Scherer
Andreas Scherer, Kontiolahti FI
Patent application number | Description | Published |
---|---|---|
20110189680 | Methods of Diagnosing Rejection of a Kidney Allograft Using Genomic or Proteomic Expression Profiling - A method of determining the acute allograft rejection status of a subject, the method comprising the steps of: determining the nucleic acid expression profile of one or more than one nucleic acid markers, or one or more than one proteomic markers in a biological sample from the subject; comparing the expression profile of the one or more than one nucleic acid markers to a control profile; and determining whether the expression level of the one or more than one nucleic acid markers is increased relative to the control profile, wherein the increase of the one or more than one nucleic acid markers is indicative of the acute rejection status of the subject. | 08-04-2011 |
Benjamin Scherer, Uster CH
Patent application number | Description | Published |
---|---|---|
20090149809 | OVERLAPPING DISPLAY - A device for administering an injectable product including a housing, a viewing element formed on or in the housing to create a view area, an emptying display movable inside and/or relative to the housing at least partially in or through the view area, and a view release member movable relative to the housing, wherein the visiability of the emptying display can be changed, reduced or eliminated by moving the view release member. | 06-11-2009 |
20100191217 | INJECTION DEVICE WITH A SPRING FOR A NEEDLE PROTECTING SLEEVE - An injection device including a housing, a needle guard sleeve displaceable relative to the housing, and a spring coupled to the guard sleeve such that the guard sleeve can be moved by the spring distally from a proximal position to an end position, the spring also being coupled to a forward drive element displaceable relative to the housing in a drive direction wherein the spring is tensioned upon a movement of the forward drive element in the forward drive direction. | 07-29-2010 |
20130218094 | AUTO-INJECTOR WITH ACTIVE AGENT CONTAINER LATCHING - In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors which are sold or distributed filled and with the springs tensed have to be provided with a needle protecting cap to ensure the sterility of the injection needle. When such a needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container comprising the injection needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve which accommodates the active agent container. When the auto-injector is placed onto a person's skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange and, thus, freeing the travel path for needle movement. | 08-22-2013 |
20150112273 | AUTO-INJECTOR WITH ACTIVE AGENT CONTAINER LATCHING - In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors which are sold or distributed filled and with the springs tensed have to be provided with a needle protecting cap to ensure the sterility of the injection needle. When such a needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container comprising the injection needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve which accommodates the active agent container. When the auto-injector is placed onto a person's skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange and, thus, freeing the travel path for needle movement. | 04-23-2015 |
20160074585 | INJECTION DEVICE WITH A SPRING FOR A NEEDLE PROTECTING SLEEVE - An injection device including a housing, a needle guard sleeve displaceable relative to the housing, and a spring coupled to the guard sleeve such that the guard sleeve can be moved by the spring distally from a proximal position to an end position, the spring also being coupled to a forward drive element displaceable relative to the housing in a drive direction wherein the spring is tensioned upon a movement of the forward drive element in the forward drive direction. | 03-17-2016 |
Christian Scherer, Roehrmoos DE
Patent application number | Description | Published |
---|---|---|
20140298772 | MISCHVORRICHTUNG UND TURBOFANTRIEBWERK MIT EINER DERARTIGEN MISCHVORRICHTUNG - The invention relates to a mixing device and a turbofan engine having such a mixing device | 10-09-2014 |
20150226155 | THRUST DEFLECTING DEVICE AND AIRCRAFT ENGINE - A thrust deflecting device for deflecting a thrust stream is disclosed, which includes a flap system having a plurality of deflecting flaps, each of which is pivotable around its yaw axis, the flap system being situated between parallel control surfaces such as baffle plates which, together with the flap system, form a box structure, which is pivotable around a pivot axis running in the direction of the transverse axis for the purpose of deflecting the thrust stream in the pitch direction, an aircraft engine also being disclosed. | 08-13-2015 |
