Pine, US
Corey Pine, Juniper, FL US
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20140179681 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT - Provided herein are compounds having anti-proliferative effect. Also provided are compounds that can modulate the activity of multi-domain proteins comprising a dimerization arm and interdomain tether, such as EGFR, where an untethered, extended conformation is the active state and a tethered conformation is the inactive state, resulting in an autoinhibited configuration. Also provided are methods and pharmacophores for identifying such compounds. Other aspects provide methods or therapeutic treatment for proliferative diseases, disorders, or conditions, such as those associated with EGFR. | 06-26-2014 |
David Pine, New York, NY US
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20100090180 | SELF-REPLICATING MATERIALS - The invention provides micron and sub-micron scale particles designed to recognize and selectively interact with each other by exploiting the recognition and specificity enabled by DNA-sequence-encoded coatings. Such materials possess sufficient information coded in their chemical and physical interactions to self assemble and self replicate. The invention further provides methods of using such materials to create self replicating and organizing materials. Replicated copies are permanently linked and then thermally detached, freeing them to act as templates for further growth. This new class of condensed matter systems, provides means to design and control the structure and function of materials and machines from the microscopic to life-size. In another aspect of the invention, depletion type forces and depletion zones can be utilized in the implementation of the self assembly and self replication of materials, including without limitation colloidal particles. The invention further provides novel means of synthesis and materials built by such synthesis, which may be used in a variety of applications, including microelectronics. | 04-15-2010 |
20130278743 | METHOD AND SYSEM FOR MEASURING POROSITY OF PARTICLES - A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium. | 10-24-2013 |
David J. Pine, New York, NY US
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20120326088 | LOCK AND KEY COLLOIDS AND METHODS OF MANUFACTURE - A method and system for assembling building blocks of colloidal particles and also for shaping of colloids for self-assembly for manufacturing, processing and formation of compositions of matter. A first type of particle is selected as a “key” particle constructed to mate with a “lock” particle, the binding arising from depletion forces. A variety of shapes can be used to carry out this method and system to create compositions of matter. Colloids can be shaped by controlled deformation of multiphase colloid particles. | 12-27-2012 |
20140343181 | LOCK AND KEY COLLOIDS AND METHODS OF MANUFACTURE - A method and system for assembling building blocks of colloidal particles and also for shaping of colloids for self-assembly for manufacturing, processing and formation of compositions of matter. A first type of particle is selected as a “key” particle constructed to mate with a “lock” particle, the binding arising from depletion forces. A variety of shapes can be used to carry out this method and system to create compositions of matter. Colloids can be shaped by controlled deformation of multiphase colloid particles. | 11-20-2014 |
Gregory Pine, Hermitage, TN US
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20140056117 | SYSTEM AND METHOD FOR USING STAINLESS STEEL AS A DATA ARCHIVING MEDIUM - An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium. | 02-27-2014 |
20150078147 | SYSTEM AND METHOD FOR USING STAINLESS STEEL AS A DATA ARCHIVING MEDIUM - An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium. | 03-19-2015 |
James J. Pine, Tupelo, MS US
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20090031494 | Sleep sofa wherein seat and back cushions provide bedding surface - A sleep sofa includes a main frame, a seat unit, a back unit and a supporting linkage assembly that can move the back unit along an arc to the front of the seat unit when the sleep sofa is converted to a bed state, the supporting linkage simultaneously lifting the rear side of the seat unit, which is mounted in the main frame to slope downwardly from horizontal at about a 50 angle, up to horizontal. Once positioned in front of the seat unit, the back unit can be pushed downwardly so as to rotate into a locked parallel orientation with the seat unit. The seat cushion of the seat unit and the back cushion of the back unit form the bedding surface. Pushing a back release tube will unlock the back unit to allow it to be returned to a sitting positioning above the seat unit (tilted rearwardly to define an angle of about 115° with the seat unit). During its arc movement over the seat unit, the back unit will rotate around pivots on the side backs thereof. | 02-05-2009 |
Jarred Pine, Seattle, WA US
