Weiss, CA
Adam Weiss, Toronto CA
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20160062101 | METHOD AND APPARATUS FOR SMALL AND LARGE FORMAT HISTOLOGY SAMPLE EXAMINATION - The disclosure is directed at a method and apparatus for small and large format histology examination. By providing a pair of networked processors and by linking one processor with a microscope, control of the microscope may be performed at a remote location. Further, by transmitting low magnification images, a reviewer may determining a region of interest before having a higher magnification image captured thereby reducing the data storage required for this histology examination. | 03-03-2016 |
Alonzo Weiss, Tofield CA
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20110024473 | CARGO BED EXTENSION - An adjustable cargo support apparatus for use with vehicles having a hitch receiver socket includes an elongated arm engageable at one end thereof inside such hitch receiver socket, a dual sleeve member, a tee-shaped cargo support beam having a riser slidingly engageable inside one of the open-ended sleeves of the dual sleeve member, and at least one releasable position locking means for restraining movement of the sleeve relative to the elongated arm. The dual sleeve beam member further includes an elongated connecting beam, a first open-ended sleeve having a portion of a side wall fixedly attached to one end of the connecting beam at a predetermined angle, and a second open-ended sleeve fixedly attached at an opposing end of the connecting beam, wherein an axis of the second sleeve is substantially perpendicular to that of the first sleeve. | 02-03-2011 |
Andrew Weiss, Winnipeg CA
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20120264211 | CRYOPRESERVATION OF ARTICULAR CARTILAGE - The invention relates generally to methods and compositions for the cryopreservation and/or vitrification of tissue including articular cartilage and the preparation of said tissue for clinical or research use, including but not limited to joint replacement and the treatment and prevention of osteoarthritis. | 10-18-2012 |
20150150239 | CRYOPRESERVATION OF ARTICULAR CARTILAGE - The invention relates generally to methods and compositions for the cryopreservation and/or vitrification of tissue including articular cartilage and the preparation of said tissue for clinical or research use, including but not limited to joint replacement and the treatment and prevention of osteoarthritis. | 06-04-2015 |
Andrew E. Weiss, Toronto CA
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20140165933 | DUCT FOR ENGINE BAY COOLING AND VENTILATION - An air cooling system provides cooling air within an engine bay of a vehicle. The vehicle includes a radiator and a cooling fan, the cooling fan is operable to force air to flow through the radiator, and the cooling fan is also operable to blow air within a blow zone away from the cooling fan and into the engine bay. The air cooling system includes a duct having a first end that defines an inlet, a second end that defines an outlet, and a sidewall that extends between the first end and the second end. The duct is operable to be mounted to the vehicle with the second end and the outlet disposed within the downstream blow zone such that air exiting the outlet is blown by the cooling fan toward the engine bay. | 06-19-2014 |
Eric Weiss, Oakville CA
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20090098816 | AIR-HANDLING DEVICE - A method for handling air when distributing air inside an elongated vehicle includes supplying air to a roof air duct ( | 04-16-2009 |
Jason Weiss, Edmonton CA
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20100037697 | PRESSURE SENSOR - An apparatus for sensing pressure is provided comprising a housing, electronics, a pressure sensor and a secondary seal. The housing comprises an interior bore and a first end, with the interior bore forming an opening at the first end. The electronics may be disposed in the interior bore. The pressure sensor is mounted at the first end of the interior bore. The pressure sensor may be operatively connected to send signals to the electronics in response to external fluid pressure. The pressure sensor may, at least in part, form a primary seal at the first end of the interior bore. The secondary seal may be disposed in the interior bore in between the pressure sensor and the electronics. The secondary seal may be configured to act as a backup seal to the primary seal. The secondary seal provides an added degree of safety from high pressure pipeline contents. The secondary seal also ensures that the important interior electrical components of the apparatus are not damaged upon failure of any component located at the first end. If the pressure sensor or primary seal is damaged, for example, a new pressure sensor or primary seal may be installed without having to replace the entire apparatus. The secondary seal also prevents fluid from a high pressure pipeline that has compromised the primary seal from being ejected from the pipeline. The secondary seal also prevents pipeline media from migrating through the electrical cable to a non-hazardous location. | 02-18-2010 |