Christopher Scherer, Deining DE
Patent application number | Description | Published |
---|---|---|
20150047600 | Method for Operating an Internal Combustion Engine - A method for operating an internal combustion engine of a motor vehicle involves directly injecting fuel into a combustion chamber using an injection device, and a mixture of the fuel and air is ignited in the combustion chamber by an ignition device. The internal combustion engine is operated selectively in at least one first operating mode with at least one first valve lift of at least one gas exchange valve of the internal combustion engine, associated with the combustion chamber, or in at least one second operating mode with at least one second valve lift of the gas exchange valve, which is smaller than the first valve lift. For assisting a charge movement of the mixture in the second operating mode, at least one further injection of fuel directly into the combustion chamber is carried out prior to the ignition. | 02-19-2015 |
Daniel Andreas Scherer, Birmensdorf CH
Patent application number | Description | Published |
---|---|---|
20150136836 | Through-Type Furnace For Substrates To Be Fitted With Components And Die Bonder - A through-type furnace for substrates comprises a furnace with a channel and a transport system for the transport of the substrates through the channel. The channel is bounded by a base, a front side wall, a rear side wall and a top part. The base contains a plurality of first holes which are connectable to a protective gas source so that protective gas can be supplied during operation. The front side wall of the channel comprises a longitudinal slit which extends parallel to the passage direction and which is bounded by a bottom edge and an upper edge. The transport system comprises at least one clamp for transporting the substrates through the channel. The clamp is movable back and forth along the longitudinal slit of the channel. Such a through-type furnace is in particular suitable for use in a soft solder die bonder. | 05-21-2015 |
Dieter Scherer, Laufen CH
Patent application number | Description | Published |
---|---|---|
20140100180 | TOPICAL PHARMACEUTICAL COMPOSITION BASED ON SEMIFLUORINATED ALKANES - The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages. Various active ingredients may be incorporated, such as immunosuppressants, antiinfectives, antifungal agents, antiinflammatory agents, and retinoids. | 04-10-2014 |
20140369993 | STABILISED PROTEIN COMPOSITIONS BASED ON SEMIFLUORINATED ALKANES - The invention provides novel compositions of bioactive polypeptides and proteins with improved stability and shelf-life. The compositions are based on liquid vehicles selected from semifluorinated alkanes. These vehicles are remarkably effective in protecting polypeptides and proteins from degradation and/or aggregation. The compositions are useful for topical administration, e.g. into an eye, or by parenteral injection, e.g. via the subcutaneous or intramuscular route. | 12-18-2014 |
20150224064 | COMPOSITIONS COMPRISING MIXTURES OF SEMIFLUORINATED ALKANES - The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions. | 08-13-2015 |
20150238605 | SEMIFLUORINATED ALKANE COMPOSITIONS - The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions. | 08-27-2015 |
Dominik Hermann Scherer, Horw CH
Patent application number | Description | Published |
---|---|---|
20100087426 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS - This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations. | 04-08-2010 |
20140024834 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS - This application discloses a process to synthesize 8-({1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy)-methyl]-8-pheny-1.7-diaza-spiro[4.5]decan-2-one comprising reacting a compound of the Formula 27a-sulfonate with zinc in the presence of acetic acid. | 01-23-2014 |
Guenther G. Scherer, Haegglingen CH
Patent application number | Description | Published |
---|---|---|
20080199754 | Method for Preparing a Radiation Grafted Fuel Cell Membrane with Enhanced Chemical Stability and a Membrane Electrode Assembly - In a method for preparing a membrane to be assembled in a membrane electrode assembly, such as a polymer electrolyte membrane fuel cell, a base polymer film is irradiated with at least one of electromagnetic and particle radiation in order to form reactive centers within the polymer film. The irradiated film is exposed to a mixture of monomers amenable to radical polymerization to form a graft copolymer in the irradiated film. The mixture includes α-methylstyrene and methacrylonitrile. The grafted film is sulfonated to introduce sulfonic acid sites providing ionic conductivity of the material. | 08-21-2008 |
