Patent application number | Description | Published |
20100042093 | System and method for terminating treatment in impedance feedback algorithm - A system and method for performing electrosurgical procedures are disclosed. The system includes an electrosurgical generator adapted to supply energy at an output level to tissue. The electrosurgical generator includes a microprocessor adapted to generate a desired impedance trajectory having at least one slope. The target impedance trajectory includes one or more target impedance values. The microprocessor is also adapted to drive tissue impedance along the target impedance trajectory by adjusting the output level to substantially match tissue impedance to a corresponding target impedance value. The microprocessor is further adapted to compare tissue impedance to a threshold impedance value and adjust output of the electrosurgical generator when the tissue impedance is equal to or greater than the threshold impedance. The system also includes an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue. | 02-18-2010 |
20100217264 | System and Method for Controlling RF Output During Tissue Sealing - An electrosurgical system for sealing tissue is disclosed. The system includes a forceps having opposing jaw members that cooperate to grasp tissue therebetween, wherein each of the jaw members includes a sealing plate that is connected to an electrosurgical generator and is configured to communicate electro surgical energy through the tissue held therebetween. The system also includes at least one sensor which determines a gap distance between the sealing plates of the jaw members and a microprocessor programmed to communicate with the at least one sensor to measure an initial gap distance between the sealing plates and to generate at least one desired gap distance value based on the initial gap distance, the microprocessor further programmed to communicate with the at least one sensor to adjust output level of the electrosurgical generator as a function of the measured gap distance during the sealing process. | 08-26-2010 |
20100225478 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 09-09-2010 |
20110132073 | Fatigue Testing System for Prosthetic Devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 06-09-2011 |
20110146385 | Fatigue evaluation of prostheses by radial excitation of tubular structures - Prostheses are fatigue tested using an apparatus under simulated physiological loading conditions. A fluid housing defines an entrance chamber having fluid outflow ports and an exit chamber having opposing fluid inflow ports and a central flow conduit in communication with the entrance chamber and the exit chamber. A plurality of housing tubes into which prosthesis are deployed may extend between the fluid outflow and inflow ports. Alternatively, tubular prostheses may be connected directly between the inflow and outflow ports. A reciprocating linear drive pump having a flexible diaphragm is provided to cyclically pressurize fluid through a common closed loop within the fluid housing and drive the pressurized fluid through the prosthesis being tested. The test system is capable of rotation independent of the motor drive for accurate diameter measurements of all test samples at elevated frequencies. | 06-23-2011 |
20110178519 | Vessel Sealing Instrument with Electrical Cutting Mechanism - An end effector assembly for use with an instrument for sealing vessels and cutting vessels includes a pair of opposing first and second jaw members which are movable relative to one another from a first spaced apart position to a second position for grasping tissue therebetween. Each jaw member includes an electrically conductive tissue contacting surface connected to an electrosurgical energy source. At least one of the jaw members includes an electrically conductive cutting element disposed within an insulator defined in the jaw member. At least one channel is included in the insulator which is configured to deliver fluid between the jaw members. | 07-21-2011 |
20120022521 | System And Method For Measuring Initial Tissue Impedance - An electrosurgical system and method are disclosed. The system includes an electrosurgical generator adapted to supply electrosurgical energy to tissue. The generator is further adapted to supply an electrical signal having at least one substantially constant value to tissue to determine initial tissue impedance response. The generator includes sensor circuitry adapted to continuously monitor initial tissue impedance response, wherein the initial tissue impedance response includes one of an initial impedance, an impedance drop, an impedance minimum and a first impedance rise. The generator also includes a microprocessor adapted to generate at least one tissue parameter based as a function of the initial impedance, the impedance drop, the impedance minimum and the first impedance rise. The system also includes an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue for treatment. | 01-26-2012 |
