Patent application number | Description | Published |
20080221562 | TISSUE TREATMENT SYSTEM AND METHOD FOR TISSUE PERFUSION USING FEEDBACK CONTROL - A system, ablation probe, and method is provided for treating tissue, e.g., tissue having tumors. The treatment system is configured to automatically deliver infusaid to tissue when needed and comprises an ablation probe having an ablative element and at least one perfusion exit port. The system further comprises an ablation source operably coupled to the ablative element, and a pump assembly operably coupled to the perfusion exit port(s). The pump assembly is configured for pumping infusaid out through the perfusion exit port(s), preferably during the ablation process. The system further comprises a feedback device configured for controlling the amount of infusaid displaced by the pump assembly based on a sensed tissue parameter, e.g., tissue temperature or tissue impedance. For example, the feedback device can comprise a sensor configured for sensing the tissue parameter, and a perfusion controller configured for controlling the pump assembly based on the sensed tissue parameter. As another example, the feedback device can comprise a perfusion valve associated with the distal end of the shaft. In this case, the perfusion valve forms the perfusion exit port, wherein the perfusion valve changes the size of the perfusion exit port based on tissue temperature. | 09-11-2008 |
20090069800 | SURFACE ELECTRODE MULTIPLE MODE OPERATION - A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted. | 03-12-2009 |
20100274241 | SURFACE ELECTRODE MULTIPLE MODE OPERATION - A surface electrode for ablating tissue is provided. The surface electrode comprises a base, a plurality of tissue penetrating needle electrodes extending from the surface of the base an adjustable distance, and an electrical interface coupled to the plurality of needle electrodes. The adjustability of the needle electrodes allows the depth that the needle electrodes penetrate through tissue to be adjusted. | 10-28-2010 |
Patent application number | Description | Published |
20090124376 | NETWORKED GAMING SYSTEM INCLUDING ANONYMOUS BIOMETRIC IDENTIFICATION - Networked gaming systems with anonymous player biometric identification and tracking, and associated methods, are disclosed. Also disclosed are a responsible gaming system and method, an anonymous player Bonusing method and system, a money laundering identification system and method, a distributed casino surveillance system and on electronic gaming machines, and a method and system for electronic re-configuration and/or download of a gaming machine based upon anonymous player identification using biometrics at the gaming device. | 05-14-2009 |
20090186701 | Networked Gaming System With Stored Value Cards and Method - Disclosed are gaming machines, gaming systems and methods including stored value cards. Networked gaming systems are described which include one or more gaming machines with a stored value card acceptor, casino and/or slot management systems with a stored value server for authenticating stored value cards, verifying stored value, and updating value associated with the stored value cards, and a kiosk system for issuing, validating, and accounting for value associated with updateable stored value cards. | 07-23-2009 |
20090239667 | Networked Gaming System Including A Location Monitor And Dispatcher Using Personal Data Keys - A networked gaming system is disclosed that includes location detection and dispatcher servers operative together with one or more wireless personal digital (PDK) devices communicating with receiver/decoders (RDCs) for tracking and communicating with casino employees and patrons throughout the casino. An employee and patron tracking system in a casino is disclosed wherein beverage and other service staff are properly assigned, dispatched to the right patron or location and can be located and tracked throughout various transactions. | 09-24-2009 |
20120108337 | GESTURE ENHANCED INPUT DEVICE - Various embodiments disclosed herein are directed to a virtual player interface such as button deck for a gaming device. The interface includes a touch screed display which displays one or more button icons. The size, shape and location of the button icons may be reconfigured based upon player interaction or selection. Button functions or selections may be combined into a single button. The button reconfiguration may be saved to a player account to be applied when the player uses the gaming device or other applicable device. Haptic or audible feedback may be applied to the button icon based upon the location of the player's touch relative to a target position on the icon. | 05-03-2012 |
20120166265 | NETWORKED GAMING SYSTEM WITH STORED VALUE CARDS AND METHOD - Disclosed are gaming machines, gaming systems and methods including stored value cards. Networked gaming systems are described which include one or more gaming machines with a stored value card acceptor, casino and/or slot management systems with a stored value server for authenticating stored value cards, verifying stored value, and updating value associated with the stored value cards, and a kiosk system for issuing, validating, and accounting for value associated with updateable stored value cards. | 06-28-2012 |
20120172119 | Gaming System, Method and Device for Generating Images Having a Parallax Effect Using Face Tracking - Gaming devices and methods are set forth which provide for face or body tracking to provide gesture input and also to generate content displayed based upon the motion parallax of the player to create a 3D effect. In a community gaming environment gaming content may be superimposed over real time or recorded scenes to create a 3D effect between players of the community game. | 07-05-2012 |
20120322544 | NETWORKED GAMING SYSTEM WITH STORED VALUE CARDS AND METHOD - Disclosed are gaming machines, gaming systems and methods including stored value cards. Networked gaming systems are described which include one or more gaming machines with a stored value card acceptor, casino and/or slot management systems with a stored value server for authenticating stored value cards, verifying stored value, and updating value associated with the stored value cards, and a kiosk system for issuing, validating, and accounting for value associated with updateable stored value cards. The stored value server may also be configured to accept and enforce issuance and redemption rules such as providing for discounted purchase and enhanced redemption. | 12-20-2012 |
20130080238 | Method and System for Operating a Customer or Player Loyalty System Including a Portable Device Such as a Smartcard - A method and system are set forth which include one or more terminals providing near field communication with an electronic device held by the user such as a smart card. The device includes a display panel configured to persistently display a visual condition associated with the user's account, promotional status or as selected by the user. | 03-28-2013 |
