Patent application number | Description | Published |
20100042351 | METHODS AND APPARATUS RELATED TO MANAGEMENT OF EXPERIMENTS - In one embodiment, a method includes sending an indicator of an availability of a sample from a sample pool stored in a physical inventory. The sample being included in the sample pool based on an attribute of the sample satisfying a condition associated with the sample pool. An indicator that the sample has been selected from the sample pool for analysis at a first test site included in an array of test sites is received. A rule is retrieved from a rule database based on an experimental parameter value associated with the first test site. At least one of the experimental parameter value associated with the first test site or an experimental parameter value associated with a second test site is modified based on a condition within the rule being satisfied. | 02-18-2010 |
20110104717 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 05-05-2011 |
20110269154 | Methods for Diagnosis, Prognosis and Methods of Treatment - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 11-03-2011 |
20120215481 | METHODS AND APPARATUS RELATED TO MANAGEMENT OF EXPERIMENTS - In one embodiment, a method includes sending an indicator of an availability of a sample from a sample pool stored in a physical inventory. The sample being included in the sample pool based on an attribute of the sample satisfying a condition associated with the sample pool. An indicator that the sample has been selected from the sample pool for analysis at a first test site included in an array of test sites is received. A rule is retrieved from a rule database based on an experimental parameter value associated with the first test site. At least one of the experimental parameter value associated with the first test site or an experimental parameter value associated with a second test site is modified based on a condition within the rule being satisfied. | 08-23-2012 |
20130034862 | Methods for Diagnosis, Prognosis and Methods of Treatment - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 02-07-2013 |
20130035253 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. | 02-07-2013 |
20140017678 | PATHWAY CHARACTERIZATION OF CELLS - The present invention provides methods, compositions and kits for the characterization of cellular pathways in cells containing genetic alterations. | 01-16-2014 |
20140147857 | METHODS FOR DIAGNOSIS PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 05-29-2014 |
20140199273 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell population. | 07-17-2014 |
20150017119 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 01-15-2015 |
20150119288 | KITS FOR MULTIPARAMETRIC PHOSPHO ANALYSIS - As disclosed herein, the present invention provides for kits and a composition for diagnosis, prognosis, drug discovery, drug development, and patient stratification. The kits can comprise a plurality of binding elements for cell surface markers, and a plurality of binding elements for state-specific intracellular markers. The kits can further comprise a plurality of modulators directed for the particular cell function or signaling pathways. The kits can further include fixatives, permeabilizing agent, buffers, containers, instructions, and software for data analysis/compilation. | 04-30-2015 |
Patent application number | Description | Published |
20100009364 | Methods for diagnosis, prognosis and methods of treatment - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 01-14-2010 |
20130130279 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. | 05-23-2013 |
Patent application number | Description | Published |
20100032116 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 02-11-2010 |
20120055645 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 03-08-2012 |
20120058274 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 03-08-2012 |
20130192777 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 08-01-2013 |
20130192781 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 08-01-2013 |
20140338561 | BUILDING MATERIAL FOR FORMING AN ARCHITECTURAL SURFACE COVERING AND METHOD FOR PRODUCING THE SAME - A building material for use in forming exterior surface coverings. According to a preferred embodiment, the building material consists of the combination of a paper material, bonding agent, and water. The building material can either be formed directly upon a substrate, such as a wall or ceiling, or otherwise formed as a sheet of material or molding that can thereafter be affixed to a given surface or substrate. The building materials can be customized to have a specific type of color, shape and texture, and can further be utilized in a wide variety of building applications. | 11-20-2014 |
Patent application number | Description | Published |
20100034123 | SETTING UP A FULL-DUPLEX COMMUNICATION SESSION AND TRANSITIONING BETWEEN HALF-DUPLEX AND FULL-DUPLEX DURING A COMMUNICATION SESSION WITHIN A WIRELESS COMMUNICATIONS SYSTEM - In an embodiment, an originating device sends a request, to a server, to initiate a full-duplex session with a target device. Responsive to the full-duplex request, a half-duplex session is set-up from the originating device to the target device before the full-duplex session is set-up. The target device indicates its acceptance of the half-duplex session, receives half-duplex media from the originating device and selectively indicates its acceptance of the full-duplex session. In another embodiment, during a session currently supported either by half-duplex or full-duplex, the server arbitrating the session receives a request from one of the session participants to transition the session to another duplex-type. The server then selectively transitions the duplex-type of the session. | 02-11-2010 |
