Diana
Diana Alonso Gordillo, Madrid ES
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20090069430 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS - The invention is directed to a compound of formula (I) | 03-12-2009 |
20110092591 | PHENYL-PRENYL DERIVATIVES, OF MARINE AND SYNTHETIC ORIGIN, FOR THE TREATMENT OF COGNITIVE, NEURODEGENERATIVE OR NEURONAL DISEASES OR DISORDERS - The present invention is related to a family of phenyl-prenyl derivatives of formula (I), and to their use in the treatment of cognitive, neurodegenerative or neuronal diseases or disorders, such as Alzheimer's disease or Parkinson's Disease. The present invention also relates to pharmaceutical compositions comprising the same. Further, the present invention is directed to the compounds of formula (I) for medical use, particularly for the use for the treatment and/or prevention of a cognitive, neurodegenerative or neuronal disease or disorder, and to the use of the compounds in the manufacture of a medicament for the treatment and/or prevention of a cognitive, neurodegenerative or neuronal disease or disorder. | 04-21-2011 |
20110144148 | ACETYLCHOLINESTERASE DUAL INHIBITORS - The invention provides compounds of formula: | 06-16-2011 |
Diana Anca, New York, NY US
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20120143003 | MOUTHPIECE AND METHODS OF USE OF SAME - Various embodiments of mouthpieces for use during endoscopic procedures are disclosed herein. According to various embodiments, a mouthpiece may include a shield, a primary instrument channel, a bite block, an oxygen administration channel and a tongue depressor. The shield, bite block, oxygen administration channel and tongue depressor may be integrally formed. | 06-07-2012 |
20130197657 | CENTRAL AIRWAY STENT - The present invention relates to central airway stents, and methods and devices for deploying such stents. The central airway stents are useful for maintaining or prolonging the patency of a central airway. | 08-01-2013 |
20140209095 | MOUTHPIECE AND METHODS OF USE OF SAME - Various embodiments of mouthpieces for use during endoscopic procedures are disclosed herein. According to various embodiments, a mouthpiece may include a shield, a primary instrument channel, a bite block, an oxygen administration channel and a tongue depressor. The shield, bite block, oxygen administration channel and tongue depressor may be integrally formed. | 07-31-2014 |
Diana Averill-Bates, Montreal CA
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20080254439 | Plant Extract and Use Thereof as a Cryoprotective Agent - A cryopreservation medium comprising a protein-containing plant extract is disclosed. Methods, compositions, uses and kits for cryopreservation of biological material, such as a molecule, organelle, cell, embryo, tissue or organ, are also disclosed. | 10-16-2008 |
Diana Baradarian, Old Westbury, NY US
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20110275277 | Adjustable Bra - The adjustable bra of the present invention includes an adjustment element that permits adjustment of the length of the front, adjustment of the length of the side, and/or adjustment of the length of the back, and/or adjustment of the cup size. The bra comprises a pair of bra cups and a band, the band comprising a front underbust band attached to and underlying the bra cups, a back band, and a pair of length adjustment elements for independently adjusting the length of the band. | 11-10-2011 |
Diana Becker, Neu Wulmsdorf DE
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20110124738 | CHROMATE-FREE CORROSION PROTECTION FOR FUEL TANKS - The present invention relates to a chromate-free composition, to the use thereof for corrosion protection, and to a corrosion protection coating for the inside surfaces of fuel tanks, wherein the composition comprises binding agents, hardening agents, corrosion inhibitors and quaternary ammonium compounds in a quantity of at least 0.1% by weight. | 05-26-2011 |
20150079298 | PROCESS FOR COATING METALLIC SURFACES WITH COATING COMPOSITIONS CONTAINING PARTICLES OF A LAYERED DOUBLE HYDROXIDE - Coating a metallic surface with at least one of a pretreatment composition prior to organic coating, with a passivation composition without intent for subsequent organic coating, with a pretreatment primer composition, with a primer composition, with a paint composition and with an electrocoating composition, wherein the coating composition includes particles on a base of at least one layered double hydroxide (LDH) phase characterized by the general formula [M | 03-19-2015 |
Diana Bevan, Ridgeville CA
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20100017962 | Dual comfort bed sheet set - One embodiment of a fitted bottom sheet, top sheet, and pillow case bedding set wherein each of the left and right hand sides of the bottom sheet and top sheet and each side of the pillow case is composed of a different material thus allowing individuals requiring differing temperature or material properties for their bed sheets to share the same bed. Other embodiments are described. | 01-28-2010 |
Diana Biskupski, Bayreuth DE
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20100301871 | GAS SENSOR - An electrochemical gas sensor is provided. The gas sensor includes a first electrode and a second electrode wherein the two electrodes are connected via an ion-conducting material. The first electrode is covered, at least in part, by a first catalytically active material. This top layer permits the catalytic reaction of gases. Thermally and chemically stable catalysts such as SCR or NO | 12-02-2010 |
20130285682 | GAS SENSOR - A combined gas sensor includes a first electrode and a second electrode, wherein the first and second electrodes are connected via an ion-conducting material. The first electrode is covered, in part, by a first catalytically active material. Further, a resistive gas sensor formed by a third electrode is arranged such that the third electrode is in direct contact with the first catalytic material and is not in direct contact with the first electrode. | 10-31-2013 |
Diana Blithe, Silver Springs, MD US
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20090192130 | Method for Treating Uterine Fibroids - The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. | 07-30-2009 |
Diana Bocskai, Sunnyvale, CA US
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20090276714 | GRAPHICAL STORAGE SYSTEM VISUALIZATION, TIMELINE BASED EVENT VISUALIZATION, AND STORAGE SYSTEM CONFIGURATION VISUALIZATION - A method and system for visually displaying and navigating a computer storage system are disclosed. The storage system can be graphically browsed to select a particular entity in the storage system. A graphical timeline of events relating to the selected entity is displayed. Selecting an event from the timeline displays a graphical representation of the storage system at a time relating to the selected event or additional graphical detail about the selected event. Based on the selected event, configuration information for the entity in the storage system that experienced the event can be displayed and compared against the configuration of the entity at a different time or against a predefined template. | 11-05-2009 |
20140109014 | GRAPHICAL STORAGE SYSTEM VISUALIZATION, TIMELINE BASED EVENT VISUALIZATION, AND STORAGE SYSTEM CONFIGURATION VISUALIZATION - A method and system for visually displaying and navigating a computer storage system are disclosed. The storage system can be graphically browsed to select a particular entity in the storage system. A graphical timeline of events relating to the selected entity is displayed. Selecting an event from the timeline displays a graphical representation of the storage system at a time relating to the selected event or additional graphical detail about the selected event. Based on the selected event, configuration information for the entity in the storage system that experienced the event can be displayed and compared against the configuration of the entity at a different time or against a predefined template. | 04-17-2014 |
Diana Chen, Fremont, CA US
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20110235669 | ENHANCED VBASIS LASER DIODE PACKAGE - A substrate having an upper surface and a lower surface is provided. The substrate includes a plurality of v-grooves formed in the upper surface. Each v-groove includes a first side and a second side perpendicular to the first side. A laser diode bar assembly is disposed within each of the v-grooves and attached to the first side. The laser diode bar assembly includes a first adhesion layer disposed on the first side of the v-groove, a metal plate attached to the first adhesion layer, a second adhesion layer disposed over the metal plate, and a laser diode bar attached to the second adhesion layer. The laser diode bar has a coefficient of thermal expansion (CTE) substantially similar to that of the metal plate. | 09-29-2011 |
Diana Cherbavaz, San Francisco, CA US
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20120028264 | METHOD FOR USING GENE EXPRESSION TO DETERMINE PROGNOSIS OF PROSTATE CANCER - Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein. | 02-02-2012 |
20130196321 | Gene Expression Profile Algorithm and Test for Determining Prognosis of Prostate Cancer - The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient. | 08-01-2013 |