20130225270 | PLAYER GAMING CONSOLE, GAMING MACHINE, NETWORKED GAMING SYSTEM AND METHOD - Gaming devices, systems, software products and methods are disclosed that provide for the play of a bonus game upon a player achieving eligibility during play of a base game. Indicators such as scalars are displayed to graphically show progress toward eligibility. The bonus games may include a Bingo game or a playing-card based game like Poker. | 08-29-2013 |
20130231180 | NETWORKED GAMING SYSTEM INCLUDING ANONYMOUS PLAYER BIOMETRIC IDENTIFICATION AND TRACKING - A system and method are set forth which provides for biometric identification at a first server of an identified user and an established anonymous user and a device such as a gaming device and for using a second device such as a cellular telephone interfacing with the device to also access a second server which may also store biometric information as well as chargeable account information. If a user cannot be identified the first server establishes a new anonymous player account. Location determination may also be used where use of the device is subject to area use restrictions, such as remote gaming, to enable or disable the restricted use. | 09-05-2013 |
20130331184 | Gaming Device, Method and Virtual Button Panel for Selectively Enabling a Three-Dimensional Feature at a Gaming Device - Gaming devices and methods are set forth which provide for face, body and/or tracking to enable 3D rendering of images at a virtual button panel. Lenticular barrier or motion parallax technology may be used. A player's interface with the button panel may be through touch a touch screen or sensing of non-touch gestures. | 12-12-2013 |
20140094256 | Apparatus, System and Method for Presenting Different Wagering Games for Concurrent Play - Apparatus, methods and systems are set forth to enable a player to play several, different concurrent games at a gaming device. The player selects the games to play from a game library and a processor assigns the game instances to real estate at the gaming device display. The player may record wagers to play the games. A processor determines game cycle times and choreographs play of the games' start and stop cycles to provide an appealing and serial display of game outcomes to the player. | 04-03-2014 |
20140094279 | Apparatus, System and Method for Providing a Community Wagering Game at a Gaming Machine - A system, method and apparatus are set forth for providing a system-wide competitive game where players of gaming devices may wager upon the game. In an embodiment the game is a competitive racing game such as an auto race. Players wager upon a race competitor and those players wagering upon the winning contestant are issued an award. The system and method provides a mechanism for sharing the award among the winning players | 04-03-2014 |
Patent application number | Description | Published |
20100140090 | Gel suspension apparatus - A method and apparatus for expeditiously carrying out the preparation and imaging steps of the electrophoresis process. The apparatus of the invention includes a novel supporting surface comprising TEFLON® AF that acts as a multi-function gel supporting surface which minimizes the probability of damaging the gel during transfer and provides a supporting surface that has an index of refraction lower than that of water and that of water based gel. When the TEFLON® AF supporting surface is used to support the gel, or other mostly aqueous, fluorescent sample, the surface becomes a planar, aqueous core waveguide which traps the excitation light thereby increasing the efficiency of excitation. | 06-10-2010 |
20100140094 | Gel excitation apparatus - A gel excitation apparatus for exciting a gel that includes a container for holding an aqueous solution within which the gel can be positioned, at least one light source disposed proximate the container for irradiating the gel with radiation within at least a first wavelength band, the first wavelength band selected to excite the gel to cause the gel to emit radiation into said aqueous solution. The aqueous core of the apparatus functions not only to increase the efficiency of excitation, but also increases the contrast between excitation light and sample emission light. | 06-10-2010 |
20110308954 | Gel excitation apparatus - A gel excitation apparatus for exciting a gel that includes a container for holding an aqueous solution within which the gel can be positioned, at least one light source disposed whereas the light path is perpendicular to the optical axis, the container for irradiating the gel with radiation within at least a first wavelength band, the first wavelength band selected to excite the gel to cause the gel to emit radiation into said aqueous solution. The aqueous core of the apparatus has a low refractive index, thus retaining the first wavelength band selected within said aqueous core to excite the gel. Thus, the aqueous core functions not only to increase the efficiency of excitation, but also increases the contrast between excitation light and sample emission light by retaining the light within said aqueous core. | 12-22-2011 |
Patent application number | Description | Published |
20100033226 | Level shifter with output spike reduction - A level shifter, or method, producing a final output from a driver supplied by a high-side source driver providing VDD or common, and a low-side source driver providing common or VSS. A delay is introduced to prevent a source driver output at common from beginning to transition toward a supply rail until a delaying source driver at a rail begins transitioning toward common. The level shifter may be single-ended or differential, and the delaying source driver may be coupled to the same final output driver as is the delayed source driver, or may be coupled to a different final output driver. The level shifter may have a second level shifter front end stage, which may have high-side and low-side intermediate source driver outputs coupled by a capacitor, and/or may couple one of the supplies to all intermediate source drivers via a common impedance or current limit Zs. | 02-11-2010 |
20110156819 | Low-Noise High Efficiency Bias Generation Circuits and Method - A bias generation method or apparatus defined by any one or any practical combination of numerous features that contribute to low noise and/or high efficiency biasing, including: having a charge pump control clock output with a waveform having limited harmonic content or distortion compared to a sine wave; having a ring oscillator to generating a charge pump clock that includes inverters current limited by cascode devices and achieves substantially rail-to-rail output amplitude; having a differential ring oscillator with optional startup and/or phase locking features to produce two phase outputs suitably matched and in adequate phase opposition; having a ring oscillator of less than five stages generating a charge pump clock; capacitively coupling the clock output(s) to some or all of the charge transfer capacitor switches; biasing an FET, which is capacitively coupled to a drive signal, to a bias voltage via an “active bias resistor” circuit that conducts between output terminals only during portions of a waveform appearing between the terminals, and/or wherein the bias voltage is generated by switching a small capacitance at cycles of said waveform. A charge pump for the bias generation may include a regulating feed back loop including an OTA that is also suitable for other uses, the OTA having a ratio-control input that controls a current mirror ratio in a differential amplifier over a continuous range, and optionally has differential outputs including an inverting output produced by a second differential amplifier that optionally includes a variable ratio current mirror controlled by the same ratio-control input. The ratio-control input may therefore control a common mode voltage of the differential outputs of the OTA. A control loop around the OTA may be configured to control the ratio of one or more variable ratio current mirrors, which may particularly control the output common mode voltage, and may control it such that the inverting output level tracks the non-inverting output level to cause the amplifier to function as a high-gain integrator. | 06-30-2011 |
