Douglas V.
Douglas V. Christini, North Brunswick, NJ US
Patent application number | Description | Published |
---|---|---|
20080269718 | Method for pressure mediated selective delivery of therapeutic substances and cannula - Methods and devices are disclosed for selective delivery of therapeutic substances to specific histologic or microanatomic areas of organs. Introduction of the therapeutic substance into a hollow organ space (such as an hepatobiliary duct or the gallbladder lumen) at a controlled pressure, volume or rate allows the substance to reach a predetermined cellular layer (such as the ephithelium or sub-epithelial space). The volume or flow rate of the substance can be controlled so that the intralumenal pressure reaches a predetermined threshold level beyond which subsequent subepithelial delivery of the substance occurs. Alternatively, a lower pressure is selected that does not exceed the threshold level, so that delivery occurs substantially only to the epithelial layer. Such site specific delivery of therapeutic agents permits localized delivery of substances (for example to the interstitial tissue of an organ) in concentrations that may otherwise produce systemic toxicity. Occlusion of venous or lymphatic drainage from the organ can also help prevent systemic administration of therapeutic substances, and increase selective delivery to superficial epithelial cellular layers. Delivery of genetic vectors can also be better targeted to cells where gene expression is desired. The access device comprises a cannula with a wall piercing tracar within the lumen. Two axially spaced inflatable balloons engage the wall securing the cannula and sealing the puncture site. A catheter equipped with an occlusion balloon is guided through the cannula to the location where the therapeutic substance is to be delivered. | 10-30-2008 |
20110263974 | METHOD FOR PRESSURE MEDIATED SELECTIVE DELIVERY OF THERAPEUTIC SUBSTANCES AND CANNULA - Methods and devices are disclosed for selective delivery of therapeutic substances to specific histologic or microanatomic areas of organs. Introduction of the therapeutic substance into a hollow organ space (such as an hepatobiliary duct or the gallbladder lumen) at a controlled pressure, volume or rate allows the substance to reach a predetermined cellular layer (such as the ephithelium or sub-epithelial space). The volume or flow rate of the substance can be controlled so that the intralumenal pressure reaches a predetermined threshold level beyond which subsequent subepithelial delivery of the substance occurs. Alternatively, a lower pressure is selected that does not exceed the threshold level, so that delivery occurs substantially only to the epithelial layer. Such site specific delivery of therapeutic agents permits localized delivery of substances (for example to the interstitial tissue of an organ) in concentrations that may otherwise produce systemic toxicity. Occlusion of venous or lymphatic drainage from the organ can also help prevent systemic administration of therapeutic substances, and increase selective delivery to superficial epithelial cellular layers. Delivery of genetic vectors can also be better targeted to cells where gene expression is desired. The access device comprises a cannula with a wall piercing tracar within the lumen. Two axially spaced inflatable balloons engage the wall securing the cannula and sealing the puncture site. A catheter equipped with an occlusion balloon is guided through the cannula to the location where the therapeutic substance is to be delivered. | 10-27-2011 |
Douglas V. Fougnies, Tempe, AZ US
Patent application number | Description | Published |
---|---|---|
20100009654 | PREPAID SECURITY CELLULAR TELECOMMUNICATIONS SYSTEM - A cellular telecommunications system having a security feature which allows only pre-authorized users to complete cellular telephone calls. The system and method recognizes a cellular radiotelephone's pre-programmed and pre-selected telephone number and an automated number identification code (ANI). The pre-selected telephone number is reserved to the pre-paid cellular telecommunications system. The cellular radiotelephone transmits the ANI and a dialed number identification system code (DNIS) to a cellular switch, which contacts a host computer for call validation by the pre-paid service provider. This system also allows pre-authorized users to receive and pay for incoming calls as well as purchase additional airtime and monthly access fees with convenient pre-paid cards. | 01-14-2010 |
Douglas V. Limbaugh, Glendale, AZ US
Patent application number | Description | Published |
---|---|---|
