Patent application number | Description | Published |
20100158470 | IDENTIFICATION OF SEGMENTS WITHIN AUDIO, VIDEO, AND MULTIMEDIA ITEMS - The invention pertains to methods, systems, and apparatus for identifying segments within a media item, the media segment including at least one of audio content and video content, comprising segmenting the media item into a plurality of segments as a function of subject matter, storing data identifying each segment and its subject matter, and organizing each segment within an ontology based on its subject matter. | 06-24-2010 |
20100161580 | METHOD AND APPARATUS FOR ORGANIZING SEGMENTS OF MEDIA ASSETS AND DETERMINING RELEVANCE OF SEGMENTS TO A QUERY - The invention pertains to methods, systems, and apparatus for identifying media items relevant to a selected subject matter, the method comprising determining the subject matter of a first media item, the first media item comprising at least one of audio content and video content, determining the classification within an ontology of the subject matter of the first media item, analyzing the ontology to identify other subject matter related to the subject matter of the first media item, and performing a search for other media items relevant to the subject matter of the first media item as a function of at least the other related subject matter according to the ontology. | 06-24-2010 |
20110211812 | Program Segmentation of Linear Transmission - Content streams may be segmented to provide automatic extraction and storage of content items without intervening commercials or other unrelated content. These content items may then be stored in a database and made accessible to subscribers through, for example, an on-demand service. Automatic segmentation may include the identification of program boundaries, segmentation of a content stream based on the boundaries and the subsequent classification of the segments into content types. For example, audio and video duplication detection may be used to identify commercials since commercials tend to repeat frequently over a relatively short amount of time. A system may further identify an end of program indicator in a video stream to determine when a program ends. Accordingly, if a program ends after a scheduled end time, a recording device (e.g., the program is being recorded) may automatically extend the recording time to capture the entire program. | 09-01-2011 |
20140258284 | Method and Apparatus for Organizing Segments of Media Assets and Determining Relevance of Segments to a Query - The invention pertains to methods, systems, and apparatus for identifying media items relevant to a selected subject matter, the method comprising determining the subject matter of a first media item, the first media item comprising at least one of audio content and video content, determining the classification within an ontology of the subject matter of the first media item, analyzing the ontology to identify other subject matter related to the subject matter of the first media item, and performing a search for other media items relevant to the subject matter of the first media item as a function of at least the other related subject matter according to the ontology. | 09-11-2014 |
Patent application number | Description | Published |
20140243048 | Compact Plug-In Noise Cancellation Device - A noise cancellation device (NCD) comprises a microphone, an analog-to-digital converter, a digital-to-analog converter, a rechargeable battery, and a processor. The NCD acquires an audio input, from an external device such as a stethoscope or a cell phone, and passes the analog data into an ADC (analog-to-digital converter) for signal conversion. The digitized signals are then passed to the processor for further processing. The processor contains all the processing functions such as preprocessing (divide the input data into frames and apply shaping function to each frame), short term Fourier transform (STFT), adaptive filtering, inverse STFT, and signal synthesis. | 08-28-2014 |
20150235350 | Method for Image Denoising - A method for removing noise from a noisy image includes a few important steps. The noise level of the noisy image is first estimated based on the smooth blocks of the image. The original image is divided into many small blocks. Each of these blocks is then converted from a two dimensional matrix to vector, which is a one dimensional array. The converted vectors are next grouped and then a matrix recovery process based on a principal component analysis (PCA) has been performed in order to remove the noise, wherein the key is to determine the number of principal components to retain during the denoising process. Next, the denoised vectors are converted back to the denoised blocks, and the denoised blocks are used to reconstruct a denoised image with a better image quality. | 08-20-2015 |
Patent application number | Description | Published |