20130315110 | SETTING UP A FULL-DUPLEX COMMUNICATION SESSION AND TRANSITIONING BETWEEN HALF-DUPLEX AND FULL-DUPLEX DURING A COMMUNICATION SESSION WITHIN A WIRELESS COMMUNICATIONS SYSTEM - In an embodiment, an originating device sends a request, to a server, to initiate a full-duplex session with a target device. Responsive to the full-duplex request, a half-duplex session is set-up from the originating device to the target device before the full-duplex session is set-up. The target device indicates its acceptance of the half-duplex session, receives half-duplex media from the originating device and selectively indicates its acceptance of the full-duplex session. In another embodiment, during a session currently supported either by half-duplex or full-duplex, the server arbitrating the session receives a request from one of the session participants to transition the session to another duplex-type. The server then selectively transitions the duplex-type of the session. | 11-28-2013 |
20140051474 | METHOD AND APPARATUS FOR ESTABLISHING AN INVITE-FIRST COMMUNICATION SESSION - The disclosed embodiments provide methods and apparatus for establishing an invite-first communication session in a wireless communication network. The method includes receiving an invite message from an inviter, forwarding the invite message to at least one invitee, receiving a response from one of the at least one invitee in response to the invite message, and establishing the communication session between the inviter and the at least one invitee. | 02-20-2014 |
Patent application number | Description | Published |
20080318563 | SYSTEM AND METHOD FOR USER PROFILING FROM GATHERING USER DATA THROUGH INTERACTION WITH A WIRELESS COMMUNICATION DEVICE - A system, method, and wireless communication device that profiles a user thereof, or a user at a second wireless communication device in communication therewith. The wireless communication device gathers user data for a user thereof, or from a user at a second wireless communication device, and either directly generates, or has generated elsewhere, a user profile, such as a personality or psychological profile, or medical diagnosis of the user, and can display the user profile to the user and/or alter the wireless communication device functionality based upon the user profile. The gathered user data can be from physical user interaction with the wireless communication device, or from other equipment resident at the wireless communication device, such as a camera and medical diagnostic devices. | 12-25-2008 |
20080318610 | SYSTEM AND METHOD FOR SHARING MEDIA IN A GROUP COMMUNICATION AMONG WIRELESS COMMUNICATION DEVICES - A system, method, and wireless communication device for sharing media in a group communication among a plurality of wireless communications devices, such as among a Push-to-Talk (PTT) group. A wireless communication device that is a member of the communication group can send group-directed media, such as graphics, multimedia and applications, to other members of the communication group, either during a ongoing PTT communication, or independently therefrom. In one embodiment, a group communication computer device stores information on communication groups on the wireless communication network that includes the member wireless communication devices of one or more communication groups, and receives group-directed media from a sending wireless communication device sends the group-directed media either directly to the other member wireless communication devices of the communication group or stores the group-directed media such that the other member devices can access and download the group-directed media. | 12-25-2008 |
20090280834 | SYSTEM AND METHOD FOR RAN ASSISTED LOCATION UPDATE - An apparatus and method for efficiently updating location information of a mobile device in a wireless communication network, such as a cellular network, is disclosed. The mobile device sends a location message over an access channel. The wireless communication device continually transmits a location message at periodic intervals regards of the status of the base station in communication with the wireless communication device. The base station determines a timeslot in which to receive a location message transmitted by the wireless communication device. If more than one wireless communication device is transmitting a location message, the base station prioritizes the order in which to receive the location message, opening the first available timeslot to the higher priority wireless communication device. A high priority device may be a wireless communication device used by emergency services personnel, such as firefighters or the police. | 11-12-2009 |
20140321393 | QUALITY OF SERVICE (QoS) ACQUISITION AND PROVISIONING WITHIN A WIRELESS COMMUNICATIONS SYSTEM - In an embodiment, an access network (AN) receives a message configured to prompt a conditional allocation of Quality of Service (QoS) resources to an access terminal (AT). The message can be received from the AT or from an application server (AS) that arbitrates a communication session for the AT. In another embodiment, if the AT determines that a QoS resource request has not yet been granted, the AT waits until the traffic channel (TCH) has been obtained for a communication session before resending the QoS resource request. In another embodiment, if the AT determines to initiate or join a second communication session before a confirmation that QoS resources for a first communication session are relinquished, the AT waits until the confirmation is received before a request for QoS resources for the second communication session is sent. | 10-30-2014 |
