Spector, US
Alfred Zalmon Spector, Pelham Manor, NY US
Patent application number | Description | Published |
---|---|---|
20160063660 | PROTECTING CONTENT ON A MOBILE DEVICE FROM MINING - Systems and methods prevent or restrict the mining of content on a mobile device. For example, a method may include determining that content to be displayed on a screen includes content that matches a mining-restriction trigger, inserting a mining-restriction mark in the content that protects at least a portion of the content, and displaying the content with the mining-restriction mark on the screen. As another example, a method may include identifying, by a first application running on a mobile device, a mining-restriction mark in frame buffer data, the mining-restriction mark having been inserted by a second application, and determining whether the mining-restriction mark prevents mining of content. The method may also include preventing mining when the mining-restriction mark prevents mining and, when the mining-restriction mark does not prevent mining, determining a restriction for the data based on the mining-restriction mark and providing the restriction with the data for further processing. | 03-03-2016 |
Brian P. Spector, Seattle, WA US
Patent application number | Description | Published |
---|---|---|
20130042112 | USE OF NON-INTERACTIVE IDENTITY BASED KEY AGREEMENT DERIVED SECRET KEYS WITH AUTHENTICATED ENCRYPTION - A sender private key is created from a master key. The sender private key and public information about a recipient is used to produce a secret key. Data is encrypted with the secret key. The encryption uses authentication data. The encrypted data is sent to the recipient. A recipient private key is created from the master key. The recipient private key is different from the sender private key. The recipient private key and public information about the sender is used to recreate the secret key. At the recipient, the secret key is used to decrypt the encrypted data and the authentication data is used to authenticate the data. | 02-14-2013 |
20130191632 | SYSTEM AND METHOD FOR SECURING PRIVATE KEYS ISSUED FROM DISTRIBUTED PRIVATE KEY GENERATOR (D-PKG) NODES - A system and method where the “dealer” of a split Master Secret becomes the Master Key Server, whose role is to initially compute the Master Secret, create and distribute shares of the Master Secret to two Distributed Private Key Generators (D-PKG), initialize and route the inter-process communication between the nodes, co-ordinate and computationally participate in the User System's IBE Private Key generation process. | 07-25-2013 |
20130191638 | SYSTEM AND METHOD FOR SECURE TWO-FACTOR AUTHENTICATED ID-BASED KEY EXCHANGE AND REMOTE LOGIN USING AN INSECURE TOKEN AND SIMPLE SECOND-FACTOR SUCH AS A PIN NUMBER - A system and method of authenticated ID-based key exchange and remote login with insecure token and PIN number can provide an authenticated key agreement protocol based on an elliptic curve bilinear type-3 pairing. A server acts as an Authentication Service to Clients and a Trusted Authority (TA) issues identity based secret numbers to Clients and Authentication Services. Included in the system and method is the capability for the Client to split their secret number into two parts, a Client selected PIN number, and the larger number, the Token. | 07-25-2013 |
David Spector, San Francisco, CA US
Patent application number | Description | Published |
---|---|---|
20140270540 | DETERMINING DIMENSION OF TARGET OBJECT IN AN IMAGE USING REFERENCE OBJECT - Systems and methods for determining one or more dimensions of an object using a digital image are described. | 09-18-2014 |
David L. Spector, Cold Spring Harbor, NY US
Patent application number | Description | Published |
---|---|---|
20100075365 | PERINUCLEOLAR COMPARTMENT AS A CANCER MARKER - The present invention relates to compositions and methods for cancer diagnostics, prognostics and predictions, including but not limited to, cancer markers. In particular, the present invention provides perinucleolar compartments and their resident molecules as cancer markers. | 03-25-2010 |
20120309017 | PERINUCLEOLAR COMPARTMENT AS A CANCER MARKER - The present invention relates to compositions and methods for cancer diagnostics, prognostics and predictions, including but not limited to, cancer markers. In particular, the present invention provides perinucleolar compartments and their resident molecules as cancer markers. | 12-06-2012 |
Deborah H. Spector, La Jolla, CA US
Patent application number | Description | Published |
---|---|---|
