Patent application number | Description | Published |
20090016956 | Labeled Macrophages and Methods of Use Thereof - Methods of making and using labeled macrophages are described. | 01-15-2009 |
20100169490 | LOAD-BALANCING AND TECHNOLOGY SHARING USING LEMPEL-ZIV COMPLEXITY TO SELECT OPTIMAL CLIENT-SETS - Optimal assignment of clients to client-sets, resources to resource-sets, and client-sets to resource-sets in a server farm allows for periodic re-balancing of the load as client usership and concurrent-user activity fluctuate. Unique combinations of clients are generated as candidate client-sets, and historical load measurements for clients in each candidate client-set are summed. Summed loads for the candidate client-sets are compared against available resources of resource-sets. An objective function is employed to identify optimal assignment of clients to client-sets, resources to resource-sets, and client-sets to resource-sets. | 07-01-2010 |
20100174152 | PREDICTING NEONATAL HYPERBILIRUBINEMIA - A multi-variable statistical predictive leading-indicator approach is employed for identifying newborns at risk of clinically significant hyperbilirubinemia and for determining to administer interventions to at-risk newborns. In embodiments, a multi-variable logistic regression statistical model capable of calculating a probability of clinically significant hyperbilirubinemia is generated. Using an input data set for a newborn and the multi-variable logistic regression statistical model, a probability of clinically significant hyperbilirubinemia is determined for the newborn and presented to a clinician. | 07-08-2010 |
20100324417 | MATCHING OF VIBRATORY INHALERS TO PATIENT VOCAL TRACT FOR OPTIMIZATION OF PARTICLE DISPERSION - An optimization methodology is employed to match vibratory inhaler devices having certain characteristics to the particular anatomical and acoustic properties of a patient's vocal tract, in order to achieve the most effective dispersion of a dry powder medicament using inspiratory effort of a user of the inhaler. In embodiments, optimization involves employing one or more measurements of acoustic frequency spectrum properties as well as one or more anatomical/geometric measurements of the structures comprising the particular patient's mouth, pharynx, and upper respiratory tract and matching a vibratory inhalation device that corresponds thereto. | 12-23-2010 |
20110190593 | Computerized Systems and Methods for Stability-Theoretic Prediction and Prevention of Falls - A system, methods and computer-readable media are provided for the automatic identification of patients according to near-term risk of sudden kinematic injury (falling). Embodiments of the invention are directed to event prediction, risk stratification, and optimization of the assessment, communication, and decision-making to prevent falling in humans, and in one embodiment take the form of a platform for wearable, mobile, unteathered monitoring devices with embedded decision support. Thus the aim of embodiments of the present invention relates to automatically identifying persons who are at risk for falls through the use of an inexpensive, noninvasive, portable, wearable electronic device and sensors equipped with signal-processing software and statistical predictive algorithms that calculate stability-theoretic measures derived from the digital accelerometer and gyroscope timeseries acquired by the device. The measurements and predictive algorithms embedded within the device provide for unsupervised use in the home or in general acute-care and chronic-care venues and afford a degree of robustness against variations in individual anatomy and sensor placement. In some embodiments, the present invention provides a leading indicator of near-term future abnormalities, proactively alerting the user, for example, 2 hours or more in advance, and providing the wearer and/or care providers with sufficient advance notice to enable effective preventive maneuvers to be undertaken. In one exemplary embodiment, the device is equipped with radiofrequency telecommunication capabilities that enable integration with case-management software, electronic health record decision-support systems, and consumer personal health record systems. | 08-04-2011 |
20110190650 | Computerized Systems and Methods for Stability-Theoretic Prediction and Prevention of Sudden Cardiac Death - Systems, methods and computer-readable media are provided for automatic identification of patients according to near-term risk of ventricular arrhythmias and sudden cardiac death (SCD). Embodiments of the invention are directed to event prediction, risk stratification, and optimization of the assessment, communication, and decision-making to prevent SCD, and in one embodiment take the form of a platform for wearable, mobile, unteathered monitoring devices with embedded decision support. Thus embodiments relate to automatically identifying persons at risk for arrhythmias and SCD through the use of noninvasive, portable, wearable electronic device and sensors equipped with signal-processing software and statistical predictive algorithms that calculate stability-theoretic measures derived from the digital electrocardiogram timeseries acquired by the device. The measurements and predictive algorithms embedded within the device provide for unsupervised use in the home or in general acute-care and chronic-care venues and afford a degree of robustness against variations in individual anatomy and sensor placement. | 08-04-2011 |
20110258008 | BUSINESS PROCESS MODEL DESIGN MEASUREMENT - Systems and methods are provided for aiding in the development of Business Process Model (BPM) design. A BPM Design is created by a design editor, and contains model data that describes the design. The design is stored in a datastore. Sets of measurements are derived from the model data that express measures such as complexity, maintainability, or productivity of the design. A measurement calculator derives sets of measurements based on model data from designs. A design planner accesses the datastore and makes use of measurements as an aid to BPM Design. A display generator receives measurements and processes them so that they may be displayed to a user and readily interpreted as an aid to BPM Design, development, or management. | 10-20-2011 |
20120095300 | PREDICTING NEAR-TERM DETERIORATION OF HOSPITAL PATIENTS - Methods, systems, and computer storage media are provided for predicting a probability of acute deterioration for a specific patient. Various discrete measurements are taken regarding the patient's current health. Those measurements are used to determine a PPOD score, which is displayed for clinicians. | 04-19-2012 |
