Liu, DE
Danni Liu, Stuttgart DE
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20100151502 | FUNCTIONAL EXPRESSION OF TRIACYLGYLCEROL LIPASES - The present invention relates to nucleic acids that code for triacylglycerol lipases, vectors comprising said nucleic acids, host cells comprising said nucleic acids or vectors, methods for the expression of triacylglycerol lipases in prokaryotes, methods for the detection and for the production of triacylglycerol lipases, triacylglycerol lipases obtainable thereby, and the use of triacylglycerol lipase-encoding nucleic acids, vectors and recombinant host cells for said methods. | 06-17-2010 |
20100273223 | New Calb Muteins and Their Use - A protein having acrylation activity having a polypeptide sequence derived from SEQ ID NO: 1 or NO:2 by introducing at least one of the following amino acid substitutions: L278A, L278V, W104F, T42A, S47A. | 10-28-2010 |
Fuwen Liu, Cottbus DE
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20120082312 | METHOD OF AUTHENTICATION AND SESSION KEY AGREEMENT FOR SECURE DATA TRANSMISSION, A METHOD FOR SECURELY TRANSMITTING DATA, AND AN ELECTRONIC DATA TRANSMISSION SYSTEM - The invention relates to a method of authentication and session key agreement for secure data transmission between a first and second data communication entity in an electronic data transmission system. Furthermore, the invention relates to an electronic transmission system to perform a method of authentication and session key agreement. | 04-05-2012 |
Hai-Kun Liu, Heidelberg DE
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20110038873 | MEANS AND METHODS FOR TREATING OR PREVENTING BRAIN TUMORS BASED ON THE NUCLEAR RECEPTOR TAILLESS (TLX) - The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs. | 02-17-2011 |
20130189267 | MEANS AND METHODS FOR TREATING OR PREVENTING BRAIN TUMORS BASED ON THE NUCLEAR RECEPTOR TAILLESS (TIX) - The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs. | 07-25-2013 |
Liu Liu, Nuremberg DE
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20140266100 | Method to Limit the Inrush Current in Large Output Capacitance LDO's - The present document relates to a pre-charge circuit of electronic circuits having Miller compensation and significant output capacitance such as LDOs or multistage amplifiers. The pre-charge circuit limits an inrush current right after enabling of the electronic circuit. The pre-charge circuit limits and clamps the fast charging of the Miller capacitor. A delay circuit disables the pre-charge circuit when the bias conditions of the Miller capacitor are close to normal bias conditions. | 09-18-2014 |
Liu Liu, Germering DE
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20120280667 | Flexible load current dependent feedback compensation for linear regulators utilizing ultra-low bypass capacitances - The present document relates to low-dropout (LDO) regulators having low output capacitance. The regulator comprises a differential amplification stage configured to amplify a differential voltage between a reference voltage and a measure of the output voltage, thereby yielding a drive current at an output of the amplification stage; a subsequent output amplification stage configured to provide the regulated output voltage and a output current at an output of the output amplification stage, based on a drive voltage at an input of the output amplification stage; and a first output current feedback loop configured to sense the output current; and feed back a first coupling current derived from the sensed output current to a first intermediate point between the output of the differential amplification stage and the input of the output amplification stage; wherein the drive voltage is dependent on the drive current and the first coupling current. | 11-08-2012 |
20130147447 | High-Speed LDO Driver Circuit using Adaptive Impedance Control - The present document relates to linear regulators or linear voltage regulators configured to provide a constant output voltage. In particular, the present document relates to driver circuits of low-dropout (LDO) regulators. A driver circuit ( | 06-13-2013 |
Miaoyin Liu, Mainz DE
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20110168264 | POLY(5,5'-BIS(THIOPHEN-2-YL)-BENZO[2,1-B;3,4-B']DITHIOPHENE) AND ITS USE AS HIGH PERFORMANCE SOLUTION PROCESSABLE SEMICONDUCTING POLYMER - Poly(5,5′-bis(thiophen-2-yl)-benzo[2,1-b;3,4-b′]dithiophene) comprising as repeating units the group of the formula (I) wherein R is independently selected from a) a C | 07-14-2011 |
Ningshu Liu, Berlin DE
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20110251191 | USE OF SUBSTITUTED 2, 3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES FOR THE TREATMENT OF MYELOMA - The present invention relates to the use of 2,3-dihydroimidazo[1,2-c]quinazoline compounds, and of pharmaceutical compositions containing such compounds, for the treatment or prophylaxis of multiple myeloma, as a sole agent or in combination with other one or more other active ingredients. | 10-13-2011 |
20120129833 | CYCLIC KETOENOLS FOR THERAPY - The invention relates to 5′-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of diabetes, obesity, hyperlipidaemia, fatty livers and of disorders of the cardiovascular system. | 05-24-2012 |
