Horton, GB
Ben Horton, Cobham GB
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20150096194 | Ice Grips - An ice grip is adapted to be worn on a user's foot and includes a sole having a ground engaging surface ( | 04-09-2015 |
David Horton, Hampshire GB
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20130128955 | BITRATE DISTRIBUTION - There is provided a method of processing video information, the method comprising encoding ( | 05-23-2013 |
David A. Horton, Hampshire GB
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20150041381 | CHROMATOGRAPHY COLUMN - Chromatography columns having at least one assembly comprising a backing plate adhesively bound to a flow distributor, and methods of making and using the columns are disclosed. | 02-12-2015 |
James Horton, Hertfordshire GB
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20110275637 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS - The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias. | 11-10-2011 |
20110275678 | New Pyridine Derivatives as Leptin Receptor Modulator Mimetics - The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias. | 11-10-2011 |
Jeff Horton, Cardiff GB
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20110244487 | METHODS FOR TESTING BINDING OF A LIGAND TO A G PROTEIN-COUPLED RECEPTOR - The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors. | 10-06-2011 |
Jeffrey Horton, Cardiff GB
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20120021440 | METHODS FOR TESTING LIGAND BINDING TO G PROTEIN-COUPLED RECEPTORS - The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors. | 01-26-2012 |
Jeffrey K. Horton, Cardiff GB
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20100311069 | MULTIPLEX CELL SIGNALLING ASSAYS - Disclosed are methods useful in multiplex cell-based assays for compound screening employing imaging instrumentation. The methods described herein offer high content information relating to the biological potency of test agents, off-target effects and cellular toxicity of potential drug candidates. | 12-09-2010 |
20140113294 | DIRECT NUCLEIC ACID AMPLIFICATION KIT, REAGENT AND METHOD - The present invention relates to compositions, methods and kits which can be used to amplify nucleic acids with the advantage of decreasing user time and possible contamination. The dried reagent composition of the invention can be used for easy processing and amplification of nucleic acid samples. | 04-24-2014 |
20140199704 | MULTIPLEX CELL SIGNALLING ASSAYS - Disclosed are methods useful in multiplex cell-based assays for compound screening employing imaging instrumentation. The methods described herein offer high content information relating to the biological potency of test agents, off-target effects and cellular toxicity of potential drug candidates. | 07-17-2014 |
20140212880 | SOLID MEDIUM FOR THE STORAGE OF BIOLOGICAL MATERIAL - This invention relates to flat solid media for the storage of samples of biological materials and methods of analysing biomolecules contained within the samples following storage. In particular, the invention relates to the storage and further analysis of biomolecules present in the biological materials, such as proteins, enzymes and nucleic acids. The invention finds particular utility in the dry, room temperature storage of biological materials. | 07-31-2014 |
Jeffrey Kenneth Horton, Cardiff GB
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20120101005 | METHODS FOR PREDICTING THE TOXICITY OF A CHEMICAL - The invention relates to methods and kits for predicting the effect of a chemical on a developmental pathway. In particular, the invention relates to methods and kits for predicting the toxicity of a chemical on human developmental pathways. The methods and kits of the invention can be used for predicting changes in a cellular biomap or a developmental pathway during human foetal development. | 04-26-2012 |
20120202222 | ENZYME FRAGMENT COMPLEMENTATION ASSAYS FOR MONITORING THE ACTIVATION OF THE VOLTAGE-GATED POTASSIUM ION CHANNEL HERG - The present invention provides methods and cell based assays for testing for the binding of a ligand to a human Ether-a-go-go-related (hERG) voltage-gated potassium ion channel protein in an enzyme complementation assay. The invention is of particular use in toxicological and drug screening, particularly for high throughput screening. | 08-09-2012 |
20120258474 | METHODS OF DETECTING DNA DAMAGE - The present invention relates to methods of detecting agents that cause or may potentiate DNA damage, and to assays that may be employed in such methods. In particular, the invention relates to methods of detecting DNA damage in in vitro cultures of human cells. | 10-11-2012 |