20100050715 | Magnetic coded lock mechanism - A magnetic coded lock mechanism which includes a key having a plurality of recesses and a plurality of permanent magnets properly coded around the key body, a cylindrical plug having a keyway aperture, a plurality of main apertures as passages, which contain movable key pins, a plurality of auxiliary apertures as magnetic locking passages corresponding to coded key, which contain movable magnets, a plurality of fixed magnets coded around the cylindrical plug as the way for biasing the magnets and locking pins toward the keyway, and a stationary tubular cylinder having a longitudinal aperture disposed in the center for receiving the cylindrical plug, a plurality of radial main apertures as passages for mating with the main apertures of the cylindrical plug, each passage containing a driver pin with a coil spring, and radial auxiliary apertures as passages for mating with the auxiliary apertures of the cylindrical plug, each passage containing a locking pin, whereby in a locked position, the driver pins and locking pins straddle both passages to prevent relative movement between the cylindrical plug and the tubular cylinder, and in an unlocked position, when the key is insert into the keyway, the key recesses drive the key pins in the main apertures of the cylindrical plug to a predetermined level and the movable magnets in auxiliary apertures of the cylindrical plug are repelled radially outward along the passages to a predetermined level respectively, so as to cause unlocking of the magnetic lock mechanism. | 03-04-2010 |
Patent application number | Description | Published |
20090010844 | Imaging Infection With Compounds That Bind to Thymidine Kinase - The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection. | 01-08-2009 |
20130064767 | IMAGING INFECTION WITH COMPOUNDS THAT BIND TO THYMIDINE KINASE - The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection. | 03-14-2013 |
20130323167 | DETECTING AND TREATING SOLID TUMORS THROUGH SELECTIVE DISRUPTION OF TUMOR VASCULATURE - Several agents capable of inducing vascular responses akin to those observed in inflammatory processes enhance the accumulation of nanoparticles in tumors. Exemplary vascular-active agents include a bacterium, a pro-inflammatory cytokine, and microtubule-destabilizing drugs. Such agents can increase the tumor to blood ratio of radioactivity by more than 20-fold compared to nanoparticles alone. Moreover, vascular-active agents dramatically improved the therapeutic effect of nanoparticles containing radioactive isotopes or chemotherapeutic agents. | 12-05-2013 |
20150306184 | Tumor-Specific Delivery of Therapeutic Agents via Liposomase/US - is an obligate anaerobe that can infect hypoxic regions within experimental tumors. We found that mice bearing large, established tumors were often cured when treated with | 10-29-2015 |
Patent application number | Description | Published |
20090110690 | Hiv Gp120 Crystal Structure and Its Use to Identify Immunogens - The present disclosure relates to stabilized forms of the HIV gp120 envelope protein in complex with the broadly neutralizing CD4-binding site antibody b12, to crystalline forms of the stabilized forms of the HIV gp120 envelope protein in complex with the broadly neutralizing CD4-binding site antibody b12, and to the high resolution structure obtained from these crystals by X-ray diffraction methods. Methods for identifying immunogenic polypeptides based on these structures are also disclosed. | 04-30-2009 |
20090191235 | CONFORMATIONALLY STABILIZED HIV ENVELOPE IMMUNOGENS AND TRIGGERING HIV-1 ENVELOPE TO REVEAL CRYPTIC V3-LOOP EPITOPES - Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed. | 07-30-2009 |
20100068217 | EPITOPE-TRANSPLANT SCAFFOLDS AND THEIR USE - Computational protocols for the design of epitope-protein scaffolds which elicit selected neutralizing antibodies are disclosed, and related compositions and uses. | 03-18-2010 |
20120034254 | ANTIGENIC CLOAKING AND ITS USE - Disclosed are antigens that include a target epitope that is defined by atomic coordinates of those amino acids of the antigen that contact an antibody of interest that specifically binds the antigen. The disclosed antigens have between about 10% and about 90% of surface exposed amino acid residues located exterior of the target epitope substituted as compared to a wild-type antigen and less than about 10% of the non-surface exposed amino acid residues substituted as compared to a wild-type antigen. Also disclosed are nucleic acids encoding these antigens and methods of producing these antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject. | 02-09-2012 |
20120034255 | CONFORMATIONALLY STABILIZED HIV ENVELOPE IMMUNOGENS - Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed. | 02-09-2012 |
20120237523 | NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE - Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes. | 09-20-2012 |
20120244166 | NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE - Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and uses of these antibodies, are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes. | 09-27-2012 |
20120282264 | NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE - Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes. | 11-08-2012 |
20120328641 | CONFORMATIONALLY STABILIZED HIV ENVELOPE IMMUNOGENS - Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed. | 12-27-2012 |
20130251726 | NOVEL HIV -1 BROADLY NEUTRALIZING ANTIBODIES - The present application relates novel HIV-1 broadly neutralizing antibodies. The antibodies of the present invention are further characterized by their ability to bind epitopes from the Env proteins. The invention also provides light and heavy chain variable region sequences. Compositions for prophylaxis, diagnosis and treatment of HIV infection are provided. | 09-26-2013 |
20140322163 | NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE - Monoclonal neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed. | 10-30-2014 |
20140348865 | IMMUNOGENS BASED ON AN HIV-1 V1V2 SITE-OF-VULNERABILITY - Disclosed are HIV immunogens. Also disclosed are nucleic acids encoding these immunogens and methods of producing these antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject. | 11-27-2014 |
20150044137 | NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE - Neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed. | 02-12-2015 |