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20100169487 | DYNAMIC DATA PROCESSING APPLICATIONS WITH MULTIPLE RECORD TYPES AND WORK MANAGEMENT - Methods and apparatuses for defining and executing dynamic applications are disclosed herein. In various embodiments, an electronic library of work management entities is provided. In various embodiments, components are also provided to enable definition of a plurality of record types, definition of a plurality of relationships between selected ones of the work management entities and the record types, including one or more parent-child, reference and reciprocal relationships between selected ones of the record types, to form a dynamic application. In various embodiments, the components are also configured to enable definition of one or more capabilities for a record type, data phasing and workflow manage for the various record types. Other embodiments may also be described and claimed. | 07-01-2010 |
20100169859 | DYNAMIC DATA PROCESSING APPLICATIONS WITH DATA PHASING AND WORK MANAGEMENT - Methods and apparatuses for defining and executing dynamic applications are disclosed herein. In various embodiments, an electronic library of work management entities is provided. In various embodiments, components are provided to enable definition of a plurality of record types, definition of a plurality of data phases for a business lifecycle, behaviors of the record types and selected ones of the work management entities in the various data phases, and workflow rules for the record types and the work management entities to flow through the data phases. The selected ones of the work management entities, the record types, the data phases, behaviors of the record types and the selected ones of the work management entities in the various data phases, and workflow rules for the record types and the selected ones of the work management entities to flow through the data phases, form a dynamic application. Other embodiments may also be described and claimed. | 07-01-2010 |
Jeffrey A. Pine, Auburn, NY US
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20090045261 | Method For Providing User Feedback In An Autoidentification System - An optical barcode and/or RFID reader having at least two sets of illuminating LEDs that are directed toward a target object to reflect whether the barcode and/or RFID reading was successful or unsuccessful. The reader is provided with a set of red LEDs and a set of green LEDs for illuminating targets, such as barcodes or RFID tags. In addition to using these LEDs to illuminate the target, the reader will illuminate the target with a particular color of light to signify a successful read, such green light, or an unsuccessful read, such as red light. A third color may be provided to indicate a successful RFID interrogation, such as blue light. The reader thus uses the built-in illumination LEDs to cast differently colored light on the target, rather than having to provide additional LEDs in a user interface positioned on the housing of the reader. | 02-19-2009 |
20090173791 | System and method for logo identification and verification - A system for automatically identifying a logo or trademark applied to a device and verifying that the logo or trademark is acceptably identifies a compatible device. The system uses an optical imager to capture optical images of the target device and a microcontroller interconnected to the imager for processing the optical image to extract image information and verify that the contents of the image reflect the appropriate manufacturer or supplied indicia required by a host device. The decision reached by the microcontroller may be provided externally to a host device, thereby precluding or allowing use of the device, or provided directly to a user via know means, such as a visual display or audible output. | 07-09-2009 |
20110017828 | HANDHELD OPTICAL IMAGING DEVICE AND METHOD - A handheld optical imaging reader having a body specifically configured to be held in the hand and improve the ease by which a user can effectively obtain information from target objects presented to the reader. The body of the reader extends along a first axis and includes an optical imager aligned along a non-parallel second axis and a display extending along a non-parallel plane. The reader includes two triggers mounted to opposing sides of the body and positioned for activation by the thumb of a user when held in either the left of right hand using either an overhand or underhand grip. The reader may include a display and keypad to allow for high-level user functions and interaction. | 01-27-2011 |
Jeffrey Augustus Pine, Auburn, NY US
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20090065581 | Automated System For Verifying Electronic Election Results - A reader for automatically reading electronic voting machine paper audit records containing voting information encoded into barcodes printed on the audit records. The reader includes an optical imager for capturing images of barcodes printed on the audit records and a sensor for triggering the capture of images at the appropriate time. The reader further includes a drive mechanism for automatically advancing the audit records and stopping the records at the appropriate location so that the barcodes containing the voting information may be decoded. The reader is programmed to decode and interpret the encoded voting information and then provide the information to a host device. Once receipt of the information by the host has been confirmed, the reader automatically advances the audit record and repeated the decoding process. | 03-12-2009 |
