Zhao, NJ
Bao-Ping Zhao, West Windsor, NJ US
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20090069305 | Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor - The present invention relates to substituted nitrogen-containing heteroaryl derivatives, pharmaceutical compositions containing them, and methods of using any of these derivatives and compositions for H | 03-12-2009 |
20090171089 | 1,6 NAPHTHRIDINES USEFUL AS INHIBITORS OF SYK KINASE - Disclosed are compounds of formula (I): | 07-02-2009 |
20110150864 | SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I), | 06-23-2011 |
20110200586 | AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I), | 08-18-2011 |
20110200587 | AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I), | 08-18-2011 |
20110294780 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS - The present invention relates to compounds of Formula (I), | 12-01-2011 |
20120302544 | SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I), | 11-29-2012 |
20120302610 | PICOLINAMIDO-PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS - The present invention is directed to picolanmido-propanoic acid derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity. | 11-29-2012 |
20140256657 | DUAL SGLT1/SGLT2 INHIBITORS - The present invention relates to compounds of Formula (I), | 09-11-2014 |
Baozhong Zhao, Livingston, NJ US
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20090022635 | High-performance cracker - A furnace for thermally cracking hydrocarbon process fluid is provided. The furnace comprises a convection section including a plurality of convection sub-sections, a radiant section comprising a plurality of radiant sub-sections, and an enclosure defining a plurality of discrete sectors. Each discrete sector of the enclosure includes a convection sub-section having at least one convection conduit for carrying hydrocarbon process fluid, at least one radiant sub-section having at least one radiant conduit connected to receive preheated hydrocarbon process fluid from the convection conduit, and a heat source configured to deliver heat into the discrete sector. Adjacent sectors of the furnace are segregated from each other, such that the heat delivered from the heat source is substantially localized in the discrete sector of the enclosure. | 01-22-2009 |
20110289940 | LIQUID NATURAL GAS VAPORIZATION - A process for the vaporization of a cryogenic liquid is disclosed. The process may include: combusting a fuel in a burner to produce an exhaust gas; admixing ambient air and the exhaust gas to produce a mixed gas; contacting the mixed gas via indirect heat exchange with a cryogenic liquid to vaporize the cryogenic liquid. Also disclosed is a system for vaporization of a cryogenic liquid. The system may include: one or more burners for combusting a fuel to produce an exhaust gas; one or more inlets for admixing ambient air with the exhaust gas to produce a mixed gas; and one or more heat transfer conduits for indirectly heating a fluid with the mixed gas. | 12-01-2011 |
Bilie Zhao, East Hanover, NJ US
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20150073967 | TRANSMISSION LATENCY LEVELING APPARATUSES, METHODS AND SYSTEMS - Embodiments of the transmission latency leveling apparatuses, methods and systems provide an electronic bidding order management infrastructure, such as a “point-of-presence,” which receives and routes electronic trading orders from different trading entities at a server via a transmission medium to create a certain amount of transmission latency before the trading orders could arrive at and be executed at electronic exchanges to reduce latency arbitrage and/or order book arbitrage that may be experienced by high frequency trading participants. A similar transmission latency may be applied to the egress transmission of market data updates issued by an electronic exchange. Other techniques for facilitating electronic trading are also disclosed. | 03-12-2015 |
20150302441 | SYSTEMS AND METHODS FOR PROVIDING UP-TO-DATE INFORMATION FOR TRANSACTIONS - In a system for executing transaction requests, a received request for a transaction in an item is delayed prior to matching that request with another request for transaction in that item by a delay based on a communication delay and/or a processing delay. The communication delay represents the time required to receive updated information about the item and the processing delay represents the time required to compute an updated item price using the received updated information. | 10-22-2015 |
Bixiao Zhao, Plainsboro, NJ US
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20140127126 | Compositions and Methods for Assessing and Treating Adrenal Diseases and Disorders - The present invention relates to the discovery that mutations in KCNJ5 are associated with adrenal diseases and disorders. The invention includes compositions and methods for the assessment, characterization and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder. | 05-08-2014 |
Bo Zhao, Gainesville, NJ US
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20140300959 | TELESCOPE AND TELESCOPE ARRAY FOR USE IN SPACECRAFT - A catadioptric telescope is a modified version of a conventional Maksutov-Cassegrain optical telescope. In accordance with the invention, the reflecting surfaces of the primary mirror and the secondary spot mirror are on the second surfaces of the primary mirror and correcting lens, respectively. In further accordance with the invention, two of these telescopes can be joined together to form a binocular telescope array. The array can be easily customized to suit different remote sensing/satellite applications. | 10-09-2014 |
Chunlin Zhao, Livingston, NJ US
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20090111789 | CHIRAL CIS-IMIDAZOLINES - There are provided compounds of the formula | 04-30-2009 |
20140148443 | Novel Imidazolines as dual inhibitors of MDM2 and MDMX - Disclosed are compounds of Formula I | 05-29-2014 |
Dalian Zhao, Fanwood, NJ US
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20080221198 | Novel Crystalline Forms of Antidiabetic Compounds - Novel crystalline forms of two indole compounds connected to phenoxyalkylcarboxylic acid groups are selective PPAR gamma partial agonists that are useful in the treatment of type 2 diabetes, hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. The novel crystal forms include a crystalline free acid dihydrate and crystalline free acid anhydrate of one compound and several crystalline forms of the free acid and the sodium salt of the second compound. The invention also relates to pharmaceutical compositions comprising these novel crystal forms, processes to prepare the crystal forms and their pharmaceutical compositions, and uses of the crystal forms in the treatment of type 2 diabetes and other PPAR gamma modulated diseases. | 09-11-2008 |
20100292282 | SYNTHESIS AND CRYSTALLINE FORMS OF CB-1 ANTAGONIST/INVERSE AGONIST - The present invention relates to a process for producing crystalline 3-[(1S)-1-(1-{(S)-(4-chlorophenyl)[3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl]methyl}azetidin-3-yl)-2-fluoro-2-methyl-propyl]-5-fluorobenzonitrile, and novel salts, solvates, hydrates and polymorphs thereof. | 11-18-2010 |
Guohua Zhao, Princeton, NJ US
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20090221548 | MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS - The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I | 09-03-2009 |
20110195934 | AZOLOPYRROLONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS - The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable faints thereof according to | 08-11-2011 |
20110195986 | PYRROLONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS - The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I | 08-11-2011 |
20150218093 | PYRROLONE OR PYRROLIDINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS - The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments. | 08-06-2015 |
20150315144 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS - The present invention provides compounds of Formula (I): | 11-05-2015 |
20160031816 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS - The present invention provides compounds of Formula (I): | 02-04-2016 |
Haixiong Zhao, Holmdel, NJ US
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20130122897 | DETACHABLE WIRELESS TERMINAL - A limited-capability wireless terminal that is particularly well adapted for use in emergency situations, recreational activities and occasional calls is disclosed. The detachable wireless terminal does not have a display or a numeric keypad. Rather, the detachable wireless terminal has several “one-touch” buttons that place a call to pre-programmed phone numbers when pressed. The detachable wireless terminal is small enough and light enough to be worn around a user's neck, received by a lanyard or a necklace. The wireless terminal detachably couples to a relatively larger docking device, which can be used to program it. | 05-16-2013 |
Jian H. Zhao, North Brunswick, NJ US
