Tsong
Annie Ening Tsong, Emeryville, CA US
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20130236942 | PRODUCTION OF ACETYL-COENZYME A DERIVED ISOPRENOIDS - Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids. | 09-12-2013 |
20140154765 | PRODUCTION OF ACETYL-COENZYME A DERIVED ISOPRENOIDS - Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids. | 06-05-2014 |
20140273144 | USE OF PHOSPHOKETOLASE AND PHOSPHOTRANSACETYLASE FOR PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS - Provided herein are compositions and methods for improved production of acetyl-CoA and acetyl-CoA derived compounds in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding a phosphoketolase (PK), and a functional disruption of an endogenous enzyme that converts acetyl phosphate to acetate. In some embodiments, the host cell further comprises a heterologous nucleotide sequence encoding a phosphotransacetylase (PTA). In some embodiments, the enzyme that converts acetyl phosphate to acetate is a glycerol-1-phosphatase. In some embodiments, the glycerol-1-phosphatase is GPP1/RHR2. In some embodiments, the glycerol-1-phosphatase is GPP2/HOR2. The compositions and methods described herein provide an efficient route for the heterologous production of acetyl-CoA-derived compounds, including but not limited to, isoprenoids, polyketides, and fatty acids. | 09-18-2014 |
Ignatius S.t. Tsong, Tempe, AZ US
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20100012972 | Silicon-Germanium Hydrides and Methods for Making and Using Same - The present invention provides novel silicon-germanium hydride compounds, methods for their synthesis, methods for their deposition, and semiconductor structures made using the novel compounds. | 01-21-2010 |
20130032857 | Silicon-Germanium Hydrides and Methods for Making and Using Same - The present invention provides novel silicon-germanium hydride compounds, methods for their synthesis, methods for their deposition, and semiconductor structures made using the novel compounds. | 02-07-2013 |
I.s.t. Tsong, Tempe, AZ US
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20090324475 | Superhard dielectric compounds and methods of preparation - Novel superhard dielectric compounds useful as gate dielectrics in microelectronic devices have been discovered. Low temperature methods for making thin films of the compounds on substrate silicon are provided. The methods comprise the step of contacting a precursor having the formula H | 12-31-2009 |
Jun-Wen Tsong, San Jose, CA US
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20100254387 | NETWORK PROCESSOR ARCHITECTURE - A network processor for processing information elements is described. Each information element is associated with a flow and comprises at least one information element segment. A policy controller stores an information element into at least one information segment storage unit within a memory, and determines whether an information element segment conforms to a predetermined quality of service (“QoS”). A traffic processor selects the information element segment for forwarding based on at least one QoS parameter. A forwarding processor forwards the selected information element segment to an egress port. | 10-07-2010 |
20110314473 | SYSTEM AND METHOD FOR GROUPING MULTIPLE PROCESSORS - A distributed multi-processor out-of-order system includes multiple processors, an arbiter, a data dispatcher, a memory controller, a storage unit, multiple memory access requests issued by the multiple processors, and multiple data units that provide the results of the multiple memory access requests. Each of the multiple memory access requests includes a tag that identifies the priority of the processor that issued the memory access request, a processor identification number that identifies the processor that issued the request, and a processor access sequence number that identifies the order that the particular one of the processors issued the request. Each of the data units also includes a tag that specifics the processor identification number, the processor access sequence number, and a data sequence number that identifies the order of the data units satisfying the corresponding one of the memory requests. Using the tags, a distributed arbiter and data dispatcher can execute the requests out-of-order, handle simultaneous memory requests, order the memory requests based on, for example, the priority, return the data units to the processor that requested it, and reassemble the data units. | 12-22-2011 |
Tien T. Tsong, Taipei TW
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20090110951 | Atomically Sharp Iridium Tip - A method for preparing an iridium tip with atomic sharpness. The method includes tapering an iridium wire to a needle shape and heating the iridium needle in an oxygen atmosphere. Also disclosed is an iridium needle having a pyramidal structure which terminates with a small number of atoms prepared by the methods. | 04-30-2009 |
Tina Tsong, San Jose, CA US
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20110186545 | FEEDFORWARD TEMPERATURE CONTROL FOR PLASMA PROCESSING APPARATUS - Methods and systems for controlling temperatures in plasma processing chamber with reduced controller response times and increased stability. Temperature control is based at least in part on a feedforward control signal derived from a plasma power input into the processing chamber. A feedforward control signal compensating disturbances in the temperature attributable to the plasma power may be combined with a feedback control signal counteracting error between a measured and desired temperature. | 08-04-2011 |
20120132397 | TEMPERATURE CONTROL IN PLASMA PROCESSING APPARATUS USING PULSED HEAT TRANSFER FLUID FLOW - Methods and systems for controlling temperatures in plasma processing chamber via pulsed application of heating power and pulsed application of cooling power. In an embodiment, temperature control is based at least in part on a feedforward control signal derived from a plasma power input into the processing chamber. In further embodiments, fluid levels in each of a hot and cold reservoir coupled to the temperature controlled component are maintained in part by a passive leveling pipe coupling the two reservoirs. In another embodiment, digital heat transfer fluid flow control valves are opened with pulse widths dependent on a heating/cooling duty cycle value and a proportioning cycle having a duration that has been found to provide good temperature control performance. | 05-31-2012 |
Yun-Yen Tsong, North Caldwell, NJ US
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20080199511 | Sustained Release Compositions Containing Progesterone Receptor Modulators - Disclosed are sustained release compositions for vaginal or transdermal administration that contain a progesterone receptor modulator such as CDB-2914 (also referred to as VA-2914), and methods of using them for long term contraception or therapeutic purposes. Also disclosed are methods for making the compositions. | 08-21-2008 |