20120095780 | ASSESSING CONSISTENCY OF A PATIENT'S CONTINUITY-OF-CARE RECORDS - Methods, systems, and computer storage media are provided for monitoring of the internal consistency and reliability of health information about a patient that is generated by a plurality of respondents and exchanged between more than two users of systems that store and maintain such health information. | 04-19-2012 |
20140081092 | PREDICTING NEAR-TERM DETERIORATION OF HOSPITAL PATIENTS - Methods, systems, and computer storage media are provided for predicting a probability of acute deterioration for a specific patient. Various discrete measurements are taken regarding the patient's current health. Those measurements are used to determine a PPOD score, which is displayed for clinicians. | 03-20-2014 |
20140100487 | Computerized Systems and Methods for Stability-Theoretic Prediction and Prevention of Falls - A system, methods, A system, methods and computer-readable media are provided for the automatic identification of patients according to near-term risk of sudden kinematic injury (falling). Embodiments of the invention are directed to event prediction, risk stratification, and optimization of the assessment, communication, and decision-making to prevent falling in humans, and in one embodiment take the form of a platform for wearable, mobile, unteathered monitoring devices with embedded decision support. | 04-10-2014 |
20140114583 | PREDICTING NEONATAL HYPERBILIRUBINEMIA - A multi-variable statistical predictive leading-indicator approach is employed for identifying newborns at risk of clinically significant hyperbilirubinemia and for determining to administer interventions to at-risk newborns. In embodiments, a multi-variable logistic regression statistical model capable of calculating a probability of clinically significant hyperbilirubinemia is generated. Using an input data set for a newborn and the multi-variable logistic regression statistical model, a probability of clinically significant hyperbilirubinemia is determined for the newborn and presented to a clinician. | 04-24-2014 |
20140121550 | COMPUTERIZED SYSTEMS AND METHODS FOR STABILITY-THEORECTIC PREDICTION AND PREVENTION OF SUDDEN CARDIAC DEATH - Systems, methods and computer-readable media are provided for automatic identification of patients according to near-term risk of ventricular arrhythmias and sudden cardiac death (SCD). Embodiments of the invention are directed to event prediction, risk stratification, and optimization of the assessment, communication, and decision-making to prevent SCD, and in one embodiment take the form of a platform for wearable, mobile, unteathered monitoring devices with embedded decision support. Thus embodiments relate to automatically identifying persons at risk for arrhythmias and SCD through the use of noninvasive, portable, wearable electronic device and sensors equipped with signal-processing software and statistical predictive algorithms that calculate stability-theoretic measures derived from the digital electrocardiogram timeseries acquired by the device. The measurements and predictive algorithms embedded within the device provide for unsupervised use in the home or in general acute-care and chronic-care venues and afford a degree of robustness against variations in individual anatomy and sensor placement. | 05-01-2014 |
20150193583 | Decision Support From Disparate Clinical Sources - Systems, methods and computer-readable media are provided for facilitating clinical decision support and managing patient population health by health-related entities including caregivers, health care administrators, insurance providers, and patients. Embodiments of the invention provide decision support services including providing timely contextual patient information including condition risks, risk factors and relevant clinical information that are dynamically updatable; imputing missing patient information; dynamically generating assessments for obtaining additional patient information based on context; data-mining and information discovery services including discovering new knowledge; identifying or evaluating treatments or sequences of patient care actions and behaviors, and providing recommendations based on this; intelligent, adaptive decision support services including identifying critical junctures in patient care processes, such as points in time that warrant close attention by caregivers; near-real time querying across diverse health records data sources, which may use diverse clinical nomenclatures and ontologies; improved natural language processing services; and other decision support services. | 07-09-2015 |
Patent application number | Description | Published |
20100189688 | Dose forms comprising VX-950 and their dosage regimen - The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also relates to kits and pharmaceutical packs comprising compositions and dosage forms. The invention also relates to processes for preparing these compositions, dosages, kits, and packs. | 07-29-2010 |
20100226889 | HCV Combination Therapies - The invention relates to combination therapies for the treatment of hepatitis C virus with telaprevir and pegylated interferon alfa-2a with or without ribavirin. The invention relates to the treatment of Latino and African American patients infected with HCV using the combination therapy. | 09-09-2010 |
20120039850 | HCV Combination Therapies Comprising Pegylated Interferon, Ribavirin and Telaprevir - The invention relates to combination therapies for the treatment of hepatitis C virus with telaprevir and pegylated interferon alfa-2a with or without ribavirin. The invention relates to the treatment of patients with bridging fibrosis infected with HCV using the combination therapy. | 02-16-2012 |
20120045415 | TREATMENT OF HEPATITIS C VIRUS WITH TELAPREVIR (VX-950) IN PATIENTS NON-RESPONSIVE TO TREATMENT WITH PEGYLATED INTERFERON-ALPHA 2A/2B AND RIBAVIRIN - The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also relates to kits and pharmaceutical packs comprising compositions and dosage forms. The invention also relates to processes for preparing these compositions, dosages, kits, and packs. | 02-23-2012 |
20140127160 | TREATMENT OF HEPATITIS C VIRUS WITH TELAPREVIR (VX-950) IN PATIENTS NON-RESPONSIVE TO TREATMENT WITH PEGYLATED INTERFERON-ALPHA 2A/2B AND RIBAVIRIN - The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also relates to kits and pharmaceutical packs comprising compositions and dosage forms. The invention also relates to processes for preparing these compositions, dosages, kits, and packs. | 05-08-2014 |