20100272752 | VACCINE FOR VIRUSES THAT CAUSE PERSISTENT OR LATENT INFECTIONS - The invention is in general directed to methods and compositions for preventing or treating infections by viruses involved in persistent and/or latent infections. The methods and compositions are directed toward the prevention and treatment of infections caused by viruses such as, for example, herpesviruses, retroviruses, hepatitis viruses, and papillomaviruses, including, for example, cytomegalovirus. | 10-28-2010 |
20140193460 | HERPES VIRUS VACCINE AND METHODS OF USE - Provided herein are, inter alia, vaccines and methods of using the same for the treatment or prevention of Herpesvirus infections. | 07-10-2014 |
20160067330 | HERPES VIRUS VACCINES AND TREATMENTS - Provided herein are vaccine compositions and methods of their use in treating or preventing Herpes diseases. | 03-10-2016 |
Donald Spector, Union City, NJ US
Jason Spector, New York, NY US
Patent application number | Description | Published |
---|---|---|
20110212049 | POLYMER COMPOSITIONS OF DIHYDROXYACETONE AND USES THEREOF - The present disclosure provides injectable synthetic and biodegradable polymeric biomaterials that effectively prevent seroma, a common postoperative complication following ablative and reconstructive surgeries. Provided biomaterials include physically crosslinked hydrogels that are thixotropic, display rapid chain relaxation, are easily extruded through narrow gauge needles, biodegrade into inert products, are well tolerated by soft tissues, and effectively prevent seroma in a radical breast mastectomy animal model. | 09-01-2011 |
20150079019 | POLYMER COMPOSITIONS OF DIHYDROXYACETONE AND USES THEREOF - The present disclosure provides injectable synthetic and biodegradable polymeric biomaterials that effectively prevent seroma, a common postoperative complication following ablative and reconstructive surgeries. Provided biomaterials include physically crosslinked hydrogels that are thixotropic, display rapid chain relaxation, are easily extruded through narrow gauge needles, biodegrade into inert products, are well tolerated by soft tissues, and effectively prevent seroma in a radical breast mastectomy animal model. | 03-19-2015 |
Jason A. Spector, New York, NY US
Patent application number | Description | Published |
---|---|---|
20110270412 | FABRICATION OF A VASCULAR SYSTEM USING SACRIFICIAL STRUCTURES - The first aspect of the present invention is directed to a method of producing a vascular network preform (VNP). This method involves forming a network of elongate fibers and at least one elongate structure from a sacrificial material. The diameter of the elongate structure is greater than that of the elongate fibers. The network of elongate fibers is placed in contact with at least one elongate structure either following or during forming the network of elongate fibers or forming the at least one elongate structure. A matrix is applied around the network of elongate fibers, in contact with the at least one elongate structure. The network of elongate fibers and elongate structure, within the matrix is sacrificed to form a preform. The resulting preform contains a vascular network of fine diameter tubes in contact with at least one elongate passage having a diameter greater than that of the fine diameter tubes. The resulting solid preform and methods of using it are also disclosed. | 11-03-2011 |
Lawrence C. Spector, Austin, TX US
Patent application number | Description | Published |
---|---|---|
20100186741 | Method and System for Detecting Mouth Leak During Application of Positive Airway Pressure - A method and system for providing therapeutic gas to a patient during positive airway pressure ventilation and, more particularly, detecting the presence of a mouth leak during ventilation and, upon the detection of a mouth leak, reducing the applied pressure so as to reduce irritation and discomfort experienced by the patient. Respiratory air flow from a patient is measured in a waveform as a function of time. An approximate value of the root mean square voltage of the waveform is established during a period in which the patient is experiencing a mouth leak and a root mean square voltage of the waveform is established during a period in which the patient is experiencing an apneic event. The waveform is subsequently monitored and the rate of respiratory airflow is decreased when there is an indication of a mouth leak provided there is no indication of an apneic event. | 07-29-2010 |
Lisa Spector, New York, NY US
Patent application number | Description | Published |
---|---|---|
