Mcgettrick
Aileen Mcgettrick, Herne Bay GB
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20150064711 | ASSAY LABEL - This invention relates to an assay label comprising an amorphous carbon particle, a functionalised dextran polymer attached to the surface of the carbon particle and a first member of a complementary binding pair covalently bonded to the functionalised dextran polymer. The invention also provides a device incorporating the assay label, which further comprises a radiation source adapted to generate a series of pulses of electromagnetic radiation at a wavelength such that the absorption of the radiation by the label generates energy by non-radiative decay; a sample chamber containing a transducer having a pyroelectric or piezoelectric element and electrodes which is capable of transducing energy generated by non-radiative decay into an electrical signal; and a detector which is capable of detecting the electrical signal generated by the transducer. | 03-05-2015 |
Anne Mcgettrick, Dublin IE
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20090123482 | ASSAYS FOR DETERMINING COMPOUNDS WHICH MODULATE TRAM PHOSPHORYLATION - Disclosed are assays for the determination and quantification of the phosphorylation of TRAM (Trif-related adaptor molecule). TRAM is rapidly phosphorylated upon LPS stimulation by protein kinase C epsilon (PKCε) and that this phosphorylation is vital for TRAM to function normally. Assays suitable for detecting the state of phosphorylation of TRAM have utility in identifying compounds which have activity in modulating TRAM. Further disclosed are compounds which have utility in modulating the phosphorylation of TRAM to modulate signalling mediating by the Toll Like Receptor 4 (TLR4) receptor. | 05-14-2009 |
Helen Mcgettrick, Birmingham GB
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20150051137 | PEPTIDE AND USES THEREFOR - Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N′-SVTEQGAELSNEER-C′ {SEQ ID NO: 1) or an analogue thereof that inhibits T cell migration. Also provided is the peptide or its analogue for use in the methods of treatment: and/or prophylaxis of said condition. | 02-19-2015 |
James Mcgettrick, Chester GB
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20110177255 | METHOD FOR PRODUCING AN ALDEHYDE CONTAINING COATING - A method is provided for applying a reactive aldehyde containing coating to a substrate. The method includes subjecting a substrate to a plasma discharge in the presence of a compound of formula (I): | 07-21-2011 |
James Mcgettrick, County Durham GB
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20100055413 | ARTICLE, AND A METHOD FOR CREATING THE ARTICLE, WITH A CHEMICALLY PATTERNED SURFACE - The invention relates to the provision of an article and a method of forming an article with a surface which can have at least one sub-layer and a top layer of material. At least one part of the top layer is selectively removed to expose at least one sub-layer and/or the surface of the substrate and allow the functionality of the sub-layer and/or surface to be utilised in the area(s) where it is exposed. The top layer, where it remains, acts as a barrier to the sub-layer and/or surface being exposed to the surrounding environment. Typically parts of the top layer are removed in a patterned manner to provide a series of predefined areas at which the sub-layer or sub-layers are selectively exposed. | 03-04-2010 |
James Douglas Mcgettrick, West Glamorgan GB
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20150325719 | AN OPTO-ELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE SAME - The present invention relates to an opto-electronic device comprising: (a) a first component ( | 11-12-2015 |
Ronald J. Mcgettrick, Sheboygan, WI US
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20120074032 | FOOD PAN HAVING CORNER STRUCTURE - A food pan is configured for use with a serving station having wells within which to support the food pan. The food pan includes a bottom, a side wall, a rim, and four corner structures. The bottom has a substantially rectangular periphery. The side wall is connected to the bottom, and projects from the rectangular periphery of the bottom in an upward direction. Together, the bottom and side wall form a volume configured to support contents of the food pan. The rim is connected to the side wall on an end of the side wall opposite to the bottom, and extends from the side wall in an outward direction away from the volume formed by the side wall and the bottom. The cross-section of the rim further includes an ascending portion connected to the side wall, a top portion connected to the ascending portion, and a descending portion connected to the top portion. The ascending and descending portions are rounded. The four corner structures are located between the side wall and the rim, with each corner structure associated with one of the corners of the rectangular periphery of the bottom of the food pan. Each corner structure further includes a base side connected to the side wall and two ascending sides connected to the base side. The two ascending sides extend along both the side wall and the ascending portion of the cross-section of the rim. Additionally, the ascending sides extend from opposite ends of the base side and terminate in the top portion of the cross-section of the rim. | 03-29-2012 |