Blum, US
Adrienne L. Blum, Denver, CO US
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20140333319 | CHARACTERIZATION OF SUBSTRATE DOPING AND SERIES RESISTANCE DURING SOLAR CELL EFFICIENCY MEASUREMENT - Short-circuit current, maximum power, and open circuit voltage during a single flash are determined by varying intensity, voltage, and current. An apparatus determines the substrate doping and the series resistance of the solar cell. The series resistance of the cell is determined from a voltage step from the maximum power voltage operating point to the open-circuit condition. Methods are described for determining the substrate doping from stepping or sweeping the voltage. The first uses a voltage step and finds the change in charge that results. This determines a unique doping if the series resistance is known. The second uses data for a case of varying current, voltage, and light intensity, and compares this data to the case of varying voltage and intensity with no current. By transposing both cases into the steady state, agreement between the two data sets is found for unique doping and series resistance values. | 11-13-2014 |
Alex E. Blum, Boulder, CO US
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20130004544 | Synthetic Antibacterial Clay Compositions and Method of Using Same - The present invention is directed to synthetic bactericidal compositions having clay like properties and a method of using these compositions to topically treat bactenally-caused skin infections and skin diseases. The compositions within the scope of the invention compnse a bactericidal effective amount of a reducing agent, such as pyπte, marcasite, pyrrhotite, FeS2, FeS, FeS04—or other reducing agents having like properties, and a natural clay or clay mineral and/or synthetic clay or clay mineral, or other suitable matenals having clay-like properties. The synthetic bactericidal compositions are synthesized by adding the reducing agent to the clay or clay mineral. It is the presence of the reducing agent in said compositions that renders them bacteπcidal. The clays serve as a vehicle within which the reducing agent is dispersed, as a diluent to the reducing agent, and also as an adsorbent and low permeability banner in use of the composition | 01-03-2013 |
Amy S. Blum, Washington, DC US
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20080220408 | Protein Scaffolds and Viral Particles For Detecting Analytes - The present invention relates to compositions and methods for detecting analytes using detectably labeled fluorescent protein scaffolds. In certain embodiments of the invention, the scaffolds are viral particles in which the capsid viral structure provides a scaffold to attach detectably labeled fluorescent dyes and capture moieties that can be utilized to determine the presence of a desired analyte in a sample using any suitable method. The protein scaffold can contain amino acids carrying reactive groups (e.g., amines and thiols) that are spatially distributed on it with large enough separation to enable the attachment of a greater number of fluorescent label molecules without quenching | 09-11-2008 |
Andrew Blum, Wilmington, MA US
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20150075261 | METHODS OF DETECTING GLYCOSAMINOGLYCANS - In one aspect, the disclosure provides methods of distinguishing a glycosaminoglycan from one or more other components in a sample by subjecting the sample to size-exclusion chromatography using a mobile phase having a pH of 6.8 or lower. A mobile phase having a pH of 6.8 or lower is found to improve the separation of glycosaminoglycans from proteins during size exclusion chromatography. In some embodiments, improved separation is due to the low pH of the mobile phase causing elution of less dispersed fractions of the protein and/or glycosaminoglycan. In some embodiments, the overlap between protein and/or glycosaminoglycan fractions is reduced. | 03-19-2015 |
Arlin Curtis Blum, Novi, MI US
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20090165356 | Fishing apparatus utilizing remote controlled boat - A fishing apparatus that utilizes a remote controlled boat to remotely deliver the hooked portion of a fishing line to the desired fishing area on the water is disclosed. The remote controlled boat includes a fishing line guide attached thereto. The fishing line guide includes a quick-release attachment portion to which a quick-release pad with fishing line is attached. | 07-02-2009 |
Barak Blum, Chestnut Hill, MA US
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20140287944 | MARKERS FOR FUNCTIONALLY MATURE BETA-CELLS AND METHODS OF USING THE SAME - Markers for functionally mature β-cells and methods of using these markers are disclosed. | 09-25-2014 |
Barak Blum, Allston, MA US
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20120171213 | METHOD OF TREATING TUMORS - A method of reducing the potential of pluripotent stem cells to generate teratomas in a subject is provided. | 07-05-2012 |
Benjamin C. Blum, Brighton, MA US
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20150376229 | TANGENTIAL FLOW FILTRATION BASED PROTEIN REFOLDING METHODS - Provided herein are methods for refolding proteins that are denatured. Exemplary methods comprise solubilizing the denatured protein with a denaturing agent, e.g., a chaotropic agent, and renaturing the protein using a buffer exchanging system, e.g., tangential flow filtration (TFF). | 12-31-2015 |
20160002287 | HIGH PH PROTEIN REFOLDING METHODS - Provided herein are methods for refolding denatured protein (e.g., from inclusion bodies) that do not require the use of a denaturing agent. Exemplary methods use a high pH for solubilizing denatured protein, followed by a decrease in pH for refolding the proteins. | 01-07-2016 |
Bradley J. Blum, Roanoke, VA US
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20090272817 | Method and apparatus for reducing the intensity of hurricanes at sea by deep-water upwelling - Methods and apparatus for reducing the intensity of hurricanes are described herein. A method may include positioning a fleet of submersibles in an area of ocean through which at least a portion of a hurricane's central core will pass within a predetermined amount of time. The submersibles are maneuvered to a depth greater than a depth of a thermocline in this area of ocean. The submersibles maintain their station and depth for a finite amount of time, during which they may release a gas to form bubble plumes which rise toward the ocean's surface. The bubble plumes entrain and upwell cold sub-thermocline water toward the surface of the ocean to cool the surface of the ocean. The cooled ocean surface reduces the intensity of the hurricane whose portion of central core passes through the cooled area. An apparatus to generate a bubble plume may include a gas source, a gas manifold to releasably collect gas from the gas source, and a cover having perforations of a predetermined shape, size, and spacing to produce a predetermined rate of upwelling of seawater. The apparatus may further include a duct to receive at least a portion of the generated bubble plume and channel the cold upwelled seawater toward the surface of the ocean. | 11-05-2009 |
Brian E. Blum, Woodinville, WA US
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20100235494 | FLEXIBLE LOGGING, SUCH AS FOR A WEB SERVER - A flexible logging system is described herein that operates with a web server to provide activity logging in a way that is customizable to include a variety of data fields, can capture both client and server log information to a single location, and can provide data to an analysis engine directly to provide near real-time reporting. The system captures events within the web server as they occur and can provide reporting before the final response occurs. During request processing in the web server, server extension modules raise log events whenever an event occurs. The system matches the received data to a log definition and writes the data to any log that matches. Thus, the flexible logging system provides a rich, flexible, and fast platform for content providers and administrators to get a real-time view of the state of requests to their web servers. | 09-16-2010 |
Carl Stewart Blum, Johns Island, SC US
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20100102011 | CONNECTOR ASSEMBLY - A connector is configured to connect two frame members. The connector includes a body with a first end and a second end spaced from the first end. A fulcrum is coupled to the body between the first end and the second end. The body is configured to be received in a channel of a frame member and pivots about the fulcrum inside the channel between a first pivot position in which the frame members are free to move relative to one another and a second pivot position in which the frame members are locked against relative movement. | 04-29-2010 |
Charles Blum, Cambridge, MA US
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20110319411 | ISOINDOLINONE AND RELATED ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 12-29-2011 |
Charles Blum, Westbrook, CT US
Patent application number | Description | Published |
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20120252780 | BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 10-04-2012 |
Charles A. Blum, Westbrook, CT US
Patent application number | Description | Published |
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20090069347 | 2-phenoxy pyrimidinone analogues - 2-Phenoxy pyrimidinone analogues are provided, of the Formula: | 03-12-2009 |
20100008866 | CIS-CYCLOHEXYL SUBSTITUTED PYRIMIDINONE DERIVATIVES - Cis-cyclohexyl substituted pyrimidinone derivatives are provided, of the Formula: | 01-14-2010 |
20110003813 | SUBSTITUTED BIARYL PIPERAZINYL-PYRIDINE ANALOGUES - Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: | 01-06-2011 |
20120208829 | 2-PHENOXY PYRIMIDINONE ANALOGUES - 2-Phenoxy pyrimidinone analogues are provided, of the Formula: | 08-16-2012 |
Charles A. Blum, Cambridge, MA US
Patent application number | Description | Published |
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20110046110 | QUINOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 02-24-2011 |
20110077248 | IMIDAZOPYRIDINE AND RELATED ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 03-31-2011 |
20110124637 | BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS - Provided herein are sirtuin-modulating compounds of formula (II). The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders relating to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 05-26-2011 |
Charles A. Blum, Waltham, MA US
Patent application number | Description | Published |
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20140249147 | Substituted Bicyclic Aza-Heterocycles and Analogues as Sirtuin Modulators - Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided, are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 09-04-2014 |
20140288052 | SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS - Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 09-25-2014 |
20150057272 | BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 02-26-2015 |