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20100148224 | POWER JUNCTION FIELD EFFECT POWER TRANSISTOR WITH HIGHLY VERTICAL CHANNEL AND UNIFORM CHANNEL OPENING - A semiconductor vertical junction field effect power transistor formed by a semiconductor structure having top and bottom surfaces and including a plurality of semiconductor layers with predetermined doping concentrations and thicknesses and comprising at least a bottom layer as drain layer, a middle layer as blocking and channel layer, a top layer as source layer. A plurality of laterally spaced U-shaped trenches with highly vertical side walls defines a plurality of laterally spaced mesas. The mesas are surrounded on the four sides by U-shaped semiconductor regions having conductivity type opposite to that of the mesas forming U-shaped pn junctions and defining a plurality of laterally spaced long and vertical channels with a highly uniform channel opening dimension. A source contact is formed on the top source layer and a drain contact is formed on the bottom drain layer. A gate contact is formed on the bottom of the U-shaped trenches for the purpose of creating and interrupting the vertical channels so as to turn on and turn off the transistor. | 06-17-2010 |
Jianhong Zhao, Annadale, NJ US
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20100113462 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS - The present invention relates to novel compounds of the formula I: | 05-06-2010 |
Jonathan Zhao, Belle Mead, NJ US
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20080241215 | LOCAL VASCULAR DELIVERY OF PROBUCOL ALONE OR IN COMBINATION WITH SIROLIMUS TO TREAT RESTENOSIS, VULNERABLE PLAQUE, AAA AND STROKE - Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices. | 10-02-2008 |
Jonathon Z. Zhao, Belie Mead, NJ US
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20110029070 | ADHESION PROMOTING PRIMER FOR COATED SURFACES - An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to the tissue. For treatment of conditions such as restenosis, different agents are loaded into different openings in the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different agents may also be used to address different diseases from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute thrombosis. To ensure that the different agents remain affixed to the device as well as to each other, primer layers may be utilized. | 02-03-2011 |
Jonathon Z. Zhao, Belle Meade, NJ US
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20090125101 | POLYMERIC MATERIALS FOR MEDICAL DEVICES - The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a surface thereof contain a film-forming fluorous homo-polymer or copolymer containing the polymerized residue of a fluorous moiety, wherein the relative amounts of the polymerized residues of one or more moieties are effective to provide the coating and films with properties effective for use in coating implantable med devices. | 05-14-2009 |
20120276172 | POLYMERIC MATERIALS FOR MEDICAL DEVICES - The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a surface thereof contain a film-forming fluorous homo-polymer or copolymer containing the polymerized residue of a fluorous moiety, wherein the relative amounts of the polymerized residues of one or more moieties are effective to provide the coating and films with properties effective for use in coating implantable med devices. | 11-01-2012 |
20150044268 | POLYMERIC MATERIALS FOR MEDICAL DEVICES - The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a surface thereof contain a film-forming fluorous homo-polymer or copolymer containing the polymerized residue of a fluorous moiety, wherein the relative amounts of the polymerized residues of one or more moieties are effective to provide the coating and films with properties effective for use in coating implantable med devices. | 02-12-2015 |
20150044269 | POLYMERIC MATERIALS FOR MEDICAL DEVICES - The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a surface thereof contain a film-forming fluorous homo-polymer or copolymer containing the polymerized residue of a fluorous moiety, wherein the relative amounts of the polymerized residues of one or more moieties are effective to provide the coating and films with properties effective for use in coating implantable med devices. | 02-12-2015 |
Joyce Zhao, Nanuet, NJ US
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20100280462 | Luer Slip Connector with Roughened Tip - Medical devices with male luer slip fittings with either a male conical tip having a roughened outer surface or a female luer fitting with a roughened surface and methods for manufacture and use are disclosed. The outer surface of the male conical tip or a surface of the female luer fitting is roughened to increase the force required to remove the male luer fitting from the female luer fitting without causing leakage of the connection. | 11-04-2010 |
Kake Zhao, Westfield, NJ US
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20130331372 | Cyclic Amine Substituted Oxazolidinone CETP Inhibitor - Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compound of Formula I, A | 12-12-2013 |
20140057893 | SUBSTITUTED CYCLOPROPLY COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT - Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included | 02-27-2014 |
20140357632 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS - Compounds having the structure of Formula Ia, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and may be useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. | 12-04-2014 |
Liming Zhao, Jersey City, NJ US
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20110009241 | VIRTUAL LOCOMOTION CONTROLLER APPARATUS AND METHODS - Apparatus and methods are disclosed for a virtual locomotion controller user interface and system that combines data obtained from various sensor devices to allow users to control the movements of their representation in a virtual world using sensorimotor responses closely resembling the tasks and actions they would physically perform in the real world. As a result, users can specify an avatar's locomotion style by assuming body postures normally associated with that type of movement, while controlling locomotion speed or displacement through foot forces and/or stepping motions and locomotion direction through foot and body orientation. | 01-13-2011 |
Matthew Zhao, Edison, NJ US
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20090186928 | Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 - Novel crystalline salts of 3-[1-(4-chlorophenyl)-trans-3-fluorocyclobutyl]-4,5-dicyclopropyl-r-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment. | 07-23-2009 |
Matthew Mangzhu Zhao, Edison, NJ US
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20090030198 | METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS - Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I: | 01-29-2009 |
20090099206 | SOLID FORMS OF (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-2,2,2-TRIFLUORO-1-(3'-METHOXYBIPHENYL-4-- YL)ETHOXY)PYRIMIDIN-4-YL)PHENYL)PROPANOIC ACID AND METHODS OF THEIR USE - Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-2,2,2-trifluoro-1-(3′-methoxybiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid and salts thereof are disclosed. | 04-16-2009 |
20090118505 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALANINES - Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed: | 05-07-2009 |
20100016422 | SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETR- AHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE - Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders. | 01-21-2010 |
20110124865 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALANINES - Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds are disclosed. | 05-26-2011 |
20110130564 | COMPOUNDS USEFUL IN THE PREPARATION OF TRYPTOPHAN HYDRROXYLASE INHIBITORS - Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed: | 06-02-2011 |
20120095197 | METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS - Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I: | 04-19-2012 |
20120122904 | SOLID FORMS OF (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-1-(4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)- PHENYL)-2,2,2-TRIFLUOROETHOXY)PYRIMIDIN-4-YL)PHENYL)PROPANOIC ACID - Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid and salts thereof are disclosed. Pharmaceutical dosage forms and methods of their use are also disclosed. | 05-17-2012 |
20130165395 | METHODS OF TREATING DIABETES - Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders. | 06-27-2013 |
Miao Zhao, Bedminster, NJ US
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20130144984 | Systems and Methods for Connection Pooling for Video Streaming in Content Delivery Networks - System and methods for connection pooling for video streaming in content delivery networks (CSNs) are provided. An embodiment method for connection pooling in a content delivery network (CDN) by a proxy server includes receiving, from a client, a request for media content, sending, to a control server, a query to locate an origin media server having the media content if the media content is cache-missing, receiving, from the control server, information regarding the origin media server having the media content requested by the client, and forwarding the request for the media content to the origin media server having the media content using a reusable connection from a pool of the reusable connections between the proxy server and the origin media server if the reusable connection is unoccupied. | 06-06-2013 |