20130305555 | BABA BUDDY BABY BOTTLE DRYING WAND - The invention provides a bottle drying wand comprising a handheld wand tool including a disposable or reusable drying cloth and configured to easily dry infant and toddler baby bottles and sippy cups. The Baba Buddy comprises a drying wand tool wherein the base of the drying wand tool is a contoured and rounded handle to facilitate a comfortable grip. The distal end of the Baba Buddy culminates in a trident configuration having two elongated and tapered fork like tines positioned side by side. Centrally positioned between these rounded tines is a slightly shorter designed to attach and secure the drying cloth to the tool. | 11-21-2013 |
Michael S. Spector, Washington, DC US
Patent application number | Description | Published |
---|---|---|
20100262529 | Arbitrage of Tracking Securities - A financial product is based on a first fund that is traded on a trading marketplace in a first country. The financial product is registered in the first country. The first fund has the characteristics of being based on an index of securities that are traded in a second, different country. The first fund is arbitragable with a second fund that is based on the index and which is registered in a second different country. The first fund has a creation unit basis that is substantially the same basis as a creation unit basis for the second fund. The calculation of the net asset value of the first fund occurs at essentially or exactly the same time that second country fund has its NAV calculated. | 10-14-2010 |
20110022511 | Balancing Arbitragable Tracking Securities - A financial product is based on a first fund that is traded on a trading marketplace in a first country. The financial product is registered in the first country. The first fund has the characteristics of being based on an index of securities that are traded in a second, different country. The first fund is arbitragable with a second fund that is based on the index and which is registered in a second different country. The first fund has a creation unit basis that is substantially the same basis as a creation unit basis for the second fund. The calculation of the net asset value of the first fund occurs at essentially or exactly the same time that second country fund has its NAV calculated. The agent for the first fund has the option of providing or accepting second fund shares or other securities, rather than cash, to cover “cash amount” obligations. Such obligations arise from the need to equate the value received or given for the first fund shares (e.g., the creation unit stock basket plus or minus the “cash amount”) with the NAV of the first fund shares that it has issued or received. | 01-27-2011 |
Mona S. Spector, Cold Spring Harbor, NY US
Patent application number | Description | Published |
---|---|---|
20090029872 | Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof - This invention provides a genetically tractable in situ non-human animal model for hepatocellular carcinoma. The model is useful, inter alia, in understanding the molecular mechanisms of liver cancer, in understanding the genetic alterations that lead to chemoresistance or poor prognosis, and in identifying and evaluating new therapies against hepatocellular carcinomas. The liver cancer model of this invention is made by altering hepatocytes to increase oncogene expression, to reduce tumor suppressor gene expression or both and by transplanting the resulting hepatocytes into a recipient non-human animal. | 01-29-2009 |
20110035814 | COOPERATING ONCOGENES IN CANCER - This invention provides methods of diagnosis, drug screening, and treatment based on the discovery that cIAP1 and Yap are co-amplified oncogenes that cooperate to contribute to oncogenesis and tumor maintenance. | 02-10-2011 |
Myron Spector, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20140094806 | SURGICAL INSTRUMENT FOR PENETRATING REMOVING BONE - A surgical instrument whose cutting portion is a sharp miniature chisel or awl shape with a series of ridges along the course of the cutting tool. Each ridge has, on its proximal surface, a concave surface. Upon retraction, the instrument is pushed against the side of the defect, allowing the compacted bone on the walls to be captured in the concave recesses of the instrument. Existing instruments compact bone against the walls of the surgical defect rather than removing the compacted bone or tissue. The creation of a small surgically created wound in subchondral bone, absent the thickened compacted bone at the margins, responds with rapid vascular penetration and cellular migration and faster healing with an enhanced histologically confirmed maturing tissue. The surgical defect can be round or slit-like. The instrument allows a wide spectrum of angle of attack to create the surgical defect in the bone and/or articular surface. | 04-03-2014 |