20130045484 | METHODS AND KITS FOR DETERMINING THE TOXICITY OF AN AGENT - The invention relates to methods and kits for determining the toxicity of an agent on a population of eukaryotic cells, particularly human cells. The cells may comprise a nucleic acid construct comprising a DNA damage induced response element operably linked to a sequence encoding a reporter gene. The multiplex methods and kits provide means for distinguishing between genotoxic and cytotoxic agents. | 02-21-2013 |
20130323723 | SOLID SUPPORT AND METHOD OF RECOVERING BIOLOGICAL MATERIAL THEREFROM - The present invention relates to solid supports that are used for the storage and further processing of biological materials. The invention is particularly concerned with solid supports which have at least one surface coated with a chemical mixture that enhances the recovery of the biological material from the support. Methods of preparing and using the solid supports are also described. | 12-05-2013 |
20130323778 | PAPER SUPPORT AND METHOD OF RECOVERING BIOLOGICAL MATERIAL THEREFROM - The present invention relates to paper supports for neonatal screening that are used for the storage and further processing of biological materials. The invention is particularly concerned with paper supports which have at least one surface coated with a chemical that enhances the recovery of the biological material from the support. Methods of preparing and using the paper supports are also described. | 12-05-2013 |
20130330750 | SOLID SUPPORT AND METHOD OF ENHANCING THE RECOVERY OF BIOLOGICAL MATERIAL THEREFROM - The present invention relates to solid supports that are used for the storage and further processing of biological materials. The invention is particularly concerned with solid supports which have at least one surface coated with a chemical that enhances the recovery of the biological material from the support. Methods of preparing and using the solid supports are also described. | 12-12-2013 |
20140154686 | BIOMETRIC DEVICE AND MEANS FOR ELECTRONIC STORAGE AND RETRIEVAL OF BIOMETRIC DATA - There is disclosed a biometric device ( | 06-05-2014 |
John Horton, Southampton GB
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20100076015 | Aminopyridine Derivatives - The present invention provides compounds of formula (I): | 03-25-2010 |
Martin R Horton, Loughborough GB
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20090199746 | Table - A table comprising a frame, a table top surface and a folding leg mechanism, wherein said frame includes a perimeter portion that defines the outside edges of said table, the perimeter portion comprising a plurality of elongate sections joined together by at least one connector, said connector including a first joining part adapted to engage a complimentary part on one of the elongate sections and a second joining part adapted to engage a complimentary part on one of the other elongate sections, said connector also including a mount to connect at least part of the folding leg mechanism to said frame. | 08-13-2009 |
Oliver Trevor Horton, London GB
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20120085870 | VEHICLE ARMREST - An armrest for use by a pilot whilst operating a side stick inceptor has on its underside a number of secondary controls which can be operated when the side stick is not being used, the armrest then acting as a handgrip enabling the pilot to operate the secondary controls with a steady hand. | 04-12-2012 |
Peter Horton, Sheffield GB
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20080318778 | Agriculture Composition Method Comprising Nitric Oxide Generating Agent - The invention discloses the use of a composition comprising at least one nitric oxide generating agent for increasing production of and/or retention of a plant organ. | 12-25-2008 |
Philip Norman Horton, Witney GB
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20100294768 | RESEALABLE BEVERAGE CAN ENDS - A can end combination, a resealable beverage can, and a method of sealing a beverage can are disclosed. The can end combination may include a metal can end and a resealable closure coupled to the can end. The can end may include a center panel having an aperture formed therethrough. The closure may include a base plate and a top plate coupled to the base plate. The closure may have a sealed position in which the base plate contacts the center panel about the aperture to form at least one of a bore seal and a face seal. The closure may also have an intermediate position in which the base plate is proximate the aperture but the closure is devoid of the bore seal and the face seal. The closure may also have a fully open position in which the aperture is exposed to enable pouring liquid through the aperture. | 11-25-2010 |
