Patent application number | Description | Published |
20080268645 | METHOD FOR FRONT END OF LINE FABRICATION - In one embodiment, a method for removing native oxides from a substrate surface is provided which includes supporting a substrate containing silicon oxide within a processing chamber, generating a plasma of reactive species from a gas mixture within the processing chamber, cooling the substrate to a first temperature of less than about 65° C. within the processing chamber, and directing the reactive species to the cooled substrate to react with the silicon oxide thereon while forming a film on the substrate. The film usually contains ammonium hexafluorosilicate. The method further provides positioning the substrate in close proximity to a gas distribution plate, and heating the substrate to a second temperature of about 100° C. or greater within the processing chamber to sublimate or remove the film. The gas mixture may contain ammonia, nitrogen trifluoride, and a carrier gas. | 10-30-2008 |
20110223755 | METHOD FOR REMOVING OXIDES - A method for removing native oxides from a substrate surface is provided. In one embodiment, the method comprises positioning a substrate having an oxide layer into a processing chamber, generating a plasma of a reactive species from a gas mixture within the processing chamber, exposing the substrate to the reactive species while forming a volatile film on the substrate and maintaining the substrate at a temperature below 65° C., heating the substrate to a temperature of at least about 75° C. to vaporize the volatile film and remove the oxide layer, and depositing a first layer on the substrate after heating the substrate. | 09-15-2011 |
20120244704 | METHOD FOR REMOVING OXIDES - A method for removing native oxides from a substrate surface is provided. In one embodiment, the method comprises positioning a substrate having an oxide layer into a processing chamber, exposing the substrate to a gas mixture while forming a volatile film on the substrate and maintaining the substrate at a temperature below 65° C., heating the substrate to a temperature of at least about 75° C. to sublimate the volatile film and remove the oxide layer, and depositing a first layer on the substrate after heating the substrate. | 09-27-2012 |
Patent application number | Description | Published |
20100035815 | SKIN WOUND HEALING COMPOSITIONS AND METHODS OF USE THEREOF - A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound. | 02-11-2010 |
20100172886 | Method for Promoting Wound Healing - The present invention discloses a method for treating wounds and for accelerating the healing of wounds by administering an effective amount of a pharmaceutical composition containing type VII collagen protein, mini-C7 protein, variants thereof or any combinations thereof. The pharmaceutical composition may be administered through a variety of routes including intravenous injection, topical application, or oral ingestion. The method may further include administering a genetically modified fibroblast capable of expressing type VII collagen protein, mini-C7 protein, variants thereof or small growth factors to achieve synergistic healing effect. | 07-08-2010 |
20110082082 | SKIN WOUND HEALING COMPOSITIONS AND METHODS OF USE THEREOF - A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 pg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed. | 04-07-2011 |
20110301090 | SKIN WOUND HEALING COMPOSITIONS AND METHODS OF USE THEREOF - A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound. | 12-08-2011 |
20120121595 | FRAGMENT OF SECRETED HEAT SHOCK PROTEIN-90ALPHA (Hsp90ALPHA) AS VACCINES OR EPITOPE FOR MONOCLONAL ANTIBODY DRUGS OR TARGET FOR SMALL MOLECULE DRUGS AGAINST A RANGE OF SOLID HUMAN TUMORS - The invention provides methods for treating HIF-1α-overexpressing human tumors, inhibiting HIF-1α-overexpressing tumor invasion and preventing tumor metastasis, and/or promoting tumor prophylaxis, using various types of inhibitors against the Hsp90α from the tumors. | 05-17-2012 |
20120308537 | Use Of Collagen Type VII For Maintaining And Re-Inducing Osteogenic Abilities Of Mesenchymal Stem Cells - This invention provides methods of inducing and maintaining osteogenic potential in mesenchymal stem cells and compositions for doing the same. The compositions this invention comprise collagen 7 (C7), the NC1 domain of C7, or the 27 kD fragment of C7. Also provided are methods for treating bone diseases and correcting bone defects by applying compositions of this invention or by first priming ex vivo mesenchymal stem cells with compositions of this invention and then applying the primed mesenchymal stem cells to the patient. The invention further provides a mesenchymal stem cell osteogenesis induction kit. | 12-06-2012 |
20120329719 | Methods of use of skin wound healing compositions - A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed. | 12-27-2012 |
20130150305 | Method for Promoting Wound Healing - The present invention discloses a method for treating wounds and for accelerating the healing of wounds by administering an effective amount of a pharmaceutical composition containing type VII collagen protein, mini-C7 protein, variants thereof or any combinations thereof. The pharmaceutical composition may be administered through a variety of routes including intravenous injection, topical application, or oral ingestion. The method may further include administering a genetically modified fibroblast capable of expressing type VII collagen protein, mini-C7 protein, variants thereof or small growth factors to achieve synergistic healing effect. | 06-13-2013 |
20130237485 | Methods and Agents for Enhancing Wound Healing - This invention discloses a method of inducing expression of full-length collagen 7 in cells that contain nonsense mutations in the COL7A1 gene by treating the cell with an aminoglycoside such as G418, gentamicin, and paromomycin. Also provided is a method of treating DEB due to nonsense mutation in the COL7A1 gene by administering a composition containing an effective amount of an aminoglycoside. Also provided is a novel composition useful to treating conditions due to nonsense mutation in the COL7A1 gene, containing an aminoglycoside, a C7, a min-C7 or both; and a pharmaceutically acceptable carrier. | 09-12-2013 |