20080318089 | Fast Locally Resolved Electrochemical Impedance Spectroscopy in Polymer Electrolyte Fuel Cells - A fuel cell, such as a polymer electrolyte fuel cell, includes an anode reactant supply plate, an anode current collector, a cathode reactant supply plate, and a cathode current collector. At least one of the anode reactant supply plate, the cathode reactant supply plate, the anode current collector and the cathode current collector is electrically separated into a number of segments, wherein each segment of at least a subgroup of segments is separately connected to an electronic drive and analysis circuitry which performs in parallel impedance measurement in a frequency range of 0.1 mHz to 50 kHz of the respective segments. | 12-25-2008 |
20090053611 | Method for Preparing a Membrane to Be Assembled in a Membrane Electrode Assembly and Membrane Electrode Assembly - A membrane electrode assembly includes a cathode layer, an anode layer, and a polymer electrolyte sandwiched between the cathode layer and the anode layer. The polymer electrolyte layer is a polymer film having a plurality of sections. The sections are radiation grafted and sulfonated, wherein the sections are separated from each other by separation bands. The separation bands are untreated sections of the polymer electrolyte layer. | 02-26-2009 |
Helmut Scherer, Taipei TW
Patent application number | Description | Published |
---|---|---|
20160119458 | CLAMP DEVICE - A clamp device for carrying a communication device comprises a compartment and a clamp. The compartment has a flat surface. The clamp is pivotally connected to the compartment and has a pressing line for contacting a surface edge of the communication device to fix the communication device on the compartment. | 04-28-2016 |
Joerg Scherer, Zuchwil CH
Patent application number | Description | Published |
---|---|---|
20140066730 | SYSTEM FOR IN-VIVO MEASUREMENT OF AN ANALYTE CONCENTRATION - The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display. | 03-06-2014 |
Josef Scherer, Brunnen CH
Patent application number | Description | Published |
---|---|---|
20120238163 | REINFORCING MESH FOR A REINFORCED MORTAR LAYER OR SPRAYED MORTAR LAYER ON AN UNDERLAYMENT, AND METHOD FOR THE INSTALLATION THEREOF AND REINFORCED MORTAR COATING PRODUCED THEREWITH - A reinforcing mesh for a reinforced mortar or sprayed mortar layer on an underlayment. The reinforcing mesh includes carbon fibers extending only in a marked direction as a special feature and together with inexpensive stabilising fibers made of glass or polyester which extend in one or more other directions, the reinforcing mesh forms a woven fabric, a scrim or a knitted fabric. The reinforcing mesh can be layed by roughening the surface of the underlayment; applying a leveling layer of cementitious mortar to the roughed surface of the underlayment; fastening the reinforcing mesh by processing the reinforcing mesh into the wet, not yet set leveling layer; and applying a cover layer of the identical cementitious mortar to the wet, not yet set, reinforced leveling layer. | 09-20-2012 |
20150218797 | Anchoring system for a bearing ground in the building industry as well as procedure for applying the same - Anchoring system is appropriate for solid rock and concrete ( | 08-06-2015 |
Karin Scherer, Charenton Le Pont FR
Patent application number | Description | Published |
---|---|---|
20100183857 | Optical Article Coated with an Antireflection Coating Comprising a Sublayer Partially Formed under Ion Assistance and Manufacturing Process - The invention relates to an optical article provided with antireflection properties, comprising a substrate having at least one main surface coated with an antireflection coating comprising, starting from the substrate: | 07-22-2010 |
20120013845 | Optical Article Coated with an Antireflection or Reflective Coating Comprising an Electrically Conductive Film Based on Tin Oxide, and Production Method - This invention relates to an optical article having antistatic and antireflection or reflective properties, comprising a substrate having at least one main surface coated with an antireflection or reflective coating, said coating comprising at least one electrically conductive layer comprising at least 30% tin oxide (SnO | 01-19-2012 |
20120328776 | PROCESS FOR THE MANUFACTURE OF LENSES - Process for manufacturing of an optical article which comprises: | 12-27-2012 |
