Patent application number | Description | Published |
20080233201 | Method for Preparing Calibrated Biodegradable Microspheres - The invention relates to a method for preparing monodispersed biodegradable microspheres consisting in a) preparing an emulsion containing at least one polymeric phase and at least one aqueous phase at a viscosity ratio between the dispersed polymeric phase and the aqueous phase ranging from 0.12 to 10, b) exposing the thus obtained emulsion to a controlled laminar shear strength, c) removing a solvent from the polymeric phase and in d) isolating the thus obtained microspheres. The use of the prepared microspheres is also disclosed. | 09-25-2008 |
20090005254 | Compartmentalized Screening by Microfluidic Control - The invention describes a method for the identification of compounds which bind to a target component of a bio-chemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into micro-capsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development. | 01-01-2009 |
20090197248 | VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 08-06-2009 |
20090197772 | Compartmentalised combinatorial chemistry by microfluidic control - The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules. | 08-06-2009 |
20100144899 | METHOD FOR PREPARING NANO-EMULSIONS - The present invention relates to a method for preparing nano-emulsions comprising at least one aqueous continuous phase and at least one oily dispersed phase, comprising the steps of:
| 06-10-2010 |
20100284932 | FLUORESCENT EMULSIONS FOR OPTICAL IMAGING - The invention relates to a fluorescent emulsion, to a diagnostic reagent containing the same, and to the use thereof in the preparation of a diagnostic reagent for in vivo fluorescence imaging. | 11-11-2010 |
20110188717 | METHOD AND DEVICE FOR READING AN EMULSION - A method for reading an emulsion ( | 08-04-2011 |
20110201695 | Encapsulation of lipophilic or amphiphilic therapeutic agents in nano-emulsion - The present invention relates to a therapeutic agent formulation in the form of a nano-emulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises further to the therapeutic agent, at least one amphiphilic lipid and at least one solubilising lipid, and in which the aqueous phase comprises at least one polyalkoxylated cosurfactant. | 08-18-2011 |
20120003285 | METHOD FOR MANUFACTURING CAPSULE SERIES, AND RELATED CAPSULE SERIES - A method includes separately conveying a first liquid solution ( | 01-05-2012 |
20130157872 | IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 06-20-2013 |
20130178368 | IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 07-11-2013 |
20130217601 | IN VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 08-22-2013 |
20130345348 | PROCESS FOR PREPARING A MASTERBATCH IN THE LIQUID PHASE - The invention relates to a process for the preparation of a masterbatch in the liquid phase based on one or more diene elastomer latexes and on one or more fillers, comprising the following successive stages:
| 12-26-2013 |
20140011922 | PROCESS FOR PREPARING A MASTERBATCH IN THE LIQUID PHASE - The invention relates to a process for the preparation of a masterbatch in the liquid phase based on one or more diene elastomers and on one or more fillers which do not coagulate spontaneously with the said latex, comprising the following successive stages:
| 01-09-2014 |
20140045949 | METHOD FOR FORMING DROPS OF A FIRST PHASE, DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE - This method includes the provision of a first fluid ( | 02-13-2014 |
20140065658 | Method for Monitoring A Reaction, And Reaction System For Implementing Same - The invention relates to a method for monitoring a reaction and to a reaction system which are inexpensive, compact, easy to implement, and enable the reaction medium to be fully supervised throughout the entire experiment. For this purpose, the invention relates to a reaction system, in particular for microorganism cultures, including: at least one vessel (M | 03-06-2014 |
20140069865 | METHOD FOR HIGH-THROUGHPUT SCREENING OF DROPS BY OSMOTIC EXCHANGE AND DENSITY VARIATION - This method comprises bringing drops to be separated into contact with an interface ( | 03-13-2014 |
20140377771 | Device and Method for Carrying out Haematological and Biochemical Measurements from a Biological Sample - The present invention concerns a device for analyzing biological parameters from a sample ( | 12-25-2014 |
20150017676 | CAPSULES CONTAINING MAMMALIAN CELLS - A capsule containing at least one mammalian cell, includes a liquid core, and at least one external envelope totally encapsulating the liquid core at its periphery, the external envelope including at least one gelled polyelectrolyte and/or a stiffened biopolymer and being able to retain the liquid core when the capsule is immersed in a gas. The present invention further relates to the method for preparing such a capsule, to a method for screening cosmetic active ingredients as well as a culture method using such capsules. | 01-15-2015 |
20150030648 | Dispersion intended for encapsulating an active product and associated use - A dispersion including a plurality of bodies dispersed in a continuous phase. Each dispersed body including an internal drop formed with an internal phase miscible with the continuous phase, the internal drop ( | 01-29-2015 |
20150044263 | Kit comprising two separate compositions, notably for cosmetic application - A kit comprising two separate compositions (A) and (B). Composition (A) is an aqueous gel with a viscosity of less than 11 Pa·s and contains at least one capsule including: a liquid core with at least one active ingredient and a gelled envelope totally encapsulating the liquid core. The gelled envelope includes at least one polyelectrolyte in the gelled state. Composition (B) includes a depolymerizing agent. | 02-12-2015 |
20150072146 | Method for Preparing Stiffened Capsules - The present invention relates to a method for preparing capsules comprising a liquid core, a stiffened intermediate envelope and a gelled external envelope, comprising a step of forming a multi-component liquid drop, a gelification step and a stiffening step. | 03-12-2015 |
20150087008 | Method For Monitoring A Reaction And To Reaction System For Implementing Same - A method for monitoring a reaction and a reaction system are provided. The reaction system includes at least one vessel for the reaction medium, which is in fluid communication with an injection tube; at least one vessel for a carrier fluid that is immiscible with the reaction medium, which is in fluid communication with a reaction tube; the injection tube being mounted so as to lead into the reaction tube such that individual drops of the reaction medium can be injected into the reaction tube and into the immiscible carrier fluid, so as to form a train of reaction chambers; at least one detector for monitoring a reaction; a means for classifying the reaction chambers; and at least one means for recirculating reaction chambers in front of at least one detector for monitoring a reaction. | 03-26-2015 |