Jerrold Scott Pine, Boca Raton, FL US
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20090124945 | High Efficiency Water Pick Cleaning Apparatus and Showerhead - The inventive pulsating water pick is used in combination with a pulsating showerhead supplied with pressurized water. The showerhead includes rotatable impeller periodically blocking water flow to a fixed regulator plate having circumferentially spaced apart groups of holes. A rotatable control plate—showerhead ejector face plate therebeneath has at least one opening sized to expose one group of holes. Raised lands limit water flow between adjacent plates and depressed areas lead to peripheral shower holes in a peripheral channel. The control plate rotates and plate openings expose hole groups in one mode, but in another, holes are blocked and water flows to depressed areas and the peripheral shower holes in the peripheral channel. The improved pulsating water pick includes a water passage port formed in the control plate and the showerhead ejector face plate, a coupler thereat leading to a tube, a water pick handle and a pick nozzle. | 05-14-2009 |
20100211027 | OPHTHALMIC DROP DISPENSING TIP ASSEMBLY - A dispensing tip apparatus for an eye drop dispenser to administer topical ophthalmic solutions is described. The apparatus integrates an ophthalmic solution-dispensing tip with an optical gauging assembly. The tip provides continuous visual feedback about it orientation and relationship to the eye. The dispensing tip when attached to any standard topical ophthalmic solution dispensing bottle or reservoir enables the user to view a target, visually align the dispenser tip, and administer an eye drop with precision. There is also a visual feedback by which the dispenser tip is prevented from gaining too close proximity and contacting the eye, thus preventing contamination of the medication and its dispenser. The visual feedback can also contain textual or graphic information that serves as a promotional advertisement. The is assembly can be attached to the neck of an eye drop bottle or attached to the tip of an eye drop bottle. | 08-19-2010 |
20110134600 | EZconnect Tablet/Stylus PC portable docking accessory with I/O ports - A portable docking accessory that contains an attachably detachable mechanically rigid means for providing a Tablet Pc user a host of I/O interconnect solutions that allows continuous mobile use in an ergonomic and aesthetically appropriate form factor. | 06-09-2011 |
Josh Pine, San Diego, CA US
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20090046002 | COMPACT RADAR TEST RANGE - A system for testing radar in accordance with one embodiment comprising a target motion platform; a target motion platform controller for controlling motion of the platform; a radar responsive tag and a delay line located on the target motion platform; the radar which is being tested; and a motion measurement simulator for inputting data to the radar electronics assembly to simulate movement of the radar. In some embodiments the system further comprises a radar motion platform, wherein the radar electronics assembly is positioned on the radar motion platform; a radar motion platform controller for controlling the movement of the radar motion platform; and a master controller coupled to the radar motion platform controller and the target motion platform controller. | 02-19-2009 |
Julie Hirshburg Pine, Murfreesboro, TN US
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20110015943 | COMPREHENSIVE METHOD AND SYSTEM FOR INTAKE SCREENING AND MEDICAL RECORDS MANAGEMENT - A system and method for providing health care services, such as medical intake screening and follow-up patient care, including management of medical records and access to patient information for incarcerated individuals. Data regarding medical information collected during an initial intake and screening process and subsequent physical examination may be inputted into a data repository. Triggers based upon the specific data entered may generate alerts for follow up medical care. | 01-20-2011 |
Mark Pine, Burbank, OH US
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20120325113 | METHOD FOR IMPROVEMENT OF CASTING QUALITY - Systems and methods for improved molding sand performance through use of recovered additives from the existing waste stream in a foundry. Sand, clay, and carbon-containing organic components are wet recovered from a green sand mold foundry dust recovery system. The sand and non-sand fractions may be further treated to reduce water content or adjust the levels of various components to generate a pre-mix additive for the generation of new green sand molds, that may display improved properties at ambient and high temperatures when compared to commonly employed traditional pre-mix. In some examples, pre-mixes having reduced sulfur content are obtained. In several embodiments, the non-sand fraction obtained from bag house dust or dust from mechanical reclamation includes increased levels of bentonite claim and carbon. | 12-27-2012 |
Matthew Pine, Gadsden, AL US