20140354945 | ARTICLE COATED WITH AN INTERFERENCE COATING HAVING PROPERTIES THAT ARE STABLE OVER TIME - The invention relates to an article comprising a substrate having at least one main surface coated with a multilayer interference coating, said coating containing a layer A having a refractive index less than or equal to 1.55. The article is characterised in that: layer A forms either the outer interference coating layer or an intermediate layer that is in direct contact with the outer interference coating layer, said outer interference coating layer being a layer B having a refractive index less than or equal to 1.55; layer A is obtained by ion beam deposition of activated species from at least one compound C in gaseous form and containing in its structure at least one silicon atom, at least one carbon atom, at least one hydrogen atom and, optionally, at least one nitrogen atom and/or at least one oxygen atom, layer A being deposited in the presence of nitrogen and/or oxygen when compound A does not contain nitrogen and/or oxygen; and layer A is not formed from inorganic precursor compounds. | 12-04-2014 |
Karin Scherer, St Maur Des Fosses FR
Patent application number | Description | Published |
---|---|---|
20160024643 | Method for depositing an amorphous layer primarily containing fluorine and carbon, and device suited for carrying out this method - A method for depositing, under vacuum, an amorphous layer primarily containing fluorine and carbon onto a substrate ( | 01-28-2016 |
Kathrin M. Scherer, Losheim Am See DE
Patent application number | Description | Published |
---|---|---|
20150359884 | MULTI-PHOTON ISOMERISATION OF COMBRETASTATINS AND THEIR USE IN THERAPY - Combretastatins and their use in treating conditions characterised by abnormal vasculature or cancer by irradiation of the combretastatin in situ, and kits comprising such compounds. | 12-17-2015 |
Klaus Scherer, Ruesselsheim DE
Patent application number | Description | Published |
---|---|---|
20150321300 | PRODUCTION LINE FOR MACHINING AT LEAST ONE SURFACE COMPONENT AND METHOD FOR MACHINING THE AT LEAST ONE SURFACE COMPONENT IN THE PRODUCTION LINE - A production line for machining a surface component with a first machining station and a second machining station is disclosed. The first machining station includes a separating device configured to separate a surface component along a machining path. The second machining station includes a bending/forming device configured to form and/or bend the surface component in a bending/forming position. The first machining station and the second machining station are sequentially arranged one directly after the other and/or linked together. | 11-12-2015 |
Michael Scherer, Schallstadt-Mengen DE
Patent application number | Description | Published |
---|---|---|
20150219260 | HOSE COUPLING - A hose coupling is sleeve-shaped form and which, at at least one coupling end, has a connector with a retention profiling provided on the outer circumference at least in one connector subregion, onto which at least one profiled coupling end a hose end of a flexible hose can be pushed. The hose coupling according to the invention is characterized in that the retention profiling is formed by at least one retention groove which is provided on the outer circumference of the connector and which has groove long sides oriented in the connector circumferential direction and groove narrow sides oriented in the connector longitudinal direction. | 08-06-2015 |
20150226356 | HOSE COUPLING - A hose coupling is sleeve-shaped form and which, at at least one coupling end, has a connector with a retention profiling provided on the outer circumference at least in one connector subregion, onto which at least one profiled coupling end a hose end of a flexible hose can be pushed. The hose coupling according to the invention is characterized in that the retention profiling is formed by at least one retention groove which is provided on the outer circumference of the connector and which has groove long sides oriented in the connector circumferential direction and groove narrow sides oriented in the connector longitudinal direction. | 08-13-2015 |
Paul Martin Scherer, Walchwil CH
Patent application number | Description | Published |
---|---|---|
20130090389 | Polyethylene Glycol Compositions for Controlling Relapse of Herpes Labialis, Herpes Genitalis, and Herpes Zoster - The present invention pertains generally to the field of therapy, and more specifically to the field of therapy for herpes simplex and herpes zoster, and more particularly, to methods of reducing the rate of relapse, delaying relapse, and/or preventing relapse of herpes labialis (cold sores on the lips), herpes genitalis (genital herpes), and herpes zoster (shingles, zona), by topical administration of polyethylene glycol (PEG), or a composition comprising PEG. | 04-11-2013 |
