Roehl, DE
Christian Roehl, Kelkheim DE
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20090182532 | MONITORING UNIT FOR PHOTOVOLTAIC MODULES - The invention relates to a monitoring unit for photovoltaic modules, wherein the modules are designed for a direct conversion of radiation energy, such as e.g. solar energy, into electric energy, and the system is designed function monitored, wherein each photovoltaic module ( | 07-16-2009 |
Franz Roehl, Goennheim DE
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20140323305 | Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors - The present invention relates to the use of strobilurine type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing a mutation in the mitochondrial cytochrome b gene conferring resistance to Qo inhibitors, and to methods for combating such fungi. The invention also relates to novel compounds, processes for preparing these compounds, to compositions comprising at least one such compound, to plant health applications, and to seeds coated with at least one such compound. | 10-30-2014 |
Ingo Roehl, Memmelsdorf DE
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20080221055 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF HUNTINGTIN GENE - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Huntingtin gene (HD gene), comprising an antisense strand having a nucleotide sequence which is less than 25 nucleotides in length and which is substantially complementary to at least a part of the HD gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the HD gene, or a mutant form thereof, using the pharmaceutical composition; and methods for inhibiting the expression of the huntingtin gene in a cell. | 09-11-2008 |
20090258934 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Nav1.8 GENE - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Nav1.8 gene (Nav1.8 gene), comprising an antisense strand having a nucleotide sequence which is less that 25 nucleotides in length and which is substantially complementary to at least a part of the Nav1.8 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the Nav1.8 gene using the pharmaceutical composition; and methods for inhibiting the expression of the Nav1.8 gene gene in a cell. | 10-15-2009 |
20100298405 | Compositions And Methods For Inhibiting Expression Of Huntingtin Gene - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Huntingtin gene (HD gene), comprising an antisense strand having a nucleotide sequence which is less than 25 nucleotides in length and which is substantially complementary to at least a part of the HD gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the HD gene, or a mutant form thereof, using the pharmaceutical composition; and methods for inhibiting the expression of the huntingtin gene in a cell. | 11-25-2010 |
20110112176 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF KIF10 GENES - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a KIF10 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a KIF10 gene using said pharmaceutical composition; and methods for inhibiting the expression of KIF10 in a cell. | 05-12-2011 |
20110124711 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Nav1.8 GENE - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Nav1.8 gene (Nav1.8 gene), comprising an antisense strand having a nucleotide sequence which is less that 25 nucleotides in length and which is substantially complementary to at least a part of the Nav1.8 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the Nav1.8 gene using the pharmaceutical composition; and methods for inhibiting the expression of the Nav1.8 gene in a cell. | 05-26-2011 |
20110152349 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF IL-18 GENES - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a IL-18 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a IL-18 gene using said pharmaceutical composition; and methods for inhibiting the expression of IL-18 in a cell. | 06-23-2011 |
20110196016 | Compositions and Methods for Inhibiting Expression of IKK2 Genes - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of an IKK2 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of an IKK2 gene using said pharmaceutical composition; and methods for inhibiting the expression of IKK2 in a cell. | 08-11-2011 |
20110201006 | Oligonucleotide Detection Method - The invention relates to a method for the detection of oligonucleotides using anion exchange high performance liquid chromatography. Fluorescently labelled peptide nucleic acid oligomers, complementary to the oligonucleotide are hybridized to the oligonucleotides. Anion exchange high performance liquid chromatography is then performed and the hybridized moieties detected and quantitated. The invention also relates to a method for the simultaneous detection of both strands of an oligonucleotide in parallel from one sample, and a kit for use in qualitative and quantitative detection of one or two strands of an oligonucleotide | 08-18-2011 |
20120095076 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF HUNTINGTIN GENE - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Huntingtin gene (HD gene), comprising an antisense strand having a nucleotide sequence which is less than 25 nucleotides in length and which is substantially complementary to at least a part of the HD gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of the HD gene, or a mutant form thereof, using the pharmaceutical composition; and methods for inhibiting the expression of the huntingtin gene in a cell. | 04-19-2012 |
