Patent application number | Description | Published |
20090195369 | Method and system for tracking a vehicle - A system for tracking a fleeing vehicle, using optional remote sensing to identify a payload contained in the vehicle or asset, and an optional device disabling the fleeing vehicle via disrupting the vehicle's onboard computer or electrical system. The system includes a tracking device or carrier containing tracking components, sensing equipment, and the vehicle disabling device. A launcher of the tracking device may be handheld or vehicle mounted, and may use high pressure gas or another propellant to launch the projectile at a fleeing vehicle. The electronics package may include tracking hardware, sensing hardware, and the vehicle disabling hardware. Once launched and affixed to the suspect vehicle or stationary target, the vehicle's location can be tracked while sensors detecting any trace elements of explosives, IED (Improvised Explosive Device) materials, WMD (Weapons of Mass Destruction), biochemical materials, drugs, or any form of contraband can be monitored from a safe distance. In the case of a vehicle or moving target, the vehicle may then be disabled from a safe distance if sensors detect any abnormality in the targeted vehicle's payload. | 08-06-2009 |
20120166021 | METHOD AND SYSTEM FOR TRACKING AND/OR DISABLING A VEHICLE - A system for disabling a fleeing vehicle via disrupting the vehicle's onboard computer or electrical system. The system optionally includes a tracking system for tracking the vehicle's location and/or a remote sensing system for identifying a payload contained in the vehicle or asset. A launcher of the disabling/tracking device may be handheld or vehicle mounted, and may use high pressure gas or another propellant to launch the projectile at a fleeing vehicle. The system may include a tether for connecting the disabling device to a power supply disposed on a pursuit vehicle or a handheld launcher. | 06-28-2012 |
Patent application number | Description | Published |
20080287665 | CANINE IgG NUCLEIC ACID MOLECULES - The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha chain (IL-13Rα) proteins, particularly canine interleuken receptor alpha 1 (IL-13Rα1) and canine interleuken receptor alpha 2 (IL-13Rα2) proteins. Also included are canine IgG and IL-13Rα proteins, antibodies having selectivity for such proteins, inhibitors of such proteins and/or nucleic acid molecules, cells transformed with said nucleic acid molecules, assays employing such cells, nucleic acids molecules, proteins, antibodies and/or inhibitors, and therapeutic compositions comprising said nucleic acids molecules, proteins, antibodies and/or inhibitors. Also included are kits containing said molecules or chimera thereof, including their use to evaluate and regulate an immune response in an animal. | 11-20-2008 |
20090111970 | CANINE AND FELINE IMMUNOREGULATORY PROTEINS, NUCLEIC ACID MOLECULES, AND USES THEREOF - The present invention relates to canine interleukin-5 proteins; canine interleukin-5 nucleic acid molecules, including those that encode canine interleukin-5 proteins; to antibodies raised against such proteins; and to inhibitory compounds that regulate such proteins. The present invention also includes methods to identify and obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to regulate an immune response in an animal. | 04-30-2009 |
Patent application number | Description | Published |
20100090440 | SYSTEM AND METHOD FOR PROVIDING GYROSCOPIC STABILIZATION TO A WHEELED VEHICLE - This invention provides a stabilizing system and method for two-wheeled vehicles that affords the rider no restriction on the full range of movements (banks, leans, etc.) common to bicycles, but that provides greater stability during turns and other maneuvers so that an unintentional bank or tilt (potentially causing a fall) is less likely, even at relatively slow speeds and startup. A rotating mass of predetermined mass-value and radial mass-distribution is provided coaxially with the front axle. The mass is supported on bearings so as to freewheel with respect to the rotation of the front wheel. As such it can be induced to spin significantly faster than the front wheel thereby generating a gyroscopic effect at the front wheel about the axle. This gyroscopic effect influences the steering of the wheel by the rider. Due to precession, the wheel tends to follow any excessive bank by the vehicle, ensuring that the rider can “steer-out-of” an unintended tilt or bank. Likewise, the gyroscopic effect limits the rider's ability to execute excessive steering, thereby preventing jackknife movements. The mass can be an electric-motor-driven flywheel within a shell housing that includes a battery, control system and drive motor. The drive motor engages a surface of the flywheel with a drive tire in a resilient manner to reduce potential damage to the motor. | 04-15-2010 |
20120319456 | SYSTEM AND METHOD FOR PROVIDING GYROSCOPIC STABILIZATION TO A WHEELED VEHICLE - This invention provides a stabilizing system and method for two-wheeled vehicles that affords the rider no restriction on the full range of movements (banks, leans, etc.), while providing greater stability during turns and other maneuvers so that an unintentional bank or tilt (potentially causing a fall) is less likely, even at slow speeds and startup. A rotating mass of predetermined mass-value and radial mass-distribution is provided coaxially with the front axle. The mass is supported on bearings and freewheels with respect to the rotation of the front wheel. It can be induced to spin significantly faster than the front wheel thereby generating a gyroscopic effect at the front wheel about the axle. The gyroscopic effect limits the rider's ability to execute excessive steering, thereby preventing jackknife movements. The mass can be an electric-motor-driven flywheel within a shell housing that includes a drive tire battery, control system and drive motor. | 12-20-2012 |
Patent application number | Description | Published |
