Neil P.
Neil P. Jones, Twyford GB
Patent application number | Description | Published |
---|---|---|
20090239932 | Antisense oligonucleotides against protein kinase isoforms alpha, beta and gamma - Antisense compounds are provided for inhibiting PKB (protein kinase B) alpha, beta and gamma. The antisense compounds display high potency and selectivity. The antisense compounds do not suffer from problems of dimerisation or self-hybridization and have also been selected to not affect other enzymes. The antisense compounds may be used singularly or in combination to inhibit one, two or all of PKB alpha, beta and gamma and hence treat conditions in which these enzymes are important. | 09-24-2009 |
Neil P. Mclarnon, Draperstown GB
Patent application number | Description | Published |
---|---|---|
20150199982 | Varying Write Pole Side Shield Gap - A magnetic element can be constructed by forming a write pole with a tip portion that continuously extends from an air bearing surface (ABS) along a plane orthogonal to the ABS to a body portion that continuously extends from the tip portion distal the ABS. A first write gap layer can then be deposited in contact with the write pole before a processing layer is deposited in contact with the first write gap layer. A magnetic shield may then be formed atop the processing layer with the magnetic shield being separated from the write pole by a first gap distance on the ABS throughout the tip portion and by a second gap distance distal the ABS along the plane orthogonal to the ABS along the body portion. The first and second gap distances can be measured parallel to the ABS with the second gap distance being greater than the first gap distance. | 07-16-2015 |
20150199983 | Varying Write Pole Side Shield Gap - A magnetic element can be configured with a write pole that continuously extends from an air bearing surface along a plane orthogonal to the air bearing surface. A magnetic shield can be separated from the write pole by a first gap distance on the air bearing surface throughout a tip portion of the write pole and by a second gap distance distal the air bearing surface along the plane orthogonal to the air bearing surface along a body portion of the write pole with the first and second gap distances measured parallel to the air bearing surface and the second gap distance being greater than the first gap distance. | 07-16-2015 |
Neil P. Ranaweera, Kelston NZ
Patent application number | Description | Published |
---|---|---|
20130125451 | METHOD FOR REPELLING AND/OR CONTROLLING PESTS - A method and composition for repelling and/or controlling at least one pest. The method comprising contacting at least one subject, article and/or locus with a composition comprising (i) 2-undedanone, 2-tridecanone or a mixture thereof; and (ii) neem plant, part and/or extract thereof. | 05-23-2013 |
Neil P. Shah, Mill Valley, CA US
Patent application number | Description | Published |
---|---|---|
20090197893 | Methods of Identifying and Treating Individuals Exhibiting Complex Karyotypes - The invention described herein relates to diagnostic and therapeutic methods and compositions useful in the management of disorders, for example cancers, involving cells that harbor complex karyotypes. The present invention also related to mutant BCR-ABL kinase proteins, and to diagnostic and therapeutic methods and compositions useful in the management of disorders, for example cancers, involving cells that express such mutant BCR-ABL kinase proteins. | 08-06-2009 |
Neil P. Soice, Merrimack, NH US
Patent application number | Description | Published |
---|---|---|
20100065498 | Novel Coated Membranes and Other Articles - The present invention provides porous media or membranes having a surface coating that includes a cross-linked terpolymer which has a superior combination of properties, including heat stable biomolecule resistant adsorptive properties, resistance to strong alkaline solutions, and low levels of extractable matter. In some preferred embodiments, the porous media is a porous membrane. | 03-18-2010 |
20120024787 | Novel Coated Membranes and Other Articles - The present invention provides porous media or membranes having a surface coating that includes a cross-linked terpolymer which has a superior combination of properties, including heat stable biomolecule resistant adsorptive properties, resistance to strong alkaline solutions, and low levels of extractable matter. In some preferred embodiments, the porous media is a porous membrane. | 02-02-2012 |
20120288630 | Novel Coated Membranes and Other Articles - The present invention provides porous media or membranes having a surface coating that includes a cross-linked terpolymer which has a superior combination of properties, including heat stable biomolecule resistant adsorptive properties, resistance to strong alkaline solutions, and low levels of extractable matter. In some preferred embodiments, the porous media is a porous membrane. | 11-15-2012 |
Neil P. Soice, Amherst, NH US
Patent application number | Description | Published |
---|---|---|
20100196589 | Room temperature stable agarose solutions - Room temperature stable, non-gelling polysaccharide solutions such as agaroses, dextrans and cyclodextrans are made by the present invention. It has been found that by incorporating certain gel-inhibiting additives into an aqueous polysaccharide solution, the gel point is reduced or eliminated and the solution remains liquid at room temperature indefinitely. Additives that have been found to work include salts, such as lithium chloride and zinc chloride and bases, such as sodium hydroxide and lithium hydroxide. Mixtures of said salts and said bases can also be used with the same desired results. The composition of these solutions of the present idea can be further modified to include other additives, such as organic co-solvents or non-solvents, pH modifiers, surfactants or other polymers to customize the properties of the solution to improve the processability for the desired application and to form structures such as films, beads and coated porous substrates. | 08-05-2010 |