20150152108 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS - The present invention relates to novel substituted bridged urea compounds, corresponding related analogs, pharmaceutical compositions and methods of use thereof. Sirtuin-modulating compounds of the present invention may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders, which include, but are not limited to, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. The present invention also related to compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 06-04-2015 |
20160002273 | THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS - Provided herein are novel substituted thieno[3,2-d]pyrimidine-6-carboxamide sirtuin inhibitors and methods of use thereof. The sirtuin inhibitors may be used for inhibiting a sirtuin-mediated biological process, and, e.g. for treating and/or preventing diseases and disorders including, but not limited to cancer, neurodegenerative disease and inflammation. Also provided herein are pharmaceutical compositions comprising these sirtuin inhibitors and compositions comprising a sirtuin inhibitor in combination with another therapeutic agent. | 01-07-2016 |
20160083386 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS - Provided herein are novel substituted bridged urea and related analogs and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 03-24-2016 |
Craig A. Blum, Freehold, NJ US
Patent application number | Description | Published |
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20100001026 | PISTONS WITH A LIP SEAL AND CARTRIDGE SYSTEMS USING SUCH PISTONS - Pistons for use in a dispensing cartridge, as well as cartridge systems including such pistons. The piston may include a body having a generally cylindrical configuration with a sidewall and a sealing lip extending outwardly from the sidewall. The sealing lip has a first portion dimensioned to have a first flexibility, a second portion dimensioned to have a second flexibility greater than the first flexibility, a sealing edge terminating the second portion, and a sealing bead positioned between the first portion and the sealing edge of the second portion, and the second portion configured to deflect relative to the first portion such that the sealing edge and the sealing bead have a contacting relationship with an inner wall of the cartridge when the piston is inserted into the cartridge. The sealing edge and sealing bead cooperate to prevent leakage during storage and to prevent blow-by during use. | 01-07-2010 |
Daniel Blum, Corvallis, OR US
Patent application number | Description | Published |
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20130251261 | Method And Apparatus For Image Data Compression - A method and corresponding apparatus are for compressing image data of an image. The method includes splitting the image data into regions, including a first region and a second region. The method further includes determining a first compression scheme to be used in encoding the image data of the first region and a different second compression scheme to be used in encoding the image data of the second region. The method further includes applying the first compression scheme to the image data of the first region and the second the compression scheme to the image data of the second region. For each region, the determining and the applying are iteratively performed to yield first resulting compressed region data for the first region and second resulting compressed region data for the second region. | 09-26-2013 |
Darren A. Blum, Naperville, IL US
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20150047331 | HYDRAULIC SYSTEM FOR MACHINE - A hydraulic system for a machine is disclosed. The system includes an actuator configured to move a portion of the machine, a pump configured to supply pressurized fluid to the actuator, an accumulator fluidly coupled to the actuator, a valve arrangement configured to selectively direct the fluid discharged from the actuator to the accumulator for storage and to selectively direct the stored fluid from the accumulator to the actuator, and a controller. The controller is configured to determine an accumulator pressure, an actuator pressure, and an operational parameter associated with an implement system. Further, the controller is configured to determine an accumulator control mode. The controller determines an accumulator pressure leakage rate when the accumulator control mode is neutral. | 02-19-2015 |
Darren Allan Blum, Naperville, IL US
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20140054477 | AXIAL FLUID VALVES WITH ANNULAR FLOW CONTROL MEMBERS - Axial fluid valves having annular flow control members are described herein. An example axial fluid valve described herein includes an axial flow valve body defining a passageway between an inlet and an outlet. The example axial fluid valve includes a sleeve slidably received by an inner surface of the axial flow valve body and movable along an axis substantially parallel to a longitudinal axis of the passageway. The example axial fluid valve includes a linkage or a gear operatively connected to the sleeve to move the sleeve to vary a flow of fluid between the inlet and the outlet through the sleeve. | 02-27-2014 |
20160091110 | AXIAL FLUID VALVES WITH ANNULAR FLOW CONTROL MEMBERS - Axial fluid valves having annular flow control members are described herein. An example axial fluid valve described herein includes an axial flow valve body defining a passageway between an inlet and an outlet. The example axial fluid valve includes a sleeve slidably received by an inner surface of the axial flow valve body and movable along an axis substantially parallel to a longitudinal axis of the passageway. The example axial fluid valve includes a linkage or a gear operatively connected to the sleeve to move the sleeve to vary a flow of fluid between the inlet and the outlet through the sleeve. | 03-31-2016 |
David Blum, Nashville, TN US
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20090155238 | XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature. | 06-18-2009 |
20100003234 | Cellulases, Nucleic Acids Encoding Them and Methods for Making and Using Them - This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. | 01-07-2010 |
20150139977 | XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-glucanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature. | 05-21-2015 |
David Blum, Boston, MA US
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20160048962 | SYSTEM AND METHOD FOR ATLAS REGISTRATION - A system and method for associating anatomically significant regions with regions of one or more images may include automatically modifying images of different modalities according to different correction algorithms, providing a user interface for identifying a plane within three-dimensional data, scaling atlas structures to fit an anatomical image according to identified landmarks, registering an atlas to such an image via a combination of registration algorithms, and/or registering an atlas to such an image using a feature extraction algorithm. | 02-18-2016 |
David Blum, Brentwood, TN US
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20130330783 | CELLULASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. | 12-12-2013 |
20130337507 | Xylanases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature. | 12-19-2013 |
David Arthur Blum, Boston, MA US
Patent application number | Description | Published |
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20090287271 | Clinician programmer system and method for calculating volumes of activation - A system and method for providing a volume of activation (VOA) of a stimulation electrode leadwire may include a processor that calculates a VOA for each of a plurality of sets of parameter settings of the leadwire, stores in a database each of the calculated VOAs in association with the respective set of parameter settings for which it was calculated, obtains a set of parameter settings of the leadwire for a stimulation, and determines a VOA for the obtained set of parameter settings based on the stored VOAs. | 11-19-2009 |
20090287272 | Clinician programmer system and method for steering volumesof activation - A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set. | 11-19-2009 |
20090287273 | Clinician programmer system interface for monitoring patient progress - A therapy tracking system and method may include a processor that obtains physiological information regarding a patient and a time period during which a deep brain stimulation (DBS) therapy is conducted. The information may be organized into a plurality of sessions. The processor may arrange in a display device a separate representation of the information for each of at least a subset of the sessions, such that the sessions are presented in order of time. | 11-19-2009 |
20090287467 | Clinician programmer system and method for generating interface models and displays of volumes of activation - A system and method for displaying a volume of activation (VOA) may include a processor that displays via a display device a model of a portion of a patient anatomy that includes anatomical structures, displays via the display device and overlying the display of the model a VOA associated by the processor with a set of anatomical stimulation parameter settings, the display of the VOA, and graphically identifies interactions between the displayed VOA and a first subset of the anatomical structures associated with one or more stimulation benefits and a second subset of the anatomical structures associated with one or more stimulation side effects, where the graphical identifications differ depending on whether the interaction is with the first subset or the second subset. | 11-19-2009 |
20100049276 | Clinician programmer system and method for calculating volumes of activation for monopolar and bipolar electrode configurations - A system and method for providing a volume of activation (VOA) of a stimulation electrode leadwire may include a processor that calculates a VOA for each of a plurality of sets of parameter settings of the leadwire, stores in a database each of the calculated VOAs in association with the respective set of parameter settings for which it was calculated, performs a curve fitting on threshold values determined for a plurality of waveforms to obtain an equation, obtains a set of parameter settings of the leadwire for a stimulation, and determines a VOA for the obtained set of parameter settings based on the stored VOAs, for example, using the equation. | 02-25-2010 |
20110313268 | Clinician programmer system and method for steering volumes of activation - A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set. | 12-22-2011 |
20110313487 | Clinician programmer system and method for steering volumes of activation - A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set. | 12-22-2011 |
20120014580 | PROGRAMMING INTERFACE FOR SPINAL CORD NEUROMODULATION - A tool for assisting in the planning or performing of electrical neuromodulation of a patient's spinal cord. The tool may have various functions and capabilities, including calculating a volume of activation, registering an electrode(s) shown in a radiologic image, constructing functional images of the patient's spinal anatomy, targeting of neuromodulation, finding a functional midline between multiple electrodes, determining the three-dimensional position of multiple electrodes, and/or accommodating for electrode migration. In certain embodiments, the tool can be embodied as computer software or a computer system. | 01-19-2012 |