20140303002 | Gene Expression Profile Algorithm and Test for Determining Prognosis of Prostate Cancer - The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient. | 10-09-2014 |
Diana De Falco, Roma IT
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20110014223 | MULTIMERIC PROTEINS ABLE TO INDUCE AN ANTIBODY RESPONSE AGAINST THE BETA-AMYLOID AND USE THEREOF - The present invention relates to the fields of molecular biology, immunology and medicine. Peptide sequences that belong to the beta amyloid peptide are exposed on the surface of a multimeric structure derived from the E2 component of alpha keto acid dehydrogenase. The molecules are useful for the production of vaccines for the treatment and/or prevention of Alzheimer's disease. | 01-20-2011 |
Diana Deley, St Catherines CA
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20100069178 | SPORTS GOAL NETS - The present invention provides an apparatus to stop and/or return shots for use with a sports goal net having a goal frame with a pair of posts and a cross bar connected to one end of each of pair of posts. The pair of posts and top cross bar defining a goal opening. The apparatus includes a first side deflector, shaped to cover part of the goal opening, and connected to one of the pair of posts by a first connector means adapted to permit the first side deflector to rotate about the post from a first closed position in front of the goal opening to one or more open positions to the outside of said post. A second side deflector, shaped to cover the remaining part of the goal opening, is connected to the other of said pair of posts by second connector means adapted to permit the second side deflector to rotate about the post from a first closed position in front of the goal opening to one or more open positions to the outside of said post. When in the closed position, the sports goal net can be used as a practice device for shooting and increasing accuracy of movable objects, such as pucks or balls or the like, whereby the objects are deflected back to the user for ease of self practice. | 03-18-2010 |
Diana Derval, Amsterdam NL
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20110178437 | Hormonal quotient profile calculator - A hand held device ( | 07-21-2011 |
Diana Doetsch Nee Boos, Mainz DE
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20110062108 | PE MOULDING COMPOSITION FOR PRODUCING INJECTION-MOLDED SCREW CAP CLOSURES AND HIGH-STRENGHT SCREW CAP FOR CARBONATED BEVERAGES PRODUCES THEREWITH - The invention relates to a polyethylene moulding composition having a multimodal molecular mass distribution and comprising a first ethylene homopolymer fraction (I), a second ethylene copolymer fraction (II) and a third ethylene copolymer fraction (III). The moulding composition has a density at a temperature of 23° C. in the range from 0.945 to 0.953 g/cm | 03-17-2011 |
Diana Dötsch, Mainz DE
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20120108752 | Polyethylene Moulding Composition - A novel polyethylene composition is described. The composition is suitable for manufacturing especially stretched bands or tapes, also coined raffia in the art. | 05-03-2012 |
20120214926 | Novel Trimodal Polyethylene for use in Blow Moulding - A novel polyethylene formed by Ziegler catalyst is devised, for use in blow moulding. | 08-23-2012 |
Diana Duenchel, Andernach DE
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20110248488 | Pivotable Roll Bar - The present invention relates to a roll bar for a cab-less construction machine, in particular a vibration roller, which is implemented so it is adjustable in height between an operating position and a transport position. The roll bar includes a pivotable tube bow, which comprises two vertical pivot tubes; two stand tubes, which are fixedly connected to the frame of the construction machine; two connection elements, via which the pivot tubes are connected to the stand tubes, the connection elements each comprising a stop surface, against which the pivot tube can be moved to, in particular pressed, in the operating position; a lock for clamping the pivot tube against the connection element in the operating position; a welding surface, to which the stand tube is materially bonded; and a pivot joint having a pivot axis, around which the pivot tubes are pivotable. The connection elements each comprise two sheet-metal parts, which are symmetrical to one another, the stop surfaces and the welding surfaces being implemented as edge profiles of the sheet-metal parts, and the welding surfaces being oriented essentially horizontally. | 10-13-2011 |
20110299916 | Device For Fastening A Rollbar Or Similar Attachment Part On A Vehicle - A device for fastening a rollbar or similar attachment part on a vehicle, in particular a vibration roller, includes an inner installation sleeve, which is or can be operationally linked to a bar receptacle on the vehicle, an outer installation sleeve, which at least partially encloses the inner installation sleeve and is or can be operationally linked to the rollbar, and at least one elastomeric element, which positions the inner installation sleeve relative to the outer installation sleeve in such a way that the two sleeves are spaced apart from one another while partially forming a vibration clearance. In addition, the present invention relates to a rollbar or similar attachment parts for attachment on a vehicle, in particular on a vibration roller, having at least one device according to the above-mentioned type, which is implemented, in particular integrated on the rollbar. | 12-08-2011 |
Diana Dumouchel, Calgary CA
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20100077576 | Rotatable Interlocking Pin System - A rotatable interlocking pin system to secure a plurality of fabrics together. The system includes a decorative first member, a second decorative member, and a coupling pin for rotatably joining the first and second members together to secure the plurality of fabrics. The first end is rotatably and captively received by the first member's shaft hole, while the second end pierces through the fabrics and is frictionally received by the second member's shaft hole. The members and the coupling pin are free to rotate, thus preventing the fabric from being torn, distorted, or severely damaged by the pin system. The first and second members may be constructed of a variety of decorative or simulative appearances creating coordinating or contrasting members. | 04-01-2010 |
Diana Egoo, Karmiel IL
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20110098549 | System and a method for monitoring - A disposable monitor, including an adhesive sensing unit that includes a flexible conductive wire of length that does not exceed few centimeters; wherein when the adhesive sensing unit is attached to the skin of a person the flexible conductive wire changes an electrical parameter in response to movements of the skin; wherein the adhesive sensing unit wirelessly transmits electromagnetic signals that are indicative of values of the electrical parameter of the flexible conductive wire. | 04-28-2011 |
Diana Felnerova, Bern CH
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20090087453 | Virosome particles comprising antigens from influenza virus and hepatitis b virus - The present invention provides a virosome comprising a virosomal membrane comprising at least one lipid and envelope proteins of an enveloped virus and of the virosome and attached to said envelope proteins. Furthermore, the invention provides a vaccine comprising the virosome of the invention and, a method for the production of a virosome of the invention. Moreover, the invention provides a use of a virosome of the invention for the preparation of a vaccine, e.g. for the prevention or alleviation of a disease related to an HBV infection, and a method for the vaccination of a subject. | 04-02-2009 |
Diana Frechilla Manso, Navarra ES
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20080200470 | Diaza- or Thiazadione Derivatives With Neuroprotective Activity - The present invention relates to certain derivatives of cycloalkanediones invariably substituted with a chroman-2-yl, 2-quinolyl or —O-phenyl residue which are serotonin (5-hydroxytryptamine, 5-HT) 5-HT | 08-21-2008 |
Diana Garcia Del Barco Herrera, Ciudad Habana CU
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20100136062 | USE OF EPIDERMAL GROWTH FACTOR FOR THE MORPHOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY - The invention relates to human medicine and to the use of epidermal growth factor (EGF) for preparing a pharmaceutical composition which is administered by infiltration into the periphery of nerve ganglia and/or trunks for the morphofunctional restoration of peripheral nerves in painful sensory-motor neuropathy as well as manifestations of ischemic neuritis. The invention also includes a composition containing EGF which can be formulated together with anaesthetics or analgesics or encapsulated in microspheres and to the use thereof for the morphofunctional restoration of peripheral nerves in painful sensitive-motor-type diabetic neuropathy and the manifestations of ischemic neuritis. | 06-03-2010 |