20090197227 | RELATIONSHIP PERFORMANCE SYSTEM AND METHOD - An apparatus for negotiating a work role relationship between two participants, comprising a Dialog and Agreement Board with multiple in-dialog areas where participants place one or more cards representing elements or parts of the work role relationship or personal characteristics related to the work role, and with a commitment area upon which cards can be taken from the in-dialog areas and placed to represent agreed-upon commitments by the participants. An agreement between the participants may be documented manually or automatically, in whole or in part. Components marked with bar codes can be read for entry into a computer program for documenting agreements. | 08-06-2009 |
20120096074 | RELATIONSHIP QUALITY EVALUATION AND REPORTING - A system for relationship information evaluation and management. The system incorporates relationship quality parameters that define the contextual parameters of quality, which are mutually validated and are accepted by the respective parties within an existing or prospective relationship. A computer, computing device, written documents or other means are used to capture the perspectives of each person, representative, or entity within the relationship or prospective relationship. This can be done automatically, on a random, periodic, or scheduled basis, or upon manual initiation. The information or data may then be analyzed and coalesced into a meaningful whole (or segments thereof), which may then be archived, printed, reported, and presented to one or both of the parties, or others. The information can be processed and stored based upon certain parameters, attributes, types or classes or relationships, so as to provide history, patterns, trends, alerts, warnings, analyses or comparisons concerning relationship quality. All information collected can be further applied or aggregated within an organization (or beyond, such as in a general locality or marketplace). | 04-19-2012 |
20150026589 | RELATIONSHIP QUALITY EVALUATION AND REPORTING - A system for relationship information evaluation and management. The system incorporates relationship quality parameters that define the contextual parameters of quality, which are mutually validated and are accepted by the respective parties within an existing or prospective relationship. A computer, computing device, written documents or other means are used to capture the perspectives of each person, representative, or entity within the relationship or prospective relationship. This can be done automatically, on a random, periodic, or scheduled basis, or upon manual initiation. The information or data may then be analyzed and coalesced into a meaningful whole (or segments thereof), which may then be archived, printed, reported, and presented to one or both of the parties, or others. The information can be processed and stored based upon certain parameters, attributes, types or classes or relationships, so as to provide history, patterns, trends, alerts, warnings, analyses or comparisons concerning relationship quality. All information collected can be further applied or aggregated within an organization (or beyond, such as in a general locality or marketplace). | 01-22-2015 |
Patent application number | Description | Published |
20110239346 | Microclimate System for Protective Body Armor - A constant or controlled temperature microclimate protective system capable of providing either cooling or heating. Such a system may be used alone or in combination with protective armor without degrading the force impact integrity of the protective system. When used alone, the microclimate system of the present invention may be constructed into a garment configuration for personal use or a sleeve-type configuration for use with one or more electronic devices. When used in combination, the microclimate system may be integrally incorporated into a protective armor system, releasably attached or held within the protective armor system by means including but not limited to a pocket or pouch, or worn as a separate element underneath a protective armor system. The microclimate system may comprise a plurality of cells containing phase change material providing one or more transition temperature points while further assisting in impact shock attenuation. | 10-06-2011 |
20120079647 | Sports Protective Garment with Impact Force Protection and Microclimate Control - An impact absorbing protective garment is provided, for wearing about the torso of a body, such as a baseball umpire, that comprises three layers. There is an outer shell layer comprised of a plurality of plate elements that are generally stiff, shock-resistant lightweight material, that are fastened to a middle layer. The middle layer is in the form of a flexible pad having various components, and that provides an intermediate thickness of cushioning material inside the outer shell layer. There is an inner layer carried by the middle layer that comprises a plurality of cells of phase change material, with the various cells being separated from each other by sealing zones. Upon sufficient impact the individual cells can communicate through small pores in the sealing zones or when the sealing zones rupture under impact pressure, to assist in impact absorption. The inner layer, in its cells, contains a phase change material that is a means for effecting a relatively constant microclimate cooling or heating of the area of the torso of the body which it confronts. | 04-05-2012 |
Patent application number | Description | Published |
20110316580 | METHOD AND APPARATUS FOR DYNAMIC MEMORY TERMINATION - Described herein are a method and an apparatus for dynamically switching between one or more finite termination impedance value settings to a memory input-output (I/O) interface of a memory in response to a termination signal level. The method comprises: setting a first termination impedance value setting for a termination unit of an input-output (I/O) interface of a memory; assigning the first termination impedance value setting to the termination unit when the memory is not being accessed; and switching from the first termination impedance value setting to a second termination impedance value setting in response to a termination signal level. | 12-29-2011 |
