Patent application number | Description | Published |
20110094600 | SERIAL SIPHON VALVES FOR FLUIDIC OR MICROFLUIDIC DEVICES - Methods and devices using a co-radial arrangement of serial siphon structures composed of siphon valves each separated by a capillary valve to save radial space in a fluidic system. Such serial siphon valves allow to sequentially distribute liquids in a fluidic system upon application of successive centripetal accelerations and decelerations applied to a rotary platform. | 04-28-2011 |
20110111987 | CENTRIFUGAL MICROFLUIDIC SYSTEM FOR NUCLEIC ACID SAMPLE PREPARATION, AMPLIFICATION, AND DETECTION - A microfluidic system for processing a sample includes a microfluidic CD in the form a rotatable disc, the disc containing a plurality of separate lysis chambers therein. A magnetic lysis blade and lysis beads are disposed in each of the lysis chambers and a plurality of stationary magnets are disposed adjacent to and separate from the microfluidic CD. The stationary magnets are configured to magnetically interact with each of the magnetic lysis blades upon rotation of the microfluidic CD. Each lysis chamber may have its own separate sample inlet port or, alternatively, the lysis chambers may be connected to one another with a single inlet port coupled to one of the lysis chambers. Downstream processing may include nucleic acid amplification using thermoelectric heating as well as detection using a nucleic acid microarray. | 05-12-2011 |
20120125071 | CARBON MOLDS FOR USE IN THE FABRICATION OF BULK METALLIC GLASS PARTS AND MOLDS - Novel molds and methods for Bulk Metallic Glass (BMG) molding using carbon templates obtained from pyrolyzed materials are provided. The method employs the Carbon MEMS (C-MEMS) technique to derive molds of different geometries and dimensions. The resultant carbon structures are stable at very high temperatures and have sufficient mechanical strength to be used as master molds for the thermoplastic forming of BMGs. | 05-24-2012 |
20120244291 | LOW VOLTAGE NEAR-FIELD ELECTROSPINNING METHOD AND DEVICE - An electrospinning method includes providing a nozzle fluidically coupled to a source of polymer ink and providing a substrate adjacent to the nozzle. A first voltage is applied to the nozzle to initiate electrospinning of the polymer ink onto the substrate, wherein the first voltage is within the range of about 400V to about 1000V. The voltage is then reduced to a second, lower voltage wherein the voltage is within the range of about 600V to about 150V. | 09-27-2012 |
20120295781 | MICROFLUIDIC DEVICE FOR WHOLE BLOOD SAMPLE PREPARATION - A CD-based device for separating plasma from whole blood includes a substrate, a sedimentation chamber disposed in the substrate, and a collection chamber disposed in the substrate and in fluidic communication with the sedimentation chamber through a siphon channel. The sedimentation chamber includes a plurality of finger-like structures disposed along a radially outward edge of the sedimentation chamber, and protruding radially inward relative to the axis of rotation of the substrate. A method for separating plasma from whole blood using the CD-based device includes introducing a blood sample into the sedimentation chamber, rotating the substrate about an axis of rotation at a first rotational speed to separate the plasma from blood cells, and rotating the substrate about the axis of rotation at a second rotational speed, which is lower than the first rotational speed, to move the plasma from the sedimentation chamber into the collection chamber. | 11-22-2012 |
20140120521 | MICROFLUIDIC DEVICE, MICROFLUIDIC SYSTEM AND METHOD FOR CONTROLLING MICROFLUIDIC TEST DEVICE - A microfluidic device, a microfluidic system and a method for controlling a microfluidic test device are provided. The microfluidic device includes a rotatable platform including a sample chamber to which a sample is supplied, a first reagent chamber; a first capture conjugate disposed in the first reagent chamber and configured to capture a target material contained in the sample; a second reagent chamber; a signal material disposed in the second reagent chamber and configured to be electrochemically induced by the first capture conjugate; a reaction chamber providing an area in which a biochemical reaction between the sample and the signal material supplied occurs when the platform rotates; a second capture material disposed in the reaction chamber and configured to capture the target material; a detection chamber separated from the reaction chamber, the detection chamber comprising a detector configured to detect an electrochemical signal generated by the signal material; and a plurality of channels connecting the chambers. | 05-01-2014 |
Patent application number | Description | Published |
20100051446 | FABRICATION OF SUSPENDED CARBON MICRO AND NANOSCALE STRUCTURES - Methods for the fabrication of suspended carbon structures using a negative photoresist that is exposed to a source of UV light, and a two step pyrolysis process. Ebeam lithography is used to define the suspended structures. The fabrication method described herein provides a novel carbon microfabrication technique, which has potential applications in carbon based electronics, sensors, batteries, microfluidics, etc. | 03-04-2010 |
20110070490 | CARBON ELECTRODES FOR ELECTROCHEMICAL APPLICATIONS - Systems and methods are provided for producing high-surface-area three-dimensional electrodes for electrochemical applications. In one embodiment, sheets of precursor material are interleaved with sheets of a sacrificial material and then bonded to a base comprising a precursor material with a precursor bonding material. The precursor sheets, base and bonding material preferably formed from the same precursor material. The bonded structure is then pyrolyzed to create a lithium intercalating structure and remove the sacrificial material. In another embodiment, a reactive-ion etching process is used to pattern 3D structures into a sheet of precursor material. The 3D structure is then converted into a lithium intercalating structure through pyrolysis. In both embodiments, the components of the structure to be heat treated preferably comprise the same lithium intercalating precursor material. As a result, micro-scale high-aspect-ratio 3D electrode features having very fine structures can be patterned and created. | 03-24-2011 |
20110203936 | POLYMER-BASED HIGH SURFACE AREA MULTI-LAYERED THREE-DIMENSIONAL STRUCTURES AND METHOD OF MAKING SAME - A method of forming three-dimensional structures includes forming a conductive layer on a substrate and patterning a resist layer over the conductive layer, the resist layer having contained therein a plurality of vias. An electrically conductive polymer is then electro-deposited in the vias. The electro-deposition operation is then stopped to form one or more of posts, posts having bulbous termini (i.e., mushrooms), or a layer atop the resist layer. The resist may be removed to yield the structure which may be further processed. For example, the structure may be pyrolyzed. In addition, biomolecules may also be adhered or otherwise affixed to the structure. | 08-25-2011 |