20120212380 | PLANAR ANTENNA DEVICE AND STRUCTURE - The invention may provide an antenna device including a communication interface to couple the antenna device to an external device and a package housing with an adhesive surface. A planar antenna pattern may be fabricated on a substrate within the package housing, wherein the antenna pattern is configured to transmit an ultra-wideband signal and to receive a reflection of the transmitted signal. | 08-23-2012 |
20120265267 | CLINICIAN PROGRAMMER SYSTEM AND METHOD FOR CALCULATING VOLUMES OF ACTIVATION - A system and method for providing a volume of activation (VOA) of a stimulation electrode leadwire may include a processor that calculates a VOA for each of a plurality of sets of parameter settings of the leadwire, stores in a database each of the calculated VOAs in association with the respective set of parameter settings for which it was calculated, obtains a set of parameter settings of the leadwire for a stimulation, and determines a VOA for the obtained set of parameter settings based on the stored VOAs. | 10-18-2012 |
20120265268 | PROGRAMMING INTERFACE FOR SPINAL CORD NEUROMODULATION - A tool for assisting in the planning or performing of electrical neuromodulation of a patient's spinal cord. The tool may have various functions and capabilities, including calculating a volume of activation, registering an electrode(s) shown in a radiologic image, constructing functional images of the patient's spinal anatomy, targeting of neuromodulation, finding a functional midline between multiple electrodes, determining the three-dimensional position of multiple electrodes, and/or accommodating for electrode migration. In certain embodiments, the tool can be embodied as computer software or a computer system. | 10-18-2012 |
20120271376 | CLINICIAN PROGRAMMER SYSTEM AND METHOD FOR STEERING VOLUMES OF ACTIVATION - A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set. | 10-25-2012 |
20120314919 | SYSTEM AND METHOD FOR LEADWIRE LOCATION - A system and method for leadwire location may provide for recognition of the leadwire via analysis of a series of two-dimensional images that include representations of the leadwire, and/or determining an orientation of the leadwire with reference to a marker on the leadwire. | 12-13-2012 |
20120314924 | SYSTEM AND METHOD FOR ATLAS REGISTRATION - A system and method for associating anatomically significant regions with regions of one or more images may include automatically modifying images of different modalities according to different correction algorithms, providing a user interface for identifying a plane within three-dimensional data, scaling atlas structures to fit an anatomical image according to identified landmarks, registering an atlas to such an image via a combination of registration algorithms, and/or registering an atlas to such an image using a feature extraction algorithm. | 12-13-2012 |
20120330374 | SYSTEM AND METHOD FOR DETERMINING TARGET STIMULATION VOLUMES - A system and method may include determining a target stimulation volume based on modifying a patient population image for which an efficacious volume had been determined. A system and method for suggesting stimulation devices may include determining which stimulation device is capable of producing an output volume of activation that most closely matches the target volume. A system and method for facilitating selection of stimulation parameters may include graphically identifying a maximum volume in which tissue is stimulatable by an implanted stimulation device. A system and method may pre-compute volumes of activation that result from a predetermined modification of programming settings. A system and method may transmit stimulation programming settings from a stimulation programming module to a stimulation generating device. | 12-27-2012 |
20130039550 | SYSTEM AND METHOD FOR WEIGHTED ATLAS GENERATION - A system and method for generating a patient-specific anatomical atlas, e.g., includes, for each patient of a patient population: obtaining a respective anatomical atlas, and registering, by a computer processor, the respective anatomical atlas to an anatomical image of a current patient to obtain a respective registered anatomical atlas, and further includes, determining, by the processor, an average of the registered anatomical atlases. | 02-14-2013 |
20130116744 | VOA generation system and method using a fiber specific analysis - A system and method for generating an estimated volume of activation (VOA) corresponding to settings applied to a stimulation leadwire includes a processor performing the following: determining, for each of a plurality of neural elements, one or more respective parameters characterizing an electrical distribution along the neural element, looking up the one or more parameters for each of the neural elements in a look-up table (LUT), obtaining threshold values for each of the neural elements recorded in the LUT in association with the looked-up parameters, comparing, for each of the neural elements, a value of the leadwire settings to each of the respective threshold value, estimating based on the comparisons which of the neural elements would be activated by the settings, and generating a structure corresponding to a region including the neural elements estimated to be activated. | 05-09-2013 |
20130150711 | NON-INVASIVE MEDICAL CONDITION MONITORING APPARATUS - Embodiments of the present invention may provide a detector device including a communication interface to couple the detection device to an external antenna device. The detector device may detect medical condition(s) by performing a reference scan and a subsequent target scan. The target scan may be compared to the reference scan, and deviations from the reference scan may indicate the presence of the medical condition(s). According to embodiments of the present invention, the detection device may continuously monitor for medical condition(s) by performing an initial reference scan and subsequent target scans. Each target scan may be compared to the reference scan, and deviations from the reference scan may indicate the presence of the medical condition(s) or a change in the medical condition(s). | 06-13-2013 |
20130226261 | CLINICIAN PROGRAMMER SYSTEM AND METHOD FOR GENERATING INTERFACE MODELS AND DISPLAYS OF VOLUMES OF ACTIVATION - A system and method for displaying a volume of activation (VOA) may include a processor that displays via a display device a model of a portion of a patient anatomy that includes anatomical structures, displays via the display device and overlying the display of the model a VOA associated by the processor with a set of anatomical stimulation parameter settings, the display of the VOA, and graphically identifies interactions between the displayed VOA and a first subset of the anatomical structures associated with one or more stimulation benefits and a second subset of the anatomical structures associated with one or more stimulation side effects, where the graphical identifications differ depending on whether the interaction is with the first subset or the second subset. | 08-29-2013 |
20150066111 | PROGRAMMING INTERFACE FOR SPINAL CORD NEUROMODULATION - A tool for assisting in the planning or performing of electrical neuromodulation of a patient's spinal cord. The tool may have various functions and capabilities, including calculating a volume of activation, registering an electrode(s) shown in a radiologic image, constructing functional images of the patient's spinal anatomy, targeting of neuromodulation, finding a functional midline between multiple electrodes, determining the three-dimensional position of multiple electrodes, and/or accommodating for electrode migration. In certain embodiments, the tool can be embodied as computer software or a computer system. | 03-05-2015 |
20150088223 | VOA GENERATION SYSTEM AND METHOD USING A FIBER SPECIFIC ANALYSIS - A system and method for generating an estimated volume of activation (VOA) corresponding to settings applied to a stimulation leadwire includes a processor performing the following: determining, for each of a plurality of neural elements, one or more respective parameters characterizing an electrical distribution along the neural element, looking up the one or more parameters for each of the neural elements in a look-up table (LUT), obtaining threshold values for each of the neural elements recorded in the LUT in association with the looked-up parameters, comparing, for each of the neural elements, a value of the leadwire settings to each of the respective threshold value, estimating based on the comparisons which of the neural elements would be activated by the settings, and generating a structure corresponding to a region including the neural elements estimated to be activated. | 03-26-2015 |
20150297893 | CLINICIAN PROGRAMMER SYSTEM AND METHOD FOR STEERING VOLUMES OF ACTIVATION - A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set. | 10-22-2015 |
20160001080 | SYSTEM AND METHOD FOR DETERMINING TARGET STIMULATION VOLUMES - A system and method may include determining a target stimulation volume based on modifying a patient population image for which an efficacious volume had been determined. A system and method for suggesting stimulation devices may include determining which stimulation device is capable of producing an output volume of activation that most closely matches the target volume. A system and method for facilitating selection of stimulation parameters may include graphically identifying a maximum volume in which tissue is stimulatable by an implanted stimulation device. A system and method may pre-compute volumes of activation that result from a predetermined modification of programming settings. A system and method may transmit stimulation programming settings from a stimulation programming module to a stimulation generating device. | 01-07-2016 |
David Frederique Blum US
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20120069895 | High Quality Video Encoder - A computerized method for encoding and decoding video comprising: dividing a video frame into macro-blocks; Re-size the video frame into a lower resolution (“resized frame”). | 03-22-2012 |
David L. Blum, Athens, GA US
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20130289246 | INFLUENZA VIRUS ANTIBODIES AND IMMUNOGENS AND USES THEREFOR - The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of influenza virus infections. In particular, these antibodies may neutralize or limit the replication of influenza virus. Also disclosed are improved methods for producing such monoclonal antibodies, including novel immunogens for use in vaccination and production of protective immune responses. | 10-31-2013 |
Dennis Blum, East Brunswick, NJ US
Gary J. Blum, Walnut, IA US
Patent application number | Description | Published |
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20080245441 | PORTABLE WORKBENCH - A portable workbench is provided for holding a work piece, and includes a bench top, foldable legs, and a plurality of horizontal and vertical holes adapted to receive a pipe clamp for clamping the work piece to the bench top. The bench top is a torsion box with an internal grid so that the workbench is lightweight, yet strong and stable. The legs include two-piece crossbraces which are quickly and easily connected and disconnected via male and female ends and a securing pin. | 10-09-2008 |