Stefan Scherer, Basel CH
Patent application number | Description | Published |
---|---|---|
20120195858 | RESPONSIVENESS TO ANGIOGENESIS INHIBITORS - The present invention relates to methods for improving the overall survival of a patient suffering from a malignant disease or a disease involving physiological and pathological angiogenesis by treatment with an angiogenesis inhibitor, such as bevacizumab, by determining the presence of one or more variant alleles of the vascular endothelial growth factor receptor 1 (VEGFR-1) gene. The present invention further provides methods for improving the progression-free survival of a patient suffering from a malignant disease or a disease involving physiological and pathological angiogenesis by treatment with an angiogenesis inhibitor, such as bevacizumab, by determining the presence of one or more variant alleles of the VEGFR-1 gene. The present invention also provides for methods for assessing the responsiveness of a patient to an angiogenesis inhibitor by determining the presence of one or more variant alleles of the VEGFR-1 gene. | 08-02-2012 |
20140099302 | METHODS TO IDENTIFY RESPONSIVE PATIENTS - The present invention provides methods and kits for improving the progression-free survival of a patient suffering from gastrointestinal cancer and for assessing the sensitivity or responsiveness of the patient to treatment comprising bevacizumab. | 04-10-2014 |
Stefan Scherer, Edmonton CA
Patent application number | Description | Published |
---|---|---|
20110033287 | BLOWER SCROLL HAVING AN ASPIRATOR VENTURI - A blower assembly for use with an HVAC module is provided. The blower assembly includes a scroll or volute shaped housing having an air inlet in a wall of the housing for receiving air to be blown by an impeller, and an air outlet from which the blown air passes from the housing. A blower wheel is secured to a rotatable motor-driven shaft extending along a central axis of the air inlet. At least one venture is provided adjacent to the air inlet of the housing, the at least one venturi connectable to an aspirator that is in fluid communication with a sensor unit. Wherein, during operation, the blower wheel pulls air both through the air inlet to the housing and through the at least one venturi. | 02-10-2011 |
Stefan Scherer, Preverenges CH
Patent application number | Description | Published |
---|---|---|
20140294768 | RESPONSIVENESS TO ANGIOGENESIS INHIBITORS - The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determining the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGF promoter gene and/or VEGFR2 gene. | 10-02-2014 |
20140294811 | METHOD FOR PREDICTING RISK OF HYPERTENSION ASSOCIATED WITH ANTI-ANGIOGENESIS THERAPY - The invention is concerned with a method of predicting a patient's susceptibility to developing hypertension associated with an anti-angiogenesis treatment, such as bevacizumab, by determining the genotype of KDR gene and/or EGF gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of KDR gene and/or EGF. The invention further relates to a method for reducing the risk of hypertension associated with an anti-angiogenesis therapy, such as bevacizumab, in a patient suffering from cancer by determining the genotype of KDR gene and/or EGF gene. | 10-02-2014 |
20140341893 | BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER - The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer, by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of VEGFA and/or VEGFR2 relative to control levels of patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer. The present invention also provides for methods for assessing the sensitivity or responsiveness of a patient to bevacizumab (Avastin®) in combination with a chemotherapy regimen, by determining the expression level, in particular the blood plasma expression level, of VEGFA and/or VEGFR2 relative to control levels in patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer. | 11-20-2014 |
Stefan Scherer, Ottawa CA
Patent application number | Description | Published |
---|---|---|
20090288137 | Distributed Digital Rights Management System and Method - A digital rights management system includes an authentication module and a decryption module. If desired, the modules can be implemented in separate integrated circuits. The authentication module retrieves authentication information for protected content and powers down after the authentication information is retrieved. The decryption module decrypts the protected content based on the authentication information while the authentication module is powered down. | 11-19-2009 |