20120233844 | VESSEL SEALING INSTRUMENT WITH ELECTRICAL CUTTING MECHANISM - An end effector assembly for use with an instrument for sealing vessels and cutting vessels includes a pair of opposing first and second jaw members which are movable relative to one another from a first spaced apart position to a second position for grasping tissue therebetween. Each jaw member includes an electrically conductive tissue contacting surface connected to an electrosurgical energy source. At least one of the jaw members includes an electrically conductive cutting element disposed within an insulator defined in the jaw member. A rigid structural support is included which is configured to support the electrically conductive tissue sealing surface and includes at least one flow channel defined therein. | 09-20-2012 |
20130233397 | Regurgitant Control Directional Flow Valve for Simulating Cardiovascular Hemodynamics - A directional flow valve in a cardiovascular prosthesis test system includes a regurgitant flow passage. Forward flow from a pump through the valve is unrestricted and allowed to pass freely through the directional flow valve. Regurgitant flow is allowed across the directional flow valve to reduce a negative pressure gradient across the prosthetic device. The volume of regurgitant flow is controllable by changing a size of the regurgitant flow pathway. | 09-12-2013 |
20140109651 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 04-24-2014 |
20140180275 | METHOD AND SYSTEM FOR CONTROLLING AN OUTPUT OF A RADIO-FREQUENCY MEDICAL GENERATOR HAVING AN IMPEDANCE BASED CONTROL ALGORITHM - A system for performing an electrosurgical procedure at a surgical site is disclosed. The system includes a sensor configured to continually sense an electrical and/or a physical property of tissue at a surgical site and to generate a sensor signal as a function thereof. The system also includes a control module configured to process the sensor signal using a processor, an algorithm, and a map having one or more predetermined values. The control module is further configured to compare the sensor signal to a predetermined level to determine reliability of the sensor signal and to signal an electrosurgical generator in response to a reliable sensor signal such that the electrosurgical generator enters energy control mode, wherein the electrosurgical generator matches an output of the control signal with a predetermined value from the map. | 06-26-2014 |
20150040644 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 02-12-2015 |
Patent application number | Description | Published |
20120092105 | FLEXIBLE METHODS OF FABRICATING ELECTROMAGNETS AND RESULTING ELECTROMAGNET ELEMENTS - An electromagnetic structure is fabricated by additive manufacturing having at least one channel traversing the structure. In one embodiment, at least one form contains apertures and/or holes forming the channel and a liquid metal traverses the structure by the channel. Electrodes are provided to apply or extract electrical voltage or power to and/or from the liquid metal as well as a mechanism for propelling a portion of the liquid metal through the form. In an alternative embodiment, both the electrically insulating and the electrically conductive materials are solid and the channel is used for conducting a coolant instead of the liquid metal. | 04-19-2012 |
20120116148 | MAGNETIC-ASSISTED TUMOR CONFINEMENT METHODOLOGY AND EQUIPMENT - Disclosed embodiments are directed to reducing the likelihood of intra-operative shedding. Specifically, disclosed embodiments utilize injected magnetic nanoparticles and magnets to confine tumor cells to the surgical bed in order to prevent the cells from being released into the general circulation and/or lymphatics. | 05-10-2012 |
20120175584 | STRUCTURES FOR RADIATION DETECTION AND ENERGY CONVERSION USING QUANTUM DOTS - Inorganic semiconducting materials such as silicon are used as a host matrix in which quantum dots reside to provide a radiation detector or energy converter. The quantum dot material may be disposed by incorporating materials sensitive to neutron detection such as boron-containing compounds, or the use of methods such as chemical vapor deposition or atomic layer deposition to insert the quantum dot material. Electrodes may be extended deep into the host matrix material to improve efficiency. Likewise, the host matrix may be machined to create pores in the matrix material. Further, amplification and signal-processing structures may be used in close proximity to the radiation-sensitive region of the device. | 07-12-2012 |
20120261639 | STRUCTURES FOR RADIATION DETECTION AND ENERGY CONVERSION USING QUANTUM DOTS - Inorganic semiconducting materials such as silicon are used as a host matrix in which quantum dots reside to provide an energy conversion device that may be used to convert various types of radiation to electricity. | 10-18-2012 |