Patent application number | Description | Published |
20120149360 | SYSTEM AND METHOD FOR USER PROFILING FROM GATHERING USER DATA THROUGH INTERACTION WITH A WIRELESS COMMUNICATION DEVICE - A system, method, and wireless communication device that profiles a user thereof, or a user at a second wireless communication device in communication therewith. The wireless communication device gathers user data for a user thereof, or from a user at a second wireless communication device, and either directly generates, or has generated elsewhere, a user profile, such as a personality or psychological profile, or medical diagnosis of the user, and can display the user profile to the user and/or alter the wireless communication device functionality based upon the user profile. The gathered user data can be from physical user interaction with the wireless communication device, or from other equipment resident at the wireless communication device, such as a camera and medical diagnostic devices. | 06-14-2012 |
20120149993 | SYSTEM AND METHOD FOR USER PROFILING FROM GATHERING USER DATA THROUGH INTERACTION WITH A WIRELESS COMMUNICATION DEVICE - A system, method, and wireless communication device that profiles a user thereof, or a user at a second wireless communication device in communication therewith. The wireless communication device gathers user data for a user thereof, or from a user at a second wireless communication device, and either directly generates, or has generated elsewhere, a user profile, such as a personality or psychological profile, or medical diagnosis of the user, and can display the user profile to the user and/or alter the wireless communication device functionality based upon the user profile. The gathered user data can be from physical user interaction with the wireless communication device, or from other equipment resident at the wireless communication device, such as a camera and medical diagnostic devices. | 06-14-2012 |
20120157075 | SYSTEM AND METHOD FOR USER PROFILING FROM GATHERING USER DATA THROUGH INTERACTION WITH A WIRELESS COMMUNICATION DEVICE - A system, method, and wireless communication device that profiles a user thereof, or a user at a second wireless communication device in communication therewith. The wireless communication device gathers user data for a user thereof, or from a user at a second wireless communication device, and either directly generates, or has generated elsewhere, a user profile, such as a personality or psychological profile, or medical diagnosis of the user, and can display the user profile to the user and/or alter the wireless communication device functionality based upon the user profile. The gathered user data can be from physical user interaction with the wireless communication device, or from other equipment resident at the wireless communication device, such as a camera and medical diagnostic devices. | 06-21-2012 |
Patent application number | Description | Published |
20080205116 | THREE-DIMENSIONAL MAGNETIC MEMORY - Magnetic memories and methods are disclosed. A magnetic memory as described herein includes a plurality of stacked data storage layers to form a three-dimensional magnetic memory. Bits may be written to a data storage layer in the form of magnetic domains. The bits can then be transferred between the stacked data storage layers by heating a neighboring data storage layer, which allows the magnetic fields from the magnetic domains to imprint the magnetic domains in the neighboring data storage layer. By imprinting the magnetic domains into the neighboring data storage layer, the bits are copied from one data storage layer to another. | 08-28-2008 |
20100002487 | THREE-DIMENSIONAL MAGNETIC MEMORY - Magnetic memories and methods are disclosed. A magnetic memory as described herein includes a plurality of stacked data storage layers to form a three-dimensional magnetic memory. Bits may be written to a data storage layer in the form of magnetic domains. The bits can then be transferred between the stacked data storage layers by heating a neighboring data storage layer, which allows the magnetic fields from the magnetic domains to imprint the magnetic domains in the neighboring data storage layer. By imprinting the magnetic domains into the neighboring data storage layer, the bits are copied from one data storage layer to another. | 01-07-2010 |
20100091408 | HARD DISK DRIVE WITH DISK SEPARATOR FOR CREATING AXIAL GAPS BETWEEN DISKS FOR ACCESS BY READ/WRITE HEADS - A hard disk drive (HDD) has a stack of disks mounted on a rotatable spindle with the disks being movable axially, i.e., in a direction parallel to the axis of rotation of the spindle. A disk separator is located inside the spindle and separates axially-adjacent disks in a pair to create an axial gap. Any pair of axially-adjacent disks can be separated so that different axial gaps are created. A single head-arm assembly with at least one and preferably two read write heads is movable axially so that it can be rotated by the rotary actuator into any one of the axial gaps. The read/write heads can thus access data on the disk surfaces in the axial gaps. When it is desired to have the disk separator create an new axial gap and thus a new pair of disk surfaces to be accessed, the actuator rotates the head-arm assembly away from the outer perimeters of the disks and moves the read/write heads onto a head support structure that supports the read/write heads off the disks. | 04-15-2010 |
