Patent application number | Description | Published |
20100008864 | AROMATIC MULTIMERS - The present invention relates to novel compounds of formula (I) and (II), compositions comprising compounds of formula (II) and their use as contrast agents in magnetic resonance (MR) imaging (MRI) and MR spectroscopy (MRS). | 01-14-2010 |
20110070161 | ACTIVE ENANTIOMER - The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided. | 03-24-2011 |
20110110865 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) - The present invention relates to chelators, in particular to chelators which are capable of forming complexes, i.e. paramagnetic chelates, with paramagnetic metal ions. The invention also relates to said paramagnetic chelates, said paramagnetic chelates linked to other molecules and their use as contrast agents in magnetic resonance imaging (MRI). | 05-12-2011 |
20110200536 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) - The present invention relates to chelators, in particular to chelators which are capable of forming complexes, i.e. paramagnetic chelates, with paramagnetic metal ions. The invention also relates to said paramagnetic chelates, said paramagnetic chelates linked to other molecules and their use as contrast agents in magnetic resonance imaging (MRI). | 08-18-2011 |
20120020884 | INDOLE DERIVATIVES - An indole-based in vivo imaging agent is provided by the present invention that binds with high affinity to PBR, has good uptake into the brain following administration, and which has good selective binding to PBR. The invention also includes a precursor compound useful in the synthesis of the in vivo imaging agent of the invention, as well as a method for synthesis of said in vivo imaging agent comprising use of said precursor compound, and a kit for carrying out said method. Also provided is a cassette for automated synthesis of the in vivo imaging agent. Further aspects of the invention include a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, and methods for the use of said in vivo imaging agent. | 01-26-2012 |
20140364615 | INDOLE DERIVATIVES - An indole-based in vivo imaging agent is provided by the present invention that binds with high affinity to PBR, has good uptake into the brain following administration, and which has good selective binding to PBR. The invention also includes a precursor compound useful in the synthesis of the in vivo imaging agent of the invention, as well as a method for synthesis of said in vivo imaging agent comprising use of said precursor compound, and a kit for carrying out said method. Also provided is a cassette for automated synthesis of the in vivo imaging agent. Further aspects of the invention include a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, and methods for the use of said in vivo imaging agent. | 12-11-2014 |
Patent application number | Description | Published |
20090296685 | User-Mode Prototypes in Kernel-Mode Protocol Stacks - Methods of enabling user-mode prototypes in kernel-mode protocol stacks are described. A protocol stack comprises a set of kernel-mode modules. The protocol stack defines a data path for packets. At least one interception point is defined in a kernel-mode module at which a packet can be intercepted and/or inserted. In an embodiment, each packet intercepted at the interception point, or a copy of said packet, is sent to a user-mode module. The user-mode module processes the packet in some way and then returns the packet to the same, or a different, interception point in the data path. In this way, a user-mode module (which is easier to program) can be used to prototype functionality of a kernel-mode module without requiring kernel-mode code to be written. | 12-03-2009 |
20110013516 | Control of Background Data Transfers - Control of background data transfers is described. In an embodiment, a background data transfer is controlled at a receiver node by measuring a time period taken to receive from a sender node a data sequence of the same size as a receive window. The time period is used to evaluate available network capacity, and the network capacity used to calculate a new window size. The new window size is applied and communicated to the sender node. In another embodiment, a background data transfer is controlled at a receiver node by measuring a quantity of data received from a sender node during a first control interval. The measured quantity is used to evaluate available network capacity, and the network capacity used to calculate a new receive window size and a second control interval duration. The new window size is applied for the second control interval, and communicated to the sender node. | 01-20-2011 |
20120158998 | API Supporting Server and Key Based Networking - An application programming interface (API) supporting server and key based networking is described. In an embodiment, the API receives either a key or a server address from a service running on a server in a direct-connect topology and returns data which identifies suitable next hops for transmission of a packet of data which has a destination of the received server address or of a server address which is encoded within the received key. In another embodiment, the key also encodes information specifying alternative server addresses for use in the event that the original server is unreachable. This information may also be used to define servers for replication of the key. A further embodiment describes a method of queuing packets for transmission against multiple links, where the packet is transmitted on the first available link and at this time is removed from the queues for the other links. | 06-21-2012 |
20140330937 | END-TO-END CLASSIFICATION OF STORAGE TRAFFIC STREAMS - Methods of classifying a storage traffic stream in a shared storage network are described. In an embodiment, an identifier for the entity generating the stream is generated, where this entity may, for example, indicate a virtual machine, program, session, physical machine, user or process. The identifier is then shared with at least one processing layer along a path of the storage traffic stream between the generating entity and the storage device which stores the file to which the traffic stream relates. In various embodiments, the identifier may then be used by any processing layers which receive it, to selectively handle traffic streams based on the generating entity. The identifier may be shared when the traffic stream is created or subsequently and in various embodiments, the identifier is shared in a second exchange of messages, following the creation of the traffic stream and prior to any other traffic. | 11-06-2014 |
20150081948 | CONTROLLING DATA STORAGE INPUT/OUTPUT REQUESTS - Controlling data storage input/output requests is described, for example, to apply a policy to an end-to-end flow of data input/output requests between at least one computing entity and at least one store. In various examples a plurality of queues are configured at one or more stages of the end-to-end flow and controlled to adhere to a policy. In examples, each stage has a control interface enabling it to receive and execute control instructions from a controller which may be centralized or distributed. For example, the control instructions comprise queuing rules and/or queue configurations. In various examples queues and queuing rules are dynamically created and revised according to feedback about any of: flow behavior, changes in policy, changes in infrastructure or other factors. In examples, high level identifiers of the flow endpoints are resolved, on a per stage basis, to low level identifiers suitable for use by the stage. | 03-19-2015 |
