Patent application number | Description | Published |
20110076214 | Reversible Room-Temperature Ionic Liquids - One aspect of the present invention relates to salts that are room-temperature ionic liquids (RTILs), methods of making them, and methods of using them in connection with temporary or permanent gas sequestration. Another aspect of the present invention relates to a class of solvents which can be transformed into RTILs by exposure to a gas, and methods of using them in connection with temporary or permanent gas sequestration. | 03-31-2011 |
20140120013 | Reversible Room-Temperature Ionic Liquids - One aspect of the present invention relates to salts that are room-temperature ionic liquids (RTILs), methods of making them, and methods of using them in connection with temporary or permanent gas sequestration. Another aspect of the present invention relates to a class of solvents which can be transformed into RTILs by exposure to a gas, and methods of using them in connection with temporary or permanent gas sequestration. | 05-01-2014 |
20150361224 | AMINO-SUBSTITUTED POLYSILOXANES COMBINED WITH POLYMERIZABLE AND UNPOLYMERIZABLE ORGANIC ACIDS - Provided is a composition comprising (i) a polysiloxane comprising a plurality of pendant amines and (ii) an acid. Also provided is a composition comprising (i) a polysiloxane comprising a plurality of pendant acids and (ii) an amine. The compositions are useful inter alia for chemical or oil spill cleanup, drug delivery systems, transparent films, adhesives, binding agents, conductors, membranes, cross-linking agents, or opticoelectronic applications. Also provided are methods for making the compositions of the invention, as well as a battery and a composition for controlled release of a compound, each comprising a composition of the invention. | 12-17-2015 |
Patent application number | Description | Published |
20100091822 | ADAPTIVE KNOWN SIGNAL CANCELLER - An adaptive known signal canceller comprising of a known signal canceller filter responsive to a known signal including a known portion of a transmitted signal, the known signal canceller filter operative to generate a filtered known signal, and a subtractor unit responsive to an input signal and operative to generate an output signal, the subtractor unit configured to subtract the filtered known signal from the input signal to generate an output signal, such that the known portion of the transmitted signal is substantially removed from the input signal. The adaptive known signal canceller further comprising of a known signal canceller update unit, responsive to a desired signal and an output signal and operative to continually adjust the coefficients of the known signal canceller filter based on the difference between the output signal and the desired signal, so that the filter coefficients substantially reflect the impulse response of a channel. | 04-15-2010 |
20100095191 | METHOD AND APPARATUS FOR DEINTERLEAVING IN A DIGITAL COMMUNICATION SYSTEM - A method and apparatus for deinterleaving in a communication system is disclosed. The method and apparatus deinterleave data units using a data deinterleaver; compressed deinterleave input symbol quality information (SQI) units using a compressed deinterleaver, wherein at least one of the input SQI units deinterleaved by the compressed deinterleaver corresponds to at least one of the plurality of data units deinterleaved by the data deinterleaver; and apply the deinterleaved SQI units to the corresponding deinterleaved data units. | 04-15-2010 |
20100177817 | SEGMENTED EQUALIZER - In one embodiment of the present invention, a segmented equalizer includes a plurality of feedforward equalizer segments, each feedforward equalizer segment responsive to delayed samples of an input signal {v | 07-15-2010 |
20120163443 | Adaptive Known Signal Canceller - An adaptive known signal canceller comprising of a known signal canceller filter responsive to a known signal including a known portion of a transmitted signal, the known signal canceller filter operative to generate a filtered known signal, and a subtractor unit responsive to an input signal and operative to generate an output signal, the subtractor unit configured to subtract the filtered known signal from the input signal to generate an output signal, such that the known portion of the transmitted signal is substantially removed from the input signal. The adaptive known signal canceller further comprising of a known signal canceller update unit, responsive to a desired signal and an output signal and operative to continually adjust the coefficients of the known signal canceller filter based on the difference between the output signal and the desired signal, so that the filter coefficients substantially reflect the impulse response of a channel. | 06-28-2012 |
Patent application number | Description | Published |