20140094809 | METHOD OF REDUCING SIDEWALL COMPACTION IN A BONE OR ARTICULAR JOINT PENETRATION - A method of creating a penetration with reduced sidewall compaction in a surface of a bone or articular joint. The method includes the steps of positioning a surgical instrument in contact with the surface, applying a longitudinal force to the surgical instrument causing the surgical instrument to penetrate the surface thereby creating a penetration with at least one sidewall, and retracting the surgical instrument and strategically scraping a portion of the surgical instrument against a portion of the at least one sidewall to remove compacted material from the penetration, thereby creating a small surgically created wound in the surface having reduced compaction at the margins to promote rapid vascular penetration, cellular migration, and faster healing with an enhanced histologically confirmed maturing tissue. The surgical defect can be round or slit-like. | 04-03-2014 |
Myron Spector, Brookline, MA US
Patent application number | Description | Published |
---|---|---|
20090186062 | Method of Repairing Meniscal Tears - A method of repairing a meniscal tear of a subject includes providing a sheet of collagen membrane material having on one side thereof a smooth barrier face which inhibits cell adhesion thereon and inhibits passage of cells therethrough. The sheet has a fibrous face opposite the smooth barrier face, the fibrous face allowing cell growth thereon. The collagen is predominantly collagen I. The sheet of collagen membrane material is fixed over a meniscal tear so that the fibrous face is oriented toward the meniscal tear. | 07-23-2009 |
20100291173 | METHOD OF IMPROVING RENAL FUNCTION - A method of improving renal function in a mammal suffering from, or at risk of developing, at least partial renal failure or renal dysfunction, includes administering to renal tissue of the mammal, a combination comprising a non-viral vector comprising a non-viral particulate carrier which carries a therapeutically effective amount of genetic material capable of expressing a renal function-enhancing Osteogenic Protein-1/Bone Morphogenic Protein-7 (OP-1/BMP-7) polypeptide in the renal tissue. | 11-18-2010 |
Neil Spector, Durham, NC US
Patent application number | Description | Published |
---|---|---|
20140336202 | METHODS OF IDENTIFYING AND USING MDM2 INHIBITORS - Methods of treating subjects with cancer and screening for MDM2 inhibitors that may be effective cancer therapeutics are provided herein. The cancers that may be treated using MDM2 inhibitors using the methods described herein include those that are or may become resistant to treatment with tyrosine kinase inhibitors. Methods of treating subjects with cancers that have, or develop in response to treatment with tyrosine kinase inhibitors, elevated levels of MDM2, Mcl-1 or PP5 or decreased levels of Huwe1 or CAS using MDM2 inhibitors are provided herein. The MDM2 inhibitors may be effective at treating these cancers alone or in combination with a tyrosine kinase inhibitor regardless of p53 status (mutant or wild-type) of the cancer. | 11-13-2014 |
Neil Spector, Chapel Hill, NC US
Patent application number | Description | Published |
---|---|---|
20100249160 | Cancer Treatment Method - A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolineamines. | 09-30-2010 |
20110312982 | Cancer Treatment Method - A method of treating cancer is described including administration of a 4-quinazolinamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolinamines. | 12-22-2011 |
20120058113 | CANCER TREATMENT METHOD - A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolineamines. | 03-08-2012 |
20150366868 | CANCER TREATMENT METHOD - A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolineamines. | 12-24-2015 |
Neil L. Spector, Durham, NC US
Patent application number | Description | Published |
---|---|---|
20100063074 | Cancer Treatment Method - The present invention relates to a method of treating cancer in a mammal by administration of 4-quinazolinamines and pharmaceutical compositions containing the same. In particular, the method relates to a methods of treating cancers which are mediated by the tyrosine kinases EGFR and/or erbB2 by administration of N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine and salts and solvates thereof. | 03-11-2010 |
20150202294 | USE OF PSORALEN DERIVATIVES AND COMBINATION THERAPY FOR TREATMENT OF CELL PROLIFERATION DISORDERS - Methods for the treatment of a cell proliferation disease or disorder in a subject, involving applying a psoralen derivative lacking a DNA cross-linking motif to cancer cells, applying a psoralen or a derivative thereof and lapatinib, or applying a psoralen or derivative thereof and neratinib, to a subject and further applying initiation radiation energy form an energy source. | 07-23-2015 |
Neil Lee Spector, Research Triangle Park, NC US
Patent application number | Description | Published |