Na Zhao, Belle Mead, NJ US
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20100104637 | TABLET FORMULATIONS CONTAINING 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE SALTS AND TABLETS MADE THEREFROM - Pharmaceutical formulations containing a salt of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, which are suitable for forming into a tablet dosage form, as well as tablet dosage forms are disclosed. Disclosed also are methods of treatment utilizing such dosage forms. | 04-29-2010 |
20130122088 | TABLET FORMULATIONS CONTAINING 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE SALTS AND TABLETS MADE THEREFROM - Pharmaceutical formulations containing a salt of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, which are suitable for forming into a tablet dosage form, as well as tablet dosage forms are disclosed. Disclosed also are methods of treatment utilizing such dosage forms. | 05-16-2013 |
20150283121 | TABLET FORMULATIONS CONTAINING 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE SALTS AND TABLETS MADE THEREFROM - Pharmaceutical formulations containing a salt of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, which are suitable for forming into a tablet dosage form, as well as tablet dosage forms are disclosed. Disclosed also are methods of treatment utilizing such dosage forms. | 10-08-2015 |
Philip Zhao, Fort Lee, NJ US
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20140350576 | Apparatus and method for fascial closure device for laparoscopic trocar port site and surgery - A suture placement device is inserted into an endoscopic trocar port site. A pivot bar with a pair of receptor ports is moved from a folded to an extended position below the fascia. The trocar port is removed over the device as the pivot bar is pulled upward against the fascia. A pair of stylet guides are deployed from two sides of the device housing, and intercept the receptor ports, thereby creating a suture path through the first guide, through a channel in the pivot bar between the receptor ports, and through the second guide. A stylet is directed through the suture path to pull a suture through the path. The guides are refracted, the pivot bar is folded, the device is removed, and the suture is tied. A stylet guide may have a partially deployed position to accurately inject an anesthetic at a desired intra-muscular layer. | 11-27-2014 |
20150362828 | ENCASEMENT PLATFORM FOR SMARTDEVICE FOR ATTACHMENT TO ENDOSCOPE - A case or encasement for use with a smartdevice, such as a smartphone or tablet and an endoscope is disclosed. The encasement includes a power supply, logic for controlling wireless communications, a light source, and other accessories, for use with an endoscope. In an embodiment, the encasement includes a power supply that may be used to charge a smartdevice, power a light source and a wireless communications module. Other embodiments include a mechanism for communicating between the smartdevice and the encasement to control the light source and any other accessories coupled to the encasement. | 12-17-2015 |
Qi Zhao, Short Hills, NJ US
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20110154119 | Device and Method for Detecting and Diagnosing Correlated Network Anomalies - A device detects and diagnoses correlated anomalies of a network. The device includes an anomaly detection module receiving a first data stream including an event-series related to the network. The anomaly detection module executes at least one algorithm to detect a potential anomaly in the event-series. The device further includes a correlating module receiving a second data stream including other event-series related to the network. The correlating module determines whether the potential anomaly is false and determines whether the potential anomaly is a true anomaly. | 06-23-2011 |
20110307913 | Modeling User Activity Information Associated with a Network System - Systems and methods to model user activity information associated with a network system are provided. A particular method includes receiving, at a computing device, a request for user activity information associated with selected channels of a television access network that provides multimedia content to users. The method includes executing a model of user activity associated with the television access network at the computing device. The model estimates the user activity information as user multimedia access demands during particular time periods within a day. The method also includes storing the user activity information at a computer-readable non-transitory storage medium. | 12-15-2011 |
20130124923 | Device and Method for Detecting and Diagnosing Correlated Network Anomalies - A device detects and diagnoses correlated anomalies of a network. The device includes an anomaly detection module receiving a first data stream including an event-series related to the network. The anomaly detection module executes at least one algorithm to detect a potential anomaly in the event-series. The device further includes a correlating module receiving a second data stream including other event-series related to the network. The correlating module determines whether the potential anomaly is false and determines whether the potential anomaly is a true anomaly. | 05-16-2013 |
Qi Zhao, Park Ridge, NJ US
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20140143710 | SYSTEMS AND METHODS TO CAPTURE AND SAVE CRITERIA FOR CHANGING A DISPLAY CONFIGURATION - An example method for displaying clinical content includes monitoring user interaction with an image viewer displaying clinical content to a user according to a hanging protocol. The example method includes identifying a change in configuration of the hanging protocol and capturing, based on user input, criteria associated with the change. The example method includes saving the criteria in association with the hanging protocol and providing the saved hanging protocol and associated criteria for selection and application to clinical content to be displayed. | 05-22-2014 |
Qiuxia Zhao, Bridgewater, NJ US
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20110312934 | 2-ALKYL-6-CYCLOAMINO-3-(PYRIDIN-4-YL)IMIDAZO[1,2-B]-PYRIDAZINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF - The invention relates to 2-alkyl-6-cycloamino-3-(pyridin-4-yl)imidazo[1,2-b]pyridazine derivatives of the general formula (I) where: R | 12-22-2011 |
20130190314 | DERIVATIVES OF 6-CYCLOAMINO-2-THIENYL-3-(PYRIDIN-4-YL)IMIDAZO[1,2-b]-PYRIDAZINE AND 6-CYCLOAMINO-2-FURANYL-3-(PYRIDIN-4-YL)IMIDAZO[1,2-b]-PYRIDAZINE, PREPARATION AND THERAPEUTIC USE THEREOF - The invention relates to derivatives of 6-cycloamino-2-thienyl-3-(pyridin-4-yl)imidazo[1,2-b]-pyridazine and 6-cycloamino-2-furanyl-3-(pyridin-4-yl)imidazo[1,2-b]-pyridazine with general formula (I). The invention also relates to a method for the preparation and therapeutic application thereof, in the treatment or prevention of illnesses involving casein kinase 1 epsilon and/or casein kinase 1 delta. | 07-25-2013 |
Qiuxia Zhao, Green Brook, NJ US
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20100179154 | 6-CYCLOAMINO-3-(PYRID-4-YL)IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF - The invention relates to the 6-cycloamino-3-(pyridin-4-yl)imidazo[I,2-b]pyridazine derivatives corresponding to general formula (I): | 07-15-2010 |
20130012516 | 6-CYCLOAMINO-3-(PYRID-4-YL)IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF - The invention relates to the 6-cycloamino-3-(pyridin-4-yl)imidazo[I,2-b]pyridazine derivatives corresponding to general formula (I): | 01-10-2013 |
Renbin Zhao, Plainsboro, NJ US
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20100040707 | INGESTIBLE COMPOSITIONS CONTAINING EXTRACTS - The present invention relates to ingestible compositions containing | 02-18-2010 |
20100221364 | COMPOSITIONS AND METHODS OF INDUCING HAIR GROWTH UTILIZING COTINUS COGGYGRIA - This application relates to compositions and methods for inducing hair growth and improving hair quality utilizing extracts of | 09-02-2010 |
Rulin Zhao, Pennington, NJ US
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20080275092 | ARYL-SUBSTITUTED PYRAZOLE-AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - The present invention relates to compounds having the formula, | 11-06-2008 |
20100016320 | ARYL-SUBSTITUTED PYRAZOLE-AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - The present invention relates to compounds having the formula, | 01-21-2010 |