20120326722 | ULTRA-FAST MAGNETIC FIELD FOR ELECTRON PARAMAGNETIC RESONANCE IMAGING USED IN MONITORING DOSE FROM PROTON OR HADRON THERAPY - Instrumentation and methodologies are provided that enable the direct measurement of free radicals generated in patients as a result of radiation therapy through the use of proton beams and other forms of ionizing radiation. As a result, in accordance with at least one disclosed embodiment, the instrumentation and methodologies may be used in conjunction with radiation therapy to detect, monitor and/or control generation of free radicals in cancerous tissue during such radiation therapy. | 12-27-2012 |
20130015856 | MRI MICROSCOPE ADAPTER - Disclosed embodiments pertain to an inventive method and apparatus that confers the ability to image using Magnetic Resonance Imaging (MRI) to an optical microscope. Through implementation of the disclosed embodiments, it is possible to collect spectroscopic information as well as anatomic information using the objective structure and/or MRI-enabled stage. | 01-17-2013 |
20130046169 | MRI-GUIDED NANOPARTICLE CANCER THERAPY APPARATUS AND METHODOLOGY - An apparatus and method direct nanoparticles in a body part under imaging guidance using at least one electromagnet configured and operable to create a magnetic field gradient used to direct the nanoparticles, wherein, the magnetic field gradient used to direct the nanoparticles does not substantially interfere with the use of magnetic field gradients whose purpose is to image the body part. | 02-21-2013 |
20130046288 | METHOD AND APPARATUS FOR REMOVING NOXIOUS MATERIALS FROM CELLS - A method and apparatus are provided for removing noxious or unneeded materials from cells in a subject's body. | 02-21-2013 |
20130146458 | RAPID COMPACT ASSAY FOR PARENT RADIONUCLIDES IN GENERATORS - Disclosed embodiments assay for the presence of Ge-68, although disclosed embodiments can also be used for other radionuclide generators, with minimal adjustments. | 06-13-2013 |
20130204120 | EQUIPMENT AND METHODOLOGIES FOR MAGNETICALLY-ASSISTED DELIVERY OF THERAPEUTIC AGENTS THROUGH BARRIERS - Magnetic gradients are used to transport Magnetic Nano Particles through a barrier, for example, the cribiform (also spelled “cribriform”) plate, which is a porous bony structure which separates the nasal cavity from the cranial vault. By utilizing a configuration of magnets (whether of the electromagnetic type or permanent magnets), MNPs can be propelled, pushed, pulled or otherwise manipulated in relation to an anatomical and/or physiological barrier, to position, re-position or maintain the position(s) of the MNPs. | 08-08-2013 |
20130218010 | PORTABLE PET SCANNER FOR IMAGING THE HUMAN BRAIN - In accordance with at least one disclosed embodiment, an apparatus for use in imaging the human brain by describing the distribution of radiotracers in the human brain is provided. The apparatus may be compact and lightweight enough to be lifted by hand (less than 50 pounds) and affixed to a patient bed. In addition, the apparatus may collect images of both the cerebrum and cerebellum of the patient. | 08-22-2013 |
20130257428 | METHOD AND APPARATUS FOR HIGH RESOLUTION PHYSIOLOGICAL IMAGING OF NEURONS - In accordance with disclosed embodiments, very high magnetic gradients and magnetic slew are applied to magnetizable particle imaging in order to realize high spatial resolution. | 10-03-2013 |
20130271136 | APPARATUS AND METHOD FOR DECREASING BIO-EFFECTS OF MAGNETIC GRADIENT FIELD GRADIENTS - A magnetic field generator includes a power source and a segmented or un-segmented coil connected to the power source to generate a time-varying magnetic field. Energy is applied to the coil so that the coil generates a time-varying magnetic field gradient with a magnitude of at least 1 milliTesla per meter and a rise-time of less than 1000 microseconds. The coil may be comprised of overlapping, non-overlapping or partially overlapping coil segments that may individually energized to further improve the operating characteristics of the coil to further decrease bio-effects in magnetic resonance imaging through the use of reduced pulse lengths and multi-phasic magnetic gradient pulses. | 10-17-2013 |
20130296631 | CLEANING ARTERIOSCLEROTIC VESSELS WITH MAGNETIC NANOSWIMMERS - Disclosed embodiments provide an apparatus and method for brushing plaques from vessels by exposing intraluminal nanoparticles to changing magnetic gradients. | 11-07-2013 |
20140206927 | APPARATUS AND METHOD FOR SPATIALLY SELECTIVE INTERVENTIONAL NEUROPARTICLES - An apparatus and method are provided for spatially-selective administration of actions by at least one device in the body using a transducer that is sensitive to a spatially-variant energy field imposed on the at least one device by a source external to a subject's body; and at least one component in the at least one device, wherein interaction of the transducer with the imposed spatially-variant energy field causes or enables at least one component in the at least one device to affect nearby tissues in the body. | 07-24-2014 |
