Cleator
Edward Cleator, Cambridge GB
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20100099923 | Process for the Preparation of Bicyclo[3.1.0]Hexanols - A process for the preparation of a the formula (I): which process comprises the intramolecular cyclopropanation of an epoxide of me formula (II); in the presence of 0.05 to 0.75 equivalents of a secondary amine base and at least one equivalent of an alkyl lithium base, wherein R R | 04-22-2010 |
20100174091 | Process for the preparation of tetrazolytetrahydrocyclopentapyrazoles - A process for the preparation of a compound of formula (I), or a salt, hydrate or solvate thereof; wherein R | 07-08-2010 |
20130331379 | PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST - The present invention is directed to processes for preparing a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is further directed to crystalline forms of this diazepane compound and pharmaceutical compositions thereof. | 12-12-2013 |
20140242645 | PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES - The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions. | 08-28-2014 |
20150087832 | PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES - The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. | 03-26-2015 |
Edward Cleator, Hoddesdon GB
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20140243519 | METHODS AND INTERMEDIATES FOR PREPARING MACROLACTAMS - The present invention includes compounds useful as intermediates in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing macrolactams. One use of the methods and intermediates described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applica | 08-28-2014 |
Edward Cleator, Whtittlesford GB
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20150038707 | PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS - Methods for preventing pest infestations are disclosed. In some embodiments, the methods for preventing infestations involve use of pyrethroid insecticides or the stereoisomers or salts thereof. | 02-05-2015 |
Iain G.m. Cleator, Vancouver CA
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20080300575 | Anal ointment applicator - Medicinal applicator suitable for delivering medicinal material in a measured dose and concentration to a body cavity, having an elongate support body with an external surface and a blunt distal end to facilitate insertion into a body cavity and a support element receiving zone located towards the distal end for receiving the support element. The support element receiving zone is configured to receive a correspondingly shaped support element for carrying medicinal material, whereby upon insertion of the elongate body into the body cavity, medicinal material supported on the support element located in the receiving zone is released to a desired location within the cavity. | 12-04-2008 |
20140121679 | ELASTIC BAND LIGATION DEVICE AND METHOD FOR TREATMENT OF HEMORRHOIDS - Elastic band ligation device for treating hemorrhoids and treatment method are provided. The device includes an inner tubular member for retaining an elastic band over the front end. The inner tubular member is arcuate and is insertable into the rectum of a patient. A plunger in the tubular member when pulled generates a suction for drawing hemorrhoidal tissue into the inner tubular member through the front end. A plastic outer tubular pusher sleeve has an arcuate configuration corresponding to the arcuate inner tubular member to provide a limited friction fit over the inner tubular member. The pusher sleeve has a thumb pusher to allow the outer tubular pusher sleeve to be pushed towards the front end of the inner tubular member and release the elastic band from the front end of the inner tubular member to engage hemorrhoidal tissue extending through the opening in the inner tubular member. | 05-01-2014 |
Lain G.m. Cleator, Vancouver CA
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20100063517 | Elastic band ligation device and method for treatment of hemorrhoids - An elastic band ligation device for treatment of hemorrhoids and method of treating hemorrhoidal tissue are provided including a plastic inner tubular member for retaining a stretched elastic band over the front end thereof. The inner tubular member has an arcuate configuration extending along at least a portion of the length thereof for a sufficient distance for insertion into the rectum of a patient. A plunger is provided in the tubular member with a handle to allow the operator to pull the plunger and generate a suction for drawing hemorrhoidal tissue into the inner tubular member through the opening at the front end. A plastic outer tubular pusher sleeve is provided having an arcuate configuration corresponding to the arcuate configuration of the inner tubular member to provide a limited friction fit over the inner tubular member. The pusher sleeve is provided with a thumb pusher for the operator to push the outer tubular pusher sleeve towards the front end of the inner tubular member and release the elastic band from the front end of the inner tubular member to engage hemorrhoidal tissue extending through the opening in the inner tubular member. The invention also provides a method of treating hemorrhoidal tissue and an elastic band fabricated from a non-latex material. | 03-11-2010 |