Kuno, US
Harumi Kuno, Palo Alto, CA US
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20150370644 | RECOVERING PAGES OF A DATABASE - Failure of storage media containing at least a portion of a database that has been backed up to backup media is detected. In response to detecting the failure, a log that includes transactions carried out with respect to the database is analyzed. Transactions that access the database are run prior to completion of recovery of the portion of the database from the backup media. Recovery of individual pages is carried out as the individual pages are accessed by the running transactions. | 12-24-2015 |
Harumi Anne Kuno, Cupertino, CA US
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20100082599 | Characterizing Queries To Predict Execution In A Database - One embodiment is a method that obtains query plans for queries in the workload. The query plans include a tree of operators and estimated cardinalities for nodes in the tree. The method then groups the operators for the queries and characterizes the workload in terms of grouped operators to predict performance of the queries before the queries execute in a database. | 04-01-2010 |
20100082602 | Predicting Performance Of Multiple Queries Executing In A Database - One embodiment is a method that generates query vectors from query plans and performance vectors from data collected while executing multiple queries in a database. A machine learning technique (MLT) computes distances between two query vectors and two performance vectors and then predicts performance of plural queries executing in the database. | 04-01-2010 |
20100082603 | Managing Execution Of Database Queries - One embodiment is a method to manage queries in a database. The method identifies a query that executes on the database for an elapsed time that is greater than a threshold and then implements a remedial action when the query executes on the database for an execution time that is greater than an estimated execution time. | 04-01-2010 |
20100114865 | Reverse Mapping Of Feature Space To Predict Execution In A Database - One embodiment is a method that generates points from an input space obtained from a query for a database. A kernel function maps the points from the input space to a feature space. Given a point in the feature space, a reverse mapping identifies coordinates in the input space for the point to predict performance of the query before the query executes in the database. | 05-06-2010 |
Harumi Anne Kuno, Palo Alto, CA US
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20100082507 | Predicting Performance Of Executing A Query In Isolation In A Database - One embodiment is a method that generates query vectors from query plans and performance vectors from data collected while executing queries in a database. The method then uses a machine learning technique (MLT) to compute distances between two query vectors and two performance vectors and to predict performance of executing a new single query in isolation in the database. | 04-01-2010 |
Junko Kuno, Holmes, NY US
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20150159174 | Methods and Compositions for the Targeted Modification of a Genome - Compositions and methods are provided for modifying a genomic locus of interest in a eukaryotic cell, a mammalian cell, a human cell or a non-human mammalian cell using a large targeting vector (LTVEC) comprising various endogenous or exogenous nucleic acid sequences as described herein. Further methods combine the use of the LTVEC with a CRISPR/Cas system. Compositions and methods for generating a genetically modified non-human animal comprising one or more targeted genetic modifications in their germline are also provided. | 06-11-2015 |
20150159175 | METHODS AND COMPOSITIONS FOR THE TARGETED MODIFICATION OF A GENOME - Compositions and methods are provided for modifying a genomic locus of interest in a eukaryotic cell, a mammalian cell, a human cell or a non-human mammalian cell using a large targeting vector (LTVEC) comprising various endogenous or exogenous nucleic acid sequences as described herein. Further methods combine the use of the LTVEC with a CRISPR/Cas system. Compositions and methods for generating a genetically modified non-human animal comprising one or more targeted genetic modifications in their germline are also provided. | 06-11-2015 |
Masaru Kuno, Granger, IN US
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20140273403 | LIGHT INDUCED NANOWIRE ASSEMBLY - The invention provides a method for assembling semiconducting nanowires, which method can include providing a mixture comprising a dielectric solvent and two or more semiconducting nanowires, wherein the semiconducting nanowires can be the same or different; exposing the mixture to an electrostatic charge under lighting conditions; and allowing macroscopic nanowire alignment to occur, wherein each nanowire is substantially oriented along the direction of the applied electric field. | 09-18-2014 |
Oji Kuno, Ann Arobor, MI US
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20090124491 | Catalyst Support Powder and Exhaust Gas Purifying Catalyst - The present invention provides a catalyst support powder | 05-14-2009 |
Sachiko Kuno, Potomac, MD US
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20090254449 | ACCESS METHOD OF REGULATORY APPROVING DATA FOR NETWORKED MULTILATERAL ALLIANCE - The invention achieves certain advantages in pharmaceutical development over large multinational companies by forming a multilateral alliance of independent entities, each with their own geographical focus. In accordance with the invention, a method is provided whereby multiple entities, within the coverage of a common patent portfolio, undertake their own research and development in their own territory. Under a second feature of the invention, the entities may each utilize the information obtained by the others in order to advance their own development program. | 10-08-2009 |
20100298424 | METHOD FOR TREATING ABDOMINAL DISCOMFORT - Disclosed is a novel use of a chloride channel opener, especially a prostaglandin compound for the treatment of abdominal discomfort. Further disclosed is a novel use of a chloride channel opener, especially a prostaglandin compound for the treatment of functional gastrointestinal disorders. | 11-25-2010 |
20130217770 | METHOD FOR TREATING IRRITABLE BOWEL SYNDROME BY ADMINISTRATION OF CHLORIDE CHANNEL OPENER - A chloride channel opener, especially a prostaglandin compound, is used for the treatment of functional gastrointestinal disorders. The prostaglandin compound can be, for example, a 13,14-dihydro-15-keto-16,16-difluoro-prostaglandin E | 08-22-2013 |
Sachiko Kuno, St Michaels, MD US
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20140371304 | METHOD FOR SUPPRESSING TUMORIGENICITY OF STEM CELLS - A method for suppressing tumorigenicity of stem cells in a mammalian subject, which comprises administering an effective amount of a fatty acid derivative and a method for suppressing tumorigenicity of stem cells of a mammalian subject, which comprises contacting said stem cell with an effective amount of a fatty acid derivative, are provided. | 12-18-2014 |
Sachiko Kuno, Easton, MD US
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20150099802 | SELECTIVE TUMOR TREATMENT - A method for treating a tumor with a decreased level of the 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) in a mammalian subject, which comprises administering to the subject in need thereof an effective amount of a fatty acid derivative, a method for suppressing the growth of a tumor cell with a decreased level of the 15-hydroxy-prostaglandin dehydrogenase (15-PGDH), which comprises contacting said tumor cell with an effective amount of a fatty acid derivative, and a method for identifying a subject who would be responsive to a fatty acid derivative, comprising, (i) obtaining a biological sample from said subject; and (ii) measuring 15-hydroxyprostaglandin dehydrogenase (15-PGDH) level are provided. | 04-09-2015 |
Sachiko Kuno, Montgomery, MD US
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20080207759 | METHOD FOR PROTECTING MITOCHONDRIA - The present invention relates to a method for protecting mitochondria from damage in a mammalian subject, which comprises administering an effective amount of a prostaglandin compound to a subject in need thereof. Also provided is a method for treating mitochondrial dysfunction as well as a condition associated with mitochondrial dysfunction in a mammalian subject, which comprises administering an effective amount of a prostaglandin compound to a subject in need thereof. | 08-28-2008 |
20090209643 | METHOD FOR MODULATING STEM CELL GROWTH - In one embodiment, provided is a composition comprising a prostaglandin compound for modulating stem cell proliferation and/or differentiation in a mammalian subject. In another embodiment, the instant application is a composition comprising a prostaglandin compound for, which comprises a prostaglandin compound for modulating proliferation and/or differentiation of stem cells of a mammalian subject, in which the stem cells are contacted directly or indirectly with the composition of the invention. | 08-20-2009 |