-2012 |
20140138686 | PROTECTION OF AN INTEGRATED CIRCUIT AGAINST ATTACKS - An integrated circuit, including: a semiconductor substrate of a first conductivity type; a plurality of regions of the first conductivity type vertically extending from the surface of the substrate, each of the regions being laterally delimited all along its periphery by a region of the second conductivity type; and a device for detecting a variation of the substrate resistance between each region of the first conductivity type and an area for biasing the substrate to a reference voltage. | 05-22-2014 |