---|---|---|
20150190397 | Treatment of Cancers Expressing p95 ErbB2 - The truncated ErbB2 receptor (p95ErbB2) is shown to differ from the full-length ErbB2 receptor in its association with other ErbB receptors. The truncated receptor preferentially associated with ErbB3, whereas full length ErbB2 heterodimerizes with 5 either EGFR or ErbB3. Consistent with p95ErbB2 heterodimerization with ErbB3, it is shown that heregulin (an ErbB3 ligand) stimulates p95ErbB2 phosphorylation in breast cancer cell lines. Described herein are methods of identifying patients suitable for treatment with a p95ErbB2 inhibitor, and methods of treating such patients. | 07-09-2015 |
Neil Lee Spector, Durham, NC US
Patent application number | Description | Published |
---|---|---|
20090192189 | TREATMENT OF CANCERS EXPRESSING P95 ERBB2 - The truncated ErbB2 receptor (p95 | 07-30-2009 |
20110020335 | Treatment of Cancers Expressing p95 ErbB2 - The truncated ErbB2 receptor (p95 | 01-27-2011 |
Pamela R. Spector, New York, NY US
Patent application number | Description | Published |
---|---|---|
20140128144 | IN-VEHICLE GAMING SYSTEM FOR PASSENGERS - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140128145 | IN-VEHICLE GAMING SYSTEM FOR A DRIVER - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140128146 | CUSTOMIZABLE IN-VEHICLE GAMING SYSTEM - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 05-08-2014 |
20140256426 | IN-VEHICLE GAMING SYSTEM - An in-vehicle gaming system may be played by a driver alone, or simultaneously or individually by a driver and/or one or more other users. The in-vehicle gaming system may be activated or controlled by, for example, touch, voice, or gesture. Gameplay is dynamically adjusted based at least in part on environmental factors such that the driver is not distracted from driving the vehicle. Game content is generated based at least in part on environmental factors and user data. | 09-11-2014 |
Peter Spector, Burlington, VT US
Patent application number | Description | Published |
---|---|---|
20090287089 | Methods, devices and apparatus for imaging for reconstructing a 3-D image of an area of interest - Featured are methods, devices and apparatuses for imaging tissue, such as cardiac tissue, using any of a number of imaging techniques (e.g., ultrasonic imaging techniques) and a 3-D tracking system. In embodiments, such methods, devices and apparatuses are configured so that a 3-D image can be reconstructed from image data acquired at different locations from the image data and three dimensional coordinates that are determined for each location whereat the imaging device was located. | 11-19-2009 |
Peter S. Spector, Burlington, VT US
Patent application number | Description | Published |
---|---|---|
20140200429 | METHODS AND SYSTEMS FOR MAPPING CARDIAC FIBRILLATION - Methods and systems for mapping cardiac fibrillation in a patient include deploying a catheter in the patient's heart, wherein the catheter includes an array of at least one stacked electrode pair having a first electrode and a second electrode. Each electrode pair is configured to be orthogonal to the surface of a cardiac tissue substrate. A plurality of measurements are obtained from the electrode array in response to electrical activity in the cardiac tissue substrate for a duration indicative of a number of electrical circuit cores and distribution of the electrical circuit cores across the cardiac tissue substrate in the patient's heart. These are processed to obtain the density and distribution of electrical circuit cores which are mapped onto a representation of the patient's heart. | 07-17-2014 |
20140200430 | CATHETER SYSTEMS AND RELATED METHODS FOR MAPPING, MINIMIZING, AND TREATING CARDIAC FIBRILLATION - Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each electrode pair including a first electrode and a second electrode, wherein each electrode pair is configured to be orthogonal to a surface of a cardiac tissue substrate, wherein each first electrode is in contact with the surface to record a first signal, and wherein each second electrode is separated from the first electrode by a distance which enables the second electrode to record a second signal, wherein the catheter is configured to obtain one or more measurements from at least a first signal and a second signal in response to electrical activity in the cardiac tissue substrate indicative of a number of electrical circuit cores and distribution of the electrical circuit cores for a duration across the cardiac tissue substrate. | 07-17-2014 |
