Patent application number | Description | Published |
20090088399 | Use of Light Sensitive Genes - The invention relates to the use of a light-gated ion channel for the manufacture of a medicament for the treatment of blindness and a method for expressing said cell specific fashion, e.g. in ON-bipolar cells, ON-ganglion cells, or AII amacrine cells. | 04-02-2009 |
20110065093 | NOVEL TOOL FOR THE ANALYSIS OF NEURAL CIRCUITS - The application relates to an isolated transsynaptic virus expressing an exogenous fluorescent activity sensor. Preferably, the transsynaptic virus is a rhabdovirus, e.g. rabies virus, or a herpesvirus, preferably an alphaherpesvirus, e.g. pseudorabies virus. The fluorescent exogenous activity sensor used in the transsynaptic virus can be a fluorescent protein Ca | 03-17-2011 |
20120196281 | FUNCTIONALIZED ORGANOTYPIC SYSTEMS - The present invention provides an organotypic system comprising a portion of a retina containing live cells in a cultured in medium, wherein photosensitivity has been restored in at least some of said live cells. Methods of use thereof are also provided. | 08-02-2012 |
20130005795 | Use of Light Sensitive Genes - The invention relates to the use of a light-gated ion channel for the manufacture of a medicament for the treatment of blindness and a method for expressing said cell specific fashion, e.g. in ON-bipolar cells, ON-ganglion cells, or AII amacrine cells. | 01-03-2013 |
20140094506 | USE OF LIGHT SENSITIVE GENES - The invention relates to the use of a light-gated ion channel for the manufacture of a medicament for the treatment of blindness and a method for expressing said cell specific fashion, e.g. in ON-bipolar cells, ON-ganglion cells, or AII amacrine cells. | 04-03-2014 |
20140287510 | Rod cell-specific promoter - The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod cells of a gene when operatively linked to a nucleic acid sequence coding for said gene. | 09-25-2014 |
20150246094 | USE OF LIGHT SENSITIVE GENES - The invention relates to the use of a light-gated ion channel for the manufacture of a medicament for the treatment of blindness and a method for expressing said cell specific fashion, e.g. in ON-bipolar cells, ON-ganglion cells, or AII amacrine cells. | 09-03-2015 |
20150344907 | Retinal OFF circuit-specific promoter - The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene. | 12-03-2015 |
Patent application number | Description | Published |
20130174453 | WEAR ASSEMBLY - A wear assembly for use on various kinds of earth working equipment that includes a base with a supporting portion, a wear member with a cavity into which the supporting portion is received, and a lock to releasably secure the wear member to the base. The supporting portion is formed with top and bottom recesses that receive complementary projections of the wear member. These recesses and projections include aligned holes so as to receive and position the lock centrally within the wear assembly and remote from the wear surface. The lock includes a mounting component that defines a threaded opening for receiving a threaded pin that is used to releasably hold the wear member to the base. The separate mounting component can be easily manufactured and secured within the wear member for less expense and higher quality than forming the threads directly in the wear member. | 07-11-2013 |
20140215868 | WEAR ASSEMBLY - Wear members for wear assemblies include a lock configured to secure the wear member to a base, where the lock has two engagement positions, namely: (a) a first position that secures the lock to the wear member, and (b) a second position that secures the wear member to the base. The locks are further configured to be unlatched and removed from the wear member in two phases, a first retraction of the latching mechanism, followed by a rotation of the lock itself with removal from the wear member. | 08-07-2014 |
20150314297 | HAMMER FOR MATERIAL REDUCING MACHINES - A multi-piece hammer for use in a reducing machine. The multi-piece hammer includes a base to be mounted to the reducing machine, a replaceable tip to be mounted to the base and to impact the material to be reduced, and a retainer to secure the replaceable tip to the base. The replaceable tip has a cavity with a single rail or groove that corresponds to a single groove or rail on the base. | 11-05-2015 |
20150314298 | HAMMER FOR MATERIAL REDUCING MACHINES - A multi-piece shredder hammer for use in a reducing machine. The multi-piece shredder hammer includes a base to be mounted to the reducing machine, a replaceable tip to be mounted to the base and to impact the material to be reduced, and a retainer to secure the replaceable tip to the base. The replaceable tip is installed on the base from a side of the base. | 11-05-2015 |
Patent application number | Description | Published |
20100084431 | Self-Heating Material Dispenser - A dispensing unit, which utilizes a chemical reaction or phase transition to soften a material into a flowable state, is described. The material comprises an adhesive, sealant or caulk. | 04-08-2010 |
20100276057 | ETHYLENE-BUTENE COPOLYMER, ADHESIVE COMPOSITION INCLUDING THE SAME, AND METHOD OF MAKING AND USING THE SAME - An ethylene-butene copolymer prepared from ethylene monomer and butene monomer, the ethylene-butene copolymer including at least 78 mole % ethylene and no greater than 22 mole % butene, and a hot melt adhesive composition including from 40% by weight to 90% by weight of the ethylene-butene copolymer, tackifying agent, and wax. | 11-04-2010 |
20120329353 | OLEFIN BASED HOT MELT ADHESIVE COMPOSITIONS AND NONWOVEN AND PACKAGING ARTICLES INCLUDING THE SAME - A hot melt adhesive composition that includes a non functionalized metallocene catalyzed polymer and a second polymer selected from the group including amorphous poly alpha olefins, uni-modal metallocene catalyzed polymers, hydrogenated styrenic block copolymers and combinations thereof and nonwoven and packaging articles including the same. | 12-27-2012 |
20120329929 | FREE RADICAL INITIATOR MODIFIED HOT MELT ADHESIVE COMPOSITION INCLUDING FUNCTIONALIZED POLYETHYLENE AND PROPYLENE-ALPHA-OLEFIN POLYMER - A hot melt adhesive composition that includes a first copolymer that includes the reaction product of a functionalized polyethylene, a propylene-alpha-olefin polymer that includes at least 50 mole % propylene and has a viscosity of no greater than 10,000 centipoise at 190° C., a ratio of z average molecular weight (Mz) to number average molecular weight (Mn) (Mz/Mn) of greater than 20, and a ratio of Mz to weight average molecular weight (Mw) (Mz/Mw) of greater than 3.0, and a free radical initiator. | 12-27-2012 |