Rouleau
Christian Rouleau, Quebec CA
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20100049361 | MEDICATION DISPENSING SYSTEM AND METHOD - A medication dispensing system and method where the patient can have his personal console capable of receiving an insert having a tray with an array of medication compartments corresponding to respective times and dates at which the medication is prescribed to be taken. A database in the console can be set with the specified times and dates at which the medication is to be taken. When the console determines the time to dispense medication in one of the compartments has been reached, a visual and/or audible indicator can be triggered. Membranes which are to be hand-removed by the patient cover the respective compartments. A detector provided under the insert can detect across the tray whether or not the membrane corresponding to the selected medication compartment has been removed. | 02-25-2010 |
Guy Rouleau, Montreal CA
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20110229891 | SYNGAP1 DYSFUNCTIONS AND USES THEREOF IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS FOR MENTAL RETARDATION - The invention identifies Syngap1 dysfunctions as causative of mental retardation. Described are methods of detecting mental retardation and methods of detecting non-syndromic mental retardation (NSMR) in a human subject. Particular methods comprise sequencing a human subject's genomic DNA for comparison with a control sequence from an unaffected individual. Also described are probes, kits, antibodies and isolated mutated Syngap1 proteins. | 09-22-2011 |
20130065238 | SYNGAP1 DYSFUNCTIONS AND USES THEREOF IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS FOR MENTAL RETARDATION - The invention identifies Syngap1 dysfunctions as causative of mental retardation. Described are methods of detecting mental retardation and methods of detecting non-syndromic mental retardation (NSMR) in a human subject. Particular methods comprise sequencing a human subject's genomic DNA for comparison with a control sequence from an unaffected individual. Also described are probes, kits, antibodies and isolated mutated Syngap1 proteins. | 03-14-2013 |
20140057971 | LaFORA'S DISEASE GENE - A novel gene (EPM2A) that is deleted or mutated in people with Lafora's disease is described. The EPM2A gene encodes a protein having an active catalytic site of a protein tyrosine phosphatase. Many different sequence mutations as well as several microdeletions in EPM2A have been found that co-segregate with Lafora's disease. | 02-27-2014 |
Guy A. Rouleau, Montreal CA
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20090061431 | Method of prognosing and diagnosing hereditary spastic paraplegia, mutant nucleic acid molecules and polypeptides - A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. | 03-05-2009 |
20090148855 | NUCLEIC ACID ENCODING OR TARGETING SODIUM CHANNEL SCN3A ALPHA SUBUNITS - The present invention relates to epilepsy. More particularly, the present invention relates to idiopathic generalized epilepsy (IGE) and to the identification of three genes mapping to chromosome 2, which show mutations in patients with epilepsy. The invention further relates to nucleic acid sequences, and protein sequences of these loci (SCNA) and to the use thereof to assess, diagnose, prognose or treat epilepsy, to predict an epileptic individual's response to medication and to identify agents which modulate the function of the SCNA. The invention also provides screening assays using SCN1A, SCN2A and/or SCN3A which can identify compounds which have therapeutic benefit for epilepsy and related neurological disorders. | 06-11-2009 |
20100092990 | NUCLEIC ACIDS ENCODING SODIUM CHANNEL SCN1A ALPHA SUBUNIT PROTEINS AND MUTATIONS ASSOCIATED WITH EPILEPSY - The present invention relates to epilepsy. More particularly, the present invention relates to idiopathic generalized epilepsy (IGE) and to the identification of three genes mapping to chromosome 2, which show mutations in patients with epilepsy. The invention further relates to nucleic acid sequences, and protein sequences of these loci (SCNA) and to the use thereof to assess, diagnose, prognose or treat epilepsy, to predict an epileptic individual's response to medication and to identify agents which modulate the function of the SCNA. The invention also provides screening assays using SCN1A, SCN2A and/or SCN3A which can identify compounds which have therapeutic benefit for epilepsy and related neurological disorders. | 04-15-2010 |
20110218122 | METHOD OF PROGNOSING AND DIAGNOSING HEREDITARY SPASTIC PARAPLEGIA, MUTANT NUCLEIC ACID MOLECULES AND POLYPEPTIDES - A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. | 09-08-2011 |
20140065724 | METHOD OF PROGNOSING AND DIAGNOSING HEREDITARY SPASTIC PARAPLEGIA, MUTANT NUCLEIC ACID MOLECULES AND POLYPEPTIDES - A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. | 03-06-2014 |
Hugues Rouleau, Saint-Redempteur CA