Marvin Weiss, Calgary CA
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20130153672 | APPARATUS AND METHODS FOR CONVEYING A FLOW OF OIL-CONTAINING LIQUID INTO AN OIL SEPARATION SKIM TANK, AND SKIM TANKS INCLUDING THE SAME - Apparatus and methods for conveying a flow of oil-containing liquid into an oil separation skim tank, and a skim tank incorporating such apparatus and methods, are disclosed. One such apparatus includes at least one diffuser, the diffuser defining an intake opening configured to receive the flow of oil-containing liquid and an exhaust opening configured to convey the flow of oil-containing liquid into the skim tank. The diffuser is configured to cause the flow of oil-containing liquid to have a greater horizontal width at the exhaust opening than at the intake opening, while minimizing vertical divergence of the flow at the exhaust opening. | 06-20-2013 |
20150299005 | ACHIEVING WATER RELEASE ZONE FOR DEWATERING THICK FINE TAILINGS BASED ON SHEARING PARAMETER SUCH AS CAMP NUMBER - Various techniques are provided in relation to flocculation and/or dewatering of thick fine tailings, with shear conditioning of flocculated tailings material in accordance with a pre-determined shearing parameter, such as the Camp Number. One example method of treating thick fine tailings including dispersing a flocculant into the thick fine tailings to form a flocculating mixture; shearing the flocculating mixture to increase yield stress and produce a flocculated mixture; shear conditioning the flocculated mixture to decrease the yield stress and break down flocs, the shear conditioning being performed in accordance with the pre-determined shearing parameter to produce conditioned flocculated material within a water release zone where release water separates from the conditioned flocculated material. The conditioned flocculated material can then be subjected to dewatering, for example by depositing, thickening or filtering. The design, construction and/or operation of a flocculation pipeline assembly can be facilitated. | 10-22-2015 |
Marvin Harvey Weiss, Calgary CA
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20120175315 | Process for Flocculating and Dewatering Oil Sand Mature Fine Tailings - A process for dewatering oil sand fine tailings is provided and comprises a dispersion and floc build-up stage comprising in-line addition of a flocculent solution comprising an effective amount of flocculation reagent into a flow of the oil sand fine tailings; a gel stage wherein flocculated oil sand fine tailings is transported in-line and subjected to shear conditioning; a floc breakdown and water release stage wherein the flocculated oil sand fine tailings releases water and decreases in yield shear stress, while avoiding an oversheared zone; depositing the flocculated oil sand fine tailings onto a deposition area to form a deposit and to enable the release water to flow away from the deposit, preferably done in a pipeline reactor and managing shear according to yield stress and CST information and achieves enhanced dewatering. | 07-12-2012 |
20130043165 | Process for Drying Oil Sand Mature Fine Tailings - A process for drying fine tailings is provided. The process, which may use a pipeline reactor system, comprises providing an in-line flow of the fine tailings; continuously introducing a flocculent solution to cause dispersion and commence flocculation of the fine tailings and may comprise rapid turbulent mixing; subjecting the fine tailings to flocculation and water release conditioning in-line to cause formation and rearrangement of floes and increasing the yield shear stress to form flocculated fine tailings while avoiding over-shearing of the flocs; and depositing the fine tailings to allow the release of water, formation of a non-flowing fine tailings deposit and drying of the non-flowing fine tailings deposit. The process enables effective in-line dispersion, flocculation and water release, resulting in reliable deposition and drying of the fine tailings deposit. | 02-21-2013 |
20130081298 | Depositing and Farming Methods for Drying Oil Sand Mature Fine Tailings - Methods for drying oil sand fine tailings treated to comprise flocculated fine tailings, by deposition and farming techniques, are provided. A deposition cell is provided with a sloped bottom surface and the flocculated fine tailings are deposited to undergo channelless advancement in the cell while allowing drainage of release water. When the deposit is uneven, the deposit may be plowed while wet for spreading and ensuring water release conditioning is imparted thereto, while avoiding over-shearing, and maintaining sufficient shear strength to allow standing. Once a dried upper crust forms, the deposit may be harrowed to break up the crust, expose wet regions there-beneath and create furrows in the standing deposit. The methods improve the dewatering and drying of mature fine tailings in oil sands. | 04-04-2013 |