20130243822 | Composition and Method for Healing of Skin Wounds - This invention provides compositions and methods for topically treating skin wounds. The composition comprises C7, C7M, a variant thereof, or a combination thereof in a pharmaceutically acceptable carrier. The method comprises the steps of topically applying compositions of this invention to the skin wound. | 09-19-2013 |
20140031295 | Recombinant C7 and Methods of Use - The present disclosure provides methods of treating epidermolysis bullosa, and/or preventing, preventing the progression of, or delaying the onset of one or more symptom associated with scarring, e.g., of blisters, in subjects with epidermolysis bullosa through chronic systemic administration of collagen 7. | 01-30-2014 |
20140199309 | FRAGMENT OF SECRETED HEAT SHOCK PROTEIN-90ALPHA (HSP90ALPHA) AS VACCINES OR EPITOPE FOR MONOCLONAL ANTIBODY DRUGS OR TARGET FOR SMALL MOLECULE DRUGS AGAINST A RANGE OF SOLID HUMAN TUMORS - The invention provides methods for treating HIF-1α-overexpressing human tumors, inhibiting HIF-1α-overexpressing tumor invasion and preventing tumor metastasis, and/or promoting tumor prophylaxis, using various types of inhibitors against the Hsp90α from the tumors. | 07-17-2014 |
20150313967 | Methods and Agents for Wound Healing - This invention provides compositions and methods for topically treating skin wounds. The composition comprises C7, C7M, a variant thereof, or a combination thereof in a pharmaceutically acceptable carrier. The method comprises the steps of topically applying compositions of this invention to the skin wound. | 11-05-2015 |
20160053003 | COMPOSITIONS AND METHODS FOR TREATING HIF-1a OVER-EXPRESSING CANCERS - Described herein are compositions that include monoclonal antibodies that specifically bind Hsp90α and methods of using the same to treat HIF-1a-overexpressing cancer. In some embodiments, the cancers are breast cancer or lung cancer. The monoclonal antibodies bind the epitope TKPIWTRNP in Hsp90α or VKHFSVEGQ in Hsp90α. | 02-25-2016 |
Patent application number | Description | Published |
20090286752 | ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF - The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine analog substantially in the stomach. Also provided are methods of treating diseases and disorders using the oral formulations provided herein. | 11-19-2009 |
20120196823 | PHARMACEUTICAL COMPOSITIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF - The present disclosure provides pharmaceutical compositions comprising cytidine analogs for parenteral administration. Also provided are methods of preparing the compositions and methods of treating diseases and disorders using the compositions provided herein. | 08-02-2012 |
20130267530 | SOLID FORMS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR - The present invention provides a solid form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibit desirable characteristics for the same. | 10-10-2013 |
20130267531 | SALTS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR - The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same. | 10-10-2013 |
20150051157 | ROMIDEPSIN FORMULATIONS AND USES THEREOF - Provided herein are formulations of romidepsin. Also provided are methods for producing these formulations and uses thereof. In one embodiment, the formulation is a combination of romidepsin and mannitol. | 02-19-2015 |
20150056280 | ISOTOPOLOGUES OF 5-AZACYTIDINE - The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine analog substantially in the stomach. Also provided are methods of treating diseases and disorders using the oral formulations provided herein. | 02-26-2015 |
20150290228 | ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF - The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine analog substantially in the stomach. Also provided are methods of diffuse large B-cell lymphoma, follicular lymphoma, or mantel cell lymphoma, which comprises administering to a human having diffuse large B-cell lymphoma, follicular lymphoma, or mantel cell lymphoma a therapeutically effective amount of 5-azacytidine, or a pharmaceutically acceptable salt, solvate or hydrate thereof, and optionally administering therapeutically effective amounts of one or more additional active agents. | 10-15-2015 |
20150344441 | SALTS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR - The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same. | 12-03-2015 |
20150374732 | ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF - The present disclosure provides pharmaceutical compositions comprising cytidine analogs for oral administration, wherein the compositions release the cytidine analog substantially in the stomach. Also provided are methods of treating diseases and disorders using the oral formulations provided herein. | 12-31-2015 |
20160022677 | SOLID FORMS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR - The present invention provides a solid form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibit desirable characteristics for the same. | 01-28-2016 |
20160074399 | Salts of an Epidermal Growth Factor Receptor Kinase Inhibitor - The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same. Examples include hydrobromide and bis-besylate salts of N-(3-(2-(4-(4-acerylpiperazin-1-yl)-2-methoxyphenylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)phenyl)acrylamide). The salts and their polymorphs are evaluated for their properties such as stability, solubility, and pharmacokinetics. | 03-17-2016 |
Patent application number | Description | Published |
20120040439 | Use of Prokaryote Viruses to Remediate Bio-Fouling - This invention provides a process for control in oil and gas wells and related facilities of prokaryote caused souring, fouling and corrosion by reduction of problematic prokaryotes with naturally occurring lysing organisms, particularly sulfate-reducing prokaryotes by proliferating suitable virulent lysing organisms under conditions in which problematic prokaryotes thrive, including in a gas production wellbore. The process provides in situ proliferation of virulent lysing organism in a wellbore by providing both virulent lysing organisms and their host prokaryotes to selectively grow an effective control amount and concentrations of lysing organisms in a well formation. | 02-16-2012 |