20150222523 | API Supporting Server and Key Based Networking - An application programming interface (API) supporting server and key based networking is described. In an embodiment, the API receives either a key or a server address from a service running on a server in a direct-connect topology and returns data which identifies suitable next hops for transmission of a packet of data which has a destination of the received server address or of a server address which is encoded within the received key. In another embodiment, the key also encodes information specifying alternative server addresses for use in the event that the original server is unreachable. This information may also be used to define servers for replication of the key. A further embodiment describes a method of queuing packets for transmission against multiple links, where the packet is transmitted on the first available link and at this time is removed from the queues for the other links. | 08-06-2015 |
Patent application number | Description | Published |
20100027588 | Content Transfer - Content transfer between nodes in a communications network is required in many situations. For example, between fixed nodes in a data center, between a fixed node such as a base station and a mobile node such as a mobile telephone and between mobile nodes themselves such as personal digital assistants. In an embodiment a content transfer process for use between nodes where one node knows the size of content to be transferred is described. For example, a file is divided into blocks to be sent between the nodes. A node receiving a block keeps a record of the received blocks and sends that record to the sending node at certain times. By controlling the times at which the records are sent the number of messages that need to be sent to transfer the records is low and the blocks are transferred in an efficient manner. | 02-04-2010 |
20100030840 | Content Discovery and Transfer Between Mobile Communications Nodes - Content discovery and content transfer between mobile communications nodes is often required, for example, to synchronize maps, traffic hot spot information and the like for vehicle mounted satellite navigation devices, pedestrian hand-held personal digital assistants and other mobile communications nodes. In an embodiment, content discovery processes using data structures designed in particular ways and sent using a single packet enable nodes to identify files to be transferred whilst keeping overheads down. In an embodiment a first and a second data structure are used, each being formed from slightly different information about a subset of the files to be synchronized. In another embodiment a single tree-based data structure is used. A process for transferring data between two mobile communications nodes is also described. | 02-04-2010 |
20120072478 | Content Discovery and Transfer Between Mobile Communications Nodes - Content discovery and content transfer between mobile communications nodes is often required, for example, to synchronize maps, traffic hot spot information and the like for vehicle mounted satellite navigation devices, pedestrian hand-held personal digital assistants and other mobile communications nodes. In an embodiment, content discovery processes using a tree-based data structure for transferring data between two mobile communication nodes is described. | 03-22-2012 |
20120151292 | Supporting Distributed Key-Based Processes - Supporting distributed key-based processes is described. In an embodiment, servers at a data center provide a key-based process for carrying out computationally expensive tasks and are connected using point to point connections in a geometric topology such as a torus. In an example, aggregation trees are built on top of the geometric topology of the data center, each aggregation tree being a sequence of servers in the data center that forms a tree structure. In an embodiment packets of data are sent from the leaves of the trees to the root and at each server along the tree the packets are aggregated using a combiner function of the key-based process. In an embodiment, if a server fails, the trees are dynamically recomputed and a recovery phase is triggered to resend any packets lost at the failed server. In some embodiments, packets are scheduled by inspecting the content of the packets. | 06-14-2012 |
Patent application number | Description | Published |
20120122806 | METHOD OF LOWERING GLYCEMIC INDEX OF FOODS - A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the animal or human in conjunction with the food, wherein the flavonoids are selected from luteolin, apigenin, tricin and their pharmaceutically acceptable analogues and derivatives. | 05-17-2012 |
20140342042 | METHOD OF LOWERING GLYCEMIC INDEX OF FOODS - A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the animal or human in conjunction with the food, wherein the flavonoids are selected from luteolin, apigenin, tricin and their pharmaceutically acceptable analogues and derivatives. | 11-20-2014 |
20140343002 | METHOD OF LOWERING GLYCEMIC INDEX OF FOODS - A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the animal or human in conjunction with the food, wherein the flavonoids are selected from luteolin, apigenin, tricin and their pharmaceutically acceptable analogues and derivatives. | 11-20-2014 |
Patent application number | Description | Published |
20100298502 | MODIFICATION OF POLYOLEFINS - The invention provides a process for increasing the melt flow index of a polyolefin, the process comprising using a melt mixing device to melt mix the polyolefin in contact with oxygen and a transition metal catalyst having a redox potential ranging from 0 to 2 volts, wherein oxygen is introduced to the melt mixing device, and wherein the transition metal catalyst in contact with the polyolefin forms at least part of a component of the melt mixing device. | 11-25-2010 |
20110243884 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES - The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone. | 10-06-2011 |
20120252967 | POLYURETHANES - The present invention relates to a polyurethane polymer comprising as part of its polymer backbone an α-oxy carbonyl moiety of general formula (I), where A and B represent the remainder of the polymer backbone and are the same or different, and R is an optionally substituted aliphatic hydrocarbon having three or more carbon atoms. | 10-04-2012 |
20120264988 | CINEOLE - The present invention relates to a process for producing unsaturated cyclic and/or aromatic compounds from 1,8-cineole, the process comprising pyrolysing 1,8-cineole in the presence of gamma-alumina supported transition metal catalyst. | 10-18-2012 |
20140046018 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES - The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone. | 02-13-2014 |
20140120058 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES - The present invention relates in general to polymer-drug conjugates. In particular, the invention relates to polymer-drug conjugates wherein the conjugated drugs are selected from prostaglandins and substituted prostaglandins, to a method of delivering such prostaglandin drugs to a subject, to a sustained drug delivery system comprising the polymer-drug conjugates, to a method of preparing the polymer-drug conjugates, and to an implant comprising the polymer-drug conjugates. The polymer-drug conjugates may be useful for delivering prostaglandins and substituted prostaglandins for the treatment of glaucoma. | 05-01-2014 |