Patent application number | Description | Published |
20080312148 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 12-18-2008 |
20100099612 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 04-22-2010 |
20100129904 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 05-27-2010 |
20100303759 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 12-02-2010 |
Patent application number | Description | Published |
20110224300 | USE OF POTASSIUM 2-(a- HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA - The present invention discloses the use of potassium 2-(α-hydroxypentyl) benzoate in the manufacture of medicaments for preventing, relieving or treating senile dementia diseases or symptom, and for relieving oxidative stress injury in brain tissue, increasing neural function of choline, protecting neuron and/or raising the content of brain nerve growth factor. The present invention also discloses a pharmaceutical composition comprising potassium 2-(α-hydroxypentyl) benzoate in prophylactically or therapeutically effective dose, optionally, a pharmaceutically acceptable carrier and/or adjuvant. | 09-15-2011 |
20140111759 | Composite Comprising a Polymer and a Blue Phase Liquid Crystal, a Method for Preparing the Composite, and a Liquid Crystal Display Device Comprising the Composite - The present invention relates to a composite comprising a polymer and a blue phase liquid crystal (BPLC). The polymer is a crosslinked and non-liquid crystalline polymer, the BPLC is dispersed in said polymer, and the ratio of the polymer to the BPLC by weight (W | 04-24-2014 |
20140291579 | BLUE PHASE LIQUID CRYSTAL COMPOSITE MATERIAL AND LIQUID CRYSTAL DISPLAY CONTAINING THE SAME - This disclosure relates to a blue phase liquid crystal composite material formed by photopolymerization of material components comprising a parent blue phase liquid crystal, a photo-polymerizable monomer, a photoinitiator, and inorganic nanoparticles; and to a liquid crystal display comprising the blue phase liquid crystal composite material. The blue phase liquid crystal composite material has a low driving voltage, no electro-optical hysteresis, and rapid response time to an electric field. | 10-02-2014 |
20150315467 | BLUE PHASE LIQUID CRYSTAL COMPOSITE MATERIAL AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME - A blue phase liquid crystal composite material and a liquid crystal display comprising the same, can solve the problem of small Kerr constant of the current blue phase liquid crystal and the liquid crystal display comprising the same. The blue phase liquid crystal composite material of the present disclosure is produced by the photo polymerization of the components comprising: a parent blue phase liquid crystal, a benzyne compound, a chiral compound, a photo-polymerizable monomer, and a photoinitiator. The blue phase liquid crystal composite material of the present disclosure has the advantages of large Kerr constant, low voltage, high contrast, rapid response to electric field, good stability, and the like. | 11-05-2015 |
20150362787 | DISPLAY MODULE - The present disclosure provides a display module, comprising a light guide plate; a display panel arranged on one side of the light guide plate; a fixing element capable of being fixed on a peripheral edge of the display panel; a backboard arranged on one side of the light guide plate far away from the display panel; and a rubber frame arranged on the periphery of the light guide plate, wherein the rubber frame is connected and fixed to the backboard, and further engageably connected to the fixing element so as to fix the display panel. | 12-17-2015 |
Patent application number | Description | Published |
20120271381 | LARGE-PITCH COIL CONFIGURATIONS FOR A MEDICAL DEVICE - Techniques related to coils for medical device are disclosed. One example coil may comprise multiple filars, each being formed of a biocompatible beta titanium alloy having an elastic modulus ranging from 30 GigaPascals (GPa) to 90 GPa and comprising at least two elements from a group consisting of titanium, molybdenum, niobium, tantalum, zirconium, chromium, iron and tin. At least one of the multiple filars may be electrically insulated one from another. A structural body, such as a lead body, may carry the coil. One or more filars may carry a low-resistance core. | 10-25-2012 |
20120271385 | LOW IMPEDANCE, LOW MODULUS WIRE CONFIGURATIONS FOR A MEDICAL DEVICE - Techniques are disclosed related to wires that may be used within a medical device. According to one example, a wire may include a core formed of a material having a resistivity of less than 25 micro-ohm-cm and a layer of a biocompatible beta titanium alloy surrounding the core. As one example, the beta titanium alloy has an elastic modulus ranging from 30 GigaPascals (GPa) to 90 GPa and comprises at least two elements from a group consisting of titanium, molybdenum, niobium, tantalum, zirconium, chromium, iron and tin. In one embodiment, the core may be formed of silver, tantalum, a tantalum alloy, niobium, a niobium alloy, platinum, a platinum alloy, palladium, or a palladium alloy. In some examples, one or more wires may be incorporated into a coil or a cable and one or more such coils or cables may be carried by a medical device such as a medical electrical lead. | 10-25-2012 |