20100113489 | MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY, CRYSTALLINE FORMS AND PROCESS - The present invention provides a novel antagonist or partial agonists/antagonist of MCP-1 receptor activity: N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin- 4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide, or a pharmaceutically acceptable salt, solvate or prodrug, thereof, having an unexpected combination of desirable pharmacological characteristics. Crystalline forms of the present invention are also provided. Pharmaceutical compositions containing the same and methods of using the same as agents for the treatment of inflammatory diseases, allergic, autoimmune, metabolic, cancer and/or cardiovascular diseases is also an objective of this invention. The present disclosure also provides a process for preparing compounds of Formula (I), including N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide: | 05-06-2010 |
20110077400 | PROCESSES FOR PREPARING TETRAHYDROISOQUINOLINES - Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form. | 03-31-2011 |
20130060027 | TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR - Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form. | 03-07-2013 |
20150191494 | TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR - Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form. | 07-09-2015 |
Shubin Zhao, Jersey City, NJ US
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20140372473 | UNSUPERVISED EXTRACTION OF FACTS - A system and method for extracting facts from documents. A fact is extracted from a first document. The attribute and value of the fact extracted from the first document are used as a seed attribute-value pair. A second document containing the seed attribute-value pair is analyzed to determine a contextual pattern used in the second document. The contextual pattern is used to extract other attribute-value pairs from the second document. The extracted attributes and values are stored as facts. | 12-18-2014 |
20140372478 | Learning Objects And Facts From Documents - A system, method, and computer program product for learning objects and facts from documents. Embodiments of the method comprise selecting a source object and a source document and identifying a title pattern and a contextual pattern based on the source object and the source document. A set of documents matching the title pattern and the contextual pattern are selected. For each document in the selected set, a name and one or more facts are identified by applying the title pattern and the contextual pattern to the document. Objects are identified or created based on the identified names and associated with the identified facts. | 12-18-2014 |
20150317367 | CORROBORATING FACTS IN ELECTRONIC DOCUMENTS - A query is defined that has an answer formed of terms from electronic documents. A repository having facts is examined to identify attributes corresponding to terms in the query. The electronic documents are examined to find other terms that commonly appear near the query terms. Hypothetical facts representing possible answers to the query are created based on the information identified in the fact repository and the commonly-appearing terms. These hypothetical facts are corroborated using the electronic documents to determine how many documents support each fact. Additionally, contextual clues in the documents are examined to determine whether the hypothetical facts can be expanded to include additional terms. A hypothetical fact that is supported by at least a certain number of documents, and is not contained within another fact with at least the same level of support, is presented as likely correct. | 11-05-2015 |
Shubin Zhao, Chatham, NJ US
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20110225076 | METHOD AND SYSTEM FOR DETECTING FRAUDULENT INTERNET MERCHANTS - Systems and methods for detecting fraudulent merchants using the content of orders completed by the merchants. A fraud detection engine of a fraud detection system generates a fraud detection model using feature data extracted from order content data for known fraudulent and known non-fraudulent merchants. The fraud detection engine executes the model using feature data extracted from order content data for a target merchant to determine a fraud risk associated with the target merchant. If the fraud risk of the merchant is indicative of a fraudulent merchant, the fraud detection system can issue a request to a fraud analyst to review the target merchant further. The results of the fraud analyst's review can be used to update the fraud detection model. | 09-15-2011 |
Tao Zhao, Plainsboro, NJ US
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20100034423 | SYSTEM AND METHOD FOR DETECTING AND TRACKING AN OBJECT OF INTEREST IN SPATIO-TEMPORAL SPACE - The present invention provides a system and method for detecting and tracking a moving object. First, robust change detection is applied to find initial candidate regions in consecutive frames. These initial detections in consecutive frames are stacked to produce space-time bands which are extracted by Hough transform and entropy minimization based band detection algorithm. | 02-11-2010 |
20120207353 | System And Method For Detecting And Tracking An Object Of Interest In Spatio-Temporal Space - The present invention provides a system and method for detecting and tracking a moving object. First, robust change detection is applied to find initial candidate regions in consecutive frames. These initial detections in consecutive frames are stacked to produce space-time bands which are extracted by Hough transform and entropy minimization based band detection algorithm. | 08-16-2012 |
Wenbiao Zhao, Jersey City, NJ US
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20090177480 | System And Method For Identifying Targeted Consumers Using Partial Social Security Numbers - A system and method are used to identify a targeted consumer. The system includes a partial social security number (SSN) system that identifies a partial SSN issued during a preselected time period and a marketing database system. The marketing database system receives a comparison result from a SSN matching system that identifies at least one individual in a consumer database having a partial SSN that matches the partial SSN identified by the partial SSN system. The marketing database system places identifying information of the at least one individual in a marketing database. In one method, an individual is identified as a targeted consumer based on the individual's age being within a preselected age range and the individual's social security number being issued within a predetermined social security number SSN issue date range. Identifying information of the targeted consumer is stored in a contact database, which a business may use to directly market its goods or services. | 07-09-2009 |
Wenjie Zhao, Princeton, NJ US
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20090290508 | Method for optimizing network "Point of Presence" locations - A methodology for optimizing the placement of network “Points of Presence” (POPs) across the carrier's entire network (i.e., a “global” solution”) utilizes carefully constructed customer clustering and simulated annealing methodology to create a cost-efficient solution. The customer base is first partitioned into a plurality of clusters such that the customers within each cluster are closer to its centroid than the centroid of any other cluster (e.g., applying the k-means clustering algorithm or any other suitable method of partitioning the customer base). A linear algorithm process is used to minimize the costs associated with the number of placement of POPs within each cluster. A simulated annealing (SA) process is then used to iterate the entire set of potential POP locations until a compact, steady-state solution is achieved (or, alternatively, until a given number of iterations has been performed). In a preferred embodiment, a number of iterations are performed at each “temperature” in the simulating annealing process to further improve the result (this iterative process referred to in the art as “intensification”). | 11-26-2009 |
20100120440 | Method and apparatus for joint optimization of dedicatedand radio access networks - A computerized method and system for integrated access network business planning for a telecommunications carrier. The invention enables a user to input a set of network business planning parameters that are utilized by a linear programming model to jointly optimize a carrier's dedicated and radio access network by executing a plurality of network optimization models and determine network configuration changes for the dedicated and radio access networks as a constrained optimization based on the set of business planning parameters. | 05-13-2010 |
20100157808 | METHOD AND APPARATUS FOR DESIGNING RADIO ACCESS NETWORKS INCLUDING BROADBAND WIRELESS LINKS - A technique for reducing costs associated with a radio access network of a mobile telecommunications network includes configuring the radio access network using a linear programming model of the radio access network subject to constraints. The technique includes selecting cellular sites and hub locations of the radio access network to be connected by broadband wireless links based on the linear programming model and constraints. In at least one embodiment of the invention, a method of designing a radio access network of links between a cellular site and a core network includes selecting at least one first link of the radio access network to be at least one first wireless link at least partially based on a linear programming model of the radio access network. The method includes configuring an output device of a computer system to indicate the selection. | 06-24-2010 |