20130072706 | Recovery of Oleaginous Tricyglycerols from Wastewater Title of Invention Treatment Plant Foams - Tricyglycerols that may be converted to biofuel are recovered from oleaginous organisms in the natural and induced foam of wastewater treatment process plants. Growing oleaginous organisms in the form of comparatively dry foam simplifies harvest and is more efficient and efficacious than skimming the biomass off the top of the liquids that rely on less efficient centrifugation or filtration methods typically required to concentrate cells grown in liquids. | 03-21-2013 |
20130149753 | Application of Bacteriophages for the Control of Unwanted Bacteria in Biofuel Production Mediated by Non-Bacterial Reactive Agents - A method of reducing process interruptions in biofuel production systems by reducing the amount of unwanted bacteria in the biofuel production system in which the reduction is effected by the use of an effective amount of one or more types of bacteriophages virulent for at least some strains of the unwanted bacteria. | 06-13-2013 |
20130149759 | Application of Bacteriophages for the Control of Unwanted Bacteria in Biofuel Production Mediated by Bacterial Reactive Agents - A method of reducing process interruptions in biofuel production systems mediated by bacterial reactive agents by reducing the amount of unwanted bacteria without reduction of wanted or useful bacteria. The method comprises applying a phage panel(s) containing phage virulent for unwanted bacteria that does not contain phage phages virulent wanted bacteria. The method includes, optionally, the selective production of solutions of phage for unwanted bacteria from which phages for wanted bacteria are screened out. | 06-13-2013 |
20140061123 | Prevention and Remediation of Petroleum Reservoir Souring and Corrosion by Treatment with Virulent Bacteriophage - There is provided a safe, natural, environmentally sound means of controlling bacterial contamination, corrosion, and souring of oil and gas wells and reservoirs that result from bacteria-contaminated water in a well. In one aspect it is a process for remediation of souring of petroleum reservoirs and coalbeds by adding to the water used in flooding and “fracing” operations an effective amount of virulent (non-lysogenic) bacteriophages (phages) specific for problematic target bacteria. The invention also provides a means for combating loss of effectiveness of bacterial control by staging bacteriophage production and application to control dominant and sub-dominant target bacteria in a community of target bacteria. | 03-06-2014 |
20140148379 | Control of Unwanted Bacteria in Fermentation Systems with Bacteriocin - A method of controlling unwanted bacteria in fermentation processes comprising contacting reactants of the process with an effective amount of bacteriocin. Bacteriocin, both indigenous and produced from independent sources, and optionally bacteriocin plus bacteriophages virulent for unwanted bacteria are used to reduce and control unwanted bacteria. | 05-29-2014 |
20140273159 | Staged Bacteriophage Remediation of Target Bacteria - A process for remediation of target bacteria, particularly sulfur reducing bacteria (SRB), in waters (“target water”) having a multiplicity and diverse host target bacteria by employing serial or staged bacteria culturing and lysing of dominant bacteria. Remediation of sulfur reducing bacteria (SRB) is effected by application of a series of bacteriophage isolated from the staged culturing and bacteriophage lysing of successive aliquots of waters containing a multiplicity of SRB. | 09-18-2014 |
20150320829 | Broad Spectrum Bacteriocin for Control of Unwanted Bacteria - A composition containing a newly identified bacteriocin produced by a | 11-12-2015 |
Patent application number | Description | Published |
20110146925 | ALDEHYDE-FUNCTIONALIZED POLYMERS WITH ENHANCED STABILITY - The current invention includes a composition having stability additives of selected inorganic salts and/or organic incorporated into an aldehyde-functionalized polymer product. The stability additive can be post added to the finished polymer product, added to the reaction vessel prior to inducing functionalization of the non-functionalized polymer, or added at any stage during the functionalization reaction. Methods for forming the composition and using the composition to produce a cellulosic fiber-based medium are also disclosed. | 06-23-2011 |
20130192782 | METHOD OF USING ALDEHYDE-FUNCTIONALIZED POLYMERS TO INCREASE PAPERMACHINE PERFORMANCE AND ENHANCE SIZING - Disclosed herein are compositions and methods to increase paper machine performance and enhance sizing. The compositions include a sizing agent, an emulsifier, and an aqueous component. The emulsifier may be an aldehyde-functionalized polymer. | 08-01-2013 |
20140060763 | ALDEHYDE-FUNCTIONALIZED POLYMERS WITH ENHANCED STABILITY - The current invention includes a composition having stability additives of selected inorganic salts and/or organic incorporated into an aldehyde-functionalized polymer product. The stability additive can be post added to the finished polymer product, added to the reaction vessel prior to inducing functionalization of the non-functionalized polymer, or added at any stage during the functionalization reaction. Methods for forming the composition and using the composition to produce a cellulosic fiber-based medium are also disclosed. | 03-06-2014 |
20140130994 | EMULSIFICATION OF ALKENYL SUCCINIC ANHYDRIDE WITH AN AMINE-CONTAINING HOMOPOLYMER OR COPOLYMER - The present disclosure provides for a method of preparing and using an emulsion for treating a papermaking process. The emulsion is an oil-in-water emulsion of alkenyl succinic anhydride emulsified with a polymer comprising at least one primary or secondary amine containing monomer. The method comprises adding an oil-in-water emulsion to the papermaking process; wherein the oil-in-water emulsion comprises alkenyl succinic anhydride emulsified with a polymer comprising at least one primary or secondary amine containing monomer; and wherein the oil-in-water emulsion is added in an amount sufficient to improve sizing of the paper produced by the papermaking process. The primary or secondary amine may be a secondary amine comprising diallylamine, and the polymer may be a diallylamine-acrylamide copolymer. | 05-15-2014 |