20110169550 | Method and Apparatus for Use in Improving Linearity of MOSFETs Using an Accumulated Charge Sink - A method and apparatus for use in improving the linearity characteristics of MOSFET devices using an accumulated charge sink (ACS) are disclosed. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one exemplary embodiment, a circuit having at least one SOI MOSFET is configured to operate in an accumulated charge regime. An accumulated charge sink, operatively coupled to the body of the SOI MOSFET, eliminates, removes or otherwise controls accumulated charge when the FET is operated in the accumulated charge regime, thereby reducing the nonlinearity of the parasitic off-state source-to-drain capacitance of the SOI MOSFET. In RF switch circuits implemented with the improved SOI MOSFET devices, harmonic and intermodulation distortion is reduced by removing or otherwise controlling the accumulated charge when the SOI MOSFET operates in an accumulated charge regime. | 07-14-2011 |
20110227637 | Method and Apparatus Improving Gate Oxide Reliability by Controlling Accumulated Charge - A method and apparatus are disclosed for use in improving the gate oxide reliability of semiconductor-on-insulator (SOI) metal-oxide-silicon field effect transistor (MOSFET) devices using accumulated charge control (ACC) techniques. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one embodiment, a circuit comprises a MOSFET, operating in an accumulated charge regime, and means for controlling the accumulated charge, operatively coupled to the SOI MOSFET. A first determination is made of the effects of an uncontrolled accumulated charge on time dependent dielectric breakdown (TDDB) of the gate oxide of the SOI MOSFET. A second determination is made of the effects of a controlled accumulated charge on TDDB of the gate oxide of the SOI MOSFET. The SOI MOSFET is adapted to have a selected average time-to-breakdown, responsive to the first and second determinations, and the circuit is operated using techniques for accumulated charge control operatively coupled to the SOI MOSFET. In one embodiment, the accumulated charge control techniques include using an accumulated charge sink operatively coupled to the SOI MOSFET body. | 09-22-2011 |
20120169398 | Method and Apparatus for Use in Improving Linearity of MOSFETs Using an Accumulated Charge Sink - A method and apparatus for use in improving the linearity characteristics of MOSFET devices using an accumulated charge sink (ACS) are disclosed. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one exemplary embodiment, a circuit having at least one SOI MOSFET is configured to operate in an accumulated charge regime. An accumulated charge sink, operatively coupled to the body of the SOI MOSFET, eliminates, removes or otherwise controls accumulated charge when the FET is operated in the accumulated charge regime, thereby reducing the nonlinearity of the parasitic off-state source-to-drain capacitance of the SOT MOSFET. In RF switch circuits implemented with the improved SOI MOSFET devices, harmonic and intermodulation distortion is reduced by removing or otherwise controlling the accumulated charge when the SOI MOSFET operates in an accumulated charge regime. | 07-05-2012 |
20130293280 | Method and Apparatus for use in Improving Linearity of MOSFETs using an Accumulated Charge Sink - A method and apparatus for use in improving the linearity characteristics of MOSFET devices using an accumulated charge sink (ACS) are disclosed. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one exemplary embodiment, a circuit having at least one SOI MOSFET is configured to operate in an accumulated charge regime. An accumulated charge sink, operatively coupled to the body of the SOI MOSFET, eliminates, removes or otherwise controls accumulated charge when the FET is operated in the accumulated charge regime, thereby reducing the nonlinearity of the parasitic off-state source-to-drain capacitance of the SOI MOSFET. In RF switch circuits implemented with the improved SOI MOSFET devices, harmonic and intermodulation distortion is reduced by removing or otherwise controlling the accumulated charge when the SOI MOSFET operates in an accumulated charge regime. | 11-07-2013 |
20140055194 | Low Noise Charge Pump Method and Apparatus - A charge pump method and apparatus is described having various aspects. Noise injection from a charge pump to other circuits may be reduced by limiting both positive and negative clock transition rates, as well as by limiting drive currents within clock generator driver circuits, and also by increasing a control node AC impedance of certain transfer capacitor coupling switches. A single-phase clock may be used to control as many as all active switches within a charge pump, and capacitive coupling may simplify biasing and timing for clock signals controlling transfer capacitor coupling switches. Any combination of such aspects of the method or apparatus may be employed to quiet and/or simplify charge pump designs over a wide range of charge pump architectures. | 02-27-2014 |
20140167834 | Method and Apparatus Improving Gate Oxide Reliability by Controlling Accumulated Charge - A method and apparatus are disclosed for use in improving the gate oxide reliability of semiconductor-on-insulator (SOI) metal-oxide-silicon field effect transistor (MOSFET) devices using accumulated charge control (ACC) techniques. The method and apparatus are adapted to remove, reduce, or otherwise control accumulated charge in SOI MOSFETs, thereby yielding improvements in FET performance characteristics. In one embodiment, a circuit comprises a MOSFET, operating in an accumulated charge regime, and means for controlling the accumulated charge, operatively coupled to the SOI MOSFET. A first determination is made of the effects of an uncontrolled accumulated charge on time dependent dielectric breakdown (TDDB) of the gate oxide of the SOI MOSFET. A second determination is made of the effects of a controlled accumulated charge on TDDB of the gate oxide of the SOI MOSFET. The SOI MOSFET is adapted to have a selected average time-to-breakdown, responsive to the first and second determinations, and the circuit is operated using techniques for accumulated charge control operatively coupled to the SOI MOSFET. In one embodiment, the accumulated charge control techniques include using an accumulated charge sink operatively coupled to the SOI MOSFET body. | 06-19-2014 |