20100157841 | METHOD AND APPARATUS FOR DETERMINING BANDWIDTH REQUIREMENT FOR A NETWORK - A method and apparatus for determining a bandwidth requirement for a network are disclosed. For example, the method gathers data for one or more types of traffic, and determines an optimal traffic model for each of the one or more types of traffic in accordance with the data and one or more traffic model adaptation rules for each of the one or more types of traffic. The method then determines a demand forecast for each of the one or more types of traffic by applying the optimal traffic model for each of the one or more types of traffic, and determines a bandwidth requirement for the one or more types of traffic in accordance with the demand forecast. | 06-24-2010 |
20110085467 | Method and Apparatus for Clustering Based Optimal Fiber Ring Deployment - A computer readable storage medium stores a set of instructions executable by a processor. The instructions are operable to receive a data set including data corresponding to a set of nodes, the data corresponding to each of the nodes including a node prize, a node cost, and a node value that is the difference between the node prize and the node cost; select one or more of the nodes for inclusion in a cluster, the cluster comprising the one or more of the nodes, two or more external links from nodes in the cluster to a network, and one or more internal links between nodes if the cluster comprises two or more nodes, each of the internal links having an internal link cost, each of the external links having an external link cost; and determine a plan for incorporating the one or more nodes in the cluster into the network, the incorporating comprising building the cluster by building the two or more external links and the one or more internal links. | 04-14-2011 |
20110207470 | TIMED FINGERPRINT LOCATING IN WIRELESS NETWORKS - Systems and techniques for determining the location of user equipment (UE) in a wireless network are disclosed. These techniques leverage geometric calculations for an overlaid bin grid framework mapping the wireless network area to store differential values for each frame of the bin grid framework for each pair of relevant NodeBs. A timing offset can be determined, such that when a time value from a target UE is accessed, the location can be quickly determined with minimal real time computation. In an aspect, the target UE time value can be search for in the pre-computed differential value data set indexed by a relevant NodeB site pair to return a set of frames (forming a hyperbola between the site pair) that can be intersected with a second set of frames for a second NodeB site pair for the same UE. The intersecting frames can represent the location of the UE in the wireless network. Further, the data can be leveraged to correct timing in the network. | 08-25-2011 |
20120082114 | METHOD AND APPARATUS FOR PLANNING RADIO FREQUENCY SPECTRUM IN A WIRELESS NETWORK - A method and apparatus for selecting a bandwidth option for a cell in a network are disclosed. For example, the method obtains, for the cell, network traffic data for a geographical area, and a physical characteristic of an antenna in the geographical area, determines busy time data traffic from the network traffic data, determines, for the cell, a cell range from the physical characteristic of the antenna, selects a bandwidth option from a plurality of bandwidth options, and determines an average throughput in accordance with the bandwidth option that is selected and the cell range. | 04-05-2012 |
20120134294 | METHOD AND APPARATUS FOR PLANNING RADIO NETWORK CONTROLLERS IN A WIRELESS NETWORK - A method and apparatus for providing planning of a plurality of radio network controllers in a wireless network are disclosed. For example, the method obtains input data, and determines a limit for at least one radio network controller parameter in accordance with the input data. The method determines if the limit for the at least one radio network controller parameter is exceeded and determines an optimal output for an objective function, wherein the objective function is based on a plurality of penalty factors, if the limit for the at least one radio controller parameter is exceeded. | 05-31-2012 |
20120140627 | METHOD AND APPARATUS FOR PLANNING SERVING GENERAL PACKET RADIO SERVICE SUPPORT NODES IN A WIRELESS NETWORK - A method and apparatus for providing planning of a plurality of serving general packet radio service support nodes in a wireless network are disclosed. For example, the method obtains input data, and determines a limit for at least one serving general packet radio service support node parameter in accordance with the input data. The method determines if the limit for the at least one serving general packet radio service support node parameter is exceeded and determines an optimal output for an objective function, wherein the objective function is based on a plurality of penalty factors, if the limit for the at least one serving general packet radio service support node parameter is exceeded. | 06-07-2012 |
20120140674 | METHOD AND APPARATUS FOR PLANNING BASE STATION CONTROLLERS IN A WIRELESS NETWORK - A method and apparatus for providing planning of a plurality of base station controllers in a wireless network are disclosed. For example, the method obtains input data, and determines a limit for at least one base station controller parameter in accordance with the input data. The method determines if the limit for the at least one base station controller parameter is exceeded and determines an optimal output for an objective function, wherein the objective function is based on a plurality of penalty factors, if the limit for the at least one base station controller parameter is exceeded. | 06-07-2012 |
20120142360 | METHOD AND APPARATUS FOR PLANNING MOBILE SWITCHING CENTERS IN A WIRELESS NETWORK - A method and apparatus for providing planning of a plurality of mobile switching centers in a wireless network are disclosed. For example, the method obtains input data, and determines a limit for at least one mobile switching center parameter in accordance with the input data. The method determines if the limit for the at least one mobile switching center parameter is exceeded and determines an optimal output for an objective function, wherein the objective function is based on a plurality of penalty factors, if the limit for the at least one mobile switching center parameter is exceeded. | 06-07-2012 |
20120147782 | METHOD AND APPARATUS FOR OPTIMAL INTERCONNECTION OF TELECOMMUNICATION NODES VIA A RELIABLE MICROWAVE CLUSTERING - A method and apparatus for providing a topology for interconnection of telecommunication nodes in a communication network are disclosed. For example, the method obtains input data, and determines values of: at least one set, at least one parameter, and at least one variable associated with the communication network in accordance with the input data. The method then determines the topology for the interconnection via microwave links of the telecommunication nodes from an objective function in accordance with the at least one set, at least one parameter, and at least one variable, wherein the objective function is based on a plurality of penalty factors. | 06-14-2012 |
20120252489 | TIMED FINGERPRINT LOCATING IN WIRELESS NETWORKS - Systems and techniques for determining the location of user equipment (UE) in a wireless network are disclosed. These techniques leverage geometric calculations for an overlaid bin grid framework mapping the wireless network area to store differential values for each frame of the bin grid framework for each pair of relevant NodeBs. A timing offset can be determined, such that when a time value from a target UE is accessed, the location can be quickly determined with minimal real time computation. In an aspect, the target UE time value can be search for in the pre-computed differential value data set indexed by a relevant NodeB site pair to return a set of frames (forming a hyperbola between the site pair) that can be intersected with a second set of frames for a second NodeB site pair for the same UE. The intersecting frames can represent the location of the UE in the wireless network. Further, the data can be leveraged to correct timing in the network. | 10-04-2012 |
20130109398 | METHOD AND APPARATUS FOR PLANNING MOBILE SWITCHING CENTERS IN A WIRELESS NETWORK | 05-02-2013 |
