Jain, PA
Anekant Jain, Allentown, PA US
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20150258020 | CHEWABLE TABLETS COMPRISING LEVONORGESTREL - The present invention relates to a chewable tablet comprising levonorgestrel and a pharmaceutically acceptable excipient for use in contraception, a method of use of same and a kit containing same. | 09-17-2015 |
Himanshu Jain, Bethlehem, PA US
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20100015244 | Nano/Macroporous Bioactive Glasses Made by Melt-Quench Methods - The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g. both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO—Na | 01-21-2010 |
20100272826 | NANO/MACROPOROUS BONE TISSUE SCAFFOLDS FOR REGENERATIVE MEDICINE - A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold. | 10-28-2010 |
20110057154 | CONDUCTIVE DOPED METAL-GLASS COMPOSITIONS AND METHODS - Provided herein are conductive glass-metal compositions, as well as methods of making and using such compositions. In one example, the compositions include gold (Au) doped lithium-borate glasses shown to exhibit a transition from ionic to electronic conduction within the same sample. This is achieved via appropriate heat treatment, and particularly by heat treatment after annealing, wherein the post-annealing heat treatment is performed at temperatures below the glass transition temperature (T | 03-10-2011 |
20120094122 | FABRICATION OF NANOPOROUS GLASS FIBER FOR FLEXIBLE BIOSCAFFOLDS AND OTHER PRODUCTS - Provided herein are novel nanoporous glass fibers, and methods of preparing and using such fibers. In some embodiments, articles are made from particular glass starting materials, such as soda-lime phosphosilicate glass fabricated by melt-quench methods. The articles include nanoporous fibers that can be used alone, or sewn, woven, bundled, and otherwise incorporated to form nanoporous articles, including bioactive articles. | 04-19-2012 |
20120189844 | METHODS TO FABRICATE NANO-MACRO POROUS GLASS USING A WATER SOLUBLE PORE FORMER - Provided herein are methods for preparing nano-macroporous glass articles, such as bioscaffolds, from starting materials such as phosphosilicate glasses made by melt-quench methods, mixed with a soluble pore former such as a sugar, followed by steps of dissolving, heating, and leaching to yield a glass composition having a highly interconnected system of both macropores and large scale nanoporosity. | 07-26-2012 |
20130256627 | Sensors Incorporating Freestanding Carbon NanoStructures - Sensors for detecting IR radiation, UV radiation, X-Rays, light, gas, and chemicals. The sensors herein incorporate freestanding carbon nanostructures, such as single-walled carbon nanotubes (“SWCNT”), atomically thin carbon sheets having a thickness of about between 1 atom and about 5 atoms (“graphene”), and combinations thereof. The freestanding carbon nanostructures are suspended above a substrate by a plurality of conductors, each conductor electrically connected to the carbon nanostructure. In one method of manufacture, a resonance chamber is formed under the carbon nanostructure by etching of the substrate, yielding a sensor wherein the resonance chamber is bounded by at least the substrate and the carbon nanostructure. | 10-03-2013 |
20140075993 | Fabrication of Porous Glass Bioscaffolds By Sol-Gel and Polymer Sponge Methods - Provided herein are biocompatible scaffolds and methods of preparing such bioscaffolds. The methods provide a superior high surface area, interconnected nanomacroporous bioactive glass scaffold, by combining a sol-gel process and polymer sponge replication methods. The formation of a uniformly nanoporous and interconnected macroporous bioscaffold is demonstrated using a starting material comprising a 70 mol % SiO2—30 mol % CaO glass composition as an example. The bioscaffold includes a series of open, interconnected macropores with size from 300 to 600 μm, as desired for tissue ingrowth and vascularization. At the same time, coexisting nanopores provide high-specific surface area (>150 m2/g), which is needed for enhancing the structure's degradation rate. These bioscaffolds hold promise for applications in hard tissue engineering. | 03-20-2014 |
20150118321 | BIOACTIVE GLASS PREPARATION AND USE - A process of preparing a glass comprising: (a) heating a mixture of precursor chemicals to a melt temperature to form a melt, the melt being characterized in that quenching the melt at or above a threshold temperature results in a spinodal phase seperation, and quenching the melt below the threshold temperature results in a droplet phase seperation; and (b) quenching the melt at or above the threshold temperature in a preheated mold to form the glass composition having the spinodal phase seperation. | 04-30-2015 |
20150353414 | CONDUCTIVE DOPED METAL-GLASS COMPOSITIONS AND METHODS - Provided herein are conductive glass-metal compositions, as well as methods of making and using such compositions. In one example, the compositions include gold (Au) doped lithium-borate glasses shown to exhibit a transition from ionic to electronic conduction within the same sample. This is achieved via appropriate heat treatment, and particularly by heat treatment after annealing, wherein the post-annealing heat treatment is performed at temperatures below the glass transition temperature (T | 12-10-2015 |
Nareshkumar Jain, Bristol, PA US
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20150126761 | IMPROVED PROCESS FOR THE PREPARATION OF TREPROSTINIL AND DERIVATIVES THEREOF - A method for the preparation of treprostinil and its derivatives is described. In contrast to prior art, this method utilizes an easily scalable enzymatic resolution of a key intermediate for making these compounds. Another significant improvement of the described method over prior methods is the regioselective Claisen rearrangement of a 5-allyloxy-benzaldehyde precursor, which is facilitated by a bromo substituent in 2-position. | 05-07-2015 |
Nareshkumar F. Jain, Exton, PA US
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20080221202 | STEROIDS DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS - The present invention is directed to novel steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by at least one progesterone or glucocorticoid receptor. | 09-11-2008 |
20100069474 | NOVEL COUMARIN DERIVATIVES AS ION CHANNEL OPENERS - The present invention is directed to novel coumarin derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders related to ion channels such as potassium channels | 03-18-2010 |
Puja Jain, Blue Bell, PA US