20130233805 | Method and Device for In-Line Injection of Flocculent Agent into a Fluid Flow of Mature Fine Tailings - A method and device for in-line injecting of flocculent agent into a fluid flow of mature fine tailings (MFT). The method includes the steps of: a) providing a fluid flow of mature fine tailings to be treated along a given channel fluidly connected to the pipeline; b) providing a source of flocculating agent; and c) introducing flocculating agent inside the fluid flow of mature fine tailings via a plurality of injection outlets for injecting the flocculating agent into the fluid flow in a dispersed manner so as to increase an exposed surface area of the injected flocculating agent and thus increase a corresponding reaction with the mature fine tailings, for an improved flocculation of said mature fine tailings, and/or other desired end results. Also disclosed is a kit with corresponding components for assembling the in-line injection device to be connected in-line with the pipeline carrying the mature fine tailings to be treated. | 09-12-2013 |
Norbert Weiss, Calgary CA
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20150231203 | TREATMENT OF PAIN BY INHIBITION OF USP5 DE-UBIQUITINASE - The invention provides methods treating pain by inhibiting a Cav3.2 channel expression or function, including the use of contacting said channel in situ with an inhibitor of USP5 or an inhibitor of the interaction between Cav3.2 and USP5. | 08-20-2015 |
Samuel Weiss, Toronto CA
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20120189575 | Oligodendrocyte Production from Multipotent Neural Stem Cells - This invention relates to methods of producing oligodendrocytes from multipotent neural stem cells by using at least one oligodendrocyte promoting factor, particularly granulocyte-macrophage colony stimulating factor, granulocyte colony stimulating factor, interleukin 3 or interleukin 5. The neural stem cells may optionally be expanded prior to being subjected to the oligodendrocyte promoting factor. | 07-26-2012 |
Samuel Weiss, Calgary CA
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20090081205 | CONTINUOUS DOSING REGIMENS FOR NEURAL STEM CELL PROLIFERATING AGENTS AND NEURAL STEM CELL DIFFERENTIATING AGENTS - The present invention provides effective dosing regimes for neural stem cell proliferating agents, kits containing effective dosing regimes for neural stem cell proliferating agents, and uses thereof. In particular, neural stem cell proliferating agents, such as hCG, prolactin and EPO are delivered to mammalian subjects at low doses in a continuous fashion over several days, as opposed to delivery of high doses in a short period of time. | 03-26-2009 |
20090274668 | Combined Regulation of Neural Cell Production - This invention relates to a method of selectively producing neural cells, including neurons or glial cells, in vitro or in vivo. Also provided are methods of treating or ameliorating neurodegenerative disease or medical conditions by producing neural cells. Thus, a combination of factors is used to achieve two steps: increasing the number of neural stem cells and instructing the neural stem cells to selectively become neurons or glial cells. | 11-05-2009 |
20100113357 | Platelet-derived growth factor-responsive neural precursor cells and progeny thereof - This invention provides platelet-derived growth factor-responsive neural precursor (PRP) cells and methods of producing such cells in vivo or in vitro. These cells can further be used to generate neurons, oligodendrocytes and/or astrocytes. | 05-06-2010 |
20100135968 | Oligodendrocyte Production From Multipotent Neural Stem Cells - This invention relates to methods of producing oligodendrocytes from multipotent neural stem cells by using at least one oligodendrocyte promoting factor, particularly granulocyte-macrophage colony stimulating factor, granulocyte colony stimulating factor, interleukin 3 or interleukin 5. The neural stem cells may optionally be expanded prior to being subjected to the oligodendrocyte promoting factor. | 06-03-2010 |
20100239528 | Treating or Ameliorating a Neuroinflammatory or Demyelinating Disorder with Prolactin and Interferon-Beta - Methods, compositions and kits for treating or ameliorating a disorder associated with neuroinflammation or de-myelination in a mammal are disclosed. Said methods, compositions and kits comprise prolactin, a prolactin-inducing agent, or a variant, analog or functional fragment of prolactin in combination with interferon-β. | 09-23-2010 |
20110178009 | Pheromones and the Luteinizing Hormone for Inducing Proliferation of Neural Stem Cells and Neurogenesis - The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using a pheromone, a luteinizing hormone (LH) and/or a human chorionic gonadotrophin (hCG). The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from or suspected of having neurodegenerative diseases or conditions. | 07-21-2011 |