20130288711 | TIMED FINGERPRINT LOCATING IN WIRELESS NETWORKS - A location of user equipment (UE) in a wireless network is determined. Geometric calculations are leveraged for an overlaid bin grid framework mapping the wireless network area to store differential values for each frame of the bin grid framework for each pair of relevant NodeBs. A timing offset can be determined, such that when a time value from a target UE is accessed, the location can be quickly determined. The target UE time value can be searched for in the pre-computed differential value data set indexed by a relevant NodeB site pair to return a set of frames (forming a hyperbola between the site pair) that can be intersected with a second set of frames for a second NodeB site pair for the same UE. The intersecting frames can represent the location of the UE in the wireless network and timing in the network is correctable based on the data. | 10-31-2013 |
20140029521 | CODE PLANNING FOR WIRELESS COMMUNICATIONS - Scrambling code conflicts can be mitigated by primary scrambling code reuse that minimizing a potential interference Primary scrambling codes are applied to a first set of cells located in a portion of the network being considered. A second set of cells are evaluated for primary scrambling code reuse based on a distance parameter and/or a coverage area. If the distance parameter is greater than a defined distance, primary scrambling code reuse can be applied. If all distance parameters evaluated are less than the distance parameter, a length of the distance parameter is reduced and the distance between cells is reevaluated. | 01-30-2014 |
20140141788 | METRO CELL PLANNING - Dynamic metro cell location planning is provided within the wireless communication coverage area of a macro cell. Metro cell location planning can include obtaining performance parameters associated with the macro cell and evaluating coverage parameters of the macro cell. Metro cell location planning can also include selecting, based on the performance parameters and the coverage parameters, a location within a wireless communication coverage area of the macro cell for placement of the metro cell. The selected location can be conveyed to a user and/or entity for deployment of the metro cells. Metro cells can be used by a carrier to fill a coverage hole and/or to offload capacity hot-spots within the network. | 05-22-2014 |
20140148144 | METHOD AND APPARATUS FOR PLANNING BASE STATION CONTROLLERS IN A WIRELESS NETWORK - A method and apparatus for providing planning of a plurality of base station controllers in a wireless network are disclosed. For example, the method obtains input data, and determines a limit for at least one base station controller parameter in accordance with the input data. The method determines if the limit for the at least one base station controller parameter is exceeded and determines an optimal output for an objective function, wherein the objective function is based on a plurality of penalty factors, if the limit for the at least one base station controller parameter is exceeded. | 05-29-2014 |
20140257987 | METHOD AND SYSTEM FOR A PERSONALIZED CONTENT DISSEMINATION PLATFORM - The disclosure provides a method and corresponding system for personalizing and disbursing content material in an automated fashion based on differing characteristics or profiles of the recipients. The system includes a database of potential recipients with key characteristics such as location data, revenue, product ownership, customer status, tenure with the company/organization, payment status, credit rating, whether they have recently responded to other material, and the like. Dissemination media include email communications, collaterals, brochures, textual materials, image and video information, and any similar media, where the contents of the communication material is customized based on the key characteristics profiles of the recipients and driven by a set of business rules that can be adapted to fit various scenarios. | 09-11-2014 |
20140378153 | METHOD AND APPARATUS FOR PLANNING RADIO FREQUENCY SPECTRUM IN A WIRELESS NETWORK - A method and apparatus for selecting a bandwidth option for a cell in a network are disclosed. For example, the method obtains, for the cell, network traffic data for a geographical area, and a physical characteristic of an antenna in the geographical area, determines busy time data traffic from the network traffic data, determines, for the cell, a cell range from the physical characteristic of the antenna, selects a bandwidth option from a plurality of bandwidth options, and determines an average throughput in accordance with the bandwidth option that is selected and the cell range. | 12-25-2014 |
20150146566 | METHOD AND APPARATUS FOR TRACKING AREA PLANNING AND OPTIMIZATION IN A WIRELESS NETWORK - A method, computer-readable storage device and an apparatus for planning tracking areas in a wireless network are disclosed. For example, the method represents geographical neighbor relations between each pair of base stations in a first set, and represents in a third set a plurality of potential assignment options for each base station of the first set to tracking areas in a second set, represents the historical data on paging traffic among the base stations in the first set via a first parameter, and represents the historical data on tracking area update traffic among the tracking areas of the second set via a second parameter, and determines for each base station in the first set, the optimal assignment of a tracking area in the second set. | 05-28-2015 |
20150148059 | TIME DISTANCE OF ARRIVAL BASED MOBILE DEVICE LOCATION DETECTION WITH DISTURBANCE SCRUTINY - Techniques for locating a mobile device using a time distance of arrival (TDOA) method with disturbance scrutiny are provided. In an aspect, for respective combinations of three base station devices of a number of base station devices greater than or equal to three, intersections in hyperbolic curves, generated using a closed form function with input values based on differences of distances from the device to pairs of base station devices of the respective combinations of three base station devices, are determined. The intersection points are then tested for robustness against measurement errors associated with the input values and a subset of the intersection points that are associated with a degree of resistance to the measurement errors are selected to estimate a location of the device. | 05-28-2015 |
Wenjun Zhao, Montgomery, NJ US
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20140105896 | FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN - The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the proteins. | 04-17-2014 |
20140107020 | FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN - The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the proteins. | 04-17-2014 |
20140309163 | FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN - The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the proteins. | 10-16-2014 |
20150072919 | FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN - The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the proteins. | 03-12-2015 |
20150231211 | FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN - The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the proteins. | 08-20-2015 |
Wenyi Zhao, Monroe Township, NJ US
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20140135320 | HETEROARYL DERIVATIVES AND USES THEREOF - The present invention relates to antimalarial compounds and their use against protozoa of the genus | 05-15-2014 |
20140135360 | Aryl Derivatives And Uses Thereof - The present invention relates to antimalarial compounds and their use against protozoa of the genus | 05-15-2014 |
20150080324 | Aryl Derivatives And Uses Thereof - The present invention relates to antimalarial compounds and their use against protozoa of the genus | 03-19-2015 |
Xianfeng Zhao, Harrison, NJ US
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20130215439 | Systems and Methods for Facilitating Reproduction of Arbitrary Colors - Systems and methods are provided for facilitating reproduction of arbitrary colors in a workflow by identifying color reproduction processes in the workflow and characterizing the color reproduction processes by determining a statistical variance (e.g., as characterized by a probability density function). Systems and methods are provided for simulating possible output colors for a color reproduction process that involve identifying a desired color for reproduction and determining possible output colors for the color reproduction process based on a predetermined statistical variance. Systems and methods are provided for mapping out-of-gamut-colors for a color reproduction process are provided that involve providing an out-of-gamut color, consulting a database of characterized artistic adjustments, selecting a first adjusted color by applying an artistic adjustment from the database to the out-of gamut color, determining if the first adjusted color is out-of-gamut, and, if out-of-gamut, selecting a second adjusted color by adjusting a magnitude of the vector. | 08-22-2013 |
Xilin Zhao, Livingston, NJ US