20140336314 | METHOD OF USING ALDEHYDE-FUNCTIONALIZED POLYMERS TO INCREASE PAPERMACHINE PERFORMANCE AND ENHANCE SIZING - Disclosed herein are compositions and methods to increase paper machine performance and enhance sizing. The compositions include a sizing agent, an emulsifier, and an aqueous component. The emulsifier may be an aldehyde-functionalized polymer. The sizing agent may be selected from rosin size, an alkyl ketene dimer, an alkenyl succinic anhydride, and any combination of these sizing agents. | 11-13-2014 |
20150020988 | Emulsification of Alkenyl Succinic Anhydride with an Amine-Containing Homopolymer of Copolymer - The present disclosure provides for a method of preparing and using an emulsion for treating a papermaking process. The emulsion is an oil-in-water emulsion of alkenyl succinic anhydride emulsified with a polymer comprising at least one primary or secondary amine containing monomer. The method comprises adding an oil-in-water emulsion to the papermaking process; wherein the oil-in-water emulsion comprises alkenyl succinic anhydride emulsified with a polymer comprising at least one primary or secondary amine containing monomer; and wherein the oil-in-water emulsion is added in an amount sufficient to improve sizing of the paper produced by the papermaking process. The primary or secondary amine may be a secondary amine comprising diallylamine, and the polymer may be a diallylamine-acrylamide copolymer. | 01-22-2015 |
20150041088 | USE OF NANOCRYSTALINE CELLULOSE AND POLYMER GRAFTED NANOCRYSTALINE CELLULOSE FOR INCREASING RETENTION IN PAPERMAKING PROCESS - The invention provides methods and compositions for improving the characteristics of paper substrates. The method involves adding to a paper substrate an NCC-polymer. NCC-polymers have unique chemical properties which result in improvements in wet strength, dry strength and drainage retention properties of the paper substrates. | 02-12-2015 |
20150041089 | USE OF NANOCRYSTALINE CELLULOSE AND POLYMER GRAFTED NANOCRYSTALINE CELLULOSE FOR INCREASING RETENTION IN PAPERMAKING PROCESS - The invention provides methods and compositions for improving the characteristics of paper substrates. The method involves adding to a paper substrate an NCC-polymer. NCC polymers have unique chemical properties which result in improvements in wet strength, dry strength and drainage retention properties of the paper substrates. | 02-12-2015 |
20150041091 | USE OF NANOCRYSTALINE CELLULOSE AND POLYMER GRAFTED NANOCRYSTALINE CELLULOSE FOR INCREASING RETENTION, WET STRENGTH, AND DRY STRENGTH IN PAPERMAKING PROCESS - The invention provides methods and compositions for improving the characteristics of paper substrates. The method involves adding to a paper substrate an NCC-polymer. NCC-polymers have unique chemical properties which result in improvements in wet strength, dry strength and drainage retention properties of the paper substrates. | 02-12-2015 |
20150197893 | WET END CHEMICALS FOR DRY END STRENGTH IN PAPER - The invention provides methods and compositions for increasing the dry strength of paper. The invention utilizes a tailored strength agent whose size and shape is tailored to fit into the junction points between flocs of a paper sheet. The strength agents is in contact with the slurry for just enough time to collect at the junction points but not so much that it can migrate away from there. | 07-16-2015 |
20160097160 | METHOD OF INCREASING PAPER BULK STRENGTH BY USING A DIALLYLAMINE ACRYAMIDE COPOLYMER IN A SIZE PRESS FORMULATION CONTAINING STARCH - The invention provides methods and compositions for increasing the strength of a paper sheet. The method involves adding to the paper sheet an amine containing polymer. The amine containing polymer interacts with materials such as GPAM or starch to make the paper stronger in terms including tensile strength, surface strength and bulk strength. | 04-07-2016 |
20160097161 | METHOD OF INCREASING PAPER STRENGTH - The invention provides methods and compositions for increasing the strength of a paper sheet. The method involves adding to the paper sheet an amine containing polymer. The amine containing polymer interacts with materials such as GPAM or starch to make the paper stronger in terms including tensile strength, surface strength and bulk strength. | 04-07-2016 |
Patent application number | Description | Published |
20130165873 | METHODS, DEVICES AND SYSTEMS FOR TREATING AND/OR DIAGNOSIS OF DISORDERS OF THE EAR, NOSE AND THROAT - A method for irrigating a paranasal sinus may involve advancing a distal portion of a sinus irrigation catheter through an ostium of a paranasal sinus into the sinus and passing fluid through multiple ports disposed at different locations along a length of the catheter distal portion into the sinus. A flexible irrigation catheter device for irrigating a paranasal sinus may include: an elongate catheter body having a proximal end, a distal end, a lumen therebetween, and a tapered distal portion extending proximally from the distal end of the catheter body; a proximal hub coupled with the proximal end of the catheter body for connecting to a source of irrigation fluid; multiple side ports disposed along the catheter body closer to the distal end than the proximal end and in fluid communication with the lumen; and a distal end port at the distal end of the catheter body. | 06-27-2013 |
20140330074 | SHAPEABLE GUIDE CATHETERS AND RELATED METHODS - Shapeable guide catheters and methods for manufacturing and using such shapeable guide catheters. In one embodiment, the shapeable guide catheter comprises a tubular member having a shapeable region, a malleable shaping member attached to the shapeable region such that, when the shape of the shapeable region is changed from a first shape to a second shape, the shaping member will plastically deform to thereafter substantially hold the shapeable region in the second shape, a tubular outer jacket disposed about the outer surface of the tubular member and a tubular inner jacket disposed within the lumen of the tubular member. The shapeable region of the guide catheter may be manually formed into a desired shape before insertion of the guide catheter into the body. In some embodiments, the guide catheter is sized to be inserted through a nostril of a human patient and used to guide the transnasal insertion of another device (e.g., a guidewire, catheter, etc.) to a desired location within the nose, throat, ear or cranium of the subject. | 11-06-2014 |