20100227015 | Method and apparatus for making porous agarose beads - The present invention relates to a method and apparatus for forming agarose or cored agarose beads. The process involves dissolving/gelation the agarose in a suitable liquid, mixing it with a hydrophobic liquid to form an emulsion and maintaining that emulsion at a temperature equal to or greater than the gelation point of the agarose, passing it through a static mixer to create agarose droplets and solidifying the agarose droplets in a second bath of hydrophobic liquid. The beads can then be washed and used or further processed to crosslink the agarose and/or add various functionalities on to the agarose. Another method for solidifying the agarose droplets is by using a heat exchanger to cool the stream continuously after it exits the static mixer. A similar process is used for the “cored” beads except cores, preferably in bead form, are introduced to the agarose before it enters the first hydrophobic liquid so that the agarose forms a coating on the cores. A similar process with either agarose beads (made by this or another process) or cored agarose (made by this or another process) can be used to add multiple layers of agarose on to the existing beads. An apparatus for running the process is also disclosed. | 09-09-2010 |
20110049042 | Porous adsorptive or chromatographic media - A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substrate has good convective and diffusive flow and capacity. The substrate may be cross-linked, have one or more capture chemistries attached to it and is useful as a chromatography media for the selective filtration of desired species including biomolecules such as proteins and DNA fragments. | 03-03-2011 |
20110311762 | ROOM TEMPERATURE STABLE AGAROSE SOLUTIONS - The present invention provides porous functionalized crosslinked polysaccharide hydrogel coated structures and methods for making the same. The methods include impregnating a porous substrate with a room temperature stable aqueous polysaccharide solution containing, water, a polysaccharide having a concentration in the aqueous solution from about 0.1% to about 20%, a gel-inhibiting agent having a concentration in the aqueous solution from about 18 to about 54%, and an anionic fluorosurfactant having a concentration in the aqueous solution from about 0.001% to about 10% by total weight of the aqueous solution. Followed by evaporating the water from the polysaccharide coating; and exposing the dehydrated polysaccharide coating to a gelling agent form a porous polysaccharide hydrogel coated substrate. The hydrogel coated substrate is exposed to a crosslinking agent to form a porous crosslinked polysaccharide hydrogel coated substrate, which is then functionalized by the attachment of a ligand. | 12-22-2011 |
20150060342 | Porous Adsorptive Or Chromatographic Media - A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substrate has good convective and diffusive flow and capacity. The substrate may be cross-linked, have one or more capture chemistries attached to it and is useful as a chromatography media for the selective filtration of desired species including biomolecules such as proteins and DNA fragments. | 03-05-2015 |
Neil P. Young, Woodside, CA US
Patent application number | Description | Published |
---|---|---|
20100062675 | SYSTEM AND METHOD FOR SUBSTANTIALLY SYNCHRONIZING SOUND AND SMOKE IN A MODEL VEHICLE - A system and method is provided for substantially synchronizing sound and smoke, or the like, in a model train or other model vehicle. In one embodiment of the present invention, a sensor is configured to send a signal periodically to a smoke generating device and a controller, wherein the signal is used by the smoke generating device to produce a particular quantity of smoke. The controller is then configured to receive a signal from a motor, wherein the signal includes information (e.g., a count) that can be used to identify a rotational position of the motor, or a rotational position of an axle in communication with the motor. The controller then uses the signal from the sensor and the signal from the motor to estimate (or predict) a transmission time of a next (or second) signal from the sensor, wherein the next (or second) signal is used by the smoke generating device to produce a next (or second) production of smoke. In one embodiment of the present invention, the controller does this by (i) using the signal from the sensor to identify a first count from the motor, and (ii) using the first count from the motor (e.g., together with “chuffs” per revolution) to identify a second count from the motor, wherein the second count corresponds to a transmission time of a next (or second) signal from the sensor. The controller then uses the “estimated time” to transmit a signal to the sound generating device, wherein the signal is used by the sound generating device to produce a “chuffing” sound that is substantially synchronized to a next (or second) production of smoke. | 03-11-2010 |
Neil P. Young, Redwood City, CA US
Patent application number | Description | Published |
---|---|---|
20100094483 | CONTROL AND MOTOR ARRANGEMENT FOR USE IN MODEL TRAIN - A control and motor arrangement in accordance with the present invention includes a motor configured to generate a locomotive force for propelling the model train. The control and motor arragement further includes a command control interface configured to receive commands from a command control unit wherein the commands correspond to a desired speed. The control and motor arrangement still further includes a plurality of detectors configured to detect speed information of the motor, and a process control arrangement configured to receive the speed information from the sensors. The process control arrangement is further configured and arranged to generate a plurality of motor control signals based on the speed information for controlling the speed of said motor. The control and motor arrangement yet still further includes a motor control arrangement configured to cause power to be applied to the motor at different times in response to the motor control signals. | 04-15-2010 |