20100070317 | ARCHITECTURAL DESIGN FOR SELL FROM STOCK APPLICATION SOFTWARE - Methods, systems, and apparatus, including computer program products, for implementing a software architecture design for a software application implementing sell from stock software useful to process quotations, capture orders, process delivery and invoice. The application is structured as multiple process components interacting with each other through service interfaces, and multiple service operations, each being implemented for a respective process component. The process components include an Accounting process component; a Financial Accounting Master Data Management process component; an Outbound Delivery Processing process component; a Site Logistics Processing process component; an Inventory Processing process component; a Customer Requirement Processing process component; a Supply and Demand Matching process component; a Logistics Execution Control process component; a Due Item Processing process component; a Balance of Foreign Payment Management process component; a Payment Processing process component; a Customer Invoice Processing process component; a Customer Quote Processing process component; and a Sales Order Processing process component. | 03-18-2010 |
20100070324 | Architectural Design for Plan-Driven Procurement Application Software - Methods, systems, and apparatus, including computer program products, for implementing a software architecture design for a software application implementing plan-driven procurement. The application is structured as multiple process components interacting with each other through service interfaces, and multiple service operations, each being implemented for a respective process component. The process components include an Inbound Delivery Processing process component, a Site Logistics Processing process component, an Inventory Processing process component, a Purchase Request Processing process component, a Purchase Order Processing process component, a Purchasing Contract process component, a Supplier Invoice Processing process component, a Demand Forecast Processing process component, a Supply and Demand Matching process component, an External Procurement Trigger and Response process component, and a Logistics Execution Control process component. | 03-18-2010 |
20100070556 | Architectural Design for Data Migration Application Software - Methods, systems, and apparatus, including computer program products, for implementing a software architecture design for a software application implementing data migration. The application is structured as multiple process components interacting with each other through service interfaces, and multiple service operations, each being implemented for a respective process component. The process components include a Product Property Management process component, a Production Model Management process component, a Business Partner Data Management process component, a Product Data Maintenance process component, an Installed Base Data Management process component, a Price Master Data Management process component, an Identity Management process component, an Engineering Change Processing process component, a Migration Data Dispatching process component, and several other process components. | 03-18-2010 |
20140278626 | Consistent Interface for Task Activity Business Object - A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a task activity business object. | 09-18-2014 |
20140279413 | Consistent Interface for Phone Call Activity Business Object - A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to a phone call business object. | 09-18-2014 |
20140282081 | Consistent Interface for Email Activity Business Object - A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an email activity business object. | 09-18-2014 |
20140282082 | Consistent Interface for Appointment Activity Business Object - A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an appointment activity business object. | 09-18-2014 |
Patent application number | Description | Published |
20100039757 | BATTERY COVER LATCH MECHANISM - A battery cover latch mechanism is provided including a cover member having a pivoting assembly formed thereon, and a housing member. The housing member defines a mounting section. The pivoting assembly is configured to be either pivotably mounted within the mounting section when the cover member is rotated relative to the housing member at an angle less than 90 degrees, or detached from the mounting section when the cover member is rotated relative to the housing member at an angle equal to 90 degrees. | 02-18-2010 |
20130297677 | TERMINAL DESKTOP PROCESSING SYSTEM, TERMINAL, SERVER AND METHOD - Disclosed are a terminal desktop processing system, a terminal, a server and a method. The system includes a terminal for executing network application software and a server connected with the terminal via a network. The terminal includes a scanning module for scanning desktop layout of the application software to obtain desktop layout information of the application software; a transmission module for transmitting the desktop layout information to a server via the network; a reading module for requesting the server for desktop layout information and reading the desktop layout information correlated with the application software stored in the server; and a layout module for changing desktop layout of the application software in the terminal according to the desktop layout information. The server includes a correlation module for correlating desktop layout information with application software at the server. Usability and stability of the terminal desktop are improved. A better feeling in using the terminal desktop is provided. | 11-07-2013 |