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20130133650 | GAS-BASED TREATMENT FOR INFECTIVE DISEASE - A gas mixture for treatment of a mycobacterial infection and methods thereof, wherein the gas mixture comprises hydrogen. In certain applications, the gas mixture further comprises oxygen and optionally an inert or anaerobic gas, preferably selected from the group consisting of nitrogen, helium, argon, carbon dioxide, and mixtures thereof. The methods for treatment comprise direct inhalation of the gas mixture comprising hydrogen and oxygen, intubation of a patient with a double lumen endotracheal tube thereby supplying one lung with an anaerobic gas, and administration of a gas mixture comprising hydrogen and oxygen in a hyperbaric setting. Also provided is a method of sterilization of a | 05-30-2013 |
Yangbing Zhao, Lumberton, NJ US
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20150322169 | Enhancing Activity of CAR T Cells by Co-Introducing a Bispecific Antibody - The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a T cell, genetically modified to express a chimeric antigen receptor (CAR), a bispecific antibody, or a combination thereof to a subject. The CAR and bispecific antibody of the invention can comprise a human antibody, a humanized antibody, or antigen-binding fragments thereof. | 11-12-2015 |
Yangbing Zhao, Cherry Hill, NJ US
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20140219975 | SWITCH COSTIMULATORY RECEPTORS - The present invention relates generally to a fusion protein that when displayed on a cell can convert a negative signal into a positive signal in the cell. The fusion protein is a chimeric protein in that the protein comprises at least two domains, wherein the first domain is a polypeptide that is associated with a negative signal and the second domain is a polypeptide that is associated with a positive signal. Thus, the invention encompasses switch receptors that are able to switch negative signals to positive signals for enhancement of an immune response. | 08-07-2014 |
20150017141 | USE OF ICOS-BASED CARS TO ENHANCE ANTITUMOR ACTIVITY AND CAR PERSISTENCE - The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a genetically modified Th17 cell to express a CAR having an antigen binding domain, a transmembrane domain, and an ICOS intracellular signaling domain. | 01-15-2015 |
20150024482 | Compositions and Methods for Generating a Persisting Population of T Cells Useful for the Treatment of Cancer - The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain, wherein the T cell exhibits prolonged exponential expansion in culture that is ligand independent and independent of the addition of exogenous cytokines or feeder cells. | 01-22-2015 |
Yifang Zhao, Randolph, NJ US
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20160068439 | MOLDABLE ENGINEERED STONE - This invention provides a moldable engineered stone composition comprising an ethylenically unsaturated acrylic polymer capable of being covalently crosslinked, a mineral particulate, and an ionic crosslinking agent which forms ionic bonds within the syrup of unsaturated acrylic polymer via unreacted acid groups, causing thickening prior to curing and prior to the formation of covalent bonds via the double bonds of the polymer chain. The composition is then capable of being extruded and molded in a press. Articles formed by curing the composition and methods for producing the composition are also disclosed. | 03-10-2016 |
Ying Zhao, Mahwah, NJ US
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20120150128 | PEN NEEDLE ASSEMBLY WITH DIFFERENT GAUGE NEEDLE CANNULAS - A pen needle assembly is provided herein which includes: a hub having a body with a transverse wall; an arrangement, disposed on the hub proximally of the transverse wall, for mounting the hub onto an injector; a first needle cannula extending distally from the transverse wall, the first needle cannula terminating at a distal end, formed for insertion into a patient, with a first lumen extending proximally from the distal end, the first needle cannula being of a first gauge; and, a second needle cannula extending proximally from the transverse wall, the second needle cannula extending from a distal end and terminating at a proximal end with a second lumen extending distally from the proximal end. The first and second lumens are in communication. Further, the second needle cannula is of a second gauge, the second gauge defining a larger external cross-section than the first gauge. Advantageously, with the subject invention, two needle cannulas may be arranged in series of different gauges. This permits use of a thinner gauge needle cannula for injection into a patient with a larger gauge, more rigid, needle cannula being provided for accessing a drug cartridge or other reservoir. | 06-14-2012 |
Yuanyuan Zhao, Edison, NJ US
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20140136575 | LOG-STRUCTURED GARBAGE COLLECTION - System and method for log-structured garbage collection are provided. In particular, some embodiments use write pointer to read pointer offsets to enable reclamation of space within a log-structured storage medium (e.g., sequential forward only write mechanisms such as SSD, Tape, Shingled Drives, Flash Drives, etc.). These techniques allow the garbage collection system to reclaim space without copying data from one storage medium to another. Instead of copying the data, various embodiments reset the write and read pointers. In addition, different retention policies can be easily enforced while allowing for efficient garbage collection. For example, in a backup storage, each log-structured media can be designated with a retention time and only allow workloads with the specified retention time to be stored. As a result, the garbage collection incurs only read pointer movements. | 05-15-2014 |
Yufen Zhao, Pennington, NJ US
Patent application number | Description | Published |
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20090048244 | PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of formula I | 02-19-2009 |
20100113458 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) | 05-06-2010 |
20100323994 | SUBSTITUTED IMIDAZOPYRIDAZINES USEFUL AS KINASE INHIBITORS - The invention provides compounds of formula I | 12-23-2010 |
20100331324 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION - Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at least one androgen receptor-associated condition, such as, for example, cancer, and pharmaceutical compositions comprising such compounds. | 12-30-2010 |
20110039838 | PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of formula I | 02-17-2011 |
20120283241 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) | 11-08-2012 |
20140018319 | IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) | 01-16-2014 |
20140087992 | BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS AND PRODRUGS THEREOF - Disclosed are compounds of Formula (I) and/or salts thereof: | 03-27-2014 |
20140179674 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) | 06-26-2014 |
20140256700 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS - The present invention is directed to carbazole compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders. | 09-11-2014 |
20150065465 | IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) | 03-05-2015 |
20150210697 | IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS - The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazotriazines inhibit protein kinase activity thereby making them useful as anticancer agents. | 07-30-2015 |
20150231152 | FLUOROALKYL AND FLUOROCYCLOALKYL 1,4-BENZODIAZEPINONE COMPOUNDS - Disclosed are compounds of Formula (I): (Formula (I)) wherein: R | 08-20-2015 |
20150239851 | ALKYL, FLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS - Disclosed are compounds of Formula (I) and/or salts thereof: (I) wherein: R | 08-27-2015 |
Zhengxue John Zhao, Marlboro, NJ US
Patent application number | Description | Published |
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20100226285 | NETWORK DESIGN METHOD - A network design method for Ethernet-type networks exhibiting capacities sufficient for operation during normal periods as well those as periods when a single node or link has failed. | 09-09-2010 |
Zhicheng Zhao, Bridgewater, NJ US
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20120142735 | DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]- 1H-INDOL-3-YL]-METHANONES - The present invention extends to a compound of formula I: | 06-07-2012 |
20120245161 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS - The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of the formula | 09-27-2012 |
20120245199 | [4 [4-(AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-(1H-PYRROLO-PYRIDIN-YL- )-METHANONES AND SYNTHESIS THEREOF - The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase. | 09-27-2012 |
20130005728 | SUBSTITUTED PYRIMIDINES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS - The present invention is directed to a substituted pyrimidine compound of formula (I) | 01-03-2013 |
20130005741 | SUBSTITUTED PYRIMIDINE AS A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST - The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I): | 01-03-2013 |
Zhiqiang Zhao, Rahway, NJ US
Patent application number | Description | Published |
