Ceragioli
Dennis M. Ceragioli, Pittsburg, CA US
Patent application number | Description | Published |
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20100030839 | NETWORK ARCHITECTURE FOR SECURE DATA COMMUNICATIONS - A network architecture includes a perimeter network connected between an internal network and an external network. The perimeter network includes one or more external edge nodes that are connected to the external network and a plurality of proxy servers that are each connected to one or more of the external edge nodes. One or more internal edge nodes are connected between the plurality of proxy servers and the internal network. The proxy servers are operable to establish a first secure connection between a destination through the external network and a second secure connection to a destination in the internal network. Each of the plurality of proxy servers provide a substantially identical identification for authentication when establishing the first and second secure connections. | 02-04-2010 |
Silvia Ceragioli, Ceriano Laghetto IT
Patent application number | Description | Published |
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20090306424 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS - The present invention refers to a process for preparing a compound of formula (I) | 12-10-2009 |
Silvia Ceragioli, Milano IT
Patent application number | Description | Published |
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20090118537 | Process for the Preparation of Contrast Agents - The present invention refers to a process for preparing a compound of formula (I) through a carboxymethylation reaction occurring in the presence of a suitable alkylating agent and of a base, without the need of monitoring the pH of the reaction environment. The compound of formula (I) is a useful intermediate in the preparation of diagnostic contrast agents for MRI techniques. | 05-07-2009 |
20110207960 | Process For The Preparation Of Iodinated Contrast Agent - The present invention relies on a process for the preparation of non ionic iodinated contrast agents and, in more details, it relates to a process for the preparation of Iopamidol in high yields and with a high degree of purity. In more details, the invention discloses a process for the preparation of a compound of formula (III) comprising the 5 condensation reaction a compound of formula (II) with 2-amino-1,3-propandiol, being said reaction carried out in an aprotic dipolar solvent and in the presence of an alkaline or alkaline rare earth metal oxide or hydroxide. | 08-25-2011 |
20120232151 | Process for the Preparation of Gadobenate Dimeglumine Complex in a Solid Form - The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions. | 09-13-2012 |
Silvia Ceragioli, Milan IT
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20150329464 | CONTINUOUS PROCESS FOR THE PREPARATION OF (S)-2-ACETYLOXYPROPIONIC ACID CHLORIDE - The present invention relates to a continuous method for the preparation of (S)-2-acetyloxypropionic acid from an aqueous solution of lactic acid and acetic anhydride, in acetic acid. (S)-2-acetyloxypropionic acid is used for the preparation of (S)-2-acetyloxypropionic acid chloride, an essential intermediate compound for the preparation of lopamidol and has to be industrially produced with high purity and suitable quality for producing lopamidol according to the Pharmacopoeia requirements. The continuous process according to the invention, comprises therefore also the chlorination steps of (S)-2-acetyloxypropionic acid with thionyl chloride to give the corresponding (S)-2-acetyloxypropionic acid chloride which is further distilled to give the suitable purity characteristics for its use for the preparation of non-ionic iodinated contrast agents as lopamidol. | 11-19-2015 |