20130040935 | CYCLIC KETO-ENOLS FOR THERAPY - The invention relates to 5′-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumour disorders. | 02-14-2013 |
20130184270 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE-CONTAINING COMBINATIONS - The present invention relates to: combinations of: component A: one or more 2,3-dihydroimidazo[1,2-c]quinazoline compounds of general formula (A1) or (A2), or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof; component B: one or more N-(2-arylamino)aryl sulfonamide compounds of general formula (B), or Lapatinib, or Paclitaxel, or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof; and, optionally, component C: one or more further pharmaceutical agents; in which optionally some or all of the components are in the form of a pharmaceutical formulation which is ready for use to be administered simultaneously, concurrently, separately or sequentially. dependently of one another by the oral, intravenous, topical, local installations, intraperitoneal or nasal route; use of such combinations for the preparation of a medicament for the treatment or prophylaxis of a cancer; and a kit comprising such a combination. | 07-18-2013 |
20130310362 | FUSED PYRIMIDINES - The present invention relates to compounds of formula (I), | 11-21-2013 |
20130317002 | FUSED PYRIMIDINES - Compounds of formula (I) | 11-28-2013 |
20130317004 | AMINOALCOHOL SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS - This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 11-28-2013 |
20130330327 | ALKOXY-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES - The present invention relates to alkoxy-substituted 2,3-dihydroimidazo[1,2-c]quinazoline compounds of general formula (I) in which R1, R2 and R3 are as defined in the claims, to methods of preparing said compounds, to intermediates for the preparation of said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 12-12-2013 |
20140011853 | SUBSTITUTED 3-(BIPHENYL-3-YL)-8,8-DIFLUORO-4-HYDROXY-1-AZASPIRO[4.5]DEC-3-EN-2-ONES FOR THERAPY - The invention relates to substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones of the formula (Ia) for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumour disorders. | 01-09-2014 |
20140031407 | (5S,8S)-3-(4'-CHLOR-3'-FLUOR-4-METHLYBIPHENYL-3-YL)-4-HYDROXY-8-METHOXY-1-- AZASPIRO[4.5]DEC-3-EN-2-ONE (COMPOUND A) FOR TREATMENT - The invention relates to (5s,8s)-3-(4′-chloro-3′-fluoro-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumour disorders. | 01-30-2014 |
20140113896 | ARYLAMINOALCOHOL-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINOLINES - The present invention relates to substituted phenoxypyridine compounds of general formula (I); in which R | 04-24-2014 |
20140243295 | USE OF SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES - The present invention relates to: —use of a 2,3-dihydroimidazo[1,2-c]quinazoline compound, or of a pharmaceutical composition containing same, as a sole active agent, or of a combination of a) said compound or a pharmaceutical composition containing said compound and b) one or more further active agents, for the preparation of a medicament for the treatment or prophylaxis of cancer; —combinations of a) said compound and b) one or more further active agents; —a pharmaceutical composition comprising said compound as a sole active agent for the treatment of breast cancer; —a pharmaceutical composition comprising a combination of a) said compound and b) one or more further active agents; —use of biomarkers involved in the modification of Bel expression, HER family expression and/or activation, PIK3CA signaling and/or loss of PTEN for predicting the sensitivity and/or resistance of a cancer patient to said compound and providing a rationale-based synergistic combination as defined herein to increase sensitivity and/or to overcome resistance; and —a method of determining the level of a component of one or more of Bcl expression, HER family expression and/or activation, PIK3CA signaling and/or loss of PTEN. | 08-28-2014 |
20140275199 | SUBSTITUTED 3-(BIPHENYL-3-YL)-4-HYDROXY-8-METHOXY-1-AZASPIRO[4.5]DEC-3-EN-2-ONE - The invention relates to substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-ones, in particular for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of neoplastic disorders. | 09-18-2014 |
20150080374 | AMINOALCOHOL SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS - This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 03-19-2015 |
Pingli Liu, Newark DE
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20100190981 | PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS - The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases. | 07-29-2010 |
Steven Liu, Kaiserslautern DE