20140309479 | SYSTEM, METHOD AND EQUIPMENT FOR IMPLEMENTING TEMPORARY DIAMAGNETIC PROPULSIVE FOCUSING EFFECT WITH TRANSIENT APPLIED MAGNETIC FIELD PULSES - An apparatus and method are utilized to transiently implement diamagnetic behavior in both permanently and transiently magnetized particles. | 10-16-2014 |
20140375315 | ENERGY-SAVING METHOD OF GENERATING TIME-VARYING MAGNETIC GRADIENTS FOR USE IN MRI - An apparatus and method which produce a magnetic field gradient by physically rotating one or more permanent magnets near an object in order to obtain images of the object. | 12-25-2014 |
20140378824 | POINT-OF-CARE NON-INVASIVE ASSAY OF LITHIUM LEVEL - An apparatus and method perform non-invasive lithium measurement of a patient wherein an apparatus comprising a permanent magnet, and at least one radiofrequency coil tuned to the resonant frequency of one or more isotopes of lithium are coupled to a cavity less than 5 cm in diameter in which a subject's body part (other than the subject's brain) can be inserted, wherein, the concentration of lithium in the subject's body is assessed based on one or more measurements of an amount of lithium detected in the body part without the need for withdrawing fluids from the body. | 12-25-2014 |
20150145624 | ELECTROMAGNETIC MOTOR AND OTHER ELECTROMAGNETIC DEVICES WITH INTEGRATED COOLING - An apparatus, and method of constructing such an apparatus, conducts and insulates materials with intervening coolant channels, wherein the conducting materials form an electromagnet. | 05-28-2015 |
20150160312 | RF LENSES FOR SINGLE-SIDED MAGNETIC IMAGING APPLICATIONS - An apparatus and method perform imaging at a distance that is not immediately adjacent from the face of a single-sided magnetic imaging instrument held adjacent to a sample, where the volume of interest is not adjacent to the magnetic imaging instrument. | 06-11-2015 |
20150238110 | NEUROPARTICLE WITH A SPIN-TORQUE DEVICE - Disclosed embodiments enable determining and monitoring the location of at least one particle in a subject's body, as well as the status of a local environment within the body where the at least one particle is located. | 08-27-2015 |
20160095532 | METHOD AND COMPONENTS FOR IN VIVO DETERMINATION OF MALIGNANCY - An apparatus and method apply magnetic fields by generators external to a body or body part with sensors within an in vivo source that are sensitive to applied magnetic fields Through the use of these applied magnetic fields and sensitive sensors, disclosed embodiments can realize much better spatial resolution than is conventionally possible. | 04-07-2016 |
20160096030 | PULSED GRADIENT FIELD METHOD TO COUNTERACT A STATIC MAGNETIC FIELD FOR MAGNETIC PARTICLE FOCUSING - Disclosed embodiments provide an apparatus and method that produce a magnetic field gradient configured to counteract effects of a static magnetic field such that the combination of the two fields may be applied to one or more magnetic particles to manipulate the magnetic particle(s). | 04-07-2016 |
20160096031 | METHOD AND APPARATUS FOR IMAGE-DIRECTED NERVE GROWTH - Disclosed embodiments are directed to promoting nerve growth through one or more mechanisms using an apparatus to rapidly change magnetic fields. | 04-07-2016 |
Patent application number | Description | Published |
20090136496 | CHRONIC LYMPHOCYTIC LEUKEMIA PROGNOSIS AND TREATMENT - Provided herein are methods for identifying a subject afflicted with chronic lymphocytic leukemia who is responsive to treatment with a chemotherapeutic agent by detecting the presence or absence of at least one APOE4 allele in the subject, the presence of an APOE4 allele identifying the subject as responsive to the treatment. Also provided are methods of treating a subject afflicted with chronic lymphocytic leukemia, including administering an estrogenic agent, an androgen withdrawal agent, an apoE4 peptide or mimetic thereof, and/or a chemotherapeutic agent in an amount effective to treat said chronic lymphocytic leukemia. Methods of determining a prognosis for a patient diagnosed with chronic lymphocytic leukemia are also provided. In addition, methods for stratifying a subject into a subgroup of a clinical trial and methods for identifying a patient in a clinical trial of a treatment for chronic lymphocytic leukemia are herein provided. | 05-28-2009 |