20150015321 | Circuit and Method for Controlling Charge Injection in Radio Frequency Switches - A circuit and method for controlling charge injection in a circuit are disclosed. In one embodiment, the circuit and method are employed in a semiconductor-on-insulator (SOI) Radio Frequency (RF) switch. In one embodiment, an SOI RF switch comprises a plurality of switching transistors coupled in series, referred to as “stacked” transistors, and implemented as a monolithic integrated circuit on an SOI substrate. Charge injection control elements are coupled to receive injected charge from resistively-isolated nodes located between the switching transistors, and to convey the injected charge to at least one node that is not resistively-isolated. In one embodiment, the charge injection control elements comprise resistors. In another embodiment, the charge injection control elements comprise transistors. A method for controlling charge injection in a switch circuit is disclosed whereby injected charge is generated at resistively-isolated nodes between series coupled switching transistors, and the injected charge is conveyed to at least one node of the switch circuit that is not resistively-isolated. | 01-15-2015 |
Patent application number | Description | Published |
20100269817 | Concentrating Solar Energy System - Systems and methods for concentrating solar energy in the high earth atmosphere and transmitting the concentrated solar energy to the earth's surface. A system includes a light weight solar concentrator, supported by a light weight, rigid, buoyant, structure ( | 10-28-2010 |
20100319680 | Concentrating Solar Energy System for Multiple Uses - Systems and methods for concentrating solar energy in the high earth atmosphere and transmitting the concentrated solar energy to the earth's surface. A system includes a light weight solar concentrator, supported by a light weight, rigid, buoyant, structure ( | 12-23-2010 |
20110090710 | High Efficiency Light Pipe - Apparatus and method for transmitting concentrated light including concentrated solar energy over long distances, in particular from the stratosphere to earth's surface. The apparatus consists of a hollow gas tight tube light pipe ( | 04-21-2011 |
20120080161 | Thermal storage system - Apparatus and method for efficiently storing thermal energy, in particular thermal energy transferred from a concentrated solar energy receiver. The apparatus consists of a collection of modular thin walled tube pressure vessels enclosing solid sensible heat thermal storage elements. The high temperature solid is separated from the thin wall by thermal insulation and two thin gaps that carry the cold in and cold out high-pressure working fluids. Hot in and hot out working fluids circulate in counter flow channels within the solid sensible heat thermal storage elements. The solar receiver can also be modular to match the thermal storage elements, facilitating manufacturing and on site assembly. The design enables scalable thermal storage and concurrent thermal charging and discharging with no circuit switching between charge and discharge. | 04-05-2012 |
20140238460 | STRATOSPHERE TETHERED PHOTOVOLTAIC POWER PLATFORM - The present invention is realized by apparatus and methods for placing a large utility scale photovoltaic array in the low stratosphere of earth's atmosphere at an altitude of about 20km, above clouds, moisture, dust, and wind. This is accomplished using a large light-weight, rigid, buoyant structure to support the large photovoltaic array. Long, strong and light tethers connect the buoyant structure to the ground and hold it in position against wind forces. The electricity output from the photovoltaic array is then coupled to high voltage transmission lines which connect from the platform to the earth's surface. The electricity is then transmitted through the high voltage transmission lines to the earth's surface where it is connected to the electrical supply grid and provides lower cost, more reliable electricity. | 08-28-2014 |
20140270795 | Stratosphere Tethered Platform for multiple uses - The present invention is realized by apparatus and methods for placing a large rigid buoyant platform in the low stratosphere of earth's atmosphere at an altitude of about 20 km, above clouds, moisture, dust, and wind. The platform can serve several uses, either individually or in any combination. These uses include uninterrupted radio and light communications, radar and optical observation including very powerful radars and solar power electricity generation. Long, strong and light tethers connect the buoyant structure to the ground which hold it in position against wind forces. The electricity output from a photovoltaic array is used to power platform uses and can also be coupled to high voltage transmission lines which transmit power from the platform to the earth's surface during daylight hours. Power can also be transmitted up to the platform during darkness to power facilities mounted on the platform ensuring continuous operation. | 09-18-2014 |
Patent application number | Description | Published |
20080319175 | Transthyretin Stabilization - Dibenzofuran-4,6-dicarboxylic acid core structures having an aromatic substituent appended onto the at the C1 position using three different types of linkages are disclosed herein and shown to afford exceptional amyloidogenesis inhibitors that display increased affinity and greatly increased binding selectivity to TTR over all the other plasma proteins, relative to lead compound 1. It is further disclosed herein that these compounds function by imposing kinetic stabilization on the TTR tetramer. | 12-25-2008 |
20090054629 | Inhibitors of Transthyretin Amyloid Fibril Formation - Bisaryloxime ethers and bisarylhydroazones are shown to be effective for inhibiting formation of amyloid fibrils of transthyretin. | 02-26-2009 |
20100120919 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES - Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed. | 05-13-2010 |
20120065237 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES - Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed. | 03-15-2012 |
20130034547 | RELIABLE STABILIZATION OF N-LINKED POLYPEPTIDE NATIVE STATES WITH ENHANCED AROMATIC SEQUONS LOCATED IN POLYPEPTIDE TIGHT TURNS - A chimeric therapeutic polypeptide of a pre-existing therapeutic polypeptide is disclosed, as are a method of enhancing folded stabilization and a pharmaceutical composition of the glycosylated chimer. The pre-existing and chimeric polypeptides have substantially the same length, substantially the same amino acid residue sequence, and exhibit at least one tight turn containing a sequence of four to about seven amino acid residues in which at least two amino acid side chains extend on the same side of the tight turn and are within less than about 7 Å of each other. The chimeric therapeutic polypeptide has the sequon Aro-(Xxx)n-(Zzz)p-Asn-Yyy-Thr/Ser (SEQ ID NO:001) within that tight turn sequence such that the side chains of the Aro, Asn and Thr/Ser amino acid residues project on the same side of the turn and are within less than about 7 Å of each other. That sequon is absent from the pre-existing therapeutic polypeptide. | 02-07-2013 |