20140105990 | USE OF EPIDERMAL GROWTH FACTOR FOR THE MORPHOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY - The present invention is relevant to human medicine, and, in particular, to the use of Epidermal Growth Factor (EGF) in a pharmaceutical composition, said composition is administered through infiltration at the periphery of nerve trunks and/or ganglia, for the morphofunctional restoration of peripheral nerves in painful, sensitive-motor neuropathy, as well as ischemic neuritis. It is also relevant to an EGF containing composition, where this molecule can be formulated together with anesthetic or analgesic drugs, or encapsulated in microspheres, and their use for the morphofunctional restoration of peripheral nerves in painful, sensitive-motor neuropathy, as well as in ischemic neuritis. | 04-17-2014 |
Diana Golodnitsky, Rishon Lezion IL
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20090142656 | 3-D MICROBATTERIES BASED ON INTERLACED MICRO-CONTAINER STRUCTURES - An electrical energy storage device ( | 06-04-2009 |
20130157149 | RECHARGEABLE ALKALI METAL-AIR BATTERY - An energy storage cell ( | 06-20-2013 |
20130244102 | ELECTROPHORETIC DEPOSITION OF THIN FILM BATTERIES - Methods for forming three-layer thin-film battery (TFB) structures by sequential electrophoretic deposition (EPD) on a single conductive substrate. The TFBs may be two-dimensional or three-dimensional. The sequential EPD includes EPD of a first battery electrode followed by EPD of a porous separator on the first electrode and by EPD of a second battery electrode on the porous separator. In some embodiments of a Li or Li-ion TFB, the separator includes a Li ion conducting solid. In some embodiments of a Li or Li-ion TFB, the separator includes an inorganic porous solid rendered ionically conductive by impregnation with a liquid or polymer. In some embodiments, the TFBs are coated and sealed with an EPDd PEEK layer. | 09-19-2013 |
Diana Golodnitsky, Rishon Letzion IL
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20110045351 | High-Power Nanoscale Cathodes for Thin-Film Microbatteries - A method, including placing a substrate of a battery in a bath consisting of a metal M chosen from a metal group consisting of Fe, Ni, Co, Cu, W, V, and Mn, an oxidant selected from an oxidant group consisting of oxygen and sulfur, and a polymer. The method also includes applying an electrical current so as to form on the substrate a metal M compound cathode having a nanoscale grain structure. | 02-24-2011 |
Diana Graus Porta, Basel CH
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20090062320 | Method of Treating Disorders Mediated by the Fibroblast Growth Factor Receptor - The disclosure includes a method of treating a warm-blooded animal having a disorder mediated by the fibroblast growth factor receptor (FGFR), in particular 8p11 myelo-proliferative syndrome (EMS), pituitary tumors, retinoblastoma, synovial sarcoma, chronic obstructive pulmonary disease (COPD), seborrheic keratosis, obesity, diabetes and related disorders, autosomal dominant hypophosphatemic Rickets (ADHR), X-chromosome linked hypophosphatemic rickets (XLH), tumor-induced osteomalacia (TIO) and fibrous dysplasia of the bone (FD), as well as to a method of promoting localized neochondrogenesis, as well as a method of treating hepatocellular carcinoma, lung cancer, especially pulmonary adnocarcinoma, oral squameous cell carcinoma, or esophageal squameous cell carcinoma, or any combination of two or more such diseases. | 03-05-2009 |
20100075337 | METHOD OF IDENTIFICATION OF CELLS THAT SHOW SENSITIVITY TO MODULATION OF SIGNALINGH MEDIATED BY FIBROBLAST GROWTH FACTOR RECEPTOR OR A VARIANT THEREOF - The invention is based on the finding that cells that show (especially tyrosine) phosphorylation of FGF-R substrate 2 (FRS-2), in contrast to cells that lack such phosphorylation, allow a prediction that treatment with a modulator, especially an inhibitor, of Fibroblast Growth Factor-Receptor signaling will be successful in cells e.g. from biological samples from patients that show such phosphorylation. Therefore, the phosphorylation of FRS-2 can serve as a biomarker for the possibility of successful treatment. The invention relates to various methods, uses, kits and reagents useful in applying this biomarker. | 03-25-2010 |
20100105667 | Quinoxaline- and Quinoline-Carboxamide Derivatives - The invention relates to compounds of formula (I) | 04-29-2010 |
20100120773 | METHOD OF TREATING DISORDERS MEDIATED BY THE FIBROBLAST GROWTH FACTOR RECEPTOR - The disclosure includes a method of treating a warm-blooded animal having a disorder mediated by the fibroblast growth factor receptor (FGFR), in particular 8p11 myelo-proliferative syndrome (EMS), pituitary tumors, retinoblastoma, synovial sarcoma, chronic obstructive pulmonary disease (COPD), seborrheic keratosis, obesity, diabetes and related disorders, autosomal dominant hypophosphatemic Rickets (ADHR), X-chromosome linked hypophosphatemic rickets (XLH), tumor-induced osteomalacia (TIO) and fibrous dysplasia of the bone (FD), as well as to a method of promoting localized neochondrogenesis, as well as a method of treating hepatocellular carcinoma, lung cancer, especially pulmonary adnocarcinoma, oral squameous cell carcinoma, or esophageal squameous cell carcinoma, or any combination of two or more such diseases. | 05-13-2010 |
20110045511 | METHODS OF MONITORING THE MODULATION OF THE KINASE ACTIVITY OF FIBROBLAST GROWTH FACTOR RECEPTOR AND USES OF SAID METHOD - The present invention relates generally to methods of in vitro diagnostics, in particular the use of a compound selected from the group consisting of fibroblast growth factor 23 (FGF23), inorganic phosphorus (P), the product of inorganic phosphorus and total calcium (P×tCa), osteopontin (OPN) and parathyroid hormone (PTH) as biomarker. Said biomarkers can be used to monitor the modulation of fibroblast growth factor receptor (FGFR) kinase activity, in particular its inhibition, and/or the occurrence of secondary effects of FGFR inhibition. The invention further provides methods and kits relating to these uses. | 02-24-2011 |
20120220600 | N-Oxide of 3-(2,6-dichloro-3,5-dimethoxy-phenyl) -1--1-methyl-urea - An N-oxide of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea, pharmaceutically acceptable salts thereof, compositions including the compound and its pharmaceutically acceptable salts, and methods of preparing the compound and the compositions (such as, for example, by oxidizing 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea with an oxidizing agent) are described. Further described herein are methods of using the compound and compositions of the present technology, alone and in combination with other suitable agents, to treat various diseases, including but not limited to, those that can be prevented, inhibited or ameliorated by inhibition of kinase activity selected from FGFR1, FGFR2, FGFR3 or FGFR4. | 08-30-2012 |
20120258940 | METHOD FOR TREATING HAEMATOLOGICAL CANCERS - The present invention relates to a combination which comprises (a) a FGFR inhibitor and (b) a glucocorticoid receptor modulator, or a pharmaceutical acceptable salt thereof; the use of such a combination for the preparation of a medicament for the treatment of haematological cancers; a commercial package or product comprising such a combination; and to a method of treatment of a warm-blooded animal, especially a human. | 10-11-2012 |
20120309741 | QUINOXALINE CARBOXAMIDE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS - The invention relates to compounds of formula (I) | 12-06-2012 |
20120309766 | QUINOXALINE CARBOXAMIDE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS - The invention relates to compounds of formula (I) | 12-06-2012 |
20120315648 | METHOD OF IDENTIFICATION OF CELLS THAT SHOW SENSITIVITY TO MODULATION OF SIGNALING MEDIATED BY A FIBROBLAST GROWTH FACTOR RECEPTOR OR A VARIANT THEREOF - The invention is based on the finding that cells that show (especially tyrosine) phosphorylation of FGF-R substrate 2 (FRS-2), in contrast to cells that lack such phosphorylation, allow a prediction that treatment with a modulator, especially an inhibitor, of Fibroblast Growth Factor-Receptor signaling will be successful in cells e.g. from biological samples from patients that show such phosphorylation. Therefore, the phosphorylation of FRS-2 can serve as a biomarker for the possibility of successful treatment. The invention relates to various methods, uses, kits and reagents useful in applying this biomarker. | 12-13-2012 |
20130035343 | COMBINATION OF ORGANIC COMPOUNDS - A pharmaceutical combination comprising 4-Amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one and at least one mTOR inhibitor and the pharmaceutical combination for use in treating or preventing a proliferative disease. | 02-07-2013 |
20130123272 | ORGANIC COMPOUND FOR USE IN THE TREATMENT OF LIVER CANCER - The use of 4-amino-5-fluoro-3[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one or a pharmaceutically acceptable salt or a tautomer thereof, or a hydrate or a solvate for the manufacture of pharmaceutical compositions for use in the treatment of hepatocellular carcinoma or liver cancer. | 05-16-2013 |
20130324519 | QUINOXALINE CARBOXAMIDE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS - The invention relates to compounds of formula (I) | 12-05-2013 |