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20140144522 | PACKAGED AIR CONDITIONING SYSTEM HAVING Multiple UTILITY CONNECTIVITY - One aspect of this disclosure provides a packaged air conditioning & heating (PACH) system that comprises a housing, an air cooling system contained within the housing and an air heating system contained within the housing. A first utility access point is located on a first side of the housing and a second utility access point is located on a second side of the housing. The first and second utility access points provide multiple utility access connectivity for the air cooling and heating systems. | 05-29-2014 |
Matthew F. Pine, Allen, TX US
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20130166073 | METHOD FOR DETECTING PHYSICAL PRESENCE OF A SPECIFIC INDIVIDUAL TO CONTROL HVAC SETTINGS - A heating, ventilation and air-conditioning system includes a system controller configured to control the operation of a demand unit to maintain an environmental set point of a control zone. The system controller is further configured to control the demand unit in response to a location signal received from a location-reporting device. | 06-27-2013 |
Polly Pine, San Carlos, CA US
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20120232106 | TREATMENT FOR DISCOID LUPUS - Compounds I and II as well as salts and pharmaceutical compositions containing them are useful for treating diseases and/or disorders of the skin, such as cutaneous lupus, for example acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, or discoid lupus erythematosus. In certain embodiments, the compounds are provided in topical compositions. | 09-13-2012 |
Polly Pine, Menlo Park, CA US
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20130274277 | TREATMENT FOR DISCOID LUPUS - Compounds I and II as well as salts and pharmaceutical compositions containing them are useful for treating diseases and/or disorders of the skin, such as cutaneous lupus, for example acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, or discoid lupus erythematosus. In certain embodiments, the compounds are provided in topical compositions. | 10-17-2013 |
Richard Pine, New York, NY US
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20120315613 | ONLINE PLATFORM FOR LIFESTYLE MANAGEMENT - An online lifestyle management platform designed to address and manage the multiple factors affecting an individual's lifestyle is discussed. The lifestyle management platform may include an assessment evaluation tool used to establish a profile for an individual by assessing the individual's lifestyle factors. The lifestyle factors being assessed may include an individual's physical and mental condition, occupational and personal stress factors and goal satisfaction. Based on the profile, the lifestyle management platform generates a customized lifestyle management program such as a stress management program for the individual. | 12-13-2012 |
Samuel Pine, Emeryville, CA US
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20130315951 | COMPOSITIONS AND METHODS FOR STIMULATING AN IMMUNE RESPONSE AGAINST INFECTIOUS AGENTS - The invention provides for oral compositions for safely stimulating an immune response to mucoadhesive antigens for protection against infectious agents, particularly influenza viruses using heat-labile, mutant | 11-28-2013 |
Samuel Pine, Laguna Beach, CA US
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20090130141 | Compositions and methods for stimulating an immune response against infectious agents - The invention provides for oral compositions for safely stimulating an immune response to mucoadhesive antigens for protection against infectious agents, particularly influenza viruses using heat-labile, mutant | 05-21-2009 |
Shannon R. Pine, Evans, GA US
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20140277879 | Battery Electric Hybrid Drive For A Combine Harvester - A hybrid drive system for a combine includes a control wherein the hybrid system control determines a battery pack state-of-charge of the battery pack, and the hybrid system control also receives the current engine load estimate and engine speed from the engine control. Depending upon these variables, the hybrid control sends a torque command to a motor/generator control to provide a desired composite speed-torque curve from the engine and the motor/generator. In cases where the battery pack can be charged, an engine fuel curve is set by engine control to provide maximum engine power at isochronous speed, and when the battery pack is fully charged, the engine fuel curve is reduced to be shaped so that battery electric assist is not engaged until engine speed falls. | 09-18-2014 |
Sharon R. Pine, Neshanic Station, NJ US
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20130267029 | MANIPULATION OF STEM CELL FUNCTION BY P53 ISOFORMS - This invention provides methods and compositions for increasing the efficiency of obtaining pluripotent stem cells, the method comprising expressing a 133p53 in cells that are being re-programmed to obtain pluripotent cells. The invention also provides method of inhibiting the proliferation of cancer stem cells, the method comprising suppressing expression of 133p53 in the cells. | 10-10-2013 |