20140134753 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES - Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed. | 05-15-2014 |
Patent application number | Description | Published |
20090304751 | VAULT COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIA GENITAL INFECTION - Methods and compositions are provided herein for immunizing a subject against Chlamydial genital infection by administering to the subject an effective amount of a Chlamydial immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. In some aspects, the vault-like-particles are administered to the nasal mucosa. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity at mucosal surfaces while reducing inflammation associated with | 12-10-2009 |
20120141534 | Vault Compositions for Immunization Against Chlamydia Genital Infection - Methods and compositions are provided herein for immunizing a subject against Chlamydial genital infection by administering to the subject an effective amount of a Chlamydial immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. In some aspects, the vault-like-particles are administered to the nasal mucosa. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity at mucosal surfaces while reducing inflammation associated with | 06-07-2012 |
20130078273 | Vault Compositions For Immunization - Methods and compositions are provided herein for immunizing a subject by administering to the subject an effective amount of an immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity. | 03-28-2013 |
20130122037 | Vault Compositions for Immunization - Methods and compositions are provided herein for immunizing a subject by administering to the subject an effective amount of an immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity. | 05-16-2013 |
20130344078 | EMP2 ANTIBODIES AND THEIR THERAPEUTIC USES - The present invention provides methods and compositions useful in the treatment or prevention of | 12-26-2013 |
20140072569 | EMP2 ANTIBODIES AND THEIR THERAPEUTIC USES - The present invention provides methods and compositions useful in the treatment or prevention of | 03-13-2014 |
20140377301 | Vault Compositions for Immunization - Methods and compositions are provided herein for immunizing a subject by administering to the subject an effective amount of an immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity. | 12-25-2014 |
Patent application number | Description | Published |
20100185612 | Method for Producing an Ordered Search List - The invention is directed to a method for producing, for example, a search results listing for educational content, where the listing is ordered based not only on content relevance to the search request, but also on the subscription status and entity affiliation of the user as related to the content. This places, near the top of the list, results that may be not only more relevant to the user, but those that may also be more efficiently accessed. For example, a method for an education-related content search, configured according to the invention, receives a login input from a user and extracts user data corresponding to the login input. Upon receiving a search request, the user data and the search request is transmitted, and an ordered search list that is ordered based on the user data is received. | 07-22-2010 |
20100191610 | METHOD FOR AUTOMATING A FUNDRAISER TO EFFECT A PURCHASE - The invention is directed to a method for completing an online purchase via a fundraiser implemented online. This allows for an efficient manner of receiving donations to provide funds for a desired purchase, where each donation may be directly channeled to the purchase balance. Once the balance is met, the purchase may be automatically effected. For example, a computer-implemented method for effecting a purchase, configured according to the invention, provides, in electronic digital form, a user interface to initiate a fundraiser to provide funds for the purchase. Upon receiving, in electronic digital form, a user input via the user interface, a fundraiser structure, in electronic digital form, may be created based on the user input to enable receipt of a donation to pay for a portion of the purchase. | 07-29-2010 |
20110119741 | Method for Conditionally Obtaining Files From a Local Appliance - The invention is directed to a method for allowing a user at a client device to conditionally obtain files from either a server device located at, for example, a data center, or an appliance such as a local cache. Should the local appliance be accessible by the client at the time of the user's download request, the server may redirect the download request to the appliance. Otherwise, the file may be downloaded directly from the server. For example, a method configured according to the invention may receive, at a server device, login data from a client device, the login data being input by a user. An affiliated entity of the user based on the login data may be determined, after which an appliance status of the affiliated entity may be determined. A download process according to the appliance status may then be initiated. | 05-19-2011 |
Patent application number | Description | Published |
20090263896 | METHODS FOR PURIFYING ENDODERM AND PANCREATIC ENDODERM CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS - The present disclosure relates to compositions and methods comprising cell surface markers for hES-derived cells, in particular, endoderm lineage cells including pancreatic endoderm-type cells, derived from hES cells. | 10-22-2009 |
20100041150 | EXPANSION OF DEFINITIVE ENDODERM CELLS - Disclosed herein are cell cultures comprising expanded definitive endoderm cells as well as methods for expanding definitive endoderm cells in culture. | 02-18-2010 |
20100112691 | Stem Cell Aggregate Suspension Compositions and Methods of Differentiation Thereof - The present invention relates to methods for production of undifferentiated or differentiated embryonic stem cell aggregate suspension cultures from undifferentiated or differentiated embryonic stem cell single cell suspensions and methods of differentiation thereof. | 05-06-2010 |
20100124564 | ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS - The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation. | 05-20-2010 |
20110280915 | ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS - The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation. | 11-17-2011 |
20120045830 | STEM CELL AGGREGATE SUSPENSION COMPOSITIONS AND METHODS OF DIFFERENTIATION THEREOF - The present invention relates to methods for production of undifferentiated or differentiated embryonic stem cell aggregate suspension cultures from undifferentiated or differentiated embryonic stem cell single cell suspensions and methods of differentiation thereof. | 02-23-2012 |
