Patent application number | Description | Published |
20090286965 | MUTANT GROWTH FACTORS WITH ALTERED RECEPTOR SPECIFICITIES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME - Disclosed is a mutant protein having an altered fibroblast growth factor receptor specificity, which is produced by deleting one or more amino acid residues from the N-terminus of the amino acid sequence of naturally secreted fibroblast growth factor 18. The protein mutant can be used in a pharmaceutical composition for regulating hair regeneration or growth or a pharmaceutical composition for regulating bone or cartilage formation. | 11-19-2009 |
20100183733 | HAIR GROWTH-INHIBITING AGENT - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract). | 07-22-2010 |
20100184665 | METHOD FOR ACTIVATING RECEPTOR BY COFACTOR AND METHOD FOR UTILIZING LIGAND ACTIVITY - Using betaKlotho or a substance that increases or inhibits betaKlotho activity as an agent for controlling the activity of FGF21 mediated by an FGF receptor, the present invention provides a pharmaceutical composition comprising such betaKlotho or such substance as an active ingredient, particularly, a pharmaceutical composition for anti-metabolic syndrome, and further particularly, a pharmaceutical composition for therapeutic or preventive use associated with the control of blood glucose level. In addition, the present invention provides a screening system for each of a substance that enhances or suppresses betaKlotho activity, an FGF21-like active substance, and a betaKlotho-like active substance, which uses a cell system that has expressed an FGF receptor and/or betaKlotho on the surface thereof. | 07-22-2010 |
20100203055 | HAIR REGROWTH PROMOTER - It is intended to provide a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia by determining an endogenous factor that inhibits hair growth and screening for substances that inhibit the activity or expression of the endogenous factor. It has been found that FGF18 inhibits hair growth. A method of screening for substances that inhibit the activity of FGF18 or substances that inhibit the expression of FGF18 to thereby obtain candidates for the hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia is disclosed. Also disclosed is a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia comprising, as an active ingredient(s), a substance that inhibit the activity of FGF18 and/or a substance that inhibits the expression of FGF18 such as a partial peptide of FGF18 or a | 08-12-2010 |
20100286042 | Medicinal Composition Containing Highly Functionalized Chimeric Protein - There is provided an FGF2 substitute containing medicinal composition which comprises, as an active ingredient, a chimeric protein comprising the amino acid sequence of an FGF1 protein in which a partial sequence including a sequence of at least positions 62-83 within a sequence of positions 41-83 is substituted with a partial sequence at the corresponding positions in the amino acid sequence of an FGF2 protein; and the remaining region is formed of the amino acid sequence of FGF1. In particular, this medicinal composition is used for wound healing and for the prevention and treatment of radiation-induced damage, and it exhibits a pharmacological action superior to that of an FGF2 medicinal composition, and further, it can be easily formulated into a preparation. | 11-11-2010 |
20120214740 | Medicinal Compositions Containing Highly Functionalized Chimeric Protein - There is provided an FGF2 substitute-containing medicinal composition which comprises, as an active ingredient, a chimeric protein comprising the amino acid sequence of an FGF1 protein in which a partial sequence including a sequence of at least positions 62-83 within a sequence of positions 41-83 is substituted with a partial sequence at the corresponding positions in the amino acid sequence of an FGF2 protein; and the remaining region is formed of the amino acid sequence of FGF1. In particular, this medicinal composition is used for wound healing and for the prevention and treatment of radiation-induced damage, and it exhibits a pharmacological action superior to that of an FGF2 medicinal composition, and further, it can be easily formulated into a preparation. | 08-23-2012 |
20120251455 | Hair Growth-Inhibiting Agent - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract). | 10-04-2012 |
Patent application number | Description | Published |
20090213401 | IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD - An image forming apparatus capable of accurately compensating an increase or decrease of a toner area coverage resulting from shifting that is performed to correct skew is provided. A color density of image data represented by a correction target pixel is corrected such that the increase or decrease in the toner area coverage on the correction target pixel is compensated excluding a toner area coverage on the correction target pixel covered by a toner image that would be formed based on a color density of image data to be represented by a neighboring pixel of the correction target pixel. This effectively reduces banding noise on an output of the image data and prevents degradation in image quality. | 08-27-2009 |
20090231606 | METHOD AND APPARATUS FOR IMAGE FORMING AND COMPUTER PROGRAM PRODUCT - An image forming apparatus capable of minimizing degradation in density correction as a part of skew correction includes a noise-occurrence determining unit, a correction-target-pixel selecting unit, a density correcting unit, and a phase correcting unit. When the noise-occurrence determining unit determines that noise would appear, the density correcting unit performs density correction on a correction target pixel that is determined by the correction-target-pixel selecting unit. The phase correcting unit corrects an output point in time of image data of the density-corrected correction target pixel in a pixel period during which the image data can be output so as to output the image data at a position displaced away from a shift position or toward a shift position. | 09-17-2009 |
20100253981 | IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND COMPUTER PROGRAM PRODUCT - An image forming apparatus includes a skew correcting unit that performs skew correction by dividing an input image that has undergone a halftone process into image data in a predetermined skew correction area in a main scanning direction and by shifting the image data in the skew correction area in a sub-scanning direction; an edge detecting unit that detects whether a pixel at a division position is an edge pixel based on concentrations of a set of pixels including the pixel at the division position; a correction area determining unit that, if detected that the pixel at the division position is the edge pixel, determines a correction area that is an area of pixels including the edge pixel to be subjected to concentration correction within the skew correction area; and an edge correcting unit that corrects concentrations of the pixels within the correction area. | 10-07-2010 |