20140181390 | METHOD, APPARATUS AND SYSTEM FOR EXCHANGING COMMUNICATIONS VIA A COMMAND/ADDRESS BUS - Techniques and mechanisms for exchanging information from a memory controller to a memory device via a command/address bus. In an embodiment, the memory device samples a first portion of a command during a first sample period and samples a second portion of the command during a second sample period, the first portion and second portion exchanged via the command/address bus. The first sample period and the second sample period are concurrent with, respectively, a first transition of a clock signal and a second transition of the clock signal. In another embodiment, a mode of the memory device determines a relationship between the first transition and the second transition. | 06-26-2014 |
20140184523 | LOW SWING VOLTAGE MODE DRIVER - An output driver includes control logic configured to switch on a pull-up circuit and a pull-down circuit to provide an output impedance for a logic low on a transmission line. The output driver includes a variable pull-up resistor. The control logic is configured to switch on the pull-up circuit to a first value of impedance to drive a logic high on the transmission line. The control logic is configured to switch on the pull-up circuit to a second value of impedance and to switch on the pull-down circuit to provide the output impedance to drive a logic low on the transmission line. The system could alternatively be configured for the inverse to switch on a combination of pull-up and pull-down circuits for a logic high, where the pull-down circuit is switched on for a logic low. | 07-03-2014 |
20140266320 | TRANSMITTER WITH VOLTAGE AND CURRENT MODE DRIVERS - Described is an integrated circuit (IC) which comprises: an input-output (I/O) pad for coupling to a transmission line; a voltage mode driver coupled to the I/O pad, the voltage mode driver having a pull-up driver and a pull-down driver; and a current mode driver coupled to the I/O pad, the current mode driver operable to function in parallel to the voltage mode driver. | 09-18-2014 |
20140372815 | APPARATUS AND METHOD TO REDUCE POWER DELIVERY NOISE FOR PARTIAL WRITES - Apparatus, systems, and methods to reduce power delivery noise for partial writes are described. In one embodiment, an apparatus comprises a processor and a memory control logic to insert one or more dummy unit intervals into data in a write operation when a number of state transitions between adjacent unit intervals exceeds a threshold. Other embodiments are also disclosed and claimed. | 12-18-2014 |
20150066819 | PERIODIC TRAINING FOR UNMATCHED SIGNAL RECEIVER - I/O parameters are adjusted based on a number of errors detected in a received training signal. A controller device sends the training signal while a memory device is in a training mode. The memory device samples the training signal and the system causes an adjustment to at least one I/O parameter based on a detected number of errors. Either the controller or the memory device can perform the error detection, depending on the configuration of the system. Either an I/O parameter of the controller or an I/O parameter of the memory device can be adjusted, depending on the configuration of the system. | 03-05-2015 |
Patent application number | Description | Published |
20090170184 | SYSTEM FOR FERMENTATION USING ALGAE - The system for fermentation using algae of the present invention includes a first reactor and a second reactor being in fluid communication with each other. A first valve placed between the first reactor and the second reactor controls the fluid connection between the reactors. A gas inlet, in fluid connection to the first reactor, is located at an end opposite the second reactor. A devolatization unit or cell lysis chamber is connected to the second reactor by a second valve. A biomass stream having gas, liquid and biosolids contents passes through the first reactor with gas. The biomass stream mixes and dissolves the gas in the reactors. The cellular structure of the biomass stream ruptures in the devolatization unit, allowing the processed materials, such as oil, gas, and biosolids, to be harvested for use. | 07-02-2009 |
20100068791 | SYSTEM AND METHOD FOR CONTINUOUS FERMENTATION OF ALGAE - The present invention is a method for fermentation of algae or algaefaction method. The method includes feeding a hydrocarbon composition into a gasifier and pre-heating a biomass stream from a fermentation reactor. The biomass stream includes a liquid portion, a catalyst, and a biomass solids portion ranging between 15-92% by weight ofthe biomass stream. The biomass solids portion is algae or algal solids. The biomass stream is pre-heated to a temperature range between 200° F. and 500° F. Both the syngas and the pre-heated biomass stream are injected as a mixture into a reactor, where the mixture is separated into a gas component, liquid component, and solids component. The solids component is algal crude, which can be collected for processing as transportation fuels. The gas component is a lower temperature syngas, which can also be collected for processing as electricity or transportation fuels. | 03-18-2010 |
20120064617 | SYSTEM AND METHOD FOR CONTINUOUS FERMENTATION OF ALGAE - The present invention is a method for fermentation of algae or algaefaction method. The method includes feeding a hydrocarbon composition into a gasifier and pre-heating a biomass stream from a fermentation reactor. The biomass stream includes a liquid portion, a catalyst, and a biomass solids portion ranging between 15-92% by weight of the biomass stream. The biomass solids portion is algae or algal solids. The biomass stream is pre-heated to a temperature range between 200° F. and 500° F. Both the syngas and the pre-heated biomass stream are injected as a mixture into a reactor, where the mixture is separated into a gas component, liquid component, and solids component. The solids component is algal crude, which can be collected for processing as transportation fuels. The gas component is a lower temperature syngas, which can also be collected for processing as electricity or transportation fuels. | 03-15-2012 |