20130122520 | METHODS FOR PURIFYING ENDODERM AND PANCREATIC ENDODERM CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS - The present disclosure relates to compositions and methods comprising cell surface markers for hES-derived cells, in particular, endoderm lineage cells including pancreatic endoderm-type cells, derived from hES cells. | 05-16-2013 |
20130164787 | CELL COMPOSITIONS DERIVED FROM DEDIFFERENTIATED REPROGRAMMED CELLS - Disclosed herein are cell culture compositions, for example, pancreatic cell culture compositions, derived from dedifferentiated human reprogrammed pluripotent stem cells, such as induced pluripotent stem (iPS) cells, and methods for producing and using such cell culture compositions. | 06-27-2013 |
20130209425 | ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS - The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation. | 08-15-2013 |
20140193905 | EXPANSION OF DEFINITIVE ENDODERM CELLS - Disclosed herein are cell cultures comprising expanded definitive endoderm cells as well as methods for expanding definitive endoderm cells in culture. | 07-10-2014 |
Patent application number | Description | Published |
20090104664 | Use of Molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 04-23-2009 |
20120009670 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 01-12-2012 |
20130189776 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 07-25-2013 |
20130330819 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 12-12-2013 |
20130330820 | Use of Molecular Chaperones for the Enhanced Production of Secreted, Recombinant Proteins in Mammalian Cells - The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein. | 12-12-2013 |
Patent application number | Description | Published |
20090136346 | Vertical axis wind turbine - A vertical axis wind turbine having a plurality of upright airfoils pivotally engaged. A continuous adjustment of the angle of attack of the airfoils to oncoming wind is provided by rotation of a control plate connected to the vanes which are mounted upon a rotating drive plate. A vane can be employed to rotate the control plate to affect the continuous adjustment of the airfoils. | 05-28-2009 |
20100072818 | Electrical Energy Storage and Retrieval System - A system and method to efficiently store and convert erratic wind and solar electrical energy production to a source of reliable standard AC electrical power by means of an electric motor operatively engaged to power a pump. The pump in a sealed communication with a reservoir cavity evacuates air from the cavity to store the generated energy as potential energy in the form of a pressure differential with ambient atmosphere. Regulated air inflow into the evacuated cavity is employed to drive a generator or alternator to produce electric power which is synchronized with grid demand and communicated to the grid. | 03-25-2010 |
20110042959 | Wind Energy Conversion Apparatus - An apparatus and method to efficiently convert erratic wind energy to a source of reliable standard AC electrical power by means of a complex tower-mounted windmill operatively engaged to power a pump. The pump in a sealed communication with a chamber evacuates air from the chamber to store the wind-generated energy as potential energy in the form of a pressure differential with ambient atmosphere. Regulated air inflow into the evacuated chamber is employed to drive a generator to produce electric power which is synchronized with the grid on demand. | 02-24-2011 |
20120269629 | VERTICAL AXIS WIND TURBINE - A vertical axis wind turbine having a plurality of upright airfoils pivotally engaged. A continuous adjustment of the angle of attack of the airfoils to oncoming wind is provided by rotation of a control plate connected to the vanes which are mounted upon a rotating drive plate. A vane can be employed to rotate the control plate to affect the continuous adjustment of the airfoils. | 10-25-2012 |
20140086745 | Vertical Axis Wind Turbine - A vertical axis wind turbine having a plurality of upright airfoils pivotally engaged. A continuous adjustment of the angle of attack of the airfoils to oncoming wind is provided by rotation of a control plate connected to the vanes which are mounted upon a rotating drive plate. A vane can be employed to rotate the control plate to affect the continuous adjustment of the airfoils. | 03-27-2014 |
Patent application number | Description | Published |
20090158042 | Managed Access Point Protocol - Methods, apparatuses and systems facilitating deployment and configuration of managed access points in hierarchical wireless network systems. An embodiment of the invention facilitates deployment and configuration of conventional, substantially autonomous access points operating in connection with a central management node, such as a server or appliance. In another embodiment, the present invention facilitates deployment and configuration of light-weight access points in a hierarchical wireless network system. In one embodiment, the present invention also provides a streamlined encryption key exchange protocol adapted to hierarchical wireless network system architectures. | 06-18-2009 |
20120188993 | Managed Access Point Protocol - Methods, apparatuses and systems facilitating deployment and configuration of managed access points in hierarchical wireless network systems. An embodiment of the invention facilitates deployment and configuration of conventional, substantially autonomous access points operating in connection with a central management node, such as a server or appliance. In another embodiment, the present invention facilitates deployment and configuration of light-weight access points in a hierarchical wireless network system. In one embodiment, the present invention also provides a streamlined encryption key exchange protocol adapted to hierarchical wireless network system architectures. | 07-26-2012 |
20130343367 | Managed Access Point Protocol - Methods, apparatuses and systems facilitating deployment and configuration of managed access points in hierarchical wireless network systems. An embodiment of the invention facilitates deployment and configuration of conventional, substantially autonomous access points operating in connection with a central management node, such as a server or appliance. In another embodiment, the present invention facilitates deployment and configuration of light-weight access points in a hierarchical wireless network system. In one embodiment, the present invention also provides a streamlined encryption key exchange protocol adapted to hierarchical wireless network system architectures. | 12-26-2013 |
Patent application number | Description | Published |
20090268915 | Secure Creation and Management of Device Ownership Keys - Secure creation and management of device ownership keys. TPM ownership keys are generated by cryptographically combining manufacturer information with device specific information. Ownership keys are established in the TPM containing device. The manufacturer retains necessary information to reconstruct the ownership key if needed. | 10-29-2009 |