20140200471 | METHODS AND SYSTEMS FOR DETERMINING SPATIOTEMPORAL VARIABILITY FOR MAPPING CARDIAC FIBRILLATION - Methods and systems for determining optimal spatial resolution for mapping cardiac fibrillation in a patient, including obtaining one or more electrograms, having an initial spatial resolution; calculating at least one electrogram frequency; obtaining one or more electrograms, having a higher spatial resolution; calculating at least one electrogram frequency, having a higher spatial resolution; comparing at least one electrogram frequency having a higher spatial resolution with at least one electrogram frequency having an initial spatial resolution; iterating the steps above until the electrogram frequencies of the two compared electrograms are the same; and identifying at least one of minimum spatial resolution threshold and an optimal spatial resolution based on the step of comparing. | 07-17-2014 |
20140200571 | METHODS AND SYSTEMS FOR ASSESSING CARDIAC FIBRILLOGENICITY - Methods and systems for assessing cardiac fibrillogenicity in a patient includes generating a map of a duration of one or more measurements indicative of a number of electrical circuit cores and distribution of the electrical circuit cores across a cardiac tissue substrate in the patient's heart in response to electrical activity in the cardiac tissue substrate, the map being registered onto a representation of the patient's heart, applying a set of executable instructions to the map to define an optimal placement of at least one ablation lesion in the cardiac tissue substrate, and calculating total length of the at least one ablation lesion, wherein the total length measure is indicative of the patient's cardiac fibrillogenicity to inform treatment using catheter ablation. | 07-17-2014 |
20140200572 | METHODS AND SYSTEMS FOR MINIMIZING AND TREATING CARDIAC FIBRILLATION - Methods and systems for using feedback to minimize and treat cardiac fibrillation in a patient, includes generating a map of one or more measurements indicative of a number and distribution of electrical circuit cores for a duration across a cardiac tissue substrate in the patient's heart in response to electrical activity, defining an optimal placement of at least one ablation lesion in the cardiac tissue substrate; applying ablation lesion therapy based on the optimal placement; determining whether the ablation lesion therapy minimized or treated cardiac fibrillation; if therapy is determined to have minimized or treated cardiac fibrillation, assessing fibrillogenicity of the cardiac tissue substrate to determine whether fibrillogenicity is below a predetermined threshold; and if therapy is determined to have not minimized or treated cardiac fibrillation, repeating the steps of generating, defining, applying, and determining until ablation lesion therapy minimizes or treats cardiac fibrillation. | 07-17-2014 |
20140200575 | METHODS AND SYSTEMS FOR OPTIMIZING LESION PLACEMENT TO MINIMIZE AND TREAT CARDIAC FIBRILLATION - Methods and systems for optimizing lesion placement to treat cardiac fibrillation in a patient include obtaining a map of one or more measurements indicative of a number and distribution of electrical circuit cores for a duration across a cardiac tissue substrate in response to electrical activity in the cardiac tissue substrate, identifying at least one region for the duration of the cardiac tissue substrate having a number of electrical circuit cores that is higher than a predetermined density threshold, generating a first sample set of lesions, the first sample set of lesions being registered onto the map, calculating and comparing a first total length of the first sample set of lesions to a predetermined length threshold, determining fitness of the first sample set of lesions, wherein fitness criteria is indicative of the level to which the sample set can terminate or at least minimize cardiac fibrillation. | 07-17-2014 |
Peter Salem Spector, Colchester, VT US
Patent application number | Description | Published |
---|---|---|
20140278324 | Interactive Tissue Model for Simulating the Electrical Activity of Excitable Tissues - A method of simulating electrical propagation in the heart muscle on a computing device having a processor and a memory includes providing a structural representation of a heart muscle. The structural representation includes a plurality of tissue elements. The plurality of tissue elements have a shape corresponding to shape of a heart muscle. The method includes storing a model of electric potential propagation through the structural representation in the memory. The model includes a piecewise linear equation describing electrical activity within each tissue element and a difference equation describing conduction from one of the tissue elements to an adjacent tissue element. The method also includes providing a first set of tunable parameters for inclusion in the piecewise linear equation and a second tunable parameter for inclusion in the difference equation. The method further includes tuning the first set of tunable parameters and the second tunable parameter in the model. The method also includes running said model on the processor of the computing device and displaying the simulated electrical propagation through the heart muscle over time. | 09-18-2014 |