20140378468 | N-Oxide of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1--1-methyl-urea - An N-oxide of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]pyrimidin-4-yl}-1-methyl-urea, pharmaceutically acceptable salts thereof, compositions including the compound and its pharmaceutically acceptable salts, and methods of preparing the compound and the compositions (such as, for example, by oxidizing 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea with an oxidizing agent) are described. Further described herein are methods of using the compound and compositions of the present technology, alone and in combination with other suitable agents, to treat various diseases, including but not limited to, those that can be prevented, inhibited or ameliorated by inhibition of kinase activity selected from FGFR1, FGFR2, FGFR3 or FGFR4. | 12-25-2014 |
20150072019 | FGFR INHIBITOR FOR USE IN THE TREATMENT OF HYPOPHOSPHATEMIC DISORDERS - The present invention relates generally to 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimid-4-yl}-1-methyl-urea or a pharmaceutically acceptable salt or solvate thereof or a pharmaceutical composition comprising 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimid-4-yl)-1-methyl-urea or a pharmaceutically acceptable salt or solvate thereof for use in the treatment of X-linked hypophosphatemic rickets (XLH), autosomal dominant hypophosphatemia rickets (ADHR), autosomal recessive hypophosphatemic rickets (ARHR), tumor-induced osteomalacia, post-renal transplant hypophosphatemia, epidermal nevus syndrome, osteoglophonic dysplasia or McCune-Albright syndrome. | 03-12-2015 |
Diana Henao, Dover, NJ US
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20090317347 | Antiperspirant/Deodorant Compositions - A composition comprising a structuring agent for the composition comprising a partially hydrogenated soybean oil with a melting point of about 26 to about 38° C. in an amount of about 5% or less by weight: and at least one active chosen from antiperspirant actives and deodorant actives in an amount of about 0.5 to about 16% by weight of the composition on an active weight basis. The composition can be used as an antiperspirant and/or deodorant when applied to an axillary area of a person. | 12-24-2009 |
Diana Hernandez-Jaramillo, London GB
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20120208273 | VESSEL FOR CULTURING CELLS - The present invention provides an apparatus for culturing cells which may comprise two or more culture compartments and a pooling compartment, wherein each of said two or more culture compartments may be separated from the other culture compartments; each of said two or more culture compartments which may comprise a port for the addition or removal of medium; and the pooling compartment communicates with said two or more culture compartments. The present invention also relates to a stand for apparatus for culturing cells. | 08-16-2012 |
Diana Kaneva, Stara Zagora BG
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20120066291 | REMOTE METHOD INVOCATION TUNNELING OVER HYPERTEXT TRANSFER PROTOCOL - Various embodiments of systems and methods for remote method invocation (RMI) tunneling over hypertext transfer protocol (HTTP) are described herein. RMI client uses HTTP client to send a protocol message in the body of an HTTP request to a special application on a server. The application dispatches the content of the message to RMI service of the server to handle remote call. RMI response may be sent in the HTTP response of the same HTTP request or some of the further requests. RMI callbacks initiated from the server back to the client are also delivered in an HTTP response of a client's HTTP request. | 03-15-2012 |
Diana Koletzki, Etterbeek BE
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20110189684 | METHOD FOR DETERMINING DRUG RESISTANCE MUTATIONS IN ANY OF THE NON-STRUCTURAL PROTEIN REGIONS NS3 TO NS5B OF HEPATITIS C VIRUS (HCV) FOR GENOTYPES 1 TO 6 - The present invention relates to a method for determining drug resistance mutations in any of the non-structural protein regions NS3 to NS5B of Hepatitis C Virus (HCV) for genotypes 1 to 6, more in particular for subtype specific genotypes 1a, 1b, 2a, 2b, 3a, 4a and 4d. | 08-04-2011 |
Diana Lacasa Mas, Barcelona ES
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20090170816 | COMBINATION COMPRISING SQUALENE, A PHOSPHOLIPID AND AN OMEGA 3 FATTY ACID FOR THE TREATMENT OF CANCER - Pharmaceutical composition which comprises squalene or its pharmaceutically acceptable derivatives; at least one phospholipid, its salts or pharmaceutically acceptable derivatives; and at least one omega-3 fatty acid, its salts or pharmaceutically acceptable derivatives. Use of the composition in the preparation of a drug designed for the prophylaxis, treatment and/or improvement of cancer symptoms in mammals. The invention also relates to a fodder for animals such as dogs and cats which comprises the composition. | 07-02-2009 |
Diana Leukel-Schafer, Darmstadt DE
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20090258806 | VOLUME GIVING CLEANSING COMPOSITION - The present invention is related to an aqueous cleansing composition especially for keratin fibres such as human hair with excellent volume enhancing effect. First object of the present invention is a cleansing composition for hair comprising at least one surfactant selected from anionic, non-ionic and amphoteric ones and furthermore comprising at least one ethoxylated monoglyceride according to the general formula | 10-15-2009 |
20090258807 | SHEAR THICKENING CLEANSING COMPOSITION - The present invention is related to an aqueous cleansing composition for keratin fibres especially human hair with shear thickening property. Specifically, present invention is on cleansing compositions for keratin fibres, especially for human hair, based on at least one anionic surfactant, especially anionic sulphate surfactant, at a concentration of 2 to 25% by weight, and further comprising at least one amino acid surfactant of the following structure | 10-15-2009 |
Diana Leukel-Schäfer, Darmstadt DE
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20110126850 | Volume Giving Cleansing Composition - The present invention is related to an aqueous cleansing composition especially for keratin fibres such as human hair with excellent volume enhancing effect. First object of the present invention is a cleansing composition for hair comprising at least one surfactant selected from anionic, non-ionic and amphoteric ones and furthermore comprising at least one ethoxylated monoglyceride according to the general formula | 06-02-2011 |
20110232668 | CLEANSING COMPOSITION - The present invention is related to an aqueous cleansing composition for keratin fibres, especially human hair, comprising at least two anionic surfactants comprising at least one amide group in their molecules. The first object of the present invention is an aqueous cleansing composition comprising at least two anionic surfactants comprising at least one amide group in their molecules and substantially frees of alkyl sulphate and alkyl ether sulphate surfactants. The two anionic surfactants comprising at least one amide group in their molecule is preferably selected from surfactants of the following structure | 09-29-2011 |
20120171146 | Shear Thickening Cleansing Composition - The present invention is related to an aqueous cleansing composition for keratin fibres especially human hair with shear thickening property. Specifically, present invention is on cleansing compositions for keratin fibres, especially for human hair, based on at least one anionic surfactant, especially anionic sulphate surfactant, at a concentration of 2 to 25% by weight, and further comprising at least one amino acid surfactant, and at least one ethoxylated monoglyceride. | 07-05-2012 |
Diana Li, Woburn, MA US
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20100171978 | DELIVERY EXPERT SYSTEM AND METHOD - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 07-08-2010 |
20110216366 | Delivery Expert System, Method and Computer Program Product - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 09-08-2011 |
20120162695 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - Embodiments disclosed herein can facilitate delivery of a document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon input conditions which may include a time-variable set of input conditions such as identifying non-business days and/or hours at the destination. The document can be a fax, an email, or a voice mail. The actions may include resubmitting the document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, identifying the destination as a technical problem, or a combination thereof. | 06-28-2012 |
20120188607 | Delivery Expert System, Method and Computer Program Product - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 07-26-2012 |
20130301075 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Rules may be stored in a database. The database may include rules based on past delivery information or new delivery instructions. When an input condition is determined, the database may be traversed to determine an action based on the set of rules. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 11-14-2013 |
20140307284 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Rules may be stored in a database. The database may include rules based on past delivery information or new delivery instructions. When an input condition is determined, the database may be traversed to determine an action based on the set of rules. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 10-16-2014 |