20110189175 | CHRONIC LYMPHOCYTIC LEUKEMIA PROGNOSIS AND TREATMENT - Provided herein are methods for identifying a subject afflicted with chronic lymphocytic leukemia who is responsive to treatment with a chemotherapeutic agent by detecting the presence or absence of at least one APOE4 allele in the subject, the presence of an APOE4 allele identifying the subject as responsive to the treatment. Also provided are methods of treating a subject afflicted with chronic lymphocytic leukemia, including administering an estrogenic agent, an androgen withdrawal agent, an apoE4 peptide or mimetic thereof, and/or a chemotherapeutic agent in an amount effective to treat said chronic lymphocytic leukemia. Methods of determining a prognosis for a patient diagnosed with chronic lymphocytic leukemia are also provided. In addition, methods for stratifying a subject into a subgroup of a clinical trial and methods for identifying a patient in a clinical trial of a treatment for chronic lymphocytic leukemia are herein provided. | 08-04-2011 |
20110319360 | Method of including apoptosis/Cell death in leukemia cell using a purine nucleoside analogue - A method of inducing apoptosis or cell death in a leukemia cell includes subjecting the cell to a purine nucleotide analogue, LMP-420 (2-amino-6-chloro-9-[5(dihydroxyboryl)-pentyl] purine). | 12-29-2011 |
20130018001 | METHODS OF DIAGNOSING CANCER - Provided are methods of predicting or assessing the level of severity of cancer or cancer progression in a patient comprising measuring levels of SET expression in a biological sample from a patient and comparing levels of SET expression to a control sample or standard value. Methods for predicting or evaluating the efficacy of a SET therapeutic and kits comprising at least one reagent for measuring SET protein expression are also provided. | 01-17-2013 |
20150150941 | CHRONIC LYMPHOCYTIC LEUKEMIA PROGNOSIS AND TREATMENT - Provided herein are methods for identifying a subject afflicted with chronic lymphocytic leukemia who is responsive to treatment with a chemotherapeutic agent by detecting the presence or absence of at least one APOE4 allele in the subject, the presence of an APOE4 allele identifying the subject as responsive to the treatment. Also provided are methods of treating a subject afflicted with chronic lymphocytic leukemia, including administering an estrogenic agent, an androgen withdrawal agent, an apoE4 peptide or mimetic thereof, and/or a chemotherapeutic agent in an amount effective to treat said chronic lymphocytic leukemia. Methods of determining a prognosis for a patient diagnosed with chronic lymphocytic leukemia are also provided. In addition, methods for stratifying a subject into a subgroup of a clinical trial and methods for identifying a patient in a clinical trial of a treatment for chronic lymphocytic leukemia are herein provided. | 06-04-2015 |
Patent application number | Description | Published |
20090038213 | PRE-BURNING, DRY PROCESS METHODOLOGY AND SYSTEMS FOR ENHANCING METALLURGICAL SOLID FUEL PROPERTIES - Measurements are taken of moisture, BTU/lb (British Thermal Units per pound), ash, forms of sulfur, volatile material, grindability, and absorption properties of any of a wide variety of mine-run solid fuels. Using that information, a dry electromagnetic process technology has been developed that can be controlled and monitored to selectively alter and enhance metallurgical solid fuel properties. Specific changes include altering the mechanical structure and chemical composition of solid fuels such as coal, coal coke or petroleum coke, increasing the BTU/lb to optimum levels, decreasing all forms of sulfur, and decreasing ash, while maintaining the BTU/lb of the fuels. A new family of solid fuel designer coals not found in nature can be produced via these methods and apparatus. | 02-12-2009 |
20140070116 | PRE-BURNING, DRY PROCESS METHODOLOGY AND SYSTEMS FOR ENHANCING METTALLURGICAL SOLID FUEL PROPERTIES - Measurements are taken of moisture, BTU/lb (British Thermal Units per pound), ash, forms of sulfur, volatile material, grindability, and absorption properties of any of a wide variety of mine-run solid fuels. Using that information, a dry electromagnetic process technology has been developed that can be controlled and monitored to selectively alter and enhance metallurgical solid fuel properties. Specific changes include altering the mechanical structure and chemical composition of solid fuels such as coal, coal coke or petroleum coke, increasing the BTU/lb to optimum levels, decreasing all forms of sulfur, and decreasing ash, while maintaining the BTU/lb of the fuels. A new family of solid fuel designer coals not found in nature can be produced via these methods and apparatus. | 03-13-2014 |
Patent application number | Description | Published |
20110282893 | DECREASING DUPLICATES AND LOOPS IN AN ACTIVITY RECORD - The claimed subject matter provides a system and/or a method for decreasing duplicate entries and loops in an activity record such as on a user's page on a social networking site. An exemplary method comprises analyzing a new entry from a user to determine an originating service and a type of activity and extracting an identifying portion of the new entry. The identifying portion is compared to a list of prior entries from the user, and an exclusion action is performed, if the new entry matches one in the list of prior entries. The exclusion action may be to hide the new entry, to delete the new entry, or to collapse the new entry into a matching prior entry. | 11-17-2011 |