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20120314466 | CONTROL OF A MODULAR CONVERTER HAVING DISTRIBUTED ENERGY STORES WITH THE AID OF AN OBSERVER FOR THE CURRENTS AND AN ESTIMATING UNIT FOR THE INTERMEDIATE CIRCUIT ENERGY - Methods and configurations controlling a converter having controllable power semiconductors, compare actual and target state values to obtain control difference values for a control unit producing setting voltage values. Control electronics provide control signals according to setting voltage values and transmit them to power semiconductors. The control unit generates voltage values so control difference values become small. Current and converter energy controls and energy balancing are performed jointly, actual state values are calculated by an observing unit based on setting voltage values considering measured current values and actual state intermediate-circuit energy values are calculated by an estimating unit considering measured intermediate-circuit energy values of positive and negative voltage sources. The observing and estimating units model the converter so actual state current and intermediate-circuit steady-state energy values correspond to error-free current and intermediate-circuit energy values. A periodic time-variant gain controller receives error-free values. | 12-13-2012 |
Vincent Liu, Bochum DE
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20100098601 | System for extracting hydrogen from a gas containing methane - A system for extracting hydrogen from a gas containing methane, especially natural gas. Hydrocarbons contained in the gas are catalytically broken down in a reformer by steam in order to form hydrogen, carbon monoxide and carbon dioxide. Catalytic conversion of the obtained carbon monoxide with steam occurs in a downstream conversion step in order to form carbon monoxide and water. Carbon dioxide is removed from the converted gas flow by gas washing, and the washed hydrogen-rich gas flow is subsequently divided in a pressure-swing adsorption system into a product gas flow made of hydrogen and a waste gas flow. The waste gas flow is introduced with hydrogen, which is separated from the gas flow after gas washing, into a reformer which is essentially a carbon-free combustible gas, and is combusted there. | 04-22-2010 |
20110061529 | PROCESS AND DEVICE FOR THE SEPARATION OF FOREIGN GASES FROM A REDUCING USEFUL GAS BY STEAM-DRIVEN PRESSURE SWING ADSORPTION - A process is described for purifying synthesis gas by means of a pressure swing adsorption unit which is desorbed by a vacuum produced by a so-called ejector, which is driven by steam generated by a heat exchanger which uses the heat in the flue gas duct or in the useful-gas duct for the generation of steam. The pressure swing adsorption unit is operated advantageously in cyclic turns of adsorption under excess pressure, depressurization desorption and vacuum desorption and the gas desorbed by the ejector being cooled in a cooler so that the contained steam can be condensed and discharged or is advantageously returned to the feed gas for the synthesis gas production. The foreign gas desorbed by the pressure swing adsorption unit, which contains at least partly not yet consumed fuel gas, is recycled to the fuel gas. In an advantageous embodiment, the vacuum from the ejector is stored in an intermediate tank and applied to the pressure swing adsorption unit according to the vacuum desorption cycle. Also disclosed is a device for running this process. | 03-17-2011 |
Xiong Liu, Stuttgart DE
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20130087716 | CHARGED PARTICLE SOURCE - A charged particle source comprises at least one gas inlet configured to supply gas particles, at least one tip having a tip apex being biased to provide an electrical field for generating charged particles, and at least one ionization area to which gas particles are supplied. The gas particles are ionized in the ionization area due to the electrical field. Additionally, the charged particle source comprises at least one first electrode configured to accelerate charged particles and at least one light emitting device providing a light beam. The light beam is focused to a focus point in the ionization area, specifically, to a focus volume such that the ionization area is at least partly positioned in the focus volume. The ionization area is arranged between the tip apex and the first electrode. The distance between the ionization area and the tip apex may be from 0.1 nm to 1 nm. | 04-11-2013 |
Xiufei Liu, Muenchen DE
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20080307639 | Vehicle for Laying at Least One Electric Line Into the Grooves of a Longitudinal Stator - The invention relates to a laying vehicle for laying electric lines ( | 12-18-2008 |
Xiufei Liu, Poing DE
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20080307997 | Flexible Steel Girder and Switch Assembly Producer Therewith for Magnetic Levitation Railways - The invention relates to a bending mount ( | 12-18-2008 |
20090013898 | SWITCH ASSEMBLY FOR MAGNETIC LEVITATION RAILWAYS - Disclosed is a switch arrangement for magnetically levitated railways, comprising a support ( | 01-15-2009 |
20140318408 | Drive Apparatus for a Magnetic Levitation Transport System - The present invention relates to a drive apparatus for a magnetic levitation transport system comprising a short-stator linear motor, wherein a primary part of the linear motor is provided with a winding ( | 10-30-2014 |
Yan-Hong Liu, Frankfurt DE