Patent application number | Description | Published |
20080268302 | ENERGY PRODUCTION SYSTEMS AND METHODS - A photobioreactor includes a cultivation zone configured to contain a liquid culture medium and facilitate growth of a microalgae biomass, a plurality of parallel edge-lit light transmitting devices mounted within the cultivation zone, and a collection zone oriented in relation to the cultivation zone such that at least a portion of the liquid culture medium and microalgae from the cultivation zone may be periodically harvested. Methods for illuminating algae, for dissolving materials into an algae medium, for extracting oil from algae, and for producing biodiesel from algal oil are also provided. | 10-30-2008 |
20100028991 | Asymmetric compound parabolic concentrator and related systems - Various embodiments disclosed herein provide for an asymmetric compound parabolic concentrator (ACPC), a liquid light guide, and an algae mixer. These embodiments may be used singularly or in combination, for example, as part of a bioreactor. In various embodiments an ACPC may be used to capture light without the aid of motors or positioning. As such, the ACPC may be used despite seasonal solar variations. The illuminating light guide may be used to guide light, for example, from an exit aperture of an ACPC, through walls substantially perpendicular to the entrance window of the illuminating light guide. In some embodiments, the illuminating light guide may provide substantially uniform light distribution through a vertical profile. Other embodiments include, for example, an algae mixer and bioreactors. | 02-04-2010 |
20110094564 | Asymmetric Parabolic Compound Concentrator With Photovoltaic Cells - An asymmetric compound parabolic concentrator (ACPC) coupled with a photovoltaic cell is disclosed according to some embodiments. The disclosed ACPC can concentrate solar light from a large full acceptance angle toward the photovoltaic cell. In some embodiments, the ACPC can be submerged within a liquid (e.g., water). The liquid can increase the full acceptance angle, provide temperature damping, and provide structural inertia to the system. In some embodiments, the ACPC can be constructed from acrylic or other resins. | 04-28-2011 |
Patent application number | Description | Published |
20080220515 | APPARATUS AND METHODS FOR PRODUCTION OF BIODIESEL - A photobioreactor includes a cultivation zone configured to contain a liquid culture medium and facilitate growth of a microalgae biomass, a plurality of parallel edge-lit light transmitting devices mounted within the cultivation zone, and a collection zone oriented in relation to the cultivation zone such that at least a portion of the liquid culture medium and microalgae from the cultivation zone may be periodically harvested. Methods for illuminating algae, for dissolving materials into an algae medium, for extracting oil from algae, and for producing biodiesel from algal oil are also provided. | 09-11-2008 |
20110275140 | APPARATUS AND METHODS FOR PRODUCTION OF BIODIESEL - A photobioreactor includes a cultivation zone configured to contain a liquid culture medium and facilitate growth of a microalgae biomass, a plurality of parallel edge-lit light transmitting devices mounted within the cultivation zone, and a collection zone oriented in relation to the cultivation zone such that at least a portion of the liquid culture medium and microalgae from the cultivation zone may be periodically harvested. Methods for illuminating algae, for dissolving materials into an algae medium, for extracting oil from algae, and for producing biodiesel from algal oil are also provided. | 11-10-2011 |
20130133325 | POWER GENERATION DEVICE AND METHOD - A power generation device includes an enclosed circuit through which a working medium circulates. The working medium is heated at a first location in the enclosed circuit, and cooled at a second location. The differential heating and cooling causes the working medium to circulate within the enclosed circuit. The circulating medium is used to drive a turbine, which in turn may drive an electric generator. | 05-30-2013 |
Patent application number | Description | Published |
20080227985 | SYNTHESIS OF CHIRALLY PURIFIED SUBSTITUTED BENZOTHIAZOLES - Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein. | 09-18-2008 |
20090312323 | COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES - Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift. | 12-17-2009 |
20100087408 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 04-08-2010 |
20100267712 | ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES - Disclosed is a compound of Formula (I) in which W and R | 10-21-2010 |
20120083495 | COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES - Compounds useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift. | 04-05-2012 |
20120094970 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 04-19-2012 |
20120165318 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 06-28-2012 |
20120220589 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 08-30-2012 |
20120225846 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 09-06-2012 |
20120225863 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 09-06-2012 |
20120232056 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 09-13-2012 |
20120277224 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 11-01-2012 |
20130079316 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 03-28-2013 |
20130196962 | NON-HORMONAL STEROID MODULATORS OF NF-KB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 08-01-2013 |
20140100372 | SYNTHESIS OF CHIRALLY PURIFIED SUBSTITUTED BENZOTHIAZOLE DIAMINES - Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein. | 04-10-2014 |
20140128392 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds of Formula IIa: | 05-08-2014 |
