Patent application number | Description | Published |
20090266915 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 10-29-2009 |
20090266916 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 10-29-2009 |
20100147883 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 06-17-2010 |
20100170964 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 07-08-2010 |
20110284664 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 11-24-2011 |
20110284665 | Spraying device apparatus - A spraying device includes a housing that has a spraying unit and a trigger assembly. The spraying unit is a removable insert within the housing. The spraying unit includes an air chamber that is coupled to a liquid tank. A front end portion of the air chamber has a nozzle. The air chamber receives a liquid tube that opens in the nozzle. The liquid tube receives a needle and the needle and the liquid tube are coaxial with each other. The trigger assembly controls the flow of liquid through the liquid tube by positioning a tapered front end of the needle. The trigger assembly includes a trigger that has a first position and a second position. In the first position, the opening of the liquid tube is closed by the needle. In a second position, the liquid tube is opened to discharge a liquid from an opening of the liquid tube. | 11-24-2011 |
20120042753 | ELECTRIC CAN OPENER AND METHOD OF OPENING A CAN - To solve problems in a conventional electric can opening apparatus wherein it is impractical to drain the unwanted liquid from the inside of the can after opening the container and disposing of the top lid or top without touching it. The composite can opener includes a body with a gripping member gripping a can while an opening member cuts the top of the can open and a piston that selectively pushes the top into and out of the can after it has been cut. | 02-23-2012 |
20130133211 | ELECTRIC CAN OPENER AND METHOD OF OPENING A CAN - To solve problems in a conventional electric can opening apparatus wherein it is impractical to drain the unwanted liquid from the inside of the can after opening the container and disposing of the top lid or top without touching it. The composite can opener includes a body with a gripping member gripping a can while an opening member cuts the top of the can open and a piston that selectively pushes the top into and out of the can after it has been cut. | 05-30-2013 |
20140252127 | Multi-color spraying device - A spraying device with multi-color cartridge, having an array of liquid tanks, arranged around horizontal axel of cartridge rotation. | 09-11-2014 |
20150014434 | ULTRASONIC SPRAYING DEVICE / AIR-ASSISTED ULTRASONIC SPRAYING DEVICE WITH ADVANCING CARTRIDGE PISTON - The invention provides systems and methods for delivering a fluid, which may be a cosmetic fluid. The fluid delivery system may employ ultrasonic energy to deliver fluid contained in a cartridge using a spraying device. The fluid delivery system may be modular. | 01-15-2015 |
20150250288 | SPRAYING DEVICE APPARATUS - A unit for spraying including a spraying unit adapted to be removably coupled to a spraying handle. The spraying unit comprising a media tank, an air chamber, a nozzle with a needle and an air intake. The unit for spraying capable of spraying media. | 09-10-2015 |
Patent application number | Description | Published |
20090048290 | 2S,3R)-N-(2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL-BENZYOFURAN-- 2-CARBOXAMIDE, NOVEL SALT FORMS, AND METHODS OF USE THEREOF - The present invention relates to (2S,3R)—N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms thereof, methods for its preparation, novel intermediates, and methods for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central and autonomic nervous systems. | 02-19-2009 |
20110257168 | DERIVATIVES OF OXABISPIDINE AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS - The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 10-20-2011 |
20110257224 | PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S,3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUO- ROBENZAMIDE - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetyl-choline receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 10-20-2011 |
20120015983 | Synthesis and Novel Salt Forms of (R)-3-((E)-pyrrolidin-3-yl)vinyl)-5-tetrahydropyran-4-yloxy)pyridine - The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions. | 01-19-2012 |
20140107163 | SYNTHESIS AND NOVEL SALT FORMS OF (R)-3-((E)-2-(PYRROLIDIN-3-YL)VINYL)-5-(TETRAHYDROPYRAN-4-YLOXY)PYRIDINE - The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions. | 04-17-2014 |
20140163065 | PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S, 3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUOROBE- NZAMIDE - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 06-12-2014 |
Patent application number | Description | Published |