Samuel Spector, Edison, NJ US
Patent application number | Description | Published |
---|---|---|
20090204048 | Easy removable bandage - Self adhering type of a bandage having a tab or tabs without adhesive coatings, to facilitate easy removal from a wound. As an alternate for easy removal, self adhering bandage having areas at the inner surface edges without adhesive coatings and distinguishing markings and/or colors on the opposite outer uncoated side to locate the uncoated areas. | 08-13-2009 |
20130081832 | CRACK AND CREVICE WEEDER TOOL - A tool for removing undesired growth between adjacent surfaces includes a pair of flanges of generally equal width and length symmetrically located about a central axis and having a front end and a back end. The flanges are shaped to form a generally curved V-shaped opening at their front end whose width decreases gradually in a curved manner to form a narrow region terminating at an end point along the central axis. The flanges Kaye inner facing surfaces which are disposed with respect to each other to define an interior angle which may vary over a wide range. A handle is attached via a bracket to the flanges for enabling the front end of the flanges to be urged under undesirable growth, and wedging the undesirable growth within the narrow region for enabling the removal of the undesirable growth with its roots. | 04-04-2013 |
Scott L. Spector, Washington, DC US
Patent application number | Description | Published |
---|---|---|
20130061138 | METHOD AND SYSTEM FOR CREATING A STEP-BY-STEP INSTRUCTION GUIDE - A step-by-step electronic instruction guide is created for users to learn, operate, and perform a wide variety of tasks. The step-by-step instructions are created, edited, published, and shared using an interactive template and intuitive user interface to provide explanations and information of interest. Users integrate images, text, and audio and visual materials to create discrete steps of an instruction manual. The individual steps are created and stored on a computing device and database, where they can be edited, assembled, distributed, and communicated to other users. The computing device includes storage devices, display devices, and processors that create, store, retrieve, and display step-by-step instructions. The computing device includes editing and control modules that access, manipulate, and present the step-by-step instructions and a graphics module that receives the instructions from the database and processor and outputs a visual and/or audio depiction of the step-by-step instructions. | 03-07-2013 |
Shari Spector, Lexington, MA US
Patent application number | Description | Published |
---|---|---|
20100063256 | Novel immunoglobulin-binding proteins with improved specificity - The present invention relates to modified immunoglobulin-binding proteins, e.g., | 03-11-2010 |
20100221844 | Caustic stable chromatography ligands - The present invention relates to chromatography ligands having improved caustic stability, e.g., ligands based on immunoglobulin-binding proteins such as, | 09-02-2010 |
20130046056 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 02-21-2013 |
20140046037 | NOVEL IMMUNOGLOBULIN-BINDING PROTEINS WITH IMPROVED SPECIFICITY - The present invention relates to modified immunoglobulin-binding proteins, e.g., | 02-13-2014 |
20140296434 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 10-02-2014 |
20150080558 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 03-19-2015 |
20150252085 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 09-10-2015 |
Shelly J. Spector, Short Hills, NJ US
Patent application number | Description | Published |
---|---|---|
20110256842 | APPARATUS AND METHOD FOR BROADCASTING MESSAGES TO SELECTED GROUP(S) OF USERS - There is disclosed a method and apparatus for transmitting a message to at least one group of users selected from a population of the users. The method comprises the steps of assigning to each member of the one group a common characteristic or indication, collecting from each member of the population an address to which the message may be sent, selecting the common characteristic of a group of message recipients and determining therefrom the users of a particular group or groups based upon the selected common characteristic, whereby messages may be quickly and efficiently sent to all of the users of the selected group(s). | 10-20-2011 |