20110069413 | CURRENT-PERPENDICULAR-TO-THE-PLANE (CPP) MAGNETORESISTIVE READ HEAD WITH MULTIPLE SENSING ELEMENTS FOR PATTERNED-MEDIA - A magnetoresistive (MR) sensor or read head for a magnetic recording disk drive has multiple independent current-perpendicular-to-the-plane (CPP) MR sensing elements. The sensing elements are spaced-apart in the cross-track direction and separated by an insulating separation region so as to be capable of reading data from multiple data tracks on the disk. The sensing elements have independent CPP sense currents, each of which is directed to independent data detection electronics, respectively. Each sensing element comprises a stack of layers formed on a common electrically conducting base layer, which may be a bottom magnetic shield layer formed of electrically conducting magnetically permeable material. Each sensing element has a top electrical lead layer. A top magnetic shield layer is located above the sensing elements in contact with the top lead layers. The top shield layer is formed of soft magnetically permeable material, but is electrically insulating, so that the independent sense currents can be passed to the independent sensing elements. | 03-24-2011 |
20110143169 | PERPENDICULAR MAGNETIC RECORDING DISK WITH ORDERED NUCLEATION LAYER AND METHOD FOR MAKING THE DISK - A continuous-media perpendicular magnetic recording disk with an oxide-containing granular Co alloy recording layer (RL) having minimal grain size dispersion has an ordered nucleation layer (ONL) formed below RL. The ONL has ordered nucleation sites arranged in a generally repetitive pattern. The nucleation sites are generally surrounded by non-nucleation regions of a different material than the nucleation sites. The Co-alloy grains of the subsequently deposited RL grow on the nucleation sites and the oxide of the RL become generally segregated on the non-nucleation regions. The ordered nucleation sites may be formed of a Ru-containing material and the non-nucleation regions may be formed of an oxide. The ONL is formed by nanoimprint lithography, preferably by a master mold fabricated with a method using self-assembling block copolymers for creating periodic nanometer scale features. | 06-16-2011 |
20120250178 | MAGNETIC MEDIA WITH THERMAL INSULATION LAYER FOR THERMALLY ASSISTED MAGNETIC DATA RECORDING - A magnetic media for heat assisted magnetic data recording. The magnetic media includes a thermal insulation layer structure formed near the substrate of the media provide more efficient heating of the write layer by allowing less heat dissipation to the substrate. The thermal insulation layer structure can be one or more layers of an oxide such as SiO2 and one or more layers of a material such as NiTa. Increasing the number of oxide layers and NiTa layers increases the thermal insulation of the thermal insulation layer structure thereby further increasing the efficiency of the heat assisted writing. | 10-04-2012 |
20130028061 | SHINGLED-WRITING THERMAL ASSISTANCE RECORDING (TAR) DISK DRIVE WITH AVOIDANCE OF ADJACENT TRACK ERASURE FROM A WIDE-AREA HEATER - A thermally-assisted recording (TAR) disk drive that uses “shingled” recording and a rectangular waveguide as a “wide-area” heat source includes a controller that counts the number of writes to each annular band of data tracks. The wide-area heater generates a heat spot that extends across multiple tracks, so that each time an annular band is written, the data in tracks in adjacent bands are also heated. Because the bands are written independently, the number of passes of the heat spot and thereby the number of times the data tracks in a band are exposed to elevated temperatures without being re-written is related to the number of re-writes of the adjacent bands. The number of writes to each band is counted and when that count reaches a predetermined threshold value, one or more tracks in an adjacent band are re-written to avoid reaching an unacceptable level of magnetization decay in the tracks of the adjacent band. | 01-31-2013 |
Patent application number | Description | Published |
20130122116 | PAIN RELIEVER COMPOSITION - A pain reliever comprised of dextrose, aloe vera concentrate, and some or all of the following ingredients: propylene glycol, caprylic/capric tryglicerides, sodium chloride (or acetic acid), a homeopathic anti-inflammatory extract, Dimethyl Sulfone (or Methylsulfonylmethane (MSM)), cetyl myristoleate, and a pitcher plant extract. The resulting compositions are a water-based solution and two gel composition applied to the epidermis of mammals for relieving pain. | 05-16-2013 |
20130236530 | PAIN RELIEVER COMPOSITION - A pain reliever comprised of dextrose, | 09-12-2013 |
20130236577 | PAIN RELIEVER COMPOSITION - A pain reliever comprised of dextrose, aloe vera concentrate, and some or all of the following ingredients: propylene glycol, caprylic/capric tryglicerides, sodium chloride (or acetic acid), a homeopathic anti-inflamatory extract, Dimethyl Sulfone (or Methylsulfonylmethane (MSM)), cetyl myristoleate, and, optionally, a pitcher plant extract. The resulting compositions are a water-based solution and two gel composition applied to the epidermis of mammals for relieving pain. | 09-12-2013 |