Patent application number | Description | Published |
20110074511 | LAYOUT AND PAD FLOOR PLAN OF POWER TRANSISTOR FOR GOOD PERFORMANCE OF SPU AND STOG - A power transistor for use in an audio application is laid out to minimize hot spots. Hot spots are created by non-uniform power dissipation or overly concentrated current densities. The source and drain pads are disposed relative to each other to facilitate uniform power dissipation. Interleaving metal fingers and upper metal layers are connected directly to lower metal layers in the absence of vias to improve current density distribution. This layout improves some fail detection tests by 17%. | 03-31-2011 |
20130169362 | INPUT CLAMPING STRUCTURE FOR SOUND QUALITY IMPROVEMENT IN CAR-RADIO CLASS-AB POWER AMPLIFIER DESIGN - A clamping circuit for a class AB amplifier includes a reference voltage circuit, four NPN Darlington transistors having inputs coupled to the reference voltage circuit, and outputs for providing four clamped voltages, and a split NPN Darlington transistor having an input coupled to the reference voltage circuit, and four separate outputs for providing four AC ground voltages. | 07-04-2013 |
20130188793 | EMBEDDED SPEAKER PROTECTION FOR AUTOMOTIVE AUDIO POWER AMPLIFIER - A method of operating a speaker system including a speaker coupled to an amplifier, and a dedicated digital speaker protection circuit includes turning on the amplifier in a mute mode, after a first delay period, issuing a play command to the amplifier to place the amplifier in a play mode, but without an input signal during a second delay period, and performing a speaker offset detection during the second delay period, wherein, if there is an offset, then the amplifier is forced back into the mute mode, and if there is no offset, then the amplifier is allowed to continue to operate in the play mode. The method also includes issuing a speaker protection control signal or command if an offset is detected. | 07-25-2013 |
20130267087 | LAYOUT AND PAD FLOOR PLAN OF POWER TRANSISTOR FOR GOOD PERFORMANCE OF SPU AND STOG - A power transistor for use in an audio application is laid out to minimize hot spots. Hot spots are created by non-uniform power dissipation or overly concentrated current densities. The source and drain pads are disposed relative to each other to facilitate uniform power dissipation. Interleaving metal fingers and upper metal layers are connected directly to lower metal layers in the absence of vias to improve current density distribution. This layout improves some fail detection tests by 17%. | 10-10-2013 |
20150137888 | INPUT CLAMPING STRUCTURE FOR SOUND QUALITY IMPROVEMENT IN CAR-RADIO CLASS-AB POWER AMPLIFIER DESIGN - A clamping circuit for a class AB amplifier includes a reference voltage circuit, four NPN Darlington transistors having inputs coupled to the reference voltage circuit, and outputs for providing four clamped voltages and a split NPN Darlington transistor having an input coupled to the reference voltage circuit, and four separate outputs for providing four AC ground voltages. | 05-21-2015 |
20150304773 | EMBEDDED SPEAKER PROTECTION FOR AUTOMOTIVE AUDIO POWER AMPLIFIER - A method of operating a speaker system including a speaker coupled to an amplifier, and a dedicated digital speaker protection circuit includes turning on the amplifier in a mute mode, after a first delay period, issuing a play command to the amplifier to place the amplifier in a play mode, but without an input signal during a second delay period, and performing a speaker offset detection during the second delay period, wherein, if there is an offset, then the amplifier is forced back into the mute mode, and if there is no offset, then the amplifier is allowed to continue to operate in the play mode. The method also includes issuing a speaker protection control signal or command if an offset is detected. | 10-22-2015 |
20150381125 | POWER AMPLIFIER - A power amplifier includes a clamping circuit configured to provide a clamped voltage from a power supply; an amplifier pair having first inputs coupled to the clamping circuit, second inputs and an output for providing an amplified signal; and a biasing circuit coupled between the clamping circuit and the second inputs. The biasing circuit is configured to adjust input bias voltages of the amplifier pair such that the bias voltage of the output of the amplifier pair varies proportionally to a change of the power supply. | 12-31-2015 |
Patent application number | Description | Published |
20090117601 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases. AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 05-07-2009 |
20110262957 | COMPOSITIONS FOR THE DETECTION OF INTRACELLULAR BACTERIAL TARGETS AND OTHER INTRACELLULAR MICORORGANISM TARGETS - Presented herein are solid supports on or in which a composition comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent) is present in added form. Presented herein are also methods for detecting the presence of an intracellular microorganism target (e.g., an intracellular bacterial target) utilizing such solid supports. Further, presented herein are tablets as well as dry powders comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent), and methods of using such tablets and dry powders to detect the presence of an intracellular microorganism target (e.g., an intracellular bacterial target). | 10-27-2011 |
20120077215 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 03-29-2012 |
20140080164 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 03-20-2014 |
20160138076 | Methods And Compositions For The Detection Of Beta-Lactamases - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 05-19-2016 |
Patent application number | Description | Published |