Diana Ludlam, New York, NY US
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20120127426 | METHOD AND SYSTEM FOR TREATING BINOCULAR ANOMALIES - A system for treating binocular anomalies. The system includes one or more imaging devices, one or more visual displays, and a computing device. The imaging devices may include right and left imaging devices that capture images of a patient's right and left eyes, respectively. The displays may include right and left displays that provide right and left visual stimulation, respectively. The computing device identifies right and left locations on the right and left retinas, respectively, based at least in part on images of right and left eyes, respectively. The brain fuses images positioned at the right and left locations on the retinas into a single image. The computing device transmits right and left positioning signals to the right and left displays, respectively, that indicate that the right and left visual stimulation, respectively, are to be displayed so they are positioned at the right and left locations, respectively, on the retinas. | 05-24-2012 |
Diana Maeker, Monheim DE
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20080234145 | Use of Lithium Salts of Fatty Alcohol Sulphates for Cleaning Boreholes, Boring Devices and Borings - The invention relates to the use of compounds of general formula (I): R—O—SO—Li | 09-25-2008 |
20120080195 | Drilling Composition, Process for its Preparation, and Applications Thereof - The present invention relates to a drilling composition comprising: I) an organic phase comprising components: i. from about 20 wt. % to about 99.999 wt. %, based on the total weight of components i. and ii., of at least one linear or branched, cyclic or non-cyclic, saturated hydrocarbon; ii. from about 0.001 wt. % to about 25 wt. %, based on the total weight of components i. and ii., of at least one ester; II) from 0 to about 50 wt. %, based on the total weight of the composition, of water or aqueous phase; III) from 0 to about 60 wt. %, based on the total weight of the composition, of at least one additive, wherein the sum of the weight components I) to III) is 100 wt. %, to a process for preparation of a drilling composition, to uses of a drilling composition, to a drilling system, to a process for making a borehole, to a process for conveying cuttings, to a process for treating a drill head, to a process for production of at least one of oil and gas. | 04-05-2012 |
20120325492 | Drilling Composition, Process for its Preparation, and Applications Thereof - A drilling composition is provided. The composition includes: I) an organic phase comprising components: i. from about 20 wt. % to about 99.999 wt. %, based on the total weight of components i. and ii., of at least one linear or branched, cyclic or non-cyclic, saturated hydrocarbon; ii. from about 0.001 wt. % to about 25 wt. %, based on the total weight of components i. and ii., of at least one ester; II) from 0 to about 50 wt. %, based on the total weight of the composition, of water or aqueous phase; III) from 0 to about 60 wt. %, based on the total weight of the composition, of at least one additive, wherein the sum of the weight components I) to III) is 100 wt. %. | 12-27-2012 |
20140151061 | DRILLING COMPOSITION, PROCESS FOR ITS PREPARATION, AND APPLICATIONS THEREOF - A drilling composition is provided. The composition includes: I) an organic phase comprising components: i. from about 20 wt. % to about 99.999 wt. %, based on the total weight of components i. and ii., of at least one linear or branched, cyclic or non-cyclic, saturated hydrocarbon; ii. from about 0.001 wt. % to about 25 wt. %, based on the total weight of components i. and ii., of at least one ester; II) from 0 to about 50 wt. %, based on the total weight of the composition, of water or aqueous phase; III) from 0 to about 60 wt. %, based on the total weight of the composition, of at least one additive, wherein the sum of the weight components I) to III) is 100 wt. %. | 06-05-2014 |
Diana Mäker, Monheim DE
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20120080232 | Emulsion-Based Cleaning Composition For Oilfield Applications - The present invention relates to an emulsion, consisting of an oil phase and an aqueous phase and comprising as emulsion components (α1) 15 to 40% by weight of at least one water-immiscible organic solvent as solvent of the oil phase, (α2) 15 to 40% by weight of water as solvent of the aqueous phase, (α3) 10 to 40% by weight of at least one surfactant, (α4) 10 to 40% by weight of an alkoxylated fatty alcohol and (α5) 0 to 25% by weight of at least one other additive, wherein the quantities by weight of the components (α1) to (α5) are each relative to the total weight of the emulsion, and together add up to 100% by weight. The invention further relates to a method for producing an emulsion, to the emulsion which can be obtained from said method, to the use of an emulsion, to a method for cleaning the surfaces of well holes, drilling devices or drillings, to a method for producing a well bore, and to a method for producing an oil or a gas. | 04-05-2012 |
Diana Mandelker, Baltimore, MD US
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20100316995 | CONSENSUS CODING SEQUENCES OF HUMAN BREAST AND COLORECTAL CANCERS - Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of ˜90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention and monitoring. | 12-16-2010 |
Diana Manzanedo, Cambridge, MA US
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20090088681 | DEVICE AND METHOD FOR THE TREATMENT OF INTRA-ABDOMINAL DISEASE - An apparatus, such as a medical device, includes an elongate member having a proximal end portion and a distal end portion. The elongate member defines a lumen extending from the proximal end portion to the distal end portion. The distal end portion of the elongate member is configured to be inserted into a body of a patient. The apparatus includes a heating element configured to heat the lumen defined by the elongate member such that a material within the lumen is heated and can be delivered to bodily tissue. | 04-02-2009 |
Diana Marrero, Bristol, CT US
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20100158829 | Method and Composition for Color Modulation - The invention is directed to a method and composition suitable for skin color modulation. Particularly, the action of D-dopachrome tautomerase on melanogenesis and/or the transfer of melanin from melanosomes in keratinocytes is reduced, thereby resulting in a change in skin color. | 06-24-2010 |
Diana Martin Lorenzo, Tres Cantos ES
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20110190164 | CHIMERIC FUSION PROTEINS AND VIRUS LIKE PARTICLES FROM BIRNAVIRUS VP2 - The field of the invention refers to chimeric Virus Like Particles (VLP) derived from Birnavirus chimeric VP2 protein. In particular, the invention refers to chimeric VP2 fusion proteins which incorporate insertions and/or substitutions with one or more amino acids or particular peptide of interest while maintaining the capacity to assemble in the form of VLP. The invention identifies particular insertion and/or substitutions sites within VP2 P loop regions and outside said P loop regions. The invention also incorporates methods for the identification of preferred insertion and substitution sites within VP2 for the incorporation of particular amino acids and peptides of interest. The resulting chimeric VLP are of interest in the design of therapeutic and prophylactic vaccines as well as in the design of drug delivery systems, carriers for DNA and RNA in gene therapy, as targeted agents, in the development of antitoxins, and as diagnostic reagents. | 08-04-2011 |
Diana Mechtcheriakova, Wien AT
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20080318255 | Fluorescent Labeled Sphingosines - The present invention relates to a method (assay) for determining the activity of an enzyme selected from the group consisting of a sphingosine kinase and a phosphatase involved in the sphingolipid pathway by use of a labeled sphingosine. | 12-25-2008 |
20090209495 | USE OF EDG RECEPTOR BINDING AGENTS IN CANCER - Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine- | 08-20-2009 |
20100029007 | Biomarker in Inflammatory Diseases - The use of CD1B, or CD1D, respectively as a target for a disorder selected from Systemic Lupus Erythematosus (SLE), Lupus Anticoagulant (LA) Rheumatoid Arthritis (RA) and Idiopathic Thrombocytopenic Purpura; and the use of CD1D as a target in a disorder which is Multiple Sclerosis (MS), e.g. as a biomarker; a method for preparing a diagnostic kit and a method for identifying agents that modulates a disorder which is mediated by elevated levels of CD1B, or CD1D, respectively, in case of CD1B, or CD1D, respectively selected from Systemic Lupus Erythematosus (SLE), Lupus Anticqagulant (LA) Rheumatoid Arthritis (RA) and Idiopathic Thrombocytopenic Purpura; and in case of CD1D a disorder which is Multiple Sclerosis (MS). | 02-04-2010 |
Diana Menaged, Ambler, PA US
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20110026854 | Ecologically Safe Storage Bag and Transporting System and Method of Making Same - The present invention is directed to a storage system including a biodegradable plastic material that can be used in applications where biodegradability and biocompatibility are among primary desirable features, while having qualities which are desired for the various uses of the storage system. The present invention includes process to make the storage system and for transporting article wherein they can be stored at their destination. | 02-03-2011 |