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20100313480 | WINDOW WITH ELECTRICAL CONNECTION TO OPERABLE SASH - The window has a sash mounted in a frame, the sash having an electrical system and being selectively operable into one of a closed state and an open state, a lock between the sash and the frame, the lock being selectively operable into one of a locked state and an unlocked state, an electrical connection connecting the frame and the electrical system of the sash, and a sensor-switch device which senses the open state and which causes the electrical connection to be open when the sash is in the open state | 12-16-2010 |
Louis Sebastien Rouleau, Blainville CA
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20080232584 | HAND-HELD DECODER CARD HAVING A PARALLAX BARRIER PORTION AND A LIGHT FILTERING PORTION AND METHOD OF MAKING SAME - The present document describes a hand-held decoder card for revealing information hidden in a printed material and information hidden in a color image and method of making the same. The hand-held decoder card comprises: translucent material having a parallax barrier portion comprising parallel barrier lines for revealing the information hidden in the printed material; and the translucent material having a light filtering portion comprising a light filter for revealing the information hidden in the color image. According to various embodiments, the hand-held decoder card is in a transactional card format. The card may include only the parallax barrier portion or the light filtering portion. Also, the hand-held card may be a monocoque card or a laminated card. | 09-25-2008 |
Pascal Rouleau, Quebec CA
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20090275516 | COMPOUNDS AND METHOD FOR MODULATING INFLAMMATORY REACTIONS - The present invention relates to compounds and methods for modulating, reducing or inhibiting, inflammatory reactions in a patient. Particularly, inflammatory reactions that are targeted by the present invention are cell migration, secretion of toxic products and proteolysis at a site of inflammation. Reduction of inflammation manifestations and reactions occurs by using an anti-S100 polynucleotide or polypeptide inhibitor or antagonist, which is essentially targeted against S100A8, S100A9 or S100A12, alone or in combination with other inhibitors of chemokines or immune modulating products. | 11-05-2009 |
20130273075 | Compounds and Method for Modulating Inflammatory Reactions - The present invention relates to compounds and methods for modulating, reducing or inhibiting, inflammatory reactions in a patient. Particularly, inflammatory reactions that are targeted by the present invention are cell migration, secretion of toxic products and proteolysis at a site of inflammation. Reduction of inflammation manifestations and reactions occurs by using an anti-S100 polynucleotide or polypeptide inhibitor or antagonist, which is essentially targeted against S100A8, S100A9 or S100A12, alone or in combination with other inhibitors of chemokines or immune modulating products. | 10-17-2013 |
20140348849 | Compounds and Method for Modulating Inflammatory Reactions - The present invention relates to compounds and methods for modulating, reducing or inhibiting, inflammatory reactions in a patient. Particularly, inflammatory reactions that are targeted by the present invention are cell migration, secretion of toxic products and proteolysis at a site of inflammation. Reduction of inflammation manifestations and reactions occurs by using an anti-S100 polynucleotide or polypeptide inhibitor or antagonist, which is essentially targeted against S100A8, S100A9 or S100A12, alone or in combination with other inhibitors of chemokines or immune modulating products. | 11-27-2014 |
Patryck Rouleau, L'Ancienne-Lorette CA
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20140042697 | CARD DEALING SHOE - A card dealing shoe with card reading capability for facilitating play of card games includes a control system configured to detect the existence of an alarm condition and a card restraining apparatus mounted on the elongated housing and configured for alternating between a non-restraining condition and a restraining condition, wherein the restraining condition includes activation of a physical restraint that prevents cards from being added to and removed from the card receiving or staging area in the card dealing shoe, wherein the card restraining apparatus is in communication with the control system and actuated from the non-restraining condition to the restraining condition responsive to the detection of an alarm condition. | 02-13-2014 |
20140291930 | CARD DEALING SHOE - A card dealing shoe including a sloped base with an opening, a roller mounted for rotational motion on an axle connected at each of the opposing side walls, and a pivoting lever having a first end and an opposing second end, wherein the first end protrudes from the opening in the sloped base, the pivoting lever being configured to pivot from a first position wherein the first end protrudes from the opening in the sloped base and the second end restricts rotational motion of the roller to a second position in which the second end permits rotational motion of the roller, wherein the lever is biased towards the first position. | 10-02-2014 |