20140365493 | DATA PROCESSING METHOD AND DEVICE - A data processing method is provided, which includes: performing a fingerprint calculation for each data element of a set of data elements to obtain fingerprint information of the data elements; grouping the data elements into data groups in accordance with the fingerprint information, including by grouping data elements with the same fingerprint information into a same data group; and selecting a particular data element from each of the data groups for modeling calculation. A corresponding device is described. With the technical solutions according to the present method, data processing amount for modeling calculation may be reduced, which may thereby reduce data processing time and improve the data processing efficiency. | 12-11-2014 |
Patent application number | Description | Published |
20090319218 | APPARATUS, METHOD AND COMPUTER-READABLE MEDIUM FOR TESTING A PANEL OF INTERFEROMETRIC MODULATORS - In some embodiments, each interferometric modulator has a stiction threshold voltage. If a voltage above the stiction threshold voltage is applied to the interferometric modulator, the interferometric modulator enters a stiction state permanently, i.e., becomes “stuck,” and the interferometric modulator becomes inoperable. Disclosed are apparatuses, methods and computer-readable media for testing a panel of interferometric modulators. A ramped voltage waveform is applied to a plurality of interferometric modulators of the panel. In response to applying the ramped voltage, the stiction threshold voltage is identified. At or above this voltage, the number of stuck interferometric modulators in the panel reaches or exceeds a first threshold number, for example, 50% of the total number of the interferometric modulators constituting the panel. The embodiments can be used to establish stiction benchmark for panel manufacturing processes, to collect data for generating statistical distribution, etc. | 12-24-2009 |
20120274666 | SYSTEM AND METHOD FOR TUNING MULTI-COLOR DISPLAYS - This disclosure provides systems, methods and apparatuses, including computer programs encoded on computer-readable storage media, for calibrating a display. In one aspect, a method of calibrating a display includes determining one or more array voltages and, based on the determined array voltages, determining one or more drive scheme voltages. The determined drive scheme voltages may include, for example, a single segment voltage applied to all of the display elements of the array, and multiple common voltages applies to multiple subsets of the display elements of the array. | 11-01-2012 |
Patent application number | Description | Published |
20110246420 | DATABASE SYSTEM BASED ON WEB APPLICATION AND DATA MANAGEMENT METHOD THEREOF - A database system based on a WEB application includes a database server ( | 10-06-2011 |
20130117555 | METHOD AND SYSTEM FOR DATA ENCRYPTION AND DECRYPTION IN DATA TRANSMISSION THROUGH THE WEB - This invention provides a method and system for data encryption and decryption in data transmission through the web. The method includes: a browser sends a cryptographic information acquisition request to a cryptographic information providing equipment; the cryptographic information providing equipment sends cryptographic information back to the browser via an HTTPS channel; the cryptographic information includes a cryptographic algorithm and a cryptographic index; the browser uses the cryptographic algorithm to encrypt the data to be transmitted, and sends the encrypted data and the cryptographic index to the web server via an HTTP channel; the web server obtains the cryptographic algorithm corresponding to the cryptographic index from the cryptographic information providing equipment, then decrypts the encrypted data. Embodiments of the present invention can alleviate the load in the HTTPS channel, and improve the overall performance. | 05-09-2013 |
20140372457 | METHOD AND DEVICE FOR PROCESSING DATA - A method and device for processing data in the field of data process are disclosed. The method includes: sorting samples according to primary keys, wherein the primary key includes a feature serial number and a sample serial number, and wherein a column value corresponding to the primary key is used as a feature value for the sample; acquiring a statistic of each feature in each category by taking the primary key and the feature value as an input key-value pair and calculating with a first algorithm model, and outputting the feature serial number and the statistic as an output key-value pair; and acquiring a contribution value of each feature to the category by performing calculation on the output key-value pair with a second algorithm model, and selecting a feature based on the contribution value. The device includes a sorting module, a first processing module and a second processing module. | 12-18-2014 |