Steven J. Spector, Lexington, MA US
Patent application number | Description | Published |
---|---|---|
20120236389 | ON-CHIP MINIATURE OPTICAL ISOLATOR - An optical structure for generating nonreciprocal loss is provided that includes a first substrate layer and a magneto-optical layer positioned on the first substrate layer. The magneto-optical layer achieves nonreciprocity with application of an external magnetic field so as to produce resonantly enhanced nonreciprocal loss. | 09-20-2012 |
Steven J. Spector, Arlington, MA US
Patent application number | Description | Published |
---|---|---|
20100025787 | System and method for providing a high frequency response silicon photodetector - A Silicon photodetector contains an insulating substrate having a top surface and a bottom surface. A Silicon layer is located on the top surface of the insulating substrate, where the Silicon layer contains a center region, the center region being larger in thickness than the rest of the Silicon layer. A top Silicon dioxide layer is located on a top surface of the center region. A left wing of the center region and a right wing of the center region are doped. The Silicon photodetector also has an active region located within the center region, where the active region contains a tailored crystal defect-impurity combination and Oxygen atoms. | 02-04-2010 |
Steven Jay Spector, Lexington, MA US
Patent application number | Description | Published |
---|---|---|
20110170825 | Waveguide Coupler Having Continuous Three-Dimensional Tapering - A solid state waveguide coupler is provided including a first coupler end disposed on a solid state material substrate for connection to a first solid state waveguide located on the substrate and a second coupler end disposed on the substrate for connection to a second waveguide located on the substrate. A coupling span, comprising a waveguide material layer on the substrate, is disposed between the first and second coupler ends and tapers between a height of the first waveguide and a height of the second waveguide, tapers between a width of the first waveguide and a width of the second waveguide, and includes curved sidewalls along at least a portion of the tapered coupling span. In a method for fabricating the waveguide coupler, material is isotropically removed from a waveguide material layer on the substrate to produce tapered surfaces between the first waveguide and the second waveguide. | 07-14-2011 |
Thomas Spector, Durham, NC US
Patent application number | Description | Published |
---|---|---|
20110130359 | METHODS FOR PREVENTING OR REDUCING NEUROTOXICITY ASSOCIATED WITH ADMINISTERING DPD INHIBITORS IN COMBINATION WITH 5-FU AND 5-FU PRODRUGS - Methods for improved administration and dosing of DPD inhibitors in combination with 5-FU and/or 5-FU prodrugs are provided, comprising first administering to a patient in need thereof a DPD inhibitor that substantially eliminates activity of the enzyme in both nervous and non-nervous tissues within the patient and thereafter administering 5-FU or a 5-FU prodrug, wherein the level of 5-FU or 5-FU generated from a prodrug is in substantial excess of DPD inhibitor in the patient. | 06-02-2011 |
20130184232 | METHODS FOR ADMINISTERING DPD INHIBITORS IN COMBINATION WITH 5-FU AND 5-FU PRODRUGS - Methods for improved administration and dosing of DPD inhibitors in combination with 5-FU and/or 5-FU prodrugs are provided, comprising first administering to a patient in need thereof a DPD inhibitor that substantially eliminates activity of the enzyme and thereafter administering 5-FU or a 5-FU prodrug, wherein the level of 5-FU or 5-FU prodrug is in substantial excess of DPD inhibitor in the patient. | 07-18-2013 |
Yuval Spector, Palo Alto, CA US
Patent application number | Description | Published |
---|---|---|
20100115519 | METHOD AND SYSTEM FOR SCHEDULING IMAGE ACQUISITION EVENTS BASED ON DYNAMIC PROGRAMMING - A method and system for scheduling events into a set of opportunities is presented. The method includes 1) dividing a path of an image acquisition device so that there is at least a first portion and a second portion at any given moment, wherein each of the first portion and the second portion includes at least one state and the first portion includes a null state in which no image is taken; 2) combining each state in the first portion with at least one state in the second portion one by one to generate a series of updated sequences; and 3) selecting at least one of the updated sequences based on a merit value associated with each of the updated sequences. The invention uses only two groups out of all the relevant opportunities for most calculations, and is especially applicable to situations like satellite pass scheduling. | 05-06-2010 |