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20090214409 | Process for production of a borohydride compound - A process for production of a borohydride compound. The process comprises combining a compound comprising boron and oxygen with an adduct of alane. | 08-27-2009 |
Rajeev A. Jain, Norristown, PA US
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20080213371 | Rapidly disintegrating solid oral dosage form - Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity. | 09-04-2008 |
20090130213 | Rapidly disintegrating solid oral dosage form - Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, or less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity. | 05-21-2009 |
Siddhartha Jain, King Of Prussia, PA US
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20160074506 | DELIVERY OF SELF-REPLICATING RNA USING BIODEGRADABLE POLYMER PARTICLES - Particle compositions comprising adsorbed RNA replicons as well as methods of making and using the same are described. | 03-17-2016 |
Soumya Jain, Alentown, PA US
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20150159433 | MOTORIZED WINDOW TREATMENT - A motorized window treatment provides a low-cost solution for controlling the amount of daylight entering a space through a window. The window treatment includes a covering material, a drive shaft, at least one lift cord rotatably received around the drive shaft and connected to the covering material, and a motor coupled to the drive shaft for raising and lowering the covering material. The window treatment also includes a spring assist unit for assisting the motor by providing a torque that equals the torque provided by the weight on the cords that lift the covering material at a position midway between fully-open and fully-closed positions, which helps to minimize motor usage and conserve battery life if a battery is used to power the motorized window treatment. The window treatment may comprise a photosensor for measuring the amount of daylight outside the window and temperature sensors for measuring the temperatures inside and outside of the window. The position of the covering material may be automatically controlled in response to the photosensor and the temperature sensors to save energy, or may also be controlled in response to an infrared or radio-frequency remote control. | 06-11-2015 |
Soumya Jain, Allentown, PA US
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20120261078 | MOTORIZED WINDOW TREATMENT - A motorized window treatment controls daylight entering a space through a window and includes a covering material, a drive shaft, lift cords received around the drive shaft and connected to the covering material, and a motor coupled to the drive shaft. It also includes a spring assist unit for the motor providing a torque that equals the torque provided by the weight on the lift cords at a position midway between fully-open and fully-closed positions, minimizing motor usage and conserving battery life. A photosensor for measuring the daylight outside the window and temperature sensors for measuring the temperatures inside and outside of the window may be provided. The position of the covering material is automatically controlled to save energy, or may also be controlled in response to an infrared or radio-frequency remote control. | 10-18-2012 |
20140267008 | GESTURE-BASED LOAD CONTROL - A load control system may include load control devices for controlling an amount of power provided to an electrical load. The load control devices may be capable of controlling the amount of power provided to the electrical load based on control instructions received from a gesture-based control device. The gesture-based control device may identify gestures performed by a user for controlling a load control device and provide control instructions to the load control device based on the identified gestures. The gestures may be identified based on images received from a motion capture device. A gesture may be associated with a scene that includes a configuration of one or more load control devices in a load control system. The user may perform one or more gestures to program the gesture-based control device. | 09-18-2014 |
Sumeet Jain, Exton, PA US
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20140212792 | HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM - Articles for recording a holographic image are described. The articles include a holographic recording medium having a plurality of surfaces, having a transparent polymeric binder and a photochemically active dye, the holographic recording medium having a holographic image recorded therein formed by exposed areas of the photochemically active dye and unexposed areas of the photochemically active dye; and a first light-blocking layer or material over a first surface of the holographic recording medium from which surface the holographic image is viewed, the light blocking layer or material absorbing light in the wavelength range to which the photochemically active dye is sensitive and allowing transmission of light in a different wavelength range for viewing the holographic image. | 07-31-2014 |
Surbhi Jain, Doylestown, PA US
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20150361505 | Detection of hepatitis B virus (HBV) DNA and methylated HBV DNA in urine of patients with HBV-associated hepatocellular carcinoma - This application relates to a DNA marker for HBV-HCC detection and the methods, kits for quantitatively measuring the amount of HBV DNA and bisulfite treated HBV DNA, and methylated HBV DNA, and the aberrant methylation of the HBV genome for the used in the chronic HBV infected populations. Detection of the presence or absence of HCC, with elevated methylation levels in the one or more regions of DNA of the mammals as compared to the level of methylation in the one or more regions of DNA in the one or more control body fluids or tissues indicating the presence of the cancer, and the absence of elevated methylation levels indicating the absence of HCC. | 12-17-2015 |
Surbhi Jain, Lansdale, PA US
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20110256538 | EPIGENOMIC DNA MODIFICATIONS FOR TISSUE TYPING, EARLY CANCER DETECTION, AND DISEASE MANAGEMENT - Provided herein is a suitable method for detecting the presence or absence of a cancer in an individual, by determining the level of methylation of the sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of detecting the presence or absence a cancer in an individual by determining if there is an apparent 100% methylation by assay of the CpG sites in the anti-sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of tissue typing by determining the level of methylation of the anti-sense strand of a selected regulatory region of a tumor suppressor gene indicating an enhanced likelihood that a tissue is liver. | 10-20-2011 |