20100113084 | POWER SAVING IN WIRELESS NETWORKS - Power savings in a wireless digital network. In a network having a plurality of access nodes attached to a controller, access nodes are placed in reduced power states depending on network use or time. In a first embodiment, portions of an access node may be switched between normal and low power modes based on access node activity, or on command. In a second embodiment, the entire access node may be placed in a lower power mode, and awakened from this lower power mode by a LAN signal. A power manager monitors wireless network use to determine which access nodes connected to a controller are to be placed in a low power state. Calendar and time scheduling may also be used. | 05-06-2010 |
20100131694 | Secure Boot ROM Emulation - Secure boot ROM emulation with locking storage device. A locking storage device is provided by combining a nonvolatile memory device such as flash or EEPROM with one-shot locking logic which write enables at least a portion of the nonvolatile memory device upon power cycling of the overall digital device. This write enable is cleared during the stage 1 bootloader process, thus providing a protected update interval for updating a stage 2 bootloader once per power cycle. | 05-27-2010 |
20130179695 | VERIFYING AUTHENTICITY OF PLAYBACK DEVICE - One embodiment of the invention sets forth a mechanism for verifying the authenticity of a device before transmitting digital content to the device. In operation, the device stores a device key that is generated at manufacture-time using a pre-determined cryptographic key and the device identifier. In operation, the device generates a proof of possession from the application data and the stored device key. When verifying the device authenticity, a device key is derived from the master key and the device identifier then a proof of possession is derived from the derived device key and the application data obtained from the device. If the derived proof of possession matches the received proof of possession, then the authenticity of the device can be verified. | 07-11-2013 |
Patent application number | Description | Published |
20090006978 | ADAPTIVE ARTWORK FOR BANDWIDTH- AND/OR MEMORY- LIMITED DEVICES - Methods and apparatuses for adaptive presentation of graphical representations. | 01-01-2009 |
20120310894 | METHODS AND APPARATUS FOR INTERFACE IN MULTI-PHASE RESTORE - Methods and apparatus to restore resources to a device according to an order of the resources requested by a user are described. The restoration may be interrupted in response to a user request to update an order to restore remaining resources yet to restore. The remaining resources may be restored according to the updated order. | 12-06-2012 |
20120311366 | METHODS AND APPARATUS FOR POWER STATE BASED BACKUP - Methods and apparatus that receive, at a wireless device, power through wire or inductive pad are described. The received power is monitored to back up data from the device to a server in a network through an OTA (over the air) wireless interface. The data is transmitted to the server to back up the data on the device. While backing up the data, whether the power has been removed from the device is determined. The backing up of the data in the device can be terminated automatically and without user request, in response to the determination that the power has been removed. | 12-06-2012 |
20130086408 | METHODS AND APPARATUS FOR POWER STATE BASED BACKUP - Methods and apparatus that receive, at a wireless device, power through wire or inductive pad are described. The received power is monitored to back up data from the device to a server in a network through an OTA (over the air) wireless interface. The data is transmitted to the server to back up the data on the device. While backing up the data, whether the power has been removed from the device is determined. The backing up of the data in the device can be terminated automatically and without user request, in response to the determination that the power has been removed. | 04-04-2013 |
20140025521 | SECURING IN-APP PURCHASES - In one embodiment, a unique (or quasi unique) identifier can be received by an application store, or other on-line store, and the store can create a signed receipt that includes data desired from the unique identifier. This signed receipt is then transmitted to a device that is running the application obtained from the on-line store and the device can verify the receipt by deriving the unique (or quasi-unique) identifier from the signed receipt and comparing the derived identifier with the device identifier stored on the device, or the vendor identifier assigned to the application vendor. | 01-23-2014 |
20140082695 | SECURE ACCOUNT CREATION - In one embodiment, non-transitory computer-readable medium stores instructions for establishing a trusted two-way communications session for account creation for an online store, which include instructions for causing a processor to perform operations comprising retrieving and verifying a signed configuration file from a server, requesting a communication session using the configuration file, receiving a payload of account creation forms from a network client, signing the payload according to the server configuration file, and sending the signed payload containing account creation information to the server. In one embodiment, a computer-implemented method comprises analyzing timestamps for requests for data forms for supplying account creation information for evidence of automated account creation activity and rejecting the request for the locator of the second account creation form if evidence of automated account creation activity is detected. Methods for secure account authentication and asset purchase are also disclosed. | 03-20-2014 |
20140250015 | USER INTERFACE FOR APPLICATION MANAGEMENT FOR A MOBILE DEVICE - This specification describes technologies relating to user interfaces for mobile devices. In general, one aspect of the subject matter described in this specification can be embodied in methods that include the actions of receiving a touch input to access an application management interface on a mobile device; presenting an application management interface; receiving one or more inputs within the application management interface including an input to install a particular application; installing the selected application; and presenting the installed application. | 09-04-2014 |
20150073998 | Use of a Biometric Image in Online Commerce - An online store can transmit an online account token to an electronic device or to a biometric sensing device after a user successfully enters his or her account password. The electronic device or the biometric sensing device can countersign the online account token when the one or more biometric images match reference biometric images and the account password matches user identifier data stored in the electronic device or in the biometric sensing device. The countersigned online account token can then be transmitted to the online store. The user can then make one or more purchases after the online store receives the countersigned online account token. | 03-12-2015 |