20150178306 | METHOD AND APPARATUS FOR CLUSTERING PORTABLE EXECUTABLE FILES - The present invention relates to Internet and communication technologies, and discloses a method and apparatus for clustering portable executable (PE) files. The method comprises: extracting PE file characteristics from a PE file; generating a PE file identifier for the PE file based on the PE file characteristics; and clustering the PE file base on the PE file identifier. The apparatus comprises an extraction module, a generation module, and a clustering module. In accordance with embodiments of the present invention, a PE file identifier is generated for the PE file based on PE file characteristics extracted from the PE file, and the PE files are clustered based on the PE file identifier. Thus, random PE files are clustered into ordered classes, and the number of PE files to be processed by the antivirus clients and servers are reduced, which reduces storage costs, improves matching efficiency and the ability to detect and combat PE virus variants. | 06-25-2015 |
20150356164 | METHOD AND DEVICE FOR CLUSTERING FILE - In a method and a device for clustering files of the present application, to cluster files to be processed, information fingerprints of the files to be processed are obtained by processing information fingerprints of features of a plurality of information blocks contained in the file to be processed and are compared, and files to be processed with the same information fingerprint are taken as one cluster, so as to realize the clustering of files. The features of the information blocks in the files to be processed are identified by means of information fingerprints in this way, and then clustering is performed according to identifiers. Compared to prior art method using similarity comparisons, the method and device of the present application, which calculate and cluster an identifier of a feature, greatly reduce the data to be calculated and the degree of complexity. | 12-10-2015 |
Patent application number | Description | Published |
20120069192 | Data Processing System and Method - A data processing system and method for processing images received from multiple cameras are provided. The system includes a memory for receiving first and second images associated with respective cameras; a determiner adapted to process the first and the second images to identify respective objects depicted therein; the determiner is further adapted to calculate a predetermined metric associated with projections of the respective objects in a first frame of reference; and a labeler adapted to assign a common label to the objects according to the predetermined metric. | 03-22-2012 |
20130024551 | ENABLING CLUSTER SCALING - Embodiments of the present invention relate to methods and apparatuses for enabling cluster scaling. Specifically, there is disclosed a method of recording a context of configuration for an initial node of a cluster, comprising: retrieving at least one file to be used for configuring the initial node; and recording a context while configuring the initial node using the at least one file, the recorded context being information on the configuration of the initial node and to be used for enabling addition of a new node into the cluster. There is also disclosed a method of enabling addition of a new node into a cluster. Corresponding apparatuses are also disclosed. According to embodiments of the present invention, the efficiency of improving cluster scaling may be effectively improved. | 01-24-2013 |
20130024554 | ENABLING CLUSTER SCALING - Embodiments of the present invention relate to methods and apparatuses for enabling cluster scaling. Specifically, there is disclosed a method of recording a context of configuration for an initial node of a cluster, comprising: retrieving at least one file to be used for configuring the initial node; and recording a context while configuring the initial node using the at least one file, the recorded context being information on the configuration of the initial node and to be used for enabling addition of a new node into the cluster. There is also disclosed a method of enabling addition of a new node into a cluster. Corresponding apparatuses are also disclosed. According to embodiments of the present invention, the efficiency of improving cluster scaling may be effectively improved. | 01-24-2013 |
20130047156 | METHOD AND APPARATUS OF ASSIGNING VIRTUAL MACHINE RESOURCES - A method of sharing virtual machine resources. The method includes: in response to at least one user logging in to the virtual machine, monitoring file operations taken by the user in the virtual machine; recording the types of file operations; in response to the user logging out from the virtual machine, restoring the virtual machine back to the original state at the time when the user logged in to the virtual machine according to the recorded types of file operations; and in response to receiving a request for virtual machine resources, assigning one of the virtual machines which is idle and restored back to the original state to the requesting user. | 02-21-2013 |