20120157509 | GALACTOSE CLUSTER-PHARMACOKINETIC MODULATOR TARGETING MOIETY FOR siRNA - The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to cell in vivo. The pharmacokinetic modulator improve in vivo targeting compared to the targeting ligand alone. Targeting ligand-pharmacokinetic modulator targeting moiety targeted RNAi polynucleotides can be administered in vivo alone or together with co-targeted delivery polymers. | 06-21-2012 |
20120165393 | Peptide-Based In Vivo siRNA Delivery System - The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted melittin delivery peptides. Delivery peptides provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery peptides. | 06-28-2012 |
20120172412 | In Vivo Polynucleotide Delivery Conjugates Having Enzyme Sensitive Linkages - The present invention is directed compositions for delivery of RNA interference (RNAi) polynucleotides to cells in vivo. The compositions comprise amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or DPC) are further covalently linked to an RNAi polynucleotide or co-administered with a targeted RNAi polynucleotide-targeting molecule conjugate. | 07-05-2012 |
20130190484 | In Vivo Polynucleotide Delivery Conjugates Having Enzyme Sensitive Linkages - The present invention is directed compositions for delivery of RNA interference (RNAi) polynucleotides to cells in vivo. The compositions comprise amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or DPC) are further covalently linked to an RNAi polynucleotide or co-administered with a targeted RNAi polynucleotide-targeting molecule conjugate. | 07-25-2013 |
20140135380 | Small molecule conjugates for intracellular delivery of nucleic acids - The invention provides use of novel compounds for delivery of nucleic acids, and conjugates of these compounds with nucleic acids. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to said compounds and co-administered with a delivery polymer to achieve mRNA knock down in vivo are disclosed therein. | 05-15-2014 |
20140135381 | Small molecule conjugates for intracellular delivery of biologically active compounds - The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein. | 05-15-2014 |
Maik Roehl, Hoexter DE
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20100282665 | FILTER CAPSULE - A filter capsule has a filter housing which, on at least one end face, has an end cap with an air release valve. A protective wall is formed on the end cap at a distance from the air release valve and protrudes beyond the air release valve. | 11-11-2010 |
Manfred Roehl, Bruckmuehl DE
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20100045199 | IGNITION TRANSFORMER FOR A DISCHARGE LAMP - An ignition transformer for a discharge lamp is provided having a transformer core whose material and dimensions are selected in such a manner that the Curie temperature of the material after the ignition which is achieved by means of the ignition transformer can be achieved by a voltage drop across a secondary winding of the ignition transformer. | 02-25-2010 |
20100134010 | INTEGRATED GAS DISCHARGE LAMP - Various embodiments relate to an integrated gas discharge lamp including a lamp base, a gas discharge lamp burner and an ignition electronics, wherein the integrated gas discharge lamp includes an operation electronics for operating the gas discharge lamp burner, and the gas discharge lamp burner, the ignition electronics, and the operation electronics are unseparably coupled with each other. | 06-03-2010 |
20100213809 | HEADLAMP AND ITS USE - A headlamp is provided having a cap and a light output which is predetermined by international standardization with respect to the distance and position with respect to a reference plane of the cap, wherein the light output is provided by one or more semiconductor light sources. | 08-26-2010 |
Martin Roehl, Hildesheim DE
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20090174988 | Holding device for mounting a display unit, a display unit and display device - A holding device for installing a display unit, having a holding element and receiving elements connected to the holding element, which have essentially wedge- or v-shaped recesses, which are used to accommodate axial sections of the display unit having a corresponding wedge-type design; display unit and mounting system. It is advantageous that the display unit and holding device are separated in a simple manner. This separation in turn has the advantage of facilitating the installation of the display device and, if required, also a subsequent de-installation of the display unit or the entire display device. In particular, this is achieved in that the holding device for accommodating the monitor or the display unit is mounted separately therefrom, and the monitor is able to be installed in the holding device at a later time. A holding device for installing the display unit, which includes a holding element and receiving elements connected to the holding element, which have essentially wedge- or v-shaped recesses that are provided to receive correspondingly wedge-shaped axial sections of the display unit. Even after several installation and/or de-installation cycles, this allows a play-free and thus rattle-free installation of the display unit. | 07-09-2009 |