20140063168 | LIGHT-EMITTING SUBSTRATE, METHOD FOR MANUFACTURING THE SAME, OPTICAL WRITING DEVICE, AND IMAGE FORMING APPARATUS - A light-emitting substrate including: a first and second light-emitting devices each including terminals; and a substrate including a first hole and a second hole, the first hole and the second hole respectively having at least one receiving portion, wherein the receiving portion of the first hole receives the terminal of the first light-emitting device, and the receiving portion of the second hole receives the terminal of the second light-emitting device, a first line drawn through a center of the receiving portion of the first hole and a center of the first hole, and a second line drawn through a center of the receiving portion of the second hole and a center of the second hole are not aligned in line. | 03-06-2014 |
20140168343 | WRITING CONTROLLING APPARATUS, IMAGE FORMING APPARATUS, AND COMPUTER PROGRAM PRODUCT - The invention is concerning the writing controlling apparatus that includes an acquiring unit configured to acquire a plurality of light amounts of a light source driven while changing an input current in non-effective scanning periods during which an image carrier is not irradiated with light from the light source, as a plurality of output results; a detecting unit configured to detect characteristics of the light source using the output results thus acquired; and a correcting unit configured to correct a current to be applied to the light source based on the characteristics thus detected. | 06-19-2014 |
20140198469 | ELECTRONIC CIRCUIT, LIGHT SOURCE DEVICE, AND METHOD OF MANUFACTURING ELECTRONIC CIRCUIT - An electronic circuit having an electronic component mounted on a substrate, a light source device having the electronic circuit, and a method of manufacturing the electronic circuit on which the electronic component is mounted on the substrate are described. The electronic component has a plurality of lead pins to be electrically connected to wirings on the substrate. The substrate is formed with a hole having a larger dimension than a maximum distance between at least two lead pins of the lead pins. The lead pins are inserted into the hole from sides of tips of the lead pins while being bent at a plurality of bending portions, and fixed to the substrate by a solder. | 07-17-2014 |
Patent application number | Description | Published |
20100003210 | EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION - To provide An external skin agent that prevents onset of atopic skin inflammations and is low irritant to skin, which is characterized by including: 1) clay modified by a compound having a quaternary amino group; and 2) a polymer or copolymer that has a side chain including a structure similar to a biological component. | 01-07-2010 |
20100055220 | SKIN EXTERNAL PREPARATION IN THE FORM OF WATER-IN-OIL EMULSION COMPRISING CERAMIDE - A technology for delivering a ceramide across the horny layer of skin to sufficiently exert the effects of the ceramide is disclosed. Specifically, an external preparation for skin containing a ceramide delivers the ceramide across the horny layer to near the dermis when the skin preparation is applied on the skin surface. The described skin external preparation contains a ceramide, an organically modified clay mineral, a diester of N-acylglutamic acid, and a phytosterol as components in the form of water-in-oil emulsion. | 03-04-2010 |
20140235577 | EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION - To provide An external skin agent that prevents onset of atopic skin inflammations and is low irritant to skin, which is characterized by including: 1) clay modified by a compound having a quaternary amino group; and 2) a polymer or copolymer that has a side chain including a structure similar to a biological component. | 08-21-2014 |
20150051170 | EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION - To provide an external skin agent that prevents onset of atopic skin inflammations and is low irritant to skin, which is characterized by including: 1) clay modified by a compound having a quaternary amino group; and 2) a polymer or copolymer that has a side chain including a structure similar to a biological component. | 02-19-2015 |
Patent application number | Description | Published |
20130137369 | WIRELESS COMMUNICATION DEVICE, POWER TRANSMITTER, AND IC CARD DEVICE - A wireless communication device has a power receiving wireless communication unit configured to receive power and perform wireless communication utilizing the power, a storage unit configured to store a portion of the power, and a first wireless communication unit configured to perform wireless communication faster and more efficiently than the power receiving wireless communication unit by utilizing the power stored in the storage unit, when amount of the power stored in the storage unit exceeds a first reference level. The power receiving wireless communication unit includes a power receiver configured to receive power and supply a portion of the power to the storage unit, and a second wireless communication unit configured to perform wireless communication slower and less efficiently than the first wireless communication unit by utilizing the power received by the power receiver. | 05-30-2013 |
20140073247 | MOBILE WIRELESS DEVICE, WIRELESS COMMUNICATION SYSTEM AND, WIRELESS COMMUNICATION METHOD - A mobile wireless device has a first communication unit configured to perform proximity wireless communication with a communication device, a certification unit configured to perform a certification process between the mobile wireless device and the communication device via the proximity wireless communication using the first communication unit, a second communication unit configured to perform proximity wireless communication with an extra mobile wireless device, and an operation controller configured to control the extra mobile wireless device via the proximity wireless communication using the second communication unit, after the certification process is normally completed. | 03-13-2014 |