Patent application number | Description | Published |
20090002236 | Electro optical scanning phased array antenna for pulsed operation - An electro optical scanning phased array antenna having a laser which generates a pulsed output. A microwave source has an output which amplitude modulates the optical output from the laser through an optical modulator. An optical loop circuit has an input connected to an output from the optical modulator and a variable time delay element. The optical loop circuit generates a plurality of modulated optical pulses at equidistantly spaced time intervals from each other at an output from the loop circuit. These time intervals vary as a function of the variable time delay element and a control circuit controls the time delay attributable to the variable time delay element. An antenna array includes end elements while a circuit converts the optical output pulses from the optical loop circuit to radio frequency signals electrically connected to the elements of the antenna array. | 01-01-2009 |
20100259440 | Apparatus and Method for Receiving Electromagnetic Waves Using Photonics - An apparatus and method for receiving electromagnetic waves using photonics includes a transmission unit transmitting electromagnetic waves in intervals; a time delay unit coupled to the transmission unit and controlling the transmission unit to transmit the electromagnetic waves in the intervals; an antenna receiving the electromagnetic waves reflected from the target; an interferoceiver coupled to the antenna and receiving the electromagnetic waves from the antenna, the interferoceiver comprising an optical recirculation loop to produce replica electromagnetic waves; and a computer identifying the target from the reflected electromagnetic waves. | 10-14-2010 |
20110188801 | SEMICONDUCTOR HOLLOW-CORE WAVEGUIDE USING PHOTONIC CRYSTAL GRATINGS - A semiconductor hollow-core waveguide using high-contrast gratings or photonic crystal claddings and a method of manufacturing the same includes providing a layered semiconductor structure; creating an etching mask pattern over the layered semiconductor structure; performing a combined cycled directional etching process on the layered semiconductor structure in one sequence and in one lithography level to create a 3-dimensional waveguide structure; and creating a hollow air core in the layered semiconductor structure by removing to define a shape of the waveguide. The etching process comprises vertically etching a series of deep trenches on the layered semiconductor structure with precise control and varying the width of the trench. Furthermore, the hollow air core is created by removing a portion of the sacrificial material located in the center of the waveguide and under the waveguide. | 08-04-2011 |
20130202305 | METHOD AND APPARATUS FOR PROVIDING RADIO FREQUENCY PHOTONIC FILTERING - A method and apparatus for providing RF-photonic filtering link. Specifically, one embodiment is an apparatus comprising a radio frequency (RF)-photonic filter for filtering an RF signal, where the RF-photonic filter comprises a loop comprising an electro-optical modulator, an optical fiber, a photo detector. Another embodiment is a method of operating an RF-photonic filter comprising applying a reference signal to the RF-photonic filter; selecting a reference frequency for the RF-photonic filter upon the RF-photonic filter locking to the reference frequency, disconnecting the reference signal; and applying an RF input signal to the RF-photonic filter to lock the RF input signal to the RF-photonic filter. | 08-08-2013 |
20130209107 | METHOD AND APPARATUS FOR DETECTING RADIO-FREQUENCY SIGNALS USING A DISPERSIVE FIBER OPTICAL LOOP - An apparatus comprising a dispersive fiber optical loop for delaying a first and second sideband, relative to each other, of a light modulated by a radio frequency signal to create a pair of pulses, a coupler for tapping a replica of the pair of pulses from the loop; and an auto-correlation module, coupled to the coupler, for correlating the replica of the pair of pulses with each other. | 08-15-2013 |
20130315590 | Method and Apparatus for Analyzing the Spectrum of Radio-Frequency Signals Using Unamplified Fiber Optic Recirculation Loops - An apparatus for generating a frequency spectrum of an RF signal comprising a gate switch for generating a series of pulses from a laser of wavelength lambda modulated by an input RE signal, a first fiber optical loop for circulating a first percentage of a first pulse of the series of pulses from the gate switch, for a predetermined number of cycles n where each cycle takes time t | 11-28-2013 |
20140130601 | RF-PHOTONIC SYSTEM FOR ACOUSTIC AND/OR VIBRATIONAL SENSING USING OPTICAL FIBER AND METHOD THEREOF - A method and system comprising:
| 05-15-2014 |
20140133521 | Method and Apparatus for Analyzing the Spectrum of Radio-Frequency Signals Using a Fiber Optic Recirculation Loop - An apparatus comprising a fiber optical loop for conducting a first and a second pulse having a corresponding first and second wavelength, a first splitter for separating the first and second light pulses in the optical loop into a first and second light path to introduce a predetermined time delay between the first and second light pulses, a coupler for tapping a replica of the pair of light pulses from the loop, an auto-correlation module, coupled to the coupler, for correlating the replica of the pair of light pulses with each other to produce a set of data points comprising a plurality of multiplied and correlated pair of pulses and a transform module, coupled to the auto-correlation module, for transforming the data points into a channelized frequency spectrum. | 05-15-2014 |