Patent application number | Description | Published |
20100268623 | Purchase Handoff in a Travel Search Engine - A method and apparatus are provided for a dynamic information connection engine. User actions are detected on at least one client system. In response, a determination is made whether the user is searching for supported information. When the user is searching for supported information, information is extracted electronically from third party web sites, direct supplier connections, and intermediate databases. Potential information suppliers are automatically selected in response to the detected user search. Queries are formulated from the user search and transferred to each selected supplier over a network coupling. The queries include a request for information. Responses are received from the suppliers, and the responses are used to generate a result list for the user. The result list includes information and query status information. Further, an electronic link may be provided to a web site of each supplier from which the information was derived. | 10-21-2010 |
20120179578 | PURCHASE HANDOFF IN A TRAVEL SEARCH ENGINE - A method and apparatus are provided for a dynamic information connection engine. User actions are detected on at least one client system. In response, a determination is made whether the user is searching for supported information. When the user is searching for supported information, information is extracted electronically from third party web sites, direct supplier connections, and intermediate databases. Potential information suppliers are automatically selected in response to the detected user search. Queries are formulated from the user search and transferred to each selected supplier over a network coupling. The queries include a request for information. Responses are received from the suppliers, and the responses are used to generate a result list for the user. The result list includes information and query status information. Further, an electronic link may be provided to a web site of each supplier from which the information was derived. | 07-12-2012 |
20120179673 | PROFITABILITY BASED RANKING OF SEARCH RESULTS FOR LODGING RESERVATIONS - Method and apparatus for dynamic information connection search engine. User actions may be detected on at least one client system. Determination may be made whether the user is searching for supported information. When the user is searching for supported information, information may be extracted electronically from, e.g., third party websites, direct supplier connections, and/or intermediate databases. Suppliers may be automatically selected in response to the user search. Queries may be formulated from the user search and transferred to one or more selected suppliers over a network coupling (e.g., the Internet and/or intranet). Queries may include one or more requests for information. One or more responses may be received from suppliers, and responses may be used to generate results for the user. Results may include information and/or query status information. An electronic link may be provided to a website of one or more suppliers from which information was derived. | 07-12-2012 |
20130246103 | PURCHASE HANDOFF IN A TRAVEL SEARCH ENGINE - A method and apparatus are provided for a dynamic information connection engine. User actions are detected on at least one client system. In response, a determination is made whether the user is searching for supported information. When the user is searching for supported information, information is extracted electronically from third party web sites, direct supplier connections, and intermediate databases. Potential information suppliers are automatically selected in response to the detected user search. Queries are formulated from the user search and transferred to each selected supplier over a network coupling. The queries include a request for information. Responses are received from the suppliers, and the responses are used to generate a result list for the user. The result list includes information and query status information. Further, an electronic link may be provided to a web site of each supplier from which the information was derived. | 09-19-2013 |
20130275425 | PROFITABILITY BASED RANKING OF SEACH RESULTS FOR LODGING RESERVATIONS - Method and apparatus for dynamic information connection search engine. User actions may be detected on at least one client system. Determination may be made whether the user is searching for supported information. When the user is searching for supported information, information may be extracted electronically from, e.g., third party websites, direct supplier connections, and/or intermediate databases. Suppliers may be automatically selected in response to the user search. Queries may be formulated from the user search and transferred to one or more selected suppliers over a network coupling (e.g., the Internet and/or intranet). Queries may include one or more requests for information. One or more responses may be received from suppliers, and responses may be used to generate results for the user. Results may include information and/or query status information. An electronic link may be provided to a website of one or more suppliers from which information was derived. | 10-17-2013 |
Patent application number | Description | Published |
20090048368 | POLYOLEFIN COMPOSITIONS COMPRISING BIO-BASED STARCH MATERIALS - Polyolefin compositions and methods of making and using the polyolefin compositions are provided. In a general embodiment, the present disclosure provides a composition comprising a polyolefin, a compatibilizer, a starch and a plasticizer. | 02-19-2009 |
20110269890 | BIODEGRADABLE NANOPOLYMER COMPOSITIONS AND BIODEGRADABLE ARTICLES MADE THEREOF - Biodegradable nanopolymer compositions and methods of making the compositions are provided. In a general embodiment, the present disclosure provides a biodegradable nanopolymer composition made from starting material comprising poly(lactic acid), co-polyester polymer with adipic acid compounded and nanoparticles of a mineral material such as silica and magnesium silicate. In addition, the present disclosure provides processes for making the biodegradable nanopolymer compositions as well as biodegradable articles made using the biodegradable nanopolymer compositions such as molded, formed and extruded articles. | 11-03-2011 |
20140011921 | POLYOLEFIN COMPOSITIONS COMPRISING BIO-BASED STARCH MATERIALS - Polyolefin compositions and methods of making and using the polyolefin compositions are provided. In a general embodiment, the present disclosure provides a composition comprising a polyolefin, a compatibilizer, a starch and a plasticizer. | 01-09-2014 |
20140273169 | POLYMER COMPOSITIONS COMPRISING ALGAE MATERIALS - Polymer compositions and methods of making and using the polymer compositions are provided. In a general embodiment, the present disclosure provides a composition comprising a polymer, a compatibilizer and an algae product. | 09-18-2014 |