Patent application number | Description | Published |
20100009860 | Device and method for analysis of interactions between biomolecules - The present invention relates to a device for the analysis of interactions between biomolecules comprising a support, on which a plurality of biomolecules are immobilized on the surface of a support material in a regular or irregular manner by a linker, whereby two biomolecules are bound to each linker. Further, the present invention relates to a method for the detection of interactions between biopolymers immobilized on a surface comprising the steps of providing a device of one of the preceding claims, adjusting a defined distance between two biopolymers immobilized on the surface and detection of a signal generated by the interaction between the two biopolymers. | 01-14-2010 |
20100041747 | USE OF CERTAIN CHEMICAL COMPOUNDS FOR THE INHIBITION OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE ACTIVITY OF CYCLOPHILINS - The present invention relates to the use of certain spiro, ketone and carboxylic acid compounds for the inhibition of the peptidyl-prolyl cis/trans isomerase activity of cyclophilins and the use of these compounds for the production of a cosmetic or pharmaceutical composition for the promotion of hair growth or for the treatment or prevention of inflammatory autoimmune diseases, of diseases caused by fungi, of bacterial infections, of viral infections, of diseases caused by parasites, protozoa or worms, of cancer, of diseases of cells, of fibrosing diseases, and of non-neoplastic changes and diseases which are attributable to prions and changes in the structure and function of cellular proteins and cells. | 02-18-2010 |
20100160175 | Catalysis of the cis/trans-isomerisation of secondary amide peptide compounds - The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity. | 06-24-2010 |
20120058932 | ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION - The present invention relates to an active ingredient-peptide construct for extracellular concentration, a process for the concentration of active ingredients in an extracellular space of a multicellular object, the use of the active ingredient-peptide construct according to the invention for the production of a medicinal product and a pharmaceutical composition containing the active ingredient-peptide construct according to the invention. | 03-08-2012 |
20120196749 | Cyclosporin Derivatives - A cyclosporin derivative of general Formula (I) or a pharmaceutically compatible salt thereof, which have a pharmaceutical effectiveness, for example in the case of chronic inflammatory diseases. The cyclosporin derivatives are preferably free from a peptide section capable of passing through the membrane of a biological cell. | 08-02-2012 |
20140316104 | CYCLOSPORIN DERIVATIVES - The present invention relates to novel cyclosporin derivatives that do not cross the cellular membrane. The compounds according to the invention are used in medicine, more particularly in the treatment/diagnosis of acute and chronic inflammatory diseases, viral infections, cancer, degenerative muscle diseases, neurodegenerative diseases and damage that is associated with calcium homeostasis impairment. The novel cyclosporin derivatives additionally have no immunosuppressive effect. | 10-23-2014 |
Patent application number | Description | Published |
20110229331 | Wind Turbine Rotor Blade - Wind turbine rotor blade with a longitudinal axis, a blade tip, a blade root, a leading edge, a trailing edge and a cross-section arranged orthogonally to the longitudinal axis and changing from the blade root to the blade tip, is the cross-section being formed at the blade root and in the middle of the rotor blade by an aerodynamic profile, and an imaginary reference plane arranged with respect to the rotor blade which includes the longitudinal axis of the rotor blade, wherein, in a cross-section, an angle α | 09-22-2011 |
20110229332 | Wind Turbine Rotor Blade - Wind turbine rotor blade with a blade tip, a blade root, a leading edge, a trailing edge, a pressure side, a suction side and a cross-section, which changes from the blade tip to the blade root, the longitudinal portion being arranged between the blade root and the middle of the rotor blade, has the following:
| 09-22-2011 |
20120219423 | Wind Turbine Rotor Blade with Varying Blade Depth - A wind turbine rotor blade has a blade root, a blade tip and a blade depth varying over the length of the rotor blade. The rotor blade has a maximum blade depth at a longitudinal position between the blade root and the blade tip. The blade depth in an outer longitudinal section, which extends over a length of 20% or more of the blade length, lies in a range from 20% to 30% of the maximum blade depth. | 08-30-2012 |
20130071253 | Wind Turbine Rotor Blade having a Thick Profile Trailing Edge - A wind turbine rotor blade having an aerodynamic profile which is formed in a longitudinal section of the rotor blade and which has a pressure side, a suction side, a profile leading edge and a profile trailing edge with a thickness of 3 mm or greater, characterized by a plurality of bristles which are arranged on the profile trailing edge and which are arranged in a suction-side row and in a pressure-side row, the suction-side row forming an aerodynamic surface which forms a smooth continuation of the suction side, and the pressure-side row forming an aerodynamic surface which forms a smooth continuation of the pressure side. | 03-21-2013 |