Alan O.
Alan O. Lebeck, Albuquerque, NM US
Patent application number | Description | Published |
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20100001220 | ROTARY FACE SEAL WITH ANTI-CROWNING FEATURES - A typical rotary face seal employs a seal ring rotating relative to a sealing surface and also employs means to urge the seal ring towards the sealing surface in order to effect a seal. The seal ring may itself comprise a seal face bonded to a backing ring. In certain applications, the seal face may deform significantly as a result of the temperature variations experienced and an undesirable crowning of the seal face may occur. Such crowning may be reduced by employing an improved seal ring with anti-crowning features in which the thickness of an edge of the seal face is different from that in the middle of the seal face, or in which a relief slot is employed in the seal face. The improved seal ring is particularly suited for rotary face seals used in a rotary valve in a rotary gas separation device. | 01-07-2010 |
Alan O. Perantoni, Mechanicsburg, PA US
Patent application number | Description | Published |
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20100184697 | PEPTIDE-BASED STAT INHIBITOR - A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT protein in a cell, a method of treating or preventing a disease associated with STAT overexpression in a host, and related compounds, compositions, and methods. | 07-22-2010 |
Alan O. Perantoni, Fairfield, PA US
Patent application number | Description | Published |
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20130109619 | PEPTIDE-BASED INHIBITOR OF INTERLEUKIN-10 OR INTERFERON-GAMMA SIGNALING | 05-02-2013 |
20130273058 | SYNTHETIC PEPTIDE INHIBITORS OF WNT PATHWAY - A peptide or peptidomimetic comprising the amino acid sequence KKRLSVXLTSSLFR (SEQ ID NO: 1) or the inverse thereof, or comprising at least eight contiguous amino acids of helix C of β-catenin (SEQ ID NO: 41) or inverse thereof, wherein the peptide or peptidomimetic comprises a total of about 50 or fewer amino acids and inhibits the Wnt pathway, as well as a method of inhibiting the Wnt pathway in a cell, a method of treating or preventing a disease mediated by the Wnt pathway, and related compounds, compositions, and methods. | 10-17-2013 |