20130055034 | METHOD AND APPARATUS FOR DETECTING A SUSPECT MEMORY LEAK - A method for determining a suspect memory leak, including: sampling the throughput and memory usage of an application server; based on the sampled throughput, monitoring whether the throughput decrease continually, and based on the sampled memory usage, monitoring whether the memory usage remains stable within a predefined range; in response to a continual decrease of the throughput and the memory usage remaining stable within the predetermined range, determining that the application server is suspected of having a memory leak. Using the solution of the present invention can free an administrator of the burden of artificially identifying suspect servers, can identify a suspect server during runtime and further determine whether it actually has a memory leak. | 02-28-2013 |
20130325906 | PLACING A DATABASE - A method and system for placing database. The method includes: receiving a request of creating a new database; determining whether there is a need to migrate current database among current virtual machines based on resource demand and free resource in the current virtual machines; determining database placement plan based on the resource demand, migration strategy and migration cost associated with the migration strategy in response to whether there is a need to migrate the database; and executing the database placement plan. The invention can help a database service provider to optimize database layout in database provision through database migration. | 12-05-2013 |
20140068048 | MANAGING REMOTE DEVICES - A method and apparatus for managing remote devices. In one embodiment of the present invention, there is provided a method of managing a remote device, comprising: obtaining a first identifier based on a name sequence in state information of the remote device, the first identifier being for indicating a template that provides the state information; obtaining a second identifier based on a numerical value sequence in the state information; sending a state access notification that comprises at least the first identifier and the second identifier; and providing the state information based on the first identifier and the second identifier in response to having received a result of activating the state access notification. In one embodiment of the present invention, there is provided an apparatus for managing a remote device. | 03-06-2014 |
Patent application number | Description | Published |
20120124937 | HYBRID FRP-CONCRETE-STEEL DOUBLE-SKIN TUBULAR BEAMS AND HYBRID DSTB/SLAB UNITS USING THE BEAMS - This invention relates to a novel hybrid FRP-concrete-steel double-skin tubular beam and a hybrid beam/slab unit which employs the hybrid tubular beam. The hybrid double-skin tubular beam consists of an outer FRP tube, an inner steel tube, and concrete filled between the outer FRP tube and the inner steel tube, and the inner steel tube is provided with a plurality of shear connectors on its side engaged with concrete. The inner steel tube is located eccentrically relative to the outer FRP tube towards the side of the hybrid tubular beam to be tensed. The inventive hybrid beam/slab unit is a slab-on-girder system which is comprised of the hybrid double-skin tubular beam and the lightweight slab of good corrosion resistance (such as a FRP slab or an aluminum slab) that is provided thereon, or a deck or floor system which is comprised of the hybrid double-skin tubular beam and a FRP-rib reinforced concrete slab and in which the upper portion of the hybrid double-skin tubular beam is engaged with the bottom of the FRP-rib reinforced concrete slab thereinside so as to form an integrated body. The inventive hybrid tubular beam features an excellent resistance against corrosion, a good ductility and cost-effectiveness. and is lightweight, while at the same time allows for easy construction and connection with other members. | 05-24-2012 |
20150199226 | Recommending a Suspicious Component in Problem Diagnosis for a Cloud Application - The present invention discloses a method and an apparatus for recommending a suspicious component in problem diagnosis for a cloud application. In the method, firstly a graph data model representing a hierarchical structure of the cloud application is constructed, wherein the graph data model comprises an application node representing the cloud application, a plurality of component nodes representing a plurality of components of the cloud application, and inter-node lines indicating inter-node relationships. Then real-time information of the cloud application is obtained, in response to detecting performance degradation of the cloud application. Impact degrees of the plurality of component nodes on the performance degradation of the cloud application is obtained based on the constructed graph data model and the obtained real-time information, and a suspicious component sequence is generated according to the impact degrees of the plurality of component nodes. | 07-16-2015 |