20120271386 | CABLE CONFIGURATIONS FOR A MEDICAL DEVICE - Techniques are disclosed related to cables that may be used within a medical device. According to one example, a cable may comprise multiple wires. Each wire may be formed of a biocompatible beta titanium alloy having an elastic modulus ranging from 30 GigaPascals (GPa) to 90 GPa and comprising at least two elements selected from a group of titanium, molybdenum, niobium, tantalum, zirconium, chromium, iron and tin. The cable may be heated to a stress-relieve temperature of the beta titanium alloy to allow the cable to retain a desired configuration while remaining ductile. The cable may be included within a medical device, such as a medical electrical lead. | 10-25-2012 |
20140130565 | LOW IMPEDANCE, LOW MODULUS WIRE CONFIGURATIONS FOR A MEDICAL DEVICE - Techniques are disclosed related to wires that may be used within a medical device. According to one example, a wire may include a core formed of a material having a resistivity of less than 25 micro-ohm-cm and a layer of a biocompatible beta titanium alloy surrounding the core. As one example, the beta titanium alloy has an elastic modulus ranging from 30 GigaPascals (GPa) to 90 GPa and comprises at least two elements from a group consisting of titanium, molybdenum, niobium, tantalum, zirconium, chromium, iron and tin. In one embodiment, the core may be formed of silver, tantalum, a tantalum alloy, niobium, a niobium alloy, platinum, a platinum alloy, palladium, or a palladium alloy. In some examples, one or more wires may be incorporated into a coil or a cable and one or more such coils or cables may be carried by a medical device such as a medical electrical lead. | 05-15-2014 |
20140142672 | WIRE CONFIGURATION AND METHOD OF MAKING FOR AN IMPLANTABLE MEDICAL APPARATUS - A filar includes an inner conductive core that is formed of a low-resistivity material such as silver having a resistivity of less than 20 μΩ per centimeter. A conductive coil is provided around the core to form a filar. This coil is formed of a biocompatible alloy or super alloy having an ultimate tensile strength (UTS) of between 150 kilo pounds per square inch (ksi) and 280 ksi at room temperature. Examples of such alloys include CoCrMo, CoFeCrMo, and CoFeNiCrMo. In one specific embodiment, the alloy is MP35N (CoNiCrMo), which may be low-titanium (“low-ti”) MP35N. One or more such filars may be included within a wire. This wire may be carried by an implantable medical apparatus such as a lead, lead extension, or catheter. The wire may electrically couple elements such as connector electrodes to conducting electrodes or sensors. | 05-22-2014 |
Patent application number | Description | Published |
20140275113 | CRYSTALLINE FORMS OF TRYOSINE KINASE INHIBITORS AND THEIR SALTS - The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof. | 09-18-2014 |
20150174124 | CRYSTALLINE FORMS OF TRYOSINE KINASE INHIBITORS AND THEIR SALTS - The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof. | 06-25-2015 |
20150218188 | COMPOSITIONS OF PROTEIN RECEPTOR TYROSINE KINASE INHIBITORS - The present invention relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same that are capable of inhibiting or antagonizing a family of receptor tyrosine kinases, Tropomysosin Related Kinases (Trk), in particular the nerve growth factor (NGF) receptor, TrkA. The invention further concerns the use of such compounds in the treatment and/or prevention of pain, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, or a disease, disorder or injury relating to dysmyelination or demyelination or the disease or disorder associated with abnormal activities of NGF receptor TrkA. | 08-06-2015 |
20160002182 | CRYSTALLINE FORMS OF TRYOSINE KINASE INHIBITORS AND THEIR SALTS - The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof. | 01-07-2016 |
Patent application number | Description | Published |
20140295891 | METHOD, SERVER AND TERMINAL FOR INFORMATION INTERACTION - It is provided a method, a server and a terminal for information interaction. One method for information interaction includes the following steps: obtaining, at a server, position information of a first terminal in a social network, direction information of the first terminal shooting a scene image, and an information search range corresponding to the first terminal; searching, at the server, for an information collection in the information search range corresponding to the first terminal in the social network according to the position information of the first terminal and the direction information of the first terminal shooting the scene image; and sending, at the server, the information collection to the first terminal so that the first terminal displays the information collection in the scene image shot by the first terminal. | 10-02-2014 |