Diana Mikiewicz-Sygula, Warszawa PL
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20110136736 | NEW INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 06-09-2011 |
20140121353 | INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 05-01-2014 |
20140315247 | Expression Cassette, Use of the Expression Cassette, Expression Vector, Prokaryotic Host Cell Comprising Expression Vector, Bacterial Strain and a Method for Producing a Polypeptide - The subject matters of invention relate to expression cassette, use of the expression cassette, expression vector, prokaryotic host cell harbouring expression vector, bacterial strain, and method for producing a polypeptide. In more detail, the invention relate to stable expression of recombinant polypeptides, in systems with no need of using antibiotics. Particularly, stable expression of recombinant proteins obtained with the use of very efficient T7 polymerase/promoter system. | 10-23-2014 |
Diana Mikiewicz-Sygula, Czestochowa PL
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20100297773 | EXPRESSION CASSETTE, USE OF THE EXPRESSION CASSETTE, VECTOR, HOST CELL, A METHOD FOR PRODUCING A POLYPEPTIDE - The subject matters of invention relate to expression cassette, use of the expression cassette, vector, host cell, a method for producing a polypeptide ensuring its stable expression by the prokaryotic host as well as an use of the expression cassette. The invention enables stable expression of the target polypeptide, in systems where DNA-dependent RNA polymerase recognises promoter regulating synthesis of target protein as well as selection marker, which is required for survival of the host. | 11-25-2010 |
Diana Milirud, Bellevue, WA US
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20100262814 | HANDLING EXCEPTIONS RELATED TO CORRUPT APPLICATION STATE - An exception handling system is described herein that provides one or more distinguished classes of software exceptions that are handled differently than other exceptions. The system treats a distinguished exception as a “hard to catch” exception that is not passed to the catch block of program code unless a developer performs extra steps to acknowledge the distinguished nature of the exception and confirm that the program code is prepared to properly handle the exception. Exceptions that fall into this class are typically those that represent conditions from which normal exception handling practices cannot successfully recover, namely exceptions that corrupt application state. Accordingly, the system prevents the developer from catching these classes of exceptions by default unless the developer explicitly requests to have these exceptions delivered to the program code. Thus, the exception handling system encourages correct programming practices by preventing developer error by default. | 10-14-2010 |
Diana Milirud, Newcastle, WA US
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20120304026 | SEPARATION OF ERROR INFORMATION FROM ERROR PROPAGATION INFORMATION - A system and method for handling exceptions in a multi-threaded computing environment. Information, such as that relating to an error state or pertaining to the propagation history of an exception, is stored in a separate object from the exception object itself. The separate propagation information object is accessible to the plurality of threads that are used to execute a user task. The separate object allows rich diagnostic information pertaining to the exception and its propagation through multiple threads to be presented to the developer of the software. | 11-29-2012 |
Diana Mueller, Guetersloh DE
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20080257970 | Method for Controlling a Heating Device and System for Carrying Out Said Method - A method for controlling a warming device includes: providing a system including the warming device and a household appliance, the system configured to at least one of process and prepare at least one of a beverage and a food; and automatically turning on a heating element of the warming device by a selection of a future activation time at which the household appliance is switched from a standby state to an ON state, the selection being made using the household appliance. | 10-23-2008 |
Diana Nersesian, Gurnee, IL US
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20080234308 | Amino-Aza-Adamantane Derivatives and Methods of Use - The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to α7 nicotinic acetylcholine receptors also are described. | 09-25-2008 |
Diana Nguyen-Thien-Nhoh, Irvine, CA US
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20100036484 | LOW PROFILE TRANSCATHETER HEART VALVE - An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame. | 02-11-2010 |
Diana Nguyen-Thien-Nhon, Irvine, CA US
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20100057193 | FLEXIBLE HEART VALVE AND ASSOCIATED CONNECTING BAND - A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. The stent may be cloth-covered and may be a single element or may be made in three separate elements for a three cusp valve, each element having a cusp portion and two commissure portions; adjacent commissure portions for each pair of adjacent stent element combining to form the stent commissures. If the stent has separate elements their commissure portions may be pivotably or flexible coupled, or may be designed to completely separate into independent leaflets at bioresorbable couples. The cloth covering may have an outwardly projecting flap that mates with valve leaflets (e.g., pericardial leaflets) along the cusps and commissures. A connecting band may be provided that follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered silicon member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. The connecting band includes commissure portions defining generally axial gaps that help permit flexing of the valve. | 03-04-2010 |
20110319991 | Low Profile Transcatheter Heart Valve - An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame. | 12-29-2011 |
Diana Oehms, Ludwigshafen DE
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20100292120 | Detergent Composition - A detergent composition comprising an enzyme and a bleaching compound and comprising two or more distinct regions, wherein the enzyme is located in a first distinct region and the bleaching compound is located in a second distinct region and further wherein a builder comprising an amino acid based compound and/or succinate based compound is located in the first distinct region. The compositions exhibit improved stability of the enzyme. | 11-18-2010 |
20110062620 | Process for Making a Pellet - The invention comprises a shaping process for making pellets of a thermoplastic extrudable resin composition. The resin composition comprises a thermoplastic polymer, plasticiser and optionally further additives. The plasticiser comprises a component which is solid at room temperature. The process is run at a temperature above the melting point of the plasticiser and below the melting/plastification temperature of the thermoplastic polymer. | 03-17-2011 |
Diana Pehlman-Wilkin, Plano, TX US
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20080257637 | Disposable Stethoscope Head Cover and Automated Dispensing Apparatus Therefor - A method and apparatus for the prevention of carryover infection due to surface contamination on a stethoscope features a disposable stethoscope head cover implemented with hypoallergenic materials and a dispensing apparatus that automatically places a disposable stethoscope head cover in an attachment station, allowing a simple single handed attachment of the disposable stethoscope head cover to the stethoscope. | 10-23-2008 |
Diana Pesha, Chicago, IL US
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20090159518 | METHOD OF PRODUCING A REDUCED-CALORIE FOOD PRODUCT - Calories in a juice can be reduced by selectively removing more sucrose than primary sugars, for example, glucose and fructose. An acceptable flavor profile can be achieved since the primary sugars have a higher perceived sweetness than sucrose. The food product processing system for reducing calories can include multiple stages for filtering the juice to produce a clarified low-calorie juice having an acceptable flavor profile. | 06-25-2009 |
Diana Ravich, Natania IL
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20100140850 | Compositions for 3D printing - Described is a composition for solid freeform fabrication (SFF) at a given dispensing temperature. The composition comprises: a curable component having a monofunctional (meth)acrylic functional group; a photo-initiator, and a sulfur-containing additive. The viscosity of the composition, as measured at the given dispensing temperature, changes by no more than 3 cps during 30 days of aging at 40° C. | 06-10-2010 |