Patent application number | Description | Published |
20140119568 | Adaptive Microphone Beamforming - The present invention relates to adaptive beamforming in audio systems. More specifically, aspects of the invention relate to a method for adaptively estimating a target sound signal by establishing a simulation model simulating an audio environment comprising: a plurality of spatially separated microphones, a target sound source, and a number of audio noise sources. | 05-01-2014 |
20140270219 | METHOD, APPARATUS, AND MANUFACTURE FOR BEAMFORMING WITH FIXED WEIGHTS AND ADAPTIVE SELECTION OR RESYNTHESIS - A method, apparatus, and manufacture for beamforming is provided. Parameters based on sets of pre-determined beamforming weights are stored. Each of the sets of pre-determined beamforming weights has a corresponding integral index number. Each input microphone signal is transformed to the frequency domain to provide a corresponding transformed signal. Each of the transformed signals includes a plurality of subbands. Next, an index number is determined representing an optimal set of beamforming weights for the transformed signals. Then, a set of beamforming weights is applied to each subband of each of the transformed signals to provide a weighted signal. The set corresponds to the determined index number. A time domain signal is then provided by combining each of the weighted signals. | 09-18-2014 |
20140270241 | METHOD, APPARATUS, AND MANUFACTURE FOR TWO-MICROPHONE ARRAY SPEECH ENHANCEMENT FOR AN AUTOMOTIVE ENVIRONMENT - A method, apparatus, and manufacture for speech enhancement in an automotive environment is provided. Signals from first and second microphones of a two-microphone array are decomposed into subbands. At least one signal processing method is performed on the each subband of the decomposed signals to provide a first signal processing output signal and a second signal processing output signal. Subsequently, an acoustic events detection determination is made as to whether the driver, the front passenger, or neither is speaking. An acoustic events detection output signal is provided by selecting the first or second signal processing output signal and by either attenuating the selected signal or not, based on a currently selected operating mode and based on the result of the acoustic events detection determination. Each subband of the acoustics events detection output signal is then combined. | 09-18-2014 |
20150063589 | METHOD, APPARATUS, AND MANUFACTURE OF ADAPTIVE NULL BEAMFORMING FOR A TWO-MICROPHONE ARRAY - A method, apparatus, and manufacture of beamforming is provided. Adaptive null beamforming is performed for signals from first and second microphones of a two-microphone array. The signals from the microphones are decomposed into subbands. Beamforming weights are evaluated and adaptively updated over time based, at least in part, on the direction of arrival and distance of the target signal. The beamforming weights are applied to the subbands at each updated time interval. Each subband is then combined. | 03-05-2015 |
20150358732 | ADAPTIVE MICROPHONE BEAMFORMING - The present invention relates to adaptive beamforming in audio systems. More specifically, aspects of the invention relate to a method for adaptively estimating a target sound signal by establishing a simulation model simulating an audio environment comprising: a plurality of spatially separated microphones, a target sound source, and a number of audio noise sources. | 12-10-2015 |
Patent application number | Description | Published |
20130323179 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS - Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier. | 12-05-2013 |
20150086484 | Lipid-Based Drug Carriers for Rapid Penetration Through Mucus Linings - Mucus-penetrating liposomal nanoparticles and methods of making and using thereof are described herein. The nanoparticles contain one or more lipids, one or more PEG-conjugated lipids, and optionally one or more additional materials that physically and/or chemically stabilize the particles. The nanoparticle have an average diameter of about 100 nm to about 300 nm, preferably from about 100 nm to about 250 nm, more preferably from about 100 nm to about 200 nm. The particles are mobile in mucus. The liposomes can further contain one or more therapeutic, prophylactic, and/or diagnostic agent to be delivered to a mucosal surface, such as the CV tract, the colon, the nose, the lungs, and/or the eyes. The liposomes can further contain one or more CEST agents to allow real time imaging of the particles in a live animal. The particles may also further contain an imaging agent, such as a fluorescent label. | 03-26-2015 |
20150265542 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS - Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier. | 09-24-2015 |
20150265543 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS - Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier. | 09-24-2015 |