20140142078 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 05-22-2014 |
20140235579 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 08-21-2014 |
20150031679 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK - Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus. | 01-29-2015 |
Patent application number | Description | Published |
20090308404 | FABRICS FOR PREVENTING AND REDUCING SKIN WOUNDS - A fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. The fabric includes a conductive yarn at about 0% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the fabric. The fabric can be used in bedding, including underpads, and patient gowns. Methods of preventing and treating skin wounds, and pressure wounds in particular, are also disclosed. | 12-17-2009 |
20090312684 | UNDERPAD FOR PREVENTING AND REDUCING SKIN WOUNDS - An underpad including a top fabric layer constructed of a therapeutic fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, is disclosed. The underpad also includes an absorbent middle layer and liquid impermeable bottom layer. The therapeutic fabric includes warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the therapeutic fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the therapeutic fabric of continuous filament polyester or nylon having non-round filament cross sections. The therapeutic fabric includes a conductive yarn at about 1% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the therapeutic fabric. A method of preventing and treating skin wounds, and pressure wounds in particular, is also disclosed. | 12-17-2009 |
20100050316 | SYNTHETIC WOVEN PATIENT GOWN FOR PREVENTING AND REDUCING SKIN WOUNDS - A patient gown comprised of therapeutic fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. The fabric includes a conductive yarn at about 1% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the fabric. A method of using the patient gown to prevent and treat skin wounds, and pressure wounds in particular, is also disclosed. | 03-04-2010 |
20110014836 | Fabrics for Therapeutic Skin Care Bedding - A fabric for bedding which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns being at least 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns being from about 0% to 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. An antimicrobial substance is topically applied or inherently available in the fabric. | 01-20-2011 |
Patent application number | Description | Published |
20080250141 | MONITORING SERVICE WITH INTER-ENTERPRISE CONTEXTUAL ANALYSIS - Methods and apparatuses for receiving data associated with one or more system metrics, contextually analyzing that data in view of prior received data of other computer systems of different subscriber enterprises, determining, based at least in part on the results of the contextual analysis, if an alert needs to be sent, and sending or causing to be sent an alert, are described herein. In various embodiments, the methods and apparatuses are further for managing computer systems of subscriber enterprises, including providing updated operating images. Other embodiments may also be disclosed. | 10-09-2008 |
20110071954 | PACKAGE SHIPPING SYSTEM AND METHOD, INCLUDING USAGE OF HISTORICAL ANALYTIC DATA - Embodiments provide methods, apparatus, systems, and computer-readable media associated with using historic analytic data to identify shipping options for a user to use when shipping a package. Historic analytic data may be received and maintained by a package shipment facilitation system. The analytics may then be used to generate business rules which may be applied to parameters for a package that is to be shipped. Through application of the business rules, one or more preferred shipping options may be identified. Business rules may be received after being manually-generated by a user, or may be automatically generated based at least in part on the maintained historic analytics. After a shipping option is chosen for the package, a shipping label may be printed for the package, and the package may be entered into a carrier's system for processing. | 03-24-2011 |
20120173450 | PACKAGE SHIPPING SYSTEM AND METHOD, INCLUDING USAGE OF HISTORICAL ANALYTIC DATA - Embodiments provide methods, apparatus, systems, and computer-readable media associated with using historic analytic data to identify shipping options for a user to use when shipping a package. Historic analytic data may be received and maintained by a package shipment facilitation system. The analytics may then be used to generate business rules which may be applied to parameters for a package that is to be shipped. Through application of the business rules, one or more preferred shipping options may be identified. Business rules may be received after being manually-generated by a user, or may be automatically generated based at least in part on the maintained historic analytics. After a shipping option is chosen for the package, a shipping label may be printed for the package, and the package may be entered into a carrier's system for processing. | 07-05-2012 |
20130138574 | PACKAGE AND FREIGHT SHIPPING SYSTEM AND METHOD, INCLUDING SHIPPING BY FULFILLMENT ENTITIES - In various embodiments, methods, apparatus, systems, and computer-readable media associated with using historic and real-time analytic data to select fulfillment entities and/or shipping options for a provider to use to fulfill an order from a customer. In various embodiments, an order may be received by a provider and order information may be made available to one or more fulfillment entities. The fulfillment entities may provide offers to fulfill the shipment to the provider, which may select one or more of the fulfillment entities based on application of business rules based at least in part on the historic and real-time analytic data. Other embodiments may be disclosed and claimed. | 05-30-2013 |
Patent application number | Description | Published |