20140114138 | RETRACTOR DEVICE AND METHOD - The present disclosure generally relates to a retractor device for retracting soft tissue to provide access to a surgical site. The retractor device includes a plurality of blades movable from a first, substantially closed position to a second, substantially open position. Related methods of using the retractor device are also described. | 04-24-2014 |
20140114139 | RETRACTOR DEVICE AND METHOD - The present disclosure generally relates to a retractor device for retracting soft tissue to provide access to a surgical site. The retractor device includes a plurality of arms coupled to a frame and operatively coupled to a ring disposed at least partially within the frame. Related methods of using the retractor device are also described. | 04-24-2014 |
20140135839 | PERCUTANEOUS MODULAR HEAD-TO-HEAD CROSS CONNECTOR - A modular head-to-head cross connector or construct extension system comprising a fastener element driven into a bone in a first orientation, a first U-shaped body operable to receive the fastener element and operable to receive a first rod in a first rod receiving channel, and a first compression element driven adjacent to and against the first rod in the first rod receiving channel, thereby engaging the first rod against the fastener element in a second orientation independent of the first orientation of the fastener element. The system further comprises a second U-shaped body operable to receive first compression element and operable to receive a second rod in a second rod receiving channel, and a second compression element driven adjacent to and against the second rod in the second rod receiving channel, thereby engaging the second rod against the first compression element in a third orientation independent of the second orientation. | 05-15-2014 |
20150230830 | PERCUTANEOUS MODULAR HEAD-TO-HEAD CROSS CONNECTOR - A modular head-to-head cross connector or construct extension system comprising a fastener element driven into a bone in a first orientation, a first U-shaped body operable to receive the fastener element and operable to receive a first rod in a first rod receiving channel, and a first compression element driven adjacent to and against the first rod in the first rod receiving channel, thereby engaging the first rod against the fastener element in a second orientation independent of the first orientation of the fastener element. The system further comprises a second U-shaped body operable to receive first compression element and operable to receive a second rod in a second rod receiving channel, and a second compression element driven adjacent to and against the second rod in the second rod receiving channel, thereby engaging the second rod against the first compression element in a third orientation independent of the second orientation. | 08-20-2015 |
Patent application number | Description | Published |
20100022049 | Mid-IR Microchip Laser: ZnS:Cr2+ Laser with Saturable Absorber Material - A method of fabrication of laser gain material and utilization of such media includes the steps of introducing a transitional metal, preferably Cr | 01-28-2010 |
20100246610 | Mid-IR Laser Instrument for Analyzing a Gaseous Sample and Method for Using the Same - An optical nose for detecting the presence of molecular contaminants in gaseous samples utilizes a tunable seed laser output in conjunction with a pulsed reference laser output to generate a mid-range IR laser output in the 2 to 20 micrometer range for use as a discriminating light source in a photo-acoustic gas analyzer. | 09-30-2010 |
20120224599 | MID-IR MICROCHIP LASER: ZNS:CR2+ LASER WITH SATURABLE ABSORBER MATERIAL - A method of fabrication of laser gain material and utilization of such media includes the steps of introducing a transitional metal, preferably Cr | 09-06-2012 |
20140321494 | MIDDLE-INFRARED VOLUMETRIC BRAGG GRATING BASED ON ALKALI HALIDE OR ALKILI-EARTH FLOURIDE COLOR CENTER CRYSTALS - Volumetric Bragg grating devices that operate in middle-infrared region of the spectrum and methods for producing such devices are described. Such a Volumetric Bragg grating device can be produced by forming a plurality of color centers within an alkali-halide or an alkali-earth fluoride crystal and selectively removing a subset of the plurality of color centers to produce variations in refractive index of the alkali-halide or alkali-earth fluoride crystal in the middle-infrared spectral region and to thereby produce a volumetric Bragg grating that operates in middle-infrared spectral range. | 10-30-2014 |
20140348200 | MIDDLE-INFRARED VOLUMETRIC BRAGG GRATING BASED ON ALKALI HALIDE COLOR CENTER CRYSTALS - Volumetric Bragg grating devices that operate in middle-infrared region of the spectrum and methods for producing such devices are described. Such a Volumetric Bragg grating device can be produced by forming a plurality of color centers within an alkali-halide crystal and selectively removing a subset of the plurality of color centers to produce variations in refractive index of the alkali-halide crystal in the middle-infrared spectral region and to thereby produce a volumetric Bragg grating that operates in middle-infrared spectral range. | 11-27-2014 |