20110314064 | Notifications Platform - Described is a notifications platform that routes notifications to endpoints of recipients, corresponding to email, instant messaging, text messaging, telephones, social networks, blogs and/or the like. A publisher of a notification designates the recipients, while preference data of each recipient determines whether that publisher is able to send to that recipient, and if so, to which endpoints. The notification may be modified via one or more templates to be appropriate for a locale of the recipient, as well as appropriately formatted for the endpoint, which may also be locale-specific. | 12-22-2011 |
20150058303 | DECREASING DUPLICATES AND LOOPS IN AN ACTIVITY RECORD - The claimed subject matter decreases duplicate entries and loops in an activity record. An exemplary method comprises analyzing a new entry from a user to determine an originating service and a type of activity and extracting an identifying portion of the new entry. The identifying portion includes a predetermined number of characters at a beginning of the entry. Additionally, the predetermined number of characters is based on a likelihood of duplicates in the activity record. The identifying portion is compared to a list of prior entries from the user, and an exclusion action is performed, if the new entry matches one in the list of prior entries. The exclusion action may be to hide the new entry, to delete the new entry, or to collapse the new entry into a matching prior entry. | 02-26-2015 |
Patent application number | Description | Published |
20080311043 | Uses and compositions for treatment of psoriatic arthritis - The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriatic arthritis in a subject. | 12-18-2008 |
20140234222 | USE OF TNF ALPHA INHIBITOR FOR TREATMENT OF EROSIVE POLYARTHRITIS - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 08-21-2014 |
20140248215 | USES AND COMPOSITIONS FOR TREATMENT OF PSORIATIC ARTHRITIS - The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriatic arthritis in a subject. | 09-04-2014 |
20140286867 | USE OF TNFALPHA INHIBITOR FOR TREATMENT OF EROSIVE POLYARTHRITIS - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 09-25-2014 |
Patent application number | Description | Published |
20150071938 | Use of TNFAlpha Inhibitor for Treatment of Psoriasis - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 03-12-2015 |
20150086569 | Use of TNFalpha Inhibitor for Treatment of Erosive Polyarthritis - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 03-26-2015 |
20150218268 | Use of TNFalpha Inhibitor for Treatment of Psoriasis - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 08-06-2015 |
20150218269 | USE OF TNFALPHA INHIBITOR FOR TREATMENT OF PSORIATIC ARTHRITIS - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 08-06-2015 |
Patent application number | Description | Published |
20080315453 | PROCESS FOR THE PRODUCTION OF POLYESTER NANOCOMPOSITES - A method for dispersing sepiolite-type clay particles in a polyester matrix by melt-compounding a mixture of: sepiolite-type clay, at least one linear polyester oligomer, and at least one polyester polymer to produce a nanocomposite composition; and, optionally, subjecting said nanocomposite composition to solid state polymerization to increase polyester molecular weight. Further described is a method for preparing a polyester nanocomposite composition from a masterbatch, comprising melt-compounding a mixture of: sepiolite-type clay, at least one polyester oligomer, and at least one polyester polymer to produce a nanocomposite composition containing a greater concentration of sepiolite-type clay than is desired in the final resin composition; optionally, subjecting said nanocomposite composition to solid state polymerization to increase the polyester molecular weight; and further melt compounding said nanocomposite composition with polyester polymer and, optionally, additional ingredients. | 12-25-2008 |
20090253320 | FLASH SPUN WEB CONTAINING SUB-MICRON FILAMENTS AND PROCESS FOR FORMING SAME - A nonwoven fibrous structure and process for forming it, which is an interconnecting web of polyolefin filaments having filament widths greater than about 1 micrometer which are further interconnected with webs of smaller polyolefin filaments having filament widths less than about 1 micrometer, wherein the smaller polyolefin filaments comprise a majority of all filaments. | 10-08-2009 |