20130223760 | Microscopic image fusion method based on region growing - A microscopic image fusion method based on region growing judges the fuzzy degree of the microscopic image and determines the fuzzy seed block by evaluating the definition of every image block in the microscopic image. Then, the fuzzy region and clear region are exactly segmented by region growing and are marked. Finally, a clear and high-quality microscopic image, fused by a plurality of microscopic images, is obtained. Due to the combination of the definition evaluation of the microscopic image, and segmentation of the fuzzy region and clear region by region growing, the fusion results of the microscopic image of the present invention show great advantages at the subjective human perception and the objective evaluation. Furthermore, the present invention has simple calculation and stable result, is easy to be implemented and adapted for fusing the digital optical microscopic images which are shot by shallow depth of field. | 08-29-2013 |
20140029000 | Method for detecting parfocality of zoom-stereo microscope - A method for detecting a parfocality of a zoom-stereo microscope includes: acquiring four highest definitions corresponding to a plurality of images with a cooperation of four definition judging functions, acquiring a relatively clearest position according to the four highest definitions, comparing a definition in the relatively clearest position with a definition in a parfocal position to judge whether the relatively clearest position is the parfocal position, then adjusting a magnification of the zoom-stereo microscope to acquire the parfocal positions at a finite number of the discrete magnifications, and finally fitting a parfocal curve at the continuous magnifications. The method according to the present invention implements a parfocality detection of the stereo microscope automatically and effectively and increases a productivity, and has a high detecting precision. In addition, the method according to the present invention has a good robustness, so that users needn't intervene and adjust frequently. | 01-30-2014 |
20140064604 | Method for objectively evaluating quality of stereo image - A method for objectively evaluating quality of a stereo image is provided. The method obtains a cyclopean image of a stereo image formed in the human visual system by simulating a process that the human visual system deals with the stereo image. The cyclopean image includes three areas: an occlusion area, a binocular fusion area and a binocular suppression area. Representing characteristics of the image according to the singular value of the image has a strong stability. According characteristics of different areas of the human visual system while dealing with the cyclopean image, the distortion degree of the cyclopean image corresponding to the testing stereo image is presented by the singular value distance between cyclopean images respectively corresponding to the testing stereo image and the reference stereo image, in such a manner that an overall visual quality of the testing stereo image is finally evaluated. | 03-06-2014 |
20140169661 | Method of color correction of pair of colorful stereo microscope images - A method for color correction of a pair of colorful stereo microscope images is provided, which transmits the color information of the foreground areas and the background area of the reference image to the aberrated image separately for avoiding transmission error of the color information of the varied areas of the pair of the images, thus sufficiently improves the accuracy of the color correction, reduces the difference between the color of the reference image and the color of the aberrated image, and well prepares for the stereo matching of the pair of colorful stereo microscope images as well as for the three-dimensional reconstruction and three-dimensional measurement; on the other hand, during the correction, the correcting procedure is provided automatically without manual work. | 06-19-2014 |
20150093016 | Digital watermarking based method for objectively evaluating quality of stereo image - A digital watermarking based method for objectively evaluating quality of stereo image includes: at transmitting terminal, extracting characteristics of the left-view image and the right-view image of an undistorted stereo image in DCT domain and embedding digital watermarking obtained by processing quantization coding on the characteristics into the DCT domain; at a receiving terminal, detecting the digital watermarking embedded in the distorted stereo image and processing decoding and inverse quantization to extract the embedded characteristics of the left-view image and the right-view image of the stereo image, obtaining a stereo perception value and a view quality value of the distorted stereo image according to the embedded characteristics, and finally obtaining an objective quality score of the distorted stereo image utilizing a support vector regression model. | 04-02-2015 |
Patent application number | Description | Published |
20120238991 | Pump Activated Pinch Clamp - A system for controlling flow of a fluid in a tube with a controlling device includes a pinch clamp. The pinch clamp has a first leg, a second leg, a connecting region there between, a pinching region, and a first part of a quick release connector. The first leg and the second leg are both connected to the connecting region. Whether the pinching region is in an open position or in a closed position is determined by spacing between the first leg and the second leg. The first leg includes the first part of the quick release connector. The first part of the quick release connector includes an element for quickly mounting the pinch clamp to the controlling device and for quickly dismounting the pinch clamp from the controlling device. | 09-20-2012 |
20120283630 | Flow Control Line Management Apparatus - A line management apparatus for managing multiple IV lines connected in a Y fitting or multi-way fitting provides for flow sensing and for electronic control of flow in the multiple lines. The line management apparatus may be used independently as a precise gravity feed IV system or may provide for use in combination with an infusion pump to ensure proper delivery of multiple solutions without blending of the two. | 11-08-2012 |