20110182853 | PLATELET DERIVED GROWTH FACTOR (PDGF)-DERIVED NEUROSPHERES DEFINE A NOVEL CLASS OF PROGENITOR CELLS - The present invention is related to the discovery of a novel class of neural progenitor cells, which proliferate in response to platelet derived growth factor (PDGF) and differentiate into neurons and oligodendrocytes but not astrocytes. Progeny of the progenitor cells can be obtained by culturing brain tissue in PDGF without serum, epidermal growth factor (EGF), fibroblast growth factor 2, or transforming growth factor alpha. Upon subculturing into EGF-containing media, these progeny cells can proliferate and form neurospheres, whereas PDGF has no such effect. | 07-28-2011 |
20110269681 | Prolactin Induced Increase in Neural Stem Cell Numbers - The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from neurodegenerative diseases or conditions. In addition, since neural stem cells are a source for olfactory neurons, the present invention also provides methods of increasing olfactory neurons and enhancing olfactory functions. | 11-03-2011 |
20120064028 | Pregnancy-Induced Oligodendrocyte Precursor Cell Proliferation Regulated by Prolactin - The present invention relates to a method to increase oligodendrocytes and oligodendrocyte precursor cells through administration of prolactin or a prolactin inducing agent. | 03-15-2012 |
20120244111 | Pheromones and the Luteinizing Hormone for Inducing Proliferation of Neural Stem Cells and Neurogenesis - The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using a pheromone, a luteinizing hormone (LH) and/or a human chorionic gonadotrophin (hCG). The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from or suspected of having neurodegenerative diseases or conditions. | 09-27-2012 |
20120270779 | DOSING REGIMENS FOR NEURAL STEM CELL PROLIFERATING AGENTS AND DIFFERENTIATING AGENTS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS - Effective dosing regimens for neural stem cell proliferating and differentiating agents, kits comprising effective dosing regimens for neural stem cell proliferating and differentiating agents, and uses thereof are provided herein. Such kits and methods can be utilized acutely or chronically to treat a neurodegenerative disease or condition. Furthermore, the compositions and methods can be used continuously or intermittently in various dosing regimens. | 10-25-2012 |
20120329714 | Prolactin Induced Increase in Neural Stem Cell Numbers - The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from neurodegenerative diseases or conditions. In addition, since neural stem cells are a source for olfactory neurons, the present invention also provides methods of increasing olfactory neurons and enhancing olfactory functions. | 12-27-2012 |
20150158894 | SALICYCLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF - The present invention relates to novel compounds, compositions containing same and methods for inhibiting STAT3 and/or STAT5 activity or for the treatment of a STAT3 or STAT5-dependent cancer using said compounds; or a pharmaceutically acceptable salt, solvate or prodrug thereof. | 06-11-2015 |
Walter Weiss, Kingston CA
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20150277444 | Time-Varying Extremum Seeking for Controlling Vapor Compression Systems - A method for controlling a vapor compression system determines a value of a metric of performance of the vapor compression system using a previous value of an estimated parameter and a previous value of a control signal determined for a previous time step of the control. The values of the estimated parameter represent a relationship between values of the control signal and values of the metric of performance. A current value of the estimated parameter is determined based on the previous value of the estimated parameter and an error between the determined value of the metric of performance and a measured value of the metric of performance. Next, a current value of the control signal is determined based on the current value of the estimated parameter. | 10-01-2015 |
Wenda Weiss, Munster CA
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20140186216 | APPARATUS AND METHOD FOR IDENTIFYING A HOOK EFFECT AND EXPANDING THE DYNAMIC RANGE IN POINT OF CARE IMMUNOASSAYS - The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample. The system may further include a processor configured to determine a presence of a hook effect in the immunoassay based on relative values of the first and second signals and optionally determine the target analyte concentration of the sample. | 07-03-2014 |
20140186972 | APPARATUS AND METHOD FOR IDENTIFYING A HOOK EFFECT AND EXPANDING THE DYNAMIC RANGE IN POINT OF CARE IMMUNOASSAYS - The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample. The system may further include a processor configured to determine a presence of a hook effect in the immunoassay based on relative values of the first and second signals and optionally determine the target analyte concentration of the sample. | 07-03-2014 |