Gina Lynn Blum, Cincinnati, OH US
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20150118168 | LATE STAGE ADDITION OF RHEOLOGY MODIFIER - Methods of making personal care compositions, such as dentifrices, involving the addition of rheology modifiers at a later stage in the personal care composition formation process. | 04-30-2015 |
20150118271 | PROCESS FOR MAKING A PERSONAL CARE COMPOSITION USING COMPACTED RHEOLOGY MODIFIERS - A method of making a personal care composition, such as dentifrice, using compacted rheology modifiers to control viscosity development. | 04-30-2015 |
Greg Blum, Charlotte, NC US
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20100039884 | FUEL MIXING SYSTEM - A process for mixing separate fluid streams is provided. The process includes the steps of providing a first fluid stream and a second fluid stream having an adjustable flow rate and together forming an output stream, monitoring at least one predetermined characteristic of the output stream, and adjusting the flow rate of the second fluid stream according to a predetermined algorithm. The predetermined algorithm is dependent upon the at least one of the predetermined characteristics of the output stream. | 02-18-2010 |
Gregory A. Blum, Cedar Rapids, IA US
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20160056778 | CASCODE POWER AMPLIFIER WITH VOLTAGE LIMITER - Cascode power amplifier with voltage limiter. A power amplification system can include an input transistor having an input transistor gate configured to receive a radio-frequency (RF) signal, an input transistor source coupled to a ground voltage, and an input transistor drain. The power amplification can further include an output transistor having an output transistor drain configured to output an amplified version of the RF signal, an output transistor gate coupled to a bias voltage, and an output transistor source. The power amplification system can further include a high voltage limiter coupled between the output transistor drain and output transistor gate. The high voltage limiter can be configured to prevent a gate-drain voltage of the output transistor from exceeding a high voltage threshold. | 02-25-2016 |
James M. Blum, Ann Arbor, MI US
Patent application number | Description | Published |
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20110087117 | REAL-TIME VISUAL ALERT DISPLAY - An alert system for patient treatment that incorporates patient data to display information in readily identifiable icons for vital organs, and in a useable, real-time, updated fashion that extracts data from the medical history, the current medical management, and the current physiologic monitors to produce warnings and alerts to enable practitioners to be made aware of physiologic systems at risk, (physiologic systems in normal range, borderline normal range, and abnormal range of function). These data are not only presented, but also use real-time queries and calculations to enable practitioners to have the types of data that would traditionally assist them in patient care but only be available by reviewing the medical literature and/or doing retrospective individual calculations while providing patient care. | 04-14-2011 |
20150031966 | EVALUTATING CARDIOVASCULAR HEALTH USING INTRAVASCULAR VOLUME - Non-invasive monitoring of cardiovascular health is performed by monitoring changes in the volume of blood in the venous side of the vascular system. The blood volume changes are determined from measurements of bioimpedance of limbs or neck, in particular changes in bioimpedance in response to blood modulating events performed on the limbs or neck, where bioimpedance is measured and compared before and after such events. | 01-29-2015 |
Jeffrey N. Blum, Pullman, WA US
Patent application number | Description | Published |
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20100010700 | MAPPING IN MOBILE DATA COLLECTION SYSTEMS, SUCH AS FOR UTILITY METER READING AND RELATED APPLICATIONS - A mobile data collection system may perform or facilitate monitoring and management of mobile automatic meter reading (MAMR) activities via out of route meter read identification and graphical route playback. In identifying out of route endpoints, the mobile data collection system receives an indication of each of the endpoints included in a predetermined meter reading route. The mobile data collection system executes the route detecting endpoints and collecting location information relating to out of route endpoints that are not included in the predetermined route. Location information identifying the out of route endpoints is then presented to a user. In facilitating graphical route playback, the mobile data collection system collects information as it progresses through the route. The collected information may then be used in a graphical playback of the route, which shows the mobile data collection system dynamically traveling through the route (e.g., on a map) and reading endpoints. | 01-14-2010 |
John Blum, Somerset, NJ US
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20110157343 | METHOD AND APPARATUS FOR SECURING PLANAR ORIENTATION OF ANALYSIS CHAMBER - An apparatus and method for imaging a biologic fluid sample quiescently residing within a chamber is provided. The chamber includes a first panel and a second panel, between which the biologic fluid sample quiescently resides. At least one of the first and second panels is flexible. The chamber has one or more fields that are each defined by a cross-sectional area. The apparatus comprises a field illuminator, a chamber flattener, a positioner, and an image dissector. The field illuminator has an objective lens. The chamber flattener has a platen with a window and a cover plate. The chamber flattener is operable to cause the chamber to assume a substantially uniform Z-axis position for substantially all of the fields within the chamber. The positioner is adapted to position the objective lens and the chamber relative to one another. The image dissector is adapted to image the sample residing within the chamber. | 06-30-2011 |
20110206557 | BIOLOGIC FLUID ANALYSIS CARTRIDGE - A biological fluid sample analysis cartridge is provided. The cartridge includes a housing, a fluid module, and an analysis chamber. The fluid module includes a sample acquisition port and an initial channel, and is connected to the housing. The initial channel is sized to draw fluid sample by capillary force, and is in fluid communication with the acquisition port. The initial channel is fixedly positioned relative to the acquisition port such that at least a portion of a fluid sample disposed within the acquisition port will draw into the initial channel. The analysis chamber is connected to the housing, and is in fluid communication with the initial channel. | 08-25-2011 |
John Blum, Petersham, MA US
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20140014169 | NANOSTRING MATS, MULTI-JUNCTION DEVICES, AND METHODS FOR MAKING SAME - Semiconductor nanostrings, mats containing semiconductor nanostrings, and devices and modules, such as, solar energy generating modules, including semiconductor nanostrings or mats containing semiconductor nanostrings are described herein. Methods for making multi-layer nanostrings and mats and other devices including multi-layer nanostrings are also described. | 01-16-2014 |
John Blum, Toms River, NJ US
Patent application number | Description | Published |
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20100174253 | Ostomy Appliance - A stoma adapter is described that is especially suited to a recessed stoma or a flush stoma. The stoma adapter effectively extends the discharge passage from the stoma, protects peristomal skin, and forms a bridge at the interface between the stoma and an ostomy appliance. The stoma adapter contains a substantially unobstructed discharge passage, at least for effluent flowing in a discharge direction. The stoma adapter includes a seal for sealing against the bowel wall. The stoma adapter has collapsing, expanding, flexible and reinforced designs. | 07-08-2010 |
20100211033 | TAP FOR A DRAINAGE BAG - A urine drainage bag, such as a urostomy bag, includes a drainage tap. The tap includes a tap member mounted to a housing so as to be pivotably movable between a closed, stowed position and an open, deployed position. In the closed position, the tap member is accommodated substantially within a chamber of the housing. The housing is disposed between front and rear walls of the bag, such that the tap is integrated into the seam of the bag. The tap further comprises a drip cap that is captively mounted on the tap member. A portion of the drip cap acts as a handle for pulling on the tap member. A portion of the drip cap also acts as a retainer or lock for blocking accidental closing of the tap member when attached to a night drainage apparatus. | 08-19-2010 |
20120179124 | CONTROLLED DISCHARGE OSTOMY APPLIANCE AND SHIELD THEREFOR - A controlled discharge ostomy appliance assembly comprises (i) a stoma seal that is self-urging with a dynamic damping characteristic that resists changes of seal volume, (ii) a press-fit coupling member displaceable from an unlocked position to a locked position as part of a press-fit process, and (iii) a single-use frangible portion. The assembly further includes a protector shield removably fastened to the appliance forming a combined assembly therewith. The protector shield comprises (i) a seal displacer manipulable for displacing the stoma seal to a non-operative position ready for fitting, (ii) a substantially rigid coupling member guard portion for protecting the state of the coupling member, and (iii) a bracing portion for bracing the single-use frangible portion. | 07-12-2012 |
20140364823 | CONTROLLED DISCHARGE OSTOMY APPLIANCE AND SHIELD THEREFOR - A controlled discharge ostomy appliance assembly comprises (i) a stoma seal that is self-urging with a dynamic damping characteristic that resists changes of seal volume, (ii) a press-fit coupling member displaceable from an unlocked position to a locked position as part of a press-fit process, and (iii) a single-use frangible portion. The assembly further includes a protector shield removably fastened to the appliance forming a combined assembly therewith. The protector shield comprises (i) a seal displacer manipulable for displacing the stoma seal to a non-operative position ready for fitting, (ii) a substantially rigid coupling member guard portion for protecting the state of the coupling member, and (iii) a bracing portion for bracing the single-use frangible portion. | 12-11-2014 |
Juliana Blum, Raleigh, NC US
Patent application number | Description | Published |
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20090028817 | Compositions and methods for soft tissue augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-29-2009 |
20110020271 | ELASTIN FOR SOFT TISSUE AUGMENTATION - The present invention provides compositions comprising isolated elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-27-2011 |
20120230950 | Compositions and Methods for Soft Tissue Augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 09-13-2012 |