20140333746 | METHOD AND APPARATUS FOR INQUIRING INFORMATION - A method and an information inquiring apparatus is provided. The method includes: acquiring facial image of a target user to be inquired when receiving query information request; querying social network service information of the target user matching with the facial image, based on the facial image of the target user; and outputting social network service information of the target user. The method and the information inquiring apparatus are configured to increase efficiency of information queries and improve intelligence of the SNS application. | 11-13-2014 |
20150058737 | METHOD AND APPARATUS FOR DISTRIBUTING CONTENT TO MULTIPLE DEVICES - An approach is provided distributing content to multiple devices. Specifically, a distribution module causes, at least in part, a rendering of at least one user interface for distributing content among at least one device and one or more other devices with connectivity to the at least one device. The distribution module then causes, at least in part, one or more segmentations of the at least one user interface, wherein the one or more segmentations are associated with the at least one device, respective one or more of the one or more other devices, or a combination thereof. Next, the distribution module determines one or more interactions with the at least one user interface, the one or more segmentations, or a combination thereof to cause, at least in part, a distribution of the content. | 02-26-2015 |
20150121260 | TERMINAL DEVICE AND METHOD FOR DESIGNING NETWORK APPLICATION PRODUCT - Terminal devices and methods for designing a network application product are provided. The terminal device includes a task starting interface, a graphical displaying interface, an inputting interface. The task starting interface is configured to receive a task starting instruction to obtain a plurality of first type e-cards having at least one dimensionality type. Each first type e-card contains graphic information corresponding to a dimensionality type and text information corresponding to the graphic information. The graphical displaying interface is configured to display the plurality of first type e-cards. The inputting interface is configured to receive an inputting instruction to select at least two first type e-cards from the plurality of first type e-cards. The inputting interface is further configured to receive context information generated by correlating information including the graphic information and the text information on the at least two first type e-cards. | 04-30-2015 |
Patent application number | Description | Published |
20150048863 | RECONFIGURABLE CIRCUIT AND DECODER THEREFOR - A digital decoder, used in a reconfigurable circuit, for decoding digital pulses includes a phase indicator module having inputs coupled to a reference pulse input and a data pulse input. The phase indicator module has timing information outputs that provide logic values indicative of rising and falling edges of pulses occurring on the reference pulse input and the data pulse input. A phase decoder module has inputs coupled to the timing information outputs, and outputs decoded binary data values. In operation, the phase decoder module compares at least two of the logic values at the timing information outputs with a signal representative leading and trailing edges of a pulse applied to one of the phase inputs to determine a pulse arrival order sequence on the phase inputs and thereby provide the decoded binary data values. | 02-19-2015 |
20150275600 | METHOD FOR SWEEPING SOLIDS OR DISPLACING A FLUID IN A WELLBORE - A method and system for removing solids or displacing a fluid from a wellbore wherein a plurality of resilient rubber-like flexible reticulated open cell foam elements are dispersed in a fluid and pumped through drill pipe and into the annulus between the wellbore and the drill pipe. In the annulus, the foam elements impact and dislodge solids such as proppants, gravels, drilled cuttings and other solids or a fluid to be displaced and the proppants, etc. or the fluid are carried by the fluid containing the foam elements back to the surface or a different location in the wellbore. At the surface, the fluid containing the foam elements and the proppants, etc., is carried to a shale shaker where the solids and the foam elements are separated from the fluid. The separated solids and foam are collected for disposal and, after adding new foam elements, the fluid can be recirculated down hole. | 10-01-2015 |