20120310205 | Medical Pump Providing Customizable Programming Permissions - A method and apparatus for delivering intravenous drugs to a patient provides for remote loading and programming of IV pumps that may be shipped in a loaded and programmed configuration to a remote site for use with the patient. A special carrier may be provided for pneumatic delivery of the preloaded pump. Password enabled customizing of pump features according to specific user's need may be provided to prevent undesired changing of the pump parameters at the remote site. | 12-06-2012 |
20120323170 | System for Programming Medical Pumps with Reduced-Error - Medical pumps may obtain programming data from a database through the use of a remote query process which allows the individual pump to flexibly request data from existing hospital databases, to identify the necessary information in those databases, and to convert that data for use without the need for manual programming or a centralized pump control system. | 12-20-2012 |
20130144206 | Medical Device With Contextual Awareness - A medical device, such as an infusion pump, obtains a contextual awareness of its operation by communicating with centralized patient records and or other medical equipment communicating with a common patient, and/or provides real time advisory information, at care point or remotely. A protocol obtained by the medical device from a protocol server provides context-aware protocols and necessary predicate information for those protocols. This predicate information may be discovered by the medical device communicating with electronic medical records and the associated medical equipment. | 06-06-2013 |
20140114238 | SYRINGE PUMP WITH IMPROVED FLOW MONITORING - A syringe pump provides a controlled metering of the medicament from a syringe by movement of the syringe plunger while also measuring flow from the syringe with a flow sensor. Simultaneous monitoring of flow command implicit in control of the syringe plunger and an actual flow provides additional safety and detection of irregularities in the delivery of the medicament. | 04-24-2014 |
20140171868 | Multifunction Capacitive Sensor for Medical Pump - A medical pump or the like provides for a multi-function flow monitor that provides for capacitive plates positioned on opposite sides of the IV line to sense changes in the electrical environment within the IV line to deduce IV line pressure, the presence of IV fluid bubbles, the presence of the IV line within the pump, and/or correct pump operation. Each of these conditions may be determined by different analysis of the capacitance across the capacitive plates. | 06-19-2014 |
20140171869 | Flow Sensor for Medical Pump - A medical pump or the like provides a flow sensor element that may be integrated into the IV tubing assembly. The flow sensor element tits within the medical pump which may provide for capacitive plates sensing changes in the electrical environment within the flow sensor element to deduce flow. For example, the flow sensor element may promote free space liquid drops that cause a periodic change in capacitance across the flow sensor element or the flow sensor element may hold a physical turbine or the like whose movement changes the capacitance across the capacitive plates. | 06-19-2014 |
20140194817 | MEDICAL PUMP WITH OPERATOR-AUTHORIZATION AWARENESS - A medical pump for delivering medicament through an IV line to a patient may provide for awareness of the operator and operator authority limiting access by any individual to particular tasks of procedure review, pump programming, pump loading, patient set up, pump operation, and the like associated with the treatment provided by the medical pump. Identifying the operator allows the assignment of particular authority levels to the operators to ensure proper operation of the medical pump, and/or proper operators have made the necessary review to perform the necessary set up of the medical pump facilitating collaborative healthcare delivery. A record of operator intervention and authority levels may be logged to permit an automatic checklist process by the medical pump. Authentication process and pump operation parameters can be communicated through Near Field Communication (NFC). | 07-10-2014 |
20160058940 | LOW-COST AMBULATORY MEDICAL PUMP - A low-cost medical pump for ambulatory use provides reduced life components combined with a pump lockout enforcing a safe operating limit and preventing reuse after that limit is exceeded. An improved IV line clamp portion minimizes unsupported clamp structure length and provides a dual lock system preventing inadvertent clamp release. | 03-03-2016 |
20160058943 | Flow Sensor for Medical Pump - A medical pump or the like provides a flow sensor element that may be integrated into the IV tubing assembly. The flow sensor element fits within the medical pump which may provide for capacitive plates sensing changes in the electrical environment within the flow sensor element to deduce flow. For example, the flow sensor element may promote free space liquid drops that cause a periodic change in capacitance across the flow sensor element or the flow sensor element may hold a physical turbine or the like whose movement changes the capacitance across the capacitive plates. | 03-03-2016 |
20160061881 | Smart Junction Box for Photovoltaic Systems - A “smart” junction box for photovoltaic systems provides electrical measurements of strings of photovoltaic cells to detect premature photovoltaic cell degradation, bypass diode failure, and arcing, and report the same to a central location and/or to provide for automatic disconnection of a given string of photovoltaic cells. The smart junction box also provides general reporting of electrical characteristics to the central system and allows disconnection by command from the central system. | 03-03-2016 |
20160136354 | Multifunction Capacitive Sensor for Medical Pump - A medical pump or the like provides for a multi-function flow monitor that provides for capacitive plates positioned on opposite sides of the IV line to sense changes in the electrical environment within the IV line to deduce IV line pressure, the presence of IV fluid bubbles, the presence of the IV line within the pump, and/or correct pump operation. Each of these conditions may he determined by different analysis of the capacitance across the capacitive plates. | 05-19-2016 |