20140356323 | Compositions and Methods for Soft Tissue Augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 12-04-2014 |
Juliana Blum, Wake Forest, NC US
Patent application number | Description | Published |
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20120028234 | TISSUE AND ORGAN GRAFT BIOREACTOR AND METHOD OF OPERATION - A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions. | 02-02-2012 |
20130345824 | TISSUED-ENGINEERED CONSTRUCTS - The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs. | 12-26-2013 |
Juliana L. Blum, Wake Forest, NC US
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20130013083 | Tissue-Engineered Constructs - Constructs including a tubular biodegradable polyglycolic acid scaffold may be coated with extracellular matrix proteins and are substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, an arterial graft, a venous graft, a duct graft, a skin graft, or a urinary graft or conduit. | 01-10-2013 |
Kenneth Blum, Austin, TX US
Patent application number | Description | Published |
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20160032391 | METHOD OF ESTABLISHING A GENETIC RISK STRATIFICASTION FOR GENETIC ADDICTION RISK ANALYSIS - Methods and kits for assessing severity index for alcohol abuse, drug abuse, and other reward deficiency syndromes. It has been discovered that a multifaceted non-specific RDS behaviors should be considered as the true “reward” phenotype (endophenotype) instead of a single subset RDS behavior such as alcoholism. In an embodiment of the present invention, it has been discovered that there are at least eleven risk alleles associated with ten candidate genes. The methods and kits of the present invention satisfy the need to classify patients at genetic risk for drug/alcohol seeking behavior prior to or upon entry to residential and or non-residential chemical dependency and pain programs. | 02-04-2016 |
Kevin Blum, West Lafayette, IN US
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20150257763 | OCCLUSION DEVICE - An occlusion device for placement within a body vessel may include a wire constructed support structure having a covering applied thereto. The covering includes a mixture of PET and ultra-high molecular weight polyethylene (UHMWPE). The covering is applied to the support structure via an electrospinning process to produce a non-woven fiber covering having increase strain capabilities relative to an electrospun PET covering without UHMWPE. The device has a nominal state that is radially expanded and a delivery state that is radially compressed and longitudinally extended for disposal within a low-profile delivery sheath. The covering increased strain capability allows for the device to have relative large diameter in the nominal state while still being capable of low-profile delivery. This occlusion device can provide faster occlusive capability when deployed and does not rely on delayed embolization. The covering extends across the vessel upon deployment to provide instant occlusion. | 09-17-2015 |
Kevin Blum, Lanesville, IN US
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20150105323 | COLLAGEN COMPOSITIONS AND METHODS OF USE - The present disclosure provides an engineered collagen composition comprising collagen, wherein the collagen composition is compressed to form a gradient of at least one physical property. Methods of using and of manufacturing the engineered collagen compositions of the present disclosure are also provided. | 04-16-2015 |
Kevin Matthew Blum, Lanesville, IN US
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20150119801 | STEERABLE INTRALUMINAL MEDICAL DEVICE - A steerable intraluminal medical device is described for use in navigating small diameter and curving arteries. The device includes a control handle that adjusts the direction of deflection of the tip throughout a 360° range of motion around the axis on the distal end. An optional locking mechanism is provided to maintain the desired angle of deflection during an intravascular procedure. | 04-30-2015 |
Kristen Blum, Whitehall, PA US
Patent application number | Description | Published |
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20140316302 | SAMPLE COLLECTION KIT - A sample collection kit includes a sample collector, a polycarbonate container, and a preservative solution. The sample collector includes an absorbent pad with a collecting element that receives a sample of oral fluid. The absorbent pad also includes an interior portion that extends into a handle. The handle includes an upper casing and a lower casing. The collecting element can be treated with a surfactant to optimize recovery of analytes from the oral sample and/or their absorbance onto the absorbent pad. A polycarbonate container receives the absorbent pad or the sample collector and stores it for testing of analytes. A dextran sulfate preservative solution is included in the polycarbonate container that inhibits enzymatic activity on a collected sample. | 10-23-2014 |
Kristen A. Blum, Whitehall, PA US
Patent application number | Description | Published |
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20090024060 | SAMPLE COLLECTOR - A collector includes a collecting element that receives a sample of bodily fluid. The collecting element may be an absorbent pad that has been treated with a surfactant to optimize recovery of analytes from the sample and/or their absorbance onto the absorbent material. An extractor is operably connected to a container and receives the collector to provide fluid communication between the collector and the container. The collector, when received by the extractor, is operable to release a volume of the sample into the container. | 01-22-2009 |
Kurt E. Blum, Murfreesboro, TN US
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20150308113 | BLOCK AND FOAM WALL SYSTEM - A wall system having high vertical and lateral stability as well as vertical loading capacity is disclosed. The wall system includes blocks formed from two opposing plates. The plates have a spacer holding the plates at a predetermined distance from one another. Each plate includes tongues and grooves for fitting together with adjacent blocks in the wall system when the blocks are stacked with one another. Once the blocks are stacked, the space between the opposing plates of the blocks is filled with an spray insulation to lock the blocks in place. | 10-29-2015 |
Manuel Blum, Pittsburgh, PA US
Patent application number | Description | Published |
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20100031330 | METHODS AND APPARATUSES FOR CONTROLLING ACCESS TO COMPUTER SYSTEMS AND FOR ANNOTATING MEDIA FILES - Methods and apparatuses for controlling access to computer systems and for annotating media files. One embodiment includes a method including generating a challenge to a user, wherein the challenge includes a verify part and a read part. The methods also includes prompting the user to solve both the verify part of the challenge and the read part of the challenge; receiving input from the user; determining if the input from the user relative to the verify part of the challenge corresponds with the known answer for the verify part of the challenge; and identifying the input from the user relative to the read part of the challenge as an answer to the read part of the challenge, if the input from the user relative to the verify part of the challenge corresponds with the known answer for the verify part of the challenge. | 02-04-2010 |
20140181960 | METHODS AND APPARATUSES FOR CONTROLLING ACCESS TO COMPUTER SYSTEMS AND FOR ANNOTATING MEDIA FILES - Methods and apparatuses for controlling access to computer systems and for annotating media files. One embodiment includes a method including generating a challenge to a user, wherein the challenge includes a verify part and a read part. The methods also includes prompting the user to solve both the verify part of the challenge and the read part of the challenge; receiving input from the user; determining if the input from the user relative to the verify part of the challenge corresponds with the known answer for the verify part of the challenge; and identifying the input from the user relative to the read part of the challenge as an answer to the read part of the challenge, if the input from the user relative to the verify part of the challenge corresponds with the known answer for the verify part of the challenge. | 06-26-2014 |
Matthew Blum, Chicago, IL US
Patent application number | Description | Published |
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20100269359 | DUAL WHEEL PIZZA CUTTER - A pizza cutter has a body portion, a front cutting wheel rotatably coupled to the body portion, and a rear cutting wheel rotatably coupled to the body portion. The front cutting wheel and the rear cutting wheel are aligned in a cutting direction. A top of the body portion opposite the front cutting wheel and the rear cutting wheel has a graspable handle. Adjacent to the handle and positioned generally over the front cutting wheel and/or the rear cutting wheel the body portion is provided with an upswept corner. The body portion also provides a front cutting wheel well and a rear cutting wheel well with the front cutting wheel well covering a portion of one side of the front cutting wheel, the rear cutting wheel well covering a portion of one side of the rear cutting, and the opposite sides of the front cutting wheel and the rear cutting wheel remain exposed. | 10-28-2010 |
Michael Blum, Western Springs, IL US
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20160027110 | DYNAMIC TICK TRADING PLATFORM - A trading platform comprising a processor and tangible computer readable storage media. The platform may comprise instructions for receiving and processing orders and bids. The platform may store the bids and offers in a bid and offer order book. The platform may group the bids and offers based on price and notional value. The platform may redistribute groupings of bids and offers after a new bid or offer is received in the platform. | 01-28-2016 |
Michael Blum, Phoenix, AZ US
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20130097261 | SAFE AND MONITORED VIRTUAL WORLD - The present invention relates to a system and method for safe electronic communication for children. According to one exemplary embodiment, the present invention provides a virtual world with avatars and online social interaction for children that is monitored by a parent or other guardian. In one embodiment, children may complete certain tasks for points that can be redeemed for certain awards. These tasks may include caring for a virtual pet that would allow the child to earn points to adopt a real pet from a pet store or humane society. | 04-18-2013 |
20130104246 | E-MAIL, TEXT, AND MESSAGE MONITORING SYSTEM AND METHOD - The present invention relates to a system and method for safe electronic communication for children. According to one exemplary embodiment, the present invention provides a method of monitoring e-mails, text messages, and other forms of electronic communication. In one embodiment, a software system monitors electronic messages for inappropriate content such as inappropriate words and excess skin flesh that would indicate that sexually explicit images are present in the message. If inappropriate content is detected, the message is first sent to a third party, usually a parent or guardian, for review and if acceptable to the third party, the message can be sent to the child. In another exemplary embodiment, the system and method of the present invention provides a calendaring system and points redemption system wherein points can be earned by children and redeemed for awards or merchandise. | 04-25-2013 |
