Mazzei
Daniele Mazzei, Pisa IT
Patent application number | Description | Published |
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20110129911 | Bioreactor Chamber - Embodiments of the invention provide a chamber for a bioreactor, the chamber having a fluid inlet aperture and a fluid outlet aperture disposed at respective different locations of a wall of the chamber, with respect to a normal upright orientation of the chamber the chamber being provided with an upper wall portion defining an upper boundary of the chamber. The upper wall portion has an internal surface having a first portion that is vertically displaced with respect to a second portion. The internal surface of the upper wall portion is arranged to promote expulsion of trapped gas bubbles through the outlet aperture, the first and second portions of the upper wall portion each comprising a sloped portion. | 06-02-2011 |
20110136218 | Bioreactor Chamber - Embodiments of the invention provide a bioreactor chamber assembly comprising: a bioreactor chamber comprising first and second portions arranged to be coupled to one another thereby to provide a liquid-tight seal therebetween; a pair of clamp members; and a pair of resilient loop elements, wherein the clamp members are arranged to sandwich the chamber between the clamp members and the loop elements are arranged to apply a force between the clamp members to urge the first and second portions together. | 06-09-2011 |
20130230907 | HIGH-THROUGHPUT SENSORIZED BIOREACTOR FOR APPLYING HYDRODYNAMIC PRESSURE AND SHEAR STRESS STIMULI ON CELL CULTURES - A bioreactor ( | 09-05-2013 |
David Mazzei, Columbus, OH US
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20130298352 | VEHICLE DOOR ADJUSTER AND METHOD - A method and system for mounting and adjusting a vehicle door rotatably connected to a vehicle body by upper and lower hinges with hinge holes. The upper and lower hinges are positioned to the vehicle body and the vehicle door by aligning the hinge holes to corresponding receiving holes. The vehicle door is temporarily mounted to the vehicle body by inserting cam bolts into aligned pairs of the hinge holes and the receiving holes. The vehicle door is adjusted to a desired position relative to the vehicle body by rotating the cam bolts. The desired positioned is secured by inserting mounting bolts into empty aligned pairs of the hinge holes and the receiving holes and replacing the cam bolts with mounting bolts. | 11-14-2013 |
20140053388 | DOOR STRIKER POSITIONER - A striker positioning assembly adjusts a striker mechanism on a door frame for latching a door. The striker positioning assembly includes a plate having a slot for receiving a projecting portion of the striker mechanism. The striker positioning assembly includes a fastener for temporarily fastening the plate to the door. The fastener allows for the plate to be removable after adjustment of the striker mechanism. The plate and slot are arranged such that closing the door into a desired position with respect to the door frame causes the striker positioning assembly to move the striker mechanism into a position on the door frame for latching the door in the desired position with respect to the door frame when the striker mechanism is secured on the door frame and when the striker positioning assembly is removed. Methods of adjusting the striker mechanism on the door frame are also provided. | 02-27-2014 |
20140182083 | METHOD OF ADJUSTING A VEHICLE DOOR - A method and system for mounting and adjusting a vehicle door rotatably connected to a vehicle body by upper and lower hinges with hinge holes. The upper and lower hinges are positioned to the vehicle body and the vehicle door by aligning the hinge holes to corresponding receiving holes. The vehicle door is temporarily mounted to the vehicle body by inserting cam bolts into aligned pairs of the hinge holes and the receiving holes. The vehicle door is adjusted to a desired position relative to the vehicle body by rotating the cam bolts. The desired positioned is secured by inserting mounting bolts into empty aligned pairs of the hinge holes and the receiving holes and replacing the cam bolts with mounting bolts. | 07-03-2014 |
Francesca Mazzei, Benson GB
Patent application number | Description | Published |
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20130066069 | PROCESSES FOR PREPARING SUBSTITUTED PYRIMIDINES - The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions. | 03-14-2013 |
Francesca Mazzei, Benson, Wallingford GB
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20100087467 | Compositions Useful As Inhibitors of Protein Kinases - The present invention provides compounds of formula I: | 04-08-2010 |
Francesca Mazzei, Abingdon GB
Patent application number | Description | Published |
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20090221602 | PROCESSES FOR PREPARING SUBSTITUTED PYRIMIDINES - The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions. | 09-03-2009 |
Francesca Ann Mazzei, Oxfordshire GB
Patent application number | Description | Published |
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20090291978 | Enzyme Inhibitors - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R | 11-26-2009 |
20100152155 | Histone Deacetylase Inhibitors - Compounds of formula: (I), and salts, N-oxides, hydrates and solvates thereof are histone deacetylase inhibitors and are useful in the treatment of cell proliferative diseases, including cancers: (I) wherein Q, V and W independently represent āNā or āCā; B is a divalent radical selected from: (IIA), (IIB), (IIC), (IID), and (IIE). Wherein the bond marked * is linked to the ring containing Q, V and W through -[Linker1]- and the bond marked ** is linked to A through -[Linker2]-; A is an optionally substituted mono-, bi- or tri-cyclic carbocyclic or heterocyclic ring system; and -[Linker1]- and -[Linker2]- independently represent a bond, or a divalent linker radical. | 06-17-2010 |
Francesca Ann Mazzei, Abingdon GB
Patent application number | Description | Published |
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20130116318 | Enzyme Inhibitors - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers: | 05-09-2013 |
20140163042 | ENZYME INHIBITORS - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R | 06-12-2014 |
Silvia Mazzei, Roma IT
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20120032835 | THREE-DIMENSIONAL TARGET TRACKING - The invention relates to a three-dimensional target tracking method comprising acquiring a first track generated by a first target location system having a first coverage area, said first track comprising a first position of a first target at a given time in a first relative reference system of the first target location system; acquiring a second track generated by a second target location system having a second coverage area partially overlapping the first coverage area in a coverage region shared by the two target location systems, said second track comprising a second position of a second target at the given time in a second relative reference system of the second target location system; and carrying out a correlation test and, if a same height is determined for the first and second targets, detecting that the first and second targets represent a same single target present in the shared coverage region. | 02-09-2012 |