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20150105317 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES - Insulin conjugates comprising an insulin molecule covalently attached to at least one bi-dentate linker having two arms, each arm independently attached to a ligand comprising a saccharide and wherein the saccharide for at least one ligand of the linker is fucose are disclosed. The insulin conjugates display a pharmacokinetic (PK) and/or pharmacodynamic (PD) profile that is responsive to the systemic concentrations of a saccharide such as glucose or alpha-methylmannose even when administered to a subject in need thereof in the absence of an exogenous multivalent saccharide-binding molecule such as Con A. | 04-16-2015 |
Zhiqiang Zhao, Scotch Plains, NJ US
Patent application number | Description | Published |
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20100087425 | Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors - This invention discloses novel gamma secretase inhibitors of the formula: | 04-08-2010 |
20100093695 | Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors - This invention discloses novel gamma secretase inhibitors of the formula: | 04-15-2010 |
20100247514 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 09-30-2010 |
20110015190 | GAMMA SECRETASE MODULATORS - This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R | 01-20-2011 |
20110027264 | GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula: Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I). | 02-03-2011 |
20110236400 | TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS - Disclosed are novel gamma secretase inhibitors of the formula. Also disclosed are methods of inhibiting gamma-secretase, methods of treating neurodegenerative diseases, and methods of treating Alzheimer's Disease. Also disclosed are processes for preparing alkenes in one reaction step using a mixture of an aldehyde (or ketone) and an alkyl substituted with two electron withdrawing groups, and reacting the mixture with: (a) a sulfonyl halide (e.g., a sulfonyl chloride) and a basic tertiary amine, or, (b) a sulfonyl anhydride and a basic amine, or (c) an aryl-C(O)-halide and a basic tertiary amine, or (d) an aryl-C(O)—O—C(O)-aryl and a basic tertiary amine, or (e) an heteroaryl-C(O)-halide and a basic tertiary amine, or (f) a heteroaryl-C(O)—O—C(O)-heteroaryl and a basic tertiary amine. | 09-29-2011 |
20110257156 | GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides novel heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions. | 10-20-2011 |
20120264736 | BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS - This invention discloses novel gamma secretase inhibitors of the formula: | 10-18-2012 |
20130261140 | TRICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS - The present invention is directed to novel tricyclic heterocycles of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. I | 10-03-2013 |
20140296311 | GAMMA SECRETASE MODULATORS - Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing compounds of Formula (I) and use of the compounds in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease. | 10-02-2014 |
20150307533 | SPIROCYCLIC SULFONES AS GAMMA SECRETASE INHIBITORS - Disclosed herein are compounds of Formula (I), wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and use of the compound in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease. | 10-29-2015 |
Zhi Qiang Zhao, Bridgewater, NJ US
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20090300750 | Proxy Based Two-Way Web-Service Router Gateway - A system for providing two-way Web services is disclosed that enables the client and server to be in different enterprise domains—behind firewalls—with few or no changes to the firewalls. In accordance with the illustrative embodiment, a “tunnel hub” is deployed in the public domain and “tunnel gateways” are deployed behind the firewalls where the clients request two-way services and the servers provide two-way services. Each tunnel gateway initiates a secure tunnel out through the firewall to the target hub. Thereafter, a request for service enters the tunnel gateway, travels to the tunnel hub and to the appropriate tunnel gateway where the server is that provides the service. When the server provides the service, it enters the tunnel gateway, travels to the tunnel hub and to the appropriate tunnel gateway where the client is that requested the service. | 12-03-2009 |
20110078781 | Framework for Communicating Across a Firewall - A system for enabling communication between a first domain and a second domain is disclosed. At least the first domain is protected by a firewall. A first data-processing system is provided in the first domain and a second data-processing system provided in second domain. The second domain hosts an application that the first domain desires to access. To enable the communication between the two domains a tunnel is established through the firewall. The tunnel runs from the first data-processing system to the second data-processing system. The second data-processing system provides a web-proxy interface to interface to the application and also acts as a tunnel gateway. | 03-31-2011 |
20110208908 | METHOD AND APPARATUS FOR HIGH AVAILABILITY (HA) PROTECTION OF A RUNNING VIRTUAL MACHINE (VM) - High availability (HA) protection is provided for an executing virtual machine. A standby server provides a disk buffer that stores disk writes associated with a virtual machine executing on an active server. At a checkpoint in the HA process, the active server suspends the virtual machine; the standby server creates a checkpoint barrier at the last disk write received in the disk buffer; and the active server copies dirty memory pages to a buffer. After the completion of these steps, the active server resumes execution of the virtual machine; the buffered dirty memory pages are sent to and stored by the standby server. Then, the standby server flushes the disk writes up to the checkpoint barrier into disk storage and writes newly received disk writes into the disk buffer after the checkpoint barrier. | 08-25-2011 |
20120084520 | Method and Apparatus for Efficient Memory Replication for High Availability (HA) Protection of a Virtual Machine (VM) - High availability (HA) protection is provided for an executing virtual machine. At a checkpoint in the HA process, the active server suspends the virtual machine; and the active server copies dirty memory pages to a buffer. During the suspension of the virtual machine on the active host server, dirty memory pages are copied to a ring buffer. A copy process copies the dirty pages to a first location in the buffer. At a predetermined benchmark or threshold, a transmission process can begin. The transmission process can read data out of the buffer at a second location to send to the standby host. Both the copy and transmission processes can operate asynchronously on the ring buffer. The ring buffer cannot overflow because the transmission process continues to empty the ring buffer as the copy process continues. This arrangement allows for using smaller buffers and prevents buffer overflows, and thereby, it reduces the VM suspension time and improves the system efficiency. | 04-05-2012 |
20120084782 | Method and Apparatus for Efficient Memory Replication for High Availability (HA) Protection of a Virtual Machine (VM) - High availability (HA) protection is provided for an executing virtual machine. At a checkpoint in the HA process, the active server suspends the virtual machine; and the active server copies dirty memory pages to a buffer. During the suspension of the virtual machine on the active host server, dirty memory pages are copied to a ring buffer. A copy process copies the dirty pages to a first location in the buffer. At a predetermined benchmark or threshold, a transmission process can begin. The transmission process can read data out of the buffer at a second location to send to the standby host. Both the copy and transmission processes can operate substantially simultaneously on the ring buffer. As such, the ring buffer cannot overflow because the transmission process continues to empty the ring buffer as the copy process continues. This arrangement allows for smaller buffers and prevents buffer overflows. | 04-05-2012 |
Zhixiang Jason Zhao, Plainsboro, NJ US
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20130140177 | TESTING CARTRIDGE FOR AN IN VITRO MEDICAL DIAGNOSTIC DEVICE - The present disclosure relates to a removable assay cartridge containing a polymer body with channels for fluid movement for an in vitro medical diagnostic device. The device also includes a removable calibration fluid cartridge. | 06-06-2013 |
20130140179 | IN VITRO MEDICAL DIAGNOSTIC DEVICE AND SYSTEM - The present disclosure relates to an in vitro medical diagnostic device that includes a removable calibration fluid cartridge. The device also includes a removable assay cartridge containing a polymer body with channels for fluid movement. | 06-06-2013 |
20130142709 | CALIBRATION FLUID CARTRIDGE FOR AN IN VITRO MEDICAL DIAGNOSTIC DEVICE - The present disclosure relates to a calibration cartridge for an in vitro medical diagnostic device. The device also includes a removable assay cartridge containing a polymer body with channels for fluid movement. | 06-06-2013 |