Michael F. Blum, Birmingham, AL US
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20090306784 | Total Knee Prosthesis and Method for Total Knee Arthroplasty - A prosthetic knee implant for implantation into a mammal, which accommodates an anterior cruciate ligament substitute to provide stability to the knee implant. The prosthetic knee implant includes a femoral component having a pair of condylar surfaces and a tibial component having a surface portion adapted to slidably engage the femoral component upon rotation of the same. The femoral component further includes a central femoral recess between the condyles providing access to the femur for drilling a channel through which a cruciate ligament substitute may be integrated into the femur. The tibial component further includes a center portion defining an aperture through which the ligament substitute maybe threaded through the tibia and integrated therein, or anchored upon its surface. Also disclosed is a method used to replace the total knee joint in a mammal with the improved prosthetic knee implant of the present invention. | 12-10-2009 |
Michael F. Blum, Vestavia, AL US
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20090306783 | Total Knee Prosthesis and Method for Total Knee Arthroplasty - A prosthetic knee implant for implantation into a mammal, which accommodates an anterior cruciate ligament substitute to provide stability to the knee implant. The prosthetic knee implant includes a femoral component having a pair of condylar surfaces and a tibial component having a surface portion adapted to slidably engage the femoral component upon rotation of the same. The femoral component further includes a recess between the condyles defining an aperture through the femoral component. The tibial component further includes a center portion defining an aperture through the tibial component substantially at its center. The femoral aperture and the tibial aperture are adapted to receive an anterior cruciate ligament substitute for biasing the mammalian femur and tibia together. Also disclosed is a method used to replace the total knee joint in a mammal with the improved prosthetic knee implant of the present invention. | 12-10-2009 |
Michael Leroy Blum, Western Springs, IL US
Patent application number | Description | Published |
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20150073968 | FLOWBOOK ALTERNATIVE TRADING SYSTEM - An alternative trading system or platform for allowing a liquidity remover to place an order for the purchase or sale of a security or other commodity to be fulfilled by one or more liquidity providers. The platform may contain a rating module to allow members to create ratings of one another based on their own criteria; an indexor which utilizes the ratings to generate a list of liquidity providers offering a security of interest to a liquidity remover; a provider selector for determining which provider or providers to join in a transaction with the remover; and a price calculator for determining an execution price for the current transaction between a remover and a provider based on ratings and payment/price improvement configurations. | 03-12-2015 |
Paul Blum, Highlands Ranch, CO US
Patent application number | Description | Published |
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20090268622 | Route Tracing Program Configured to Detect Particular Network Element Making Type of Service Modification - One or more network elements that modify type of service values in a network are detected by sending route tracing messages having increasing time-to-live values and a designated type of service value from a first network element to a second network element. Type of service values are monitored in respective time exceeded messages received from respective network elements on a given network path between the first network element and the second network element responsive to the route tracing messages. At least a particular one of the network elements on the given network path that has made a modification in type of service value relative to the designated type of service value is identified, based on the monitored type of service values in the respective time exceeded messages. | 10-29-2009 |
20100118700 | Automatic Detection and Re-Configuration of Priority Status In Telecommunications Networks - A technique for ensuring that a node that carries high-priority protocol data units and low-priority protocol data units is properly configured to accord the high-level protocol data units priority treatment is described. In accordance with the illustrative embodiment, two streams of protocol data units are transmitted through a node to be tested. One stream comprises high-priority protocol data units, and the second stream comprises low-priority protocol data units. The processing capabilities of the node are then burdened by increasing the frequency of protocol data units transmitted to it, so that the node is compelled to treat the two streams differently, if, in fact, it is properly configured to treat them differently. If the node treats the two streams differently and accords the high-priority stream higher priority, then the node is properly configured. Otherwise, the node is re-configured to accord the high-priority stream higher priority. | 05-13-2010 |
Randall B. Blum, Peoria, IL US
Patent application number | Description | Published |
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20090287382 | Vehicle control system and method - A vehicle control system includes a first powertrain, a second powertrain, and a third powertrain. The first powertrain includes a first power source. The second powertrain includes a second power source. The third powertrain includes a third power source. The vehicle control system also includes an operator control interface. The operator control interface includes a first portion configured to receive a first operator input and a second portion configured to receive a second operator input. The first operator input and the second operator input are indicative of a desired speed and a desired direction. The vehicle control system additionally includes a controller configured to deliver a power control signal to at least one of the first powertrain, the second powertrain, and the third powertrain. The power control signal is a function of the first operator input and the second operator input. | 11-19-2009 |
Richard A. Blum, Atlanta, GA US
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20140107981 | CIRCUITS AND METHODS FOR ARTIFACT ELIMINATION - Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants. | 04-17-2014 |
Richard F. Blum, Bolingbrook, IL US
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20100135720 | DUCT FASTSEAM - A seam for ductwork has a male end portion integrally formed at a distal end of a duct wall and a female end portion integrally formed at another distal end of the duct wall. The female end portion includes a first fold and a second fold, which define a female groove for accommodating the male portion. A distal end of the second fold is bent transverse to the female groove prior to the male portion being inserted into the female groove. | 06-03-2010 |
Ron Blum, Roanoke, VA US
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20150219899 | Augmented Reality Eyewear and Methods for Using Same - A system for displaying a virtual image in a field of vision of a user comprising a lens; a source for emitting a light beam; and a reflector configured to manipulate and direct the light beam to display the image as a virtual image. A method comprising placing a lens having a reflector in front of a user's eye; and projecting, onto the reflector, a light beam associated with an image; manipulating the light beam such that it is focused at a location beyond the reflector and directing it towards the user's eye to display the image as a virtual image. A system comprising first and second lenses, reflectors, and light sources; corresponding pathways along which the light beams are directed from the corresponding source, into the corresponding lens, along a body portion of the corresponding lens, and to the corresponding reflector for display as a virtual image. | 08-06-2015 |
Ronald Blum, Roanoke, VA US
Patent application number | Description | Published |
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20080239236 | ENHANCED ELECTRO-ACTIVE LENS SYSTEM - A lens system and optical devices that provide enhanced vision correction are disclosed. The lens system includes an electro-active layer that provides correction of at least one higher order aberration. The higher order correction changes dynamically based on a user of the lens system's needs, such as a change by the user's gaze distance, pupil size, or changes in tear film following blinking, among others. Optical devices are also described that use these and other lens systems to provide correction of higher order aberrations. An optical guide is also described that guides the user's line of sight to see through a lens region having a correction for a higher order aberration. | 10-02-2008 |
20110090455 | Opthalmic Lens With Regressive and Non-Regressive Rotationally Symmetric Optical Design Elements - Aspects of the present invention provide an ophthalmic lens comprising at least one regressive and at least one non-regressive rotationally symmetric optical design element. The regressive and non-regressive optical design elements can be combined so as to form a desired optical power profile for the lens while simultaneously exploiting the different relative orientation of the astigmatic vectors of the constituent regressive and non-regressive design elements, thereby resulting in reduced unwanted astigmatism. The regressive and non-regressive rotationally symmetric optical design elements can be positioned on different lens surfaces and in optical communication or can be collapsed onto the same lens surface. The regressive and non-regressive rotationally symmetric optical design elements can each contribute to the total add power of an ophthalmic lens. The regressive and non-regressive rotationally symmetric optical design elements can be combined with any other optical design feature positioned on the same or a different surface of the lens. | 04-21-2011 |
20120212696 | VARIABLE OPTICAL ELEMENT COMPRISING A LIQUID CRYSTAL ALIGNMENT LAYER - In some embodiments, a first optical device may be provided. The first optical device may include a first substrate, a liquid crystal alignment layer comprising a controlled pattern of features each having a dimension of at most 2 microns, and a liquid crystal layer disposed adjacent to the alignment layer that includes liquid crystal molecules. | 08-23-2012 |