20090088074 | ENCLOSED SPACE COMMUNICATION SYSTEMS AND RELATED METHODS - Systems and methods for communication in enclosed areas. Implementations of a method may include sending a first high frequency (HF) signal using a first HF radio, receiving the first HF signal with a first medium frequency (MF) repeater, converting the first HF signal to an MF signal using the first MF repeater, and sending the MF signal to one or more second MF repeaters located in an enclosed space. The method may include receiving the MF signal with the one or more second MF repeaters, converting the MF signal to a second HF signal using the one or more second MF repeaters, and sending the second HF signal to a second HF radio. Implementations of radio communication systems may utilize MF repeaters with MF antennas which may be omnidirectional. | 04-02-2009 |
20090248287 | UNMANNED AERIAL SYSTEM POSITION REPORTING SYSTEM AND RELATED METHODS - Methods of communicating the location of an unmanned aerial system (UAS). Implementations of the method may include receiving position data for a UAS with an air traffic control reporting system (ATC-RS) from a ground control station (GCS) in communication with the UAS, where the ATC-RS and the GCS are coupled together and located on the ground. The method may include transmitting the position data using one or more telecommunication modems included in the ATC-RS to an air traffic control center (ATC) and transmitting the position data using an automatic dependent surveillance broadcast (ADS-B) and traffic information services broadcast (TIS-B) receiver to one or more aircraft. | 10-01-2009 |
20100066604 | UNMANNED AERIAL SYSTEM POSITION REPORTING SYSTEM - An unmanned aerial system (UAS) position reporting system. Implementations may include an air traffic control reporting system (ATC-RS) coupled with a ground control station (GCS) of an unmanned aerial system where the ATC-RS includes an automatic dependent surveillance broadcast (ADS-B) and a traffic information services broadcast (TIS-B) transceiver and one or more telecommunications modems. The ATC-RS may be adapted to receive position data of the UAS in an airspace from the GCS and communicate the position of the UAS in the airspace to a civilian air traffic control center (ATC) or to a military command and control (C2) communication center through an ADS-B signal or through a TIS-B signal through the ADS-B and TIS-B transceiver. The ATC-RS may also be adapted to display the position of the UAS in the airspace on one or more display screens coupled with the ATC-RS. | 03-18-2010 |
Douglas V. Limbaugh, Phoenix, AZ US
Patent application number | Description | Published |
---|---|---|
20140025282 | UNMANNED AERIAL SYSTEM POSITION REPORTING SYSTEM - An unmanned aerial system (UAS) position reporting system may include an air traffic control reporting system (ATC-RS) coupled with a ground control station (GCS) of an unmanned aerial system. The ATC-RS may include an automatic dependent surveillance broadcast (ADS-B) and traffic information services broadcast (TIS-B) transceiver and one or more telecommunications modems. The ATC-RS may be adapted to receive position data of the UAS in an airspace from the GCS and to selectively communicate the position of the UAS in the airspace to a civilian air traffic control center (ATC), to a military command and control (C2) communication center, or to both the civilian ATC and the military C2 communication center through the ADS-B and TIS-B transceiver. The ATC-RS may also be adapted to display the position of the UAS in the airspace on a display screen coupled with the ATC-RS. | 01-23-2014 |
Douglas V. O'Dell, Iii, Montclair, NJ US
Patent application number | Description | Published |
---|---|---|
20140289161 | DYNAMICALLY GUIDED USER REVIEWS - Systems and associated processes for guiding users to provide more useful reviews are described. These systems and processes can provide guided reviews in certain embodiments by presenting questions to a user in the form of an interview. The questions can be relevant to the item being reviewed, and as such, may be specifically and dynamically selected based on the particular item under consideration. Many other criteria may be used to select the types of questions presented to users, examples of which will be described below. Presenting review questions to users can have the effect of reducing or eliminating the “blank page” effect of having to write a review from scratch, with no guidance. Accordingly, review questions can potentially elicit more thorough and useful feedback than existing review systems in some embodiments. | 09-25-2014 |