20100004304 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MALIGNANT MELANOMA, BREAST, PROSTATE, COLON, PAPILLARY THYROID AND PANCREATIC CANCER - It is now recognized that chronic inflammation is an important risk factor for the development of cancer. The proinflammatory cytokine IL-6 is implicated in cancer because it is important for the activation of STAT, a key regulator of cancer growth, survival, metastasis, immune evasion and angiogenesis. Increased IL-6 and Stat-3 exists in vitro in pancreatic cancer, malignant melanoma, papillary thyroid cancer, breast cancer, colon cancer, and prostate cancer cells with high basal expression of Toll-like receptor 3 (TLR3) and Wnt5a. IL6/STAT3 activation, mediated by overexpressed TLR3 signaling, appears important in the tumor growth process, it may increase Wnt5a signaling, and be associated with increased cellular growth and migration. Using a novel inhibitor of pathologic TLR3 signaling (5-phenylmethimazole [C10]) we have demonstrated decreases in these markers plus suppression of cell growth and migration in human pancreatic cancer, malignant melanoma, papillary thyroid cancer, breast cancer, colon cancer, and prostate cancer cells. | 01-07-2010 |
Patent application number | Description | Published |
20120185472 | Relevancy Ranking of Search Results in a Network Based Upon a User's Computer-Related Activities - A computer-implemented method, system and computer program product providing ordered search results within a search engine. Items are retrieved from a network satisfying search criteria provided by a user. Computer-related activities performed by the user, including social networking activities, are determined, and the retrieved items are ranked based on the computer-related activities. The ranking of the retrieved items is dependent upon whether any retrieved item has been referenced by the social networking activities of the user, and the search results are provided including the retrieved items in order of the ranking. | 07-19-2012 |
20120284249 | Relevancy Ranking of Search Results in a Network Based Upon a User's Computer-Related Activities - A computer-implemented method, system and computer program product providing ordered search results within a search engine. Items are retrieved from a network satisfying search criteria provided by a user. Computer-related activities performed by the user, including social networking activities, are determined, and the retrieved items are ranked based on the computer-related activities. The ranking of the retrieved items is dependent upon whether any retrieved item has been referenced by the social networking activities of the user, and the search results are provided including the retrieved items in order of the ranking. | 11-08-2012 |
20130054705 | Tracking Desktop Application Referrals to Content Distributed Over a Network - Tracking initiation of network content requests is achieved by receiving at a network device requests from clients for network content, and tracking initiation of network content requests based upon initiator information, wherein the initiator information comprises information relating to each type of application hosted by a client that initiates the client request for network content from the network device. | 02-28-2013 |
20140123313 | ACCESSING INFORMATION DURING A TELECONFERENCING EVENT - A method for accessing information during a teleconferencing event. The method includes identifying a reference to a document transmitted by a telecommunication device participating in a teleconferencing event and identifying a name of the referenced document. The method includes determining, by a computer, an identity of a user of the participating telecommunication device. The method further includes determining the user has permission to access the identified document and, in response, transmitting the identified document to the participating telecommunication device. | 05-01-2014 |
20140123318 | ACCESSING INFORMATION DURING A TELECONFERENCING EVENT - A method for accessing information during a teleconferencing event. The method includes identifying a reference to a document transmitted by a telecommunication device participating in a teleconferencing event and identifying a name of the referenced document. The method includes determining, by a computer, an identity of a user of the participating telecommunication device. The method further includes determining the user has permission to access the identified document and, in response, transmitting the identified document to the participating telecommunication device. | 05-01-2014 |
20140189490 | DYNAMIC WEBPAGE CHANGE ANIMATION - A method, computer program product, and computer system for dynamic webpage change animation. A computer system detects one or more items that are changed on a second version of a webpage relative to a first version of the webpage. The computer system determines an animation order based on user environment. And, on the first version of the webpage and a template for generating the second version of the webpage, the computer system animates changes of the one or more items, according to the animation order. | 07-03-2014 |
Patent application number | Description | Published |
20080318460 | Electrical connection system - A connection position assurance retainer may include mechanisms for retaining connectors. For example, a female connector and a male connector may be mated and retained. Male and female terminals, the female terminal including a terminal insert, may also be provided. | 12-25-2008 |
20120003868 | ELECTRICAL CONNECTION SYSTEM THAT ABSORBS MULTI-CONNECTOR POSITIONAL MATING TOLERENCE VARIATION - A ganged electrical connection system includes an arrangement defining a plurality of receptacles. A plurality of first connectors is receivably coupled in the plurality of receptacles. A plurality of second connectors is matable to the plurality of coupled first connectors of the arrangement along mating axes. Positional mating tolerance variation associated with the plurality of second connectors in relation to the plurality of coupled first connectors manifested at the plurality of receptacles when the plurality of second connectors are mated to the plurality of coupled first connectors is absorbed by the arrangement. The plurality of the plurality of second connectors mate with the plurality of coupled first connectors in a single unimpeded, uninterrupted mating connection. A ganged electrical system for an electric-type vehicle is also presented. | 01-05-2012 |