20120229754 | Electronic Lens Comprised of Hybrid Matertials - Embodiments described herein may provide an electro-active lens. The electro-active lens may comprise a first substrate, a second substrate, and an electro-active element disposed between the first substrate and the second substrate. The electro-active element may be configured to alter the optical power of at least a portion of the electro-active lens. The first substrate may comprise a different material than the second substrate. | 09-13-2012 |
20120300171 | Programmable Ophthalmic Lenses - Ophthalmic lenses are described including a deformable layer and a deformable membrane disposed opposite the deformable layer. The lens is configured with at least two regions of adjustable optical power, such as by using a patterned electrode which is used to drive the membrane move axially along an optical path of the lens. A surface of the deformable layer is configured to expand and/or contract based on movement of the membrane along the optical path of the lens, such as by bonding one side of the deformable layer to the membrane and bonding the other side to a fixed optical element layer. | 11-29-2012 |
20130027655 | Electro-Active Lenses Including Thin Glass Substrates - An electro-active optical cell is described including a layer of electro-active material, a front glass substrate member, and a back glass substrate member. The optical cell is capable of independently providing changeable optical power with the application of an electrical potential. The cell is also configured to be affixed to an external surface of a plastic substrate and to provide the changeable optical power, with at least one of the front substrate or the back substrate of the optical cell being an outermost optical layer. The layer of electro-active material may have a thickness less than 10 μm, and the glass substrate members may each have a thickness approximately between 20 μm and 500 μm. | 01-31-2013 |
20130050639 | OBLIQUE-INCIDENCE DEPOSITED SILICON OXIDE LAYERS FOR DYNAMIC OPHTHALMIC LENSES - An ophthalmic lens including an electro-active optical element including a substrate; a liquid crystalline material; and at least one first layer. The at least one first layer can include a layer of silicon oxide (SiOx) disposed between the liquid crystalline material and the substrate, and deposited onto a surface of the substrate at an oblique angle in reference to a plane normal to the mean surface of the substrate facing the liquid crystalline material. | 02-28-2013 |
20130070198 | MOISTURE-RESISTANT ELECTRONIC SPECTACLE FRAMES - Eyewear including an optical functional member, control electronics, and a sealed electrical connective element connecting the electronics to the optical functional member. The connective element can directly connect the electronics to the optical functional member, or can connect through an intermediate contact, e.g., a plug-and-receptacle. The connective element can be routed from the electronics, around a rimlock of the eyewear to the optical functional member. The connective element can be a conductive compressible member, such as conductive rubber. In some embodiments, the connective element can be a multiconductor cable. | 03-21-2013 |
20130215374 | EYEWEAR DOCKING STATION AND ELECTRONIC MODULE - An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device. | 08-22-2013 |
20130235332 | EYEWEAR INCLUDING A DOCKING STATION - Eyewear is provided including a frame and an electronic docking station. The docking station may be configured to provide power to a docked electrical component, such as a camera, an audio player, a video player, etc. The electrical component docked into the docking station may provide a power source. The eyewear may also include an electro-active lens and/or a heads up display. | 09-12-2013 |
20130242253 | Eyeware Including A Heads Up Display - Eyewear is provided including a frame, a visor attached to frame and a heads up display. The heads up display may be housed in the visor. The visor may be configured to be positioned in multiple positions relative to the pupil of a wearer's eye, and/or adjustably positioned so that the heads up display may be transitioned between positions within the line of sight of the wearer and out of the line of sight of the wearer. The heads up display may be configured to be controlled by a remote controller, e.g. a wrist watch. The heads up display may be monocular or binocular. The eyewear may also include an electro-active lens. | 09-19-2013 |
20130242256 | METHOD AND APPARATUS FOR DETECTING ACCOMMODATION - A sensor system includes at least two sensors for distinguishing accommodative stimuli from changes in ambient lights levels and task-induced changes in the pupil diameter. When implanted, the first sensor is disposed completely within the pupil; even when fully constricted, the pupil does not occlude the first sensor, allowing the sensor to make precise measurements of ambient luminous flux levels. The pupil occludes part of the second sensor's active area(s) as the pupil dilates and constricts. As a result, the second sensor measures both ambient luminous flux and pupil diameter. A processor estimates the pupil diameter and determines whether it's changing in response to accommodative stimuli or other factors by comparing to predetermined values. The sensor system sends a signal to an optical component, which in turn can respond by changing optical power to focus for near vision upon detection of accommodative stimuli. | 09-19-2013 |
20130250135 | Eyewear Including A Remote Control Camera - Eyewear is provided including a frame, and a camera connected with the frame, in which the camera is configured to be controlled by a remote controller. The camera may be configured to capture video and/or a photo. The eyewear may include data storage, and the camera may be connected to the data storage. A wrist watch may be configured to act both as a time piece and a controller of the camera. The eyewear may also include a heads up display and/or a video file player. The eyewear may also include an electro-active lens. | 09-26-2013 |
20140043584 | Dynamic Ophthalmic Lens Capable of Correcting Night and Day Vision - Disclosed herein is a device that includes a host lens and a dynamic lens adapted to adjust its optical power based upon an input. The dynamic lens is in optical communication with the host lens. The device further comprises a photosensor, a controller electrically connected to the photosensor, and an actuator electrically connected to the controller. The actuator is also connected to the dynamic lens. The actuator provides an input interface to the dynamic lens, which is actuated based upon a signal received from the photosensor. The dynamic lens having a first zone of changeable optical power adapted to adjust its optical power within the range of −0.75 D to +0.75 D and an “optional” second zone of changeable optical power adapted to adjust its optical power within the range of +50 D to +1.25 D. | 02-13-2014 |
20140093661 | Selective Blue Light Filtered Optic - Disclosed herein is a method that comprises providing a solution containing a dye or a dye mixture, ultrasonicating the solution to reduce the average size of aggregates of the dye or dye mixture contained in the solution, and incorporating the dye or the dye mixture in the optical path of a device that transmits light. | 04-03-2014 |
20140160426 | Opthalmic Lens With Regressive And Non-Regressive Rotationally Symmetric Optical Design Elements - Aspects of the present invention provide an ophthalmic lens comprising at least one regressive and at least one non-regressive rotationally symmetric optical design element. The regressive and non-regressive optical design elements can be combined so as to form a desired optical power profile for the lens while simultaneously exploiting the different relative orientation of the astigmatic vectors of the constituent regressive and non-regressive design elements, thereby resulting in reduced unwanted astigmatism. The regressive and non-regressive rotationally symmetric optical design elements can be positioned on different lens surfaces and in optical communication or can be collapsed onto the same lens surface. The regressive and non-regressive rotationally symmetric optical design elements can each contribute to the total add power of an ophthalmic lens. The regressive and non-regressive rotationally symmetric optical design elements can be combined with any other optical design feature positioned on the same or a different surface of the lens. | 06-12-2014 |
20140204333 | ADJUSTABLE ELECTRO-ACTIVE OPTICAL SYSTEM AND USES THEREOF - The present invention relates generally to electro-active optical systems, such as a pair of spectacles having one or more lenses that employ electro-active optical structures. In some embodiments, the invention relates to electro-active optical systems whose position can be adjusted relative to a wearer's face. In some embodiments, the invention relates to methods of performing such adjustments. | 07-24-2014 |
20140327875 | ADVANCED ELECTRO-ACTIVE OPTIC DEVICE - Ophthalmic lenses are described including an ophthalmic base, and a plurality of electro-active elements, such as dynamic micro-lenses or micro-prismatic apertures. Each electro-active element may be configured to dynamically change optical power. The ophthalmic lens may be configured such that an optical power of the ophthalmic lens focuses mostly one image at one time on the retina of the eye of the wearer. The ophthalmic lens may be, for example, a spectacle lens, other types of specialty lenses such as used for gaming and the like, a contact lens, an intra-ocular lens, and intra-ocular optic, etc. Each electro-active element may include liquid crystal, such as dichroic, non-dichroic, nematic, and/or cholesteric liquid crystal. The electro-active elements may comprise non-dichroic liquid crystal, and gaps between the electro-active elements may include a dichroic liquid crystal, or the electro-active elements may be shaped and arranged in a substantially conformal pattern. | 11-06-2014 |
20150248026 | MOISTURE-RESISTANCE ELECTRONIC SPECTACLE FRAMES - Eyewear including an optical functional member, control electronics, and a sealed electrical connective element connecting the electronics to the optical functional member. The connective element can directly connect the electronics to the optical functional member, or can connect through an intermediate contact, e.g., a plug-and-receptacle. The connective element can be routed from the electronics, around a rimlock of the eyewear to the optical functional member. The connective element can be a conductive compressible member, such as conductive rubber. In some embodiments, the connective element can be a multiconductor cable. | 09-03-2015 |
20150250584 | ELECTRO-ACTIVE INTRAOCULAR LENSES - An intraocular lens system is presented that comprises an electro-active lens comprising multiple independently controllable zones or pixels, and a controller capable of being remotely programmed. | 09-10-2015 |
20150323812 | SELECTIVE WAVELENGTH FILTERING WITH REDUCED OVERALL LIGHT TRANSMISSION - A system is provided that selectively blocks blue light in addition to having low overall transmittance values. The average value of the transmission spectrum of the system across the wavelength range 400 nm-470 nm is between 0% and 30% and the average value of the transmission spectrum across the wavelength range 470 nm-700 nm is between 0% and 70%. The transmission spectrum of the system has a first local minimum in transmission between 400 nm-470 nm. | 11-12-2015 |