Patent application number | Description | Published |
20090319947 | MOBILE COMMUNICATION DEVICE WITH GRAPHICAL USER INTERFACE TO ENABLE ACCESS TO PORTAL SERVICES - Systems, methods, and devices for accessing portal services via a mobile communication device are provided. The mobile communication device may execute a menu program having a graphical user interface. The graphical user interface may include a service menu screen including a plurality of service selectors, each service selector having a respective service icon positioned within a boundary, the service icon graphically representing a service of a communications portal with which the mobile communication device is configured to communicate. Each respective service icon may be selectable by a user to access a corresponding client program of the associated service served by the communications portal. At least some of the service selectors may further include a shared status icon indicating an operational state of the service and/or associated client program. | 12-24-2009 |
20120292711 | SEMICONDUCTOR STRUCTURE AND METHOD FOR FORMING THE SAME - A semiconductor structure is provided. The semiconductor structure comprises: a substrate; a gate dielectric layer formed on the substrate; a metal gate electrode layer formed on the gate dielectric layer; and at least one metal-containing adjusting layer for adjusting a work function of the semiconductor structure, in which an interfacial layer is formed between the substrate and the gate dielectric layer, and an energy of bond between a metal atom in the metal-containing adjusting layer and an oxygen atom is larger than that between an atom of materials forming the gate dielectric layer or the interfacial layer and an oxygen atom. Further, a method for forming the semiconductor structure is also provided. | 11-22-2012 |
20130200444 | SCHOTTKY BARRIER FIELD EFFECT TRANSISTOR WITH CARBON-CONTAINING INSULATION LAYER AND METHOD FOR FABRICATING THE SAME - A Schottky barrier field effect transistor with a carbon-containing insulation layer and a method for fabricating the same are provided. The Schottky barrier field effect transistor comprises: a substrate; a gate stack formed on the substrate; a metal source and a metal drain formed in the substrate on both sides of the gate stack respectively; and the carbon-containing insulation layer formed between the substrate and the metal source and between the substrate and the metal drain respectively, in which a material of the carbon-containing insulation layer is organic molecular chains containing an alkyl group. | 08-08-2013 |
20130277677 | METHOD FOR FORMING POLYCRYSTALLINE FILM, POLYCRYSTALLINE FILM AND THIN FILM TRANSISTOR FABRICATED FROM THE POLYCRYSTALLINE FILM - A method for forming a polycrystalline film, a polycrystalline film formed by the method and a thin film transistor fabricated from the polycrystalline film are provided. The method comprises the steps of: providing a substrate; forming a thermal conductor layer on the substrate; etching the thermal conductor layer until the substrate is exposed to form a thermal conductor pattern; forming a seed layer on the thermal conductor layer and the substrate; etching the seed layer to form seed crystals on both sidewalls of the thermal conductor; forming an amorphous layer on the substrate, the thermal conductor layer and the seed crystals; etching the amorphous layer; and recrystallizing the amorphous layer to form a polycrystalline layer. | 10-24-2013 |
20140291727 | METHOD FOR FORMING SEMICONDUCTOR GATE STRUCTURE AND SEMICONDUCTOR GATE STRUCTURE - A method for forming a semiconductor gate structure and a semiconductor gate structure are provided. The method includes: providing a substrate with a Ge layer as a surface thereof; forming a Sn layer on the Ge layer, in which an interface between the Ge layer and the Sn layer is a GeSn layer; removing the Sn layer to expose the GeSn layer; forming a GeSnO | 10-02-2014 |
20150243502 | METHOD FOR FORMING FIN FIELD EFFECT TRANSISTOR - A method for forming a fin field effect transistor is provided. The method includes: providing a substrate; forming a fin structure with a material Ge or GeSi on the substrate; implanting atoms, molecules, ions or plasmas containing an element Sn into the fin structure with the material Ge or GeSi to form a Ge-based GeSn layer or a Ge-based GeSnSi layer; and forming a gate stack on the Ge-based GeSn layer or the Ge-based GeSnSi layer, the gate stack being oriented transversely to the fin structure. | 08-27-2015 |
20150243505 | METHOD FOR FORMING FIN FIELD EFFECT TRANSISTOR - A method for forming a FinFET is provided, comprising: providing a substrate; forming a fin structure with a material Ge or GeSi on the substrate; forming a gate stack or a dummy gate on the substrate; defining a first region and a second region in the fin structure; and implanting atoms, molecules, ions or plasmas containing an element Sn into the first region and the second region in the fin structure with the material Ge to form a strained GeSn layer, or implanting atoms, molecules, ions or plasmas containing an element Sn into the first region and the second region in the fin structure with the material GeSi to form a strained GeSnSi layer, or co-implanting atoms, molecules, ions or plasmas containing elements Sn and Si into the first region and the second region in the fin structure with the material GeSi to form a strained GeSnSi layer. | 08-27-2015 |
20150243506 | METHOD FOR FORMING GERMANIUM-BASED LAYER - A method for forming a germanium-based layer is provided. The method includes: providing a substrate having a Ge or GeSi surface layer; and implanting atoms, molecules, ions or plasmas containing an element Sn into the Ge surface layer to form a Ge-based GeSn layer, or implanting atoms, molecules, ions or plasmas containing an element Sn into the GeSi surface layer to form a Ge-based GeSnSi layer, or co-implanting atoms, molecules, ions or plasmas containing elements Sn and Si into the Ge surface layer to form a Ge-based GeSnSi layer. | 08-27-2015 |