20130241114 | SYSTEM AND METHOD FOR ADDITIVE MANUFACTURING OF AN OBJECT - A method of additive manufacturing of a three-dimensional object is disclosed. The method comprises sequentially forming a plurality of layers in a configured pattern corresponding to the shape of the object. Each layer is formed by dispensing at least one modeling material to form an uncured layer, and curing the uncured layer by radiation. In various exemplary embodiments of the invention the method comprises, for at least one layer, forming a stack of sacrificial radiation-protective layers to cover an exposed portion of the layer, such that an upper layer of the stack remains exposed during formation of any subsequent layer of the plurality of layers. | 09-19-2013 |
Diana Riano-Gordo, Cerezo De Rio Tiron ES
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20100139153 | Method of Improving Oil Compositions - A method of improving the low temperature properties of an oil comprising fatty acid alkyl esters derived from plant or animal materials, wherein at least 5% by weight of the fatty acid alkyl esters are derived from C | 06-10-2010 |
Diana Rodekohr, Solingen DE
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20080307702 | Method and Device for Treating Trees - There are described a devices for the treatment of woody plants, comprising a cylindrical injection element ( | 12-18-2008 |
20090325807 | Method of Improving Plant Growth - The present invention relates to a method of improving the growth of plants selected from the group of amenity trees and forest trees comprising applying to said plants or the locus thereof at least one compound selected from the class of agonists and antagonists of the nicotinic acetylcholine receptors. | 12-31-2009 |
Diana Roloff US
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20100236548 | Soft bite block and method for making soft bite block - A soft bite block device for preventing contact between upper and lower teeth of an anesthetized patient. The device includes an elongate roll of cotton gauze encircled by permeable tape so as to maintain the rolled gauze as a monolithic structure. The device is disposable, absorbent and aseptic or sterile. The device is contained within an aseptic or sterile package for the protection of the patient. | 09-23-2010 |
Diana Schenkwein, Kuopio FI
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20090011509 | INTEGRASE FUSION PROTEINS AND THEIR USE WITH INTEGRATING GENE THERAPY - In a method of targeting intergration of a transgene comprising retrovirus-like DNA into a eukaryotic genome, the genome is cleared by an endonuclease and the transgene is introduced at the site of cleavage, wherein the endonuclease is specific to a site in an abundant rDNA locus and is fused to an integrase that mediates the introduction of the transgene. The fusion protein may be new. | 01-08-2009 |
20100221791 | Method for Incorporating Proteins Into Lentivirus Vectors - The present invention is a method for incorporating an integrase-fusion protein into a third-generation lentivirus vector, comprising: (i) transfecting a vector packaging plasmid into a producer cell, wherein the vector packaging plasmid contains a lentivirus transfer construct and a gene encoding the integrase-fusion protein, said gene being fused to the pol-polyprotein gene; (ii) transcription and translation of the genes; and (iii) release of the integrase-fusion protein from the pol-polyprotein. | 09-02-2010 |
Diana Schmidt, Roth DE
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20100272273 | DEVICE FOR ACOUSTICALLY ANALYZING A HEARING DEVICE AND ANALYSIS METHOD - A device for acoustic analysis has a first hearing device with a first sound input and a first sound output and a second hearing device with a second sound input and a second sound output. The first hearing device is in acoustic communication with the second hearing device. The first hearing device can analyze the acoustic communication and output a corresponding result. Consequently, two hearing aids, for example, can test each other, and permit a user to check hearing devices and, in particular, hearing aids in a simple fashion without the hearing aid wearer having to visit an audiologist for the test. | 10-28-2010 |
Diana Schroen, Sandia Park, NM US
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20120305490 | OIL ABSORBANT POLYOLEFIN FOAM - Described herein are polyolefin open cell foam materials that absorb organic liquids or waxes, such as hydrocarbon oil, selectively against water. The polyolefin open cell foam materials are environmentally friendly, have a relatively low bulk density, and can be used in the clean up of oil spills. | 12-06-2012 |
Diana Schuhbauer, Basel CH
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20090252724 | Antibodies Against Amyloid Beta 4 With Glycosylated in the Variable Region - The present invention relates to a purified antibody molecule preparation being characterized in that at least one antigen binding site comprises a glycosylated asparagine (Asn) in the variable region of the heavy chain (V | 10-08-2009 |
Diana Shadeed, Easton, PA US
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20120022099 | NOVEL POLYMORPHIC FORMS OF AN AZABICYCLO-TRIFLUOROMETHYL BENZAMIDE DERIVATIVE - The present disclosure is directed to solid forms of the compound of formula (I): | 01-26-2012 |
Diana Shapirov, Yokneam Elit IL
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20110199764 | DEVICE AND METHOD FOR CONTROLLING AN ANGULAR COVERAGE OF A LIGHT BEAM - A system and method for controlling an angular coverage of a light beam. The method includes: defining a non-uniform angular coverage of a first light beam; altering a first spatial relationship between a first movable transmissive deflector and a first light source in response to the definition; directing a first light beam from the first light source through the first movable transmissive deflector such as to provide a first deflected light beam; and focusing the first deflected beam, by a first optical focusing element, to provide a first focused light bean that is focused onto a first area that is characterized by a location that is substantially indifferent to changes in the first spatial relationship. | 08-18-2011 |
Diana Shapirov, Yokneam IL
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20100110418 | METHOD AND SYSTEM FOR DEFECT DETECTION USING TRANSMISSIVE BRIGHT FIELD ILLUMINATION AND TRANSMISSIVE DARK FIELD ILLUMINATION - A method for defect detection using transmissive bright field and transmissive dark field illumination, the method includes: determining a relationship between at least one transmissive bright field illuminator ( | 05-06-2010 |
20110102771 | SYSTEMS AND METHODS FOR NEAR INFRA-RED OPTICAL INSPECTION - An inspection system and a method for defect detection, the method includes: generating a first beam that comprises a near infrared spectral component and a visible light component; directing at least the near infrared spectral component of the first beam towards an inspected object; directing, towards a sensor, a near infrared spectral component of a second beam generated from the illuminating of the inspected object; wherein the sensor is sensitive to visual light radiation and to near infrared radiation; generating, by the sensor, detection signals that are responsive to the near infrared component of the second beam; and detecting defects in the inspected object by processing the detection signals. | 05-05-2011 |
20110115903 | INSPECTION SYSTEM AND METHOD FOR HIGH SPEED IMAGING - A method and an inspection system, the inspection system includes a camera comprising multiple pixels having a pixel width; a mechanical stage, for introducing a movement between an inspected object and optics of the inspection system; wherein the inspected object is expected to move a distance that substantially equals the pixel width during a pixel movement period; an illumination module and optics for illuminating inspected portions of the inspected object and for directing light from the inspected portions to the camera; and wherein the camera is arranged to acquire multiple acquired images of the inspected portions during each pixel movement period, wherein at least two acquired images partially overlap. | 05-19-2011 |
20140022541 | SYSTEMS AND METHODS FOR NEAR INFRA-RED OPTICAL INSPECTION - An inspection system and a method for defect detection, the method includes: generating a first beam that includes a near infrared spectral component and a visible light component; directing at least the near infrared spectral component towards a backside of an inspected object, the backside includes first elements made of a substantially transparent to near infrared radiation first material and second elements that are made of a second material arranged to reflect near infrared radiation; directing, towards a sensor, a near infrared spectral component of a second beam generated from the illuminating of the inspected object; wherein the sensor is sensitive to visible light radiation and to near infrared radiation; generating, by the sensor, detection signals that are responsive to the near infrared component of the second beam; and detecting at least one attribute of at least the second elements by processing the detection signals. | 01-23-2014 |
Diana Shpektor, Shoreline, WA US
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20100254978 | ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 - The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules. | 10-07-2010 |
20130330344 | ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 - The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules. | 12-12-2013 |
Diana Shvydka, Toledo, OH US
