Patent application number | Description | Published |
20100092477 | METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER - A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased. Specifically disclosed is an AR IgG1 Fc fusion protein, comprising the androgen binding domain of human androgen receptor and the Fc region of IgG. This fusion protein is used in the treatment of prostate cancer and testosterone flare. | 04-15-2010 |
20100291086 | USE OF ESTROGEN AND ANDROGEN BINDING PROTEINS IN METHODS AND COMPOSITIONS FOR TREATING GYNAECOLOGICAL CANCERS - The present invention provides a polypeptide comprising an estrogen or androgen binding region, the binding region capable of binding to an estrogen or androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available estrogen or androgen is decreased. The invention also provides for the treatment or prevention of cancers such as ovarian cancer, breast cancer and endometrial cancer using the polypeptides. | 11-18-2010 |
20110144032 | BIOLOGICAL APPLICATIONS OF STEROID BINDING DOMAINS - A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased. | 06-16-2011 |
20130064821 | METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER - A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased. Specifically disclosed is an AR IgG1 Fc fusion protein, comprising the androgen binding domain of human androgen receptor and the Fc region of IgG. This fusion protein is used in the treatment of prostate cancer and testosterone flare. | 03-14-2013 |
20140141104 | TREATMENT OF NEURODEGENERATIVE DISEASES - Use of selenate or a pharmaceutically acceptable salt thereof in methods and compositions for enhancing the activity of the protein phosphatase PP2A is provided. Methods of reducing phosphorylation of tau protein, inhibiting activity of GSK3 and treating or preventing neurodegenerative diseases are also described. | 05-22-2014 |
Patent application number | Description | Published |
20100016502 | COATING COMPOSITION - The invention provides a coating composition comprising a sol-gel matrix which comprises a binder and nanoparticles of a metal oxide, and nanoparticles and/or microparticles of a layered inorganic filler. In addition, the invention provides a process for preparing said coating composition. Moreover, the invention relates to the use of said-coating in an antifouling paint, fouling-release paint or in a biomedical and hygienic application. Further, the invention provides an antifouling paint or a fouling-release paint and a medical device comprising said coating composition. | 01-21-2010 |
20100291324 | COPY PROTECTED PAPER - The invention is directed to copy protected paper, to a method for producing said paper, the use of a specific layer for copy protection of paper, and a method for protecting a printable paper from being copied. Copy protected paper comprising a printable paper having, on a side to be printed or a printed side, a first transparent layer, wherein said first transparent layer has a difference in refractive index with i) said paper; or ii) an optional second transparent layer being provided on said paper on the side to be printed or the printed side, wherein said difference in refractive index is at least 0.05. | 11-18-2010 |
20100304154 | METHOD FOR PREPARING AN INORGANIC CRYSTALLINE CERAMIC MATERIAL HAVING AN ORGANIZED STRUCTURE - The present invention provides a method for preparing an inorganic crystalline ceramic material having an organized structure, comprising the steps of:
| 12-02-2010 |