20120142233 | DUAL CONTACT BEAM TERMINAL - A terminal is used in an electrical connector and receives a matable contact member. The terminal has a receptacle contact section has a bottom wall, an upper wall, and a primary and a secondary spring beam, or member. The primary member extends from a bottom wall and is bent back into the receptacle contact section. The primary member has an upper surface facing the upper wall and a lower surface opposite the upper surface. The primary member includes a free end that is spaced from the upper wall a distance less than a thickness of the matable contact member. The secondary member is formed from the bottom wall that extends into the contact section and includes a free end disposed beneath the lower surface of the primary member in an overlapping, spaced relationship thereto remote from the free end of the primary member. | 06-07-2012 |
20120302081 | ELECTRICAL CONNECTION SYSTEM HAVING DIELECTRIC SPRING TO ABSORB AXIAL POSITIONAL MATING TOLERANCE VARIATION FOR MULTIPLE CONNECTORS - A ganged electrical connection system includes an arrangement having a spring including a plurality of engagement portions. A plurality of first connectors is receivably coupled in a plurality of receptacles in the arrangement and a plurality of second connectors is matable to the coupled first connectors along mating axes. The plurality of coupled first connectors have floatable movement in the plurality of receptacles. The floatable movement is in at least an axial direction in relation to the plurality of receptacles and the axial positional mating tolerance variation of each second connector in the plurality of second connectors in relation to each first connector in the plurality of coupled first connectors that manifests at each receptacle in the plurality of receptacles is assimilated by each respective spring engagement portion when the plurality of second connectors mate to the plurality of coupled first connectors. | 11-29-2012 |
20120302084 | BI-DIRECTIONAL CPA MEMBER TO PREVENT UNMATING OF MULTIPLE CONNECTORS - A ganged electrical connection system includes a plurality of first connectors matable to a plurality of second connectors along mating axes, and a connector position assurance (CPA) member. The CPA member includes a plurality of tabs and a plurality of release fingers. The plurality of first connectors include a plurality of lock arms and the plurality of second connectors include a plurality of inclined ramps. The plurality of tabs receive the plurality of lock arms and the plurality of inclined ramps deflectingly engage said plurality of release fingers to allow movement of the CPA member in to a position of the CPA member, that when disposed in the position, keeps the plurality of second connectors from unmating from the plurality of coupled first connectors. Methods of fabricating an electrical connection system and a ganged electrical connection system that include the CPA member are also presented. | 11-29-2012 |
Patent application number | Description | Published |
20090236424 | IMAGE SENSOR BASED OPTICAL READER - An optical reader can include an image sensor. In one embodiment an optical reader can be configured to have different operating modes, the different operating modes optimizing the reader for reading different indicia. In another embodiment an optical reader can comprise a multiple color emitting light source. In another embodiment an optical reader can be provided in a specialized form factor including an enlarged head portion and an elongated body portion extending from the head portion. | 09-24-2009 |
20100084471 | DEVICE AND SYSTEM FOR PROCESSING IMAGE DATA REPRESENTING BAR CODES - A device for processing image data relating to bar codes is described. In one embodiment a bar code verification device is provided having an ergonomic form factor characterized by a domed hand held trigger and a viewing window. The verification device may be disposed in a network that includes a host processor system and other bar code reading devices which may include other bar code verification devices. Processing circuitry for processing image signals corresponding to printed bar codes may be partially disposed within the hand held verification device and partially disposed within a host processor system spaced apart from and associated with the hand held verification device. The hand held verification device may be in wireless communication with the host processor system to which it is associated. The bar code verification system may include signal enhancement modules which interpolate constructed pixel values from actual pixel values and which correct for signal degradation resulting from high frequency spatial sampling. | 04-08-2010 |
20100090006 | TERMINAL INCLUDING IMAGING ASSEMBLY - A terminal includes a housing, a touch screen, and an imaging assembly. The imaging assembly in one embodiment is disposed in the housing so that an imaging axis extends externally from the housing. The imaging assembly can be utilized for capture of images disposed externally to the housing. In one embodiment a frame of image data captured utilizing an imaging assembly can be processed for attempting to decode a decodable indicia. In one embodiment a frame of image data captured utilizing an imaging assembly can be stored. | 04-15-2010 |
20110121076 | IMAGE SENSOR BASED OPTICAL READER - An apparatus for use in optical reading can comprise an image sensor and a circuit board, and can further comprise a support assembly. An apparatus for use in optical reading can also comprise a light source and imaging optics. | 05-26-2011 |