Ronald D. Blum, Rosnoke, VA US
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20090195749 | ELECTRO-OPTIC LENS WITH INTEGRATED COMPONENTS FOR VARYING REFRACTIVE PROPERTIES - A lens for dynamically correcting refractive error is disclosed, the lens system comprising: a lens having at least one electro-active element having a refractive property that is alterable, the lens being capable of being shaped to fit a housing without hindering performance of the electro-active element, a controller in communication with each of the at least one electro-active element thereto, and an input generator adapted for generating an input signal and transmitting the input signal to the controller, the input signal being generated based at least in part on an input parameter. | 08-06-2009 |
Ronald David Blum, Roanoke, VA US
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20130245754 | ADAPTIVE INTRAOCULAR LENS - An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device. | 09-19-2013 |
20130338767 | DEVICES AND METHODS FOR DYNAMIC FOCUSING MOVEMENT - An implantable ophthalmic device with one or more optical elements coupled to one or more shape-memory members provides dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia. Running current from a power supply through the shape-memory members causes the shape-memory members to heat up. Once the current heats the shape-memory members past a forward phase-transition temperature, the shape-memory members change shape, which, in turn, causes the optical element(s) to move, yielding a corresponding change in effective optical power. Cooling the shape-memory members (e.g., by reducing or stopping the flow of current) below a reverse phase-transition temperature causes the shape-memory members to return to their original shape, which, in turn, restoring the optical element(s) to their original positions and returning the effective optical power to its original level. | 12-19-2013 |
20150316688 | PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC - A system is provided comprising an optical filter. The optical filter comprises a Cu-porphyrin dye compound. The transmission spectrum of the system has an average transmission across the wavelength range of 460 nm-700 nm of at least 80%. The transmission spectrum of the system has an average transmission across the wavelength range 400 nm-460 nm that is less than 75%. | 11-05-2015 |
Saul C. Blum, Monroe, NJ US
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20140134743 | METHOD FOR IDENTIFYING LAYERS PROVIDING CORROSION PROTECTION IN CRUDE OIL FRACTIONS - A method for determining and identifying corrosion protective layers that provide corrosion protection against crude oils and crude oil fractions is disclosed. The method identifies naturally occurring constituents in crude oils that indirectly provide corrosion protection. A method assessing the potential of these constituents is also disclosed. The method includes exposing metal coupons with the crude oil or crude fraction of interest at the expected operating temperature of concern. The corrosion potential assessment further analyzes the exposed coupons with transmission electron microscopy and an additional high temperature exposure that challenges the tenacity of the protection offered by the corrosion protective layer. | 05-15-2014 |
Scott Blum, Beaverton, OR US
Patent application number | Description | Published |
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20120027209 | USING A TRUSTED-PLATFORM-BASED SHARED-SECRET DERIVATION AND WWAN INFRASTRUCTURE-BASED ENROLLMENT TO ESTABLISH A SECURE LOCAL CHANNEL - A system and method for establishing a connection on a mobile computing device includes generating a secret on a trusted platform of the mobile computing device. The secret is transported to a subscriber identity module (SIM)/Smartcard on the mobile computing device. A secure local communication channel is established between the trusted platform and the SIM/Smartcard using the secret. | 02-02-2012 |
Scott A. Blum, Jackson, WY US
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20140380164 | SYSTEMS AND METHODS FOR DISPLAYING WEBSITE CONTENT - A machine-executable method for displaying webpage media content comprises a network device receiving an input from a computing system. The network device verifies whether a user associated with the computing system is a logged-in member. If the user is a logged-in member, display or playback of the media content immediately begins on a display device or a webpage display application of the computing system, without receiving any further input from the computing system. | 12-25-2014 |
Scott Alan Blum, Jackson, WY US
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20090078776 | CARBON TRANSACTION CARD - A transaction card wherein at least a portion of the card is carbon. | 03-26-2009 |
20090291805 | EXERCISE APPARATUS AND METHODS - An exercise apparatus including a video display. In certain embodiments the apparatus includes an integrated platform. Memory within the apparatus contains a library of instructional exercise programs, such as yoga, Pilates, body toning and stretching routines. The apparatus may also connect to a network, such as the Internet to stream and/or download additional exercise programs. A user interface enables the user to select from available programs, which are shown on the video display. Audio for the programs may be provided via speakers or though headphones, which may be rechargeable and/or wireless. | 11-26-2009 |
20110201477 | EXERCISE APPARATUS AND METHODS - An exercise apparatus including a video display. In certain embodiments the apparatus includes an integrated platform. Memory within the apparatus contains a library of instructional exercise programs, such as yoga, Pilates, body toning and stretching routines. The apparatus may also connect to a network, such as the Internet to stream and/or download additional exercise programs. A user interface enables the user to select from available programs, which are shown on the video display. Audio for the programs may be provided via speakers or though headphones, which may be rechargeable and/or wireless. | 08-18-2011 |
20120237910 | EXERCISE APPARATUS AND METHODS - An exercise apparatus including a video display. In certain embodiments the apparatus includes an integrated platform. Memory within the apparatus contains a library of instructional exercise programs, such as yoga. Pilates, body toning and stretching routines. The apparatus may also connect to a network, such as the Internet to stream and/or download additional exercise programs. A user interface enables the user to select from available programs, which are shown on the video display. Audio for the programs may be provided via speakers or though headphones, which may be rechargeable and/or wireless. | 09-20-2012 |
20130320095 | TRANSACTION CARDS AND ASSOCIATED METHODS - A transaction card having a first layer and a second layer, wherein the first layer is metal and the second layer is carbon. | 12-05-2013 |
20140138443 | TRANSACTION CARD - A transaction card comprising a plurality of metal flakes suspended in a non-metallic matrix. | 05-22-2014 |
20140158773 | TRANSACTION CARDS AND ASSOCIATED METHODS - A transaction card having a first layer and a second layer, wherein the first layer is metal and the second layer is a polymer. | 06-12-2014 |
20140187384 | EXERCISE APPARATUS AND METHODS - An exercise apparatus including a video display. In certain embodiments the apparatus includes an integrated platform. Memory within the apparatus contains a library of instructional exercise programs, such as yoga, Pilates, body toning and stretching routines. The apparatus may also connect to a network, such as the Internet to stream and/or download additional exercise programs. A user interface enables the user to select from available programs, which are shown on the video display. Audio for the programs may be provided via speakers or though headphones, which may be rechargeable and/or wireless. | 07-03-2014 |
20150178616 | TRANSACTION CARDS AND ASSOCIATED METHODS - A transaction card having a first layer and a second layer, wherein the first layer is metal and the second layer is a polymer, polycarbonate, or carbon. The metal layer may be stainless steel plated with gold. | 06-25-2015 |
Tim Blum, Columbus, OH US
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20140103075 | PROCESS AND DEVICE FOR DELIVERY OF FLUID BY CHEMICAL REACTION - Processes and devices for delivering a fluid by chemical reaction are disclosed. A chemical reaction is initiated in a reaction chamber to produce a gas, and the gas acts upon a piston to deliver the fluid. Preferred devices typically include an upper chamber, a lower chamber, a fluid chamber, a piston between the lower chamber and the fluid chamber, and a barrier between the upper chamber and the lower chamber. When the barrier is broken, reagents in the upper chamber and the lower chamber are mixed together to generate the gas. | 04-17-2014 |
Timothy M. Blum, Columbus, OH US
Patent application number | Description | Published |
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20140296782 | INJECTION DEVICES WITH ERGONOMIC ENHANCEMENTS - Injection devices with ergonomic enhancements are disclosed. Generally, the injection devices include large oversized grips, including flanges at the base end of the device for enhanced stability. Push-type and squeeze-type devices are described, as well as manual injectors and auto-injectors. Such injection devices are useful for delivering a fluid (e.g. medication) to a patient. | 10-02-2014 |
20140324022 | PROCESSES FOR DELIVERY OF VISCOUS DRUG THERAPIES - Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein. | 10-30-2014 |
20150313677 | REMOTE MANIPULATOR DEVICE - A system for operating a catheter having a distal end adapted to be navigated in the body, and a proximal end having a handle with a translatable control and a rotatable control for acting on the distal end of the device includes a support for receiving and engaging the handle of the catheter; a translation mechanism for advancing and retracting the support to advance and retract a catheter whose handle is received in the support; a rotation mechanism for rotating the support to rotate a catheter whose handle is received in the support; a translation operator for engaging the translatable control of a catheter whose handle is received in the support and operating the translatable control to act on the distal end of the device; and a rotation operator for engaging the rotatable control of a catheter whose handle is received in the support and operating the rotatable control to act on the distal end of the device. | 11-05-2015 |
20150314070 | Chemical Engines and Methods for Their Use, Especially in the Injection of Highly Viscous Fluids - Chemical engines and processes for their use and construction are described. The chemical engines can provide powerful and compact devices, especially autoinjectors for the rapid, powered injection of viscous medicines. Novel formulations and designs of chemical engines and delivery technologies employing the chemical engines are described. | 11-05-2015 |