Stefan Scherer, Graz AT
Patent application number | Description | Published |
---|---|---|
20130113896 | ESTIMATION OF DEFOCUSED REFLECTANCE MAPS FOR THE ROBUST DETERMINATION OF "SHAPE FROM FOCUS" IN MICROSCOPIC IMAGES - Method for compensating illumination deficiencies in microscopic “shape from focus (SFF)”, wherein firstly the reflectance of the scene is estimated by way of a projector-camera system and then microscopic “shape from focus (SFF)” is applied to a stack of reflectance maps rather than to the original image data. | 05-09-2013 |
Stefan Thomas Scherer, Ottawa CA
Patent application number | Description | Published |
---|---|---|
20090285390 | INTEGRATED CIRCUIT WITH SECURED SOFTWARE IMAGE AND METHOD THEREFOR - The various embodiments herein disclosed include a method wherein an integrated circuit ( | 11-19-2009 |
Stephen Scherer, Toronto CA
Patent application number | Description | Published |
---|---|---|
20120122725 | Method of determining risk of a neuropsychiatric disorder - A method of assessing risk of ADHD in a human subject is provided. The method comprises the step of identifying in a nucleic acid-containing sample obtained from the human subject copy number variations associated with one or more genes selected from the group consisting of DCLK1, DCLK2, SORCS3, SORCS1, 16p11.2, ASTN2, MACROD2, CHCHD, CPLX2, ZBBX, PTPRN2 and TRIM32 wherein a determination of copy number variations associated with one or more of said genes is indicative of a risk of ADHD in the human subject. | 05-17-2012 |
20130210657 | Method of Determining Risk of Autism Spectrum Disorder - A method of assessing risk in a human subject of ASD is provided comprising the step of identifying in a nucleic acid-containing sample obtained from the human subject copy number variations associated with SHANK1. Determination of copy number variations associated with SHANK1 is indicative of a risk of ASD in the human subject. | 08-15-2013 |
20130316911 | METHODS AND COMPOSITIONS FOR SCREENING AND TREATING DEVELOPMENTAL DISORDERS - This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder. | 11-28-2013 |
20140161721 | Methods And Compositions For Screening And Treating Developmental Disorders - This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder. | 06-12-2014 |
Stephen W. Scherer, Toronto CA
Patent application number | Description | Published |
---|---|---|
20100009346 | Lafora's disease gene - A novel gene (EPMZA) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EMP2A have been found that co-segregate with Lafora's disease. | 01-14-2010 |
20100248235 | BIOMARKERS FOR AUTISM SPECTRUM DISORDERS - Methods of determining the risk of ASD in an individual are provided which comprise identifying the presence of one or more genomic mutations in one or more of the genes, PTCHD1, SHANK3, NFIA, DPP6, DPP10, DYPD, GPR98, PQBP1, ZNF41 and FTSJ1. | 09-30-2010 |
20120070826 | LAFORA'S DISEASE GENE - A novel gene (EPM2B) that is mutated in humans and dogs with Lafora's disease is described. | 03-22-2012 |
20120100995 | Biomarkers for Autism Spectrum Disorders - Methods of determining the risk of ASD or ID in an individual are provided which comprise identifying the presence of one or more specific genomic mutations in, upstream of, or comprising the PTCHD1 gene. Additionally provided are methods of determining the risk of ASD or ID in an individual comprising analyzing genomic mutations in PTCHD1AS1 and/or PTCHD1AS2 and/or PTCHD1AS3. | 04-26-2012 |
20140057971 | LaFORA'S DISEASE GENE - A novel gene (EPM2A) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EPM2A have been found that co-segregate with Lafora's disease. | 02-27-2014 |
20140072970 | LAFORA'S DISEASE GENE - A novel gene (EPM2B) that is mutated in humans and dogs with Lafora's disease is described. | 03-13-2014 |
20150322518 | BIOMARKERS FOR AUTISM SPECTRUM DISORDERS - Methods of determining the risk of ASD in an individual are provided which comprise identifying the presence of one or more genomic mutations in one or more of the genes, PTCHD1, SHANK3, NFIA, DPP6, DPP10, DYPD, GPR98, PQBP1, ZNF41 and FTSJ1. | 11-12-2015 |
Taco Scherer, Haarlem NL
Patent application number | Description | Published |
---|---|---|
20110212267 | COATING COMPOSITION COMPRISING A POLYISOCYANTE AND A POLYOL - The invention relates to a non-aqueous coating composition comprising a. a polyisocyanate, b. a polyol having an average functionality of more than 3 hydroxyl groups per molecule, c. a metal based curing catalyst for the addition reaction of isocyanate groups and hydroxyl groups, and d. a mercapto carboxylic acid, wherein the coating composition does not contain a carboxylic acid wherein the carbonyl group of the carboxylic acid is in conjugation with π-electron system. | 09-01-2011 |