20140271828 | Pain Reliever Composition - A pain reliever comprised of dextrose, aloe vera concentrate, and some or all of the following ingredients: propylene glycol, caprylic/capric tryglicerides, sodium chloride (or acetic acid), a homeopathic anti-inflamatory extract, Dimethyl Sulfone (or Methylsulfonylmethane (MSM)), cetyl myristoleate, and, optionally, a pitcher plant extract. The resulting compositions are a water-based solution and two gel composition applied to the epidermis of mammals for relieving pain. | 09-18-2014 |
Patent application number | Description | Published |
20090253717 | Inhibitors of p97 - One aspect of the invention relates to compounds that inhibit the activity of p97, such as by binding covalently to a cysteine residue in the active site. In certain embodiments, the invention relates to the treatment of disease, such as cancer, comprising administering a compound of the invention. | 10-08-2009 |
20100010001 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS - Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-4-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. | 01-14-2010 |
20120329838 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS - Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. | 12-27-2012 |
20120329839 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS - Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. | 12-27-2012 |
20150057307 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS - Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. | 02-26-2015 |
Patent application number | Description | Published |
20110020779 | SKILL EVALUATION USING SPHERICAL MOTION MECHANISM - Software tools, methods and apparatus for objectively assessing surgical and medical procedural skills are described. Data corresponding to performance of a manipulative task by a subject is modeled using Markov modeling techniques and compared with stored models corresponding to each of a plurality of proficiency levels. A particular proficiency level is selected based on proximity of the subject data relative to each of the stored models. | 01-27-2011 |
20110118543 | SURGICAL DEVICE - A surgical device comprises an external sheath having a proximal end and a distal end for insertion through an opening of a body and a plurality of tool components extending from the distal end of the external sheath. The tool components are independently deflectable with respect to each other and with respect to the external sheath and removable from the device without requiring withdrawal of the sheath through the opening of the body. The external sheath is flexible and deflectable intermediate the distal and proximal ends. This permits the device to be steered in a curvilinear manner towards a surgical target. | 05-19-2011 |
20110238079 | Surgical Cockpit Comprising Multisensory and Multimodal Interfaces for Robotic Surgery and Methods Related Thereto - Local surgical cockpits comprising local surgical consoles that can communicate with any desired remote surgical module (surgical robot), for example via a shared Transmission Control Protocol/Internet Protocol (TCP/IP) or other unified open source communication protocol or other suitable communication system. The systems and methods, etc., herein can also comprise a modular approach wherein multiple surgical consoles can network supporting collaborative surgery regardless of the physical location of the surgeons relative to each other and/or relative to the surgical site. Thus, for example, an operator operating a local surgical cockpit can teleoperate using a remote surgical module on a patient in the same room as the surgeon, or surgeons located in multiple safe locations can telemanipulate remote multiple surgical robots on a patient in or close to a war zone. | 09-29-2011 |
20110257672 | INTRODUCER DEVICE - An introducer and method provides a surgical tool with a pathway through tissue to a surgical site, wherein the surgical tool includes at least one surgical instrument. The introducer comprises a flexible sheath having a distal portion including a distal end and is arranged for receiving the surgical tool. A tissue separation tip at the distal portion of the sheath advances the sheath into the tissue towards the surgical site. The tissue separation tip is arranged to form a tissue gap and provide the at least one surgical instrument access to the tissue gap for performing a medical procedure consonant with the formation of the tissue gap or the performance of work at the surgical site. | 10-20-2011 |
20120203069 | SURGICAL SHIELD FOR SOFT TISSUE PROTECTION - A soft tissue protection surgical shield protects collateral soft tissue from damage during a surgical procedure within a surgical space of a body. The shield comprises an elongated flexible shield having a proximal end and a distal end. The proximal end has a first opening and the distal end has a second opening. The shield further comprises a side wall between the proximal and distal ends that defines the first and second openings. The side wall is conformal to the surgical space and arranged to resist perforation by surgical instruments in use during the surgical procedure, and also to define and maintain the access pathway to the surgical site. | 08-09-2012 |