Olaf Roehl, Aachen DE
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20100083934 | Combustion Method for a Reciprocating Piston Internal Combustion Engine - A reciprocating engine includes a combustion chamber, and a gas exchange inlet valve and a gas exchange outlet valve for a charge cycle. The method introduces an inlet gas into the combustion chamber in an intake phase; introduces a primary quantity of fuel into the combustion chamber during the intake phase and/or a compression phase; compresses the inlet gas and the fuel in the compression phase; ignites a mixture of inlet gas and fuel formed in the combustion chamber; and expands and discharges an exhaust gas formed by the combustion in an expansion phase. A pilot quantity of fuel is introduced into the combustion chamber before the primary quantity of fuel is introduced. Intermediate products of the pilot quantity of fuel are formed and the primary quantity of fuel is introduced into the combustion chamber during the compression phase such that complete ignition of the mixture consisting of inlet gas and the intermediate products is suppressed and other intermediate products are formed until a controlled ignition of the mixture and other intermediate products occurs. | 04-08-2010 |
Olaf Roehl, Stuttgart DE
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20120266848 | Lean Combustion Method for a Reciprocating Internal Combustion Engine - A lean combustion method is provided for a four-stroke reciprocating internal combustion engine having a cylinder, in which a combustion chamber is delimited by a cylinder head and a piston is movable in a reciprocating manner, the piston being able to vary the volume of the combustion chamber. A fuel can be introduced directly into the combustion chamber, and at least one gas exchange inlet valve and one gas exchange outlet valve are provided for a gas exchange. An intermediate compression can be set in the combustion chamber at a gas exchange top dead center and a main compression can be set at an ignition top dead center. | 10-25-2012 |
Oliver Roehl, Schlierbach DE
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20130233481 | METHOD AND DEVICE FOR THE CONTINUOUS WELDING OF PLASTIC CO - For continuous welding of plastic components ( | 09-12-2013 |
20130269871 | LASER WELDING PLASTIC PARTS WITH TWO DEGREES OF FREEDOM - The invention relates to a joining device ( | 10-17-2013 |
Stefan Roehl, Munich DE
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20140212631 | PRINTING ARRANGEMENT FOR TWO-SIDED PRINTING ON A RECORDING MEDIUM AND PRINTING METHOD - A printing arrangement and printing method are disclosed for two-sided printing on a recording medium, in which intermediate fixing by superheated steam takes place after printing on the first side of the recording medium. Owing to the intermediate fixing, damage to the print image of the first side during subsequent printing on the second side is avoided without the recording medium being impaired by the intermediate fixing. | 07-31-2014 |
20140212632 | PRINTING ARRANGEMENT FOR TWO-SIDED PRINTING ON A RECORDING MEDIUM AND PRINTING METHOD - A printing arrangement and a printing method for two-sided printing on a recording medium are disclosed, in which conditioning by steam and/or liquid droplets takes place after printing on the first side of the recording medium. Because of the conditioning, damage is avoided to the print image of the first side during subsequent printing on the second side, without the recording medium being impaired by the conditioning. | 07-31-2014 |
Stefan Roehl, Muenchen DE
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20110299905 | DEVICE AND METHOD TO FIX PRINT IMAGES ON A RECORDING MATERIAL - In a device or method to fix print images on a recording material, a printing fluid comprising a carrier fluid and chromophoric solid particles are applied to the recording material, the chromophoric solid particles being applied in a form of the print images to be fixed. Hot waste gas and infrared radiation are generated with aid of a porous burner. The infrared radiation is directed towards the recording material in a drying chamber such that the carrier fluid polymerizes or is vaporized, whereby a gaseous air/oil mixture arises in the drying chamber. The air/oil mixture is influenced with aid of the hot waste gas of the porous burner. | 12-08-2011 |
Thomas Roehl, Hamburg DE
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20090193912 | SAMPLING OF INDIVIDUAL ROD-LIKE ARTICLES OF THE TOBACCO-PROCESSING INDUSTRY FROM A MASSFLOW - Method for sampling individual rod-like articles of the tobacco-processing industry from an article massflow via a sampling unit. The article massflow includes a plurality of rod-like articles arranged longitudinally and axially parallel to each other and is conveyed along a conveying section at a predetermined conveyor speed. The method includes moving the sampling unit parallel to a conveyor direction of the article massflow, capturing at least one individual rod-like article from the article massflow with the sampling unit, and removing the captured at least one individual rod-like article from the article massflow in a direction at an angle to the conveyor direction of the article massflow. | 08-06-2009 |