20150017336 | NON-AQUEOUS LIQUID COATING COMPOSITION - The invention relates to a non-aqueous liquid coating composition comprising a) a polyol, b) a polyisocyanate crosslinker c) one or more thiol-functional compounds, d) a metal-based curing catalyst for catalyzing the addition reaction of isocyanate groups and hydroxyl groups, e) a base having a pKa value of at least 7, and which base does not react with isocyanate groups in a way wherein the basicity is reduced, and f) one or more acid group-containing compounds, wherein the one or more thiol-functional compounds are present in an amount to provide a molar ratio of thiol groups over the metal atoms of the metal-based curing catalyst of 1 or higher, and wherein the base is present in a molar amount lower than the molar amount of thiol groups, and wherein the molar ratio of acid groups and base groups is 1:1 or higher. | 01-15-2015 |
Thomas Scherer, Sempach CH
Patent application number | Description | Published |
---|---|---|
20110297049 | POWDER TO REDUCE SHRINKAGE OF MINERALLY BINDING MATERIALS - This invention relates to a powder comprising a carrier material which is in powdery form and selected from the group consisting of a water-soluble polymer, a water-insoluble polymer, and an inert inorganic material, and a mixture containing at least about 5 wt. % of a compound having the formula (1-a) and at least about 5 wt. % of a compound having the formula (1-b), HO—(R | 12-08-2011 |
20130131220 | EMULSION OR REDISPERSIBLE POLYMER POWDER OF A POLYMER COMPRISING A BIOMONOMER, A PROCESS TO PREPARE THEM, AND THE USE THEREOF IN BUILDING MATERIAL COMPOSITIONS - The present invention relates to process to prepare a polymer by an aqueous emulsion or suspension polymerisation process wherein a monomer mixture is polymerised in the presence of a free radical initiator and a stabiliser, to the emulsion and redispersible polymer powder obtainable therewith, and to the use of this emulsion and powder in a building material composition, in particular to hydrophobise the building material composition, wherein the monomer mixture comprises (i) 0.5-80 wt. % of biomonomers containing an ester of a polyol and at least one fatty acid, the polyol having 2 to 10 hydroxy groups, and at least one vinyl group; (ii) 20-99.5 wt. % of vinyl monomers chosen from the group of vinyl esters, (meth)acrylic esters, vinyl aromatic compounds, vinyl halides, and olefins; and (iii) 0 to 20 wt % of vinyl monomers that are different from monomer (ii) and contain at least one functional group chosen from the group of alkoxysilane, glycidyl, epoxy, epihalohydrin, nitrile, carboxyl, amine, ammonium, amide, imide, N-methylol, isocyanate, hydroxyl, thiol, keto, carbonyl, acid anhydride, aceto acetonate, sulfonic acid groups, and salts thereof, and the stabiliser comprises (a) 50 to 100 wt. % of a protective colloid; and (b) 0 to 50 wt. % of an emulsifier. | 05-23-2013 |
Thomas Scherer, Luedenscheid DE
Patent application number | Description | Published |
---|---|---|
20150210176 | Charging Device for Charging an Electric Vehicle at a Charging Station - A charging system for charging an electric vehicle at a charging station includes a charge module at the charging station and a charge module at the vehicle. The charge modules include electric contact elements which can be interconnected together. The charging system includes an automatic positioning device configured to move the charging station charge module relative to the vehicle charge module to align and join the charge modules together. The charging system includes an automatic feed device configured to enable the contact elements of the charging station charge module to connect to the contact elements of the vehicle charge module when the charge modules are joined together. The contact elements of the charge modules are configured such that the contact elements can connect to each other without overriding a contact force. | 07-30-2015 |
Volker Scherer, Koln DE
Patent application number | Description | Published |
---|---|---|
20150218687 | CYLINDER LINER AND METHOD FOR PRODUCING SAME - The invention relates to a method for producing a thermally sprayed, thin-walled cylinder liner for insertion into a cylinder crankcase and to a cylinder liner produced with said method. | 08-06-2015 |
20150240741 | CYLINDER SLEEVE WITH WEAR-RESISTANT INNER LAYER - The present invention relates to a cylinder liner with a covering layer, and a wear-resistant inner layer, arranged inside of the cylinder liner, wherein a thickness of the wear-resistant inner layer, decreases on at least one axial end of the cylinder liner. | 08-27-2015 |