Patent application number | Description | Published |
20100002228 | Method and Apparatus for Conducting Raman Spectroscopy - Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber. | 01-07-2010 |
20100290042 | Use of Free-space Coupling Between Laser Assembly, Optical Probe Head Assembly, Spectrometer Assembly and/or Other Optical Elements for Portable Optical Applications Such as Raman Instruments - An apparatus includes: a handheld Raman analyzer that can include: a common platform; a laser assembly mounted on a laser platform, the laser platform supported on the common platform by a first material and a second thermally conductive material wherein the first material is softer than the second material; an optical probe head assembly disposed on the common platform, the optical probe head assembly spaced apart from the laser assembly; a spectrometer assembly disposed on the common platform, the spectrometer assembly spaced apart from the optical probe head assembly; and an analysis apparatus configured to identify a specimen based on a Raman signature received from the spectrometer. The laser assembly can be optically coupled to the optical probe head assembly by at least a first free-space coupling region and the optical probe head assembly optically coupled to the spectrometer assembly by at least a second free-space coupling region. | 11-18-2010 |
20130016337 | HEROIN DETECTION BY RAMAN SPECTROSCOPY FROM IMPURE COMPOSITIONS COMPRISING AN INTERFERING FLUORESCENT CONTAMINANT - A method of identifying the presence of heroin in an impure heroin composition which contains heroin and at least one fluorescent contaminant which interferes with a Raman signal from the heroin. The method may include contacting the mixture with a solvent such as an alcohol, then contacting the resulting alcohol composition with a SERS surface. The surface may then be exposed to laser light from a hand-held Raman spectrometer to detect a Raman signal from the heroin. An apparatus for performing the method is also provided. | 01-17-2013 |
Patent application number | Description | Published |
20100055168 | CATIONIC LIPIDS AND USES THEREOF - Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed. | 03-04-2010 |
20100055169 | CATIONIC LIPIDS AND USES THEREOF - Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed. | 03-04-2010 |
20100063135 | POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF - Polyethylene glycol (PEG)-lipid conjugates, polyethylene glycol (PEG)-lipid conjugate based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed. | 03-11-2010 |
20100104629 | CATIONIC LIPIDS AND USES THEREOF - Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed. | 04-29-2010 |
20100115635 | Methods for Assessing the Delivery of Exogenous Agents - This invention provides methods, compositions and kits for rapid determination of the delivery of exogenous agents both in vitro and in vivo, including without limitation siRNA, microRNA, a ribozyme or an antisense molecule, any of which may target, bind to, or inactivate the mRNA of the gene of interest expressed in the cells. The methods, compositions and kits utilize a promoter-reporter construct whereby successful non-viral nucleic acid delivery leads to an up-regulation of reporter signals thus providing a quantitative, sensitive and rapid means of detection, validation and monitoring. | 05-06-2010 |
20100227838 | Combination Therapy for Treating Cancer and Diagnostic Assays for Use Therein - The present disclosure relates to a combination of therapeutic agents for use in treating a patient a subject suffering from cancer. In addition, the present disclosure also relates to diagnostic assays useful in classification of patients for treatment with one or more therapeutic agents. | 09-09-2010 |
20100251392 | METHODS FOR ASSESSING THE DELIVERY OF EXOGENOUS AGENTS - This invention provides methods, compositions and kits for rapid determination of the delivery of exogenous agents both in vitro and in vivo, including without limitation siRNA, microRNA, a ribozyme or an antisence molecule, any of which may target, bind to, or inactivate the mRNA of the gene of interest expressed in the cells. The methods, compositions and kits utilize a promoter-reporter construct whereby successful non-viral nucleic acid delivery leads to an up-regulation of reporter signals thus providing a quantitative, sensitive and rapid means of detection, validation and monitoring. | 09-30-2010 |