Patent application number | Description | Published |
20080234235 | Synthesis of Polyanhydrides - The present invention provides a method for forming compounds of Formula | 09-25-2008 |
20090035248 | Fast Degrading Polymers - The invention provides polyanhydrides that degrade in less than 60 hours following topical administration to deliver biologically active compounds. | 02-05-2009 |
20090175932 | MICELLE ASSEMBLIES - The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. Also, the invention encompasses compounds of the formula: A-X-Y-Z-R | 07-09-2009 |
20100074937 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS - An aromatic polyanhydride comprising a repeating unit having the structure | 03-25-2010 |
20110022161 | IODINATED POLYMERS - The invention provides medical devices that comprise an iodinated polymer and that can be viewed using X-Ray imaging techniques. The invention also provides novel iodinated polymers that can be incorporated into or coated on medical devices. | 01-27-2011 |
20120022159 | AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF - Biomedical uses of amphiphilic macromolecules include the use of such macromolecules in the form of nanoparticle formulations for the sequestration and/or removal of LDL, and for the treatment and prevention of atherosclerosis and atherosclerotic development. The invention also provides the use of amphiphilic macromolecule encapsulates for treating diseases including cancer and inflammation, as well as targeted amphiphilic macromolecules and their use in therapy. | 01-26-2012 |
20140328763 | BIOACTIVE AMPHIPHILIC POLYMER STABILIZED NANOPARTICLES WITH ENHANCED STABILITY AND ACTIVITY - The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors. | 11-06-2014 |
Patent application number | Description | Published |
20100272670 | BIODEGRADABLE POLYANHYDRIDES WITH NATURAL BIOACTIVE MOLECULES - The invention provides polymers that include a biologically active molecule and methods for their use. | 10-28-2010 |
20100291180 | NERVE GUIDANCE TUBES - Provided herein are cell guidance tubes and methods for their use. | 11-18-2010 |
20100291181 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH - The invention provides therapeutic devices comprising a polymeric anti-inflammatory agent that biodegrades to release anti-inflammatory agents. The therapeutic devices are useful for repair and regeneration of a variety of injured tissues. | 11-18-2010 |
20110229416 | AMPHIPHILIC MACROMOLECULES FOR SOLUBILIZING NANOCRYSTALS - Certain embodiments of the invention provide amphiphilic macromolecules and nanocrystals encapsulated by amphiphilic macromolecules. Additionally, certain embodiments of the invention also provide nanocrystals that are water-solubilzed using functionalized AMs capable of coordinating to the nanocrystal surface. | 09-22-2011 |
20120039983 | AMPHIPHILIC MACROMOLECULE-LIPID COMPLEXES - The invention provides amphiphilic macromolecule (AM)-lipid complexes, methods of making the complexes, and methods of using the complexes. | 02-16-2012 |
20120058155 | SLOW-DEGRADING POLYMERS FOR UNDELAYED AND SUSTAINED DRUG DELIVERY - The invention provides polymers and methods for their use. Certain embodiments of the invention provide slow degrading microspheres for undelayed and sustained drug delivery. | 03-08-2012 |
20120219598 | POLYMERIC MICELLES FOR REDUCING LDL IN VIVO - The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. The invention also includes compounds of the formula I: | 08-30-2012 |
20120225926 | AMPHIPHILIC MACROMOLECULES FOR NUCLEIC ACID DELIVERY - The invention provides amphiphilic macromolecules that are useful for delivering nucleic acids to cells and that are useful as delivery agents for gene therapy. | 09-06-2012 |
20130022569 | HYDROGELS - The invention provides hydrogels comprising bioactive-based poly(anhydride-ester)s (PAEs) and methods for use thereof. | 01-24-2013 |
20130217753 | AMPHIPHILIC MACROMOLECULES FOR NUCLEIC ACID DELIVERY - The invention provides amphiphilic macromolecules that are useful for delivering nucleic acids to cells and that are useful as delivery agents for gene therapy. | 08-22-2013 |
20140030341 | POLYMERS AND METHODS FOR THE TREATMENT OF PAIN - Polymers, microspheres, and associated methods are presented for the treatment of chronic and acute pain. An anhydride polymer comprising a biodegradable backbone that comprises one or more pendant residues of a non-steroidal anti-inflammatory (NSAID). NSAIDs may be incorporated in to the polymers as pendant groups that are not part of the polymer backbone. The polymer comprises repeating units that form the biodegradable backbone, wherein in each repeating unit comprises a pendant residue of the NSAID. | 01-30-2014 |
20140050692 | POLYESTERS AND METHODS OF USE THEREOF - The invention provides polymers and methods for the treatment of pain and inflammation. | 02-20-2014 |
20140120057 | POLYMERS AND METHODS THEREOF FOR WOUND HEALING - Certain embodiments of the invention provide a copolymer having a backbone, wherein the backbone comprises a) one or more units that comprise a group that will yield a biologically active agent upon hydrolysis of the backbone; and b) one or more units of formula (II): | 05-01-2014 |
20140271864 | THERAPEUTIC COMPOSITIONS FOR BONE REPAIR - Individuals having diabetes are more prone to fractures, periodontitis, and other bone related issues as compared to healthy individuals. Furthermore, bone healing in diabetic patients is prolonged. The invention provides a method for decreasing bone resorption or increasing bone formation or promoting bone healing in diabetic patients. In particular, a biodegradeable polymer, such as a polyanhydride salicylate is administered at or near a bone defect site, and upon hydrolysis of the polymer will releases biologically active salicylic acid. | 09-18-2014 |