20100273383 | CHITOSAN FILMS WITH REDUCED SHRINKAGE AND LAMINATES MADE THEREFROM - Inclusion of a needle structured clay or the plate structured clay sodium montmorillonite in a chitosan film was found to reduce shrinkage of the film. The clay is processed into a substantially dispersed form. Laminates fabricated from this chitosan film including dispersed clay can be used in make a variety of finished articles that can be used to provide protection from hazardous chemical and biological agents. | 10-28-2010 |
20110195624 | FLASH SPUN WEB CONTAINING SUB-MICRON FILAMENTS AND PROCESS FOR FORMING SAME - A nonwoven fibrous structure and process for forming it, which is an interconnecting web of polyolefin filaments having filament widths greater than about 1 micrometer which are further interconnected with webs of smaller polyolefin filaments having filament widths less than about 1 micrometer, wherein the smaller polyolefin filaments comprise a majority of all filaments. | 08-11-2011 |
20130052116 | CHITOSAN FILMS WITH REDUCED SHRINKAGE AND LAMINATES MADE THEREFROM - Inclusion of a needle structured clay or the plate structured clay sodium montmorillonite in a chitosan film was found to reduce shrinkage of the film. The needle structured clay is purified and processed into a substantially dispersed form by subjecting an aqueous slurry of the clay with water-soluble phosphate dispersant to a high pressure, high shear mixing process or to sonication. Laminates fabricated from chitosan film including dispersed clay can be used in make a variety of finished articles that can be used to provide protection from hazardous chemical and biological agents. | 02-28-2013 |
20130109791 | FLAME RETARDANT FLASH SPUN SHEETS | 05-02-2013 |
20140315459 | CHITOSAN FILMS WITH REDUCED SHRINKAGE AND LAMINATES MADE THEREFROM - Inclusion of a needle structured clay or the plate structured clay sodium montmorillonite in a chitosan film was found to reduce shrinkage of the film. The clay is processed into a substantially dispersed form. Laminates fabricated from this chitosan film including dispersed clay can be used in make a variety of finished articles that can be used to provide protection from hazardous chemical and biological agents. | 10-23-2014 |
Patent application number | Description | Published |
20100039199 | Polyamide electrical insulation for use in liquid filled transformers - An aliphatic polyamide film or fibrous material is employed for electrical insulation in individual conductors, groups of conductors, magnet wire, magnet wire coils, and layers in liquid filled electrical transformers. The material is stabilized with additives that produce improved moisture resistance, moisture stability, thermal stability, thermal conductivity, reduced insulation thickness, reduced shrinkage, and improved insulation elasticity for the insulation material thereby providing a longer useful life for the material. | 02-18-2010 |
20140022039 | POLYAMIDE ELECTRICAL INSULATION FOR USE IN LIQUID FILLED TRANSFORMERS - A transformer assembly is provided that includes a housing, transformer oil disposed within the housing, a plurality of coils of electrically conductive wire, and aliphatic polyamide insulation material operable to insulate the coils disposed within the oil. The plurality of electrically conductive coils is disposed in the housing and in contact with the transformer oil. The aliphatic polyamide insulation material includes stabilizing compounds and nano-fillers. The stabilizing compounds provide thermal and chemical stability for the insulation material. | 01-23-2014 |
20140062126 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 03-06-2014 |
20140147642 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 05-29-2014 |
20140230999 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 08-21-2014 |
20140231000 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 08-21-2014 |
20140234598 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 08-21-2014 |
20150009044 | DEVICE AND SYSTEM FOR PROTECTING A PERSON FROM RF RADIATION - A radiofrequency (“RF”) transmitter site protection system and an RF radiation protection device are provided. The RF radiation protection device includes a control system and a communication module. The control system includes a processor. The communication module is adapted to communicate with a device operable to sense RF radiation and to receive data representative of a level of the RF radiation proximate the RF safety monitoring device from the RF safety monitoring device. | 01-08-2015 |
20160039176 | COMPOSITE SHEET MATERIAL AND METHOD FOR FORMING THE SAME - A composite sheet material and method for forming the same is provided that includes a substrate, a matrix, and a cover sheet. The substrate has a first face surface, a second face surface, and a plurality of edges, and includes a thermoplastic material. The matrix is attached to the substrate. The matrix includes a support component having a first melting point, and a thermoplastic component having a second melting point. The second melting point is less than the first melting point. The cover sheet imparts one or more surface characteristics to the composite sheet material during thermo-pressure formation of the composite sheet material. | 02-11-2016 |