20140362879 | SATURABLE ABSORBERS FOR Q-SWITCHING OF MIDDLE INFRARED LASER CAVATIES - This disclosure demonstrates successfully using single, polycrystalline, hot pressed ceramic, and thin film Fe doped binary chalcogenides (such as ZnSe and ZnS) as saturable absorbing passive Q-switches. The method of producing polycrystalline ZnSe(S) yields fairly uniform distribution of dopant, large coefficients of absorption (5-50 cm | 12-11-2014 |
20150333470 | MID-IR MICROCHIP LASER: ZNS:CR2+ LASER WITH SATURABLE ABSORBER MATERIAL - A method of fabrication of laser gain material and utilization of such media includes the steps of introducing a transitional metal, preferably Cr | 11-19-2015 |
Patent application number | Description | Published |
20090280567 | STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS - RNA molecules, including siRNA molecules and related control, trackability and exaequo agents with specific stability modifications are provided. These molecules are particularly advantageous as transfection control reagents. The molecules include first and second 5′ terminal sense nucleotides with 2′-O-alkyl groups and a label on the first 5′ terminal sense nucleotide, in conjunction with at least one additional 2′-O-alkyl pyrimidine modified sense nucleotide, and either: (i) at least one 2′ fluoro modified pyrimidine antisense nucleotide and a phosphorylated first 5′ terminal antisense nucleotide; or (ii) a first and second 5′ terminal antisense nucleotide with 2′-O-alkyl modifications and at least one additional 2′-O-alkyl pyrimidine modified antisense nucleotide. | 11-12-2009 |
20100173359 | ENHANCED BIOTHERAPEUTIC PRODUCTION USING INHIBITORY RNA - Compositions, kits, systems, equipment, and protocols utilize synthetic siRNA having a delivery facilitating moiety in improved bioprocesses that enhance the production of biomaterials. The siRNA can target genes associated with the following: 1) deleterious vector derived genes; 2) genes that confer non-optimal growth or differentiation properties to the cells; 3) genes that can influence heterogeneity or post-translational modification pattern of the desirable gene product; 4) genes that highly express non-desired proteins; 5) genes that express proteins which interfere with purification of the desired protein; and 6) other genes that can interfere with the bioprocess. | 07-08-2010 |
20100184209 | COMPOSITIONS AND METHODS FOR INHIBITING GENE SILENCING BY RNA INTERFERENCE - The present invention provides compositions and methods for inhibiting gene silencing by the RNAi pathway. The RNAi inhibitors of the invention have a reverse complement (RC) region to the target molecule of interest (e.g., miRNA) in association with at least one flanking region coupled to either at the 3′ or 5′ end of the RC region. The flanking regions can be single-stranded or can have one or more regions of double stranded nucleic acid with or without a hairpin loop. The RNAi inhibitors described herein can inhibit endogenous targets, including but not limited to microRNAs, or piRNAs, or can be used to inhibit the effects of exogenously introduced molecules, such as synthetic siRNAs, siRNAs expressed from vector constructs (e.g., viral expression systems), or siRNAs generated by enzymatic methods. Inhibition is specific, potent, prolonged, and can be performed on a single target or multiple targets simultaneously. | 07-22-2010 |
20100197023 | MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE - Methods and compositions for performing RNA interference comprising a wide variety of stabilized siRNAs suitable for use in serum-containing media and for in vivo applications, such as therapeutic applications, are provided. These siRNAs permit effective and efficient applications of RNA interference to applications such as diagnostics and therapeutics through the use of one or more modifications including orthoesters, terminal conjugates, modified linkages and 2′ modified nucleotides. Uniquely modified siRNAs have been developed that reduces off-target effects incurred in gene-silencing. The modifications include phosphorylation of the first 5′ terminal antisense nucleotide; 2′ carbon modifications of the first and second or first, second, and third 5′ terminal antisense nucleotides; and optionally 2′ carbon modifications of the first and second or first, second, and third 5′ terminal sense nucleotide. Control and exaequo molecules are also provided. siRNA molecules and related control, trackability and exaequo agents with specific stability modifications were developed. | 08-05-2010 |