20110297746 | DEVICE AND SYSTEM FOR PROCESSING IMAGE DATA REPRESENTING BAR CODES - A device for processing image data relating to bar codes is described. In one embodiment a bar code verification device is provided having an ergonomic form factor characterized by a domed hand held trigger and a viewing window. The verification device may be disposed in a network that includes a host processor system and other bar code reading devices which may include other bar code verification devices. Processing circuitry for processing image signals corresponding to printed bar codes may be partially disposed within the hand held verification device and partially disposed within a host processor system spaced apart from and associated with the hand held verification device. The hand held verification device may be in wireless communication with the host processor system to which it is associated. The bar code verification system may include signal enhancement modules which interpolate constructed pixel values from actual pixel values and which correct for signal degradation resulting from high frequency spatial sampling. | 12-08-2011 |
20120223140 | TERMINAL INCLUDING IMAGING ASSEMBLY - A terminal includes a housing, a touch screen, and an imaging assembly. The imaging assembly in one embodiment is disposed in the housing so that an imaging axis extends externally from the housing. The imaging assembly can be utilized for capture of images disposed externally to the housing. In one embodiment a frame of image data captured utilizing an imaging assembly can be processed for attempting to decode a decodable indicia. In one embodiment a frame of image data captured utilizing an imaging assembly can be stored. | 09-06-2012 |
20130208268 | DEVICE AND SYSTEM FOR PROCESSING IMAGE DATA REPRESENTING BAR CODES - A device for processing image data relating to bar codes is described. In one embodiment a bar code verification device is provided having an ergonomic form factor characterized by a domed hand held trigger and a viewing window. The verification device may be disposed in a network that includes a host processor system and other bar code reading devices which may include other bar code verification devices. Processing circuitry for processing image signals corresponding to printed bar codes may be partially disposed within the hand held verification device and partially disposed within a host processor system spaced apart from and associated with the hand held verification device. The hand held verification device may be in wireless communication with the host processor system to which it is associated. The bar code verification system may include signal enhancement modules which interpolate constructed pixel values from actual pixel values and which correct for signal degradation resulting from high frequency spatial sampling. | 08-15-2013 |
20130292477 | IMAGE SENSOR BASED OPTICAL READER - An apparatus for use in optical reading can comprise an image sensor and a circuit board, and can further comprise a support assembly. An apparatus for use in optical reading can also comprise a light source and imaging optics. | 11-07-2013 |
20140097249 | TERMINAL INCLUDING IMAGING ASSEMBLY - A terminal includes a housing, a touch screen, and an imaging assembly. The imaging assembly in one embodiment is disposed in the housing so that an imaging axis extends externally from the housing. The imaging assembly can be utilized for capture of images disposed externally to the housing. In one embodiment a frame of image data captured utilizing an imaging assembly can be processed for attempting to decode a decodable indicia. In one embodiment a frame of image data captured utilizing an imaging assembly can be stored. | 04-10-2014 |
Patent application number | Description | Published |
20120030653 | ASSUMPTION-BASED COMPILATION - Techniques for processing source code written in a traditionally interpreted language such as JavaScript, or another dynamic and/or interpreted language, are disclosed. In one example, compiled code associated with the source code is constructed and executed. An assumption on which a specific aspect of the compiled code is based (e.g., an optimization) is tested at a checkpoint of the compiled code. A roll over to fallback code is performed if the test indicates the assumption is not true. | 02-02-2012 |
20120030659 | CONSTRUCTING RUNTIME STATE FOR INLINED CODE - Techniques for processing computer code are disclosed. In one example, an indication that a computer code is to begin execution at a portion of code other than a starting portion of the code is received, and a runtime state associated with the portion of the code at which execution is to begin is constructed. In some examples, execution of the portion of code is initiated. In some examples, a program counter associated with the portion of the code is used to initiate execution of the code. In some examples, the computer code comprises a fallback code associated with a previously executing code. | 02-02-2012 |
20120030661 | OBSERVATION AND ANALYSIS BASED CODE OPTIMIZATION - Observation and analysis based optimization of software code is disclosed. An expected value is chosen for a dynamic attribute that cannot be determined, prior to execution of the associated software code, to be guaranteed to have that expected value at runtime. An optimized version of the software code is generated, including one or more optimizations based on an assumption that the dynamic attribute will have the expected value. Non-exhaustive examples of a dynamic attribute include a variable type; a location in memory; a location in which a global object, property, or variable is stored; the contents of a global function or method; and a value of a global property or variable. A check is performed during execution of the optimized version of the software code, prior to executing the portion that has been optimized based on the assumption, to verify that the dynamic attribute has the expected value. In the event that it is determined at runtime that the dynamic attribute does not have the expected value, execution reverts to backup code that is not based on the assumption that dynamic attribute will have the expected value. | 02-02-2012 |