Patent application number | Description | Published |
20100225478 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 09-09-2010 |
20110132073 | Fatigue Testing System for Prosthetic Devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 06-09-2011 |
20110146385 | Fatigue evaluation of prostheses by radial excitation of tubular structures - Prostheses are fatigue tested using an apparatus under simulated physiological loading conditions. A fluid housing defines an entrance chamber having fluid outflow ports and an exit chamber having opposing fluid inflow ports and a central flow conduit in communication with the entrance chamber and the exit chamber. A plurality of housing tubes into which prosthesis are deployed may extend between the fluid outflow and inflow ports. Alternatively, tubular prostheses may be connected directly between the inflow and outflow ports. A reciprocating linear drive pump having a flexible diaphragm is provided to cyclically pressurize fluid through a common closed loop within the fluid housing and drive the pressurized fluid through the prosthesis being tested. The test system is capable of rotation independent of the motor drive for accurate diameter measurements of all test samples at elevated frequencies. | 06-23-2011 |
20120111489 | SELF-SEALING VASCULAR GRAFT - The present invention relates to a segmental self-sealing graft for implantation in a patient including a base tubing element, a tubular access element overlying the base tubing, and a strand-like compression element wound over the access element so as to provide radially inward compression, and a method of making same. | 05-10-2012 |
20140109651 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 04-24-2014 |
20150040644 | Fatigue testing system for prosthetic devices - A fatigue testing system provides simultaneous cycle testing for a plurality of prosthetic devices under simulated physiological loading conditions. A plurality of sample holders containing test samples of prosthetic devices is positioned between a distribution chamber and a return fluid chamber to form an integrated test chamber. A reciprocating linear drive motor operates a rolling bellows diaphragm to cyclically pressurize fluid within the test chamber and drive the pressurized fluid through the prosthetic devices being tested. The test chamber defines a return flow conduit in fluid communication with each of the sample holders, the return fluid chamber, and the distribution chamber. Compliance chambers and throttle valves associated with each of the sample holders regulate the pressure gradient and back pressure across the prosthetic devices being tested. | 02-12-2015 |
Patent application number | Description | Published |
20100286082 | RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH RIBOSWITCHES - Riboswitches are targets for antibiotics and other small molecule therapies. Riboswitches and portions thereof can be used to regulate the expression or function of RNA molecules and other elements and molecules. Riboswitches and portions thereof can be used in a variety of other methods to, for example, identify or detect compounds. Compounds can be used to stimulate, active, inhibit and/or inactivate the riboswitch. Riboswitches and portions thereof, both alone and in combination with other nucleic acids, can be used in a variety of constructs and RNA molecules and can be encoded by nucleic acids. | 11-11-2010 |
20120321647 | STRUCTURED RNA MOTIFS AND COMPOUNDS AND METHODS FOR THEIR USE - Disclosed are compositions and methods involing riboswitches and RNA motifs. For example, disclosed are compositions and methods involving glutamine-responsive riboswitches, S-adenosylmethionine-repsonsive riboswitches, S-adenosylhomocysteine-repsonsive riboswitches, glutamine riboswitches, SAM/SAH riboswitches, glnA riboswitches, Downstream-peptide riboswitches, crcB riboswitches, pfl riboswitches, yjdF riboswitches, manA riboswitches, wcaG riboswitches, epsC riboswitches, ykkC-III riboswitches, psaA riboswitches, psbA riboswitches, PhotoRC-I riboswitches, PhotoRC-II riboswitches, and psbNH riboswitches. | 12-20-2012 |
20130143955 | Cyclic di-GMP-II Riboswitches, Motifs, and Compounds, and Methods for Their Use - Disclosed are compositions and methods involving cyclic di-GMP—responsive Riboswitches and cyclic di-GMP-II motifs. | 06-06-2013 |
20150023889 | FLUORIDE-RESPONSIVE RIBOSWITCHS, FLUORIDE TRANSPORTERS, AND METHODS OF USE - Disclosed are compounds, compositions, and methods relating to fluoride aptamers, fluoride-responsive riboswitches, fluoride-regulated expression constructs, fluoride transporters, nucleic acids encoding fluoride transporters, expression constructs encoding fluoride transporters, and cells containing or including any combination of these. | 01-22-2015 |