Voet
Arnout Voet, Wakoshi JP
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20150336965 | NOVEL ANTIVIRAL COMPOUNDS - The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection. | 11-26-2015 |
Arnout Voet, Heverlee BE
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20120059028 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS - The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity. | 03-08-2012 |
20140296272 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS - The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity. | 10-02-2014 |
Arnout Voet, Zwevegem BE
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20120129840 | NOVEL VIRAL REPLICATION INHIBITORS - The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity. | 05-24-2012 |
20120316161 | NOVEL ANTIVIRAL COMPOUNDS - The present invention relates to compounds of formula (A) as defined herein having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity. | 12-13-2012 |
20130245049 | Novel Antiviral Compounds - The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection. | 09-19-2013 |
20150051195 | NOVEL VIRAL REPLICATION INHIBITORS - The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity. | 02-19-2015 |
Hans Voet, Hulshout BE
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20110034109 | FLOOR LEVELLING VEHICLE - This invention relates to a mobile floor levelling vehicle for levelling an undulating floor surface, which comprises a vehicle body with front and back displacement means for moving the vehicle body. To carry out the levelling operation the floor levelling vehicle comprises at least one grinding tool which is provided and driven to remove an amount of material from the floor, and at least one additional polishing device provided at a position behind the back displacement members in moving direction of the levelling vehicle. | 02-10-2011 |
20140242863 | ARTICLE OF MANUFACTURE MADE OF COMPOSITE MATERIAL, FOR INCORPORATION INTO A CIVIL ENGINEERING STRUCTURE - An article of manufacture is disclosed for incorporating into a civil engineering structure, for example a concrete structure, such as a floor. The article comprises a substantially fully cured thermosetting polymer resin and a particulate aggregate material having a Mohs hardness of from 3 to 9, preferably from 5 to 8. The article optionally comprises a reinforcing fiber. | 08-28-2014 |
20150039184 | SYSTEM FOR REDUCING ROLL AND PITCH IN A MOVING VEHICLE - A vehicle is disclosed designed for traveling on a traveling surface. The vehicle comprises a detection means for detecting irregularities in the traveling surface. From the detected irregularities in the traveling surface a first kinematic effect is calculated that is being exerted, or about to be exerted, on a support wheel of the vehicle. The vehicle further comprises an actuator that exerts a second kinematic effect on the support wheel. The second kinematic effect is identical or similar in magnitude to the first kinematic effect, and opposite in sign. The vehicle can be any vehicle, in particular an industrial vehicle, more particularly a vehicle that can be extended to a height exceeding its wheelbase. | 02-05-2015 |
Jan Voet, Schilde BE
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20150055509 | COMMUNICATIONS DEVICE UTILIZING A CENTRAL DISCOVERY MECHANISM, AND RESPECTIVE METHOD - The communications device comprises one or several participants communicating with each other and with participants of other devices of a network via endpoints, wherein the communications device comprises a central discovery handler storing discovery information of the participants in a memory for providing a central discovery for the participants of the network, and when the central discovery handler detects a match between an endpoint of a first participant and an endpoint of a second participant, then the central discovery handler informs the first and the second participant about the match. | 02-26-2015 |
Marc Voet, Rocles FR
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20100175460 | DEVICE, SYSTEM, AND METHOD FOR DETECTING AND LOCATING MALFUNCTIONS IN A HYDRAULIC STRUCTURE, AND A HYDRAULIC STRUCTURE WITH SAID DEVICE - The invention relates to a device ( | 07-15-2010 |
Pierre Voet, Rixensart BE
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20080233154 | Vaccine Composition - The present invention relates to an immuno-protective and non-toxic Gram-negative bleb vaccine suitable for paediatric use. Examples of the Gram-negative strains from which the blebs are made are | 09-25-2008 |
20090117147 | VACCINES COMPRISING OUTER MEMBRANE VESICLES FROM GRAM NEGATIVE BACTERIA - The present invention relates to the field of vaccine formulation, particularly the field of novel adjuvant compositions comprising outer membrane vesicles (or blebs), and advantageous methods of detoxifying these compositions, and advantageous methods of use of such adjuvants. | 05-07-2009 |
20140294935 | VACCINE COMPOSITION - The present invention relates to an immuno-protective and non-toxic Gram-negative bleb vaccine suitable for paediatric use. Examples of the Gram-negative strains from which the blebs are made are | 10-02-2014 |
Thierry Voet, Heverlee BE
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20130085082 | METHODS FOR HAPLOTYPING SINGLE CELLS - We developed a generic approach to type genome-wide single nucleotide polymorphisms in single human cells and to reconstruct for the first time genome-wide haplotypes of single- or dual-cell derived genotypes. Proof-of-principle is delivered for EBV-transformed lymphoblastoid cells as well as human blastomeres. To this end, multiple displacement amplified DNA samples of single cells were hybridized to Affymetrix 250K SNP-arrays. Different algorithmic designs were subsequently developed to assess from the single-cell derived SNP-probe intensities the sequence of syntenic alleles and to pinpoint accurately the majority of parental homologous recombination sites across the entire genome using a linkage-based approach. This included the development of algorithms that rectify a large part of the discrepant allelic assignments in raw single or dual-cell derived haplotypes. This method to infer genome-wide haplotypes from the analysis of only one or two cells has tremendous applicative value. It has the capacity to revolutionize not only genetic diagnosis of preimplantation in vitro fertilized human embryos in the clinic, but also animal breeding programs by enabling genome-wide quantitative trait loci selection at the embryonic level. In addition, it allows to further scrutinize drivers of haplotype diversity, mainly meiotic homologous recombination as well as somatic (homologous) recombination processes that occur often during (human) tumorigenesis. | 04-04-2013 |
20150247184 | HIGH-THROUGHPUT GENOTYPING BY SEQUENCING LOW AMOUNTS OF GENETIC MATERIAL - The present invention provides a method for analysis of target nucleic acids which are present in low amounts. In particular, the method comprises the following steps: i. providing a sample wherein target nucleic acids are present in a low amount, ii. generating a reduced representation library of said target nucleic acids by a method comprising: fragmenting said target nucleic acids; ligating adaptors to said fragments; and selecting a subset of said adaptor-ligated fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing. | 09-03-2015 |
William Voet, Butler, KY US
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20140062039 | QUICK-CHANGE TOP TOOLING - A quick-change top tooling system is provided to accommodate various sized and configurations of workpieces to be chucked. The quick-change top tooling system includes a chuck body, at least one jaw assembly, and at least one workstop assembly. The jaw assembly comprises a master post fixed to a surface of the chuck body and a jaw releasably coupled to the master post. The workstop assembly comprises a workstop base mounted to the surface of the chuck body and a workstop releasably coupled to the workstop base. The at least one jaw and workstop may engage and clamp a workpiece to be chucked to maintain the concentricity and parallelism of the workpiece. | 03-06-2014 |