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20100304512 | System for Diagnosis and Treatment of Photovoltaic and Other Semiconductor Devices - A diagnostic and self-healing treatment system for a semiconductor device, the system provides: i) a shunt busting/blocking treatment, ii) self-healing treatment, and iii) an in-situ non-contact diagnostic determination. | 12-02-2010 |
20110048534 | Nanodipole Photovoltaic Devices, Methods of Making and Methods of Use Thereof - A photovoltaic device includes a built-in electric field generated by electric dipoles of nanoparticles embedded in a photoconducting host. | 03-03-2011 |
Diana Sibayan, Denver, CO US
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20100031420 | Shoulder Compression Garment - The present invention provides athletic apparel principally for bicycling. The invention provides a shoulder compression garment for bicycling configured to maintain a user's shoulders in a position closer to a user's medial torso plane relative to a relaxed position of the user's shoulders. | 02-11-2010 |
Diana Sidrak, Van Nuys, CA US
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20110042971 | Electronic Door Chain - An electronic door chain which has a receiving hole drilled into the slotted keeper for a electric solenoid shaft to be inserted into which will prevent sliding of the chain out of the groove unless the solenoid is released by entering a pre-programmed access number on the access keypad in which case the solenoid shaft is retracted in response to the access keypad output. Concurrently, the solenoid shaft will retract to the open position and a short beep will be generated to announce to anyone within hearing distance that the electronic door chain is disengaged. | 02-24-2011 |
Diana Smetters, Belmont, CA US
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20090187982 | Systems and methods for authenticating communications in a network medium - A system and method for sharing files securely includes server software on a first device configured to communicate with server software operating on one or more other preauthorized devices, such as a second device. The servers communicate with each other securely using cryptographic information exchanged during a preauthorization phase using a range-limited communication channel. The server on the first device obtains file information from the other preauthorized device(s) and combines the information with local file information from the first device. This combined file information is sent to client software operating on the machine, which presents the combined file information to users. | 07-23-2009 |
Diana Tharalson, Agoura, CA US
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20090090302 | PET CO-SLEEPER - A pet co-sleeper is designed to be connected to a human's bed for use by small to medium sized animals. Pets such as dogs and cats can use this sleeper to sleep beside their owners instead on of the bed. The pet co-sleeper has a frame which is substantially rectangular in shape. The frame has three horizontal bars forming a three-sided top frame and a fourth horizontal bar on the fourth side is lower than the other three horizontal bars. Fabric materials attached to the frame form a floor, four side walls and a horizontal divider located just below the fourth horizontal bar. A first mattress is placed over the horizontal divider to form a sleeping surface. A second mattress is placed on the fabric floor, such that the four side walls, the second mattress and the horizontal divider form a pet house. | 04-09-2009 |
20120266380 | BED SIDE SLEEPER FOR INFANTS - A sleeper for infants is described. The sleeper has four short legs, a frame supported by the legs and a bassinette hanging from the frame. The sleeper can rest on its legs for use in a stand-alone state, or be mounted on a playard for use as a bedside sleeper. When mounted on a playard, the sleeping surface of the sleeper has approximately the same height as an adult's bed. | 10-25-2012 |
Diana Velluto, Lausanne CH
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20100055189 | Nanoparticles for immunotherapy - Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics. Surface chemistries and chemical formulations for the nanoparticles are described. | 03-04-2010 |
20110223217 | BLOCK COPOLYMERS AND USES THEREOF - An encoding/decoding apparatus and method using a low-density parity-check code (LDPC code) is disclosed. Basic column group information, serving as a set of information regarding positions of rows with weight 1, is extracted from a reference column in each column group of a predetermined parity-check matrix. Column group information transforms the positions of rows with weight 1 into positions whose lengths are within a required parity length. A parity-check matrix is generated according to the generated column group information. Data is encoded or decoded based on the generated parity-check matrix. | 09-15-2011 |
Diana Von Olnhausen, Snohomish, WA US
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20120090078 | Suspenders For Women - A method for use by a woman wearing a bra and wearing pants having belt loops, to provide a certain support for the pants. The method makes use of a generally flexible article, having a top portion generally in shape of a V and a bottom and having a hook at the top of each branch of the V and a downwardly extending hook at the bottom. The hook on the top of each branch of the V IS hooked to a shoulder strap of the bra and the hook at the bottom of the article is hooked to one of the belt loops | 04-19-2012 |
Diana Vucina, Pacific Grove, CA US
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20110282705 | Project Management Systems and Methods - Embodiments of the present invention provide improved project management systems and methods. In one embodiment the present invention includes a project management system comprising a plurality of radial task regions displayed around a focal point and a plurality of time regions displayed around the focal point, wherein each time region represents a period of time. The present invention may be implemented in software or as a project management template provided on a sheet of material such as paper. | 11-17-2011 |
Diana Wagner, Hersbruck DE
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20110083582 | PIGMENT MIXTURE OF PVD ALUMINIUM EFFECT PIGMENTS AND THIN ALUMINIUM EFFECT PIGMENTS FROM MILLING, PROCESS FOR PREPARATION THEREOF AND USE THEREOF - A mixture of aluminum effect pigments, the mixture comprising: | 04-14-2011 |
Diana Walter, Valen DE
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20100322879 | WETTING AND DISPERSING AGENT - Low-VOC mixture of at least partially salified copolymers of at least one ethylenically unsaturated, phenyl-group-containing monomer and at least one α,β-unsaturated monocarboxylic acid and/or at least one α,β-unsaturated dicarboxylic acid, of at least one water-soluble polyether, esterification products of at least one water-soluble polyether and an aliphatic dicarboxylic acid, and of a star polymer obtainable by esterifying a carboxylic acid containing at least 3 carboxyl groups with at least one water-soluble polyether, and use thereof as a wetting and dispersing agent, preferably for producing low-VOC pigment pastes or low-VOC paint systems. | 12-23-2010 |
Diana Wattel-Beenhouwer, Vlissingen NL
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20100139707 | WASHABLE FILMIC LAMINATES - A process for removing a washable PSA laminate from a substrate is provided. The process comprises contacting the washable PSA laminate with water and optionally, a base, at a temperature sufficient to remove the washable PSA laminate from the substrate; wherein the washable PSA laminate comprises at least one facestock layer, at least one adhesive base layer, and at least one tackifier layer; wherein the facestock layer comprises at least one facestock material; wherein the adhesive base layer comprises at least one adhesive base polymer; wherein the tackifier layer comprises at least one tackifier and optionally at least one adhesive base polymer; wherein the tackifier layer is applied to the adhesive base layer side of the washable PSA laminate. Specifically, a process is provided for removing a washable PSA laminate from a bottle comprising contacting the washable PSA laminate with water and optionally, a base, at a temperature sufficient to remove the washable PSA laminate from the bottle. | 06-10-2010 |
Diana Zipeto US
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20090124015 | Modular chemistry analyzer - A chemistry analyzer is disclosed that can include a unitary base with vertical and horizontal supports for constraining subassemblies. The subassemblies include at least a reagent/sample carousel subassembly, a transfer arm subassembly, and a reaction carousel subassembly. A centralized hydraulic system can also be provided behind a user access panel. The analyzer can use machine-readable test specifications coupled with its reagent vessels to define tests that include operations that employ the reagents. The analyzer can also display to the operator a pictorial representation that includes graphical elements that convey levels of usage for the storage vessels, and access icons that are each associated with a color and each lead to a set of screens for different types of operations for the analyzer. | 05-14-2009 |