Richard Horton, Belfast GB
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20110274741 | INGESTIBLE COMPOSITIONS AND PROCESSES OF PREPARATION - One or more of hydrolysed wheat flour, soluble dietary fibre, prebiotic dietary fibre, polydextrose and soluble corn fibre ate used as basic matrix-forming ingredients in an expanded food product. The matrix-forming ingredients are mixed together with water, plus a whey protein isolate or whey protein concentrate, to increase the protein content of the food. A dough is formed which is then formed into pieces which are temperature conditioned before being expanded under a vacuum caused by evaporation of moisture in the dough. All steps of the process of making the expanded food products, including any subsequent drying, is carried out at a temperature not exceeding 75° C., which advantageously allows mixing in of temperature sensitive ingredients, e.g. vitamins, pharmaceuticals, at the dough forming stage. The products have a honeycomb structure and there is no significant change in flavour or nutritional value of the ingredients caused by the process of manufacture. Advantageously, acrylamide formation is also avoided. | 11-10-2011 |
20140167307 | CHEMICAL COMPOSITIONS FOR DELIVERY OF PHARMACEUTICAL AGENTS - One or more of hydrolysed wheat flour, soluble dietary fibre, prebiotic dietary fibre, polydextrose and soluble corn fibre are used as basic matrix-forming ingredients in an expanded food product. The matrix-forming ingredients are mixed together with water, plus a whey protein isolate or whey protein concentrate, to increase the protein content of the food. A dough is formed which is then formed into pieces which are temperature conditioned before being expanded under a vacuum caused by evaporation of moisture in the dough. All steps of the process of making the expanded food products, including any subsequent drying, is carried out at a temperature not exceeding 75° C., which advantageously allows mixing in of temperature sensitive ingredients, e.g. vitamins, pharmaceuticals, at the dough forming stage. The products have a honeycomb structure and there is no significant change in flavour or nutritional value of the ingredients caused by the process of manufacture. Advantageously, acrylamide formation is also avoided. | 06-19-2014 |
Richard Horton, Stourbridge GB
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20090179438 | Rotary Pawl Latch - A latch assembly for releasably securing a first member in a closed position relative to a second member is disclosed. The latch assembly includes a frames a rotary pawl, a locking member, a handle, and a lock plug. The frame is adapted for attachment to the first member. The handle is pivotally attached to the frame and is movable between a closed position and an open position. The locking member retains the pawl in the latched position when the locking member is in an undeflected configuration. The handle causes the locking member to deflect and release the pawl from a latched position when the lacking member is in an unlocked position and the handle is moved to the open position. The lock barrel is supported by the frame and can selectively move the locking member to a locked position where the locking member cannot be actuated by the handle. | 07-16-2009 |
Steuart Horton, Cleveland GB
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20100025939 | Sealing Device and Method of Producing the Same - A sealing device for sealing a first side against a second side of a machine part, wherein the sealing device has a sealing element which contacts a counter element. At least a part of the sealing element and/or at least a part of the counter element is coated with a layer consisting of or containing fullerene-like carbon nitride (FL-CNx), wherein an inter-layer of chromium (Cr) or aluminium (Al) or molybdenum (Mo) or titanium (Ti) or tungsten (W) or a diamond-like coating (DLC) or a metal-mix diamond-like coating (Me-DLC) is arranged between the surface of the sealing element and the layer consisting of or containing fullerene-like carbon nitride and/or between the surface of the counter element and the layer consisting of or containing fullerene-like carbon nitride. | 02-04-2010 |
20100034495 | Bearing and method of producing the same - A bearing comprises at least one inner ring and at least one outer ring. At least a part of the surfaces of the inner ring and/or the outer ring is coated with a layer consisting of or containing fullerene-like carbon nitride (FL-CNx), and wherein an inter-layer of chromium (Cr) or aluminium (Al) or molybdenum (Mo) or titanium (Ti) or tungsten (W) or a diamond-like coating (DLC) or a metal-mix diamond-like coating (Me-DLC) is arranged between the surface of the inner ring and/or the outer ring and the layer. | 02-11-2010 |