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20090111838 | 6-ARYLAMINO-5-CYANO-4-PYRIMIDINONES AS PDE9A INHIBITORS - The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) | 04-30-2009 |
Yaqian Liu, Ludwigshafen DE
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20090131281 | Drilling Fluid containing hydrophobin - The present invention relates to the use of at least one hydrophobin or at least one hydrophobin derivative in a drilling mud. | 05-21-2009 |
20100130385 | PRODUCTION AND USE OF PARAFFIN INHIBITOR FORMULATIONS - A process for preparing a paraffin inhibitor formulation comprising (a) preparing a mixture comprising a waxy paraffin inhibitor component having a melting point of >0° C. and an emulsifier component, wherein the mixture is prepared at a first temperature range above the melting point of the waxy paraffin inhibitor; (b) adding water to the mixture to produce an o/w emulsion; and (c) cooling the o/w emulsion to a temperature in a second temperature range which is below the melting point of the waxy paraffin inhibitor. The mixture prepared in step (a) may further comprise water to produce a w/o emulsion, the water being present in a proportion by weight that is lower than the sum of the proportions by weight of the paraffin inhibitor and the emulsifier component. The process may further comprise (d) adding an at least partially water-miscible organic solvent in which the paraffin inhibitor is insoluble. | 05-27-2010 |
20110045671 | COMPOSITION FOR POLISHING SURFACES OF SILICON DIOXIDE - A composition for polishing surfaces comprises the following components: | 02-24-2011 |
Yingjia Liu, Munich DE
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20140105298 | INTER-FRAME PREDICTION CODING METHOD, DEVICE AND SYSTEM - Inter-frame prediction coding method, device and system are provided. The inter-frame prediction coding method includes: calculating distortions between a template area of current encoding block and each of M matching templates in L reference frames, to determine M offset vectors; acquiring M hypothesis prediction values of the encoding block to which the M matching templates correspond according to the determined M offset vectors, and calculating the template matching prediction value of the current encoding block according to the M hypothesis prediction values; comparing the template matching prediction value and original value of the current encoding block to acquire the residual of the current encoding block, and encoding the residual. The technical solution improves prediction performance of the video coding system and increases coding efficiency. | 04-17-2014 |
Yingzhi Liu, Rotenberg DE
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20130091342 | TRACING SOFTWARE EXECUTION OF A BUSINESS PROCESS - Various embodiments of systems and methods to trace an execution of a business process are disclosed. Business rules and corresponding business objects required to execute the business process are identified and rendered to receive an input. Based upon detecting a trigger to execute the business process, the business rules and the corresponding business objects are processed to compute a process-resultant for the business process. A process-path of the computed process-resultant is traced by tracing key-strings corresponding to the business objects involved in computing the process-resultant, to generate a trace-resultant. The trace-resultant is parsed by determining versioned business objects and business information of the key-strings, to derive a business definition for the traced business objects involved in computing the process-resultant. Based upon the business definition, a comprehensive trace-map comprising a compilation of the process-resultant to execute the business process is generated. | 04-11-2013 |
Yubo Liu, Muelheim DE
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20120090392 | SEALING DEVICE FOR A DEVICE FOR MEASURING THE FILL LEVEL IN A FLUID CONTAINER - A sealing device for a device for measuring a fill level in a fluid container, particularly in a pressure container of a nuclear facility, includes at least one thermocouple which is connected by a pressure pipe to the pressure container and a pipeline connected to the pressure pipe to an evaluation unit. The pressure pipe and the pipeline are connected to each other by a pipe screw connection including a central part having two threaded pieces. One threaded piece is connected by a screw connection to a pipe sleeve and the other threaded piece is connected by a further screw connection to the pressure pipe. | 04-19-2012 |
Yuefei Liu, Neu-Ulm DE
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20100280123 | FOOD SUPPLEMENT CONTAINING ALPHA-KETO ACIDS FOR SUPPORTING DIABETES THERAPY - Food supplement containing alpha-keto acids for supporting diabetes therapy. The present invention relates to a formulation which is used as food supplement and contains alpha-keto acids for supporting therapy in diabetes mellitus type II (DM). | 11-04-2010 |
Zhenyu Liu, Freiburg DE
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20100268514 | Design of MRI gradient coil - A method for designing an electromagnetic gradient coil for magnetic resonance imaging systems. The method includes the steps of: choosing a set of objectives L | 10-21-2010 |