20140114338 | INTRODUCER DEVICE - An introducer and method provides a surgical tool with a pathway through tissue to a surgical site, wherein the surgical tool includes at least one surgical instrument. The introducer comprises a flexible sheath having a distal portion including a distal end and is arranged for receiving the surgical tool. A tissue separation tip at the distal portion of the sheath advances the sheath into the tissue towards the surgical site. The tissue separation tip is arranged to form a tissue gap and provide the at least one surgical instrument access to the tissue gap for performing a medical procedure consonant with the formation of the tissue gap or the performance of work at the surgical site. | 04-24-2014 |
20140155910 | Spherical Motion Mechanism - This document discusses, among other things, a mechanism for providing motion having two degrees of freedom and centered on a single point within a sphere. Methods to design the mechanism consistent with specified parameters are also described. | 06-05-2014 |
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Patent application number | Description | Published |
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20100065721 | Enhanced glare reduction - The driver of a vehicle ( | 03-18-2010 |
20100176129 | Enhanced container system - Food containers formed of sheet plastic are latchably stackable on one another. Each container has base ( | 07-15-2010 |
20100276422 | ENHANCED SECURE CONTAINER - A container of sheet plastic reveals when it has been opened after a clerk loaded it with food. The container has a base ( | 11-04-2010 |
20120241456 | Containers with tamper-evident features - A container has a lid that can be opened only by lifting and pulling a pull tab, with lifting of the pull tab resulting in an evident change. The pull tab is held down by attachment (interference fit, weld, glue) to a lid surface by a hold-down that is joined to the pull tab by a pair of bridges. When the pull tab is lifted, the bridges are broken. Thereafter, the pull tab springs up slightly from the lid plane, under the force of one or more spring walls and a hinge, which makes it evident that the container has been opened. | 09-27-2012 |
Patent application number | Description | Published |
20100204226 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS - Quinazolinone compounds of formula (I) are described, | 08-12-2010 |
20110046132 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS - The present invention is directed to benzoimidazole compounds of the formula (1) and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions modulated by prolyl hydroxylase activity. | 02-24-2011 |
20130143871 | 4-AMINOQUINAZOLIN-2-YL-1-PYRRAZOLE-4-CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS - Aminoquinazolinyl compounds of formula (I) are described, which are useful as prolyl hydroxylase inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by prolyl hydroxylase activity. Thus, the compounds may be administered to treat, e.g., anemia, vascular disorders, metabolic disorders, and wound healing. | 06-06-2013 |
20140005193 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | 01-02-2014 |
20140221310 | FLAP MODULATORS - The present invention relates to compounds of Formula (I), | 08-07-2014 |
20140221311 | FLAP MODULATORS - The present invention relates to compounds of Formula (I), | 08-07-2014 |
20140256722 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS - The present invention is directed to benzoimidazole compounds of the formula: | 09-11-2014 |
20140309215 | 4-AMINOQUINAZOLIN-2-YL-1-PYRRAZOLE-4-CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS - Aminoquinazolinyl compounds of formula (I) are described, | 10-16-2014 |
Patent application number | Description | Published |
20100245162 | AGILE BEAM PULSE TO PULSE INTERLEAVED RADAR MODES - A system and method for concurrently operating a plurality of agile beam radar modes by pulse-to-pulse interleaving groups of the radar modes. Radar modes are grouped, each radar mode being allocated a certain amount of time for operation and a suitable pulse repetition frequency to improve or optimize the duty cycle of the antenna while concurrently operating the plurality of modes. Priorities may be assigned to groups or to individual radar modes within each group. In some embodiments, TDM communications are further interleaved within the radar modes to enhance the operation of the radar antenna. | 09-30-2010 |
20130093617 | METHODS FOR RESOLVING RADAR AMBIGUITIES USING MULTIPLE HYPOTHESIS TRACKING - Methods for resolving radar ambiguities using multiple hypothesis tracking are described. One such method includes (a) choosing a single waveform for each of a plurality of dwells of a first scan, wherein the single waveforms of consecutive scans are different, (b) generating the first scan using the single waveform for each of the dwells of the first scan, (c) receiving observation data as a result of the first scan, the observation data comprising measured positions of true targets and false targets, (d) generating, using multiple hypothesis tracking, position predictions for true targets and false targets, (e) comparing the predicted positions and measured positions, repeating (a)-(e) until a preselected process condition is met, and determining the true targets based on the results of the comparisons. | 04-18-2013 |
20140265674 | ELECTROMECHANICAL FLYWHEEL WITH SAFETY FEATURES - An electromechanical flywheel machine includes multiple enclosures enhancing safe operation of an enclosed motor-generator and flywheel mass. | 09-18-2014 |