20130119615 | SEALING DEVICE AND METHOD OF PRODUCING THE SAME - A sealing device for sealing a first side against a second side of a machine part, wherein the sealing device has a sealing element which contacts a counter element. At least a part of the sealing element and/or at least a part of the counter element is coated with a layer consisting of or containing fullerene-like carbon nitride (FL—CNx), wherein an inter-layer of chromium (Cr) or aluminium (Al) or molybdenum (Mo) or titanium (Ti) or tungsten (W) or a diamond-like coating (DLC) or a metal-mix diamond-like coating (Me-DLC) is arranged between the surface of the sealing element and the layer consisting of or containing fullerene-like carbon nitride and/or between the surface of the counter element and the layer consisting of or containing fullerene-like carbon nitride. | 05-16-2013 |
Thomas J. Horton, Malvern GB
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20100250185 | Method for detection of gravitational anomalies - A method and system for detecting gravitational anomalies comprises measuring surface structures, measuring gravitational field characteristics, and estimating the effect of the surface structures on the gravitational measurements. The estimations are then used to derive a representation of nearby non visible features such as changes in rock density, voids, or oil and gas deposits. The surface structures may be measured by a video camera, with the video sequence being processed to estimate 3D positions of structures relative to the measurement point. Other methods may be used, such as lidar or acoustic techniques as appropriate. The method may be applied above ground and also has efficacy in borehole and sewer surveying applications. | 09-30-2010 |
Thomas John Horton, Worcestershire GB
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20120032675 | Apparatus and Method for Ferromagnetic Object Detector - An apparatus is provided for compensating for the effect of a stray ferromagnetic object moving past but not through a sensing region of a ferromagnetic object detector. The ferromagnetic object detector is of a type to produce a plurality of sensor signals, each sensor signal being influenced by the presence of a genuine ferromagnetic object moving through the sensing region but also liable to be influenced by the presence of the stray object. The apparatus comprises: an input for receiving the plurality of sensor signals and first means for analysing the received signals to determine whether there is a substantially same time-varying component present in each of the signals. The apparatus also comprises second means for determining whether the plurality of signals without the contribution of that time-varying component are each or collectively below a predetermined level of significance. The apparatus also comprises third means for indicating, if the respective determinations from the first and second means are both positive, that the received signals are likely to relate to a stray object and not to a genuine ferromagnetic object moving through the sensing region. | 02-09-2012 |
20120074943 | Apparatus and Method for Ferromagnetic Object Detector - An apparatus is provided for compensating for the effect of a moving door on a nearby ferromagnetic object detector. The ferromagnetic object detector is of a type to produce a main sensor signal indicative of the presence of a ferromagnetic object in the vicinity of the ferromagnetic object detector. Furthermore, the door is arranged relative to the ferromagnetic object detector such that movement of the door is liable to introduce an undesirable interference signal into the main sensor signal. The apparatus comprises an input ( | 03-29-2012 |
Thomas John Horton, Malvern GB
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20130311130 | PROXIMITY SENSOR SYSTEM - A sensor system includes a sensor and processing means adapted to process the signals from the sensor, and to provide a distance measurement or estimate from the sensor to a metallic object of interest, such as a turbine blade. The sensor, typically an eddy current sensor, provides a signal to which the processing means fits a curve, and parameters including pulse width and height are taken from the fitted curve and used in calculating the distance measurement or estimate. Look-up tables may be used to produce the measurement or estimate. Average values of the parameters may calculated to reduce random noise effects and may be subsequently used to produce correction factors to correct instantaneous measurements. | 11-21-2013 |